101. Imperial - Chronic Obstructive Pulmonary Disease (COPD) chronic obstructive pulmonary disease (COPD). Sebastian Johnston s group works on asthma and chronic obstructive pulmonary disease http://www1.imperial.ac.uk/medicine/research/iii/asthma/johnston/default.html

Quick Navigation Imperial home page A-Z of Departments Courses Research Alumni Tanaka Business School Faculty of Engineering Faculty of Life Sciences Faculty of Medicine Faculty of Physical Sciences Spectrum (restricted to College users) People finder Help Your browser does not support javascript or you have javascript turned off. Although this will not affect your accessibility to the content of this site, some of the advanced navigation features may not be available to you. Faculty of Medicine Research Infection and Immunity Asthma COPD Note: Some of the graphical elements of this site are only visible to browsers that support accepted web standards . The content of this site is, however, accessible to any browser or Internet device. »  ..up.. »  COPD Chronic obstructive pulmonary disease (COPD) Sebastian Johnston's group works on asthma and chronic obstructive pulmonary disease (COPD) and the role of respiratory viral infections in these diseases, with a particular interest in rhinovirus infections. The group carries out epidemiological investigations of the importance of environmental factors in development of these diseases and the role of viral and atypical bacterial infections in these diseases and in exacerbations. Cellular and molecular studies investigate the basic pathogenic mechanisms of the diseases and the role of viral and atypical bacteria in exacerbations with a major focus being the identification of targets for the development of new treatments. Clinical studies include experimental infection studies with rhinovirus and RSV and clinical trials of new therapeutic agents for asthma COPD and viral infections.

102. PBS - Who Cares: Chronic Illness In America -- Penny Day Penny Day Cutler, Ontario Hi, I have COPD which is chronic obstructive pulmonary disease. This disease is not very understood by the public. http://www.pbs.org/fredfriendly/whocares/your_stories/penny_day.html

Penny Day Cutler, Ontario Hi, I have COPD which is Chronic Obstructive Pulmonary Disease. This disease is not very understood by the public. I have a hard time just trying to get air into my lungs and some days it is a real challenge just to get dressed. It seems that people with this disease are not getting the information they need from the medical people to help them cope with this dreadful illness. I joined a support group, online called, EFFORTS, and that was the beginning of my real learning about COPD!!! This group is very supportive and is such a great resource for information. There is even a Respiratory Therapist and a doctor that belong to this group and give us so much correct information. I really believe that the public needs to be very much aware of this disease and what causes it. Smoking is the number one cause, but there is also an inherited kind. For a wonderful source of knowledge on COPD please check out the website!! I know that you will be very impressed with this support group. EFFORTS http://www.emphysema.net

103. Chronic Obstructive Pulmonary Disease News - Topix.net chronic obstructive pulmonary disease News. A research study of a oncedaily oral medication for COPD (chronic obstructive pulmonary disease). http://www.topix.net/health/chronic-obstructive-pulmonary-disease

Wednesday, June 2, 2004 Chronic Obstructive Pulmonary Disease News Search Medical Rollup Professional Nursing Obstetrics and Gynecology ... More Improve your site Add these news headlines to your website - click here Health and Environmental Advisory For Residents of Conimicut Point Health.state.ri.us - Wednesday May 26 - Exposure to hydrogen sulfide at this level can cause short-term health effects such as nausea, irritated eyes and throat-even in healthy people. Clinical Trials Update: May 24, 2004 Story.news.yahoo.com - Monday May 24 - Have questions about your health? Find answers here. A research study of an investigational medication for chronic bronchitis and emphysema, also known as chronic obstructive pulmonary ... See also: Chronic Bronchitis Ann Arbor, MI State agency releases health outcome report Business Jrnl.-Greater Tampa Bay - Friday May 21 - The report, entitled Chronic Obstructive Pulmonary Disease Hospitalizations, 1992-2002, provides information on hospitalization rates, in-hospital deaths, diagnoses and procedures for a ... See also: Chronic Bronchitis New Worry for Women: 20 Million Suffer from Chronic Lung Disease,...

104. Details For Acute Respiratory Failure In Chronic Obstructive Pulmonary Disease Acute Respiratory Failure in chronic obstructive pulmonary disease Cagle, Philip T.; Derenne, JeanPhilippe; Martin, Thomas R.; Nelson, Steven; Similowski http://www.bmjbookshop.com/shop/product_display.asp?productid=0824794877&product

105. Asthma / Chronic Obstructive Pulmonary Disease Research Centre Asthma / chronic obstructive pulmonary disease Research Centre. Events. International Symposium Airway Smooth Muscle in Pulmonary http://www.scrc.umanitoba.ca/Physiology/asthmacopd/

Asthma / Chronic Obstructive Pulmonary Disease Research Centre Events International Symposium: Airway Smooth Muscle in Pulmonary Pathophysiology May 3-4, 2000, Theatre B, BMSB, Bannatyne Campus Contact Dr. Andrew Halayko SCRC and Physiology WWW administrator: www@scrc.umanitoba.ca Revised April 19, 2000.

106. Chest: Mucin Apoprotein Expression In COPD - Chronic Obstructive Pulmonary Disea You are Here Articles Chest May, 2002 Article. Mucin apoprotein expression in COPD *.(chronic obstructive pulmonary disease) Chest, May, 2002, by George D http://www.findarticles.com/cf_0/m0984/5_121/87103263/p1/article.jhtml

@import url(/css/us/style.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); Advanced Search Home Help IN all publications this publication Health Automotive Business Computing Entertainment Health News Reference Sports YOU ARE HERE Articles Chest May, 2002 Content provided in partnership with Print friendly Tell a friend Find subscription deals Mucin apoprotein expression in COPD - chronic obstructive pulmonary disease Chest May, 2002 by George D. Leikauf Michael T. Borchers Daniel R. Prows Leigh G. Simpson Key words: airway; COPD; gene regulation; genetics; mucins; mucus hypersecretion; strain differences Abbreviations: DR = Dahl-resistant; DS = Dahl-sensitive; EGF = epidermal growth factor; EGFR = epidermal growth factor receptor; GalNAc = N-acetylgalactosamine; HETE = hydroxyeicosatetraenoic acid; IL = interleukin; kb = kilobase; MME = macrophage metalloelastase; MM[E.sup.+/+] = macro phage metalloelastase-competent; MM[E.sup.-/-] = macro phage metalloelastase-deficient; MMP = matrix metalloproteinase; mRNA = messenger RNA; PG[E.sub.2] = prostaglandin [E.sub.2]; PMA = phorbol 12-myristate 13-acetate; RT-PCR = reverse transcriptase-polymerase chain reaction; TFF = trefoil family factor; TGF = transforming growth factor; TNF = tumor necrosis factor; VNTR = variable-number tandem repeat [FIGURE 1 OMITTED] INFLAMMATION, CIGARETTE SMOKING, AND COPD

107. Emphysema And Chronic Obstructive Pulmonary Disease: Online Reference For Health Detailed definition of this disorder with a look at the causes, symptoms, diagnosis, prevention, complications and treatment. http://lef.org/protocols/prtcl-046.shtml

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108. Breathe Easy: A Guide To Living With COPD - TABLE OF CONTENTS Coping With Stress Eat to Feel Better. Living With COPD Energy Conservation in Dayto-Day Activities Travel and chronic Lung disease Sexuality. http://www.lung.ca/copd/tofc.html

TABLE OF CONTENTS The Impact of COPD in Canada What is COPD? Symptoms of COPD Causes of COPD ... How COPD Progresses Normal Lung Anatomy How Our Lungs Work Defence Mechanisms of the Lungs Abnormal Lung Anatomy Chronic Bronchitis Emphysema Asthma Preventative Management ... The Lung Association Resource Page

109. Hospital Course Asthma? Suggested Reading Matthay, RA. chronic Airway Diseases. Cecil Textbook of Medicine. 19th edition. WB Saunders Co, 1992, pp 386394. Murray, JF. http://www.meddean.luc.edu/lumen/MedEd/medicine/pulmonar/mdl/copd.htm

Review Case What type of acid-base disturbance occurred in the Emergency Room? What is the PA02? What is the A-a gradient and what does it tell you? Give at least two mechanisms of hypoxemia in this situation. What does the elevated HCO3 tell you? Spirometry revealed the following: FEV1 at 0100=0.5 L (pred 2.9 L); at 0800=0.7 L. FVC at 0100=Unobt. (pred 3.9 L); at 0800=1.7 L. Hospital Course Arterial blood gases are drawn in the Emergency Room and oxygen (2 LPM) by nasal prongs is started. Gases are repeated at 0300. You commence bronchodilators and begin trimethoprim/sulfamethoxazole. A gram stain of sputum reveals many PMN's and some alveolar macrophages. At 0800, the patient feels better, can raise some sputum and is able to sleep. Why begin trimethoprim/sulfamethoxazole? What are the most common pathogens in acute exacerbations of chronic bronchitis? Why did the PaC02 increase at 0300? Should any therapy be altered to diminish the hypercapnia? Should the patient be intubated? Note that the hypoxemia originally presented is easily corrected. What does this suggest as the mechanism of the hypoxemia?

110. Welcome To GOLD A list of objectives, documents and resources and registration for the guideline launch. http://www.goldcopd.com/

111. Informed Health Online Updated health information you can trust. http://www.informedhealthonline.org/item.aspx?topic=1175

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