1. Epstein-Barr Virus Fact sheet from the Centers for Disease Control. http://www.cdc.gov/ncidod/diseases/ebv.htm

National Center for Infectious Diseases Epstein-Barr Virus and Infectious Mononucleosis DISEASE INFORMATION Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis

2. Epstein-Barr Virus - A Teenage Girl's Story To Offer Support To Others A teenage girl's story of epsteinbarr virus and how she is coping with it. Site offers a message board for others to tell their story of Eptein-Barr Virus or Chronic Fatigue Syndrome. This web http://www.epstein-barr-virus.com/

We are currently have completed the creation of a new message board Welcome to my site. This web site is for all who have been diagnosed with Epstein-Barr Virus or Chronic Fatique Syndrome Please feel free to look around and participate in our message board. If you enjoy what you see here, please recommend our site to a friend. -Kelly kelly@epstein-barr-virus.com

3. Epstein-Barr Virus-Key Text Key text Kissing the epsteinbarr virus goodbye? Published by Glandular fever, a common disease in teenagers, is caused by the epstein-barr virus. http://www.science.org.au/nova/026/026key.htm

Key text Kissing the Epstein-Barr virus goodbye? Published by Australian Academy of Science Sponsored by Glandular fever, a common disease in teenagers, is caused by the Epstein-Barr virus. Australian research on the Epstein-Barr virus has led to a glandular fever vaccine, which is currently being trialled. You will get more from this topic if you have mastered the basics of the immune system Printer-friendly version of complete topic Like most good things in life, kissing can be hazardous to your health. Pucker up to someone and you risk infection with the Epstein-Barr virus, which causes glandular fever and other nasty diseases. But we might not have to give up kissing just yet. A vaccine currently under development in Australian laboratories could help limit the dangers posed by this sometimes deadly virus. How was the virus discovered? In 1961, a surgeon working in Uganda, Denis Burkitt, presented the results of his research to staff at the Middlesex Hospital Medical School in Britain. He reported that the incidence of a certain tumour in African children had a geographic distribution corresponding to rainfall and temperature patterns. The disease, which affects about 8 in every 100,000 children in parts of Africa and Papua New Guinea, quickly became known as Burkitt’s lymphoma. The influence of climate on its incidence seemed to suggest that some biological factor was involved. Three researchers, M.A. Epstein, Y.M. Barr and B.G. Achong, immediately began looking for possible cancer-causing viruses in samples of the tumour sent from Uganda to Britain.

4. Hardin MD : Epstein-Barr Virus From the University of Iowa's Hardin MD, Internet sources on xxxxx. epsteinbarr virus. A Hardin MD Just Plain Links Page epstein-barr virus. Australian Academy of Science. epstein-barr virus http://www.lib.uiowa.edu/hardin/md/ebv.html

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5. Epstein-Barr Virus is the short name for epsteinbarr virus infection, also called Mononucleosis, "Mono " and An increased incidence of epstein-barr virus infection and lymphoproliferative disorder in http://www.classkids.org/library/classqa/ebv.htm

Question: I was a living donor for my son and I tested positive for EBV. So far, our son has tested negative and sometimes borderline positive for EBV. He had IV ganciclovir for 100 days post-transplant and is now on oral acyclovir four times a day for a year. How long do we need to be concerned that he may get full blown EBV, and what will that mean to him medically if he does? Answer: EBV is the short name for Epstein-Barr Virus infection, also called Mononucleosis, "Mono," and the "kissing disease." This virus is a member of the family of Herpes viruses that includes Herpes Simplex, which causes "cold sores" on the lips and mouth as well as genital Herpes; Herpes Zoster which causes Chicken Pox and Shingles; and CMV or cytomegalovirus, a virus that commonly infects post-transplant patients. About 85% of adult Americans will test "positive" for EBV antibodies, which means they have been exposed to the disease in the past. All of the diseases in the Herpes family share the common element that the infection can occur multiple times. This process is called "reactivation." It happens because the body doesn’t really eliminate the virus; rather the virus becomes dormant in cells, only to reemerge at a later date. Since the virus is not eliminated, organs from anyone who has ever been exposed to EBV can transmit the virus to the recipient.

6. Epstein-Barr Virus National Center for Infectious Diseases epsteinbarr virus and Infectious Mononucleosis, DISEASE INFORMATION. epstein-barr virus, frequently http://www.cdc.gov/node.do/id/0900f3ec80006e51

National Center for Infectious Diseases Epstein-Barr Virus and Infectious Mononucleosis DISEASE INFORMATION Epstein-Barr virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious mononucleosis are fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. Heart problems or involvement of the central nervous system occurs only rarely, and infectious mononucleosis is almost never fatal. There are no known associations between active EBV infection and problems during pregnancy, such as miscarriages or birth defects. Although the symptoms of infectious mononucleosis

7. Chronic Fatigue Possibly Related To Epstein-Barr Virus -- Nevada Chronic Fatigue Possibly Related to epsteinbarr virus Nevada. Persisting illness and fatigue in adults with evidence of epstein-barr virus infection. http://www.cdc.gov/mmwr/preview/mmwrhtml/00000740.htm

Chronic Fatigue Possibly Related to Epstein-Barr Virus Nevada From November 1984 through August 1985, approximately 90 patients evaluated for persistent fatigue were diagnosed as having chronic Epstein-Barr virus (CEBV) disease by a two-physician community internal medicine practice near Lake Tahoe, Nevada. The diagnoses were made by detecting antibody to the diffuse (EA-D) or the restricted (EA-R) components of early antigen of EBV, as suggested by two recent studies (1,2). Because of controversy about whether CEBV disease exists, two serologic studies were conducted to evaluate whether a syndrome of chronic fatigue could be statistically associated with a specific pattern of antibody titers against EBV. Fifteen "case" patients, felt to be the most likely to have CEBV, were identified by interviewing 134 of the 139 patients tested for EBV serology in the internal medicine practice between January 1, and August 20, 1985. By definition, these patients had persistent or relapsing unexplained fatigue for at least 2 months, which forced them to stop usual daily activities for at least 2 weeks. Other less universal symptoms included intermittent low-grade fever, sore throat, myalgias, arthralgias, and headaches. All 15 patients were white; 13 were female. The median age was 40 years (range 13-52 years). In the first serologic study, the 15 patients were compared with 118 of the 119 patients who had serologic testing for EBV (the serologic test results on one patient were not available). All 118 of these patients were white; 79 (66.9%) were female. The median age was 36 years (range 10-71 years). The case patients were more likely to have reciprocal EA-D titers of 160 or higher (45.5%, compared with 11.6%; p = 0.014) and EBV viral capsid antigen IgG (VCA-IgG) 160 or greater (80.0%, compared with 51.7%; p = 0.033) in the first serum tested. No evidence of acute EBV infection, manifested by positive IgM titers to VCA, was detected in either the cases or the others tested.

8. Epstein Barr Virus-Useful Sites Mononucleosis (Mayo Clinic, USA). Infectious mononucleosis (also known as glandular fever) is caused by the epsteinbarr virus. This http://www.science.org.au/nova/026/026sit.htm

Kissing the Eppstein-Barr virus goodbye? Useful sites Published by Australian Academy of Science Sponsored by Printer-friendly version of complete topic Viruses: a view from the textbooks (CSIRO Australia) Gives a good overview of viruses. It includes short sections on classification, detection, vaccines and the importance of mutation. The Ras gene and cancer (Access Excellence, USA) Describes how a class of virus contains an oncogene that causes the development of tumours in humans. A similar situation occurs in Burkitt's lymphoma, but with a different virus and different oncogene. http://www.accessexcellence.org/AB/BA/Ras_Gene_and_Cancer.html Mononucleosis (Mayo Clinic, USA) Infectious mononucleosis (also known as glandular fever) is caused by the Epstein-Barr virus. This clinical description includes symptoms, diagnosis and self-care. http://www.mayoclinic.com/findinformation/diseasesandconditions/invoke.cfm?id=DS00352 The following sites contain information about infectious mononucleosis and Burkitt's lymphoma: Epstein-Barr virus and infectious mononucleosis (Centers for Disease Control and Prevention, USA)

9. Epstein-Barr Virus epsteinbarr virus. epstein-barr virus ( EBV), herpesvirus that is the major cause of infectious mononucleosis and Dan Rather)A versatile virus epstein-barr virus displays a few new http://www.infoplease.com/ce6/sci/A0817520.html

HOTWORDS CITE PRINT EMAIL in All Infoplease Almanacs Biographies Dictionary Encyclopedia Home Almanacs Atlas Dictionary ... D-Day Infoplease Tools Periodic Table Conversion Tool Perpetual Calendar Year by Year ... Site Map Also from Infoplease Search Infoplease Info search tips Search Biographies Bio search tips Encyclopedia Epstein-Barr virus Epstein-Barr virus (EBV), herpesvirus that is the major cause of infectious mononucleosis and is associated with a number of cancers, particularly lymphomas in immunosuppressed persons, including persons with AIDS. Epstein-Barr is a ubiquitous virus, so common that it has been difficult to determine whether it is the cause of certain diseases or whether it is simply there as an artifact. In Third World nations, most children are infected with EBV; in most industrialized nations, about 50% of the people are infected. Research has found that all of the lymphomas associated with AIDS and most lymphomas in other immunocompromised persons are connected with latent EBV infection. EBV has been found in biopsy tissue of patients with Hodgkin's disease , breast cancer, and some smooth muscle tumors. EBV also was formerly suspected as the cause of

10. Epstein-Barr Virus This page contains notes on epsteinbarr virus EPSTEIN-BARR_VIRUS. PROPERTIES. member of the herpesvirus family. ds DNA enveloped virus. nucleocapsid 100 nm in diameter, with 162 capsomers http://www.virology-online.com/viruses/EBV.htm

Herpesviruses Slide Set EPSTEIN-BARR_VIRUS PROPERTIES member of the herpesvirus family ds DNA enveloped virus nucleocapsid 100 nm in diameter, with 162 capsomers membrane is derived by budding of immature particles through cell membrane and is required for infectivity. genome is a linear ds DNA molecule with 172 kbp the viral genome does not normally integrate into the cellular DNA but forms circular episomes which reside in the nucleus. the genome is large enough to code for 100 - 200 proteins but only a few have been identified. The proteins characterized thus far fall into the following groups : A._Latent_proteins 1. EB viral nuclear antigen complex (EBNA) - EBNA is now known to be a complex of at least 6 proteins ie. EBNA 1-6. Their functions have yet to be understood but EBNA 1 is thought to be essential for the maintenance of the episomal state of EBV in infected cells and binds to the origin of replication. EBNA 1 is expressed in all known virus carrying cells, but its expression may be lost when a lytic cycle ensues. EBNA 2 has two phenotypes, A and B, strain A, which is found mainly in Caucasians, is more efficient in immortalizing B lymphocytes than strain B, which is mainly found in Africa. However, neither strains have any specific disease association. 2. Latent membrane protein (LMP)

11. Epstein-Barr Virus. epsteinbarr virus. Pathology. epstein-barr virus (EBV) is a curious virus, affecting a surprisingly large number of the population (somewhere around 20%). http://www.diseasedir.org.uk/infect/vir02.htm

Epstein-Barr Virus. Disease type: Viral infection. Figure V.02.01 - The EBV attaches to the outside of the cell, and is internalised by the cell. Once inside the virus releases its DNA content, which enters the nucleus and integrates into the hosts DNA. The viral proteins will then be expressed, to begin the formation of new virus. Pathology With EBV this process is not 100% effective, and a small population of EBV +ve cells will remain. This gives rise to life-long infection. Once EBV has been caught, it cannot be removed. Figure V.02.03 - Translocation of EBV through the genome. This erroneous copying can lead to cancer. Aetiology EBV by itself does not cause disease. But its constant gene translocations can. B cells, of the immune system, will secrete Antibody at a constant level throughout the cells life-span. B cells can become cancerous if a oncogene is placed next to the Antibody gene. Antibodies are produced in great excess, and as the oncogene is next door to the antibody, it too will be produced in excess. The Oncogene will result in a leukemia. EBV has been linked positively with the incidence of Hodgkins disease, Burkitts Lymphoma, and Nasophangeal carcinoma, to name but a few. Figure V.02.02 -

12. Txt001lyb: Epstein-Barr Virus Infection: Basis Of Malignancy And Potential For T Epstein–Barr virus infection basis of malignancy and potential for therapy. Epstein–Barr virus (EBV) is a member of the Lymphocryptovirus genus. http://www-ermm.cbcu.cam.ac.uk/01003842h.htm

Expert Reviews in Molecular Medicine: http://www-ermm.cbcu.cam.ac.uk Accession information: (01)00384-2h.htm (shortcode: txt001lyb); 15 November 2001 Reprint/PDF version How to cite this article Paul G. Murray and Lawrence S. Young Author contact details Lymphocryptovirus genus. These viruses are closely related members of the gamma herpesvirus family and are similar to each other with respect to genomic structure and gene organisation. The EBV genome is composed of linear, double-stranded DNA, which is approximately 172 kb in length (see Fig. 1a; ), and regions of the EBV genome have become known by their position on a Bam HI restriction endonuclease map of the genome (see Fig. 1b EBV is orally transmitted and infectious virus can be detected in oropharyngeal secretions from infectious mononucleosis (IM) patients, from immunosuppressed patients and, at lower levels, from healthy EBV-seropositive individuals (Ref. ). EBV enters B cells by interaction of the major viral glycoprotein gp350/220 with the complement receptor (CR2/CD21, which is the receptor for complement component C3d). The penetration of B cells by EBV also involves the viral glycoproteins gp25 (gL) and gp42/38 in a complex with viral gp85 (gH). This complex mediates an interaction between EBV and major histocompatibility complex (MHC) class II molecules, which serve as a co-receptor for virus entry into B cells (Ref. Crosslinking of CD21 activates B cells from their resting state. Some of the immediate effects that occur simply from this binding event include Lck activation and calcium (Ca

13. Symmetry Herbal And Health WebStore Help and Information on epsteinbarr virus including alternative herbal and nutritional healing choices. epstein-barr virus (EBV) is a condition that has become widespread in the USA The epstein-barr virus ( EBV), a member of the herpes virus family that is also the http://www.go-symmetry.com/epstein-barr.htm

About us Serving the Internet since The go-symmetry.com website is being remodeled click here - if you have a Question click here - to place an Order ... Free - " The Secrets To Longevity " The name Symmetry was chosen because it means " beauty resulting from balanced or harmonious arrangement ", and this describes our Herbal and Nutritional supplements. All of our products are manufactured with the most advanced techniques and under stringent guidelines to ensure that you get the freshest, purest, and best quality product possible. Through research, education, and a sincere concern for planet Earth, you, and your family's health, joy, and well being. Symmetry products are not sold in Stores All information presented on these web pages is not meant to diagnose, prescribe, or to administer to any physical ailments. In all matters related to your health please contact a qualified, licensed practitioner.

14. Epstein-Barr Virus (EBV) .EpsteiinBarr Virus (EBV); from Pacific West Botanicals Therapeutic Chart.Offering 276 select wildcrafted medicinal herbs, tinctures, salves, oils, resins and planting seed. herpes-like virus with both DNA and capsid http://www.geocities.com/lorenzoherbs/Epstein_Barr_Virus.html

Epstein-Barr Virus (EBV) A large, ubiquitous, and normally benign, herpes-like virus with both DNA and capsid. Milk Thistle with Red Root See also Cytomegalovirus Immunologic next back ... chart

15. MedlinePlus Medical Encyclopedia: Epstein-Barr Virus Test epsteinbarr virus test. Definition Return to top. This is a blood test used to detect antibodies to the epstein-barr virus (EBV) antigens. http://www.nlm.nih.gov/medlineplus/ency/article/003513.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Epstein-Barr virus test Contents of this page: Illustrations Alternative names Definition How the test is performed ... Special considerations Illustrations Blood test Alternative names Return to top EBV antibody test; Monospot; Heterophile agglutination test Definition Return to top This is a blood test used to detect antibodies to the Epstein-Barr virus ( EBV ) antigens. How the test is performed Return to top Blood is drawn from a vein on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding. For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.

16. Epstein-Barr Virus Information Diseases Database epsteinbarr virus Herpes virus 4 Herpesvirus 4, human EBV, Disease Database Information Sponsors Contact Previous Page. epstein-barr virus Information. 4 synonyms or equivalents were found. epstein-barr virus. aka/or. Herpes virus 4 http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=29103

17. Epstein-Barr Virus Infections epsteinbarr virus Infections. broader Herpesviridae Infections. Teaching Materials; Patient Education; epstein-barr virus Infections;. http://omni.ac.uk/browse/mesh/detail/C0149678L0159462.html

low graphics Epstein-Barr Virus Infections broader: Herpesviridae Infections other: Bell Palsy Chickenpox Cytomegalovirus Infections Herpes Simplex ... Warts narrower: Burkitt Lymphoma Infectious Mononucleosis Epstein-Barr This interactive tutorial on Epstein-Barr virus has been produced by the Patient Education Institute, and is made available on the Web by the National Library of Medicine MEDLINEplus service. The tutorial provides background information on Epstein-Barr virus and covers the immune system, infectious mononucleosis, symptoms, diagnosis, and treatment. Viewing this tutorial requires Flash plug-in. Teaching Materials Patient Education Epstein-Barr Virus Infections Last modified: 27 May 2004

18. Epstein-Barr Virus Test epsteinbarr virus test. Definition. The Antibodies can be detected against several components of the epstein-barr virus (EBV). These http://www.healthatoz.com/healthatoz/Atoz/ency/epstein-barr_virus_test.html

Encyclopedia Index E Home Encyclopedia Encyclopedia Index E Epstein-Barr virus test Definition The Epstein-Barr virus test is a blood test, or group of tests, to determine the presence or absence of antibodies in the blood stream directed against proteins of the Epstein-Barr virus, the cause of infectious mononucleosis Purpose The test is primarily used to detect whether first time infection (called primary infection) with the Epstein-Barr virus is currently occurring, or has occurred within a short period of time. The pattern of the antibodies detected can, however, tell if the person has never been infected with the Epstein-Barr virus, or if the infection occurred in the more distant past. These tests are mostly utilized in the diagnosis of Epstein-Barr virus-associated infectious mononucleosis when the more common diagnostic test, the heterophile antibody, is negative, or in situations where the infection is manifesting unusual symptoms. Therefore, the tests are often not needed in a situation where a doctor believes that a person has mononucleosis and the heterophile test (also called the monospot test) is positive. In addition, Epstein-Barr virus testing is usually not needed in the evaluation of a patient who has long-lasting

19. EMedicine - Mononucleosis And Epstein-Barr Virus Infection : Article By Glenna B Mononucleosis and epsteinbarr virus Infection. Cheeseman SH, Henle W, Rubin RH, et al epstein-barr virus infection in renal transplant recipients. http://www.emedicine.com/ped/topic705.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Infectious Diseases Mononucleosis and Epstein-Barr Virus Infection Last Updated: July 8, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: EBV, acute infectious mononucleosis, infectious mononucleosis, mono, human herpesvirus 4, HHV-4, kissing disease AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Glenna B Winnie, MD , Director, Division of Pulmonology, Associate Professor, Department of Pediatrics, University of Pittsburgh and Children's Hospital of Pittsburgh Glenna B Winnie, MD, is a member of the following medical societies: American Academy of Pediatrics American College of Physician Executives American Lung Association American Society for Microbiology ... American Thoracic Society , and Society for Pediatric Research Editor(s): Rosemary Johann-Liang, MD

20. Epstein-Barr Virus Primary infection of epsteinbarr virus (EBV), which is primarily transmitted by saliva, actively replicates in the epithelial cells of the oropharynx and can http://www.uq.edu.au/vdu/EBV.htm

This page is a compilation of content from Andrew Brooks who studied at James Cook University (no wat St Jude Children's Research Hospital)and Ray's Virology Homepage created by Dr Ray Baumann from the University of Mississippi Medical Center. Introduction EBV Morphology Glycoproteins Involved in Attachment and Entry into Cells Latent Infection ... References Introduction - first description of Burkitt's lymphoma in the malaria belt of east Africa. - Epstein and Barr isolate continuous cell lines from Burkitt lymphoma cells; initial description of a herpesvirus present in these cells. - EBV demonstrated as the etiological agent of infectious mononucleosis. - EBV shown to immortalize lymphocytes in culture; EBV can immortalize marmoset cells and cause tumors in non-human primates. Primary infection of Epstein-Barr virus (EBV), which is primarily transmitted by saliva, actively replicates in the epithelial cells of the oropharynx and can subsequently infect recirculating B lymphocytes which may lead to acute infectious mononucleosis (glandular fever). Infectious mononucleosis is a benign lymphoproliferative disease that is usually seen in children, although most cases of EBV infection occur in early childhood and have no symptoms. It is characterised by transient immunosuppression and an unusual expansion of atypical lymphocytes, the majority of which are not B cells but CD8

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