1. MedlinePlus Medical Encyclopedia: Hereditary Angioedema hereditary angioedema. Also, see angioedema. Causes, incidence, and risk factors Return to top. hereditary angioedema is an inherited disorder. http://www.nlm.nih.gov/medlineplus/ency/article/001456.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Hereditary angioedema Contents of this page: Illustrations Definition Causes, incidence, and risk factors Symptoms ... Prevention Illustrations Antibodies Definition Return to top Hereditary angioedema is an inherited abnormality of the immune system that causes swelling , particularly of the face, and abdominal cramping. Also, see angioedema Causes, incidence, and risk factors Return to top Hereditary angioedema is an inherited disorder. It is caused by the absence of a protein called C1 inhibitor (or a defect in this protein), which in turn effects blood vessels. People with hereditary angioedema can develop rapid swelling of the hands, feet, limbs, face, intestinal tract, or airway (larynx or trachea). Unlike an allergic reaction , there is usually no itching or hives . Swelling of the gut can cause intestinal cramping. If swelling closes the airway, it can be fatal. Attacks of swelling can become more severe in late childhood and adolescence. A family history is usually noted, at times only reported to descendants as an unexpected, sudden, and premature death of a parent, aunt/uncle, or grandparent.

2. United States Hereditary Angioedema Association hereditary angioedema C1 Inhibitor Deficiency Disorder. hereditary angioedema (HAE) is a rare genetic disorder (autosomal dominant http://www.hereditaryangioedema.com/

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3. EMedicine - Angioedema, Hereditary : Article By Warren R Heymann, MD An in dept look at hereditary angioedema beginning with an introduction, clinical features, differentials, work up, treatment, medication and follow up. http://www.emedicine.com/derm/topic24.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Dermatology Allergy And Immunology Angioedema, Hereditary Last Updated: June 20, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: hereditary angioedema, HAE, C1-INH, C1 inhibitor, swelling of the skin AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Warren R Heymann, MD , Head, Division of Dermatology, Professor, Department of Internal Medicine, University of Medicine and Dentistry of New Jersey Warren R Heymann, MD, is a member of the following medical societies: American Academy of Dermatology American Society of Dermatopathology , and Society for Investigative Dermatology Editor(s): Robert A Schwartz, MD, MPH , Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School; Michael J Wells, MD

4. Medical Encyclopedia: Hereditary Angioedema (Print Version) Medical Encyclopedia hereditary angioedema. Also, see angioedema. Causes, incidence, and risk factors. hereditary angioedema is an inherited disorder. http://www.nlm.nih.gov/medlineplus/print/ency/article/001456.htm

To print this page, use the print option from your browser. To close this window, click on the "x" in the upper right hand corner of the window. Medical Encyclopedia: Hereditary angioedema URL of this page: http://www.nlm.nih.gov/medlineplus/ency/article/001456.htm Definition Hereditary angioedema is an inherited abnormality of the immune system that causes swelling, particularly of the face, and abdominal cramping. Also, see angioedema. Causes, incidence, and risk factors Hereditary angioedema is an inherited disorder. It is caused by the absence of a protein called C1 inhibitor (or a defect in this protein), which in turn effects blood vessels. People with hereditary angioedema can develop rapid swelling of the hands, feet, limbs, face, intestinal tract, or airway (larynx or trachea). Unlike an allergic reaction, there is usually no itching or hives. Swelling of the gut can cause intestinal cramping. If swelling closes the airway, it can be fatal. Attacks of swelling can become more severe in late childhood and adolescence. A family history is usually noted, at times only reported to descendants as an unexpected, sudden, and premature death of a parent, aunt/uncle, or grandparent.

5. Health And Medical Information: Diseases And Conditions, Medical Dictionary, Pro A brief article about hereditary angioedema. http://www.medicinenet.com/Script/Main/Art.asp?li=MNI&ArticleKey=3721

6. NEJM -- Hereditary Angioedema Editorial from The New England Journal of Medicine hereditary angioedema Airway Obstruction in Patients With hereditary angioedema Due to C1 Esterase Inhibitor C1 Inhibitor Concentrate in http://www.nejm.org/cgi/content/short/334/25/1666

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 334:1666-1667 June 20, 1996 Number 25 Next Hereditary Angioedema Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. Full Text Add to Personal Archive Add to Citation Manager E-mail When Cited ... PubMed Citation "So soon as ever she came into the room I recognized the affection, for there lay, across the face from temple to temple, an oblong tumor almost closing both eyes." Thus, J.L. Milton in 1876 described one of his patients with angioedema, six years before Quincke introduced the term angioneurotic edema to describe this disease. As Dr. Milton pointed out, the clinical syndrome can be identified quickly, but its cause is not so easy to discern. Because of the severity of the symptoms and the need for a specific therapeutic approach, angioedema due to deficiency of C1 inhibitor must Full Text of this Article References This article has been cited by other articles: Bork, K., Hardt, J., Schicketanz, K.-H., Ressel, N. (2003). Clinical Studies of Sudden Upper Airway Obstruction in Patients With Hereditary Angioedema Due to C1 Esterase Inhibitor Deficiency.

7. AllRefer Health - Hereditary Angioedema hereditary angioedema information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, tests, support groups http://health.allrefer.com/health/hereditary-angioedema-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Hereditary Angioedema Hereditary Angioedema Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Definition Hereditary angioedema is an inherited abnormality of the immune system that causes swelling , particularly of the face, and abdominal cramping. Also, see angioedema Antibodies Hereditary angioedema is an inherited disorder. It is caused by the absence of a protein called C1 inhibitor (or a defect in this protein), which in turn effects blood vessels. People with hereditary angioedema can develop rapid swelling of the hands, feet, limbs, face, intestinal tract, or airway (larynx or trachea).

8. Reader Digest Health hereditary angioedema, a general discussion, alternate names and resources. http://www.rd.com/common/nav/index.jhtml?articleId=8612968

9. AllRefer Health - Hereditary Angioedema Treatment You are here AllRefer.com Health Diseases Conditions hereditary angioedema Treatment of hereditary angioedema. hereditary angioedema. http://health.allrefer.com/health/hereditary-angioedema-treatment.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Hereditary Angioedema : Treatment of Hereditary Angioedema Hereditary Angioedema Definition Prevention Treatment Expectations or Prognosis Complications Calling Your Health Care Provider Go To Main Page Treatment Try to prevent attacks by avoiding trauma and precipitating factors. In contrast to other causes of angioedema (e.g., from allergies), antihistamines and other related treatments are of limited benefit in hereditary angioedema. Attenuated androgens, which are derivatives of normal sex hormones, can reduce the frequency and severity of attacks. Once an attack occurs, treatment includes pain relief and intravenous fluids. A new treatment using C1-inhibitor concentrate is being tested.

10. Hereditary Angioedema Treatment Genzyme Corp. and Dyax Corp. have announced a joint venture to continue the development of a drug to treat hereditary angioedema, a rare disease that causes attacks of subcutaneous, abdominal and/ http://rarediseases.about.com/b/a/003364.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') About Rare / Orphan Diseases Home Essentials ... Rare cancers zau(256,152,145,'gob','http://z.about.com/5/ad/go.htm?gs='+gs,''); Is it a Rare Disease? Rare Diseases A - B Rare Diseases C - D Rare Diseases E - H ... Help zau(256,138,125,'el','http://z.about.com/0/ip/417/0.htm','');w(xb+xb); Stay Current Subscribe to the About Rare / Orphan Diseases newsletter. zau(256,152,100,'hs','http://z.about.com/5/ad/hs.htm?zIhsid=00',''); Search Rare / Orphan Diseases Hereditary Angioedema treatment Rare/Orphan Diseases Blog Main June 28, 2003 Hereditary Angioedema treatment Genzyme Corp. and Dyax Corp. have announced a joint venture to continue the development of a drug to treat hereditary angioedema, a rare disease that causes attacks of subcutaneous, abdominal and/or laryngeal swelling. The drug, DX-88, is in Phase 2 clinical trials. Read Genzyme's press release to learn more. Email a Friend Display Latest Headlines Read Archives Most Popular ALD and Lorenzo's Oil The Elephant Man's Bones Reveal Mystery Prune Belly (Eagle-Barrett) Syndrome Progeria Syndromes ... Mad Cow Disease and Humans What's Hot Autoimmune Kidney Disease Tourette Syndrome Christmas Disease Bugs, PANDAS, and Tics

11. EMedicine - Angioedema, Hereditary : Article Excerpt By: Warren R Heymann, MD Angioedema, Hereditary hereditary angioedema (HAE) is an autosomal dominant disorder manifested by painless, nonpruritic swelling of the skin. Type I HAE is defined by low plasma levels of a Synonyms, Key Words, and Related Terms hereditary angioedema, HAE, C1-INH, C1 inhibitor http://www.emedicine.com/derm/byname/angioedema-hereditary.htm

(advertisement) Excerpt from Angioedema, Hereditary Synonyms, Key Words, and Related Terms: hereditary angioedema, HAE, C1-INH, C1 inhibitor, swelling of the skin Please click here to view the full topic text: Angioedema, Hereditary Background: Hereditary angioedema (HAE) is an autosomal dominant disorder manifested by painless, nonpruritic swelling of the skin. Type I HAE is defined by low plasma levels of a normal C1 inhibitor (C1-INH) protein. Type II HAE is characterized by the presence of normal or elevated levels of a dysfunctional C1-INH. Pathophysiology: The gene for C1-INH has been mapped to chromosome 11 (11q12-q13.1). C1-INH is a multifunctional serine protease inhibitor that is normally present in high concentrations in plasma. It is the only known plasma inhibitor of C1r and C1s, the activated proteases of the first component of complement. It is also the major plasma inhibitor of activated Hageman factor, the first protease in the contact system. Additionally, C1-INH is one of the major inhibitors of plasma kallikrein, the contact system protease that cleaves kininogen and releases bradykinin. Presumably, uncontrolled activation of the contact system allows for the release of kininlike mediators, resulting in edema of subcutaneous or submucosal tissues. HAE is due to mutations within the C1-INH gene and is transmitted as an autosomal dominant trait. Two variants of HAE exist: type I (85%) and type II (15%). Type I HAE is characterized by low antigenic and functional plasma levels of a normal C1-INH protein. Type II HAE is characterized by the presence of normal or elevated antigenic levels of a dysfunctional mutant protein together with reduced levels of the functional protein. C1-INH deficiency allows autoactivation of the first component of complement (C1) with consumption of C4 and C2.

12. Hereditary Angioedema - Information / Diagnosis / Treatment / Prevention home genetic disorders hereditary angioedema hereditary angioedema. MedicineNet.com Medical Dictionary A brief article about hereditary angioedema. http://www.healthcyclopedia.com/genetic-disorders/hereditary-angioedema.html

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... genetic disorders > hereditary angioedema Hereditary Angioedema Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Medical Definition Health News Web Directory: Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "hereditary angioedema" Health News: Search millions of published articles for news on Hereditary Angioedema Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Adam.com: An Overview A definition of hereditary angioedema along with a look at the causes, incidence and risk factors. E-Medicine: HAE An in dept look at hereditary angioedema beginning with an introduction, clinical features, differentials, work up, treatment, medication and follow up. Hereditary Angioedema Support Group A non profit Organization dedicated to those families that are touched by a rare blood disease known as Hereditary Angioedema MedicineNet.com - Medical Dictionary

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14. Angioedema, Unusual Presentations Unusual Presentations of hereditary angioedema and Acquired Angioedema. Introduction. hereditary angioedema has been known to exist for over a century. http://www.medical-library.org/journals/derm/angioede.htm

Current Clinical Strategies Publishing Home Table of Contents January, 2002Volume 324, Number 14, pp 891-1047 Unusual Presentations of Hereditary Angioedema and Acquired Angioedema Thomas J. Tsou, MD, FACEP Director of Pediatric Emergency Medicine King-Drew /University of California, Los Angeles Medical Center Los Angeles, California Mark D. Dixon, MD Assistant Program Director, Emergency Medicine Department King-Drew/University of California, Los Angeles Medical Center Los Angeles, California Bolanile Akinwole, MD Assistant Professor, Emergency Medicine Department King-Drew/University of California, Los Angeles Medical Center Los Angeles, California Mahmoud Nouh, MD Assistant Professor, Emergency Medicine Department King-Drew/University of California, Los Angeles Medical Center Los Angeles, California Eugene Hardin, MD, FACEP Chairman, Emergency Medicine Department King-Drew/University of California, Los Angeles Medical Center Los Angeles, California From the Department of Emergency Medicine King-Drew/UCLA Medical Center, Los Angeles, California

15. Angioedema, Hereditary hereditary angioedema is a rare inherited disorder characterized by an accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid http://hw.healthdialog.com/kbase/nord/nord98.htm

document.write(''); var hwPrint=1; var hwDocHWID="nord98"; var hwDocTitle="Angioedema, Hereditary"; var hwRank="1"; var hwSectionHWID="nord98"; var hwSectionTitle=""; var hwSource="us6.0"; var hwProdCfgSerNo="wsh_html_003_s"; var hwDocType="NORD"; National Organization for Rare Disorders, Inc. Angioedema, Hereditary Important It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Angioneurotic Edema, Hereditary C1-INH Complement Component 1 Inhibitor Deficiciency Complement Component C1, Regulatory Component Deficiency Esterase Inhibitor Deficiency HAE HANE Disorder Subdivisions C1 Esterase Inhibitor Deficiency, Type I, Angioedema C1 Esterase Inhibitor Dysfunction, Type II, Angioedema Related Disorders List Information on the following diseases can be found in the Related Disorders section of this report: Acquired Nonhereditary Angioedema Cutis Laxia General Discussion Hereditary Angioedema is a rare inherited disorder characterized by an accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway. Usually, this swelling is not accompanied by itching, as it might be with an allergic reaction. Swelling of the gastrointestinal tract leads to cramping. Swelling of the airway may lead to obstruction, a potentially very serious complication. These symptoms develop as the result of deficiency or improper functioning of certain proteins that help to maintain the normal flow of fluids through very small blood vessels (capillaries). In some cases, fluid may accumulate in other internal organs. The severity of the disease varies greatly among affected individuals.

16. Canadian Hereditary Angioedema Society http://www.haecanada.com/

17. HealthCentral - General Encyclopedia - Hereditary Angioedema General Health Encyclopedia, hereditary angioedema. Unlike hives from an allergic reaction, there is usually no itching with hereditary angioedema. http://www.healthcentral.com/mhc/top/001456.cfm

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18. HealthCentral - Pediatrics Encyclopedia - Hereditary Angioedema Pediatric Health Encyclopedia, hereditary angioedema. Unlike hives from an allergic reaction, there is usually no itching with hereditary angioedema. http://www.healthcentral.com/peds/top/001456.cfm

WELCOME! Receive Free Newsletters Join a Community SEARCH FOR: CONSUMER HEALTH INFORMATION TOPIC CENTERS Choose a topic Acne Alcohol Allergies Alternative Medicine Alzheimer's Anemia Arthritis Asthma Baby and Toddler Health Back Care Bipolar Disorder Birth Control Bodywork and Mind/Body Bowel Breast Cancer Cancer Overview Caregiving Chemotherapy Children's Health Cholesterol Circumcision Colds and Flus Colon Cancer Cosmetic Surgery Crohn's Disease Dental Depression Diabetes Diet Drugs Digestion Disabilities Drugs and Medications Eating Disorders Eczema Erectile Dysfunction Eye and Vision Fitness Foot Care GERD/Heartburn Hair Loss Hearing Heart and Circulation Hepatitis Herbs Herpes High Blood Pressure HIV and AIDS Home Remedies Hyperactivity and ADD Immunizations/Vaccines Impotence Incontinence/Bladder Infertility Leukemia Lung Cancer Medical Breakthroughs Medical Expenses Medical Marijuana Men's Health Menopause Mental Health Migraines and Headaches Multiple Sclerosis Nutraceuticals Nutrition and Healthy Eating Osteoporosis Pain Management Parenting Parkinson's Pregnancy and Childbirth Prostate Cancer Prostate Disorders Psoriasis Rheumatoid Arthritis Safety and First Aid Schizophrenia Senior Health Sex and Relationships Sexual Health Skin and Hair Sleep Disorders Smoking Stress Reduction Stroke Substance Abuse and Addiction Teen Health Thyroid Disorders Travel Health Vitamins and Supplements Weight Loss Women's Health Women's Reproductive Cancers Yeast Infection Yoga Search Tips Advertisement Advertisement Main Consumer Health Information Home News Dr. Dean Edell

19. Disease Directory : Genetic Disorders : Hereditary Angioedema Diseases Genetic Disorders hereditary angioedema. hereditary angioedema. C1 esterase inhibitor transfusions in patients with hereditary http://www.diseasedirectory.net/Genetic_Disorders/Hereditary_Angioedema/default.

Wednesday, June 02, 2004 Genetic Disorders Aarskog Syndrome Aase Syndrome Ablepharon-Macrostomia Syndrome ... Genetic Disorders : Hereditary Angioedema AllRefer Health - Hereditary Angioedema Treatment C1 esterase inhibitor transfusions in patients with hereditary ... - Guest editorial C1 esterase inhibitor transfusions in patients with hereditary angioedema Hereditary angioedema (HAE) is an autosomal dominant disease first de C1-esterase inhibitor transfusions in patients with hereditary ... - C1-esterase inhibitor transfusions in patients with hereditary angioedema DE Visentin, WH Yang, and J Karsh Background: Hereditary angioedema results from the Canadian Hereditary Angioedema Society - CAN logo www.calgaryallergy.ca. The Canadian Hereditary Angioedema Society (www.haecanada.com). Conditions and Diseases - Hereditary Angioedema Top Links - Hereditary Angioedema Web Site Links. Hereditary Angioedema Support Group - A non profit Organization dedicated to those families E-Medicine: HAE - An in dept look at hereditary angioedema beginning with an introduction, clinical features, differentials, work up, treatment, medication and follow up. Geometry.Net - Health_Conditions: Hereditary Angioedema

20. Disease Directory : Hereditary Angioedema HOME....... Diseases Genetic Disorders hereditary angioedema hereditary angioedema. Directory Listing. Title hereditary angioedema http://www.diseasedirectory.net/detailed/25617.aspx

Wednesday, June 02, 2004 Genetic Disorders Aarskog Syndrome Aase Syndrome Ablepharon-Macrostomia Syndrome ... Hereditary Angioedema : Hereditary Angioedema Directory Listing Title: Hereditary Angioedema Description: HOME. Hereditary Angioedema. Hereditary Angioedema; Hereditary Angioedema; ANGIONEUROTIC EDEMA, HEREDITARY; Hereditary Angioedema (HAE) - United Kingdom Report. HOME. Date Added: 2/16/2004 7:08:21 PM URL: http://www.bdid.com/heredangio.htm

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