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         Extrapontine Myelinolysis:     more detail
  1. Methylphenidate Treatment of Neuropsychiatric Symptoms of Central and Extrapontine Myelinolysis(*).: An article from: Journal of Studies on Alcohol by Denise Bridgeford, David B. Arciniegas, et all 2000-09-01

21. Penn State Faculty Research Expertise Database (FRED)
Related Terms, Central Pontine Myelinolysis, extrapontine myelinolysis. Myelinolyses,Extrapontine, Myelinolysis, Extrapontine. Faculty Experts,
http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D017590

22. Myelinolysis, Central Pontine
Central Pontine Myelinolysis; extrapontine myelinolysis; Extrapontine Myelinoclasis;Myelinoclasis, Central Pontine; Pontine Myelinolysis, Central; Central
http://medical.webends.com/kw/Myelinolysis, Central Pontine
Medical.WebEnds.com - Medical Terminology Dictionary
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Myelinolysis, Central Pontine
Central Pontine Myelinolysis; Extrapontine Myelinolysis; Extrapontine Myelinoclasis; Myelinoclasis, Central Pontine; Pontine Myelinolysis, Central; Central Pontine Myelinoclasis; Extrapontine Myelinoclases; Extrapontine Myelinolyses A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA DYSARTHRIA ; DYSPHAGIA; and alterations of consciousness . Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons . This condition is usually associated with systemic disorders such as HYPONATREMIA ; chronic ALCOHOLISM LIVER FAILURE ; severe BURNS ; malignant NEOPLASMS ; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS . The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology , 6th ed, pp1125-6)
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23. PharmGKB: Myelinolysis, Central Pontine
Pontine Myelinolysis; Extrapontine Myelinoclases; Extrapontine Myelinoclasis; ExtrapontineMyelinolyses; extrapontine myelinolysis; Myelinoclases, Extrapontine
http://www.pharmgkb.org/do/serve?objId=PA446520&objCls=Disease

24. Neuroradiology Cases
extrapontine myelinolysis. extrapontine myelinolysis 1; extrapontine myelinolysis2; extrapontine myelinolysis 3. Giant Calvarial Epidermoid.
http://www.gastonradiology.com/cases/ix_cases_neurorad.html
Sturge Weber Cryptococcal Meningitis Spinal Schwannoma AV Fistula Cavernous Sinus Dandy Walker Cyst 18doF Air in Cavernous Sinus (S/P IV) Huge Cavum Septum Pellucidum Intraventricular Meningioma Subacute Basal Ganglia Infarct Cavernous Carotid Aneurysm Anterior Cerebral Artery Infarct w/ Hyperdense ACA Alcoholic S/P Multiple Trauma Chronic Frontal Infarct w/ Wallerian Degeneration Hyperostotic Meningioma 16yoM - Ependymal Cyst Epidural Abscess Chiari 1 Subacute Infarcts-Vasculitis Agenesis Of Corpus Callosum Bilateral Subdural Hematomas Bizarre Fused Vertebrae Choroid Plexus Cyst Ependymoma Cauda Equina Epidural Hematoma Equine ACA Extrapontine Myelinolysis

25. La Imagen Del Mes
Translate this page A manifestation of extrapontine myelinolysis confirmed by magnetic resonanceimaging. MR imaging of pontine and extrapontine myelinolysis.
http://www.rochelink.roche.com.ar/pub/rnarg/med/revista1/imagen.htm
Este sitio esta auspiciado por: La imagen del mes J.A. Ure, M.V. Diez, H.O. Videla, J.A. Ollari, S. Zajic Mielinolisis osmótica, pontina y extrapontina La mielinolisis osmótica, descripta por Adams en 1959 , suele manifestarse en forma aguda con alteraciones de la conciencia, incontinencia urinaria, trastornos del equilibrio, tetraparesia y síndrome pseudobulbar, caracterizado por inmovilidad de la lengua, disartria, trastornos deglutorios, y en ocasiones risa y/o llanto espasmódico. La lesión patológica característica de la afección es una desmielinización simétrica de la base pontina con proliferación astrocitaria, centrífuga desde el rafe medio, que compromete a las fibras transversales respetando a las longitudinales ventrolaterales, a las neuronas y a los vasos sanguíneos, con escaso componente edematoso o inflamatorio. En los casos más graves la lesión puede cavitarse y/o extenderse hacia el mesencéfalo. Se han reportado casos con desmielinización extrapontina en sitios tales como el cuerpo estriado, el tálamo, el núcleo geniculado lateral, la substancia blanca del cerebelo o subcortical, etc. La imagen puede verse en la RMN como una hipointensidad en T1 - hiperintensidad en T2, aunque hiperintensidad en T1 también ha sido reportada

26. AJNR -- Sign In Page
serial imaging (1–3). There have been a few reports describing findings of diffusionweightedimaging (DWI) in CPM and extrapontine myelinolysis (EPM) (4, 5
http://intl.ajnr.org/cgi/content/full/25/2/210
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Early Diagnosis of Central Pontine Myelinolysis with Diffusion-Weighted Imaging
Ruzek et al. AJNR Am J Neuroradiol.
Abstract of this Article
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27. Alcohol Research Center - Marchiafava-Bignami Sydrome - Louisiana
Am Fam Phys 1987;3516770. 19. Gabriel S, Grossmann A, Hoppner J, Benecke R,Rolfs A Marchiafava-Bignami syndrome. extrapontine myelinolysis in
http://alcoholresearch.lsuhsc.edu/effects/bignami.asp

28. Blackwell Synergy - Cookie Absent
time in the middle cerebellar peduncle and in the dorsal limbs of the capsula interna,a common location of extrapontine myelinolysis (BekiesinskaFigatowska
http://www.blackwell-synergy.com/links/doi/10.1046/j.1468-1331.2002.04454.x/abs/
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29. Arquivos De Neuro-Psiquiatria - B Central Pontine And Extra
Translate this page Pontine and extrapontine myelinolysis following liver transplantation. Extrapontinemyelinolysis after correction of chronic hyponatremia with isotonic saline.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000600028&l

30. Artículo 34: Movimientos Anormales En Un Caso De Mielinólisis Extrapontina. Re
Translate this page - Abnormal movements in a case of extrapontine myelinolysis. Lateral pontine andextrapontine myelinolysis associated with hypernatremia and hyperglycemia.
http://www.infodoctor.org/neuro/Art34.htm
Principal Mapa Presentación Artículos ... Novedades Movimientos anormales en un caso
de Mielinólisis Extrapontina.
Revisión de la literatura - Abnormal movements in a case of
extrapontine myelinolysis.
Review of the literature -
D. Ezpeleta, C. de Andrés*, S. Giménez-Roldán*.
Servicio de Neurología, Hospital General Universitario Gregorio Marañón, Madrid. Publicado en 1998 en Revista de Neurología
MEDLINE
Resumen. Summary Introduction and clinical case. We present a case of extra-pontine myelinolysis caused by acute hypernatraemia in which a complex picture of late onset extrapyramidal features, choreodystonia and parkinsonism developed. Repeated physical examinations, neurophysiological and neuroimaging studies using magnetic resonance all indicated an extra-pontine site of the lesions, which symmetrically affected the striate and to a lesser extent both thalami. We review the relevant literature available and analyze the cases described as having abnormal movements associated with a myelinolytic syndrome. Conclusions.

31. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/E
Essential Tremor@ (2); extrapontine myelinolysis@ (3); Eye Cancer@(37). News about E More news about E . Books about E 1. Books
http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/E
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32. Demyelinating Diseases - Myelinolysis, Central Pontine
Catatonia due to central pontine and extrapontine myelinolysis case report. Parkinsonismand dystonia in central pontine and extrapontine myelinolysis.
http://zmed.org/C10/C10.314/C10.314.500
ZMed

33. Food: Contaminated Bivalve Shellfish, Salads, Fresh Fruits And Vegetables, Water
myelinolysis, CPM, pontine, images, MRI, hepatitis, findings, reports, infant,CMV, diagnosis, extrapontine myelinolysis, central pontine, pons.
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34. Intenal Medicine Contents Vol.39 No.11
Studies Abstract. Slowly Progressive Dystonia Following Central Pontineand extrapontine myelinolysis Abstract; Bilirubin Adsorption
http://www.naika.or.jp/im/im39/im3911.html

35. Central Pontine Myelinolysis : An Iatrogenic Sequelae Of Hyponatraemia Managemen
His hyponatraemia was corrected, yet he deteriorated and died. CT showedpontine and extrapontine myelinolysis which was confirmed on autopsy.
http://medind.nic.in/imvw/imvw10815.html
Extracted from IndMED Joshi SR; Deshpande AK; Shah SC. Central pontine myelinolysis : an iatrogenic sequelae of hyponatraemia management ? The Indian Practitioner. 1997 Jan; 50(1): 61-7 ABSTRACT: A 45 year old male alcoholic in an unconscious state with abnormal posture had hyperreflexia with extensor plantars. His hyponatraemia was corrected, yet he deteriorated and died. C T showed pontine and extrapontine myelinolysis which was confirmed on autopsy. This highlights the need for careful management of severe hyponatraemia and the role of gradual correction for the same. (The Ind. Pract. 1997; 50(1): 61-67). KEYWORDS: Myelinolysis, Central Pontine/DI; Hyponatremia/DT; Adrenal Cortex Hormones/DE; Data Interpretation, Statistical; Human; Male; Middle Age; Case Report References: 19 Record Identifier: NI203551

36. Royal Hospital For Neuro-disability
Go M. Amino A. Shindo K. Tsunoda S. Shiozawa Z. A case of central pontine myelinolysisand extrapontine myelinolysis during rapid correction of hypernatremia.
http://www.rhn.org.uk/doc.asp?docId=300&catId=257

37. Critical Care Forum | Search Results Winnock_S In Author
6. Diagnosis of extrapontine myelinolysis preceding central pontine myelinolysisArmand JP, Dousset V, Winnock S, Viaud B, Berge J, Caillé JM J Radiol 1995
http://ccforum.com/search/results.asp?db=pm&terms=Winnock_S&field=AU

38. CML-Line: Monatsübersicht
19. Central and extrapontine myelinolysis following allogeneic peripheralhaematopoietic progenitor cell transplantation. Favourable
http://www.cml-online.de/cgi-bin/PubMed/monthview?month=200308

39. UCSF - Neuroradiology Interesting Case: December, 2001
extrapontine myelinolysis (requires an appropriate clinical context; oftenassociated with central pontine myelinolysis). Discussion. Background.
http://www.neurorad.ucsf.edu/previouscases/12012001.html
Excerpted from:
Thieme Publishing's

"Teaching Atlas of Brain Imaging"
UCSF Attendings
Nancy J. Fischbein MD
William Dillon MD , and A. James Barkovich MD
167 cases, over 1000 figures at $139.00.
Interesting Cases
Clinical Presentation
Six months prior to presentation, this 13 year old girl developed fatigue and weight loss. She then presented with a generalized seizure and lapsed into coma for three days. Upon awakening, she was disoriented and inappropriate. An MR scan was obtained. Fig A Fig B Fig C Fig D
Pearls
  • Reversibility of T2-prolonging lesions has been documented, suggesting that they represent areas of edema and possibly microinfarction.
  • The so-called lupus anticoagulant (an antiphospholipid antibody) has a high association with cerebrovascular accidents and venous sinus thrombosis.
    Pitfalls
  • No specific imaging finding is diagnostic of neuropsychiatric lupus.
  • Imaging findings do not necessarily correlate with severity of clinical manifestations.
    Radiologic Findings
    An axial proton density-weighted image (Fig. A ) and a coronal FLAIR image (Fig.
  • 40. Untitled Document
    Læger 1988; 150 17725. 5. Karp BI, Laureno R. Pontine and extrapontine myelinolysisa neurologic disorder following rapid correction of hyponatremia.
    http://www.dadlnet.dk/ufl/ufl9930/v_p/28395.htm
    KASUISTIK Sygehistorie
    Der var sufficient respiration, BT var 280/150 mmHg, og der var normale pupiller med sparsom lysreaktion. Der blev ved modtagelsen givet Stesolid-suppositorium 10 mg 2 uden effekt efterfulgt af injektion med diazepam 10 mg Fig. 1
    Fig. 1.
    Diskussion
    D P-Na Fig. 2
    Fig. 2.
    Summary
    Seizures in a patient with polydipsia and severe hyponatraemia. A case of a 40-year-old psychiatric patient is reported. Primarily, he was thought to have epileptic seizures, but demonstrated acute symptoms of severe hyponatraemia, plasma sodium was 106 mmol/l. Treatment was initiated with hypertonic saline until regression of symptoms, followed by slow correction of serum sodium to subnormal level. The patients outcome was good. This treatment is discussed focusing on the importance of an immediate onset, despite that the cause of hyponatraemia may be unknown. Reprints:
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