1. NGDF: Frequently Asked Questions About Graves Disease National graves disease Foundation overview of this condition. http://www.ngdf.org/faq.htm

National Graves' Disease Foundation Frequently Asked Questions About Graves' Disease What is Graves' Disease? The leading cause of hyperthyroidism, Graves' disease represents a basic defect in the immune system, causing production of immunoglobulins (antibodies) which stimulate and attack the thyroid gland, causing growth of the gland and overproduction of thyroid hormone. Similar antibodies may also attack the tissues in the eye muscles and in the pretibial skin (the skin on the front of the lower leg). Facts Graves' disease occurs in less that 1/4 of 1% of the population. Graves' disease is more prevalent among females than males. Graves' disease usually occurs in middle age, but also occurs in children and adolescents. Graves' disease is not curable, but is a completely treatable disease Symptoms Fatigue Weight Loss Restlessness Tachycardia (rapid heart beat) Changes in libido (sex drive) Muscle weakness Heat intolerance Tremors Enlarged thyroid gland Heart palpitations Increased sweating Blurred or double vision Eye complaints, such as redness and swelling

2. Welcome To The National Graves Disease Foundation National Graves Disease Foundation PO Box 1969, Brevard, NC 28712. National Graves Disease Foundation Guest Book. Sign Our Guestbook. http://www.ngdf.org/

[Order "Graves' Disease, In Our Own Words"] National Graves' Disease Foundation P.O. Box 1969, Brevard, NC 28712 A nonprofit, educational organization American Association of Clinical Endocrinologists American Thyroid Association Thyroid Foundation of America Endocrine Nurses’ Society ThyCa: Thyroid Cancer Survivors’ Association National Graves’ Disease Foundation Light of Life Foundation Invite you to a Forum with Thyroid Experts: Thyroid Disease and You A FREE Public Awareness Educational Forum Concerned about low energy? memory loss? ... fatigue? depression rapid heart beat restlessness infertility ... weight or hair changes a lump on your neck? Could it be your thyroid? What if it’s not your thyroid? Thursday, April 29, 2004 7:00 p.m. – 9:00 p.m. Hynes Convention Center Meeting Room 100 Boston, Massachusetts Information for the 2004 Bridge to Wellness XII, Oct 22-24 2004 Click here for the NGDF Fundraiser 50% of the proceeds go to the NGDF Did you know... 13 million Americans have a thyroid disorder and more than half of them are not aware of it.

3. Graves' Disease Search our database by Health Topic or enter your own keywords. GRAVES' DISEASE. What is graves disease? What is an autoimmune disease? What are the symptoms of Graves' Disease? How do I know if I have this disease? http://www.4woman.gov/faq/graves.htm

Search our database by Health Topic or enter your own keywords GRAVES' DISEASE What is an autoimmune disease? What are the symptoms of Graves' Disease? How do I know if I have this disease? What is the treatment for this disease? ... What could happen if this disease is left untreated? See also . . . Autoimmune Diseases Thyroid Disease Graves' Disease is a type of autoimmune disease in which the immune system over stimulates the thyroid gland, causing hyperthyroidism . Over-activity of the thyroid gland is also sometimes called "diffuse toxic goiter." The thyroid gland helps set the rate of metabolism (the rate at which the body uses energy), and when it is over-stimulated, it produces more thyroid hormones than the body needs. High levels of thyroid hormones can cause difficult side effects. This is an extremely rare disease that tends to affect women over the age of 20. The incidence is about 5 in 10,000 people. What is an autoimmune disease? An autoimmune disease occurs when the body's immune system becomes misdirected and attacks the very organs, cells, or tissues that it was designed to protect. About 75% of autoimmune diseases occur in women, most frequently during their childbearing years. What are the symptoms of Graves' Disease?

4. Graves'Disease MEDSTUDENTS-ENDOCRINOLOGY A review of the key concepts of management of Graves’ disease (hyperthyroidism), including definition, etiology, prevalence, incidence, pathology and http://www.medstudents.com.br/endoc/endoc5.htm

ENDOCRINOLOGY MARCELO SPECTOR Medstudents' Homepage Graves'Disease Part 1 Hyperthyroidism and Thyrotoxicosis Thyrotoxicosis are the clinical, physiologic and biochemical syndromes that result when tissues are exposed to, and respond to high levels of thyroid hormone. In most instances, thyrotoxicosis is due to hyperactivity of thyroid gland, or hyperthyroidism (hypermetabolism). Occasionally, thyrotoxicosis may be due to other causes such as excessive ingestion of thyroid hormone or secretion form ectopic sites. There are various forms of thyrotoxicosis and the most common is Graves’ Disease. Definition Graves’ disease, also known as Parry’s or Basedow’s disease or diffuse toxic goiter, is a disorder with three major manifestations: hyperthyroidism with diffuse goiter, ophthalmopathy, and dermopathy. They do not appear together. Indeed, one or two need never appear, and moreover, the three may run courses that are largely independent of one another. Prevalence It is the most common form of thyrotoxicosis. It affects as many as 1.9 per cent of the female population. The ratio of women to men is as high as 7:1. It reaches its peak incidence between the third and forth decades and the reason for the female predominance in this as in all thyroid diseases is unknown. Genetic factors play an important role, since there is an increased frequency haplotypes HLA-B8 and -DRw3 in Caucasian, HLA-Bw36 in Japanese, and HLA-Bw46 in Chinese patients with the disease. Etiology and Pathogenesis Graves’ disease is currently viewed as an autoimmune disease of unknown cause. Hyperthyroidism is its principal manifestation, yet TSH is suppressed and no intrinsic abnormalities in the gland have been identified.

5. EMedicine - Graves Disease : Article By Lynne Lipton Levitsky, MD graves disease graves disease is the most common cause of hyperthyroidism in children. It is an immune-mediated disorder resulting from the production of thyroid-stimulating immunoglobulins (TSI http://www.emedicine.com/ped/topic899.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Endocrinology Graves Disease Last Updated: January 17, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: hyperthyroidism, thyrotoxicosis, von Basedow disease, Graves’ disease, thyroid-stimulating immunoglobulin, TSI, thyroxine, T4, triiodothyronine, T3 AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Lynne Lipton Levitsky, MD , Chief, Pediatric Endocrine Unit, Massachusetts General Hospital; Associate Professor, Department of Pediatrics, Harvard University Medical School Lynne Lipton Levitsky, MD, is a member of the following medical societies: Alpha Omega Alpha American Academy of Pediatrics American Diabetes Association American Pediatric Society ... Lawson-Wilkins Pediatric Endocrine Society , and Society for Pediatric Research Editor(s): Thomas A Wilson, MD

6. Hardin MD : Graves Disease & Hyperthyroidism From the University of Iowa, the *best* lists of Internet sources in Grave's Disease Hyperthyroid. graves disease, hyperthyroid signs symptoms, graves disease pictures, graves diease, hyperthroid, hyperthroidism http://www.lib.uiowa.edu/hardin/md/gravesdisease.html

"We list the best sites that list the sites" Site Map Diseases Home Free Articles in PubMed Search Hardin MD See also: Home Endocrine Dis Thyroid Disease All links on this page hand-checked Popular Women's Health Dermatology Nursing Pharm Infect Disease AIDS +Pictures Addisons Disease +Pictures Autoimmune Diseases Eye Diseases +Pictures Fibromyalgia +Pictures Glaucoma +Pictures Goiter +Pictures Hashimotos Disease +Pictures High Blood Pressure +Pictures Hypothyroidism +Pictures Jaundice Pictures Lupus +Pictures Medical Pictures Skin Pictures Thyroid Disease ... Yeast Infection +Pictures Graves Disease Pictures Graves Disease Symptoms Open Directory Project : Hyperthyroid (Other versions: Google AOL Hyperthyroid : Graves' disease (Other versions: Google AOL HONselect : Hyperthyroidism Health on the Net Foundation, Geneva, Switzerland LookSmart : Graves' disease or hyperthroidism OMNI : Hyperthyroidism Univ Nottingham, United Kingdom Grave's disease Hyperthyroidism US Government ClinicalTrials.gov : Hyperthyroidism National Library of Medicine, National Institutes of Health

7. GRAVES DISEASE AND RAI Support board for people with this condition to help each other. Most participants have had radioactive iodine treatment. Includes background information, personal stories, and links to related sites. http://groups.msn.com/GRAVESDISEASEANDRAI/

var nEditorialCatId = 96; MSN Home My MSN Hotmail Shopping ... Money Web Search: document.write(''); Groups Groups Home My Groups Language ... Help GRAVES DISEASE AND RAI GRAVESDISEASEANDRAI@groups.msn.com What's New Join Now Helpful Hints for posting Helpful hint to track messages ... Tools Posted by Pat- The list Owner: Posting through E-MAIL We recommend that you do not use the feature to receive posts in your inbox. The managers of this group cannot change or view your e-mail settings for you. You will find a link to your e-mail settings in two places, on the toolbar on the left side of the page under "Member Tool's" and in a box on the What's New page for Member Tool's. The link to "My E-mail Settings” takes you to a page where you have the option to change your e-mail address, have it visible to the group or hidden, and "send messages to your inbox immediately" or "read on the web". Again, we recommend that you select the option to read on the web. Please understand that if you choose the option to have messages sent to your inbox the following things may happen. You may stop getting e-mail from the group at any time with no apparent reason or fix for the problem.

8. What Is Graves Disease? What is graves disease?graves disease, a type of hyperthyroidism, is caused by a generalized overactivity of. the entire thyroid gland. It is named for. Robert Graves, an Irish physician, who. was the first to describe this form of are the symptoms of Gravesdisease?. HyperthyroidismThe hyperthyroid symptoms of Gravesdisease are http://www.thyroid.org/patients/brochures/Graves_brochure.pdf

9. Index Of /Heartland/8916 Ohio woman blends cooking with Christianity and mixes crafts with computers. Special focus on graves disease and other thyroid problems and Down Syndrome. http://www.geocities.com/Heartland/8916/

Index of /Heartland/8916 Name Last modified Size Description ... Parent Directory 08-May-2004 15:12 -

10. Pretibial Myxedema From The Doctor's Doctor, description of pretibial myxedema, a dermatology complication sometimes found in graves disease. http://www.thedoctorsdoctor.com/diseases/pretibial_myxedema.htm

Background This is an uncommon complication of Grave's disease, occurring in 1-4% of patients. There is a diffuse, non-pitting edema and thickening of the skin usually on the anterior aspect of the lower legs spreading to the dorsum of the feet. Advanced cases may involve the upper trunk, upper extremities, face, neck, and ears. The lesions resolve very slowly. It occasionally occurs in non-thyrotoxic Grave's disease, autoimmune thyroiditis, and stasis dermatitis. The serum contains circulating factors which stimulate fibroblasts to increase synthesis of glycosaminoglycans. Biopsy of the skin reveals mucin in the mid to lower dermis. There is no increase in fibroblasts. With time, there may be secondary hyperkeratosis which may become verruciform. Many of these patients may also have co-existing stasis dermatitis. Elastic stains will reveal a reduction in elastic tissue. PATHOGENESIS CHARACTERIZATION TSH and TSH receptor antibody-binding sites in fibroblasts of pretibial myxedema are related to the extracellular domain of entire TSH receptor. Chang TC, Wu SL, Hsiao YL, Kuo ST, Chien LF, Kuo YF, Change CC, Chang TJ.

11. EMedicine - Graves Disease : Article By Sai-Ching Jim Yeung, MD, PhD graves disease graves disease, named after Robert J. Graves, MD, circa 1830s, is an autoimmune disease characterized by hyperthyroidism due to circulating http://www.emedicine.com/med/topic929.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Endocrinology Graves Disease Last Updated: January 30, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: diffuse toxic goiter, thyrotoxicosis, hyperthyroidism, Basedow's disease AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Sai-Ching Jim Yeung, MD, PhD , Assistant Professor, Department of Internal Medicine Specialties, University of Texas MD Anderson Cancer Center Coauthor(s): Alice Cua Chiu, MD , Consulting Staff, Department of Internal Medicine, Division of Endocrinology, Columbia Bayshore Medical Center Sai-Ching Jim Yeung, MD, PhD, is a member of the following medical societies: American College of Physicians American Medical Association American Thyroid Association , and Endocrine Society Editor(s): Steven R Gambert, MD

12. THE MERCK MANUAL, Sec. 2, Ch. 8, Thyroid Disorders The Merck Manual An in depth look at this disease including its symptoms, diagnosis treatment and graves disease. http://www.merck.com/pubs/mmanual/section2/chapter8/8d.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 2. Endocrine And Metabolic Disorders Chapter 8. Thyroid Disorders Topics [General] Euthyroid Goiter Euthyroid Sick Syndrome Hyperthyroidism ... Thyroid Cancers Hyperthyroidism (Thyrotoxicosis) A clinical condition encompassing several specific diseases, characterized by hypermetabolism and elevated serum levels of free thyroid hormones. Some controversy continues over use of the terms hyperthyroidism and thyrotoxicosis. Some authorities prefer to use thyrotoxicosis as the clinical condition that includes hyperthyroidism (then defined as the increased synthesis and secretion of thyroid hormone) as one cause. In this chapter, hyperthyroidism is used synonymously with thyrotoxicosis. Etiology Hyperthyroidism may be the result of increased synthesis and secretion of thyroid hormones (T and T ) from the thyroid gland, caused by thyroid gland stimulators in the blood or autonomous thyroid hyperfunction. It can also be caused by excessive release of thyroid hormone from the thyroid gland into the peripheral circulation without increased synthesis of the hormones. This is commonly caused by destructive changes in the thyroid secondary to the various causes of thyroiditis. The last major cause of hyperthyroidism is the conscious or accidental ingestion of excess quantities of thyroid hormone, termed thyrotoxicosis factitia. The causes of hyperthyroidism can be considered based on the thyroid radioactive iodine uptake and the presence or absence of circulating thyroid stimulators (see

13. Health And Medical Information: Diseases And Conditions, Medical Dictionary, Pro of this disease, factors that trigger the onset and current treatments....... http://www.focusonthyroid.com/Script/Main/art.asp?li=MNI&articlekey=3634

14. Graves Disease Friends with Graves. Elaine. Elaine is the author of graves disease, A Practical Guide. Reading List. graves disease A practical Guide By Elaine Moore. http://valkyrie.aarg.net/

Friends with Graves Elaine Elaine is the author of Graves Disease, A Practical Guide. Elaine also has regular articles published at Suite 101 Pam Pam is a faithful contributor to the support group at Yahoo! Groups here is another great group at the Mediboard Network. Reading List Graves Disease: A practical Guide By: Elaine Moore The Thyroid Solution By Dr. Ridha Arem Buddhism Without Beliefs: A Contemporary Guide to Awakening By: Stephen Batchelor Useful Resources Mary's Shomon's Thyroid site on about.com Amercian Autoimmune Related Diseases Association" Elaine's column at Suite 101 Welcome to my new site, it has a better look and I have finally been able (mentally etc.) to face the work of the overhaul. I haven't got my personal Graves Disease Journal up here yet, but I am working on getting that back as well. To read the old site and my journal go here This site is meant to be a gateway. There is SO MUCH information about Graves Disease and I can not put it all here. I am just hoping to provide a place to start. One thing is, if you have been diagnosed, your best weapon is reading, reading and more reading! Any knowledge that you can gather about how this disease works and how to treat will help you in the long run. The doctors that generally treat Graves are called Endocrinologists. Many times they specialize in Diabetes, so they may not have all the newest information about Graves. This disease is not simple and it may be up to you to help educate your Doctor so you can receive the best treatment possible. This disease (and many others I'm sure) require that you be proactive in the healing process.

15. Graves Disease Grave sdisease. Disease TypeAutoimmune Disease SubType Organ-specific Underlying effects. In a normal person the Thyroid system http://www.diseasedir.org.uk/disorder/dis01.htm

Grave'sdisease Disease Type: Autoimmune Disease Sub-Type: Organ-specific Underlying effects In a normal person the Thyroid system behaves as in the diagram on the left, Thyroid Stimulating Hormone (TSH) is released by the Pituitary gland into the blood stream. When this Hormone comes into contact with the a Thyroid gland cell, it attaches to a TSH receptor on the surface of the cell, which sends signals into the cell to begin releasing Thyroid hormones. The Thyroid hormones will then form a negative feedback system, ie. when the Thyroid hormones are at a high concentration it inhibits the pituitary glands production of TSH. If the concentration of Thyroid Hormone is low then the pituitary gland will release TSH, and increase the levels of Thyroid hormone as a result. In a sufferer of Grave's disease the System works the same, except an Autoimmune Antibody acts like a TSH molecule. The Antibody attaches to the Cell, and stimulates the production of Thyroid Hormones as if the Antibody was TSH itself. However, because the production of Autoimmune Antibody is independent of the Pituitary gland the -ve feedback system has no effect. Antibody will continue to be produced, and Thyroid hormones will be continually released, causing physiological damage. Aetiology Unknown, but may involve some of these factors:

16. Exophthalmos In Graves Disease, Treatment Of Thyroid Eye Disease, Naturopathy Tr An article outlining treatment of exophthalmos in graves disease through naturopathy, supported by acupuncture, acupressure and magnetic treatment in addition to eyecare and eye balls exercises. http://tedcure.com

Contact/Address pd@tedcure.com Phone Dr. P. D. Gupta. MD (Alternative Medicine) 1-2, Friends Colony, Near Jagadhri Gate Ambala City. - 134003 ( State Haryana ) I N D I A . S OME TED C ASES T REATED - O F A LL T F ORMS (photographs showing the degree of Improvement during treatment) T REATMENT O F T HYROID E YE D ISEASE - TED I NFORMATION F OR TED T REATMENT T REATMENT O F P ROBLEMS A FTER G RAVES D ISEASE :- K D EPLETION I MPAIRED C IRCULATION K NOW A BOUT TED ( salient features only ) D ECISIVE R EMEDIAL R ESULTS I N TED ( inference by some of repute ) L UNGS A LLERGY C URE C URE S OME O THER D ISEASES : V ISION - L OSS ( B LINDNESS ) D UE T O R ETINAL D ETACHMENT F ULTY B LOOD F LOW Offer : AT THE MOMENT , I render my services from Ambala City in India only, and do not have any

17. Mike's Grave's Disease Page proper use and function of this topical relief for dry eyes and highlights special considerations) Ask Dr Stoll 1997 graves disease post archive Atomic Women http://webhome.idirect.com/~wolfnowl/thyroid.htm

Mike's Grave Disease Page Greetings, and welcome. This page contains some information concerning Grave's Disease, and alternative methods of treatment. Grave's Disease is very serious, and should never be treated lightly. I have included a layman's description of the thyroid, Grave's Disease, and allopathic treatments. There are a couple of articles from the Journal of Naturopathic Medicine which explain this in more specific terms, and may be of use to a naturopathic doctor treating a patient with Grave's. There are also descriptions of some of the herbs associated with Grave's Disease. Using herbal remedies properly is a complex subject, and specific to each patient. I do not advocate persons attempting to self-treat themselves. What I would suggest is that people copy this information and use it to work with their naturopathic doctor or medical herbalist to heal themselves. At the bottom of this page are some links for sites relating to Grave's disease and thyroid disorders. A long time ago the daughter of a friend of mine developed rheumatic fever and it had complications affecting her heart, etc. Her mother tried to ask some questions of the specialist, and his attitude was "I'm the specialist; who do you think you are to be asking ME questions?" In my opinion, if you come across a doctor like that, leave. Ask a LOT of questions, and keep asking until you get the answers you need. Don't take 'NO' for an answer. The doctor may be a very competent, knowledgeable person, but at the end of the day s/he goes home and this affects your future, health, and life. Don't be rushed into anything.

18. Graves Disease In depth patient information site on Graves Eye Disease , Infiltrative Thyroid Ophthalmopathy . graves disease, hyroid optic neuropathy, orbital decompression, Antithyroid drugs, Radioactive Iodine, http://www.avclinic.com/graves_disease.htm

Angeles Vision Clinic The web site has detailed information on many other eye conditions. Please feel free to visit our Home Page or check out other eye conditions on our Eye Conditions page GRAVES EYE DISEASE OR Infiltrative Thyroid Ophthalmopathy Janet's page Hyperthyroidism is a condition in which the thyroid gland produces a greater than normal amount of hormone. It occurs in a number of diseases, including Graves' disease, toxic goitre, thyroiditis and ingestion of excessive amounts of thyroid hormones. Excessive levels of thyroid hormones give rise to weight loss, rapid hart, tremor, sweating and changes in the nails, skin and hair. Subjectively, a person will notice nervousness, heat intolerance and hart palpitations. Prominent eyes or Proptosis Inability to close eyes Graves' disease is a term used to describe the commonest variety of hyperthyroidism, which is regarded as having an autoimmune basis. Autoimmune disease may be understood as a process by which the body sees some part of itself as being foreign and reacts to it much the same way that it would with any bacteria or virus. In the case of Graves' disease, the body sees the thyroid gland as the foreign object and produces antibodies that attack the thyroid gland. This will often (but not in all cases) cause the thyroid gland to become over active. Graves' eye disease is currently believed to be due to a similar autoimmune reaction. However, in the case of

19. Graves' Disease - Information / Diagnosis / Treatment / Prevention of this disease, factors that trigger the onset and current treatments....... Graves Disease. Focus on Thyroid Medical Dictionary - graves disease http://www.healthcyclopedia.com/endocrine-disorders/thyroid/hyperthyroid/graves'

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... hyperthyroid > graves' disease Graves' Disease Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Related Topics Medical Definition Health Portals Health News ... Web Directory: Related Topics: Endocrine Disorders/Thyroid/Goiter Eye Disorders Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "graves' disease" Health Portals: MayoClinic.com Health News: Search millions of published articles for news on Graves' Disease Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Abbott Laboratories: Graves' Disease Symptoms, classic clinical signs and diagnostics of Graves' disease. Cigarette Smoking and Thyroid Eye Disease The association between cigarette smoking and ocular diseases such as Graves' Ophthamopathy. From the Hong Kong Medical Journal.

20. Graves Disease / Family Village Library graves disease. National graves disease Foundation (NGDF) PO Box 1969 Brevard, NC 28712 (704) 8775251 Email jake@ngdf.org Websitehttp//www.ngdf.org/. http://www.familyvillage.wisc.edu/lib_grav.htm

Graves Disease Who to Contact Where to Go to Chat with Others Learn More About It Web Sites ... Search Google for "Graves Disease" Who to Contact National Graves Disease Foundation (NGDF) P.O. Box 1969 Brevard, NC 28712 Email: jake@ngdf.org Website: http://www.ngdf.org/ Established in 1990, the National Graves' Disease Foundation is the only national, lay, nonprofit, educational organization open exclusively to people with Graves' disease, their families, friends and health care professionals. The NGDF offers a multi-disciplinary approach to a complex problem. Representatives of all related disciplines are included on the Medical and Advisory board: Endocrinology, Surgery, Nursing, Opthalmology, Dermatology, Psychiatry, Psychology, Pharmacology, Internal Medicine, Family Practice and Graves' disease patients. The National Graves' Disease Foundation is dedicated to increasing the public awareness of the disease and providing support and information to people with the illness. Where to Go to Chat with Others Graves Disease Web Board Graves Support This list is for people with Graves' Disease and their family and friends who are interesting in supporting them. Topics for discussion can include problems people are experiencing, their chosen course of treatment, current medical studies and possible alternative methods of treatment. This list is not intended to replace expert medical advice and treatment, but to allow folks to discuss various aspects of Graves' with others.

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