81. Ebola Virus - Material Safety Data Sheets (MSDS) SECTION I INFECTIOUS AGENT. NAME ebola virus. SYNONYM OR CROSS REFERENCE African hemorrhagic fever, ebola hemorrhagic fever (EHF), ebola disease, EBO, EBOV. http://www.hc-sc.gc.ca/pphb-dgspsp/msds-ftss/msds53e.html

Material Safety Data Sheets - Index MATERIAL SAFETY DATA SHEET - INFECTIOUS SUBSTANCES SECTION I - INFECTIOUS AGENT NAME: Ebola virus SYNONYM OR CROSS REFERENCE: African hemorrhagic fever, Ebola hemorrhagic fever (EHF), Ebola disease, EBO, EBOV CHARACTERISTICS: Filoviridae ; pleomorphic, 80nm diameter and 970 nm in length ( can be up to 14,000 nm in length), helical nucleocapsid, nonsegmented negative ssRNA, enveloped SECTION II - HEALTH HAZARD PATHOGENICITY: Sudden onset with high fever, malaise, abdominal pain, myalgias, vomiting, diarrhea; maculopapular rash, renal and hepatic involvement and hemorrhagic diathesis; involvement of liver, pancreas, kidney, and to a much less degree the CNS and heart; leukopenia, thrombocytopenia and transaminase elevation; 50%-90% case fatality rate; Subtype EBOV-Reston causes fatal hemorrhagic disease in non -human primates EPIDEMIOLOGY: First recognized in the Sudan and Democratic Rep. of the Congo (formerly Zaire) in 1976 (epidemic involved over 500 cases with at least 350 deaths); second outbreak in the Sudan in 1979; antibodies in 7% of asymptomatic individuals in the epidemic area; third outbreak in Kikwit, Democratic Rep. of the Congo in 1995; fourth outbreak in Uganda in 2000; last outbreak in Gabon/The Republic of the Congo in 2001-2002; four genetically different subtypes: EBOV-Zaire, EBOV-Sudan, EBOV-Ivory Coast and EBOV-Reston (Reston causes disease in non-human primates; however, clinically asymptomatic in humans); two outbreaks of EBOV-Reston in USA 1989, 1996

82. Kenya Town Calm As Officials Play Down Ebola Fears CNN http://cnn.com/2001/WORLD/africa/04/11/health.kenya.reut/index.html

83. CNN.com - Health - Deadly Ebola Outbreak Likely To Last For Months - October 24, CNN http://www.cnn.com/2000/HEALTH/10/24/bc.health.ebola.un.reut/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Deadly Ebola outbreak likely to last for months GENEVA, Switzerland (Reuters) The death toll from Ebola fever in northern Uganda rose to 60 on Tuesday and the outbreak is expected to continue for months, the World Health Organization said. The deaths in Uganda's Gulu province rose from 55 on Monday, and the number of cases reported also rose to 165 from Monday's 160, said Valery Abramov, a spokesman for the Geneva-based United Nations health agency.

84. CNN.com - Ebola Outbreak 'not Contained' - Feb. 19, 2003 UN health officials confirmed on Wednesday that a disease outbreak killing scores of people in the Republic of Congo was ebola and warned that the highly http://www.cnn.com/2003/WORLD/africa/02/19/congo.ebola.ap/

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Ebola outbreak 'not contained' Ebola is spread through bodily fluids and has a two to 21-day incubation period. Story Tools BRAZZAVILLE, Republic of Congo (AP) U.N. health officials confirmed on Wednesday that a disease outbreak killing scores of people in the Republic of Congo was Ebola and warned that the highly lethal haemorrhagic fever could still be spreading. "We're not suggesting that this is over or even contained. We're treating it as an active outbreak," Iain Simpson, a World Health Organization (WHO) spokesman in Geneva, said. So far, 73 people have been infected, of whom 59 have died, according to WHO investigators. Government health officials in the tiny Central African nation report 80 cases with 67 deaths. The Cuvette West region, where the deaths have occurred, has been quarantined by the government since last week. Blood samples drawn from victims in the region tested positive for the Ebola virus, Josef Mboussa, a top official in Republic of Congo's health ministry, said. The disease is one of the world's deadliest, causing rapid death through massive blood loss in up to 90 percent of those infected.

85. Last Ebola Patient In Uganda Leaves Hospital CNN http://cnn.com/2001/HEALTH/01/23/uganda.ebola.ap/index.html

86. CNN - Does Importing Primates Push Ebola Risk Too High? - Apr. 16, 1996 Does importing primates push ebola risk too high? April Reston. Current evidence indicates that humans can t be sickened by ebola Reston. http://www.cnn.com/HEALTH/9604/16/nfm/ebola.levine/

Does importing primates push Ebola risk too high? April 16, 1996 Web posted at: 10:30 p.m. EDT From Correspondent Jeff Levine WASHINGTON (CNN) Army scientists near Washington are studying blood samples from monkeys thought to carry the Ebola virus. If the tests are positive, it will mean the worst for the primates, now being housed at a Texas facility. "Basically, the animals are doomed. At this point, it's reasonable to assume all the animals have been exposed," said Dr. Peter Jahrling of the U.S. Army. The animals, imported from the Philippines, are infected with a strain of the Ebola virus known as Ebola Reston. Current evidence indicates that humans can't be sickened by Ebola Reston. During a 1989 outbreak of the strain at a primate facility in Reston, Virginia, four people were exposed, but didn't get sick. As in Texas, the monkeys in the Virginia outbreak all came from the same exporter. Scientists say Ebola Reston is transmitted through the air. The deadly Ebola Zaire, on the other hand, is spread through blood and other bodily fluids. An outbreak in Zaire last year killed 245 people. "We've been dealing with Ebola Reston for nearly seven years, and in the Ebola Restons we've seen, we do not see illness occur in humans," said Bob Howard, who works at the U.S. Centers for Disease Control.

87. Death Toll Rising From Suspected Ebola In Congo CNN http://cnn.com/2003/HEALTH/conditions/02/18/congo.ebola.reut/index.html

88. New Scientist ebola virus could be synthesised. 1900 17 July 02. The real worry is that bioterrorists could use the method to recreate viruses such as ebola and smallpox. http://www.newscientist.com/news/news.jsp?id=ns99992555

89. CNN.com - Ebola Outbreak Kills 18 In Congo - Nov. 25, 2003 CNN http://cnn.com/2003/HEALTH/conditions/11/25/congo.ebola.reut/index.html

International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Services CNNtoGO Contact Us SEARCH Web CNN.com Ebola outbreak kills 18 in Congo Story Tools BRAZZAVILLE, Congo (Reuters) An outbreak of the deadly Ebola virus has killed 18 people in northwestern Congo Republic, where the disease killed 120 earlier this year, state television said. HEALTH LIBRARY Health Library YOUR E-MAIL ALERTS Ebola virus Democratic Republic of Congo or Create your own Manage alerts What is this? One hundred and sixty-four people have come into contact with the disease around Mbomo, some 700 km (440 miles) northwest of the central African nation's capital Brazzaville and just across the border from Gabon, Tele-Congo said on Monday night. Teams from Congo Republic's health ministry, the World Health Organization and aid agency Medecins Sans Frontieres were in the Mbomo region trying to break the chain of contamination. There is no known cure for Ebola, which is passed on by infected body fluids and kills between 50 and 90 percent of victims depending on the strain. The disease damages blood vessels and can cause bleeding, diarrhea and shock. Its worst outbreak, in 1995, killed more than 250 people in the Democratic Republic of Congo.

90. New Scientist Congo s ebola outbreak passes 100 cases. 1221 04 March 03. Moriniere said scientists have not managed to identify the natural reservoir of the ebola virus. http://www.newscientist.com/news/news.jsp?id=ns99993455

91. Ebola Virus Life Cycle Illustration - Russell Kightley Media ebola Virus LifeCycle Illustration. ebola OUTBREAK in Gabon reported 9 Dec 2001. NEWS on the ebola References on the web ebola AND MARBURG http://www.rkm.com.au/ebola.html

92. WHO Declares Uganda Free Of Ebola Virus CNN http://cnn.com/2001/WORLD/africa/02/28/uganda.ebola.ap/index.html

93. CNN.com - Number Of Ebola Victims Reaches 400; 160 Dead In Uganda - December 8, CNN http://cnn.com/2000/WORLD/africa/12/08/uganda.ebola.ap/index.html

world africa Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Number of Ebola victims reaches 400; 160 dead in Uganda

94. Ebola- Und Marburg-Fieber Translate this page Im September 1976 kam es in der Umgebung der südsudanesischen Städte Maridi und Nzara und in Zaire in der Umgebung des Flusses ebola sowie im Krankenhaus der http://www.netdoktor.de/krankheiten/reisemedizin/ebola_marburg.htm

Suche in NetDoktor NetDoktor.de Startseite Aktuell Nachrichten Features Newsletter Lexikon Krankheiten Symptome Untersuchungen Eingriffe ... Medikamente Themen Asthma Erektile Dysfunktion Herz Neurodermitis ... Alle Themen Service Experten-Rat Teste Dich Selbst Quiz Diskussion ... Selbsthilfe Information Kontakt Impressum NetDoctor.com Ebola- und Marburg-Fieber Andreas Ploch , Arzt Was ist Ebola- und Marburg-Fieber? Viren Welche Symptome treten bei Ebola- und Marburg-Fieber auf? Fieber , begleitet von heftigen Kopf- Gelbfieber Lassa-Fieber , Rift-Valley-Fieber, Dengue-Fieber und Malaria tropica verwechselt werden. Wie stellt der Arzt die Diagnose? mikroskopischen Verfahren gegen die Viren direkt nachzuweisen. Da eine Impfung Quellen Redaktion Dr. med. Katharina Larisch Aktualisierung NETDOKTOR.DE: Startseite AKTUELL: Nachrichten Features Newsletter LEXIKON: Krankheiten Symptome Untersuchungen Eingriffe ... Medikamente THEMEN: Asthma Erektile Dysfunktion Herz Neurodermitis ... Alle Themen SERVICE: Experten-Rat Teste Dich Selbst Quiz Diskussion ... Selbsthilfe INFORMATION: Kontakt Impressum NetDoctor.com Nutzungsbedingungen - Wichtige Informationen The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care or attention by a qualified practitioner. The materials in this web site cannot and should not be used as a basis for diagnosis or choice of treatment. Click here - Conditions for use - Important legal information NetDoktor.de is a trademark

95. Fast, One-shot Ebola Vaccine Developed CNN http://cnn.com/2003/HEALTH/08/06/ebola.vaccine.ap/index.html

96. Ebola Fact Sheet Fact Sheet from the World Health Organization about ebola Haemorrhagic Fever http://www.who.int/inf-fs/en/fact103.html

97. Ebola Spreads From Animals To Hunters: Future Outbreaks May Be Hard To Predict, ebola spreads from animals to hunters. 16 January 2004 HELEN R. PILCHER. Infected gorilla carcasses can spread ebola to people who touch them. © Pierre Rouquet. http://www.nature.com/nsu/040112/040112-12.html

updated at midnight GMT search nature science update advanced search Ebola spreads from animals to hunters Future outbreaks may be hard to predict, tests suggest. 16 January 2004 HELEN R. PILCHER Infected gorilla carcasses can spread Ebola to people who touch them. A genetic analysis of Ebola in central Africa has helped confirm that the disease can spread to people when hunters handle infecetd animal corpses. Eric Leroy at the International Centre for Medical Research in Franceville, Gabon, and colleagues, along with local villagers, noticed an increased number of large animal carcasses in the forest just before one Ebola outbreak in Gabon. When the researchers tested the corpses, most were found to be positive for the Ebola virus. The team then looked at the genetic sequences of viruses in both animal and human victims from five outbreaks that struck Gabon and the Republic of Congo over the past two years . They traced each outbreak from dead animals through to the first human victim and subsequent human victims. Their analysis suggests that the five outbreaks were caused by five distinct Ebola viral strains, rather than by one strain that mutated into different forms. That implies that a new outbreak could pop up anywhere at any time, says Leroy, making future outbreaks very difficult, if not impossible, to predict.

98. CNN.com - Supplies Run Short As Ugandan Authorities Wrestle With Ebola - October CNN http://www.cnn.com/2000/WORLD/africa/10/17/uganda.ebola.02.ap/index.html

world africa Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Supplies run short as Ugandan authorities wrestle with Ebola GULU

99. Fast Vaccine Offers Hope In Battle With Ebola : Similar Vaccines Could Form Part Fast vaccine offers hope in battle with ebola. Similar vaccines could form part of future emergency strategy. ebola outbreaks occur every few years in Africa. http://www.nature.com/nsu/030804/030804-9.html

updated at midnight GMT search nature science update advanced search Fast vaccine offers hope in battle with Ebola Similar vaccines could form part of future emergency strategy. 7 August 2003 This story is from the news section of the journal Nature Ebola outbreaks occur every few years in Africa. High-speed vaccines could help to contain unexpected outbreaks of disease, say US researchers who have developed a fast-acting vaccine against the deadly Ebola virus. The new vaccine, reported in this issue of Nature , gives macaque monkeys protection from Ebola infection only four weeks after a single jab. Previous Ebola vaccines took six months and multiple boosters to confer immunity. Should the vaccine prove safe and effective in humans, this would be fast enough to stop Ebola outbreaks, says lead author Gary Nabel, head of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland. It could also form a template for developing emergency vaccines against unexpected outbreaks of disease, Nabel says. Most vaccines serve only as a preventive measure, because they take too long to produce immunity to be useful once an outbreak has begun. A notable exception is smallpox vaccine, which acts so quickly that it can sometimes stop the disease even after a person has been infected with the virus.

100. Congo Health Minister Disease Outbreak Probably Not Ebola CNN http://cnn.com/2001/WORLD/africa/12/10/congo.outbreak.reut/index.html

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