21. DoctorNDTV.com .... For The Better Health Of Indians diabetic neuropathies are nerve disorders caused by diabetes. diabetic neuropathiesmay be classified as peripheral, autonomic, proximal, and focal. http://www.doctorndtv.com/topics/detailtopics.asp?id=564

22. Penn State Faculty Research Expertise Database (FRED) , Neuralgias.diabetic neuropathies, Painful, Diabetic Neuropathy.......Faculty Research Expertise Database. diabetic neuropathies. http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D003929

23. Images.MD: View Collection section diabetic neuropathies. The results of your search are displayed below. Pathogenesisof diabetic neuropathy. Click here for more detail about this image. http://images.md/users/explore_chapter.asp?ID=ACE0202-13&colID=ACE0202&coltitle=

24. The American Pain Foundation What Is Diabetic Neuropathy? 943422). Bethesda, MD. Vinik, A., et al.,diabetic neuropathies, Diabetes Care, December 1992, pp. 1926-1975. http://www.painfoundation.org/page.asp?file=documents/doc_016.htm&menu=1

25. Adws.info - Diabetes And Nerve Damage diabetic neuropathies The Nerve Damage of Diabetes. On this page diabetic neuropathiescan be classified as peripheral, autonomic, proximal, and focal. http://www.adiabeteswebsite.com/b20.htm

diabetes and nerve damage Advertisement Diabetic Neuropathies: The Nerve Damage of Diabetes On this page: Causes Symptoms Types of Diabetic Neuropathy Neuropathy Affects Nerves Throughout the Body ... For More Information D iabetic neuropathies are a family of nerve disorders caused by diabetes. People with diabetes can, over time, have damage to nerves throughout the body. Neuropathies lead to numbness and sometimes pain and weakness in the hands, arms, feet, and legs. Problems may also occur in every organ system, including the digestive tract, heart, and sex organs. People with diabetes can develop nerve problems at any time, but the longer a person has diabetes, the greater the risk. An estimated 50 percent of those with diabetes have some form of neuropathy, but not all with neuropathy have symptoms. The highest rates of neuropathy are among people who have had the disease for at least 25 years. Diabetic neuropathy also appears to be more common in people who have had problems controlling their blood glucose levels, in those with high levels of blood fat and blood pressure, in overweight people, and in people over the age of 40. The most common type is peripheral neuropathy, also called distal symmetric neuropathy, which affects the arms and legs. Top Causes The causes are probably different for different varieties of diabetic neuropathy. Researchers are studying the effect of glucose on nerves to find out exactly how prolonged exposure to high glucose causes neuropathy. Nerve damage is likely due to a combination of factors:

26. Diabetic Foot, The: Diagnosing And Managing Chronic Painful Diabetic Neuropathy Table 1. Classification of diabetic neuropathies* Diffuse neuropathies Distal symmetricsensorimotor polyneuropathy Autonomic neuropathy Symmetric proximal http://www.findarticles.com/cf_dls/m0MDQ/1_7/114708489/p3/article.jhtml?term=

27. Diabetic Neuropathy: The Nerve Damage Caused By Diabetes Several scientists feel this may be the missing link in the ultimatetreatment of diabetic neuropathies, but as of now no one is sure. http://www.footcare4u.com/aodf/neuropathy.html

What does a paper clip, a safety pin, a Lego block, a key, a hair pin, a rock, and a dime all have in common? They were all undetected foreign objects found in the shoes of people with diabetic neuropathy. What Is Diabetic Neuropathy? Diabetic neuropathy is a nerve disorder most commonly caused by the high levels of sugar in the blood. It represents the most common complication of diabetes. It is also the major contributor of the triad of diabetic neuropathy, Peripheral Vascular Disease and infection, which are the primary causes of all chronic foot diabetic ulceration that can lead to amputation. In fact in over 20 years in private practice I can not ever recall seeing a severe diabetic foot ulcer without diabetic neuropathy being present. As such they represent an ongoing health problem to the public of major importance. The most common form of diabetic neuropathy seen is known as "distal symmetrical polyneuropathy." In layman's terms this means the nerves affected are the far reaching nerves seen in the hands and feet, normally on both right and left sides

28. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor See Also Health Conditions and Diseases Endocrine Disorders Pancreas Diabetes.News about diabetic neuropathies More news about diabetic neuropathies . http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica

Match: sort by: relevance date Free Services Subscribe by email RSS newsfeeds PDA-friendly format loc="/images/" A A A Find Jobs In: Healthcare Engineering Accounting College Contract / Freelance Customer Service Diversity Engineering Executive Healthcare Hospitality Human Resources Information Tech International Manufacturing Nonprofit Retail All Jobs by Job Type All Jobs by Industry Relocating? Visit: Moving Resources Moving Companies Mortgage Information Mortgage Calculator Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Peripheral Nervous System Diabetic Neuropathies (4 links) See Also: Health: Conditions and Diseases: Endocrine Disorders: Pancreas: Diabetes News about Diabetic Neuropathies Innovative 'Self Healing' Bandage To Help Diabetics (May 26, 2004) full story Oxygen Therapy May Improve Vision Worsened By Diabetes (May 19, 2004) full story Mechanism Found That May Protect Kidneys In Early Stages Of Diabetes (May 14, 2004) full story 'Good Guy' Blood Cells Are Now Suspects In Heart Disease, Diabetes (May 13, 2004) full story Cinnamon May Help To Alleviate Diabetes (April 14, 2004)

29. Diabetic Neuropathy Medline NLM definition of diabetic neuropathies Peripheral, autonomic, andcranial nerve disorders that are associated with DIABETES MELLITUS. http://www.sciencedaily.com/encyclopedia/diabetic_neuropathy

Match: sort by: relevance date Free Services Subscribe by email RSS newsfeeds PDA-friendly format loc="/images/" A A A Find Jobs In: Healthcare Engineering Accounting College Contract / Freelance Customer Service Diversity Engineering Executive Healthcare Hospitality Human Resources Information Tech International Manufacturing Nonprofit Retail All Jobs by Job Type All Jobs by Industry Relocating? Visit: Moving Resources Moving Companies Mortgage Information Mortgage Calculator Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Outdoor Living Encyclopedia Main Page See live article Diabetic neuropathy Medline NLM definition of Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. Note: The original source of this article can be found on the main Wikipedia Web site.

30. Endotext.com - Diabetes, Diabetic Neuropathies diabetic neuropathies Chapter 35 Aaron Vinik, MD December 18, 2002, DIFFUSE NEUROPATHIES.Proximal motor neuropathies (Diabetic amyotrophy, femoral neuropathy). http://www.endotext.org/diabetes/diabetes28/diabetes28.htm

DIABETIC NEUROPATHIES Chapter 35 - Aaron Vinik, MD December 18, 2002 Contents Contributors Search Introduction Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care(1;2). It is the most common form of neuropathy in the developed countries of the world, accounts for more hospitalizations than all the other diabetic complications combined, and is responsible for 50-75% of non-traumatic amputations (2;3). DN is a set of clinical syndromes that affect distinct regions of the nervous system, singly or combined. It may be silent and go undetected, while exercising its ravages, or it may present with clinical symptoms and signs that although nonspecific and insidious with slow progression but also mimic those seen in many other diseases. It is, therefore, diagnosed by exclusion. Classification DN is not a single entity but a number of different syndromes, ranging from subclinical to clinical manifestations depending on the classes of nerve fibers involved. According to the San Antonio Convention (10), the main groups of neurologic disturbance in diabetes mellitus include: 1) subclinical neuropathy, determined by abnormalities in electrodiagnostic and quantitative sensory testing, 2) diffuse clinical neuropathy with distal symmetric sensorimotor and autonomic syndromes, and 3) focal syndromes.

31. Endotext.com - Diabetes, Diabetic Neuropathies http://www.endotext.org/diabetes/diabetes28/diabetesframe28.htm

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32. What Is Diabetic Neuropathy - Prevention, Causes, Symptoms, Types, Diagnoses, & Diabetic Neuropathy is a nerve disorder caused by Diabetes. Vinik, A., et al.,diabetic neuropathies, Diabetes Care, December 1992, pp. 19261975. http://www.diabetestoolbox.com/diabeticneuropathy.asp

HOME INFORMATION SHIPPING / PAYMENT INFO SHOPPING CART ... Baskets Please leave your E-Mail address below to receive future information and specials. ...Back To Diabetic information and articles Diabetic Neuropathy What Is Diabetic Neuropathy? How Common Is Diabetic Neuropathy? What Causes Diabetic Neuropathy? What Are the Symptoms of Diabetic Neuropathy? ... Additional Reading What Is Diabetic Neuropathy Diabetic neuropathy is a nerve disorder caused by diabetes. Symptoms of neuropathy include numbness and sometimes pain in the hands, feet, or legs. Nerve damage caused by diabetes can also lead to problems with internal organs such as the digestive tract, heart, and sexual organs, causing indigestion, diarrhea or constipation, dizziness, bladder infections, and impotence. In some cases, neuropathy can flare up suddenly, causing weakness and weight loss. Depression may follow. While some treatments are available, a great deal of research is still needed to understand how diabetes affects the nerves and to find more effective treatments for this complication. DCCT: Can Diabetic Neuropathy Be Prevented?

33. Diabetes Self-Management - Treating Neuropathy While Waiting For A Cure The best first line of treatment for all diabetic neuropathies, every medical professionalmakes a point to remind us, is still control of blood sugar levels. http://www.diabetesselfmanagement.com/article.cfm?sid=2&tid=41&aid=466&sk=5WY5

34. CDC's Diabetes Program - Publications & Products - The Prevention And Treatment This most common of the diabetic neuropathies is characterized by insidious onset,symmetrical distribution, and progressive course. Diabetic Neuropathy. http://www.cdc.gov/diabetes/pubs/complications/neuro.htm

National Center for Chronic Disease Prevention and Health Promotion Diabetes Public Health Resource Home About the Program Site Map Contact Us Contents Conferences Diabetes FAQs Diabetes Projects Links ... Statistics Public Inquiries Call toll-free 1-877-CDC-DIAB Publications and Products The Prevention and Treatment of Complications of Diabetes Mellitus: A Guide for Primary Care Practitioners Neuropathy Background Persons with diabetes who develop neuropathy may have no symptoms or may experience pain, sensory loss, weakness, and autonomic dysfunction. Neuropathy may result in significant morbidity and may contribute to other major complications, such as lower extremity amputation. There are three major types of diabetic neuropathy: Distal symmetrical polyneuropathy. Focal neuropathy. Autonomic neuropathy. Distal symmetrical polyneuropathy. This most common of the diabetic neuropathies is characterized by insidious onset, symmetrical distribution, and progressive course. Although its cause is unclear, distal symmetrical polyneuropathy is believed to result from abnormal neural metabolism, generalized neural ischemia, or both. The onset and course of illness cannot be predicted for an individual patient, but increasing age, male sex, increasing height, longer duration of diabetes, poorer glucose control, hypertension, alcohol consumption, and smoking may be independent risk factors.

35. Ingenta Article Summary Thioctic Acid For Patients With assessment. Keywords diabetic neuropathies; Antioxidants, general; Thiocticacid, general Document Type Review article ISSN 11756349 http://www.ingenta.com/isis/searching/ExpandTOC/ingenta?issue=pubinfobike://adis

36. UMHS Department Page Oxidative stress and programmed cell death in diabetic neuropathy. Annals of theNew York Academy of Science, 959368383, 2002. diabetic neuropathies, http://www.med.umich.edu/neuro/russell.htm

Neurology Home Page Neurology Faculty Neurology Home Page Neurology Faculty James Russell, M.D., Assistant Professor Phone: Fax: E-mail: +1 734-761-5564 at the VA +1 734-763-3776 at UMHS jruss@umich.edu Assistant Professor Department of Neurology MBchB : Godfrey Huggins School of Medicine, University of Zimbabwe Residency : Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA Fellowship (peripheral nerve/neuromuscular): Mayo Clinic and Foundation, Rochester, MN Fellowship (electrophysiology/neuromuscular): National Institute of Neurological Diseases and Stroke, National Institutes of Health (NIH) M.S. : Clinical Research Design and Statistical Analysis, University of Michigan, 2001 Reviewer for NIH Brain Disorders and Clinical Neurosciences (BDCN2) Study Section, 2002-present Study Section , American Diabetes Association - Diabetic Complications, 2002-2005 Clinical Activities: Neuromuscular Diseases Clinic UMHS Electrophysiology Laboratory UMHS and VAHS Research Interests: Basic Science Research: mechanisms of programmed cell death (PCD) in diabetic neuropathy, role of IGF-I and other neurotrophic factors in control of PCD pathways, role of IGF-I in neuronal and Schwann cell adhesion and mechanisms of myelination, role of mitochondrial neurotoxins in cell death.

37. Neurological Disorders, Peripheral Nervous System, Diabetic Neuropathies Submit Your Site to the diabetic neuropathies category. Sponsored DiabeticNeuropathies Sites. Submit Your Site to the diabetic neuropathies category. http://www.iseekhealth.com/diabetic_neuropathies-2110.php

Home About Us Contact Submit Your Site Search : Home Health Conditions and Diseases Neurological Disorders ... Diabetic Neuropathies More Diabetic Neuropathies Categories: Submit Your Site to the Diabetic Neuropathies category Sponsored Diabetic Neuropathies Sites Epilepsy Book Store At WellnessBooks.com Comprehensive source to books on Epilepsy. Includes community boards and chat, book reviews and online ordering. Neurological Disorders Due To An Imbalance? Do you have a neurological disorder? This may be due to an imbalance. Check the balance of your system and get natural recommendations for restoring balance. Diabetic Neuropathy - A description of this disorder from Medline National Library of Medicine. Dr. Vera Bril - Diabetic Research Studies - New research on the most common complication of diabetes. Two articles; Can it be Treated and Treatment with Aldose Reductase Inhibitors. Neuro-Patient Resource Centre - Details about diabetic neuropathies, including the types, who gets it, testing and what can be done. NINDS Diabetic Neuropathy Information Page - Diabetic neuropathy information sheet compiled by NINDS.

38. Strelitz Diabetes Institutes: The Research Institute, Publications Vinik, AI, Milicevic, Z. Recent advances in the diagnosis and treatment of diabeticneuropathy. Sima AAF, Thomas PF, Ishii D, Vinik A. diabetic neuropathies. http://www.evms.edu/diabetes/research-pubs-2.html

Department Information Clinical Care Institute Education Institute Research Institute ... Diabetes Institutes Foundation (off-site) Completed Publications in Journals 1996 - present Books and Chapters of Books Abstracts 1996 - present Text listing of all publications Research Publications - Completed Publications in Scientific Journals, 1996 - present 55. Rosenberg, L., Kahlenberg, M., Vinik, A.I., Duguid, W.I. Paracrine/autocrine regulation of pancreatic islet cell proliferation and differentiation in the hamster: studies using parabosis. Clin Invest Med., 1996; Vol 19:3-12. 56. Rosenberg, L., Vinik, AL, Pittenger, GL, Rafaeloff, R., Duguid, WP. Islet cell regeneration in the diabetic hamster panceas with restoration of normoglycemia can be induced by a local growth factor(s). Diabetologia 39: 256-262, 1996. 57. Rafaeloff, R., XF Qin, Barlow SW, Rosenberg L, Vinik, AL. Identification of differentially expressed genes induced in pancreatic islet neogenesis. FEBS Letters 378(3):219-223, 1996. 58. Rosenberg L, Rafaeloff R, Clas D, Kakugawa Y, Pittenger GL, Vinik AI, Duguid WP. Induction of Islet Cell Differentiation and New Islet Formation in the Hamster. Further Support for a Ductular Origin. Pancreas, Vol 13, No.1, pg. 38-46. 1996.

39. Strelitz Diabetes Institutes: The Research Institute, Publications 24. Vinik AK, Holland MT, Le Beau JM, Liuzzi FJ, Stansberry KB, Colen LBdiabetic neuropathies. Diabetes Care, Vol 1512, 19261975, 1992. 25. http://www.evms.edu/diabetes/research-pubs-1.html

Department Information Clinical Care Institute Education Institute Research Institute ... Diabetes Institutes Foundation (off-site) Completed Publications in Journals 1996 - present Books and Chapters of Books Abstracts 1996 - present Text listing of all publications Research Publications - Completed Publications in Scientific Journals, 1. Gonin JM, Kadrofske, MM, Schmaltz S, Bastyr EJ, Vinik AI: Corrected Q-T interval prolongation as diagnostic tool for assessment of cardiac autonomic neuropathy. Diabetes Care 13(1):68-71, 1990. 2. Abelson JL, Nesse RM, Vinik AI: Treatment of Panic-Like Attacks with a Long-Acting Analogue of Somatostatin. J Clin Psychopharmacol 10(2):128-132, 1990. 3. Bastyr EJ, Kadrofske MM, and Vinik AI: Platelet Activity and Phosphoinositide Turnover Increase with Advancing Age. Amer J of Med 88:601-606, 1990. 4. Vinik AI, Gonin J, England BG, McLeod MK, and Cho K: Substance P in neuroendocrine tumors and idiopathic flushing. The value of pentagastrin stimulation tests and the effects of somatostatin analogue. J Clin Endocrinol Metab, 70:1702-1709, June, 1990. 5. Vinik AI, Moattari AR, Cho K, and Thompson NW: Transhepatic portal vein catheterization for localization of sporadic and MEN gastrinomas: a 10 year experience. Surgery 107:246-255, 1990.

40. Life Extension Magazine October 1996 LE Magazine March 1996. Alpha Lipoic Acid Treatment Of diabetic neuropathiescontinued from For Diabetes, Atherosclerosis And Aging. http://www.lef.org/magazine/mag96/march96_update5.html

var WebSiteBaseURL = "http://www.lef.org/magazine/mag96/march96_update5.html" translation by SYSTRAN MEMBERSHIP PRODUCTS MAGAZINE ... CHECKOUT LE Magazine March 1996 Alpha Lipoic Acid Treatment Of Diabetic Neuropathies continued from For Diabetes, Atherosclerosis And Aging One of the most damaging complications of diabetes is nerve damage at various sites of the body, which inactivates and weakens muscles, can be extremely painful, and can cause blindness when the retina of the eye is attacked (diabetic retinopathy). Alpha lipoic acid has been shown to be highly effective in treating such neuropathies. The clinical benefits of alpha lipoic acid in diabetics was discovered by Beck and Schneeweiss in 1959. There have been a half dozen or so studies since then confirming these results. In a placebo controlled, double blind study, 20 diabetics were given intravenous infusions of 200 mg a day of alpha lipoic acid or placebo for 21 days. The results showed dramatic improvement in some clinical symptoms in some of the experimental subjects. For example, before being treated with alpha lipoic acid, four patients had severe pain and six patients had moderate pain. After treatment, five of the patients had no pain, four had moderate pain, and only one had severe pain. In a longer single blind study, alpha lipoic acid was compared to vitamin B1 as a treatment for diabetic neuropathy. In this study, 600 mg/day of alpha lipoic acid or 400 mg mg/day of vitamin B1 were administered intravenously and intramuscularly, respectively, to diabetics for 3 weeks, followed by 12 weeks of oral administration of the same doses.

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