81. Targeting Hard-to-Kill Fungal Infections Targeting Hardto-Kill fungal infections Posted February 12, 2004 SourceSNM Reston, VA - Killing the disease without killing the http://interactive.snm.org/index.cfm?PageID=2220&RPID=1316

82. NEJM -- Itraconazole To Prevent Fungal Infections In Chronic Granulomatous Disea Original Article from The New England Journal of Medicine Itraconazoleto Prevent fungal infections in Chronic Granulomatous Disease. http://content.nejm.org/cgi/content/short/348/24/2416

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 348:2416-2422 June 12, 2003 Number 24 Next Itraconazole to Prevent Fungal Infections in Chronic Granulomatous Disease John I. Gallin, M.D., David W. Alling, M.D., Harry L. Malech, M.D., Robert Wesley, Ph.D., Deloris Koziol, Ph.D., Beatriz Marciano, M.D., Eli M. Eisenstein, M.D., Maria L. Turner, M.D., Ellen S. DeCarlo, R.N., Judith M. Starling, R.Ph., and Steven M. Holland, M.D. Full Text PDF PDA Full Text Editorial ... Chapters at Harrison's ABSTRACT Background Chronic granulomatous disease is a rare disorder in which the phagocytes fail to produce hydrogen peroxide. The patients are predisposed to bacterial and fungal infections. Prophylactic antibiotics and interferon gamma have reduced bacterial infections, but there is also the danger of life-threatening fungal infections. We assessed the efficacy of itraconazole as prophylaxis against serious fungal infections in chronic granulomatous disease. Methods Thirty-nine patients at least 5 years old (6 female and 33 male; mean age, 14.9 years) were enrolled in a randomized

83. Fungal Infection: New & Used Books: Find The Lowest Price fungal infections Immune Responses By Juneann W. Murphy, M. Bendinelli, H. FriedmanHardcover / January 1993 / 030644075X Books Similar to fungal infections http://www.fetchbook.info/Fungal_Infection.html

About Bookmark Recommend Us Enhance Your Site ... Help Keyword Title Author ISBN Searched in books for Fungal Infection More than titles matched your search. Search took seconds. By M. D. Richardson D. W. Warnock Paperback / September 2003 / 1405115785 Books Similar to Compare Prices Book Reviews Infection Protection: How to Fight the Germs That Make You Sick By Ronald Klatz Medical Development Management Inc. Staff Paperback / April 2003 / 0060515090 Books Similar to Infection Protection: How to Fight ... Compare Prices Book Reviews Fungal Infection in the Intensive Care Unit By Rosemary A. Barnes David W. Warnock Hardcover / May 2002 / 1402070497 Books Similar to Fungal Infection in the Intensive C...

84. Time Matters When Treating Fungal Infections In Newborns A new UCLA study shows that ‘time matters’ when treating fungal infections inneonates and that earlier treatment can mean the difference between life and http://www.news-medical.net/view_article.asp?id=1107

85. Clinical Trial: Itraconazole For The Prevention Of Fungal Infections In Chronic Itraconazole for the Prevention of fungal infections in Chronic GranulomatousDisease. This study is completed. No fungal infection within the past year. http://www.clinicaltrials.gov/show/NCT00001280

Home Search Browse Resources ... About Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous Disease This study is completed. Sponsored by National Institute of Allergy and Infectious Diseases (NIAID) Purpose Phase Phase II MedlinePlus consumer health information Study Type: Interventional Study Design: Treatment, Safety/Efficacy Further Study Details: Eligibility Genders Eligible for Study: Both Criteria Documented chronic granulomatous disease more than 5 years of age. No fungal infection within the past year. Not currently on other antifungals or have taken other antifungals during the past 3 months. Not currently on phenytoin or rifampin. Negative pregnancy test within 2 weeks of starting protocol. Expected Total Enrollment: 100 Location Information Maryland National Institute of Allergy and Infectious Diseases (NIAID), 9000 Rockville Pike, Bethesda, Maryland, 20892, United States More Information Publications Hardin TC, Graybill JR, Fetchick R, Woestenborghs R, Rinaldi MG, Kuhn JG. Pharmacokinetics of itraconazole following oral administration to normal volunteers. Antimicrob Agents Chemother. 1988 Sep;32(9):1310-3.

86. Untitled Document fungal infections. Candida commonly causes mucocutaneous manifestationsin HIV, such as thrush, esophagitis, and vaginitis. Mucocutaneous http://www.research.bidmc.harvard.edu/VPTutorials/HIV/Toppo06.htm

Virtual Patient Reference Library Opportunistic Infections page Introduction Pneumocystis Pneumonia Toxoplasmosis Mycobacterium avium ... Bacterial Infections last update October 2002 Fungal infections Candida commonly causes mucocutaneous manifestations in HIV, such as thrush, esophagitis, and vaginitis. Mucocutaneous candidiasis rarely becomes invasive and does not need primary prophylaxis. Prophylaxis with fluconazole does decrease the incidence of invasive fungal disease, particularly cryptococcocis. Invasive disease occurs primarily at CD4 counts below 75 cells/mm Primary prophylaxis is not recommended because the two-year incidence of invasive disease with these fungi (cryptococcosis, histoplasmosis, coccidioidomycosis) is relatively low ( <10%), the medication is expensive, and therapy can select out resistant infection with Candida species and torulopsis yeasts. There is a standard recommendation for secondary prophylaxis, or maintenance therapy, once a patient has had invasive fungal disease.

87. Heart Drug Might Help Fight Chronic Fungal Infections June 5, 2003. MEDIA CONTACT Joanna Downer PHONE 410614-5105 E-MAIL jdowner1@jhmi.edu.Heart Drug Might Help Fight Chronic fungal infections. http://www.hopkinsmedicine.org/press/2003/June/030605A.htm

June 5, 2003 MEDIA CONTACT: Joanna Downer PHONE: E-MAIL: jdowner1@jhmi.edu Heart Drug Might Help Fight Chronic Fungal Infections Johns Hopkins scientists have determined why a drug routinely used to treat heart arrhythmias might become a crucial addition to fighting chronic fungal infections, they report online in the Journal of Biological Chemistry. Last year, scientists elsewhere noted the drug's ability to kill fungi. Now, a Johns Hopkins research team has found that amiodarone kills by disrupting cells' interior and exterior calcium balance. Importantly, this is completely different from the way in which commonly used antifungal agents miconazole and fluconazole stop fungal growth, say the researchers. In their experiments, a combination of amiodarone and either of the "azoles" killed dramatically more fungi than expected. "This antiarrhythmic drug, in low doses, combined with azoles looks very promising in the lab and appears to be worth taking a look at clinically," says Rajini Rao, Ph.D., associate professor of physiology in the Johns Hopkins School of Medicine's Institute for Basic Biomedical Sciences. "The azoles prevent fungi from growing, but but doesn't kill all of them the immune system is supposed to do that. Amiodarone kills them instead of keeping them dormant." While fungal infections in general are easy to get rid of, in patients with depressed immune systems or with conditions like cystic fibrosis that increase susceptibility to chronic or recurring fungal infections, prolonged use of azoles can lead to the fungus becoming resistant to treatment. Finding a way to treat severe and life-threatening fungal infections with an option that boosts the effects of azoles without relying on the strength of the immune system is attractive, says Rao, who studies how calcium is brought into cells.

88. Fungal Infections Menu Opportunistic Infections. fungal infections. Aspergilliosis. Candidiasis.Coccidiodomycosis. Cryptococcal Meningitis. Histoplasmosis. Go http://www.hivpositive.com/f-Oi/OppInfections/4-Fungal/4-FungalSubMenu.html

Fungal Infections Aspergilliosis Candidiasis Coccidiodomycosis Cryptococcal Meningitis ... Go to the HIVpositive.com Main Menu

89. USE OF LUFENURON FOR TREATING FUNGAL INFECTIONS OF DOGS AND CATS USE OF LUFENURON FOR TREATING fungal infections OF DOGS AND CATS A SUMMARYOF 297 CLINICAL CASES (19971999). Y. Ben Ziony and B. Arzi. http://www.isrvma.org/article/57_3_99.htm

USE OF LUFENURON FOR TREATING FUNGAL INFECTIONS OF DOGS AND CATS: A SUMMARY OF 297 CLINICAL CASES (1997-1999) Y. Ben Ziony and B. Arzi Ben Ziony Animal Hospital, Kiryat Tivon, Israel Lufenuron (PROGRAM TM ) is an orally administered flea control drug, which acts by inhibiting chitin, liqueflies the eggshell, and so prevents flea multiplication. Fungal cells are also surrounded by a cell wall composed of complex polysaccharides, primarily chitin. Medical records of 138 dogs and 159 cats with dermatophytosis or superficial dermatomycosis and treated with lufenuron, are reviewed. Sixty untreated dermatophytic animals are included as controls. Fungal cultures and direct microscopic identification were performed. The cats were given 51.2 to 266 mg lufenuron/Kg. B.W. The dogs received 54.2 to 68.3 mg. Lufenuron/Kg.B.W. Recovery in cats was extremely rapid: hair started to grow after 5 or 6 days of treatment. The mean clinical recovery time was 11.6 days, while the mean mycological cure time was 8.3 days. In dogs, mean clinical recovery time was 21 days, and mycological cure time in 14.5 days. Negative fungal cultures always preceeded clinical recovery. No side effects or toxicity were encountered. Blood profiles remained unchanged. Untreated control animals recovered spontaneously in 90 days. Treatment aims are to reduce transmission to others and eradicate infection.

90. HBO Therapy Improves Prefabricated Flap Survival The term mucormycosis refers to fungal infections caused by the order Mucorales(of the class phycomycetes.) Within the mucorales order are 4 fungi that are http://www.baromedical.com/newsletter/bartlettarticle.html

Mucormycosis and Hyperbaric Oxygen Therapy The term "mucormycosis" refers to fungal infections caused by the order Mucorales (of the class phycomycetes.) Within the mucorales order are 4 fungi that are clinically important and cannot be distinguished by histopathologic exam alone. They are Absida, Mucor, Rhizomucor, and Rhizopus. These fungi are saprophytic which means they derive energy by breaking down dead organic matter. The phycomycetes are distributed worldwide. This ubiquitous fungus is commonly found in bread and fruit molds, soil, manure, and insects. The potential for infection occurs when spores become airborne and are drawn into the sinuses, ingested with foods or inoculated into traumatized tissue as a soil contaminate. When infection occurs it is opportunistic in nature. This disease is rarely found in patients with no predisposing condition. The presence of systemic or local acidosis is an important risk factor for infection, no matter what causes the acidosis. Several different locations for infection have been described. The rhinocerebral type, which involves various combinations of the sinuses, orbit, and brain, is the most common. Less commonly there may be involvement of the gastrointestinal tract, pulmonary system, or burned or traumatized skin. Pulmonary, gastrointestinal or dermal infections frequently metastasize via the blood stream and spread to the central nervous system. Airborne fungal spores commonly land in the oral and nasal mucosa where they are normally contained by a phagocytic response. In host compromised patients, however, this initial containment may fail, in which case germination ensues and hyphae develop. Hyphae have a prediction for blood vessels. The subintima of local arterioles and arteries are invaded causing mechanical and toxic damage to the intima, which allows for gross invasion of the vessel lumen with subsequent thrombosis, hypoxia, acidosis and hematogenous spread. Hypoxia inhibition of phagocytosis and the local acidosis further enhance fungal growth. The infection typically spreads to the paranasal sinuses and can enter the orbit via the ethmoid and maxillary sinuses. Spread to the brain may occur via the orbital apex, orbital vessels, or via the cribiform plate.

91. FUNGAL INFECTIONS fungal infections. fungal infections of the Skin National Skin Centre http//biomed.nus.sg/nsc/fungal.html. fungal infections Unsightly http://www.ruralfamilymedicine.org/clinical topics/fungal.htm

FUNGAL INFECTIONS Fungal Infections of the Skin: National Skin Centre - http://biomed.nus.sg/nsc/fungal.html Fungal Infections: Unsightly Nails Can Be Embarrassing - http://www.health-line.com/articles/sc950206.html Blastomycosis Coccidioidomycosis Return to: clinical topics home page Comments to: rfd@adams.net

92. Gilead -- Fungal Infections Once rare, systemic fungal infections are becoming increasingly commonin hospital settings. Patients most at risk include transplant http://www.gilead.com/wt/ltd_slideshow/fungal

Once rare, systemic fungal infections are becoming increasingly common in hospital settings. Patients most at risk include transplant and chemotherapy patients, HIV patients, elderly patients and patients with compromised immune systems. Some of the most common blood-borne fungal infections are aspergillosis, candidiasis and cryptococcosis. Fortunately, many systemic fungal infections can be effectively treated with currently available therapeutics.

93. Fungal Infections fungal infections. Ringworm of cattle. Published on the Web by theVeterinary Science Extension of Purdue University, and written http://vetgate.ac.uk/browse/cabi/451b39dcc9eb6e7542b49f597323a01a.html

low graphics fungal infections Ringworm of cattle Published on the Web by the Veterinary Science Extension of Purdue University, and written by RL Morter DVM, and C James Callahan DVM, this fact sheet presents information on the fungal infection ringworm in cattle, due to the fungus Trichophyton verrucosum . It looks at the causes, transmission, treatments, and preventitive measures. fungal infections disease prevention cattle diseases Trichophyton verrucosum ... cats Last modified: 27 May 2004

94. Janssen Pharmaceutica fungal infections. We distinguish between fungal infections of the body surfacesand systemic fungal infections (which affect the whole body or an organ). http://www.janssenpharmaceutica.be/health_diseases_1_E.asp

Nederlands Diseases Fungal infections Occasionally, however, this peaceful coexistence goes wrong and a harmless fungal inhabitant becomes troublesome. We distinguish between fungal infections of the body surfaces and systemic fungal infections (which affect the whole body or an organ). Fungal infections of body surfaces Onychomycosis, for instance, affects 1 to 3% of the population, and is characterised by discoloration and thickening of the nail and detachment of the nail plate from the nail bed. Toenails, which are frequently the primary site of infection, are often thick, yellow and brittle, and debris accumulates under the nail. Systemic fungal infections Although systemic fungal infections are relatively rare, their incidence has risen during the past 20 years. This is because of increases in the number of people with diminished or impaired immunity. Immune defences are reduced during certain hospital treatments, such as chemotherapy for cancer, and in some diseases, such as HIV infection.

95. Fungal Infections Lawsuit Overview - Find Trial Lawyers And Attorneys With Exper fungal infections Overview fungal infections Overview - Find Trial Lawyersand Attorneys with Experience in fungal infections Personal Injury Law. http://www.injuryboard.com/view.cfm/Topic=268

June 2, 2004 Bayer Corporation has faced thousands of lawsuits over its withdrawn cholesterol medication Baycol Vioxx / Rofecoxib Tractor-Trailer Accidents Serzone / Nefazodone Hydrochloride ... Skin Disorders Fungal Infections: Overview If you or a family member has been injured, contact a personal injury attorney today. Just fill out InjuryBoard.com's on-line questionnaire and have a personal injury lawyer review your potential personal injury claim - free of charge. Ask an Attorney Fungi cause fungal infections. These fungi surround us and frequently land on our skin and are inhaled into our lungs . Many fungi are harmless, some cause minor and irritating infections , while a few can cause much more severe infections. People with compromised immune systems , such as AIDS and cancer patients, may be more susceptible to fungal infections than others. Would you like to use this material on your law firm web site? What do I do Now? As with many personal injury claims, time is critical.

96. Fungal Infections Detailed information on fungal skin infections, including Candidiasis,Tinea Infections, and Tinea Versicolor. fungal infections. http://www.healthsystem.virginia.edu/uvahealth/peds_derm/fsihub.cfm

@import url(/assets/UVAHealth/ssi/css/greystone_advance.css); Adolescent Medicine Allergy/Asthma/Immunology Blood Disorders Burns Cancer Common Injuries/Poison Tips Craniofacial Anomalies Dermatology Diabetes/Endo/Metabolism Eye Care Genitourinary/Kidney High-Risk Newborn High-Risk Pregnancy Infectious Diseases Medical Genetics Mental Health Nervous System Disorders Normal Newborns Oral Health Orthopaedics Pediatric Surgery Respiratory Disorders Terminal Illness in Children Transplantation FIND A DOCTOR MAKE AN APPOINTMENT CALENDAR OF EVENTS CLINICAL TRIALS Fungal Infections Skin fungi live in the dead, top layer of skin cells in moist areas of the body, such as between the toes, groin, and diaper area. Some fungal infections cause only a small amount of irritation. Other types of fungal infections penetrate deeper and may cause itching, swelling, blistering, and scaling. In some cases, fungal infections can cause reactions elsewhere on the body. For example, a child may develop a rash on the finger or hand associated with an infection of the scalp or foot. There are many different types of fungal skin infections that require clinical care by a physician or other healthcare professional. Listed in the directory below are some, for which we have provided a brief overview.

97. Fungal Infections Of The Skin Detailed information on fungal infections of the skin, including candidiasis(yeast infection), tinea infection (ringworm), and tinea versicolor. http://www.healthsystem.virginia.edu/uvahealth/adult_derm/fungal.cfm

@import url(/assets/UVAHealth/ssi/css/greystone_advance.css); Blood Disorders Bone Disorders Breast Health Cardiovascular Disease Dermatology Diabetes Digestive Disorders Endocrinology Environmental Medicine Eye Care Glossary Gynecological Health Infectious Diseases Kidney Disease Men's Health Mental Health Nervous System Disorders Non-Trauma Emergency Oral Health Orthopaedics Otolaryngology Pathology Pediatrics, General Health Prostate Health Radiology Respiratory Disorders Skin Cancer Surgical Care Urology Women's Health FIND A DOCTOR MAKE AN APPOINTMENT CALENDAR OF EVENTS CLINICAL TRIALS Fungal Infections of the Skin Skin fungi live in the dead, top layer of skin cells in moist areas of the body, such as between the toes, groin, and under the breasts. These fungal infections cause only a small amount of irritation. Other types of fungal infections penetrate deeper and may cause itching, swelling, blistering, and scaling. In some cases, fungal infections can cause reactions elsewhere on the body. For example, a person may develop a rash on the finger or hand after touching an infected foot. There are many types of fungal skin infections that require clinical care by a physician or other healthcare professional. Listed in the directory below are some, for which we have provided a brief overview.

98. Pharmalicensing.com: Articles: A Tour Around Fungal Infections Profile Now! A Tour around fungal infections. InPharm Tours (8 November2001). By Geoff Barnett. Freelance Medical Writer and Editor. http://www.pharmalicensing.com/features/disp/1005230974_3bea9b7e6644e

Navigation Resources Events Industry news Articles ... Corporate A Tour around Fungal Infections (8 November 2001) By Geoff Barnett Freelance Medical Writer and Editor Not so long ago it was all very simple: living things belonged to one of two kingdoms - plant and animal; at least that's what I was taught. But as our biological knowledge expanded, it became increasingly difficult to rationally place some living things into either kingdom. Now most biologists recognise five kingdoms; plants, animals, fungi and two others. Discover their names and read summaries of the main characteristics of all five at Five Kingdom Classification System Fungi, which include yeasts, moulds, smuts and mushrooms, are responsible for causing four types of mycotic disease: 1. Hypersensitivity - an allergic reaction to moulds and spores; 2. Mycotoxicosis - poisoning by food products contaminated by fungi; 3. Mycetismus - the ingestion of preformed toxin (toadstool poisoning) 4. Infection - the subject of this Tour. Depending on how they are classified there are between 100,000 and 200,000 species of fungi. Only a few hundred are pathogenic to man and

99. The Leading Fungal Infections Site On The Net TOP WEB RESULTS FOR fungal infections. 1. Fast Relief from FungalInfections Fast relief, allnatural, no drug side effects. Kills http://www.deafcanada.com/search.php?term=Fungal Infections&fmt=bot

100. EMedicine - Hospital-Acquired Infections : Article By Quoc V Nguyen, MD Physician reports on the viral, bacterial, and fungal pathogens likely to cause nosocomial infections such as pneumonia, urinary tract infection, colitis, and candidiasis. Includes medical care and prevention tips. http://www.emedicine.com/ped/topic1619.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Infectious Diseases Hospital-Acquired Infections Last Updated: October 22, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: nosocomial infection, vancomycin-resistant enterococcus, VRE, methicillin-resistant Staphylococcus aureus, MRSA, Pseudomonas, candidiasis, Legionella, respiratory syncytial virus, thrush, Clostridium difficile AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Quoc V Nguyen, MD , Assistant Professor, Department of Pediatrics, State University of New York at Syracuse Quoc V Nguyen, MD, is a member of the following medical societies: American Association of Immunologists Editor(s): David Jaimovich, MD , Section Chief, Division of Critical Care, Hope Children's Hospital, Assistant Professor Pediatrics, Assistant Professor, Department of Pediatrics, University of Illinois at Chicago; Robert Konop, PharmD

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