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         Hyperinsulinemia:     more detail
  1. Hyperinsulinemia: Webster's Timeline History, 1967 - 2007 by Icon Group International, 2009-02-20
  2. Hyperinsulinemia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications, 2004-10-08
  3. Hyperinsulinemia, Not Ovaries, at Core of PCOS.: An article from: Family Practice News by Bruce Jancin, 2001-01-15
  4. Dizziness, hyperactive caloric responses, otic capsule demineralization, impaired glucose tolerance, and hyperinsulinemia.(VESTIBULOLOGY CLINIC): An article from: Ear, Nose and Throat Journal by Kenneth H. Brookler, 2006-04-01
  5. Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood.(Research): An article from: Environmental Health Perspectives by Theodore A. Slotkin, Kathleen K. Brown, et all 2005-10-01
  6. Colorectal Ca may be linked to diabetes; hyperinsulinemia.(Clinical Rounds): An article from: Family Practice News by Mitchel L. Zoler, 2004-06-15
  7. Hyperinsulinemia and obesity are linked to PCOS in teens.(Metabolic Disorders)(polycystic ovary syndrome): An article from: Family Practice News by Diana Mahoney, 2007-11-15
  8. Pediatric Articles of Note for the Dermatologist. (DR. HOWARD B. PRIDE'S PICKS).(* Acanthosis nigricans and hyperinsulinemia.)(* Genetic abnormality in ... pain.): An article from: Skin & Allergy News by Betsy Bates, 2001-11-01
  9. Hyperinsulinemia a risk factor for breast cancer.(NEWS)(Report): An article from: Internal Medicine News by Bruce Jancin, 2009-06-15
  10. Metabolic syndrome: Cardiovascular disease, Diabetes mellitus, Insulin resistance, Equine metabolic syndrome, Etiology, Lipodystrophy, Chronic Somogyi rebound, Hyperinsulinemia, Gerald Reave
  11. Diabetes, Insulin and Alzheimer's Disease (Research and Perspectives in Alzheimer's Disease)
  12. METABOLIC SYNDROME AND ITS EVOLVING LINK TO DIABETES With growing knowledge of genetic factors and lifestyle issues, will prevention be far behind? (Postgraduate Medicine) by MBChB, FRCP(C) R. Cooppan, 2010-05-19

1. Hyperinsulinemia
hyperinsulinemia. hyperinsulinemia is an endocrine disorder characterizedby a failure of our Blood Sugar Control System (BSCS) to work properly.
http://www.healingmatters.com/hyperin.htm
Hyperinsulinemia Hyperinsulinemia is an endocrine disorder characterized by a failure of our B lood S ugar C ontrol S ystem ( BSCS ) to work properly. It manifests when Insulin progressively loses its effectiveness in sweeping the blood Glucose from the blood stream into the sixty seven trillion or so cells that constitute our bodies. Insulin levels in the blood rapidly rise to damaging levels and, together with the resulting elevated Glucose levels, account for much of the damage to our Arteries and Vascular system. When Insulin loses its effectiveness this loss is not due to any change in the Insulin produced by the Pancreas. It is due to a change in the cellular metabolism of almost every cell in our body. Although our Insulin has not changed, our cell metabolism has changed. Our cells no longer respond to blood borne Insulin signalling as they should. Our Blood Sugar Control System works like any type 0, negative feedback system to maintain our blood sugar at a predetermined setpoint. This setpoint is below the threshold where excess Glucose can cause Vascular damage. And the Insulin required to do this is normally below the threashold where it will cause Arterial or Vascular damage. When the Blood Sugar Control System is working right, it automatically, without our concious knowledge, maintains correct blood sugar with a minimum amount of Insulin whether we have just eaten a meal or been fasting and exercising for a week. When our system starts to exhibit Hyperinsulinemia, our Pancreatic Beta cells simply increase Insulin production and for a time this maintains our ability to swiftly lower post prandial (after eating) blood Glucose. For a time this maintains normal Glucose levels, albeit by the secretion of these abnormally high Insulin levels.

2. Healing Matters
disease. It has been known since the 1950 s as Insulin Resistant Diabetes,hyperinsulinemia, or Insulin Resistant hyperinsulinemia.
http://www.healingmatters.com/
Diabetes-Type II diabetes-Hypoglycemia-Obesity-Type I diabetes-impotence-Atherosclerosis-Heart failure-Stroke-Drugs-Nutrition
"Today, almost half of our population suffers from a degenerative disease that directly causes Heart Failure, Stroke, Type 2 Diabetes, Kidney Failure, Impotence, Obesity, Neuropathy, Retinopathy and a host of other similar symptoms. It is thought to be implicated, but not yet proven to be causal, in ADHD, ADD and some forms of Cancer. Its beginning symptoms are so mild that most who exhibit them do not realize that they are under a sentence of premature death and disability. It affects adults and children of all ages. At the turn of the last century this disease was so rare that many doctors could not correctly identify it. Today this disease forms such an important economic pillar in the medical community that every doctor in the country can easily recognize it at a glance."
    In a time of universal deceit, telling the truth is a revolutionary act.
      George Orwell
    Introduction
      This website is about a disease syndrome. It is a disease syndrome that is so common that all of us either have the disease or we know someone that does have it. It is a primary, if not the primary, economic support for a medical community whose policy level management has absolutely no interest in curing it. This one disease syndrome alone accounted for over 40% of the deaths in the US from

3. Insulin Resistance And Hyperinsulinemia
INSULIN RESISTANCE AND hyperinsulinemia. What are insulin resistance (IR)and hyperinsulinemia? How is hyperinsulinemia related to Leptin?
http://www.health-alliance.com/hospitals/Jewish/glueck/insulin_resistance.htm
Home Hospitals Jobs webBabies ... News INSULIN RESISTANCE AND HYPERINSULINEMIA What are insulin resistance (IR) and hyperinsulinemia? Beta cells in the pancreas produce insulin. Insulin stimulates uptake of glucose (sugar) from the blood to the cells in the body. When the body's cells are resistant to the action of the insulin, it is called insulin resistance (IR). As a result of the insulin resistance, the pancreas produces much more insulin than normal. This is called hyperinsulinemia (Figures 1,2). As an example, in a normal person, 1 unit of insulin might be needed to help 10 mg of glucose go into the cell, but in a hyperinsulinemic person, 10 units of insulin might be needed to get the same 10 mg of glucose into the cell (Figure 2). With hyperinsulinemia and IR come a myriad of problems including the following:
  • high triglycerides (increased risk of heart and stroke) high plasminogen activator inhibitor activity (PAI-Fx), causing increased risk of clotting low HDL cholesterol (increased risk of heart attack and stroke) high uric acid (gout) polycystic ovary syndrome (endocrine disorder with oligo-amenorrhea, infertility, hirsutism, obesity, high Leptin levels

4. Introduction: Hyperinsulinemia - WrongDiagnosis.com
Introduction to hyperinsulinemia as a medical condition including symptoms,diagnosis, misdiagnosis, treatment, prevention, and prognosis.
http://www.wrongdiagnosis.com/h/hyperinsulinemia/intro.htm
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Current chapter: Hyperinsulinemia Next sections Basic Summary for Hyperinsulinemia Causes of Hyperinsulinemia Symptoms of Hyperinsulinemia Diagnostic Tests for Hyperinsulinemia ... Complications of Hyperinsulinemia Next chapters: Neuropathic pain Meralgia parenthetica Myofascial pain syndromes Porphyria ... Feedback
Introduction: Hyperinsulinemia
Hyperinsulinemia: Hyperinsulemia means having too much insulin in the bloodstream. Hyperinsulemia is a common condition in Type 2 diabetes with underlying cause of insulin resistence . It is a somewhat paradoxical situation because you can be diabetic and still have too much insulin in your body. Ordinarily, too much insulin would lead to a low ( hypo ), but with insulin resistence, the body cannot use the insulin that it has, and for various reasons the pancreas actually produces more insulin leading to an excess of insulin in the bloodstream.

5. EMedicine - Hyperinsulinemia : Article By Kenneth Kwok-Chun Chan, MD
hyperinsulinemia Primary hyperinsulinism is a rare but importantcause of hypoglycemia in infants and children. hyperinsulinemia.
http://www.emedicine.com/PED/topic1075.htm
(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Endocrinology
Hyperinsulinemia
Last Updated: October 24, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: hyperinsulinemia, beta-cell hyperplasia, hyperinsulinemic hypoglycemia, nesidioblastosis AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography
Author: Kenneth Kwok-Chun Chan, MD , Consulting Staff, Department of Pediatrics, Andover Pediatrics Coauthor(s): Ab Sadeghi-Nejad, MD , Chief, Division of Pediatric Endocrinology and Metabolism, New England Medical Center; Professor, Department of Pediatrics, Tufts University School of Medicine Kenneth Kwok-Chun Chan, MD, is a member of the following medical societies: American Academy of Pediatrics , and Massachusetts Medical Society Editor(s): Thomas A Wilson, MD , Director of Pediatric Endocrinology, Clinical Associate Professor, Department of Pediatrics, State University of New York at Stony Brook; Mary L Windle, PharmD

6. EMedicine - Hyperinsulinemia : Article Excerpt By: Kenneth Kwok-Chun Chan, MD
hyperinsulinemia Primary hyperinsulinism is a rare but important cause of hypoglycemiain infants and children. (advertisement). Excerpt from hyperinsulinemia.
http://www.emedicine.com/ped/byname/hyperinsulinemia.htm
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Excerpt from Hyperinsulinemia
Synonyms, Key Words, and Related Terms: hyperinsulinemia, beta-cell hyperplasia, hyperinsulinemic hypoglycemia, nesidioblastosis
Please click here to view the full topic text: Hyperinsulinemia
Background: Primary hyperinsulinism is a rare but important cause of hypoglycemia in infants and children. It is the most common cause of neonatal hypoglycemia following the first few hours of life. The clinical presentation varies with the age of the child. Early diagnosis and treatment are essential to prevent seizures and neurologic sequelae. Persistent hypoglycemia and inappropriately high concentrations of insulin are diagnostic findings. The concentrations of free fatty acids and ketones (ie, beta-hydroxybutyrate, acetoacetate) are low. Several genetic causes of persistent hyperinsulinism recently have been identified. Pathophysiology: The differential diagnosis of hypoglycemia is extensive, and determining the underlying cause often is difficult. An understanding of glucose homeostasis can help narrow the differential diagnosis. In the fasting state, glucose is provided through glycogenolysis in the liver. After a few hours of fasting, insulin levels fall, and increased lipolysis creates free fatty acids and glycerol. Fatty acids do not cross the blood brain barrier and, therefore, are not used by the brain. However, fatty acids are used by the heart and muscle. Increased free fatty acids result in production of ketones, and the brain is able to metabolize ketones as an alternative source of fuel.

7. Low Carb Research & Studies - Insulin And It's Metabolic Effects
That insulin resistance is associated with the hyperinsulinemia that produces allof the cocalled chronic diseases of aging or at least contributes to them.
http://www.lowcarb.ca/articles/article149.html
Atkins diet and low carbohydrate diet resources provided free for information purposes, NOT as medical advice.
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A sugar-free zone
Low-Carb Plans Low-Carb Tips Low-Carb Recipes Low-Carb Tools ... Success Gallery
Low Carb studies, research and media clips about Atkins diet and low-carb diets. Arguments for and against are presented here for objectivity. In our opinion, arguments against low-carb dieting are based on false, simplistic assumptions. How I Became a Low Carb Believer Low carbohydrate diet helps diabetics Studies suggest Atkins diet is safe A high-carb diet increases the risk of heart disease ... More Low Carb News Featured articles: Which low-carb plan is right for me? First low carb diet book ever, since 1860's Studies suggest Atkins diet is safe! Low carb Tiramisu recipe! ... Carbohydrate Counter Discuss this article!
Low-Carb Diet Research and News Ron Rosedale, M.D.
Insulin and It's Metabolic Effects
Presented at Designs for Health Institute's BoulderFest August 1999 Seminar

Let's go to something totally different, a lady with severe osteoporosis. She is almost three standard deviations below the norm in both the hip femeral neck and the cervical vertebrae, and she is very worried about getting a fracture. A fairly young woman and she was put on a high carbohydrate diet and told that would be of benefit, and placed on estrogen, which is a fairly typical treatment. They wanted to put her on some other medicines and she didn't want to, she wanted to know if there was an alternative. Although we didn't have as dramatic a turn around, we got her to one standard deviation below the norm in a year, taking her off the estrogen she was on, anyway.

8. Diabetes In Control Dot Com.
Hypertension and hyperinsulinemia. hyperinsulinemia can be caused by insulin resistance,which creates elevated glucose levels due to glucose intolerance.
http://www.diabetesincontrol.com/jakescorner/i138.shtml

Advertise Classifieds New Products Links ... Test Your Knowledge Hypertension and Hyperinsulinemia
By Dr. Brian P. Jakes, Jr.
Hypertension is defined as the sustained elevation of either or both systolic and diastolic blood pressure while at rest. There are several different classifications of hypertension, but the two main categories are primary, also called essential hypertension, and secondary hypertension. The majority of all those diagnosed with hypertension fall under the primary category while only a small percentage are classified as secondary hypertensive. Secondary hypertension is the result of some other condition or disease where as primary hypertension is said, by conventional medicine, to have no identifiable cause for development. An overwhelming number of studies have revealed that diet, obesity and vitamin and mineral deficiencies are related to primary hypertension. Changes in lifestyle and the uses of specific supplements have proven to be extremely effective in the treatment and reversal of mild primary hypertension and could be considered prior to the use of prescription drugs Hypertension is strongly associated with the development of cardiovascular disease and is one of the major factors in the incidences of heart attacks in both the diabetic and non-diabetic population. It can also contribute to the progression of atherosclerosis. Numerous studies show a definite correlation between hypertension, diabetes, hyperglycemia, atherosclerosis and cardiovascular disease.

9. Insulin Resistance And Hyperinsulinemia
As one would suspect, insulin resistance and subsequent hyperinsulinemiahave also been linked to an increased risk of cardiovascular disease.
http://www.wfp50427.w1.com/insulin_resistance_and_hyperinsulinemia.htm
Peripheral tissue resistance to the effects of insulin has been strongly connected to glucose intolerance, and the emergence of type 2 diabetes. Although often seen in obese individuals, this is independent of obesity or waist circumference. For an excellent discussion of the role of insulin resistance, read the 1997 American Diabetes Association Consensus Development Conference report Haffner et al (1995) report on their follow up of 714 Mexican-American participants in the San Antonio Heart Study. Ninety-one (91) of these subjects developed type 2 diabetes by the time of follow up. Looking at both fasting insulin levels (as an indicator of insulin resistance) and at the change in insulin levels in response to changes in glucose load (as a measure of insulin secretion), they found that both increased resistance and decreased insulin secretion at baseline independently predicted those patients who later were diagnosed with type 2 diabetes. Forty-four of the 91 patients identified at follow-up had normal glucose tolerance tests, but evidence of insulin resistance; other patients had impaired glucose tolerance on testing. As one would suspect, insulin resistance and subsequent hyperinsulinemia have also been linked to an increased risk of cardiovascular disease. The so-called

10. HealthlinkUSA Hyperinsulinemia Links
Kanoodle.com. Try searching for hyperinsulinemia at ExactSeek.com. Click here forpage 1 of hyperinsulinemia information from the HealthlinkUSA directory.
http://www.healthlinkusa.com/432ent.htm

11. Hyperinsulinemia; Treatment, Prevention, Cure
hyperinsulinemiaSearch information from many of the best hyperinsulinemia healthsites. Quickly find information treatments, prevention, support and more.
http://www.healthlinkusa.com/content/432.html
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Arthritis and Your Health ... Women's Health Wednesday June 02, 2004 Spina Bifida:
Spina Bifida is a rare birth disorder, affecting approximately 1 in 12-1400 live births. Click here to learn more Craniosynostosis: Sagittal Synostosis...males are affected about three times as often as females. Click here to learn more Spinal Cord Injury: Acts of violence have now overtaken falls as the second most common source of spinal cord injury.

12. Entrez PubMed
Click here to read hyperinsulinemia as an independent risk factorfor ischemic heart disease. Despres JP, Lamarche B, Mauriege P
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8

13. Entrez PubMed
Diet, lifestyle, and colorectal cancer is hyperinsulinemia the missinglink? Kim YI. Department of Medicine, St. Michael s Hospital
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9

14. MayoClinic.com - Hyperinsulinemia
hyperinsulinemia. What can you tell me about a disease called hyperinsulinemia? Theterm hyperinsulinemia means abnormally high levels of insulin in your blood.
http://www.mayoclinic.com/invoke.cfm?id=HQ00896

15. MayoClinic.com - Hyperinsulinemia
The term i hyperinsulinemia /i means abnormally high levels of insulinin your blood. It More Information. hyperinsulinemia. What
http://www.mayoclinic.com/invoke.cfm?id=HQ00896&si=2318

16. Hyperinsulinaemia From On-line Medical Dictionary
hyperinsulinemiahyperinsulinemia. hyperinsulinemia refers to high insulin levels inthe blood. The pancreas for hyperinsulinemia. hyperinsulinemia may
http://cancerweb.ncl.ac.uk/cgi-bin/omd?hyperinsulinaemia

17. Clinical Trial: Randomized Study Of Decreased Hyperinsulinemia On The Ovulatory
Randomized Study of Decreased hyperinsulinemia on the Ovulatory Response to ClomipheneCitrate in Women With Polycystic Ovary Syndrome. This study is completed.
http://www.clinicaltrials.gov/ct/gui/show/NCT00005104;jsessionid=BE6EF432EB7640B

18. Clinical Trial: Randomized Study Of The Effect Of Decreased Hyperinsulinemia On
Randomized Study of the Effect of Decreased hyperinsulinemia on the Ovulatory Responseto Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome.
http://www.clinicaltrials.gov/ct/gui/show/NCT00005654?order=2

19. Hyperinsulinemia: The Missing Link Among Oxidative Stress And Age-related Diseas
National Library of Medicine s PubMed directory of MEDLINE citations. hyperinsulinemiathe missing link among oxidative stress and agerelated diseases?
http://www.arclab.org/medlineupdates/abstract_11118820.html
Aging Research Center Home Page All Previous Aging Related Articles On-line Medical Dictionary National Library of Medicine's PubMed directory of MEDLINE citations.
Hyperinsulinemia: the missing link among oxidative stress and age-related diseases?
- Facchini FS, Hua NW, Reaven GM, Stoohs RA Free Radic Biol Med 2000 Dec 15;29(12):1302-6. Mounting evidence supports Harman's hypothesis that aging is caused by free radicals and oxidative stress. Although it is known that oxidant species are produced during metabolic reactions, it is largely unknown which factor(s), of physiological or pathophysiological significance, modulate their production in vivo. In this hypothesis paper, it is postulated that hyperinsulinemia may have such function and therefore promote aging, independently of elevations of glycemia. Hyperinsulinemia is secondary to impaired insulin stimulated glucose metabolism at the level of skeletal muscle (insulin resistance) and is seen in about one third of glucose tolerant humans following dietary carbohydrate intake. If other insulin-stimulated (or inhibited) pathways retain normal

20. Temporal Association Between Obesity And Hyperinsulinemia In Children, Adolescen
Temporal association between obesity and hyperinsulinemia in children,adolescents, and young adults the Bogalusa Heart Study.
http://www.arclab.org/medlineupdates/abstract_10421238.html
Aging Research Center Home Page All Previous Aging Related Articles On-line Medical Dictionary National Library of Medicine's PubMed directory of MEDLINE citations.
Temporal association between obesity and hyperinsulinemia in children, adolescents, and young adults: the Bogalusa Heart Study.
- Srinivasan SR, Myers L, Berenson GS Metabolism 1999 Jul;48(7):928-34. Obesity is generally associated with hyperinsulinemia. However, whether obesity precedes or follows hyperinsulinemia is not clear. The present study examined the temporal nature of the association between obesity and hyperinsulinemia in a biracial (black-white) community-based population enrolled in the Bogalusa Heart Study. Three longitudinal cohorts of children (n = 427; baseline age, 5 to 7 years), adolescents (n = 674; baseline age, 12 to 14 years), and young adults (n = 396; baseline age, 20 to 24 years) were selected retrospectively, with a follow-up period of approximately 3 years. In general, longitudinal changes in the mean body mass index (kilograms per meter squared), an

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