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         Fanconi Anemia:     more books (28)
  1. Fanconi anemia: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Mary, MS Freivogel, 2005
  2. Gale Encyclopedia of Cancer: Fanconi anemia by M.S., J.D. Michelle Johnson, 2002-01-01
  3. Fanconi Anemia : Guidelines for Diagnosis and Management by Fanconi Anemia Research Fund, 2008
  4. The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC [An article from: DNA Repair] by F. Leveille, M. Ferrer, et all 2006-05-10
  5. Chromosome Instability Syndromes: Ataxia Telangiectasia, Fanconi Anemia, Bloom Syndrome, Nijmegen Breakage Syndrome
  6. Molecular Mechanisms of Fanconi Anemia by Shamim I. Ahmad, 1980
  7. C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair [An article from: DNA Repair] by S.J. Collis, L.J. Barber, et all 2006-11-08
  8. Interstrand crosslink-induced radials form between non-homologous chromosomes, but are absent in sex chromosomes [An article from: DNA Repair] by A.E. Newell, Y.M.N. Akkari, et all 2004-05-04
  9. Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells [An article from: DNA Repair] by J.M. Hinz, N.A. Yamada, et all
  10. Drosophila homologs of FANCD2 and FANCL function in DNA repair [An article from: DNA Repair] by L.R. Marek, A.E. Bale, 2006-11-08
  11. Role of the Fancg gene in protecting cells from particulate chromate-induced chromosome instability [An article from: Mut.Res.-Genetic Toxicology and Environmental Mutagenesis] by L.C. Savery, E. Grlickova-Duzevik, et all 2007-01-10
  12. FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: Activation is not required for repair of Cr(VI)-induced DSBs [An article ... Toxicology and Environmental Mutagenesis] by S.K. Vilcheck, S. Ceryak, et all 2006-11-07
  13. Two in a Million: A True Story about Illness and Love by Ben Murnane, 2008-01
  14. Saving Henry: A Mother's Journey by Laurie Strongin, 2010-03-02

21. Fanconi Anemia Fact Sheet - University Of Pittsburgh
Brochure about its diagnosis and treatment published by the University of Pittsburgh Department of Human Genetics, including links to support and diagnosis resources.
http://www.pitt.edu/~edugene/Fanconi.pdf

22. Entrez PubMed
Click here to read fanconi anemia complementation group C is required for proliferation of murine primordial germ cells. Nadler JJ, Braun RE.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?holding=npg&cmd=Retrieve&db=PubMed

23. EMedicine - Anemia, Fanconi : Article By Blanche Alter, MD, MPH
Anemia, Fanconi fanconi anemia (FA) is the most frequently reported of the rare inherited bone marrow failure syndromes, with more than 1200 cases reported
http://www.emedicine.com/ped/topic3022.htm
(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Hematology
Anemia, Fanconi
Last Updated: February 26, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: Fanconi anemia, FA, constitutional aplastic anemia, bone marrow failure, aplastic anemia, leukemia, myelodysplastic syndrome, liver adenoma, hepatoma, radial ray anomalies, poor growth, genitourinary problems, short stature, skin pigmentation, café au lait spots, petechiae, bruises, bruising, pallor, fatigue, infections, thumb anomalies, thumb and radial anomalies, abnormal male gonads, microcephaly, eye anomalies, structural renal defects, low birth weight, developmental delay, abnormal ears abnormal hearing, Estren Dameshek Fanconi anemia AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography
Author: Blanche Alter, MD, MPH , Expert, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, Warren Magnuson Clinical Center, National Institutes of Health

24. VU University Medical Center, European Fanconi Anemia Center Amsterdam

http://www.vumc.nl/fa/

25. WELCOME TO FANCONI CANADA
Canadian charity whose mission is to fund medical research into finding a cure for fanconi anemia and to serve as a support network for affected Canadian families.
http://www.fanconicanada.org
FANCONI CANADA
Home

Fanconi Anemia

About Fanconi Canada

FA News
...
Donate Now

FAMILIES
Family Welcome Page

PHYSICIANS/RESEARCHERS
Sitemap
Home Virtual Office of
GIVE THEM TOMORROW
Welcome to the home of Fanconi Canada on the world wide web. Pour francais, pousser ici
OUR MISSION
Fanconi Canada is a registered charity whose mission is to fund research in Canada into an effective treatment and, ultimately, a cure for Fanconi Anemia and to serve as a support network for affected Canadian families.
Canada Customs and Revenue Agency registration no. 868951724 RR 0001 (formerly 890840549 RR 0001)
Thanks for Visiting! Canadian Fanconi Anemia Research Fund / La Fondation Canadienne de Recherche de L'Anemie de Fanconi Home Fanconi Anemia About Fanconi Canada FA News ... Family Welcome Page

26. Fanconi Anemia - Information / Diagnosis / Treatment / Prevention
fanconi anemia. Information • Diagnosis • Treatment • Prevention. Adam Day Learn about a boy who passed away after a fight with fanconi anemia.
http://www.healthcyclopedia.com/blood-disorders/anemia/fanconi.html

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Related Topics: Genetic Disorders Rare Disorders Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "Fanconi's anaemia" Health News: Search millions of published articles for news on Fanconi Anemia Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Adam Day Learn about a boy who passed away after a fight with Fanconi anemia. Find out how to make a donation to the Fanconi Anemia Research Fund. Alex and Matt Pearl Personal stories of two children fighting Fanconi Anemia. B Positive, Inc.

27. B+ Home
A charitable organization providing assistance to children with fanconi anemia within the St. Louis and St. Charles Missouri metro areas.
http://www.bpositiveinc.com
B Positive! Bone Marrow Drive
Schedule
UPDATE B Positive, Inc.
P.O. Box 533
Chesterfield, Mo. 63006-0533
(314) 503-BPOS (2767)
In December, 2000, two
St. Louis area siblings,
Matthew Pearl, age 4, and
Alexandra Pearl, age 6,
were diagnosed with
Fanconi Anemia
. At the
same time, they discovered that each child had B+ blood types and that their only hope for finding a cure was successful bone marrow transplant. The odds of any given individual, other than an immediate family member, being a perfect match is about one in a million. Alex received her bone marrow transplant in May, 2001 and is recovering well... however, no match for Matt has been found yet. We need your help! For more about Alex and Matt, visit their web site at www.alexandmatt.com Welcome to the B Positive, Inc. Web Site! 2nd Annual Fund Raising Event; SAVE A LIFE ~ WIN THIS HARLEY! Here’s your chance to help Children in Need, and win this Brand New 100th Anniversary 2003 Harley-Davidson. Valued approximately at $20,000. Tickets are $10 each and are available at www.alexandmatt.com

28. GeneReviews: Fanconi Anemia
Your browser does not support HTML frames so you must view fanconi anemia in a slightly less readable form. Please follow this link to do so.
http://www.geneclinics.org/profiles/fa&id=8888888&key=vLsPZfF5ieW3O
Your browser does not support HTML frames so you must view Fanconi Anemia in a slightly less readable form. Please follow this link to do so.

29. Alex And Matt Pearl
Personal stories of two children fighting fanconi anemia.
http://www.alexandmatt.com
(or download a Alex Pearl with
Ram's Cheerleaders
(click photo to enlarge) more photos here Hi, most of you may know our story; we are Alexandra and Matthew Pearl. In December 2000 and January 2001 we were both diagnosed with a rare, life threatening blood disease called Fanconi anemia. It causes bone marrow failure; our bodies cannot make the blood we need to survive. Our only hope is a bone marrow transplant. Alex has found a perfect match and is recovering from her May 31, 2001 transplant in Cincinnati, Ohio. There is no perfect match for Matthew, in any registry throughout the entire world. We need your help, please consider getting added to the National Bone Marrow Registry through the Pearl Million-Donor March. Refer to the ' How You Can Help ' section.
Pearl Family Million

Donor March

Presentation (PPT)
My little girl (PPT) ... more docs, click here Who knows, maybe you could be the perfect match that saves Matthew's or the 3,000 others in need. Thanks to all who have helped to add more than 80,000 people to the registry, that have resulted in at least 100 matches for others. It is a good start, but there is much work to be done. God Bless and Thank you

30. BioMed Central | Full Text | Fanconi Anemia Genes Are Highly Expressed In Primit
fanconi anemia genes are highly expressed in primitive CD34 + hematopoietic cells Michel Aubé 1 , 2 , Matthieu Lafrance 1 , 2 , Isabelle Brodeur 1 , 2 , Marie
http://www.biomedcentral.com/1471-2326/3/1
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PubMed record ... Related articles in PubMed Search PubMed For Lafrance M Brodeur I Delisle MC Carreau M Key E-mail Corresponding author Research article Fanconi anemia genes are highly expressed in primitive CD34 hematopoietic cells Matthieu Lafrance Isabelle Brodeur Marie-Chantal Delisle and Madeleine Carreau BMC Blood Disorders The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2326/3/1 Received Accepted Published Outline Abstract Abstract Background Methods Results ... Pre-publication history Background Fanconi anemia (FA) is a complex recessive genetic disease characterized by progressive bone marrow failure (BM) and a predisposition to cancer. We have previously shown using the Fancc mouse model that the progressive BM failure results from a hematopoietic stem cell defect suggesting that function of the FA genes may reside in primitive hematopoietic stem cells. Methods Since genes involved in stem cell differentiation and/or maintenance are usually regulated at the transcription level, we used a semiquantitative RT-PCR method to evaluate FA gene transcript levels in purified hematopoietic stem cells.

31. Adam Day
Learn about a boy who passed away after a fight with fanconi anemia. Find out how to make a donation to the fanconi anemia Research Fund.
http://www.adam.interactiveinc.com/
Posted by Darla on February 28, 1997 at 03:02:11:
Soaring with angels Greetings All:
We, again would like to thank everyone for their sincere and heartfelt support. We literally could not have come as far as we did without all of you. We regretfully inform you all that Adam passed away at 9:11 PM, Minnesota time, on February 27, 1997. He was peaceful and pain-free when he passed. His family was with him, as was most of the staff from 4A, who have care for him in the entire duration of our stay here. We will happily inform everyone, though that Adam is now soaring with the angels, watching down protectively on all of us. We're sure he is having go-cart races with Mark Muellen and showing his knife collection to Joey Adamson and fishing with John Dumouchel. We will miss him but we know he is in a better place. May God bless all of you and shower you with goodness, health and many miracles. Thank you again. The Day Family Adam's Uncle Bob went to Minnesota during 1/30-2/3 and took some photos. Adam was in great spirits despite the constant interruptions by a wide variety of physicians and assistants. Go to: http://www.geocities.com/Heartland/Hills/2219/

32. The Scientist :: BRCA2 Loss In Fanconi Anemia
BRCA2 loss in fanconi anemia. Analysis of fanconi anemia cell lines reveals deletions in the breast cancer susceptibility gene BRCA2. By Jonathan B Weitzman.
http://www.biomedcentral.com/news/20020614/01/
Previous Next
BRCA2 loss in Fanconi Anemia
Analysis of Fanconi Anemia cell lines reveals deletions in the breast cancer susceptibility gene By Jonathan B Weitzman
Fanconi Anemia (FA) is a recessive cancer susceptibility syndrome. Six FA genes have been cloned and encode proteins involved in a DNA-damage response pathway. In the June 13 ScienceXpress , Niall Howlett and colleagues report the characterization of mutations in cells from the FA subtypes B and D1 ( ScienceXpress 2002, DOI:10.1126/science.1073834). They discovered biallelic mutations in the breast cancer susceptibility gene; the mutations create frameshifts resulting in truncated BRCA2 protein. Howlett et al. show that restoring expression could rescue the phenotype of FA cells and restore resistance to DNA-damaging agents. The authors propose a model linking FA-associated genes to the regulation of a common DNA-damage response pathway. Links for this article
Fanconi anemia and DNA repair
PubMed Abstract

Interaction of the Fanconi anemia proteins and in a common pathway.

33. Comprehensive Center For Fanconi Anemia
A fanconi anemia and Chromosome Instability Center has been established at DanaFarber Cancer Institute and Children s Hospital in Boston.
http://research.dfci.harvard.edu/dandrealab/fanconianemia.html
Comprehensive Center For Fanconi Anemia Dana Farber Cancer Institute
A Fanconi Anemia and Chromosome Instability Center has been established at Dana-Farber Cancer Institute and Children's Hospital in Boston. The center is directed by Dr. Alan D'Andrea, M.D., Professor of Pediatrics. This Center offers a wide range of services including: o A basic research program in the molecular and cellular biology of Fanconi Anemia, conducted in the laboratory of Dr. D'Andrea. o The creation of a Fanconi Anemia patient cell repository, including lymphoblastoid cell lines, skin fibroblast cell lines, and tumor cell lines from patients and family members. This repository has been assembled in collaboration with Dr. Markus Grompe and the Oregon Health Sciences University (OHSU). o A Registry of FA patients from across the United States and Canada, including clinical information and family history. o A Cytogenetics Core Laboratory at the Dana-Farber (Mayer Bldg., room 676) (headed by Lisa Moreau ) for diagnosis, DEB testing, complementation group analysis, and carrier detection. o A diagnostic and evaluation center for new and known patients with Fanconi Anemia, which is directed by

34. Fanconi Anemia Research Studies
edu). Consent Form Back to Top. Development of New Clinical Tests for the Diagnosis and Management of fanconi anemia Back to Top.
http://research.dfci.harvard.edu/dandrealab/faresearch.html
Fanconi Anemia Research Studies Subtyping Mutational Analysis Amifostine Tumor Studies ... Development of New Clinical Tests for the Diagnosis and Management of Fanconi Anemia Subtyping:
  • Description:
  • Our laboratory is performing subtyping analysis on a research basis. A small sample of blood (about one teaspoon) obtained at a time when blood is being drawn for clinical reasons can be used for these studies. The blood cells (lymphocytes) are immortalized with a virus (Epstein Barr virus or EBV, which is the virus that causes mononucleosis) and grown in culture for testing. The patient's subtype is identified by testing the ability of an introduced Fanconi gene (A, C, D2, E, F, or G) to correct the cell's sensitivity to DNA damaging agents such as mitomycin C (MMC) or diepoxybutane (DEB). Fanconi cells cannot repair the DNA damage inflicted by these agents. Introduction of the functional homologue of the defective Fanconi gene can restore the cellsâ ability to repair its DNA. The cells are then frozen and stored for additional studies. A family can choose to withdraw from these studies at any time. These tests take several weeks to complete. Sometimes, cells from Fanconi patients do not grow well in culture. We would let you know if this were the case, and you would have the option of submitting another sample for testing.

35. Fanconi Anemia Comprehensive Care Center, Cincinnati Children's Hospital Medical
The fanconi anemia Comprehensive Care Center at Cincinnati Children s Hospital Medical Center cares for kids with fanconi anemia and rare bone marrow failure
http://www.cincinnatichildrens.org/svc/prog/blood/programs/fanconi-anemia/
Home Contact Us Site Map Go to Advanced Search ... Fanconi Anemia Comprehensive Care Center Overview Related Resources Faculty Hemophilia Program Sickle Cell Center ... How to Help
Fanconi Anemia Comprehensive Care Center
Overview
The Fanconi Anemia Comprehensive Care Center at Cincinnati Children's Hospital Medical Center is a first-of-its-kind center in the United States dedicated to compassionate, multidisciplinary care of children with Fanconi anemia (FA) and other rare bone marrow failure syndromes. Distinguished experts Richard Harris, MD David Williams, MD and Frank Smith, MD lead a team of specialists to deliver organized, outstanding medical, surgical and behavioral care at multiple levels. The Fanconi Anemia Comprehensive Care Center devotes itself to a unique focus on care for children with Fanconi anemia and support for their families.
Multidisciplinary Approach
The Fanconi Anemia Comprehensive Care Center provides a multidisciplinary approach to caring for children with Fanconi anemia and other rare bone marrow failure syndromes. Collectively, experts from numerous areas of specialty offer children and their families optimal care. The Fanconi Anemia Comprehensive Care Center designs personalized, ongoing treatment regimens for patients, delivered by specialists in the following areas:

36. Fairview-University Blood And Marrow Transplant Services
fanconi anemia Comprehensive Care Program. The fanconi anemia Comprehensive Care Program at FairviewUniversity Medical Center is
http://www.fairviewbmt.org/fanconi.asp
Behavioral/Chemical
Dependency

Blood/Marrow Transplant

Brain Tumor Center
...
and the Family

University of Minnesota
Academic Health Center

UMPhysicians

'Ask the Doctor' Radio

Press Room
...
Fairview Rehabilitation Services
Hospitals: Children's Fairview- University Medical Center Lakes Northland ... Twin Cities Information Articles: BMT Newsletter : Cord blood transplants for adults; Advances in cell transplantation for FA Umbilical Cord Blood Transplantation Fanconi Anemia Grant from Wasie Foundation Assists Renovation of Pediatric BMT Unit Fanconi Anemia Comprehensive Care Program The Fanconi Anemia Comprehensive Care Program at Fairview-University Medical Center is the single largest treatment center for patients with Fanconi Anemia (FA) in the United States.  The care provided is individually tailored to meet the unique needs of each patient and family. This program uses a team of expert health care providers who specialize in FA, applying leading-edge research developed by University of Minnesota scientists.  Our Expertise Fairview-University Blood and Marrow Transplant (BMT) Services, affiliated with the University of Minnesota has set the standard for BMT as a treatment for Fanconi Anemia and other diseases since University of Minnesota physicians performed the world's first successful BMT in 1968. University of Minnesota physicians have performed sibling donor transplants for FA since 1976 and unrelated donor transplants for FA since 1987.

37. Fanconi Anemia
fanconi anemia Fanconi s Anemia. Page, Marrow Index.
http://www.fpnotebook.com/HEM134.htm
Home About Links Index ... Editor's Choice document.write(code); Advertisement Hematology and Oncology Marrow Anemia ... Aplastic Anemia Fanconi Anemia Assorted Pages Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia Rubra Vera ... Bone Marrow Aspiration Fanconi Anemia Fanconi's Anemia Congenital Pancytopenia Diamond-Blackfan Anemia Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Sarcoma Surgery Symptom Evaluation Vascular Page Marrow Index Anemia Aplastic Anemia Fanconi Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia
  • Epidemiology Incidence : 1 in 60,000 to 300,000 births
  • 38. FANCC - Fanconi Anemia, Complementation Group C - Aka: FAC, FACC - Cancer Geneti
    FANCC; fanconi anemia, complementation group C. Human alpha Spectrin II and the fanconi anemia Proteins FANCA and FANCC Interact to Form a Nuclear Complex.
    http://www.cancerindex.org/geneweb/FANCC.htm
    Cancer Genetics Web
    www.cancer genetics.org
    FANCC ; Fanconi anemia, complementation group C (9q22.3) FANCC Menu Summary Information - FANCC
    Gene Database Entries for FANCC

    Other FANCC Related Resources

    FANCC - Fanconi Anaemia Complementation Group C
    ...
    Feedback / suggest a new topic for FANCC

    Search: Summary Information
    FANCC; Fanconi anemia, complementation group C
    Location: Aliases: FAC, FACC Return to FANCC Contents
    Gene Database Entries for FANCC
    OMIM

    GeneCard
    (Weizmann Institute)
    Atlas of Genetics and Cytogenetics in Oncology and Haematology
    Human Gene Mutation Database (Cardiff, UK) Genbank Locus Link UniGene GenAtlas ... Nomenclature (search for FANCC) Return to FANCC Contents Other Related Resources Fanconi Anaemia Resources
  • Medline Search: (FACC OR FAC OR FANCC) AND FANCONI ANAEMIA (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews]
  • Medline Search: FACC OR FAC OR FANCC (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews]
    Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (FANCC[TI] OR FAC[TI] OR FACC[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews]
  • Return to FANCC Contents FANCC - Fanconi Anaemia Complementation Group C
  • McMahon LW, et al.
  • 39. Fanconi Anemia - Medical Dictionary Definitions Of Popular Medical Terms
    MedicineNet Home MedTerms medical dictionary AZ List fanconi anemia. Advanced Search. Inheritance fanconi anemia is an autosomal recessive condition.
    http://www.medterms.com/script/main/art.asp?articlekey=9616

    40. Center For Jewish Genetic Diseases - Department Of Human Genetics - Mount Sinai
    Diseases fanconi anemia. Short stature is commonly observed in children and adults with fanconi anemia, and other growth measurements may also be below normal.
    http://www.mssm.edu/jewish_genetics/diseases/fanconi_anemia.shtml
    Diseases: Fanconi Anemia anconi anemia is a blood disorder characterized by pancytopenia (deficiency of red blood cells, white blood cells and platelets), increased risk for cancer, and congenital birth defects. The disease is highly variable and is frequently associated with cardiac, kidney and limb abnormalities. Short stature is commonly observed in children and adults with Fanconi anemia, and other growth measurements may also be below normal. Bleeding episodes and bruising are common, as are hormonal problems and infertility. The majority of individuals with Fanconi anemia are diagnosed during childhood, but many do not survive beyond young adulthood. This is frequently a result of leukemia or other cancers, which are due to bone marrow failure. Treatment for Fanconi anemia is primarily preventive. Individuals with Fanconi anemia may pursue bone marrow transplantation on an experimental basis, however there is to date no consistently effective treatment. In order to detect cancers early, individuals with Fanconi anemia should arrange for frequent screenings. In addition, avoidance of sun exposure and other agents which may damage the chromosomes is imperative. Although five subtypes of Fanconi Anemia exist, it is only Type C that occurs with increased frequency among individuals with Ashkenazi Jewish ancestry. It is estimated that approximately 1 in 89 Ashkenazi Jewish individuals are carriers of Type C. All types of Fanconi anemia are inherited in an

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