41. EMedicine - Childhood Migraine Variants : Article Excerpt By: Wendy G Mitchell, hemiplegic migraine (usually an autosomal dominant disorder) may present in early childhood and occasionally may continue into adulthood. http://www.emedicine.com/neuro/byname/childhood-migraine-variants.htm

(advertisement) Excerpt from Childhood Migraine Variants Synonyms, Key Words, and Related Terms: abdominal migraine, acute confusional migraine, basilar migraine, benign paroxysmal vertigo of childhood, cyclic vomiting of childhood, hemiplegic migraine, migraine, migraine aura without headache, ophthalmoplegic migraine, vascular headache Please click here to view the full topic text: Childhood Migraine Variants Background: Migraine in children may be similar to adult presentations and include headache, with or without aura, accompanied by nausea, vomiting, photophobia, and relief with sleep. However, several variations of migraine are unique to children and rarely if ever occur in adults. Migraine may present with prominent nonheadache symptoms in young children (migraine without headache), or neurologic symptoms (aura) may be much more prominent than the headache. Various recognized childhood syndromes assumed to be pathophysiologically related to migraine include benign paroxysmal vertigo of childhood, abdominal migraine, cyclic vomiting of childhood, and acute confusional migraine (acute confusional state). Basilar migraine (particularly in adolescent girls) may present with prominent dizziness and near-syncope and/or syncope with or without a subsequent headache. Hemiplegic migraine (usually an autosomal dominant disorder) may present in early childhood and occasionally may continue into adulthood. Ophthalmoplegic migraine also may occur in childhood.

42. Welcome To, Sporadic hemiplegic migraine a separate entity should be classified with familial hemiplegic migraine Danish researchers compared the clinical http://www.globalfamilydoctor.com/publications/GFDnews/item701.htm

'Sporadic hemiplegic migraine' a separate entity - should be classified with familial hemiplegic migraine Danish researchers compared the clinical characteristics of patients with sporadic hemiplegic migraine with those of patients with migraine with typical aura and patients with familial hemiplegic migraine, using a computer search of Denmark's National Patient Register to screen the population for patients with migraine with aura with motor weakness. They also examined case records from headache clinics and private practicing neurologists and placed advertisements. They screened patients and their relatives with a semi-structured validated telephone interview, and then all recruited patients were interviewed by a physician and given a neurologic examination. A total of 105 patients with sporadic hemiplegic migraine were identified. The researchers found: "72% had four typical aura symptoms: visual, sensory, aphasic, and motor. All had at least two symptoms present during attacks. A gradual progression and sequential appearance of aura symptoms was typical; compared with migraine with typical aura, the duration of each aura symptom was usually prolonged and bilateral motor symptoms were more frequent. Of the patients with sporadic hemiplegic migraine, 72% fulfilled the criteria for basilar migraine during attacks. The aura was usually followed by headache, as is common in sporadic hemiplegic migraine but not migraine with typical aura."

43. Hemiplegic Migraine hemiplegic migraine. From Barbara Harper Date 12/21/2003 Time 34742 PM. Comments. In May, 2002, I started having hemiplegic migraines over the age of 55. http://www.redwingnet.com/lisastravels/_Lisabeths_Travels/0000048a.htm

Lisabeth's Travels Wing Tips Home Contents Search Post ... Previous Up hemiplegic migraine From: Barbara Harper Date: Time: 3:47:42 PM Comments Last changed: December 21, 2003

44. Hemiplegic Migraine hemiplegic migraine. From Lisabeth Date 11/10/2002 Time 104819 AM. Comments. In October, I got to see the German Krankenhouse (Hospital) from the inside. http://www.redwingnet.com/lisastravels/_Lisabeths_Travels/0000041f.htm

Lisabeth's Travels Wing Tips Home Contents Search Post ... Previous Up Hemiplegic Migraine From: Lisabeth Date: Time: 10:48:19 AM Comments Last changed: November 10, 2002

45. Karger Publishers Familial hemiplegic migraine with Cerebellar Ataxia and Paroxysmal Psychosis M. Spranger a , S. Spranger c , S. Schwab a , C. Benninger b , M. Dichgans d http://content.karger.com/ProdukteDB/produkte.asp?Doi=8039

46. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor Links about Hemiplegic American Council for Headache Education hemiplegic migraine Page List of symptoms associated with hemiplegic migraine. http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica

Match: sort by: relevance date Free Services Subscribe by email RSS newsfeeds PDA-friendly format loc="/images/" A A A Find Jobs In: Healthcare Engineering Accounting College Contract / Freelance Customer Service Diversity Engineering Executive Healthcare Hospitality Human Resources Information Tech International Manufacturing Nonprofit Retail All Jobs by Job Type All Jobs by Industry Relocating? Visit: Moving Resources Moving Companies Mortgage Information Mortgage Calculator Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Migraine Hemiplegic (3 links) News about Hemiplegic Study Finds A Mouse Model For Episodic Neurological Disorders (August 5, 2002) full story [ More news about Hemiplegic Books about Hemiplegic Amazon.com's Price: Prices subject to change. Steps to Follow: The Comprehensive Treatment of Patients with Hemiplegia by: Patricia M. Davies 15 May, 2000 Amazon.com's Price: Prices subject to change. Right in the Middle: Selective Trunk Activity in the Treatment of Adult Hemiplegia by: Patricia M. Davies July, 1990 Amazon.com's Price:

47. Familial Migraine with aura including hemiparesis and where at least one first degree relative has identical attacks.......Familial hemiplegic migraine. http://www.dent.ucla.edu/sod/depts/oralfacial/courses/merrill/hemipleg.html

Familial Hemiplegic Migraine Description: Migraine with aura including hemiparesis and where at least one first degree relative has identical attacks. Diagnostic Criteria: A. Fulfils criteria for 1.2. B. The aura includes some degree of hemiparesis and may be prolonged. C. At least one firs degree relative has identical attacks. Comments: This disorder is marked by paralysis of the limbs on one side (hemiplegia). It may be seen as a feature of the prodromal phase and resolve as the headache appears, as with migraine. The headache is usually ipsilateral to the hemiplegia. Brainstem dysfunction is commonly observed with the headache (see Basilar Migraine). This disorder probably has the same pathophysiology as migraine with typical aura. The reason for still keeping it separate is that families have been described where attacks are strikingly identical and sometimes long lasting. The term familial hemiplegic migraine has been abused since in most families different forms of migraine occur and most patients with hemiplegic attacks have these intermingled with more frequent attacks of migraine without hemiparesis. The headache occurs in both sporadic and familial forms. Usually beginning in childhood, sometimes as early as 1-2years and generally ceasing in adulthood. The hemiplegia is usually part of the aura and may last an hour or longer. Headache follows the hemiplegia or may occur with it. There is a male predominance. CSF pleocytosis may be present (predominantly PMN's). Cerebral angiography performed during the hemiparetic attacks are usually unremarkable although constriction of the internal carotic and basilar arteries have been seen.

48. RxPG : Forums : MRCP : Have You Heard Of A Hemiplegic Migraine? Have you heard of a hemiplegic migraine? PostPosted May 12, 2004, 406 pm Post subject Have you heard of a hemiplegic migraine? Reply with quote. http://www.aipge.com/postt2292.html

plab You can log in this site with a RxPG ID ! Do you have one? Get one now, click here RxPG: Forums Forum FAQ Search Usergroups Profile Log in to check your private messages Log in Have you heard of a hemiplegic migraine? RxPG Forum Index MRCP View previous topic ... View next topic Author Message sanjukta.a Newbie Joined: Apr 03, 2004 Posts: 3 Posted: May 12, 2004, 4:06 pm Post subject: Have you heard of a hemiplegic migraine? Have you heard of a hemiplegic migraine? migraine syndrome that is associated with a weakness or sensory loss of the limbs on one side of the body. The headache usually precedes the weakness by a day or more. The limbs gradually return to normal over several days. Autosomal dominant in its familial form Caused by defect in the neuronal voltage-gated calcium channel on Chromosone 19. There is oedema of the involved arteries Hope this does not come in MCQs coz its very easy to confuse it with a TIA, isint it? Back to top Display posts from previous: All Posts 1 Day 7 Days 2 Weeks 1 Month 3 Months 6 Months 1 Year Oldest First Newest First RxPG Forum Index MRCP All times are GMT - 5 Hours Page of Jump to: Select a forum Nagging Q Zone mediMOCK Nagging Q Salgunan Dental Postgraduation Dental INDIA AIPGE BHU JIPMER MAHE NIMHANS PGIMER SGPGI Alerts CMC Vel.

49. Entrez PubMed Click here to read The familial hemiplegic migraine mutation R192Q reduces Gprotein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in http://www.facultyof1000.com/pubmed/12527722

Entrez PubMed Nucleotide Protein ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes 3D Domains Domains Gene GEO GEO DataSets HomoloGene Journals MeSH NCBI Web Site OMIM PMC PopSet SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard ... Text Version Entrez PubMed Overview FAQ Tutorial New/Noteworthy ... E-Utilities PubMed Services Journals Database MeSH Database Single Citation Matcher Batch Citation Matcher ... Cubby Related Resources Order Documents NLM Gateway TOXNET Consumer Health ... PubMed Central Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links HomoloGene Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links Show: Sort Author Journal Pub Date Text File Clipboard E-mail Order J Physiol. 2003 Jan 15;546(Pt 2):337-47. Related Articles, Links The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. Melliti K, Grabner M, Seabrook GR.

50. :: Ez2Find :: Hemiplegic American Council for Headache Education hemiplegic migraine Page Site Info - Translate - Open New Window List of symptoms associated with hemiplegic http://ez2find.com/cgi-bin/directory/meta/search.pl/Health/Conditions_and_Diseas

Guide : Hemiplegic Global Metasearch Any Language English Afrikaans Arabic Bahasa Melayu Belarusian Bulgarian Catala Chinese Simplified Chinese Traditional Cymraeg Czech Dansk Deutsch Eesti Espanol Euskara Faroese Francais Frysk Galego Greek Hebrew Hrvatski Indonesia Islenska Italiano Japanese Korean Latvian Lietuviu Lingua Latina Magyar Netherlands Norsk Polska Portugues Romana Russian Shqip Slovensko Slovensky Srpski Suomi Svenska Thai Turkce Ukrainian Vietnamese Mode All Words Any Word Phrase Results Timeout Depth Adult Filter Add to Favorites Other Search Web News Newsgroups Images Guides Hemiplegic ez2Find Home Directory Health Conditions and Diseases ... Migraine : Hemiplegic Web Sites American Council for Headache Education Hemiplegic Migraine Page [Site Info] [Translate] [Open New Window] List of symptoms associated with hemiplegic migraine. URL: http://www.achenet.org/kids/hemi.php Migraine Gene Discovered [Site Info] [Translate] [Open New Window] Article discusses rare form of hemiplegic migraine linked to gene on chromosome 19. URL: http://www.pnl.gov/er_news/12_96/migraine.htm National Headache Foundation [Site Info] [Translate] [Open New Window] Brief description of the condition.

51. Botulinum Toxin Type A In The Treatment Of Sporadic Hemiplegic Migraine Botulinum Toxin Type A in the treatment of sporadic hemiplegic migraine A case report. A neurologist diagnosed sporadic hemiplegic migraine. http://www.priory.com/psych/Botulinum.htm

Botulinum Toxin Type A in the treatment of sporadic hemiplegic migraine: A case report. Authors and correspondence: Principle author and correspondence: Dr. Ray Goggins, Specialist Registrar in General Adult Psychiatry, Cirencester Memorial Centre, Sheep St, Cirencester, Gloucestershire, GL7 1QR raygoggins@yahoo.co.uk Telephone: +44 (01285) 640933 or +44 (07941) 865178 Fax: ++44 (0117) 9241750 Dr Daniel Rogers, Consultant Neuropsychiatrist, the Burden Centre, Bristol, BS16 1JB Telephone (0117) 9186710 Abstract Recent reports suggest that Botulinum toxin type A may help patients suffering from chronic pain disorders. We report a unique case of a 47 year old woman with hemiplegic migraine responding to botulinum toxin type A injections. There is increasing evidence that botulinum toxin type A may be a useful treatment for severe headaches and migraines. To our knowledge this is the first case report of its successful use in sporadic hemiplegic migraine. Case report A 44 year old woman was referred to a tertiary neuropsychiatric centre by her GP with disabling headaches. At the age of 41 she developed episodes of severe headache for the first time which gradually increased in severity. There was no family history of migraine. Episodes would start with nausea for 30 to 60 minutes followed by a pain in her forehead which could be right or left sided and occasionally bilateral and which spread gradually to the back of her head and down her neck. She also had mild photophobia, phonophobia and prostration. She often would notice "a cloudy film" over her vision but no classic migrainous visual disturbances. She described headaches as "horrendous" like "a tightening band" around her head. They occurred at any time of the day but often were present when she awakened. Simple analgesics were largely ineffective in reducing the pain.

52. Familial Hemiplegic Migraines To be termed a familial hemiplegic migraine, the sufferer must have symptoms of hemiparesis or a pins and needles feeling on one side or limb of the body. http://www.msu.edu/user/espino11/familia.htm

Familial hemiplegic migraines Familial hemiplegic migraines are associated with severe headache pain and a gradual onset of unilateral weakness or heaviness. To be termed a familial hemiplegic migraine, the sufferer must have symptoms of hemiparesis or a pins and needles feeling on one side or limb of the body. This type of migraine could completely resolve in minutes or last several hours, but the hemiparises will last hours or days beyond the headache itself. It is also very typical that the hemiparesis may being evfen before the headache attack. A complicated hemiplegic attack also occurs, where the weakness may last up to two weeks or may never resolve entirely. A familial hemiplegic migraine is ususally inherited from the mother and the affected side of the body in most instances is associated with dysphasia and other cortical symtoms. Becuase of ischaemic changes in the cerebrum and brainstem, deaths due to familial hemiplegic migraines have been recorded. Back to Main Page

53. The Migraine Gene The Migraine Gene. Overview. The familial hemiplegic migraine, FHM, a subtype of migraine with aura, has been mapped to chromosome 19p13. http://www.msu.edu/user/espino11/genetics.htm

The Migraine Gene Overview The familial hemiplegic migraine, FHM, a subtype of migraine with aura, has been mapped to chromosome 19p13. Diagram of the gene where chromosome 19p13 is found Brain-secifif P/Q-type calcium-channel alpha -subunit gene, CACNA1A is identified in the responsible region of 47 exons covering 300 kb. The familial hemiplegic migraine is the result of a missense mutation in the alpha subunit. In the sequencing of all the exons and their corresponding surroundings, a polymorphic variation is revealed, including a (CA) n -repeat and a (CAG) n -repeat in the 3' untranslated region. In the familial hemiplegic migraine, four missense mutations were discovered in conserved functional domains and one of the mutations has occurred in two different unrelated families of hemiplegic migraines. FHM is a rare autosomal dominant subtype migraine with aura and is associated within some families with progressive cerebellar atrophy and ictal hemiparesis. The cerebellar atrophy was found in FHM is linked to the chromosome 19p13. The region that contains chromosome 19p13 FHM locus is also involved with migraines with or without auras. This adds to the hypothesis that FHM is part of the migraine spectrum involving biological mechanisms and similar genetic factors. Mutations In FHM, several synonymous nucleotide substitutions and polymorphisms were identified by their occurrence in lack of cosegregation with the disease and in unaffected controls. The

54. CACNA1A Reference. CM960237, 192, CGGCAG, Arg-Gln, hemiplegic migraine and episodic ataxia 2, 1. CM012333, 195, AGG-AAG, Arg-Lys, hemiplegic migraine, 2. http://archive.uwcm.ac.uk/uwcm/mg/ns/1/126432.html

Nucleotide substitutions (missense / nonsense) Accession Number Codon Nucleotide Amino acid Phenotype Reference CGG-CAG Arg-Gln Hemiplegic migraine and episodic ataxia 2 AGG-AAG Arg-Lys Hemiplegic migraine tCAT-TAT His-Tyr Episodic ataxia 2 aGGG-AGG Gly-Arg Spinocerebellar ataxia 6 CGA-CAA Arg-Gln Hemiplegic migraine and ataxia ACG-ATG Thr-Met Hemiplegic migraine and episodic ataxia 2 GTG-GCG Val-Ala Hemiplegic migraine and episodic ataxia 2 GACa-GAG Asp-Glu Hemiplegic migraine, progressive cerebellar ataxia gCGA-TGA Arg-Term Episodic ataxia cAAA-GAA Lys-Glu Hemiplegic migraine TAC-TGC Tyr-Cys Hemiplegic migraine, coma, cerebellar atrophy TTC-TGC Phe-Cys Episodic ataxia 2 cGTG-TTG Val-Leu Hemiplegic migraine TTC-TCC Phe-Ser Episodic ataxia 2 cCGA-TGA Arg-Term Episodic ataxia 2 CGC-CAC Arg-His Episodic ataxia 2 cCGG-TGG Arg-Trp Hemiplegic migraine with cerebellar signs cTGG-CGG Trp-Arg Hemiplegic migraine with cerebellar signs tGTC-ATC Val-Ile Hemiplegic migraine gGAA-AAA Glu-Lys Episodic ataxia 2 cATC-CTC Ile-Leu Hemiplegic migraine and episodic ataxia 2 cCGA-TGA Arg-Term Episodic ataxia TACa-TAG Tyr-Term Hemiplegic migraine and ataxia References 1 - Ophoff (1996) Cell 2 - Ducros (2001) N Engl J Med ... Dev Med Child Neurol HGMD

55. Karyn S. Huntting's Basilar Artery Migraine (BAM) Page > BAM And Migraine Varian vascular insufficiency. The other forms of migraine variant are (1) retinal migraine, (2) opthalmoplegic migraine, (3) hemiplegic migraine, (4) facial migraine http://s-2000.com/bam/bam_variants.html

The BAM Page Home All About BAM: "The Online Basilar Artery Migraine Book" About The BAM Page Endorsements and Links What Patients Say BAM Page Awards BAM Page FAQ What's New Guestbook ... Medical Research Studies In Patients' Own Words Free MEDLINE Access Resources BAM Discussion Forum Worldwide BAM Community BAM Patient Journals Physician Referrals Link to The BAM Page How You Can Help Miscellaneous Fun Stuff Activities ... Links BAM and Migraine Variants Though BAM is a migraine variant, and therefore technically belongs under the classification of "migraine," a BAM attack can also represent a form of "acute cerebral vascular insufficiency." The other forms of migraine variant are (1) retinal migraine, (2) opthalmoplegic migraine, (3) hemiplegic migraine, (4) facial migraine, and (5) migrainous infarction. Of these, only hemiplegic migraine has been found to be a dominant characteristic in terms of heritability in families. Hemiplegic migraine is also the only form of migraine for which a gene has been located. It is a gene located on chromosome 19 that carries the trait for hemiplegic migraine. Hemiplegia can develop either before or during a migraine. Though Basilar Artery Migraine is certainly a distinct form of migraine variant, BAM patients can exhibit the signs of hemiplegic migraine.

56. Forum2000 Click Here. hemiplegic migraine. Forum2000 Basilar Artery Migraine BAM Forum and Guestbook INACTIVE TOPICS (Moved to NEW Forum2000) hemiplegic migraine http://s-2000.com/forum/messages/4/224.html?907194121

57. Neurological Disorders, Headaches, Migraine, Hemiplegic Click here for more information. American Council for Headache Education hemiplegic migraine Page List of symptoms associated with hemiplegic migraine. http://www.iseekhealth.com/hemiplegic-2041.php

Home About Us Contact Submit Your Site Search : Home Health Conditions and Diseases Neurological Disorders ... Hemiplegic More Hemiplegic Categories: Submit Your Site to the Hemiplegic category Sponsored Hemiplegic Sites Order Prescription Drugs Online No prior prescription required for Fioricet, Ambien, Phentermine, Levitra, Tramadol, Soma, Prozac and many other prescription drugs. U.S. Pharmacists and Physicians. FEDEX Delivery using Credit Card, Money Order and check. Eliminate Your Headache and Migraine Do you want your headache and migraine pain to vanish? Fioricet (butalbital) is the pain pill for you. Very low prices on this miracle pill. Free shipping. Lowest Cost Fioricet Butalbitial Get It FAST! Order your Fioricet Butalbitial today VERY Cheap get it FAST! Generic or Brand Fioricet. Secure Ordering. PRIVATE, Discreet packaging, Shipping Daily. USA Only. TMJ / TMD Symptom ReliefNeuromuscular Dentistry Neuromuscular dentistry can help relieve your TMJ / TMD related symptoms including tinnitus, jaw pain, and headaches / migraines. Click here for more information. The NEW Super Blue From Blue Stuff Inc.

58. 2552: Linkage Analysis Of Hemiplegic Migraine Loci And ChrXq28 In 29 Families Wi Program Nr 2552 Linkage analysis of hemiplegic migraine loci and ChrXq28 in 29 families with familial migraine. P. van Galen 1 http://www.faseb.org/genetics/ashg99/f2552.htm

Program Nr: 2552 Linkage analysis of hemiplegic migraine loci and ChrXq28 in 29 families with familial migraine. P. van Galen , K. Gardner , J. Pascual , M. Barmada , J. Badger , M. Soso , E. Hoffman 1) Department of Human Genetics, University of Pittsburgh, PA; 2) Department of Neurology, University Hospital Marques de Valdecilla Santander, Spain; 3) Department of Neurology, University of Pittsburgh, Pittsburgh, PA; 4) Children's National Medical Center,Washington, DC.

59. Hemiplegic NEJM The Clinical Spectrum of Familial hemiplegic migraine Associated with Mutations in a Neuronal Calcium Channel Original Article from The New England http://www.facesinterquest.com/pharmacy/pharmacy/hemiplegic.php

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60. Echocardiography Pfaffenrath V, Pollmann W, Autenrieth G, Rosmanith U. Mitral valve prolapse and platelet aggregation in patients with hemiplegic and nonhemiplegic migraine. http://www2.umdnj.edu/~shindler/migraine.html

Migraine and Echocardiography E-chocardiography Journal: Alphabetical List Chronological List Images Home Page The migraine patient may present with aura without headache, occasionally mimicking a transient ischemic attack. The unilateral sensory loss, hemiparesis, or dysphasia may prompt referral to echocardiography to rule out a cardiac source of embolus. Migraine by B. Todd Troost, M.D. Diagnosis and Treatment of Headaches in Office Practice by David C. Haas, M.D. Frequent questions: American Council for Headache Education (ACHE) St. Anthony's Fire. A historical account of an ancient disease and it's relationship to the modern treatment of migraine. The following references discuss a possible pathophysiological relationship between migraine and mitral valve prolapse: Herman P. Migraine and mitral valve prolapse. Archives of Neurology 46(11):1165, 1989 Nov. Herman P. Migraine, large pupils, mitral valve prolapse and emotional disturbances: an autonomic disorder. Headache 27(6):340-4, 1987 Jun. Pfaffenrath V, Pollmann W, Autenrieth G, Rosmanith U. Mitral valve prolapse and platelet aggregation in patients with hemiplegic and non-hemiplegic migraine.

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