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  1. Corticobasal Degeneration and Related Disorders
  2. The Official Patient's Sourcebook on Corticobasal Degeneration: A Revised and Updated Directory for the Internet Age
  3. Corticobasal Ganglionic Degeneration: Cognitive And Functional Aspects
  4. Cognitive Disorders: Dementia, Delirium, Corticobasal Degeneration, Dementia With Lewy Bodies, Prevention of Dementia, Binswanger's Disease
  5. Distinct patterns of olfactory impairment in Alzheimer's disease, semantic dementia, frontotemporal dementia, and corticobasal degeneration [An article from: Neuropsychologia] by S. Luzzi, J.S. Snowden, et all 2007-01
  6. Quantifier comprehension in corticobasal degeneration [An article from: Brain and Cognition] by C.T. McMillan, R. Clark, et all 2006-12-01
  7. Verbal mediation of number knowledge: Evidence from semantic dementia and corticobasal degeneration [An article from: Brain and Cognition] by C. Halpern, R. Clark, et all 2004-10-01
  8. Corticobasal degeneration: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Richard Robinson, 2005
  9. Gestural imitation and limb apraxia in corticobasal degeneration [An article from: Brain and Cognition] by J.E. Salter, E.A. Roy, et all 2004-07-01
  10. Alien Hand Syndrome: Cerebral hemisphere, Brain, Epilepsy, Neurosurgery, Stroke, Affordance, Utilization behavior, Environmental dependence syndrome, Neurophenomenology, ... Corticobasal degeneration, Neuroplasticity
  11. The Official Patient's Sourcebook on Corticobasal Degeneration A Revised and Updated Directory for the Internet Age by Philip M. Parker, 1980

1. Cortico Basal Ganglionic Degeneration
Corticobasal ganglionic degeneration (which we will call CBD) is a rare progressive neurological Di Maria et al. corticobasal degeneration shares a common genetic background with
http://www.neuro.nwu.edu/meded/MOVEMENT/corticobasal.html
Corticobasal ganglionic degeneration (CBD) Timothy C. Hain, MD Northwestern University Medical School, Most recent update: 7/2001 Please read our
Corticobasal ganglionic degeneration (which we will call CBD) is a rare progressive neurological disorder characterized by a combination of Parkinsonism and cortical dysfunction. It is a rare sporadic progressive disorder first reported in 1968. CBD appears to be closely related to another, less rare, sporadic extrapyramidal degenerative disorder named Progresive Supranuclear Palsy (PSP) . In CBD, cognitive symptoms dominate, while in PSP, eye movement symptoms dominate the picture. The Parkinsonism is generally an asymetric akinetic rigid syndrome, unresponsive to levodopa, similar to that of multiple system atrophy and PSP . Eye movement abnormalities are common, as in PSP, and a supranuclear gaze palsy can be seen as in PSP. Given the genetic similarities between CBD and PSP, it seems possible that they are simply two "faces" of the same disease. Neuroradiological imaging studies in CBD demonstrate cortical atrophy, which may be symmetrical or asymmetrical. Other cortical signs include

2. NINDS Corticobasal Degeneration Information Page
corticobasal degeneration information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). What is corticobasal degeneration?
http://www.ninds.nih.gov/health_and_medical/disorders/cortico_doc.htm
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Table of Contents (click to jump to sections) What is Corticobasal Degeneration?
Is there any treatment?

What is the prognosis?
What research is being done? ... Related NINDS Publications and Information What is Corticobasal Degeneration? Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Initial symptoms, which typically begin at or around age 60, may first appear on one side of the body (unilateral), but eventually affect both sides as the disease progresses. Symptoms are similar to those found in Parkinson disease, such as poor coordination, akinesia (an absence of movements)

3. WE MOVE - Corticobasal Degeneration Overview
corticobasal degeneration (CBD) is a rare neurological disease in which parts of the brain deteriorate or degenerate. corticobasal degeneration Overview.
http://www.wemove.org/cbd/cbd.html
WE MOVE
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Corticobasal Degeneration Overview
What is corticobasal degeneration?
Corticobasal degeneration (CBD) is a rare neurological disease in which parts of the brain deteriorate or degenerate. CBD is also known as corticobasal ganglionic degeneration, or CBGD. Several regions of the brain degenerate in CBD. The cortex, or outer layer of the brain, is severely affected, especially the fronto-parietal regions, located near the center-top of the head. Other, deeper brain regions are also affected, including parts of the basal ganglia, hence the name "corticobasal" degeneration. The combined loss of brain tissue in all these areas causes the symptoms and findings seen in people with CBD. Causes of Corticobasal Degeneration Our Mission Board of Directors Funders ... WE MOVE

4. Treatment Of Corticobasal Degeneration At Mayo Clinic
Mayo Clinic Medical Services corticobasal degeneration. Treatment of corticobasal degeneration at Mayo Clinic. (Synonyms Corticobasal
http://www.mayoclinic.org/corticobasaldegeneration/
Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Corticobasal Degeneration Corticobasal Degeneration Treatment Appointments Clinical Trials Research ... Medical Services
Treatment of Corticobasal Degeneration at Mayo Clinic
(Synonyms: Corticobasal syndrome (CBS), corticobasal ganglionic degeneration (CBGD), cortical-basal ganglionic degeneration (CBGD)) Corticobasal degeneration (often abbreviated CBD) is a degenerative disorder of the brain in which nerve cells die over time, causing a progressive decline in the ability to move and think. Symptoms include arm or leg incoordination, arm or leg stiffness, tremor, and gait unsteadiness. Some patients also suffer some decline in thinking ability such as forgetfulness, poor problem solving abilities and poor concentration. Although no cure for corticobasal degeneration yet exists, there are several medications as well as many non-medication approaches that can potentially improve daily functioning and quality of life. One of the keys to effective management is a coordinated approach to the treatment options. Mayo Clinic offers a multidisciplinary approach that involves a comprehensive evaluation of the patient's disease and associated symptoms by physicians who have extensive experience in the diagnosis and treatment of patients with corticobasal degeneration. These specialists include neurologists, neuropsychologists, neuroradiologists, psychiatrists, sleep medicine clinicians and physical medicine specialists. Treatment programs are tailored to each individual patient and take into account the patient's and family's needs while providing state-of-the-art care and access to new developments and appropriate clinical trials.

5. Corticobasal Degeneration
corticobasal degeneration is characterized by loss and atrophy of multiple areas of the brain, including the cerebral cortex and the basal ganglia. corticobasal degeneration. corticobasal degeneration is a progressive neurological disorder characterized
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Corticobasal Degeneration
Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Initial symptoms, which typically begin at or around age 60, may first appear on one side of the body (unilateral), but eventually affect both sides as the disease progresses. Symptoms include signs of parkinsonism such as poor coordination, akinesia (an absence of movements), rigidity (a resistance to imposed movement), and disequilibrium (impaired balance); and limb dystonia (abnormal muscle postures). Other symptoms such as cognitive and visual-spatial impairments, apraxia (loss of the ability to make familiar, purposeful movements), hesitant and halting speech, myoclonus, and dysphagia (difficulty swallowing) may also occur. The patient is unable to walk. Symptoms vary among patients.
Is there any treatment?

6. NORD - National Organization For Rare Disorders, Inc.
General Discussion. corticobasal degeneration is a rare progressive neurological disorder characterized by cell loss and The exact cause of corticobasal degeneration is unknown.
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Corticobasal

7. WE MOVE - Corticobasal Degeneration
corticobasal degeneration. »corticobasal degeneration Information for Patients and corticobasal degeneration Information for Medical Professionals at MDVU. corticobasal degeneration
http://www.wemove.org/cbd.html
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8. NINDS - News And Events
Sorry! There are no press releases for corticobasal degeneration. Use your browser s Back button to return to your previous activity.
http://www.ninds.nih.gov/health_and_medical/news.htm?url=/health_and_medical/dis

9. WE MOVE - Corticobasal Degeneration
corticobasal degeneration. » Corticobasal MDVU. corticobasal degeneration Information for Patients and Caregivers. Table of Contents.
http://www.wemove.org/cbd/
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E-mail: wemove@wemove.org
Corticobasal Degeneration
Corticobasal Degeneration Information for Patients and Caregivers Table of Contents WE MOVE makes every effort to present medical information that is up-to-date and accurate. The material provided has undergone rigorous medical review. Information regarding the authors, editors, publisher, and medical reviewers of this material of the WE MOVE Web site is listed below. Medical science is constantly changing. Therefore, the authors, editors, and publisher do not warrant that the information in this text is complete, nor are they responsible for omissions or errors in the text or for the results of the use of this information. This information does not replace consultation with a physician. All medical procedures, drug doses, indications, and contraindications should be discussed with your personal physician. Medical Editor: Richard Robinson
Medical Review: Oscar Gershanik, MD; Anthony E. Lang, MD

10. ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies:
Search results for corticobasal degeneration ALLFIELDS are shown below.
http://clinicaltrials.gov/search/term=Corticobasal Degeneration
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11. Treatment Of Corticobasal Degeneration, Mayo Clinic In Rochester, Minn.
Treatment of corticobasal degeneration at Mayo Clinic in Rochester. (Synonyms CBD, Corticobasal syndrome (CBS), corticobasal ganglionic
http://www.mayoclinic.org/corticobasaldegeneration-rst/
Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Corticobasal Degeneration Corticobasal Degeneration Treatment Appointments Clinical Trials Research ... Medical Services
Treatment of Corticobasal Degeneration at Mayo Clinic in Rochester
(Synonyms: CBD, Corticobasal syndrome (CBS), corticobasal ganglionic degeneration (CBGD), cortical-basal ganglionic degeneration (CBGD)) Corticobasal degeneration (often abbreviated CBD) is a degenerative disorder of the brain in which nerve cells die over time, causing progressive motor disabilities and cognitive decline. Symptoms include arm or leg incoordination, arm or leg stiffness, tremor, and gait unsteadiness. Some patients also develop some degree of cognitive impairment such as forgetfulness, poor problem solving abilities, and poor concentration. Although no cure for corticobasal degeneration yet exists, there are several medications as well as many non-medication approaches that can potentially improve daily functioning and quality of life. One of the keys to effective management is a coordinated approach to the treatment options.
Mayo Clinic's Experience with CBD
Mayo Clinic offers a multidisciplinary approach that involves a comprehensive evaluation of the patient's disease and associated symptoms by physicians who have extensive experience in the diagnosis and treatment of patients with corticobasal degeneration. These specialists include neurologists, neuropsychologists, neuroradiologists, psychiatrists, sleep medicine clinicians, and physical medicine specialists. Treatment programs are tailored to each individual patient and take into account the patient's and family's needs while providing state-of-the-art care and access to new developments and appropriate clinical trials.

12. NINDS Corticobasal Degeneration Information Page
corticobasal degeneration information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). What is corticobasal degeneration? corticobasal degeneration is a progressive neurological the cerebral cortex and the basal ganglia. corticobasal degeneration progresses gradually
http://accessible.ninds.nih.gov/health_and_medical/disorders/cortico_doc.htm
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    NINDS Corticobasal Degeneration Information Page
    Reviewed 3-21-2003 Get Web page suited for printing
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    Table of Contents (click to jump to sections)
    What is Corticobasal Degeneration?

    Is there any treatment?

    What is the prognosis?

    What research is being done?
    ...
    Related NINDS Publications and Information

    What is Corticobasal Degeneration?
    Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Initial symptoms, which typically begin at or around age 60, may first appear on one side of the body (unilateral), but eventually affect both sides as the disease progresses. Symptoms are similar to those found in Parkinson disease, such as poor coordination

    13. Introduction: Corticobasal Degeneration - WrongDiagnosis.com
    Introduction to corticobasal degeneration as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
    http://www.wrongdiagnosis.com/c/corticobasal_degeneration/intro.htm
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    Current chapter: Corticobasal Degeneration Next sections Basic Summary for Corticobasal Degeneration Prognosis of Corticobasal Degeneration Symptoms of Corticobasal Degeneration Complications of Corticobasal Degeneration ... Misdiagnosis of Corticobasal Degeneration Next chapters: Cytomegalic Inclusion Body Disease Infant Cytomegalic virus Dermatomyositis Dysgraphia ... Feedback
    Introduction: Corticobasal Degeneration
    Corticobasal Degeneration: Progressive brain damage usually in seniors. Corticobasal Degeneration: Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Contents for Corticobasal Degeneration: Footnotes: 1. excerpt from

    14. Corticobasal Degeneration
    corticobasal degeneration. corticobasal degeneration (CBD) is a slowly progressive neurodegenerative disorder characterized by an
    http://perso.wanadoo.fr/alzheimer.lille/corticobasal.degeneration.html
    Alzheimer Brain dis eases Research ... untington Hallenvorden IBM L ewy BD MSA NPiD c Parkinson D Guadeloupe Parkinson Dementia  in Parkinson Pick ... Semantic  D SSP
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    Corticobasal degeneration
    Corticobasal degeneration (CBD) is a slowly progressive neurodegenerative disorder characterized by an asymmetrical akinetic-rigid syndrome associated with cognitive (apraxia and aphasia) and extrapyramidal motor dysfunction (rigidity and dystonia). Moderate dementia emerges sometimes late in the course of the disease (Rinne et al., 1994). Key words: myoclonus, dystonia, alien limb, occulomotor apraxia Prevalence: 4.0 -7.3 /100.000 Incidence: 0.6-0.9 new cases per 100.000 person/year Neuropathology Neuropathological examination shows gliosis, neuronal loss, presence of achromatic ballooned neurons, neuritic changes and neurofibrillary tangles (Paulus et al., 1990 ; Ksiezak-Reding et al., 1994; Feany et al., 1994; Buée-Scherrer et al., 1996b) and astrocytic plaques. There is an overlap between progressive supranuclear palsy (PSP) and CBD (Feany et al., 1996), and it would be most helpful to distinguish these two pathologies on a neuropathological or immunochemical basis. By comparison, CBD is less prevalent, and usually dysplays a more severe cortical atrophy with fronto-parietal predominance partly sparing the central area.

    15. Corticobasal Degeneration

    http://perso.wanadoo.fr/alzheimer.lille/DCB.html
    Accueil Le laboratoire Maladie d'Alzheimer Autres maladies ... Base de donn³es
    D³g³n³rescence corticobasale
    English version: Corticobasal degeneration Aspects cliniques: Il s'agit d'une maladie neurod³g³n³rative relativement rare qui touche essentiellement les r³gions c³r³brales sous-corticales, puis corticales. Les ³l³ments les plus caract³ristiques sont un dysfonctionnement moteur asym³trique (apraxie de la main gauche), une perte sensorielle corticale, et une apraxie sans d³t³rioration intellectuelle ö ce stade. Mais le tableau clinique est souvent voisin de la Paralysie supranucl³aire Progressive (PSP ou Maladie de Steele -Richardson-Olszewski): r³sistance ö la L-dopa, tremblement d'attitude, syndrome pseudo-bulbaire avec dysarthrie, dysphagie, troubles oculomoteurs ainsi qu'une d³mence peuvent °tre associ³es.
    Neuropathologie:
    • On peut observer une d³g³n³rescence neurofibrillaire dans les noyaux sous corticaux ainsi que dans le cortex, et pr³f³rentiellement dans les r³gions frontales. Il y a ³galement une perte neuronale et une gliose. Il y a ³galement des cellules chromatolytiques (ou cellules de Pick, ö ne pas confondre avec les corps de Pick). Les r³gions les plus touch³es sont frontales et pari³tales. La DNF affecte ³galement les astrocytes pour former les "glial tangles" et les plaques astrocytaires. La technique de Gallyas (impr³gnation argentique optimale pour la DNF) rev²le des plaques astrocytaires en ³toile pour la PSP (tufted plaques), alors que pour la CBD, le marquage est plutªt en couronne (astroyctic plaques).

    16. Corticobasal Degeneration - Information / Diagnosis / Treatment / Prevention
    home neurological disorders brain diseases corticobasal degeneration corticobasal degeneration. Information • Diagnosis • Treatment • Prevention.
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    Health News: Search millions of published articles for news on Corticobasal Degeneration Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Caregivers Guide Guide for Corticalbasal Ganglionic Degeneration. Corticobasal Degeneration Information sheet compiled by the National Institute of Neurological Disorders and Stroke. Corticobasal Ganglionic Degeneration (CBGD) Article by Timothy C. Hain, MD from Northwestern University Medical School. Notes: Healthcyclopedia presents health information in the form of websites and articles that encompass conventional medicine and alternative treatments Under no circumstances can it recommend or endorse a specific drug or therapy or treatment.

    17. Pick's Disease Support Group - Frontal Lobe Degeneration, Pick's Disease Support
    corticobasal degeneration by Dr Basil Ridha, Dementia Research Group. What is corticobasal degeneration? Who may get affected by corticobasal degeneration?
    http://www.pdsg.org.uk/Booklet/cbdg.htm
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    Driving and Dementia Val Val's Journey Booklet - 2003 CorticoBasal Degeneration by Dr Basil Ridha, Dementia Research Group
    What is corticobasal degeneration?
    This is a rare progressive neurological disease that causes disturbance of mental processes and motor skills. The disease is named after the areas of the brain that are principally affected. Cortico refers to the cortex, which is the outer layer of the brain, and basal refers to the basal ganglia, which are deep structures in the brain that control motor skills. In these brain regions, there is more significant loss of brain cells than in normal aging. ~The cause of brain cell loss is not known, but there is excessive accumulation of a certain substance called tau protein. This also occurs in other similar neurological diseases such a progressive supranuclear palsy or PSP.
    Who may get affected by corticobasal degeneration?

    18. The Pick's Disease Support Group - Caregiver Stories: John
    corticobasal degeneration. John by John Lynne Dams. The presence of alien limb syndrome pointed to the diagnosis of corticobasal degeneration .
    http://www.pdsg.org.uk/Stories/John.htm
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    Messages Join YahooGroups Contacts Email Directory PDSG Phone Directory Articles Caregivers Home Alone Poetry Caregiver Stories: Corticobasal Degeneration John John worked for Rolls Royce (Aero Engines) at various jobs, retraining as a turner at the age of fifty-seven. Some said it was too much to take on at this time of life. However John coped well and was happy in his new job. We married in 1993, this being my second marriage; John was a bachelor who had lived with his elderly Mother. We cared for her jointly until her death in 1996 at the age of 86. John helped around the house cooking, washing up, gardening, DIY etc, we got on famously. He enjoyed playing golf and has won many trophies and cups. He also enjoyed motor cycle restoration and riding a bike of his own. At the age of fifty-eight John was offered early retirement, we thought about it and decided we could do so many things together, we enjoyed walking and had holidayed in Scotland, Yorkshire, and Lake District as well as locally; so John retired. However some eighteen months later at sixty John developed problems with his walking. His left leg, as if it was on a spring, would suddenly have a mind of its own. Also his left arm would rise on its own. He also experienced problems finding light switches and hammering and tightening screws when doing his DIY. Golf became harder as his hands would waver about for a few seconds and he had little control of the club. Also the grass looked vivid green and he had the feeling of it coming up towards him. He had weight loss - some two stone, along with this there was muscle loss and weakness. He lacked strength in everyday tasks, indeed some tasks became impossible.

    19. Neurology -- Collected Resources : Corticobasal Degeneration
    Institution Google Indexer Sign In as Individual. corticobasal degeneration. Citations 16 of 6 total displayed. Most recent content (13 Apr 2004)
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    Dissociation of numbers and objects in corticobasal degeneration and semantic dementia
    C. H. Halpern, G. Glosser, R. Clark, J. Gee, P. Moore, K. Dennis, C. McMillan, A. Colcher, and M. Grossman
    Neurology 2004; 62: 1163-1169. [Abstract] [Full text]
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    Pathologically confirmed corticobasal degeneration presenting with visuospatial dysfunction
    D.F. Tang-Wai, K.A. Josephs, B.F. Boeve, D.W. Dickson, J.E. Parisi, and R.C. Petersen
    Neurology 2003; 61: 1134-1135. [Abstract] [Full text]
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    Language function and dysfunction in corticobasal degeneration
    Naida L. Graham, Thomas Bak, Karalyn Patterson, and John R. Hodges

    20. Neurology -- Correspondence For Graham Et Al., 61 (4) 493-499
    Language function and dysfunction in corticobasal degeneration, 28 October 2003. Language function and dysfunction in corticobasal degeneration.
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    Naida L. Graham, Thomas H. Bak, Karalyn Patterson, and John R. Hodges (28 October 2003)
    Language function and dysfunction in corticobasal degeneration 28 October 2003 Andrew J. Larner,
    Walton Centre for Neurology and Neurosurgery
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