1. Hyperparathyroidism Hub Links to overviews, clinical trials, treatment programs, images forhyperparathyroidism. hyperparathyroidism Hub. hyperparathyroidism http://www.healthubs.com/hyperparathyroidism/

Hyperparathyroidism Hub Hyperparathyroidism is a disorder of the parathyroid glands, caused by increased parathyroid hormone (PTH). It is diagnosed when tests show that blood levels of calcium as well as PTH are too high. Other diseases can cause high blood calcium levels, but only in hyperparathyroidism is the elevated calcium the result of too much PTH. Surgery to remove the enlarged gland is the only treatment for the hyperparathyroidism and cures it in 95 percent of cases. Acne Allergy Antibiotics Antioxidants ... Wedding Overviews - General Hyperparathyroidism by NIDDK Hyperparathyroidism from University of Connecticut Health Center Hyperparathyroidism from Catholic Healthcare West Hyperparathyroidism by the University of Maryland Medical System ... Fast Facts on Primary Hyperparathyroidism - from National Institute of Health, Osteoporosis and Related Bone Diseases, National Resource Center. Hyperparathyroidism - by David A. Allerheiligen, M.D., Joe Schoeber, M.D., Robert E. Houston, M.D., Virginia K. Mohl, M.D., and Karen M. Wildman, M.D., University of Wyoming, Casper, Wyoming. The Management of Recurrent or Persistent Hyperparathyroidism Persistent Hyperparathyroidism and Nephrocalcinosis - by J. Anthony Parker

2. Hyperparathyroidism Primary hyperparathyroidism is a disorder of the parathyroid glands. This epubfocuses on primary hyperparathyroidism. What Are the Parathyroid Glands? http://www.niddk.nih.gov/health/endo/pubs/hyper/hyper.htm

What Are the Parathyroid Glands? What Is Hyperparathyroidism? Why Are Calcium and Phosphorous So Important? What Causes Hyperparathyroidism? ... Further Reading Primary hyperparathyroidism is a disorder of the parathyroid glands. Most people with this disorder have one or more enlarged, overactive parathyroid glands that secrete too much parathyroid hormone. In secondary hyperparathyroidism, a problem such as kidney failure makes the body resistant to the action of parathyroid hormone. This e-pub focuses on primary hyperparathyroidism. What Are the Parathyroid Glands? The parathyroid glands are four pea-sized glands located on the thyroid gland in the neck . Occasionally, a person is born with one or more of the parathyroid glands embedded in the thyroid, the thymus, or elsewhere in the chest. In most such cases, however, the glands function normally. Though their names are similar, the thyroid and parathyroid glands are entirely separate glands, each producing distinct hormones with specific functions. The parathyroid glands secrete parathyroid hormone (PTH), a substance that helps maintain the correct balance of calcium and phosphorous in the body. PTH regulates release of the calcium from bone, absorption of calcium in the intestine, and excretion of calcium in the urine. When the amount of calcium in the blood falls too low, the parathyroid glands secrete just enough PTH to restore the balance.

3. New York Thyroid Center: Hyperparathyroidism hyperparathyroidism occurs when one or more of the parathyroid glands becomesenlarged and overactive, producing too much parathyroid hormone (PTH). http://cpmcnet.columbia.edu/dept/thyroid/hyperpara.html

Related Topics: Clinical Trials for Hyperparathyroidism Parathyroid Surgery Choosing a Surgeon New York Thyroid Center Home here are four parathyroid glands located in the neck, surrounding the thyroid gland. These glands produce parathyroid hormone (PTH) in order to keep the blood calcium level within the normal range. When blood calcium becomes too low, parathyroid hormone compensates by releasing calcium from the bones, by conserving calcium that would ordinarily be excreted by the kidneys, and by increasing absorption of calcium from food. Hyperparathyroidism occurs when one or more of the parathyroid glands becomes enlarged and overactive, producing too much parathyroid hormone (PTH). When this happens, the excess parathyroid hormone causes a high level of calcium to be released in the blood. Since the bones are the primary source of this calcium, hyperparathyroidism can result in excess bone loss or osteoporosis. If the condition is successfully treated, the bone loss can usually be reversed and bone density can be restored. Most cases (85%) of hyperparathyroidism are the result of a single parathyroid gland malfunctioning and developing into a benign tumor, known as an adenoma. In nearly all other cases (15%), two or more glands enlarge, again in a benign fashion, a condition called hyperplasia. Parathyroid cancer is a rare cause of primary hyperparathyroidism.

4. Hyperparathyroidism - Endocrinology Health Guide hyperparathyroidism is caused by overactive parathyroid glands. This guide covers symptoms, diagnosis and treatment weakening diseases). Other results of hyperparathyroidism are kidney stones, because of http://www.umm.edu/endocrin/hyperpar.htm

Endocrinology Health Guide... Pituitary Gland Disorders... Pancreas... Adrenal Glands... ... Glossary Related Resources Within UMM Endocrinology Joslin Diabetes Center School of Medicine Endocrinology Site Endocrinology Health Guide Hyperparathyroidism What is hyperparathyroidism? Hyperparathyroidism is caused by overactive parathyroid glands. Overactive parathyroid glands produce too much parathyroid hormones, which in turn stimulate increased levels of calcium in the blood stream. The excess calcium released by the bones leads to osteoporosis and osteomalacia (both bone-weakening diseases). Other results of hyperparathyroidism are kidney stones, because of high levels of calcium excreted into the urine by the kidneys. Causes of hyperparathyroidism include benign tumors on the parathyroid glands or enlargement of the parathyroid glands. What are symptoms of hyperparathyroidism? The following are the most common symptoms of hyperparathyroidism. However, each individual may experience symptoms differently. Symptoms may include: aches and pains depression abdominal pain nausea vomiting fatigue excessive urination confusion muscle weakness The symptoms of hyperparathyroidism may resemble other conditions or medical problems. Consult a physician for diagnosis.

5. Rancocas Valley Surgical Associates - Hyperparathyroidism hyperparathyroidism means that the parathyroid glands are producing an excess of a circulating in the bloodstream. Primary hyperparathyroidism has become a relatively common http://www.infosheet.com/surgery/parathyroid.html

Rancocas Valley Surgical Associates P.A Rancocas Medical Center 1000 Salem Road, Suite A Willingboro, New Jersey 08046-2855 fax: (609) 877-1589 Hyperparathyroidism means that the parathyroid glands are producing an excess of a hormone called parathyroid hormone, which in turn causes elevations in the levels of calcium circulating in the bloodstream. Primary hyperparathyroidism has become a relatively common condition, especially among the elderly. The incidence of this disease is approximately 25-28 cases/100,000 people per year. Among white women older than 60 the incidence actually approaches 190 cases/100,000 women/year. Parathyroid function The only role of the parathyroid in the human body is to regulate the levels of calcium in the bloodstream. Indirectly, therefore, the glands, working in unison in a normal situation, determine the strength and integrity of the bones. If there is too much calcium leached from the bones, then a condition called osteopenia and osteoporosis occurs. The parathyroid glands have no functional relationship to the thyroid gland. When the calcium levels get too high, typically above 10.5, the patient complains of abdominal pain, tiredness, irritability, depression, memory loss, and, sometimes, kidney stones. Many patients, however, have little or no complaints associated with the elevation in calcium. More often than not, today the discovery of hyperparathyroidism is associated with a routine blood test that finds an elevation in the blood calcium level.

6. Hyperparathyroidism: Overactivity Of The Parathyroid Glands. Over 45 pages on parathyroid disease and hyperparathyroidism. Writtenby experts for patients. SYMPTOMS OF hyperparathyroidism. http://www.endocrineweb.com/hyperpara.html

This parathyroid page was updated February 26, 2004. The primary disease of parathyroid glands is overactivity...too much parathyroid hormone is produced. This is called hyperparathyroidism. Under this condition of hyperparathyroidism, one or more of the parathyroid glands behaves inappropriately by making excess hormone regardless of the level of calcium. In other words, the parathyroid glands continue to make large amounts of parathyroid hormone even when the calcium level is normal and they should not be making hormone at all. Remember as you read these pages, its a hormone problem, not a cancer problem. We'll say it againHyperparathyroidism is a parathyroid hormone problem, NOT a parathyroid cancer problem! HOWEVER, over-production of parathyroid hormone by over-active parathyroid glands (hyperparathyroidism) can rob you of your health, making you feel run down and tired, causing osteoporosis and many other serious problems. KEEP READINGHyperparathyroidism can be fixed with new mini-surgery techniques in most people in under 20 minutes! (oftenunder 15 minutes!).

7. Familydoctor.org/handouts/251.html hyperparathyroidism What It Is and How It's TreatedA onepage overview. From a handout produced by the American Academy of Family Physicians. http://familydoctor.org/handouts/251.html

Advanced Search familydoctor.org Home Conditions A to Z Hyperparathyroidism What is hyperparathyroidism? What are the symptoms of hyperparathyroidism? What does HPT do to your body? Who gets HPT? ... How is HPT treated? Hyperparathyroidism: What It Is and How It's Treated Printer-friendly version Email this article What is hyperparathyroidism? You have 4 pea-sized glands behind the thyroid gland at the front of your neck. These glands are called parathyroids. They make a hormone called parathyroid hormone (PTH) that keeps the right levels of calcium in your blood and bones. PTH helps you absorb calcium from your food and keeps you from losing too much calcium in your urine. When your parathyroid glands make too much of this hormone, you have a condition called hyperparathyroidism (HPT). The amount of calcium going into your bones usually matches the amount of calcium passing out of your bones. This means that the amount of calcium in your bones should stay about the same all the time. If you have HPT, more calcium is coming out of your bones than is going in, so you get too much calcium in your blood. Other parts of your body don't work as well if you have too much calcium in your blood. Return to top What are the symptoms of hyperparathyroidism?

8. EMedicine - Hyperparathyroidism : Article By Philip Salen, MD hyperparathyroidism The parathyroid glands regulate calcium and phosphorus levels by releasing variable amounts of parathyroid hormone, which raises serum calcium levels while lowering serum hyperparathyroidism is a syndrome of hypercalcemia resulting from excessive release of Most cases of hyperparathyroidism are discovered accidentally when hypercalcemia is noted http://www.emedicine.com/emerg/topic265.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Endocrine And Metabolic Hyperparathyroidism Last Updated: May 19, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: parathyroid insufficiency, parathyroid hormone, PTH, parathyroid glands AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Philip Salen, MD , Research Director, Clinical Assistant Professor, Department of Emergency Medicine, Saint Luke's Hospital Editor(s): Joseph J Sachter, MD, FACEP , Consulting Staff, Department of Emergency Medicine, Muhlenberg Regional Medical Center; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, Pharmacy, eMedicine; Jeffrey L Arnold, MD, FACEP, FAAEM , Assistant Clinical Professor, Department of Emergency Medicine, Baystate Medical Center; John Halamka, MD

9. Hyperparathyroidism - April 15, 1998 - American Academy Of Family Physicians of this article, is provided on page 1807. hyperparathyroidism is a common cause of hypercalcemia The symptoms of hyperparathyroidism are vague and often similar to symptoms of http://www.aafp.org/afp/980415ap/allerhei.html

Advanced Search Articles Departments Patient Information Hyperparathyroidism DAVID A. ALLERHEILIGEN, M.D., JOE SCHOEBER, M.D., ROBERT E. HOUSTON, M.D., VIRGINIA K. MOHL, M.D., and KAREN M. WILDMAN, M.D., University of Wyoming, Casper, Wyoming A patient information handout on hyperparathyroidism , written by the authors of this article, is provided on page 1807. Hyperparathyroidism is a common cause of hypercalcemia. The hypercalcemia usually is discovered during a routine serum chemistry profile. Often, there has been no previous suspicion of this disorder. In most patients initially believed to be asymptomatic, previously unrecognized symptoms resolve with surgical correction of the disorder. The symptoms of hyperparathyroidism are vague and often similar to symptoms of depression, irritable bowel syndrome, fibromyalgia or stress reaction. Complications of primary hyperparathyroidism include peptic ulcers, nephrolithiasis, pancreatitis and dehydration. Surgical management is usually indicated. When medical management is used, routine monitoring for clinical deterioration is recommended. Preoperative localization of adenomas with technetium Tc 99m sestamibi scan is possible but may be unnecessary. An experienced surgeon should perform the parathyroidectomy. D uring the early 1970s, the advent of multichannel autoanalyzers and the "profiles" they produced appeared to increase the incidence of primary hyperparathyroidism fivefold, but the severity of the condition declined to an "asymptomatic" presentation.

10. Parathyroid An overview of this disease. A look at the diagnosis and methods of treating it. http://endocrinesearch.com/Parathyroid.htm

Parathyroid Thyroid Adrenal Pancreas ... Site Map Commonly asked questions and treatment information: What is a parathyroid gland? The parathyroid glands are small, endocrine glands situated in the neck that regulate calcium metabolism. Typically, most humans have 4 parathyroid glands, 2 on each side of the neck, however, approximately 8% of people will have either 3 or 5 glands. Each parathyroid gland, which is about the size of a small pea, produces a hormone called parathyroid hormone (PTH). PTH acts directly on the kidneys and bone to increase serum calcium levels, and indirectly on the gastrointestinal tract to enhance the intestinal absorption of calcium. The net effect of each of these mechanisms is an elevation in the serum calcium level. Figure 1: Calcium Metabolism What is hyperparathyroidism? Primary hyperparathyroidism is a common disease that occurs when one or more of the parathyroid glands become overactive. This leads to the overproduction of PTH, resulting in an abnormal elevation in serum calcium. In 85% of patients with primary hyperparathyroidism, the hypercalcemia is due to the benign enlargement of a single parathyroid gland, commonly referred to as a parathyroid adenoma. In 10%-15% of patients, primary hyperparathyroidism is caused by the enlargement of all 4 parathyroid glands, a state called parathyroid hyperplasia . In addition, up to 5% of patients can have a double adenoma, or enlargement of 2 parathyroid glands.

11. Hyperparathyroidism - General Practice Notebook Clinicallyoriented information. http://www.gpnotebook.co.uk/MedwebPage.cfm?ID=-731185144

12. Hyperparathyroidism a CHORUS notecard document about hyperparathyroidism Feedback. Search. hyperparathyroidism. 1' 2' - brown tumor +++ ++ chondrocalcinosis + rare osteosclerosis rare http://chorus.rad.mcw.edu/doc/00669.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system Feedback Search hyperparathyroidism 1' 2' - - brown tumor +++ ++ chondrocalcinosis + rare osteosclerosis rare +++ periostitis rare + see: renal osteodystrophy Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 26 May 2004 Medical College of Wisconsin

13. The Methodist Hospital - Data Not Available Methodist Health Care System gives a brief overview of this disorder and its symptoms and diagnosis. http://www.methodisthealth.com/endocrin/hyperpar.htm

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14. Parathyroid Surgery For Hyperparathyroidism Overview of Standard Parathyroid Surgery For Primary hyperparathyroidism. MOSTpatients can have an outpatient procedure to cure hyperparathyroidism. http://www.endocrineweb.com/standardpara.html

Overview of Parathyroid Surgery Since 1925, the gold standard treatment for primary hyperparathyroidism has been to surgically remove the parathyroid gland (or glands) which are overproducing hormone. Remember, this is a hormone problem, so the goal is to remove the source of the excess hormone (remove the bad parathyroid gland, leave the normal parathyroid glands). The ' standard parathyroid operation ' has not changed since its invention in 1925, and is performed by putting the patient to sleep under general anesthesia, an incision is made in the neck and the thyroid gland is mobilized to allow the surgeon to identify the four parathyroid glands which reside moderately deep in the neck behind the thyroid. Patients are typically hospitalized over night, and occasionally as long as a day or two. The incision has to be made of sufficient length to allow the surgeon adequate exposure of the numerous important structures in the neck, and thus it is typically five to seven (or even 10) inches long. These wounds eventually heal quite nicely. Parathyroid, parathyroid surgery, parathyroid operation

15. BCI-Home Discovers, develops and commercializes dhormones for treatment of hyperparathyroidism associated with end-stage renal disease, renal osteodystrophy, osteoporosis, psoriasis, prostate and breast cancer. (Nasdaq BCII). http://www.bonecare.com/

Welcome! Bone Care International is an innovative pharmaceutical company dedicated to improving patient outcomes by delivering unsurpassed Vitamin D hormone therapies. Bone Care is committed to discovering, developing and commercializing products by fostering a high performing corporate culture which values employees and promotes an entrepreneurial spirit. Please follow the links to the left for more information

16. NPS Pharmaceuticals Discovers and develops orally active, small molecule drugs which target cell surface receptors and ion channels for treatment of disorders such as hyperparathyroidism, osteoporosis, stroke and head trauma, epilepsy and bipolar disorder. (Nasdaq NPSP). http://WWW.NPSP.COM/

Welcome to NPS Pharmaceuticals NPS "Pharmindustrial" Design is being exhibited at The National Museum of Women in the Arts in Washington, D.C. Click here for more details. NPS 10 Year Anniversary at NASDAQ New York, NY Wednesday, May 26, 2004 webcast NPS Pharmaceuticals is currently developing drug candidates ranging from the earliest stages of discovery research to late-stage clinical trials. Several of these drugs target diseases and disorders that represent poorly met or unmet medical needs. These conditions affect some of the most important systems in the human body including: skeletal endocrinological gastrointestinal central nervous system The commitment of the people of NPS Pharmaceuticals is to build an enduring worldwide company, the purpose of which is to develop innovative drugs to maintain human health and relieve suffering. This commitment is founded on principles of honesty , hard work, respect, the constant quest for knowledge, and the realization of marketplace success.

17. The Paget Foundation - For Paget's Disease Of Bone And Related Disorders Information and programs for patients and medical professionals on Paget's disease of bone, primary hyperparathyroidism, fibrous dysplasia, osteopetrosis, breast cancer metastatic to bone, and prostate cancer metastatic to bone. http://www.paget.org

This website includes information for patients and health professionals on the following bone diseases and conditions: Paget's disease of bone, primary hyperparathyroidism, fibrous dysplasia, osteopetrosis (not osteoporosis) and the complications of some cancers to the bones. This website does not include information on Paget's breast disease. Information For Patients/General Public History Of The Paget Foundation 1978-2003 Paget's Disease of Bone Primary Hyperparathyroidism Fibrous Dysplasia ... Osteopetrosis Breast Cancer Metastatic to Bone (Publications are currently being revised.) Prostate Cancer Metastatic to Bone (Publications are currently being revised.) Information For Health Professionals Paget's Disease of Bone Fibrous Dysplasia Osteopetrosis - 2004 PAGET FOUNDATION RESEARCH AWARDS - PAGET'S DISEASE GUIDELINES AND APPLICATION HYPERPARATHYROIDISM GUIDELINES AND APPLICATION - FIRST EUROPEAN CONFERENCE ON PAGET'S DISEASE OF BONE - INFORMATION AVAILABLE AT http://www.unisi.it/eventi/paget A Brief Overview The Paget Foundation, founded in 1978, is a national voluntary health agency located in New York, NY. It is named for Sir James Paget, the eminent British surgeon who first identified Paget's disease of bone. Dr. Paget also discovered other diseases including Paget's disease of the breast and Paget's disease of the vulva.

18. New York Thyroid Center: Clinical Trials For Hyperparathyroidism he Metabolic Bone Disease Program is seeking people interested in participatingin experimental treatments for hyperparathyroidism and osteoporosis. http://cpmcnet.columbia.edu/dept/thyroid/parastudies.html

Related Topics: Hyperparathyroidism Parathyroid Surgery Choosing a Surgeon New York Thyroid Center Home he Metabolic Bone Disease Program is seeking people interested in participating in experimental treatments for hyperparathyroidism and osteoporosis. There are currently two projects available to eligible patients. If you are interested in learning more about these conditions and joining these projects, call Study #1: Combination Therapy Using Alendronate (Fosamax) and Parathyroid Hormone (PTH) in the Treatment of Postmenopausal Osteoporosis Study #2: Raloxifene (Evista) in Primary Hyperparathyroidism Combination Therapy Using Alendronate (Fosamax) and Parathyroid Hormone (PTH) in the Treatment of Postmenopausal Osteoporosis Columbia Presbyterian Medical Center is currently looking for women who are interested in taking part in a study to investigate a new treatment for osteoporosis. Osteoporosis (sometimes called "brittle bones") is a condition in which bone mass and bone strength is reduced so that fractures occur much more easily. This study will evaluate the effectiveness of combining PTH and Fosamax in treating osteoporosis. Studies have shown that both PTH, a hormone which has not been approved for use outside of research studies and Fosamax, a drug which has been approved for the treatment and prevention of osteoporosis, lead to an increase in bone mineral density. PTH alone has shown in past studies to lead to an increase in bone mineral density that is greater than currently available therapies.

19. Endocrine Surgery At Johns Hopkins The Johns Hopkins Medical Institutions Endocrine Surgery Web. Thyroid, hyperparathyroidism, adrenal, and carcinoid tumors. An online discussion area. http://www.path.jhu.edu/endocrine

THE JOHNS HOPKINS MEDICAL INSTITUTIONS Endocrine Surgery Web Endocrine Surgery at Johns Hopkins The Endocrine Surgery site has merged with the Department of Medicine's sites related to endocrine disorders. The discussion board is still active. Please see the following sites for more information. Thyroid Tumor Center Division of Endocrinology and Metabolism Division of Pediatric Endocrinology The Kelly G. Ripken Program at Johns Hopkins For information about thyroid tumors, please see http://www.thyroid-cancer.net/ Help Feedback Pathology Home ... Search Logout Last Modified: 08/12/2002

20. MDchoice.com The Ultimate Medical Information Finder Primary Hyperparathyroidism MDchoice.com Explanation of this disorder, the importance of calcium and phosphorous, causes, symptoms, diagnosis, treatment and surgery. http://www.mdchoice.com/Pt/consumer/Hyperparathyroidism.asp

Advertisement Sign up for a FREE disease newsletter: Select Disease Allergies Arthritis Cholesterol Depression Diabetes Hypertension Medical Information Arthritis Center Allergy Center Kid's Health Cancer Center ... Health News From our Sponsors Interactive Education Simulators PhotoRounds Medical Databases MEDLINE CancerLit AIDSLine Healthcare Employment About Us Editorial Board Our Company Contact Us We subscribe to the HONcode principles of the Health On the Net Foundation Spell Checker Search the Web's best medical sites Searches over 6,000 Medical Journals Health Information Wednesday, June 02, 2004 Find more information about this topic from either the Web or the world's best medical journals by using the search boxes at the top of this page. Hyperparathyroidism Disorder What Are the Parathyroid Glands? What Is Hyperparathyroidism? Why Are Calcium and Phosphorous So Important? What Causes Hyperparathyroidism? ... Further Reading Primary hyperparathyroidism is a disorder of the parathyroid glands. Most people with this disorder have one or more enlarged, overactive parathyroid glands that secrete too much parathyroid hormone. In secondary hyperparathyroidism, a problem such as kidney failure makes the body resistant to the action of parathyroid hormone. This e-pub focuses on primary hyperparathyroidism.

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