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         Cerebral Gigantism:     more detail

41. Tillväxtavvikelser, Storvuxna Barn
Mätning av spontan GH insöndring på barnendokrinologisk enhet. F. cerebral gigantism (Soto s syndrom). Se OMIM (cerebral gigantism). II. HÖG VIKT.
http://www.internetmedicin.se/dyn_main.asp?page=679

42. SOTOS SYNDROME: A CASE REPORT:14(5)
Sotos syndrome (cerebral gigantism) is a rare form of accelerated growth in utero and in the first three to four years of life, after which it proceeds at a
http://www.kfshrc.edu.sa/annals/146/cr9400.html
November 1994
SOTOS SYNDROME: A CASE REPORT
Mohammed Alhumaidi, MD Address reprint requests and correspondence to Dr. Alhumaidi: Assistant Professor, College of Medicine, King Saud University, Abha Branch, P.O. Box 641, Abha, Saudi Arabia. Accepted for publication 2 May 1994. A four-year-old Saudi male was seen in the Endocrine Clinic of Asir Central Hospital because of a voracious appetite and excessive gain in weight. On examination, he had the typical phenotypic features of Sotos syndrome which included accelerated growth with height and weight more than three standard deviations (SD) above the mean. He had coarse facial features, prominent forehead, macrocephaly, large ears, hypertelorism and aplethoric face. He was frequently aggressive with advanced bone age of five years and magnetic resonance imaging (MRI) of the brain indicated widening of the lateral ventricles. He had no features to suggest other forms of overgrowth such as Marfan syndrome, McCune-Albright syndrome or homocystinuria. Endocrine causes of excessive weight gain due to pituitary or adrenal hyperfunction have been ruled out by biochemical tests, computed tomography (CT), and MRI. We document the first case report of Sotos syndrome from Saudi Arabia.

43. Dictionary Definition Of CEREBRAL GIGANTISM
Displaying dictionary terms starting with letter CE decortication cerebral dominance cerebral dysplasia cerebral embolism and thrombosis cerebral fissures cerebral flexure cerebral gigantism cerebral haematoma
http://www.dictionarybarn.com/CEREBRAL-GIGANTISM.php
Dictionary definition of CEREBRAL GIGANTISM
Browse Dictionary by alphabet A B C D ... Z Top Words Ce
ceasmic teratosis

cebidae

cebinae
...
cell nucleolus

A syndrome characterised by increased birth weight and length (above 90th percentile), accelerated growth rate for the first 4 or 5 years without elevation of serum growth hormone levels, and then reversion to normal growth rate; characteristic facies include prognathism, hypertelorism, antimongoloid slant, and dolichocephalic skull; moderate mental retardation and impaired coordination are also associated.
See: Sotos' syndrome.
Please select first two letters of word you are looking for CA CB CC CD ... CZ fiSearchFormMaxSetId='AX006027'; Top Words cell nucleus
cell organelle

cell physiology

cell plate
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44. Birth Disorder Information Directory - N
See Granulomatous Disease, Chronic, Autosomal Cytochromeb-Positive Form, Type II. Nevo Syndrome (cerebral gigantism, Nevo Type)
http://www.bdid.com/defectn.htm

HOME
N
N-Acetylglutamate Synthetase Deficiency N5-Methylhomocysteine Transferase Deficiency NADH-CoQ Reductase

45. Birth Disorder Information Directory - CO-CZ
Cramer Niederdellmann Syndrome (cerebral gigantism Jaw Cysts) cerebral gigantism jaw cysts. Crane Heise Syndrome (Cleft Lip/Palate
http://www.bdid.com/defectco.htm

HOME
Co-Cy
COACH Syndrome Coarctation of (the) Aorta (CoA) Coats' Disease (Congenital Retinal Telangiectasia, Exudative Retinitis, Leber Miliary Aneurysm) Cobb Syndrome Cocaine Antenatal Infection Cochin Jewish Disorder (Haim Munk Syndrome, Keratosis Palmoplantaris Periodontopathia) Cockayne Syndrome COD-MD Syndrome CODAS Syndrome (Cerebrooculodentoauriculoskeletal Syndrome) Coffin Syndrome (Arthritis Short Stature Deafness) Coffin-Lowry Syndrome Coffin Siris Syndrome (Fifth Digit Syndrome) COFS Syndrome Cohen Hayden Syndrome (Proteus-Like Syndrome with Mental Retardation and Eye Defects) Cohen Lockood Wyborney Syndrome (Blepharophimosis Ptosis Syndactyly Mental Retardation) Cohen Syndrome Colavita Kozlowski Syndrome (Short Limb Dwarf, Lethal Colavita Kozlowski Type)

46. Mental Health Alcoholic Liver Symptom Sunburg Cerebral Gigantism First Aid Medic
disease connective tissue diseases laws see legislation health information. medical service teen smoking huntingtons people picture
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disease connective tissue diseases laws see legislation health information
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47. Sotos Syndrome See Cerebral Gigantism Public Health Medical Resource Crack Cocai
chagas in influence sex medical research county department health medicaid. health prevention chicago education health society for
http://www.healthobservance.us/pagets-photo-wellness_569580.html
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48. Cerebral Gigantism Human Services Communicable Prevention First Aid Express Long
epsteinbarr virus see chronic fatigue syndrome prevention disease injury running. human services food health diet orthokeratology
http://www.health-observance.com/health-test-chagas_203319.html
epstein-barr virus see chronic fatigue syndrome prevention disease injury running
nutrition-and-dental-health genetic-eye-prevention sexually-transmitted-treatment-mental-health aids-hiv-in-role-youth-health-education ...
conditions chat parkinsons room

49. Gigantism
Other forms of excessive growth include cerebral gigantism, elephantoid hypertrophy of an entire limb or finger in neurofibromatosis, local soft tissue and
http://www.amershamhealth.com/medcyclopaedia/medical/Volume III 1/GIGANTISM.ASP
Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Gigantism, abnormal size and stature attributable to excessive growth, such as that occurring in the immature skeleton in hyperpituitarism . When the growth plates have not yet closed, direct hormonal stimulation of endochondral bone formation takes place, leading to proportional increase of bones in both length and width. The overgrowth of bones from hypersecretion of growth hormone that occurs after the growth plates have fused is termed acromegaly ; this abnormality affects predominantly the hands, feet and lower jaw. Other forms of excessive growth include cerebral gigantism, elephantoid hypertrophy of an entire limb or finger in neurofibromatosis , local soft tissue and bone gigantism in Klippel Trenaunay Weber syndrome macrodystrophia lipomatosa and lipoatrophic diabetes . The radiographic differential diagnosis of localized gigantism includes both congenital and acquired causes. The latter include dactylitis secondary to infection, trauma, infarction, Stills disease osteoid osteoma and melorheostosis
DR
The Encyclopaedia of Medical Imaging Volume III:1
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50. Neonatology On The Web: Macrencephaly
Much sporadic cases include macrencephaly with chromosomal disorder (XXYKlinefelter s syndrome). cerebral gigantism, Beckwith s Syndrome, and Achondroplasia.
http://www.neonatology.org/syllabus/macrencephaly.html
Neo Home New Clinical Computers ... Links
Teaching Files:
Macrencephaly
Division of Neonatology, Cedars-Sinai Medical Center, Los Angeles, California.
Anatomical Abnormality
The designation macrencephaly signifies a large brain and is a feature of heterogenous group of disorders that have not been well defined. Nevertheless, there are several entities in which the brain is generally well formed but is usually large.
  • Familial, isolated macrencephaly
    • Autosomal dominant
    • Autosomal recessive
  • Sporadic, isolated macrencephaly
  • Cerebral gigantism
  • Beckwith's syndrome
  • Achondroplasia
  • Neurocutaneous syndromes
    • Multiple hemangiomatosis
    • Pseudopapilledema
    • Asymmetrical hypertrophy +/- scoliosis (Klippel-Trenaunay-Weber)
    • Lipomas, lymphangiomas
    • Asymmetrical hypertrophy, +/- scoliosis, telangiectatic lesions, flame nevus of face (cutis marmorata telangiectatica congenita)
    • Neurofibromatosis
  • Unilateral macrencephaly
Timing and Clinical Aspects
Although neuronal proliferation in the cerebrum is an event that occurs pricipally during the second to fourth months of gestation, it is possible that this time period is prolonged in disorders of excessive proliferation. Alternatitively, the abnormal proliferation may occur at the appropriate time during development but at an excessive rate. The clinical syndrome in the several types of macrencephaly varies from no apparent neurological defecit (e.g., autosomal dominant, isolated macrencephaly) to severe recalcitrant seizures and mental retardation (e.g., unilateral macrencephaly, autosomal recessive, isolated macrencephaly). In other types of disorder, extraneural features may dominate the clinical picture (e.g., Beckwith's syndrome, and certain neurocutaneous syndromes). Note that although macrocephaly i.e., large head, accompanies these disorders, many other causes of macrocephaly in the newborn must be distinguished, e.g., hydrocephalus, large brain secondary to such disorders as Alexander's or Canavan's leukodystrophies, subdural hematoma, and large skull as in certain congenital hemolytic anemias or cranioskeletal dysplasia.

51. Entrez PubMed
Familial Sotos syndrome (cerebral gigantism) craniofacial and psychological characteristics. Bale AE, Drum MA, Parry DM, Mulvihill JJ.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?holding=npg&cmd=Retrieve&db=PubMed

52. Entrez PubMed
Letter cerebral gigantism. Townes PL. MeSH Terms Genes, Recessive; Gigantism/genetics*. PMID 1271433 PubMed indexed for MEDLINE
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?holding=npg&cmd=Retrieve&db=PubMed

53. Neuroguide.com - Human Neurological Diseases
Web sites providing information on human neurological diseases can be accessed via this section. cerebral gigantism. Soto s Syndrome Information (NINDS).
http://www.neuroguide.com/cgi-bin/pdistoc.pl?file=CerebralGigantism

54. NINDS Soto's Syndrome Information Page
Contact us Content for this page. NINDS Soto s Syndrome Information Page. Synonym(s) cerebral gigantism. Reviewed 0701-2001 Get
http://accessible.ninds.nih.gov/health_and_medical/disorders/sotos.htm
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    NINDS Soto's Syndrome Information Page
    Synonym(s): Cerebral Gigantism Reviewed 07-01-2001 Get Web page suited for printing
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    Table of Contents (click to jump to sections)
    What is Soto's Syndrome?

    Is there any treatment?

    What is the prognosis?

    What research is being done?
    ...
    Organizations

    What is Soto's Syndrome?
    Soto's syndrome is a rare genetic disorder characterized by excessive physical growth during the first 2 to 3 years of life. The disorder may be accompanied by mild mental retardation, delayed motor, cognitive, and social development, hypotonia (low muscle tone), and speech impairments. Children with Soto's syndrome tend to be large at birth and are often taller, heavier, and have larger heads (macrocrania) than is normal for their age. Symptoms of the disorder, which vary among individuals, include a disportionately large and long head with a slightly protrusive forehead, large hands and feet, hypertelorism (an abnormally increased distance between the eyes), and downslanting eyes. Clumsiness, an awkward gait, and unusual aggressiveness or irritability may also occur. Although most cases of Soto's syndrome occur sporadically, familial cases have also been reported.

    55. List Of Rare Diseases Starting With C
    phosphaturia; Cerebral cavernous malformation; Cerebral cavernous malformations; cerebral gigantism jaw cysts; cerebral gigantism; Cerebral
    http://www.fact-index.com/l/li/list_of_rare_diseases_starting_with_c.html
    Main Page See live article Alphabetical index
    List of rare diseases starting with C
    This list of rare diseases was originally taken from the NIH public domain resource at http://ord.aspensys.com/asp/diseases/diseases.asp A B C D E F G ... Z
    • C syndrome C1 esterase deficiency, (type 2 with ascites) Cacchi Ricci disease CACH syndrome Cacophobia Cafe au lait spots syndrome Caffey disease CAHMR syndrome Calcinosis-Raynaud phenomenon-sclerodactyly-telangiectasia Calciphylaxis Calculi Calderon Gonzalez Cantu syndrome Calloso genital dysplasia Callus disease Calpainopathy Calvarial hyperostosis Camera Marugo -Cohen syndrome Camfak syndrome Campomelia Cumming type Camptobrachydactyly Camptocormism Camptodactyly fibrous tissue hyperplasia skeletal dysplasia Camptodactyly joint contractures facial skeletal dysplasia Camptodactyly overgrowth unusual facies Camptodactyly syndrome Guadalajara type 1 Camptodactyly syndrome Guadalajara type 2 Camptodactyly taurinuria Camptodactyly vertebral fusion Camptomelic syndrome Camurati Engelmann disease Canavan leukodystrophy Candidiasis familial chronic Canga's bead symptom Cantalamessa Baldini Ambrosi syndrome Cantu Sanchez Corona Fragoso syndrome Cantu Sanchez Corona Garcia syndrome Cantu Sanchez Corona Hernandes syndrome Capillary leak syndrome with monoclonal gammopathy Capillary venous leptomeningeal angiomatosis Capos syndrome Caratolo Cilio Pessagno syndrome Carbamoyl phosphate synthetase deficiency Carbamoyl-phosphate synthase I deficiency disease (ornithine carbamoyl phosphate deficiency)

    56. List Of Neurological Disorders
    pontine myelinolysis; Cephalic disorder; Cerebral aneurysm; Cerebral arteriosclerosis; Cerebral atrophy; cerebral gigantism; Cerebral palsy;
    http://www.fact-index.com/l/li/list_of_neurological_disorders.html
    Main Page See live article Alphabetical index
    List of neurological disorders
    This is a list of major and frequently observed neurological disorders (e.g. Alzheimer's disease ), symptoms (e.g. back pain ), signs (e.g. aphasia ) and syndromes (e.g. Aicardi syndrome). A B C D ... Z
    A
    B
    C

    57. Wuup.de - /Health/Conditions_and_Diseases/Genetic_Disorders/Soto
    the prognosis. » Soto s Syndrome Also known as cerebral gigantism, an information sheet compiled by NINDS. » Sotos Syndrome
    http://wuup.de/index.php/Health/Conditions_and_Diseases/Genetic_Disorders/Soto's

    58. List Of Diseases: C - WrongDiagnosis.com
    atherosclerosis see Cerebral Arteriosclerosis; Cerebral Atrophy; cerebral gigantism see Soto s Syndrome; Cerebral haemorrhage
    http://www.wrongdiagnosis.com/lists/condsc.htm
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    List of Diseases: C
    A B C D ... Z
    C
  • C. neoformans ... see Cryptococcosis
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  • C. neoformans var. neoformans ... type of Cryptococcosis
  • C. pneumoniae ... see Chlamydia pneumoniae
  • CAD ... see Coronary heart disease
  • CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) ... type of Multi-Infarct Dementia
  • Caesarian Section
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  • Calcaneofibular ligament sprain ... type of Ankle sprain
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  • Calcinosis
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  • Calcium stone ...
  • 59. Medical Dictionary: C - WrongDiagnosis.com
    Central deafness; Cephalalgia; CERCLA; Cerebral; Cerebral atherosclerosis; cerebral gigantism; Cerebral haemorrhage; Cerebrovascular accident;
    http://www.wrongdiagnosis.com/lists/dictc.htm
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    A B C D ... Z
    C
  • C-peptide
  • C. pneumoniae
  • CAD
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  • 60. Sotos Syndrom - Små Och Mindre Kända Handikappgrupper
    Sotos syndrom. cerebral gigantism. Innehåll. Wit JM, Beemer FA, Barth PG et al. cerebral gigantism (Sotos syndrome). Compiled data of 22 cases.
    http://www.sos.se/smkh/1997-29-020/1997-29-020.htm
    Socialstyrelsen
    106 30 Stockholm
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    Socialstyrelsen klassificerar sin utgivning i olika dokumenttyper
    Sotos syndrom
    Cerebral gigantism
    Sjukdom/skada/diagnos
    Orsak till sjukdomen/skadan

    Symtom

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    ...
    Databasreferenser
    Dokumentdatum: 2002-02-25
    Version: 3.0
    Artikelnummer: 1997-29-020 Socialstyrelsen Detta är ett utdrag ur Socialstyrelsens kunskapsdatabas om små och mindre kända handikappgrupper. Med små och mindre kända handikappgrupper avses ovanliga sjukdomar/skador som leder till omfattande funktionshinder och som finns hos högst 100 personer per miljon invånare. Syftet med databasen är att ge aktuell information om små och mindre kända handikappgrupper och om det stöd och den service som dessa grupper behöver. För ytterligare information om aktuell diagnos hänvisas till informationsmaterial, litteratur och databaser som anges under resp diagnos.
    Sjukdom/skada/diagnos
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