21. Von Willebrand Disease Offers information about Von Willebrand disease. Includes the types, the symptoms, treatment, and heredity. http://www.hemophilia.ca/en/2.2.php

Von Willebrand Disease Von Willebrand Disease Introduction Types of Von Willebrand Disease Heredity Symptoms ... Precautions Researched and written by David Page Reviewed by David Lillicrap, M.D., FRCPC Personal Stories Related Articles

22. Medical Genetics - X-linked Recessive: Red-Green Color Blindness, Hemophilia A Inheritance of the condition, and similar mechanism in hemophilia. http://www.musckids.com/health_library/genetics/xlink.htm

Home About Us Departments Send an e-Card ... Your Hospital Visit 171 Ashley Ave. Charleston, SC 29425 800-424-MUSC Print Version Medical Genetics X-linked Recessive: Red-Green Color Blindness, Hemophilia A Genes are inherited from our biological parents in specific ways. One of the basic patterns of inheritance of our genes is called X-linked inheritance. What is X-linked inheritance? X-linked inheritance means that the gene causing the trait or the disorder is located on the X chromosome. Remember, females have two X chromosomes, while males have one X and one Y. Genes on the X can be recessive or dominant, and their expression in females and males is not the same because the genes on the Y chromosome do not exactly pair up with the genes on the X. X-linked recessive genes are expressed in females only if there are two copies of the gene (one on each X chromosome). However, for males, there only needs to be one copy of an X-linked recessive gene in order for the trait or disorder to be expressed. For example, a woman can carry a recessive gene on one of the X chromosomes unknowingly, and pass it on to a son, who will express the trait: Therefore, half of the daughters have the gene and can pass it to the next generation. The other half do not have the gene and, therefore, cannot pass it on. Half of the sons do not have the gene and cannot pass it on. The other half of the sons have inherited the gene and will express the trait or disorder.

23. Îáùåñòâî áîëüíûõ ãåìîôèëèåé/Association For Persons Wit Top/World/Russian/Здоровье/Заболевания/Гемофилия http://www.blood.ru/hemophilia/

24. Hemophilia a CHORUS notecard document about hemophilia Disclaimer. Feedback. Search. hemophilia. incidence knees elbows ankles hips shoulders wrists http://chorus.rad.mcw.edu/doc/01019.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system Feedback Search hemophilia incidence: knees > elbows > ankles > hips > shoulders > wrists results in secondary OA (DDx: acromegaly ochronosis spondyloepiphyseal dysplasia , chronic trauma) xray manifestations: premature closure of epiphysis leading to short bone with enlarged end "squared" patella (flattened inferiorly) widened intercondylar notch subchondral cysts severe osteopenia Cf: JRA Brian Funaki, MD - 6 February 1995 Last updated 26 May 2004 Medical College of Wisconsin

25. Hemophilia Of Georgia Home Page This site is dedicated to providing information on the opportunities available through hemophilia of Georgia for Georgia families who have hemophilia, von http://www.hog.org/

L earn About Bleeding Disorders How We Can Help How You Can Help Other Web Links About Your Privacy We know that protecting the information you give us is important to you. It's also important to us. Click here to see our privacy policies. This site is dedicated to providing information on the opportunities available through Hemophilia of Georgia for Georgia families who have hemophilia, von Willebrand disease, or other inherited bleeding disorders. If you or a member of your family have been diagnosed with an inherited bleeding disorder, we invite you to contact us for more information. Our History: In 1973 Georgia families came together to form a non-profit agency to serve the needs of the bleeding disorders community in Georgia. Hemophilia of Georgia continues to fulfill the mission of its founders. Guided by a volunteer Board, including individuals with bleeding disorders, H.O.G. meets each new challenge on the road to finding a cure by providing an expanding array of services. H.O.G. HOTLINKS!

26. Alex Foundation Cares for people with hemophilia and other disabilities. Includes overview, news and staff list. http://www.alex.org.ge

Vazha-Pshavela ave. 45,TBILISI,GEORGIA. Tel/Fax:(995 32) 25 28 14. Mobil: (995 99) 103 473. alexis@gol.ge sl="1.3"

27. Hemophilia "The Royal Disease" http://ublib.buffalo.edu/libraries/projects/cases/hemo.htm

28. CNN.com - Gene Therapy Successful In Treating Hemophilia B, Researchers Say - Ma CNN http://www.cnn.com/2000/HEALTH/03/01/goodgene.therapy/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Gene therapy successful in treating hemophilia B, researchers say March 1, 2000 Web posted at: 10:45 p.m. EST (0345 GMT) (CNN) Researchers at the Children's Hospital of Philadelphia and Stanford University have successfully used gene therapy to treat hemophilia B, according to a study published in this month's Nature Genetics.

29. Welcome To Hempohilia Center Of Western New York Offers a variety of services related to hemophilia and other hereditary blood disorders. http://www.wnyhemophilia.com/

Hemophilia Center of WNY, Inc. Chapter of the National Hemophilia Foundation 462 Grider Street Buffalo, NY 14215 Table Of Contents Facts about Hemophilia What We Provide Directions Email Us ... Yellow Pages Hemophilia Center of WNY Chapter of the National Hemophilia Foundation The Center is a not-for-profit, licensed diagnostic and treatment center. It offers a variety of services for persons with hemophilia and other hereditary blood disorders ensuring that the patient is cared for at all times- whether at the hospital, at home, at the Center, at school, or on the job. Hemophilia Center of WNY A Chapter of the National Hemophilia Foundation Adult Unit Erie County Medical Center 462 Grider Street 5th Floor Buffalo, New York 14215 Pediatric Unit 219 Bryant Street 3rd Floor D Bldg. Buffalo, New York 14222 Office Hours: Monday - Friday 8:30 a.m. - 4:30 p.m. 24 Hour emergency service Comprehensive clinic visits scheduled by appointment.

30. Association Of Hemophilia And Donorship Represents and advocates the interests of people with hemophilia in Georgia. Includes overview, information about hemophilia and details of current projects. http://www.gahd.org.ge

31. MedlinePlus Medical Encyclopedia: Hemophilia A hemophilia A. Definition Return to top. hemophilia A is a hereditary blood coagulation (clotting) disorder. It is caused by a deficient http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Hemophilia A Contents of this page: Illustrations Definition Causes, incidence, and risk factors Symptoms ... Prevention Illustrations Blood clots Definition Return to top Hemophilia A is a hereditary blood coagulation (clotting) disorder. It is caused by a deficient activity of plasma protein factor VIII, which affects the clotting property of blood. Causes, incidence, and risk factors Return to top Hemophilia is a hereditary bleeding disorder of specific blood clotting factors. There are several types, including hemophilia A and B. Hemophilia A is the most common of these disorders and is the result of a deficiency of clotting factor VIII. The disorder is caused by an inherited sex-linked recessive trait with the defective gene located on the X chromosome. Females carry two copies of the X chromosome, and therefore if the factor VIII gene on one chromosome is defective, the gene on the other chromosome can compensate. Males, however, carry only one X chromosome, so if the factor VIII gene on that chromosome is defective, they will have the disease. Females with one defective factor VIII gene are carriers of this trait. Fifty percent of the male offspring of female carriers have the disease and 50% of their female offspring are carriers. All female children of a male hemophiliac are carriers of the trait.

32. Cell Genesys, Inc. Focused on the development and commercialization of cancer vaccines and gene therapies to treat various cancers including leukemia, hemophilia A and B, restenosis after angioplasty and Parkinson's disease. http://www.cellgenesys.com

33. Octagen Corporation | Developing New Therapies For Hemophilia Privately held company developing therapies for hemophilia and other genetic disorders, using recombinant Factor VIII and gene therapy. Includes clinical trial status, licensing, corporate profile and contacts in Bala Cynwyd, Pennsylvania. http://www.octagen.com/

Octagen Corporation is a privately held biopharmaceutical company whose mission is to develop and commercialize improved therapies for hemophilia and other genetic disorders. Legal Notice

34. Tunnel For information in English, please go to this site Swedish hemophilia Society. http://www.xpress.se/fbis/english.html

For information in English, please go to this site: Swedish Hemophilia Society Nepal - our twinning partner This site works best with Internet Explorer. Download Explorer here

35. World Federation Of Hemophilia FAQ Information and safety issues about blood collection, hemophilia, and blood products. http://www.wfh.org/ShowDoc.asp?Rubrique=28&Document=42

36. VersaPharm Pharmaceutical developer and marketer of specialty prescription products to the United States, working to develop and deliver pharmaceuticals primarily for treatment areas of Tuberculosis, hemophilia, and other blood disorders. http://www.versapharm.com/

VersaPharm Incorporated develops and markets specialty prescription products to the United States: Pharmaceuticals for Tuberculosis, Hemophilia, Anthrax, STD, blood disorders and other diseases. By using this website, you agree to be bound by the Terms of Service and Purchase currently in effect. Click here to enter website Terms of Service If you have problems with this website, please contact the Webmaster Website design and maintenance by Photel International 043 020 011 M Date Last Updated: May 17, 2004

37. Welcome To The Canadian Hemophilia Society We have moved! The CHS web site is being updated soon. The address of the home page (www.hemophilia.ca) remains unchanged. However http://www.hemophilia.ca/en/0.0.html

We have moved! The CHS web site is being updated soon. The address of the home page (www.hemophilia.ca) remains unchanged. However, you will have to update all other Bookmarks/Favorites within the CHS site Click here to enter the new site.

38. MedlinePlus Medical Encyclopedia: Factor V Deficiency Provides brief information about this inherited bleeding disorder, which is similar to hemophilia. Includes causes, symptoms, and prognosis. http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Factor V deficiency Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Blood clot formation Blood clots Alternative names Return to top Parahemophilia; Owren's disease   Definition Return to top Factor V deficiency is an inherited abnormal blood coagulation disorder caused by a deficiency of the plasma protein Factor V.   Causes, incidence, and risk factors Return to top Normal blood coagulation is a complex process involving as many as 20 different plasma proteins , which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. Factor V deficiency is caused by inheriting a defective Factor V gene. In this disorder, bleeding ranges from mild to severe. The disease is similar to hemophilia , except bleeding into joints is less common. Bleeding can occur almost anywhere in the body, and death from hemorrhage has occurred with this disorder.

39. FAMOHIO Hemophilia Home Page Promotes the sharing of knowledge, experiences and concerns among those individuals with hemophilia and related bleeding disorders. http://www.famohio.org/

Welcome To FAMOHIO ! FAMOHIO promotes the sharing of knowledge, experiences and concerns among those individuals with hemophilia and related bleeding disorders. FAMOHIO is a registered 501(c)(3) charity. Click on the FAMOHIO logo to enter the main site or select one of the shortcuts below. Visitors To FAMOHIO Portions of the FAMOHIO web site were last updated on April 26, 2004 The next FAMOHIO annual meeting will be August 6 - 8, 2004 in Columbus, Ohio. FAMOHIO, Inc

40. LSUSU Gene Therapy Program The Gene Therapy Program is located in the Department of Medicine and affiliated with the Stanley S. Scott Cancer Center and the Center for Human and Molecular Genetics at Louisiana State University Health Sciences Center at New Orleans. The major aim of the LSUHSC Gene Therapy Program is to develop new therapies for a series of genetic and acquired diseases including Cystic Fibrosis, hemophilia, Krabbe's Disease and infectious diseases such as AIDS, TB, and pneumonia. http://www.medschool.lsumc.edu/GeneTherapy/Default.htm

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