21. Central Pontine Myelinolysis central pontine myelinolysis,. Print this article, central pontine myelinolysis, Fig. 1. MR, T2weighted axial image of the posterior fossa. http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 1/CENTRAL PONTINE

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Central pontine myelinolysis, (also called osmotic demyelination), demyelinating disorder found in alcoholics or in association with many systemic disorders with electrolyte abnormalities. Because of the common association with rapidly corrected hyponatraemia, the term "osmotic demyelination syndrome" has been proposed. The symptoms of central pontine myelinolysis are quadriparesis, pseudobulbar palsy and changing levels of consciousness, including coma and death. Histologically, the area of myelin breakdown is sharply demarcated and displays extensive loss of oligodendrocytes, infiltration with foamy macrophages and reactive astrocytosis. At MR the lesion is characterized by T2 hyperintensity in a central pontine location ( Fig.1 ); gadolinium enhancement may sometimes be present. Extrapontine sites of myelinolysis in the basal ganglia and midbrain, and subcortical white matter may also occur. Many entities can be considered in the differential diagnosis, including ischaemia, multiple sclerosis, encephalitis, toxic exposures, radiation therapy effects and brain stem gliomas. When present, the key to the MRI diagnosis is the bilateral involvement of the deep and capsular white matter, often accompanied by abnormalities in the thalami and basal ganglia.

22. Myelinolysis, Central, Pontine Other characters, Myelinolysis, central, pontine,. Print this article, see central pontine myelinolysis. GS. The Encyclopaedia of Medical Imaging Volume VI1. http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 1/MYELINOLYSIS CE

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Myelinolysis, central, pontine, see central pontine myelinolysis GS The Encyclopaedia of Medical Imaging Volume VI:1 Contacts GE Healthcare Making Waves

23. Central Pontine Myelinolysis - Encyclopedia Article About Central Pontine Myelin encyclopedia article about central pontine myelinolysis. central pontine myelinolysis in Free online English dictionary, thesaurus and encyclopedia. http://encyclopedia.thefreedictionary.com/Central pontine myelinolysis

Dictionaries: General Computing Medical Legal Encyclopedia Central pontine myelinolysis Word: Word Starts with Ends with Definition Central pontine myelinolysis is a neurologic disease caused by severe damage of the myelin sheath In neuroscience, myelin is an electrically insulating fatty layer that surrounds the axons of many neurons, especially those in the peripheral nervous system. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. The main consequence of a myelin layer (or sheath ) is an increase in the speed at which impulses propagate along the myelinated fiber. Along unmyelinated fibers impulses move continuously as waves, but in myelinated fibers they hop (or "propagate by saltation"). When a fiber is severed, the myelin sheath provides a track along which regrowth can occur. Unmyelinated fibers do not regenerate. Click the link for more information. of nerve cells Neurons (also called nerve cells ) are the primary cells of the nervous system.

24. Central Pontine Myelinolysis central pontine myelinolysis. toxic demyelination; rapid correction of hyponatremia. low density in central pons variable size; may http://chorus.rad.mcw.edu/doc/00066.html

CHORUS Collaborative Hypertext of Radiology Nervous system Feedback Search central pontine myelinolysis toxic demyelination rapid correction of hyponatremia low density in central pons variable size may have paired, rounded lesions enhances in acute phase See also: demyelinating diseases white-matter diseases Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 26 May 2004 Medical College of Wisconsin

25. Central Pontine Myelinolysis From Linkspider UK Health Directory central pontine myelinolysis by Linkspider UK, central pontine myelinolysis links and central pontine myelinolysis topics from our Health directory. http://linkspider.co.uk/Health/ConditionsandDiseases/NeurologicalDisorders/Brain

Match » -All words -Any word -Exact text Search » The Web Jobs / Vacancy Images / Photos FTP / Downloads United Kingdom United States of America Argentina Austria Australia Bangladesh Belgium Bolivia Brazil Bulgaria Canada Chile China Cuba Cyprus Czech Republic Czechoslovakia Denmark Dominican Republic Ecuador Egypt Estonia Finland France Germany Ghana Greece Hong Kong Hungary Iceland India Indonesia Ireland Israel Italy Japan Jordan Kenya Kuwait Latvia Lithuania Luxembourg Malaysia Malta Mexico Moldavia Monaco Morocco Mozambique Nepal Netherlands New Zealand Nicaragua Nigeria North Korea Norway Pakistan Panama Paraguay Peru Philippines Poland Portugal Qatar Romania Russian Federation Saudi Arabia Singapore South Africa South Korea Spain Sri Lanka Sweden Switzerland Taiwan Tanzania Thailand Tunisia Turkey Ukraine United Arab Emirates Uruguay Venezuela Yemen Yugoslavia Zambia Zimbabwe Ranking » On (no duplicate) Off (allow duplicate) Add my Site Toolbar Affiliates Directory Topic Central Pontine Myelinolysis assoicated to Health Directory Tree: Top Health Conditions and Diseases Neurological Disorders ... Metabolic : Central Pontine Myelinolysis ( See Also: Health: Conditions and Diseases: Neurological Disorders: Demyelinating Diseases Searching for central pontine m...?

26. Central Pontine Myelinolysis - General Practice Notebook central pontine myelinolysis. central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting long tract http://www.gpnotebook.co.uk/cache/-1583742920.htm

central pontine myelinolysis Central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting: long tract fibres pontocerebellar fibres pontine nuclei CPM is associated with: chronic alcoholism over-rapid correction of hyponatraemia There is no treatment. Click here for more information...

27. Central Pontine Myelinolysis - General Practice Notebook central pontine myelinolysis. Medical search. central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting http://www.gpnotebook.co.uk/medwebpage.cfm?ID=-1583742920

28. Central Pontine Myelinolysis CPM central pontine myelinolysis, central pontine myelinolysis in an alcoholic patient with an admitting serum sodium of 160 (normal up to 145). http://uscneurosurgery.com/glossary/c/cpm.htm

29. Neurological Disorders, Brain Diseases, Metabolic, Central Pontine Myelinolysis More central pontine myelinolysis Categories » Submit Your Site to the central pontine myelinolysis category. Sponsored central pontine myelinolysis Sites. http://www.iseekhealth.com/central_pontine_myelinolysis-1953.php

Home About Us Contact Submit Your Site Search : Home Health Conditions and Diseases Neurological Disorders ... Central Pontine Myelinolysis More Central Pontine Myelinolysis Categories: Submit Your Site to the Central Pontine Myelinolysis category Sponsored Central Pontine Myelinolysis Sites Brain Disease. Is It Alzheimer's? Alzheimer's is a disease of the brain. It makes it hard for people to remember, think, and use language. It can also make it difficult to do daily tasks like using the phone and cooking. But early treatment may help. Learn how to spot early symptoms. Fully searchable traditional medicine and alternative medicine books, videos and products for doctors, students and the public. An affiliate of Amazon.com. PCBs May Cause Brain Damage and Memory Problems Because PCBs damage the thyroid gland, scientists believe PCBs may damage the brain and cause memory problems, along with altered thyroid hormone levels. Drkoop: Medical Encyclopedia - A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. E-Medicine - Central Pontine Myelinolysis: An introduction, clinical features, differencials, work up, treatment and follow up.

30. Disease - Central Pontine Myelinolysis - Hartford, Connecticut , Saint Francis C Disease central pontine myelinolysis - courtesy of Saint Francis Care of Hartford, Connecticut, contemporary medicine with major clinical concentrations in http://www.saintfranciscare.com/11389.cfm

@import url(main.css); About Us Health Information Adam Article Manager CareMail Signup ... Ways To Help Adam Article Manager Back Back to main Health Information page Disease - Central pontine myelinolysis Central nervous system Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes And Risk: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.

31. Central Pontine Myelinolysis Subject central pontine myelinolysis Topic Area Myelin Forum The Neurology and Neurosurgery Forum Question Posted By Ottilie on Saturday, March 04, 2000 http://www.medhelp.org/forums/neuro/messages/30435a.html

Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: central pontine myelinolysis Topic Area: Myelin Forum: The Neurology and Neurosurgery Forum Question Posted By: Ottilie on Saturday, March 04, 2000 Would like to know if any research is being done on this disease on the brain stem (pons). I have it plus it has caused down beat nystagmus which prevents me from driving. The psychological impact is terrible. I also would like to find someone with this disease. So far I have not. Answer Posted By: CCF Neuro[P] MD, RPS on Saturday, March 04, 2000 Dear Ottilie: Central pontine myelinosis is usually results from changes in the osmolarity (electrolyte and protein concentration) in the brain versus the blood stream. The abnormal difference between the two causes the myelin surrounding the nerve processes to become unraveled. This inturn causes dysfunction of the nerves in this area. This is not a disease, but the result from an abnormality. Pontine problems can also arise from stroke in the pons. This will give similar symptoms (although much more focal, such as only downbeat mystagmus). If the stroke is large enough, it can cause complete loss of most movement below the eyes.

32. Central Pontine Myelinolysis Subject central pontine myelinolysis Topic Area Traumatic Brain Injury Forum The Neurology and Neurosurgery Forum Question Posted By gsoh on Monday http://www.medhelp.org/forums/neuro/messages/30819a.html

Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Central Pontine Myelinolysis Topic Area: Traumatic Brain Injury Forum: The Neurology and Neurosurgery Forum Question Posted By: gsoh on Monday, September 25, 2000 Her cognitive abilities were not affected albeit minor behavioral change. She has improved from assisted standing to self-gait walking (500 meters) over 6 weeks. Able to stand up on her own from a few limited sitting positions. Her right hand is able to hold a small cup of water. Taking a deep breath to hold on is still a difficulty. Rollover on bed is still very difficult. The strongest part of the four limbs at right leg is still having difficulty for coordinated movement. She was discharged on 23/8/00 and being 24 hours attended in the home. I am obviously more interested to know any chances of speeding up the process of re-myelination before it is too late. I started reading about the myelin reformation. Unfortunately, I cannot find any resources that confirm positively the process in adult brain cells. Nor is there any authority to rule out the process or point to the timing of a brain damage like CPM or other brain disorders. I started giving her Omega-3 oil, colloidal form minerals, Vitamin B6, B12. I read about IgG that may act with adult Oligodendroglia for the re-myelination process. So I give her chewable tablets of colostrums which contained high concentration of Immunoglobulin G. All these, being health food supplements, in my mind, should have minimal side effects.

33. Central Pontine Myelinolysis- Medcohealth.com central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?topicID=HE:Dise

34. Singapore Medical Journal In a patient with a history of sodium replacement, this finding is in keeping with osmotic myelinolysis (or central pontine myelinolysis). http://www.sma.org.sg/smj/4101/articles/4101me1ans.htm

Journals Present Issue Past Issues THESMANEWS Present Issue Past Issues SMJ Editorial Board Letters to the Editor Instructions to Authors S I N G A P O R E M E D I C A L J O U R N A L This site is supported by Health ONE Singapore Med J 2000; Vol 41(1): Clinics in Diagnostic Imaging (45) C Y Chan, H S Lam, J R Jinkins IMAGE INTERPRETATION MR scans showede a 1 cm area of T2 hyperintensity in the central pontine region (Fig 1a) . In a patient with a history of sodium replacement, this finding is in keeping with osmotic myelinolysis (or central pontine myelinolysis). Multiple areas of T2 hyperintensity were seen in the basal ganglia and deep white matter (Fig 1b) , representing part of the same process. DIAGNOSIS Osmotic myelinolysis (central pontine myelinolysis) CLINICAL COURSE The patient did not improve clinically over the following months. She developed spastic tetraparesis, pseudobulbar palsy and horizontal nystagmus. Because of mutism, antidepressants were tried but they were not effective. She remained bed-ridden and ventilator-dependent. During her hospital stay, she developed several episodes of chest and urinary tract infection which were controlled with antibiotics. The patient finally died one year later due to multiple organ failure and sepsis. DISCUSSION Osmotic myelinolysis (OM) is a demyelinating disease that can develop following rapid correction of hyponatremia from any cause. It was originally described in chronic alcoholics. Other reported associations include malnourished status, renal failure, diabetes mellitus, and post-orthotopic liver transplantation

35. REFERENCES central pontine myelinolysis clinical and MRI correlates. Postgrad Med J 1995; 7143042. Reversal of MR findings of central pontine myelinolysis. http://www.sma.org.sg/smj/4101/references/4101me1ref.htm

REFERENCES Ho VB, Fitz CR, Yoder CC, Geyer CA. Resolving MR features in osmotic myelinolysis (central pontine and extrapontine myelinolysis). AJNR 1993; 14:163-7. Martin PJ, Young CA. Central pontine myelinolysis: clinical and MRI correlates. Postgrad Med J 1995; 71:430-42. Laaureno R, Karp BI. Myelinolysis after correction of hyponatremia. Ann Intern Med 1997; 126:57-62. McGraw P, Edwards-Brown MK. Reversal of MR findings of central pontine myelinolysis. J Comput Assist Tomogr 1998; 22:989-91. Gregorio L, Sutton CL, Lee DA. Central pontine myelinolysis in a previously healthy 4-year-old child with acute rotavirus gastroenteritis. Pediatrics 1997; 99:738-43. Karp BI, Laureno R. Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia. Medicine (Baltimore) 1993; 72:359-73. Korogi Y, Takahashi M, Shinzato J, Sakamoto Y, Mitsuzaki K, Hirai T, et al. MR findings in two presumed cases of mild central pontine myelinolysis. AJNR 1993; 14:651-4. Gocht A, Colmant HJ. Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 1987; 6:262-70.

36. :: Ez2Find :: Central Pontine Myelinolysis Guide central pontine myelinolysis, Global Metasearch Any Language Guides, central pontine myelinolysis. ez2Find Home Directory Health http://ez2find.com/cgi-bin/directory/meta/search.pl/Health/Conditions_and_Diseas

Guide : Central Pontine Myelinolysis Global Metasearch Any Language English Afrikaans Arabic Bahasa Melayu Belarusian Bulgarian Catala Chinese Simplified Chinese Traditional Cymraeg Czech Dansk Deutsch Eesti Espanol Euskara Faroese Francais Frysk Galego Greek Hebrew Hrvatski Indonesia Islenska Italiano Japanese Korean Latvian Lietuviu Lingua Latina Magyar Netherlands Norsk Polska Portugues Romana Russian Shqip Slovensko Slovensky Srpski Suomi Svenska Thai Turkce Ukrainian Vietnamese Mode All Words Any Word Phrase Results Timeout Depth Adult Filter Add to Favorites Other Search Web News Newsgroups Images Invisible Web Metasearch Psych Central WebCam Central Home School Central Guides Central Pontine Myelinolysis ez2Find Home Directory Health Conditions and Diseases ... Metabolic : Central Pontine Myelinolysis Related Categories Health: Conditions and Diseases: Neurological Disorders: Demyelinating Diseases Web Sites Drkoop: Medical Encyclopedia: Central Pontine Myelinolysis [Site Info] [Translate] [Open New Window] A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. URL: http://www.drkoop.com/ency/article/000775.htm

37. Central Pontine Myelinolysis Directory, Home Health Conditions and Diseases Neurological Disorders Brain Diseases Metabolic central pontine myelinolysis (3) See Also http://www.thenewhealthfind.com/Health/ConditionsandDiseases/NeurologicalDisorde

Directory Home Health Conditions and Diseases Neurological Disorders ... Metabolic : Central Pontine Myelinolysis (3) See Also: Health: Conditions and Diseases: Neurological Disorders: Demyelinating Diseases Drkoop: Medical Encyclopedia - A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. E-Medicine - Central Pontine Myelinolysis: An introduction, clinical features, differencials, work up, treatment and follow up. Pediatric Database - A definition of central pontine myelinolysis, the epidemiology, pathogenesis, clinical features, investigations and management. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor Quick Links diabeties dental health accutane passing urine tests ... Mushroom Combination The New Health Directory Site Map Privacy Contact Advertise ... Health Directory

38. Help HER - Hyperemesis Education Research - Foundation » About Hyperemesis » C central pontine myelinolysis Nerve damage Encephalopathy. Home » About Hyperemesis » Complications » central pontine myelinolysis. Copyright http://www.hyperemesis.org/hyperemesis-gravidarum/complications/central-pontine.

Acute Renal Failure Atrophy Central Pontine Myelinolysis Coagulopathy ... About H.E.R. Central Pontine Myelinolysis Nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). For more info, see our Neurological Conditions page. Offsite Research: Magnetic resonance imaging detection of a lesion compatible with central pontine myelinolysis in a pregnant patient with recurrent vomiting and confusion. Valiulis B, Kelley RE, Hardjasudarma M, London S. Department of Psychiatry, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA Journal of Neuroimaging 2001 Oct;11(4):441-3. [Central pontine myelinolysis and pregnancy: a case report and review of literature] [Article in Spanish] Burneo J, Vizcarra D, Miranda H. Shriners Burns Institute, Galveston 77550, Texas, USA. Revista de neurologia 2000 Jun 1-15;30(11):1036-40. Related Links: Neurological Conditions Information about Central Pointine Myelinolysis and Wernicke's Encephalopathy. Home About Hyperemesis Complications Updated on: Apr. 03, 2004

39. Help HER - Hyperemesis Education Research - Foundation » Health Professionals  central pontine myelinolysis Nerve damage Encephalopathy. Home » Health Professionals » Complications » central pontine myelinolysis. Copyright http://www.hyperemesis.org/health-professionals/complications/central-pontine.ph

Acute Renal Failure Atrophy Central Pontine Myelinolysis Coagulopathy ... About H.E.R. Central Pontine Myelinolysis Nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). For more info, see our Neurological Conditions page. Offsite Research: Magnetic resonance imaging detection of a lesion compatible with central pontine myelinolysis in a pregnant patient with recurrent vomiting and confusion. Valiulis B, Kelley RE, Hardjasudarma M, London S. Department of Psychiatry, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA Journal of Neuroimaging 2001 Oct;11(4):441-3. [Central pontine myelinolysis and pregnancy: a case report and review of literature] [Article in Spanish] Burneo J, Vizcarra D, Miranda H. Shriners Burns Institute, Galveston 77550, Texas, USA. Revista de neurologia 2000 Jun 1-15;30(11):1036-40. Related Links: Neurological Conditions Information about Central Pointine Myelinolysis and Wernicke's Encephalopathy.

40. Central Pontine Myelinolysis central pontine myelinolysis. Alternative Names The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. http://lebonheur.adam.com/pages/content.asp?genId=000775&proj=1&lang=en

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