21. HealthCentral - General Encyclopedia - Crigler-Najjar Syndrome General Health Encyclopedia, criglernajjar syndrome. Causes, incidence, and risk factors crigler-najjar syndrome is inherited as an autosomal recessive trait. http://www.healthcentral.com/mhc/top/001127.cfm

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22. Disease Directory : Genetic Disorders : Crigler-Najjar Syndrome Diseases Genetic Disorders criglernajjar syndrome. AllRefer Health - crigler-najjar syndrome Symptoms Signs (Arias crigler-najjar syndrome. http://www.diseasedirectory.net/Genetic_Disorders/Crigler-Najjar_Syndrome/defaul

Wednesday, June 02, 2004 Genetic Disorders Aarskog Syndrome Aase Syndrome Ablepharon-Macrostomia Syndrome ... Genetic Disorders : Crigler-Najjar Syndrome Austin Health Information - An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Conditions and Diseases - Crigler-Najjar Syndrome Top Links - Crigler-Najjar Syndrome Web Site Links. HealthCentral - General Encyclopedia - A look at crigler-najjar syndrome including, the symptoms Crigler Najjar Syndrome Type I,Bilirubin Glucuronosyltransferase ... - Crigler Najjar Syndrome Type I,Bilirubin Glucuronosyltransferase Deficiency Type I,Uridine Diphosphate Glucuronosyltransferase Severe Def. Crigler-Najjar Disease - Bi-lingual site with information and links on this disease. Crigler-Najjar syndrome - Crigler-Najjar syndrome. Glucuronyl transferase deficiency (type I); Arias syndrome (type II Crigler-Najjar). Causes, incidence, and risk factors: CRIGLER-NAJJAR SYNDROME - CRIGLER-NAJJAR SYNDROME - A rare genetic defect (autosomal recessive) where there is the inability to form bilirubin glucuronide due to the absence of the Crigler-Najjar Syndrome - Crigler-Najjar Syndrome Directory: Guide to Crigler-Najjar Syndrome sites on the internet. Crigler-Najjar Syndrome.

23. Disease Directory : NEJM -- Treatment Of The Crigler-Najjar Syndrome Type I With Diseases Genetic Disorders criglernajjar syndrome NEJM Treatment of the crigler-najjar syndrome Type I with Directory Listing. http://www.diseasedirectory.net/detailed/25426.aspx

Wednesday, June 02, 2004 Genetic Disorders Aarskog Syndrome Aase Syndrome Ablepharon-Macrostomia Syndrome ... Crigler-Najjar Syndrome : NEJM Treatment of the Crigler-Najjar Syndrome Type I with ... Directory Listing Title: NEJM Treatment of the Crigler-Najjar Syndrome Type I with ... Description: PreviousPrevious, Volume 338:1422-1427, May 14, 1998, Number 20. Next Next. Treatment of the Crigler–Najjar Syndrome Type I with Hepatocyte Transplantation. Date Added: 2/16/2004 5:22:40 PM URL: http://content.nejm.org/cgi/content/short/338/20/1422

24. ORPHANET® Crigler-Najjar Syndrome ORPHANET. Orphanet database access. criglernajjar syndrome. Direct access to data Summary crigler-najjar syndrome is a very rare disease http://www.orpha.net/static/GB/criglernajjarsyndrome.html

25. Crigler-Najjar, Syndrome : Sites Et Documents Francophones Translate this page Crigler-Najjar, syndrome. Menu général CISMeF. Arborescence(s) du thesaurus MeSH contenant le mot-clé Crigler-Najjar, syndrome crigler-najjar syndrome http://www.chu-rouen.fr/ssf/pathol/criglernajjarsyndrome.html

Crigler-Najjar, syndrome Menu général CISMeF Définition [MeSH Scope Note ; traduction CISMeF] : Forme familiale d'hyperbilirubinémie congénital transmise autosomale récessive. Elle est caractérisée par un ictères et des lésions cérébrales provoquées par une insuffisance en glucuronyl transférase dans le foie et la conjugaison défectueuse de la bilirubine. Synonyme(s) MeSH Crigler-Najjar, maladie ; Ictère familial congénital Crigler-Najjar Arborescence(s) Crigler-Najjar, syndrome Crigler-Najjar syndrome maladies et malformations congénitales, héréditaires et néonatales métabolisme et nutrition, maladies Position du mot-clé dans l' (les) arborescence(s) : Vous pouvez consulter toutes les ressources ou seulement les principales ou utiliser l' outil de recherche les recommandations les documents concernant l' enseignement les documents destinés aux patients Ou consulter ci-dessous une sélection des principales ressources : Qualificatifs : diagnostic guide ressources Crigler-Najjar, syndrome de [Par Pr Labrune P. Site éditeur Orphanet base de données sur les maladies rares et les médicaments orphelins. Direction Générale de la Santé / INSERM ;

26. Health Library - criglernajjar syndrome type I is inherited as an http//www.PICKonline.org Crigler-Najjar Association 3134 mauckc@msn.com Internet www.criglernajjar.com. http://yalenewhavenhealth.org/library/healthguide/IllnessConditions/topic.asp?hw

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Home About Us Contact Submit Your Site Search : Home Health Conditions and Diseases Genetic Disorders ... Crigler-Najjar Syndrome More Crigler-Najjar Syndrome Categories: Submit Your Site to the Crigler-Najjar Syndrome category Sponsored Crigler-Najjar Syndrome Sites Cystic Fibrosis Book Store At WellnessBooks.com Comprehensive source to books on Cystic Fibrosis. Includes community boards and chat, book reviews and online ordering. Buy Genetic Disorders Products We link to merchants which offer Genetic Disorders products for sale. Online Doctors - Ask Us Now! Kasamba's variety of health experts- including Doctors, Specialists, Herbalists, Nurses and more- offer real help for affordable consultation fees- live via chat or e-mail! Buy Genetics Books At Amazon.com and Save! Would you like to save on Genetics Books at Amazon and other stores? Compare prices at BookSellersNow.com! Our site continually proves that online shopping can be fun! Austin Health Information - An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease - Bi-lingual site with information and links on this disease.

28. Genetic Disorders, Crigler-Najjar Syndrome Category Home Health Conditions and Diseases Genetic Disorders criglernajjar syndrome. * Site Title · The name of the site. http://www.iseekhealth.com/directory/index.php?method=show_link_exchange&directo

29. Health, Conditions And Diseases, Genetic Disorders: Crigler-Najjar Syndrome Disorders. Austin Health Information An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler http://www.combose.com/Health/Conditions_and_Diseases/Genetic_Disorders/Crigler-

Top Health Conditions and Diseases Genetic Disorders ... Crigler-Najjar Syndrome Related links of interest: Health:Conditions and Diseases:Nutrition and Metabolism Disorders Austin Health Information - An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease - Bi-lingual site with information and links on this disease. Davidson College Biology Department - A brief description of crigler-najjar syndrome along with some links for further study. NORD: Crigler Najjar Syndrome Type I - General information and further resources. Pediatric Database - A look at crigler-najjar syndrome, a definition, epidemiology, pathogenesis, clinical features, investigation and management. An inherited disorder of bilirubin metabolism in which bilirubin cannot be changed into its water-soluble form, bilirubin glucuronide. This is caused by an enzyme imbalance in the liver. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor The combose.com directory is based on the Open Directory and has been modified and enhanced using our own technology.

30. Disease - Crigler-Najjar Syndrome - Hartford, Connecticut , Saint Francis Care Disease crigler-najjar syndrome. Prevention Genetic counseling is recommended for prospective parents with a family history of crigler-najjar syndrome. http://www.saintfranciscare.com/11767.cfm

@import url(main.css); About Us Health Information Adam Article Manager CareMail Signup ... Ways To Help Adam Article Manager Back Back to main Health Information page Disease - Crigler-Najjar syndrome Liver anatomy Definition: Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ malfunctions. Alternative Names: Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar) Causes And Risk: Crigler-Najjar syndrome is caused by an abnormal gene which fails to produce a functional enzyme (bilirubin glucuronyltransferase) capable of converting bilirubin into a water-soluble and therefore, easily excreted form. As a result, bilirubin can build up in the body, which can damage the brain and other organs. The syndrome is inherited as an autosomal recessive trait. This means that the child must get the defective gene from both parents to develop the severe form of the condition. Parents who are carriers (with just one defective gene) have about half the normal enzyme activity of a normal adult. Infants who inherit the trait from both parents (this is called homozygous for the abnormal gene) develop severe jaundice (hyperbilirubinemia) beginning a few days after birth. If these infants are not treated, they may develop

31. Crigler-Najjar Syndrome criglernajjar syndrome. Definition Alternative Names Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar). http://www.drkoop.com/ency/article/001127.htm

Advertisement Search Dr. Koop Web MEDLINE Special Offers TV Specials Top Features Schizophrenia Hair Loss Liver Disease Allergies ... Impotence Resources Subscribe to our Free Newsletter Health Encyclopedia ... Privacy Policy Advertisement Advertisement Disease Injury Nutrition Poison ... Prevention Crigler-Najjar syndrome Definition: Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ malfunctions. Alternative Names: Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar) Causes, incidence, and risk factors: Crigler-Najjar syndrome is caused by an abnormal gene which fails to produce a functional enzyme (bilirubin glucuronyltransferase) capable of converting bilirubin into a water-soluble and therefore, easily excreted form. As a result, bilirubin can build up in the body, which can damage the brain and other organs. The syndrome is inherited as an autosomal recessive trait. This means that the child must get the defective gene from both parents to develop the severe form of the condition. Parents who are carriers (with just one defective gene) have about half the normal enzyme activity of a normal adult.

32. Crigler-Najjar Syndrome criglernajjar syndrome. Liver biopsy, enzyme assay for low-absent Glucuronyl transferase activity; A family history of crigler-najjar syndrome. http://www.drkoop.com/ency/article/001127sym.htm

Advertisement Search Dr. Koop Web MEDLINE Special Offers TV Specials Top Features Schizophrenia Hair Loss Liver Disease Allergies ... Impotence Resources Subscribe to our Free Newsletter Health Encyclopedia ... Privacy Policy Advertisement Advertisement Disease Injury Nutrition Poison ... Prevention Crigler-Najjar syndrome Alternative Names: Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar) Symptoms: A family history of Crigler-Najjar syndrome Yellow skin (jaundice) and eyes (icterus) that begins on the 2nd or 3rd day of life and progressively worsens Jaundice that persists beyond 2 weeks of life without an obvious cause Confusion and changes in thinking (resulting from brain toxicity of bilirubin) Signs and tests: Tests used to evaluate the liver function include: Unconjugated bilirubin in blood (would be highly elevated) Total bilirubin level (would be high) Conjugated bilirubin (would be low to absent) Liver biopsy enzyme assay for low-absent Glucuronyl transferase activity A family history of Crigler-Najjar syndrome Review Date: 11/8/2002 Reviewed By: David G. Brooks, M.D., Ph.D., Division of Medical Genetics, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

33. Crigler-Najjar Syndrome - General Practice Notebook criglernajjar syndrome. crigler-najjar syndrome is a rare form of congenital non-haemolytic hyperbilirubinaemia. Type I Crigler-Najjar http://www.gpnotebook.co.uk/cache/349175813.htm

Crigler-Najjar syndrome Crigler-Najjar syndrome is a rare form of congenital non-haemolytic hyperbilirubinaemia. Type I Crigler-Najjar syndrome is characterised by a total deficiency of hepatic glucuronyl transferase. It is inherited as an autosomal recessive. Conjugated bilirubin is absent from the serum. The majority die with kernicterus in the first year of life. Phototherapy can reduce the serum bilirubin by 50% and may be performed at home. Type II Crigler-Najjar syndrome is characterised by a partial deficiency of glucuronyl transferase. It is inherited as an autosomal dominant. Patients given phenobarbital often survive into adult life. Phototherapy may be used to lower the serum bilirubin level. Click here for more information...

34. Crigler-Najjar Syndrome - General Practice Notebook criglernajjar syndrome. Medical search. crigler-najjar syndrome is a rare form of congenital non-haemolytic hyperbilirubinaemia. http://www.gpnotebook.co.uk/medwebpage.cfm?ID=349175813

35. Conditions And Diseases - Crigler-Najjar Syndrome Top Links criglernajjar syndrome Web Site Links. Austin Health Information - An overview of crigler-najjar syndrome including symptoms, treatment and prevention. http://www.disease-resources.com/Top_Health_Conditions_and_Diseases_Genetic_Diso

Sub Categories Related Healthcare Subjects Disabilities Environmental Health Fitness Health Insurance ... Men's Health Crigler-Najjar Syndrome Web Site Links HealthCentral - General Encyclopedia A look at crigler-najjar syndrome including, the symptoms, treatment, diagnosis, prognosis and prevention. Pediatric Database A look at crigler-najjar syndrome, a definition, epidemiology, pathogenesis, clinical features, investigation and management. Davidson College Biology Department A brief description of crigler-najjar syndrome along with some links for further study. Austin Health Information An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease Bi-lingual site with information and links on this disease. NORD General information about crigler najjar syndrome type I, followed by further resources. Other Useful Health Web Links National Institutes of Health (NIH) US Government department in charge of medical research. AHRQ: Clinical Information Clinical information on evidence-based practice, clinical guidelines, medical effectiveness, pharmaceutical therapy, new technology, screening and preventive services, outcomes research, and the National Guideline Clearinghouse. The UK Health Technology Assessment Programme Site contains details of program's many projects and publications; an NHS national research and development initiative.

36. Crigler-Najjar Syndrome- Medcohealth.com criglernajjar syndrome. Source ADAM, Inc. Genetic counseling is recommended for prospective parents with a family history of crigler-najjar syndrome. http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?topicID=HE:Dise

37. RU News: First International Conference Treatment Of Crigler-Najjar Syndrome What Treatment of criglernajjar syndrome First international conference on rare, fatal liver disease that affects Amish, Mennonites and others. http://www.rockefeller.edu/pubinfo/liver.nr.html

Media Alert Issued: May 23, 1996 News from The Rockefeller University 1230 York Avenue, New York, NY 10021-6399 Contact: Marion E. Glick (212) 327-7900 (Journalists) (212) 327-8967 (Main) (212) 327-7876 (FAX) e-mail: glickm@rockvax.rockefeller.edu What: Treatment of Crigler-Najjar Syndrome: First international conference on rare, fatal liver disease that affects Amish, Mennonites and others. Who: Experts from around the world When: Monday, May 27, 8 a.m. to 5:45 p.m., and Tuesday, May 28, 8 a.m. to noon Where: Weiss Building, Room 305, at The Rockefeller University 1230 York Ave., New York City Crigler-Najjar Syndrome is a nearly always fatal genetic disorder that afflicts newborns. The disease is a deficiency in an enzyme that people need to control the production of bilirubin. When too much bilirubin accumulates, jaundice and severe brain damage occurs. Bilirubin is produced during the breakdown of hemoglobin, the blood's oxygen-carrying red pigment. Currently the disease is treated with phototherapy, to breakdown the bilirubin, followed by liver transplantation. However, liver transplantations may take place after permanent brain damage occurs. Investigators at The Rockefeller University have developed tin-mesoporphyrin, a drug that inhibits hemoglobin from breaking down. Currently, scientists are testing the drug in clinical trials. While the disease occurs worldwide, populations such as the Amish and Mennonites in which family and genetic histories can be established, afford an excellent opportunity for scientists and health care professionals to learn more about Crigler-Najjar Syndrome. Expected as attendees are a 31-year-old woman who is the oldest known living patient with Crigler-Najjar Syndrome, five Mennonite children with the disorder and their families as well as parents of patients from the United States, Canada, England, Germany and India.

38. Genetic Disorders: Crigler-Najjar Syndrome Genetic Disorders criglernajjar syndrome. An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease. http://www.puredirectory.com/Health/Conditions-and-Diseases/Genetic-Disorders/Cr

Genetic Disorders: Crigler-Najjar Syndrome Home Health Conditions and Diseases Genetic Disorders : Crigler-Najjar Syndrome google_ad_client = 'pub-3272565765518472';google_ad_width = 336;google_ad_height = 280;google_ad_format = '336x280_as';google_color_border = 'FFFFFF';google_color_bg = 'FFFFFF';google_ad_channel ='7485447737';google_alternate_color = 'FFFFFF';google_color_link = '0000FF';google_color_url = '008000';google_color_text = '000000'; Standard Listings Austin Health Information An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease Bi-lingual site with information and links on this disease. Pediatric Database A look at crigler-najjar syndrome, a definition, epidemiology, pathogenesis, clinical features, investigation and management. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor PureDirectory.com uses a modified version of the Open Directory.

39. :: Ez2Find :: Crigler-Najjar Syndrome com/criglernajjar; Davidson College Biology Department Site Info - Translate - Open New Window A brief description of crigler-najjar syndrome along with http://ez2find.com/cgi-bin/directory/meta/search.pl/Health/Conditions_and_Diseas

Guide : Crigler-Najjar Syndrome Global Metasearch Any Language English Afrikaans Arabic Bahasa Melayu Belarusian Bulgarian Catala Chinese Simplified Chinese Traditional Cymraeg Czech Dansk Deutsch Eesti Espanol Euskara Faroese Francais Frysk Galego Greek Hebrew Hrvatski Indonesia Islenska Italiano Japanese Korean Latvian Lietuviu Lingua Latina Magyar Netherlands Norsk Polska Portugues Romana Russian Shqip Slovensko Slovensky Srpski Suomi Svenska Thai Turkce Ukrainian Vietnamese Mode All Words Any Word Phrase Results Timeout Depth Adult Filter Add to Favorites Other Search Web News Newsgroups Images Guides Crigler-Najjar Syndrome ez2Find Home Directory Health Conditions and Diseases ... Genetic Disorders : Crigler-Najjar Syndrome Related Categories Health: Conditions and Diseases: Nutrition and Metabolism Disorders Web Sites Austin Health Information [Site Info] [Translate] [Open New Window] An overview of crigler-najjar syndrome including symptoms, treatment and prevention. URL: http://www.austin360.com/shared/health/adam/ency/article/001127.html Crigler-Najjar Disease [Site Info] [Translate] [Open New Window] Bi-lingual site with information and links on this disease. URL: http://it.geocities.com/criglernajjar

40. Crigler-Najjar Syndrome The New Health Directory, Directory, Home Health Conditions and Diseases Genetic Disorders criglernajjar syndrome (5) See Also http://www.thenewhealthfind.com/Health/ConditionsandDiseases/GeneticDisorders/Cr

Directory Home Health Conditions and Diseases Genetic Disorders : Crigler-Najjar Syndrome (5) See Also: Health: Conditions and Diseases: Nutrition and Metabolism Disorders Pediatric Database - A look at crigler-najjar syndrome, a definition, epidemiology, pathogenesis, clinical features, investigation and management. Davidson College Biology Department - A brief description of crigler-najjar syndrome along with some links for further study. Austin Health Information - An overview of crigler-najjar syndrome including symptoms, treatment and prevention. Crigler-Najjar Disease - Bi-lingual site with information and links on this disease. NORD - General information about crigler najjar syndrome type I, followed by further resources. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor Quick Links protein power PSORIASIS Insomnia Remedies cancer types ... home otoscope The New Health Directory Site Map Privacy Contact Advertise ... Health Directory

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