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         Empty Sella Syndrome:     more detail
  1. The Official Patient's Sourcebook on Empty Sella Syndrome: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2003-04-08
  2. Empty sella syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Scott, MS, CGC Polzin, 2005

1. NINDS Empty Sella Syndrome Information Page
empty sella syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). More about empty sella syndrome,
http://www.ninds.nih.gov/health_and_medical/disorders/emptysella.htm
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Table of Contents (click to jump to sections) What is Empty Sella Syndrome ?
Is there any treatment?

What is the prognosis?
What research is being done? ... Organizations What is Empty Sella Syndrome ? Empty Sella Syndrome (ESS) is a disorder that involves the sella turica , a bony structure at the base of the brain that surrounds and protects the pituitary gland. ESS is a condition that is often discovered during tests for pituitary disorders, when radiological imaging of the pituitary gland reveals a sella turica that appears to be empty. There are two types of ESS: primary and secondary. Primary ESS happens when a small anatomical defect above the pituitary gland increases pressure in the sella turica and causes the gland to flatten out along the interior walls of the sella turica cavity. Primary ESS is associated with obesity and high blood pressure in women. The disorder sometimes results in a build-up of fluid pressure inside the skull and the pituitary gland may be smaller than usual.

2. What Is Empty Sella Syndrome? - Endocrinology Health Guide
empty sella syndrome is common in women who are overweight or have high blood pressure. This health guide deals soley on this disorder. empty sella syndrome.
http://www.umm.edu/endocrin/sella.htm

Endocrinology Health Guide...
Pituitary Gland Disorders... Pituitary Tumors Acromegaly ... Glossary
Related Resources Within UMM Endocrinology Joslin Diabetes Center School of Medicine Endocrinology Site Endocrinology Health Guide
Empty Sella Syndrome
What is empty sella syndrome?
Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal or small in size.
What are the symptoms of empty sella syndrome?
Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose.
How is empty sella syndrome diagnosed?
In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
  • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray

3. The Methodist Hospital - Data Not Available
Methodist Health Care System explains what this syndrome is, the symptoms, diagnosis and its treatment.
http://www.methodisthealth.com/endocrin/sella.htm
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4. Empty Sella Syndrome
a CHORUS notecard document about empty sella syndrome Disclaimer. Feedback. Search. empty sella syndrome. etiology. idiopathic xray findings sella normal or increased. intrasellar herniation
http://chorus.rad.mcw.edu/doc/00517.html
CHORUS Collaborative Hypertext of Radiology Nervous system
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Search
empty sella syndrome
etiology
  • idiopathic
    • most commonly reported in middle-aged obese women (a/w DM, HTN, normal pituitary function)
  • secondary
  • familial (very rare)
xray findings:
  • sella normal or increased
  • intrasellar herniation of subarachnoid space
  • symptoms:
    • headache, visual disorders
    • +/- decreased pituitary function
    • CSF rhinorrhea
    Charles E. Kahn, Jr., MD - 2 February 1995
    Last updated 26 May 2004

    Medical College of Wisconsin
  • 5. Pituitary Network Association - Disorders - Empty Sella Syndrome
    empty sella syndrome. empty sella syndrome is a radiological finding where spinal fluid is found within the Some patients have empty sella syndrome as a result of other processes
    http://www.pituitary.com/disorders/emptysellasyndrome.php
    Empty Sella Syndrome Empty sella syndrome is a radiological finding where spinal fluid is found within the space created for the pituitary. The most common cause is a large opening in the diaphragma sellae, a membrane which sits on top of the pituitary and protects it in its socket within the bones at the base of the skull. When this opening is large, the spinal fluid pressure is transmitted to the pituitary and flattens it out within the sella. Generally, in this situation, pituitary function is normal, but a number of patients have headaches, mild hyperprolactinemia, galactorrhea, and irregular menses. In most cases, however, the pituitary functions normally as evidenced by normal thyroid functions, normal tests of adrenal function, normal somatomedin-C levels, and regular menses. Some patients have empty sella syndrome as a result of other processes such as neurosarcoidosis pituitary tumors that have degenerated, etc. Rare patients have a congenital empty sella and a coexisting pituitary tumor. Symptoms
    • unusual facial features
    • increased bone density
    • headaches
    • vision problems
    Diagnosis
  • x-ray
  • CT (CAT) scan
  • Magnetic resonance imaging (MRI) Treatment Unless the disorder results in other medical problems, treatment is symptomatic and supportive. In some cases, surgery may be needed.
  • 6. MedlinePlus Medical Encyclopedia: Empty Sella Syndrome
    is referred to as empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical is called secondary empty sella syndrome. Primary empty sella syndrome is most
    http://www.nlm.nih.gov/medlineplus/ency/article/000349.htm
    @import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation
    Medical Encyclopedia
    Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z
    Empty sella syndrome
    Contents of this page:
    Illustrations
    The pituitary gland Definition Return to top Empty sella syndrome is the absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that normally partly surrounds the gland. Causes, incidence, and risk factors Return to top The pituitary gland is a small gland located at the base of the brain. It makes several hormones that control the function of other glands in the body, including the thyroid, the adrenal glands, and the ovaries or testes. The pituitary gland is partly surrounded by a bony structure called the sella turcica ("Turkish saddle"). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury such as head trauma or an event such as surgery or radiation therapy, the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding during

    7. Empty Sella
    empty sella syndrome Dr. M. Balaganapathy, Senior Neurosurgical Registrar, Apollo Hospitals, Chennai India. Empty sella is a radiological diagnosis based on CT or MR investigation. and the diagnosis is made by chance. empty sella syndrome is the pathological variant of a radio logically verified
    http://www.thamburaj.com/empty_sella.htm
    Empty sella syndrome Dr. M. Balaganapathy, Senior Neurosurgical Registrar Apollo Hospitals, Chennai , India. Empty sella is a radiological diagnosis based on CT or MR investigation. Either a normal sized (empty sella) or enlarge sella (empty enlarged sella) presents partly or totally filled with cerebrospinal fluid. The radiological diagnosis does not mean a pathological situation in every instance. Many patients present without specific symptoms and the diagnosis is made by chance. Empty sella syndrome is the pathological variant of a radio logically verified empty sella. Primary empty sella is an idiopathic form of an empty sella which occurs in the absence of prior pituitary surgery or radiation therapy or medication with DOPA agonists. Secondary empty sella occurs as a result of surgical resection or irradiation of a sellar expansion. Anatomy: The disphragma sellae normally forms a circular fold that constitutes a roof for the sella turcica with only a small central opening for the passage of the pituitary stalk. Busch in 1951 performed an autopsy study of 788 subjects without known pituitary disease. In 38.4% he found a complete covering of pituitary gland by the diaphragm. He observed an empty sella in 5.5%. Other studies described significant defects in the sellar diaphragm in 22% to 72% of cases. These defects were frequently accompanied by intrasellar extension of subarachnoid space and downward displacement of the optic chiasm.

    8. NORD - National Organization For Rare Disorders, Inc.
    The primary from of empty sella syndrome is a rare inherited disorder of the brain that is transmitted as an autosomal Organizations related to empty sella syndrome. Genetic Alliance
    http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Empty Sella S

    9. ► Empty-sella Syndrome
    Emptysella syndrome. When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as the empty sella syndrome.
    http://www.umm.edu/ency/article/000349.htm
    Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English)
    Toggle English Spanish
    Empty-sella syndrome
    Overview Symptoms Treatment Prevention Definition: Absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that partly surrounds the gland.
    Causes, incidence, and risk factors: The pituitary gland is a small, oval gland at the base of the brain. It makes several hormones that control the function of other glands in the body including the thyroid gland, adrenal glands, and gonads (ovaries or testes). The pituitary gland is partly surrounded by a bony structure called the sella turcica (Turkish saddle). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as the empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury (e.g., surgery, head trauma, radiation therapy), the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding on radiological imaging of the brain. Pituitary function is usually normal, and patients do not have any symptoms. The hormone prolactin is mildly elevated in 10-15 % of patients, and the elevated prolactin may interfere with normal function of the testes or ovaries. Medications that suppress prolactin production (e.g., bromocriptine) are effective in correcting the problem.

    10. Pituitary Network Association - Disorders - Empty Sella Syndrome
    empty sella syndrome is a radiological finding where spinal fluid is found within the space created for the pituitary.
    http://www.pituitary.org/disorders/emptysellasyndrome.php
    Empty Sella Syndrome Empty sella syndrome is a radiological finding where spinal fluid is found within the space created for the pituitary. The most common cause is a large opening in the diaphragma sellae, a membrane which sits on top of the pituitary and protects it in its socket within the bones at the base of the skull. When this opening is large, the spinal fluid pressure is transmitted to the pituitary and flattens it out within the sella. Generally, in this situation, pituitary function is normal, but a number of patients have headaches, mild hyperprolactinemia, galactorrhea, and irregular menses. In most cases, however, the pituitary functions normally as evidenced by normal thyroid functions, normal tests of adrenal function, normal somatomedin-C levels, and regular menses. Some patients have empty sella syndrome as a result of other processes such as neurosarcoidosis pituitary tumors that have degenerated, etc. Rare patients have a congenital empty sella and a coexisting pituitary tumor. Symptoms
    • unusual facial features
    • increased bone density
    • headaches
    • vision problems
    Diagnosis
  • x-ray
  • CT (CAT) scan
  • Magnetic resonance imaging (MRI) Treatment Unless the disorder results in other medical problems, treatment is symptomatic and supportive. In some cases, surgery may be needed.
  • 11. Medical Encyclopedia: Empty Sella Syndrome (Print Version)
    Medical Encyclopedia empty sella syndrome. Primary empty sella syndrome is most often an incidental finding during radiological imaging of the brain.
    http://www.nlm.nih.gov/medlineplus/print/ency/article/000349.htm
    To print this page, use the print option from your browser.
    To close this window, click on the "x" in the upper right hand corner of the window.
    Medical Encyclopedia: Empty sella syndrome
    URL of this page: http://www.nlm.nih.gov/medlineplus/ency/article/000349.htm Definition Empty sella syndrome is the absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that normally partly surrounds the gland. Causes, incidence, and risk factors The pituitary gland is a small gland located at the base of the brain. It makes several hormones that control the function of other glands in the body, including the thyroid, the adrenal glands, and the ovaries or testes. The pituitary gland is partly surrounded by a bony structure called the sella turcica ("Turkish saddle"). When the pituitary gland is not visible on CT or MRI scans of the sella turcica, the condition is referred to as empty sella syndrome. Primary empty sella syndrome occurs when a small anatomical defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten out along the walls of the sella. When the sella is empty because the pituitary gland has regressed following an injury such as head trauma or an event such as surgery or radiation therapy, the condition is called secondary empty sella syndrome. Primary empty sella syndrome is most often an incidental finding during radiological imaging of the brain. Pituitary function is usually normal, and patients do not have any symptoms. The hormone prolactin is mildly elevated in 10% to 15 % of patients, and the elevated prolactin may interfere with normal function of the testes or ovaries.

    12. Introduction: Empty Sella Syndrome - WrongDiagnosis.com
    Introduction to empty sella syndrome as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
    http://www.wrongdiagnosis.com/e/empty_sella_syndrome/intro.htm
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    Introduction: Empty Sella Syndrome
    Empty Sella Syndrome: Congenital defect of the brain. Empty Sella Syndrome: Empty sella syndrome is a rare congenital disorder that occurs when an empty space in the brain fills with cerebrospinal fluid as a result of a deformity in the brain. Contents for Empty Sella Syndrome: Footnotes: 1. excerpt from

    13. UAB Health System | Empty Sella Syndrome
    empty sella syndrome. What is empty sella syndrome? empty sella syndrome is common in women who are overweight or have high blood pressure.
    http://www.health.uab.edu/show.asp?durki=19212

    14. THE MERCK MANUAL--SECOND HOME EDITION, Empty Sella Syndrome In Ch. 162, Pituitar
    The Merck Manual of Medical InformationSecond Home Edition Galactorrhea empty sella syndrome. empty sella syndrome. In empty sella syndrome, the sella turcica (the bony People with empty
    http://www.merck.com/pubs/mmanual_home2/sec13/ch162/ch162g.htm

    Section 13. Hormonal Disorders
    Chapter 162. Pituitary Gland Disorders Topics: Introduction Enlargement of the Pituitary Gland Hypopituitarism Central Diabetes Insipidus ... Galactorrhea
    Empty Sella Syndrome
    In empty sella syndrome, the sella turcica (the bony structure at the base of the brain that houses the pituitary gland) enlarges, but the pituitary remains normal-sized or shrinks. People with empty sella syndrome have a defect in the tissue barrier that normally keeps the cerebrospinal fluid around the brain separate from the sella turcica. As a result, cerebrospinal fluid puts increased pressure on the pituitary gland and the walls of the sella turcica. The sella turcica may enlarge, and the pituitary gland may shrink. Empty sella syndrome occurs most often in middle-aged women who are overweight and who have high blood pressure. Less commonly, the condition occurs after pituitary surgery, radiation therapy, or infarction (death) of a pituitary tumor. The empty sella syndrome may produce no symptoms at all and seldom produces serious symptoms. About half of those affected have headaches, and some people have high blood pressure as well. In rare cases, there is leaking of the cerebrospinal fluid from the nose or problems with vision. The empty sella syndrome can be diagnosed by computed tomography (CT) or magnetic resonance imaging (MRI) scanning. Pituitary function is checked to rule out hormone excess or deficiency, but is almost always normal.

    15. Empty Sella Syndrome - Information / Diagnosis / Treatment / Prevention
    home endocrine disorders pituitary empty sella syndrome empty sella syndrome. Information • Diagnosis • Treatment • Prevention.
    http://www.healthcyclopedia.com/endocrine-disorders/pituitary/empty-sella-syndro

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    Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "empty sella syndrome"
    Health News: Search millions of published articles for news on Empty Sella Syndrome Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Empty Sella Email list available to anyone interested in sharing information and/or support for persons affected by this syndrome. Empty Sella Syndrome Methodist Health Care System explains what this syndrome is, the symptoms, diagnosis and its treatment. Empty Sella Syndrome Information sheet compiled by NINDS compiled by NINDS, the National Institute of Neurological Disorders and Stroke.

    16. AllRefer Health - Empty Sella Syndrome
    empty sella syndrome information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, tests, support groups
    http://health.allrefer.com/health/empty-sella-syndrome-info.html
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    You are here : AllRefer.com Health Empty Sella Syndrome
    Empty Sella Syndrome
    Definition
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    Complications ...
    Go To Main Page
    Definition Empty sella syndrome is the absence of the pituitary gland on radiological imaging of the sella turcica, a bony structure that normally partly surrounds the gland.
    The Pituitary Gland The pituitary gland is a small gland located at the base of the brain. It makes several hormones that control the function of other glands in the body, including the thyroid, the adrenal glands, and the ovaries or testes. The pituitary gland is partly surrounded by a bony structure called the sella turcica ("Turkish saddle"). When the pituitary gland is not visible on

    17. AllRefer Health - Empty Sella Syndrome Prognosis (Expectations)
    empty sella syndrome. empty sella syndrome. See all Pictures Images empty sella syndrome Prognosis (Expectations). Primary empty sella
    http://health.allrefer.com/health/empty-sella-syndrome-prognosis.html
    AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia
    You are here : AllRefer.com Health Empty Sella Syndrome : Prognosis of Empty Sella Syndrome
    Empty Sella Syndrome
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    Go To Main Page
    Empty Sella Syndrome Prognosis (Expectations) Primary empty sella syndrome does not have adverse health consequences, and it does not alter life expectancy. The specific cause of pituitary gland injury and the effects of hypopituitarism contribute to the outcome with secondary empty sella syndrome.
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    Calling Your Health Care Provider Topics that might be of interest to you Hypogonadism Hypopituitarism Inhibited Sexual Desire Pituitary Dwarfism ... MRI of the Head Other Topics Erection Problems Menstruation - Absent Review Date : 1/6/2003 Reviewed By : Todd T. Brown, M.D., Division of Endocrinology and Metabolism, Johns Hopkins Hospital, Baltimore, MD. Review provided by VeriMed Healthcare Network.

    18. THE MERCK MANUALSECOND HOME EDITION, Empty Sella Syndrome In Ch.
    empty sella syndrome. empty sella syndrome occurs most often in middleaged women who are overweight and who have high blood pressure.
    http://www.merck.com/mrkshared/mmanual_home2/sec13/ch162/ch162g.jsp

    19. Empty Sella Syndrome
    The primary from of empty sella syndrome is a rare inherited disorder of the brain that is transmitted as an autosomal dominant trait. empty sella syndrome.
    http://www.bchealthguide.org/kbase/nord/nord635.htm
    document.write(''); var hwPrint=1; var hwDocHWID="nord635"; var hwDocTitle="Empty Sella Syndrome"; var hwRank="1"; var hwSectionHWID="nord635"; var hwSectionTitle=""; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="NORD";
    National Organization for Rare Disorders, Inc.
    Empty Sella Syndrome
    Important
    It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
    Synonyms
    • Empty Sella Turcica
    Disorder Subdivisions
    • None
    Related Disorders List
    Information on the following diseases can be found in the Related Disorders section of this report:
    • Achard-Thiers Syndrome Craniopharyngioma Meningioma of the Tuberculum Sella Optic Glioma
    General Discussion
    The primary from of empty sella syndrome is a rare inherited disorder of the brain that is transmitted as an autosomal dominant trait. The disorder is characterized by an empty space filled with cerebrospinal fluid in the sella turcica area of the brain. The area fills with fluid as a result of a defect in the sella diaphragm. Symptoms and findings may include unusual facial features, a highly-arched palate, moderate short stature, increased bone density (osteosclerosis), and normal pituitary function.
    The secondary form of this disorder is caused by another underlying disorder or defect (e.g., surgery, radiation therapy, etc.). In the idiopathic form of the disease, the exact cause in not known. This form of the disorder affects mostly obese, middle-aged women.

    20. Endocrinology - Empty Sella Syndrome
    empty sella syndrome What is empty sella syndrome ? empty sella syndrome is common in women who are overweight or have high blood pressure.
    http://www.stjohnsmercy.org/healthinfo/adult/endocrin/sella.asp
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    Health Information
    Adult Health Endocrine System Printable Version Empty Sella Syndrome What is empty sella syndrome
    Empty sella syndrome is common in women who are overweight or have high blood pressure. Characterized by an enlarged bony structure (sella turcica) that houses the pituitary gland at the base of the brain, the disorders sometimes results in high fluid pressure inside the skull. The pituitary gland is usually normal size or small.
    What are the symptoms of empty sella syndrome
    Each individual may experience symptoms differently. Besides high fluid pressure in the skull, which occurs in about 10 percent of patients, another symptom is a chronically runny nose.
    How is empty sella syndrome diagnosed
    In addition to a complete medical history and medical examination, diagnostic procedures for empty sella syndrome may include:
    • x-ray of the skull computed tomography (CT or CAT scan) - a non-invasive procedure that takes cross-sectional images of the brain or other internal organs; to detect any abnormalities that may not show up on an ordinary x-ray magnetic resonance imaging (MRI) - a non-invasive procedure that produces two-dimensional views of an internal organ or structure, especially the brain or spinal cord

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