101. Richard Collyers End To End Page A sponsored cycle ride, by three Norfolk police officers from Lands End to John o'Groats, in June 2000 to raise money for the cystic fibrosis Trust. http://www.collyer.clara.net/

102. Cystic Fibrosis Foundation ... Adding Tomorrows Every Day Works to assure the development of the means to cure and control cystic fibrosis and to improve the quality of life for those with the disease. Site includes local events, volunteer opportunities, contact information, and links to the national foundation. http://www.cff.org/alabama.htm

About the Cystic Fibrosis Foundation News Publications ... Special Event Prizes Alabama Chapter News and Information Volunteer Leadership Initiative 2003 View this Chapter's News and Information Upcoming Volunteer Opportunities Volunteer With so many events each year, the Alabama Chapter relies heavily on the time and talent of our dedicated volunteers in fund-raising efforts. Th... (more) Calendar Of Events view all past events This chapter has no upcoming events. Sponsors We need your help! The Cystic Fibrosis Foundation is always looking for sponsors! It is through the generosity of our sponsors and volunteers that we are able to wage our battle against cystic fibrosis. For each day we work, and for every dollor we raise, we are adding tomorrows every day for people with cystic fibrosis. Contact Information Alabama Chapter 3918 Montclair Road Suite 201 Mountain Brook, AL 35213 fax: (205) 879-9448 http://www.cff.org/alabama.htm alabama@cff.org

103. Department Of Paediatrics Cystic Fibrosis cystic fibrosis. Table of Contents. Introduction. cystic fibrosis occurs in about 1 in 2,500 births in Victoria. All patients are seen http://www.med.monash.edu.au/paediatrics/resources/cf.html

Monash M N H S Paediatrics Resources DEPARTMENT OF PAEDIATRICS Home About Us Programs Resources ... 5th Year Course Material Cystic Fibrosis Table of Contents Introduction Inpatient Management Children with Possible CF Treatment of Exacerbations of Chest Infection On Discharge Meconium Ileus Equivalent Introduction Cystic fibrosis occurs in about 1 in 2,500 births in Victoria. All patients are seen at the Royal Children's Hospital at the time of diagnosis, which is usually in the first year of life. Some patients living in the south-east of the city or eastern Victoria are cared for jointly by the department of Thoracic Medicine at the RCH and the Department of Paediatric Respiratory Medicine, MMC. The prognosis has improved very considerably over the last 20 years and most patients now reach adulthood. In the ward the resident medical staff will see patients who have acute flare-ups of chest infection and those with severe lung disease. The 50% of patients who have little chest trouble are rarely admitted to the ward, so staff are likely to have a biased view of the condition. The development of a very positive attitude by the parents from the time of diagnosis seems to be very important in the prognosis. The handling of the family at the time of diagnosis is carefully planned. If they are given a gloomy outlook, this can be hard to change.

104. Cystic Fibrosis International Medical A-Z Directory Biomedical directory with listings of hospitals, charities, research, and information by topic and location. http://www.cellscience.com/CFmain.html

Cystic Fibrosis rating for web sites is intended to serve only as an indication of the design quality, clarity, presentation and style of the URL, and is in no way intended as a judgement of the quality of services or information provided. To have a site listed is itself an indication that the site is of general interest - (Guide: NR Not rated, strong, good, excellent) Date page was last modified

105. Advances In Cystic Fibrosis Advances in cystic fibrosis. cystic fibrosis is caused by many different mutations of the CF gene; to date, more than 600 unique mutations have been described. http://www.childsdoc.org/fall97/cf/cf.asp

Home Features Index Features Departments Information ... Steven Boas, MD Attending Physician Division of Pulmonary and Critical Care Medicine Medical Director, Pumonary Function Testing/Exercise Laboratory Children's Memorial Hospital Assistant Professor of Pediatrics Northwestern University Medical School Susanna McColley, MD Attending Physician Division of Pulmonary and Critical Care Medicine Children's Memorial Hospital Assistant Professor of Pediatrics Northwestern University Medical School The Cystic Fibrosis Foundation's home page is a great jumping off point for many topics related to CF. For readers interested in more information on the CF's genetic mutations, see the Cystic Fibrosis Mutation Data Base , which is a site belonging to the Department of Genetics, The Hospital for Sick Children in Toronto, Ontario, Canada. Contact us Advances in Cystic Fibrosis STEVEN R. BOAS, MD SUSANNA A. MCCOLLEY, MD THE DISCOVERY OF the gene responsible for cystic fibrosis (CF) in 1989 has led to an explosion of scientific information related to the disease and has transformed our understanding of it. For the first time, investigators are focusing on the development of treatments based on the underlying cellular defect. In this article, we review advances in genetics and molecular biology, as well as in clinical care, during the past decade. We also discuss the significance of the inflammatory response in CF lung disease and new and experimental CF therapies. The molecular basis of CF In 1989, investigators discovered the CF gene using novel approaches. The gene product, called the cystic fibrosis transmembrane conductance regulator (CFTR), is a membrane-based protein with an active transport function. This is consistent with previous findings that the primary defect in CF cells is faulty transport of ions, especially of chloride. Conclusive information regarding the role of CFTR in the basic CF defect came with the demonstration that defective cAMP-dependent chloride conductance in CF cells was restored when CFTR cDNA was transfected and expressed in those cells.

106. Proteome Systems - Proteomics Technology And Discovery - Home Specializes in the development of new technology for proteomics and its application to discovery programs in the areas of cystic fibrosis, cancer, infectious disease and aging. US and Japanese offices with headquarters in Sydney, Australia. http://www.proteomesystems.com/

Home Contact Us var hcenter=(((window.screen.availWidth-640)/2)-23); var vcenter=(window.screen.availHeight-490)/2; Log On Online Catalogue Search: Advanced Search var baseHREF = "http://www.proteomesystems.com/inc/106/Menu/"; CORPORATE  TECHNOLOGY DISCOVERY DIAGNOSTICS ... INVESTORS Special Feature Proteome Systems and HighQ collaborate to identify and characterise biomarkers for monitoring disease progression and treatment of Huntington’s disease. 19 April 2004 - Proteome Systems and the High Q Foundation today announced an agreement to collaborate on a proteomic program for Huntington’s Disease (HD), comprising biomarker identification and molecular characterization of the Huntingtin protein. Proteome Systems will characterize changes in protein expression and modification that result from malfunction of the Huntingtin protein in order to identify biomarkers of HD. more > Multifunctional electrophoresis systems The IsoelectrIQ ™ and ElectrophoretIQ ™ revolutionise the purification of proteins for proteomics. Each unit is highly integrated, with unique 2-in-1 and 3-in-1 functionality, bringing you an advanced and comprehensive solution for two-dimensional gel electrophoresis... more » Discovery Programs Proteome Systems currently has Discovery projects in the areas of Respiratory disease, Cancer, Infectious disease and Ageing and age-associated disease...

107. Cystic Fibrosis cystic fibrosis. cystic fibrosis (CF) is one of the most common autosomal recessive diseases in the Caucasian population, occurring http://www.phd.msu.edu/DNA/cf_fact.html

B240 Life Science Building, East Lansing, MI 48824-1317, Fax: 517-353-8464 Email: dnadiag@msu.edu TESTS OFFERED TEST INFORMATION FOR: Cystic Fibrosis Hereditary Hemochromatosis Apolipoprotein E Genotyping Fragile X Syndrome Methylenetetrahydrofolate reductase Cystic Fibrosis Cystic fibrosis (CF) is one of the most common autosomal recessive diseases in the Caucasian population, occurring in 1 out of every 2,500 - 3,300 newborns. CF can occur in other ethnic groups, but is most common in Caucasians. CF results from mutations in the CFTR gene, which is important for maintaining chloride balance in the cell. Carrier Risks Vary by Ethnic Group: Ethnic Group Carrier Rate Caucasian (non-Hispanic/non-Ashkenazi Jewish) 1 in 25 Ashkenazi Jewish 1 in 25 Hispanic 1 in 46 African American 1 in 65 Asian 1 in 90 Reasons for CF Testing: Confirmation of diagnosis in affected individuals Carrier identification in persons with a family history Carrier identification in persons currently pregnant or considering pregnancy Screening of sperm and egg donors Abnormal fetal ultrasound (i.e. echogenic bowel)

108. Cystic Fibrosis Message Board Topics. cystic fibrosis Message Board. BOARDS; FRIEND WITH cystic fibrosis Alexis 210604 12/22/00 (0) DOES ANYONE HAVE ANY NEW .. http://www.healthboards.com/cystic-fibrosis/

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109. Cystic Fibrosis - Lungs: Pulmonary And Respiratory Health And Medical Informatio cystic fibrosis. cystic fibrosis At A Glance. cystic fibrosis (CF) is one of the most common serious genetic (inherited) diseases. http://www.medicinenet.com/Cystic_Fibrosis/article.htm

MedicineNet Home Lungs Home > Cystic Fibrosis Advanced Search Printer-Friendly Format Add to Favorites Email to a Friend ... Next page Cystic Fibrosis Alternative names for the disease: Cystic fibrosis (CF) Cystic fibrosis of the pancreas Mucoviscidosis Cystic fibrosis transmembrane conductance regulator (CFTR) Respiratory problems: Chronic infections of the lungs Emphysema Progressive respiratory insufficiency Gastrointestinal problems (including pancreas and liver): Pancreatic insufficiency (with no secretion of trypsin and other digestive enzymes into the intestine) Intestinal obstruction at birth (due to this lack of digestive enzymes) Continuing deficiency of pancreatic enzymes Biliary tract obstruction (blockage of the bile system) Constriction of the common bile duct Cirrhosis of the liver (of the type called biliary cirrhosis) Recurrent episodes of pain in the right lower part of the abdomen (mimicking appendicitis) Adenocarcinoma of the ileum, a part of the small intestine (a rare problem) Heart problem: Cor pulmonale (progressive overwork and failure of the right side of the heart from the task of pumping blood through the diseased lungs) Reproductive problem: Infertility of males Laboratory findings: Positive sweat test for CF (due to salty sweat) Lack of trypsin in the stool (and high level of trypsin in blood serum) DNA testing for CF (demonstrates the presence of the common delta-F508 codon deletion or one of the other variant CF mutations) Inheritance:

110. New Scientist Curry spice could alleviate cystic fibrosis. 1900 22 April 04. A spice used in curry could help alleviate cystic fibrosis, new research suggests. http://www.newscientist.com/news/news.jsp?id=ns99994912

111. The Ortho-McNeil CF Care Website Provides people with cystic fibrosis, family members, and the CF community with quick and easy access to education and information. http://www.cfcare.com

112. THE MERCK MANUAL, Sec. 19, Ch. 267, Cystic Fibrosis Chapter 267. cystic fibrosis. Topics. General. It encodes a membraneassociated protein called the cystic fibrosis transmembrane regulator (CFTR). http://www.merck.com/mrkshared/mmanual/section19/chapter267/267a.jsp

113. University Of Colorado Health Sciences Center - Duncan Lab Current projects, protocols and facilities combining mass spectrometry, 2D gels and databases, for mapping disease states such as cystic fibrosis, cancer and allergy. Includes terms of use, user login, and meetings in Denver. http://proteomics.uchsc.edu/

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114. THE MERCK MANUALSECOND HOME EDITION, Ch. 53, Cystic Fibrosis Section 4. Lung and Airway Disorders. Chapter 53. cystic fibrosis. Topic cystic fibrosis. cystic fibrosis. cystic fibrosis http://www.merck.com/mrkshared/mmanual_home2/sec04/ch053/ch053a.jsp

115. Cyber Campus A computer course aiming to empower and educate people with cystic fibrosis. From the cystic fibrosis Association of Ireland (CFAI). http://www.internet-ireland.ie/horizon/

116. Cystic Fibrosis - Wikipedia, The Free Encyclopedia cystic fibrosis. cystic fibrosis also causes a defect in the vas deferens causing sterility in approximately 98% of males with the disease. http://en.wikipedia.org/wiki/Cystic_fibrosis

Cystic fibrosis From Wikipedia, the free encyclopedia. Cystic fibrosis (abbreviated CF), also called mucoviscidosis , is an autosomal recessive hereditary disease that affects the lungs, sweat glands and the digestive system. The disease can be diagnosed by a high salt concentration in a baby's sweat. The symptoms usually develop during early childhood. Both lungs and pancreas produce abnormally viscous mucus . The mucus in the lungs can become a growth medium for bacteria, resulting in chronic respiratory infections and eventual permanent damage to the lung tissue. As lung function deteriorates, CF patients develop pulmonary hypertension and eventually cor pulmonale . Death usually occurs from severe infection or heart failure. In addition to frequent pulmonary infections, most persons with CF also have problems with digestion , particularly the digestion of fats. This leads to malabsorption and difficulty gaining and maintaining weight, which in turn affects overall health. This is due to the abnormally sticky mucus that blocks the release of digestive enzymes from the pancreas . Pancreatic insufficiency is treated with supplemental enzymes. Usually water-miscible forms of the fat-soluble vitamins A, D, E, and K are required as the decreased fat absorption can lead to deficiencies of these vitamins.

117. We'll Find A Cure // This Time Around Supports fans with cystic fibrosis. Lyrics, fun, links and campaigns. http://www.fallenstars.com/hmh/

Java Applet list of Hanson fans with cystic fibrosis Please take a moment to let it load. No applet? Click here Best viewed with Microsoft Internet Explorer. To my cousin Rae-Anne, my best friend Felicity and everyone touched by CF, this page is for you. FastCounter by LinkExchange HTP Magazine. House Of Hope Central i'll admit it ... i love hanson.

118. BUBL LINK / 5:15 Internet Resources: Cystic Fibrosis system, hepatitis DeweyClass 616.3 ResourceType index Location uk Last checked 19990508 CFWeb Online Information about cystic fibrosis Answers to http://bubl.ac.uk/link/c/cysticfibrosis.htm

BUBL LINK / 5:15 Catalogue of Internet Resources Home Search Subject Menus A-Z ... About Cystic fibrosis A-Z Index Titles Descriptions OMNI Subject Listing for Digestive System CF-Web: Online Information about Cystic Fibrosis Cystic Fibrosis Foundation Cystic Fibrosis Trust ... LungNet Page last updated: 17 March 2003 Comments: bubl@bubl.ac.uk OMNI Subject Listing for Digestive System Set of links to selected, evaluated and annotated Internet resources relevant to the digestive system, including gastroenterology, hepatology, hernias, ulcers and diseases of the liver and pancreas. Author: OMNI, Nottingham University Subjects: cystic fibrosis, digestive system, hepatitis DeweyClass: ResourceType: index Location: uk Last checked: CF-Web: Online Information about Cystic Fibrosis Answers to frequently asked questions about cystic fibrosis, for doctors, researchers and non-technical readers. Author: Robert Calhoun and Michael Ernst Subjects: cystic fibrosis DeweyClass: ResourceType: document Location: usa Last checked: Cystic Fibrosis Foundation The mission of the Cystic Fibrosis Foundation is to assure the development of the means to cure and control cystic fibrosis and to improve the quality of life for those with the disease. Author: Cystic Fibrosis Foundation Subjects: cystic fibrosis, health charities

119. CF Advantage The mutation that causes deadly cystic fibrosis has survived for 52,000 years perhaps because it offers protection against diarrhea. By Josie Clausiusz http://wsrv.clas.virginia.edu/~rjh9u/cysfib.html

Hidden Benefits Josie Clausiusz The mutation that causes deadly cystic fibrosis has survived for 52,000 years - perhaps because it offers protection against diarrhea. When humans left the Near East and invaded Europe around 40,000 years ago, they took with them bone and stone tools for hunting and engraving, early art in the form of beads and pendants, and social skills that were probably superior to those of Europe's resident Neanderthals. It now seems they also took with them a mutant gene: the gene for the deadly disease cystic fibrosis. So robust is this gene that it spread all over Europe; cystic fibrosis is now the most common fatal genetic disorder among Caucasians. How could the disease have been passed from generation to generation for so long, when until the advent of modern medicine it generally killed people before they could have children? Recent experiments on mice offer an answer. They suggest that the 5 percent of all Caucasians who carry just one copy of the cystic fibrosis gene - and thus don't suffer from the disease - are protected against another deadly scourge: diarrhea. The gene for cystic fibrosis was discovered in 1989. It codes for a protein that forms channels in cell membranes, especially the cells lining the intestines and airways. Normally these channels funnel chloride ions out of a cell, thus making its surroundings saltier; that in turn draws water out of the cell by osmosis. In the lungs this fluid washes away bacteria and other unwanted debris. In the intestines it does the same and also brings digestive enzymes into contact with food. In sweat glands chloride channels have an additional function; they recycle salt out of the glands and back into the skin before it can be lost to the outside world.

120. Cystic Fibrosis Disease Profile Genetic Disease Profile cystic fibrosis. For more about the gene that causes cystic fibrosis, see the CFTR Gene Profile. Other cystic fibrosis Resources. http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/cf.shtml

Human Genome Project Information Genomics:GTL Microbial Genome Program home The U.S. Department of Energy Biological and Environmental Research program funds this site. Genetic Disease Profile: Cystic Fibrosis For more about the gene that causes cystic fibrosis, see the CFTR Gene Profile . The following was taken from NIH Publication No. 95-3650 Cystic Fibrosis Timeline Middle Ages - In medieval folklore, infants with salty skin, a symptom of cystic fibrosis, are considered "bewitched" because they routinely die an early death. - Fanconi refers to the previously nameless condition as "cystic fibrosis with bronchiectasis." - Andersen of Columbia University develops the first comprehensive description of cystic fibrosis symptoms. - Lowe establishes that cystic fibrosis is a recessive genetic disorder. - After observing excessive dehydration of cystic fibrosis patients during a New York City heat wave, di Sant' Agnese of Columbia University formally reports to the American Pediatric Society that CF patients secrete excessive amounts of salt in their sweat. This observation leads to development of the sweat test as a diagnostic standard for cystic fibrosis.

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