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         Cleidocranial Dysplasia:     more detail
  1. Cleidocranial dysplasia: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Jennifer, MS, CGC Roggenbuck, 2005

61. Characteristics Of Jaw Growth In Cleidocranial Dysplasia
35, No. 2, pp. 161–166. Characteristics of Jaw Growth in cleidocranial dysplasia. Kazuhiro Ishii, DDS Ib Leth Nielsen, DDS Karin Vargervik, DDS.
http://cpcj.allenpress.com/cpcjonline/?request=get-abstract&doi=10.1597/1545-156

62. Healthwise
Topic cleidocranial dysplasia, Back to previous page. cleidocranial dysplasia is a rare craniofacial disorder inherited as an autosomal dominant trait.
http://www.stlukes-sf.sutterhealth.org/health/healthinfo/index.cfm?section=healt

63. Molecular Mechanisms Of Cleidocranial Dysplasia
1079 Molecular Mechanisms of cleidocranial dysplasia. P. PAPAGERAKIS, and M. MACDOUGALL, University of Texas San Antonio / Health Science Ctr, USA
http://iadr.confex.com/iadr/2004Hawaii/techprogram/abstract_47822.htm
1079 Molecular Mechanisms of Cleidocranial Dysplasia P. PAPAGERAKIS , and M. MACDOUGALL, University of Texas - San Antonio / Health Science Ctr, USA Seq #114 - Genetic Polymorphism in Periodontal Diseases
10:15 AM-11:30 AM, Thursday, 11 March 2004 Hawaii Convention Center Exhibit Hall 1-2 Back to the Periodontal Research - Pathogenesis Program
Back to the IADR/AADR/CADR 82nd General Session (March 10-13, 2004)

64. Cleidocranial Dysplasia: Alteration Of Downstream Runx2 Genes In Periodontal Lig
1087 cleidocranial dysplasia Alteration of Downstream Runx2 Genes in Periodontal Ligament. I. GAY, S. CHEN, and M. MACDOUGALL, University
http://iadr.confex.com/iadr/2004Hawaii/techprogram/abstract_48188.htm
1087 Cleidocranial Dysplasia: Alteration of Downstream Runx2 Genes in Periodontal Ligament I. GAY , S. CHEN, and M. MACDOUGALL, University of Texas - San Antonio / Health Science Ctr, USA Cleidocranial Dysplasia (CCD) is an autosomal dominant disorder characterized by bone defects, supernumerary teeth, tooth hypoplasia and delayed root formation and tooth eruption. Mutations in the runt-related transcription factor 2 (RUNX2) are associated with this disorder. The molecular mechanisms that correlate RUNX2 mutations with the CCD dental phenotype, especially related to tooth eruption and root formation, remains obscure. Objective: To perform a broad survey of gene expression profiles in periodontal ligament (PDL) cells of CCD versus normal patients to identify critical RUNX2 down-stream target genes. Methods: Age matched normal and CCD PDL cells were established from primary explant cultures. Cells were characterized for cell proliferation, ALP activity, vonKossa staining and gene expression profiles. For genes differentially expressed samples were screened using an Affymetrix human genome U133 gene array. To confirm these results, quantitative real time PCR (QRT-PCR) was performed on selected transcripts. Finally gene promoter analysis was performed of potential RUNX2 target genes using the www.generegulation.com program. Results: Of the 39,000 transcripts tested by gene array, 5520 genes (14%) were up-regulated while 9462 (24%) were down-regulated in CCD as compared to normal PDL cells. The QRT-PCR data confirmed several of the significant differences. Key bone remodeling factors such as OPG increased 11.39 fold, while BMP 7 (1.13), BMP 6 (1.37), OSN (1.63), and RUNX2 (3.02) itself were down-regulated in CCD patients. Gene promoter analysis demonstrated at least one potential RUNX2 binding site for all putative genes analyzed.

65. ORPHANET - Rare Diseases - Orphan Drugs
Printing version, DISEASE Yunis varon syndrome, Synonym(s) cleidocranial dysplasia micrognathia absent thumbs, ICD Q87.8, No description is available,
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=3472

66. ORPHANET® Cleidocranial Dysplasia
ORPHANET. Orphanet database access. cleidocranial dysplasia. Direct access to data Clinical signs Autosomal dominant inheritance; Brachycephaly
http://www.orpha.net/static/GB/cleidocranialdysplasia.html

67. PillSupplier.com - Conditions And Diseases/Rare Disorders/Cleidocranial Dysplasi
Category cleidocranial dysplasia. HOME ABOUT US Login . Conditions and Diseases/Rare Disorders/cleidocranial dysplasia. Links A Natural
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68. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Rare_Disorders/Cle
Click Here. Top Health Conditions and Diseases Rare Disorders cleidocranial dysplasia (4 links). News about cleidocranial dysplasia
http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Rare_Disord
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Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Rare Disorders Cleidocranial Dysplasia (4 links) See Also: News about Cleidocranial Dysplasia Dog Genome Yields Information That May Benefit Human Health (May 21, 2004) full story Possible Link Discovered Between Gene Responsible For Blood Vessel Development And ACD In Newborns (March 12, 2004) full story Activation Of Receptor Ups Development Of Precancerous Intestinal Polyps (February 2, 2004) full story Hopkins Researchers Find Genetic Cause For Multi-system Disorder (January 2, 2003)

69. Conditions And Diseases: Rare Disorders: Cleidocranial Dysplasia| Treasure Coast
Information on Conditions and Diseases, Rare Disorders, cleidocranial dysplasia and much more Treasure Coast Health. Treasure Coast
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70. Cleidocranial Dysplasia From Linkspider UK Health Directory
cleidocranial dysplasia by Linkspider UK, cleidocranial dysplasia links and cleidocranial dysplasia topics from our Health directory.
http://linkspider.co.uk/Health/ConditionsandDiseases/RareDisorders/Cleidocranial
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71. Penn State Faculty Research Expertise Database (FRED)
Faculty Research Expertise Database. cleidocranial dysplasia. Dysostoses, Cleidocranial, Dysplasia, Cleidocranial. Dysplasias, Cleidocranial, Faculty Experts,
http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D002973

72. Cleidocranial Dysplasia
Home Up . Click Here! cleidocranial dysplasia. Click Here! Musice.net Just-recipes.net EnvyMag.com Scholarships-4u.com Shesearch
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73. Ccd - Cleidocranial Dysplasia
Features Listed For Ccd cleidocranial dysplasia. Chromosome MOUSE GENOME DATABASE (MGD).
http://www.hgmp.mrc.ac.uk/dhmhd-bin/mous-look-up?434

74. DrRecommend: Cleidocranial Dysplasia
Medical doctors review cleidocranial dysplasia electronic medical information resources available in any of the following media browsable WWW sites, or
http://www.drrecommend.com/lst/Health/Conditions_and_Diseases/Rare_Disorders/Cle
sitetype='health'; site='drrecommend.com'; barcategory='cleidocranial dysplasia'; barpath="http://drrecommend.com/lst/Health/Conditions_and_Diseases/Rare_Disorders/Cleidocranial_Dysplasia/"; Specials: American Express no-fee card pays back upto 5% cash. Vitamin Shoppe up to 75% off retail.
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75. FSP Syndromes
Lab Normal verylong-chain fatty acids. Syringomyelia cleidocranial dysplasia. from A Kornberg MD. Familial syringomyelia with Arnold
http://www.neuro.wustl.edu/neuromuscular/spinal/fsp.html

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FAMILIAL SPINAL CORD SYNDROMES
General principles
Familial Spastic Paraplegia ( SPG

Dominant

: Atlastin; 14q11
: Spastin; 2p22
SPG 12q

Recessive

: Paraplegin; 16q24
(Troyer): Spartin; 13q12.3
(Mast): Maspardin; 15q22 Infantile onset : Alsin; 2q33 X-linked : Proteolipid protein; Xq22 Other: Deafness Familial Spastic Paraplegia +... Ataxia CNS Ocular PNS ... Systemic Disorders Leukodystrophies Adrenomyeloneuropathy : ALDP; Xq28 Adult-onset Krabbe : GalC; 14q31 MLD : Arylsulfatase A; 22q13 Other spinal cord syndromes Syndromes AAA syndrome : Aladin; 12q13 Adrenomyeloneuropathy : ALDP; Xq28 Alexander : GFAP; 17q21; Dominant Alzheimer's : Presenilin 1; 14q24; Dominant Arnold-Chiari Malformation (SPG9): 10q23; Dominant Cavanagh's Cerebral palsy-Symmetrical Cerebrotendinous xanthomatosis : Cytochrome 450; 2q33 Charlevoix-Saguenay : Sacsin; 13q11 Deafness : X-linked DOPA-responsive dystonias DRPLA : DRPLA protein; 12p13; Dominant Episodic ataxia : 1p; Dominant Evans Fitzsimmons syndrome Friedreich ataxia : FRDA; 9q13 Hereditary Motor Syndromes HHH syndrome HMSN 5 : Dominant : ARX; Xp22

76. Cleidocranial Dysplasia
cleidocranial dysplasia. Does anyone have any info about children with cleidocranial dysplasia? What are the best sites and where can I find pictures of this?
http://www.specialchild.com/bbs3/messages/13297.html
This message was posted by Leah on February 29, 2004 at 12:12:43:
Cleidocranial dysplasia
Does anyone have any info about children with cleidocranial dysplasia? What are the best sites and where can I find pictures of this? They think that my 4 month old daughter might have this. Thank you!
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77. Quintessence Publishing
Issue 2. Back. Treatment of a Patient with cleidocranial dysplasia Using Osseointegrated Implants A Patient Report. Vicki C. Petropoulos
http://www.quintpub.com/journals/abstract.php3?iss2_id=119&article_id=1343

78. Entrez PubMed
Click here to read Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9

79. OMIM - #119600 CLEIDOCRANIAL DYSPLASIA; CCD
119600 cleidocranial dysplasia; CCD. See 168550 for a discussion of the combination of cleidocranial dysplasia and parietal foramina. Brueton et al.
http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?cmd=entry&id=119600

80. In Vivo Axial Forces And Bending Moments On Abutments
Treatment of a Patient with cleidocranial dysplasia Using Osseointegrated Implants A Patient Report. Vicki C. Petropoulos, DMD, MS
http://dentalimplants-usa.com/Research/Cleidocranial/Cleidocranial.html
Treatment of a Patient with Cleidocranial Dysplasia Using Osseointegrated Implants:
A Patient Report
Vicki C. Petropoulos, DMD, MS/Thomas J. Balshi, DDS/Stephen F. Balshi, BBE/Glenn J. Wolfinger, DMD
March/April , Volume 19, Issue 2
This patient report describes the treatment of a 42-year-old woman with cleidocranial dysplasia. Endosseous implants were used to restore the mandibular and maxillary arches with fixed prostheses. Six implants were placed in the mandible and immediately loaded with an acrylic resin fixed prosthesis. In the maxillary arch, 10 implants were submerged for 4 months prior to functional loading. A transitional denture was relined and placed in the maxilla 10 days after implant placement. Three months later, a definitive mandibular prosthesis was fabricated. The definitive maxillary restoration was delivered 6 months after surgery. The most recent follow-up, 6 months after delivery, confirmed a satisfactory treatment result to date. PDF FILE of Article Click here to see an Overview of Prosthodontics Intermedica
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