1. EMedicine - Central Pontine Myelinolysis : Article By Christopher C Luzzio, MD central pontine myelinolysis Adams et al described central pontine myelinolysis (CPM) as a unique clinical entity. central pontine myelinolysis. http://www.emedicine.com/neuro/topic50.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Neurotoxicology Central Pontine Myelinolysis Last Updated: March 12, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: osmotic myelinolysis AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Christopher C Luzzio, MD , Clinical Assistant Professor, Department of Neurology, University of Wisconsin at Madison Christopher C Luzzio, MD, is a member of the following medical societies: American Academy of Neurology Editor(s): Howard A Crystal, MD , Professor, Departments of Neurology and Pathology, State University of New York Downstate; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, Pharmacy, eMedicine; Richard J Caselli, MD , Chairperson, Department of Neurology, Professor, Department of Neurology, Mayo Clinic of Scottsdale; Selim R Benbadis, MD

2. Central Pontine Myelinolysis A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. http://www.drkoop.com/ency/article/000775.htm

Advertisement Search Dr. Koop Web MEDLINE Special Offers TV Specials Top Features Schizophrenia Hair Loss Liver Disease Allergies ... Impotence Resources Subscribe to our Free Newsletter Health Encyclopedia ... Privacy Policy Advertisement Advertisement Disease Injury Nutrition Poison ... Prevention Central pontine myelinolysis Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.

3. MedlinePlus Medical Encyclopedia: Central Pontine Myelinolysis central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of most common cause of central pontine myelinolysis is a rapid, drastic change http://www.nlm.nih.gov/medlineplus/ency/article/000775.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Central pontine myelinolysis Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Central nervous system Alternative names Return to top CPM Definition Return to top Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Causes, incidence, and risk factors Return to top The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.

4. Central Pontine Myelinolysis Was First Described By Adams Et Al... central pontine myelinolysis Following Hemodialysis. Author Dr R Dewan, Dr Rahul Rai, Dr Praveen Gupta, Dr Rahul Anand, Dr Pankaj Mehta, Dr Sameer Gulati http://www.indegene.com/Neu/ClinRound/indNeuCase10.html

Central Pontine Myelinolysis Following Hemodialysis Author: Dr R Dewan, Dr Rahul Rai, Dr Praveen Gupta, Dr Rahul Anand, Dr Pankaj Mehta, Dr Sameer Gulati Hospital: Depatment of Medicine, Maulana Azad Medical College, New Delhi Introduction Central pontine myelinolysis was first described by Adams et al in 1959 during the course of studying the neuropathology of alcoholism. The lesion was localized to the central rostral part of the pons and consisted of a sharply outlined focus of myelin destruction. Quadriplegia and pseudobulbar palsy were the main clinical findings. CPM was usually a postmortem diagnosis till the advent of the CT and the MRI. We report this interesting case of a young lady who developed CPM following hemodialysis. Case Report A young 26-year-old lady, a diagnosed case of Hypertension with MPGN with Chronic Renal Failure, was admitted with complaints of sudden onset loss of consciousness. The patient had developed altered sensorium 4 days before presentation, for which she was taken to a private nursing home and was hemodialysed twice. Following dialysis she developed drooping of the right eyelid and progressive paraparesis. Following this the patient developed loss of consciousness, when she was brought to our hospital. There was no other significant history. On examination the patient was unconscious, not responding to painful stimulus and a blood pressure of 180/130. The general physical examination showed pallor and facial puffiness but no icterus, clubbing or lymphadenopathy. Chest, CVS and per abdomen examination was normal. CNS examination revealed deep comatose state, a right third nerve palsy, paraparesis, which later progressed to quadriparesis, with bilateral up-going plantars.

5. Central Pontine Myelinolysis central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of most common cause of central pontine myelinolysis is a rapid, drastic change http://www.pennhealth.com/ency/article/000775.htm

Search Encyclopedia: List of Topics Print This Page  Cognitive Neurology Central pontine myelinolysis Central nervous system Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves. Risks include hyponatremia from any cause.

6. EMedicine - Central Pontine Myelinolysis : Article Excerpt By: Christopher C Luz central pontine myelinolysis Adams et al described central pontine myelinolysis (CPM) as a unique clinical entity. Excerpt from central pontine myelinolysis. http://www.emedicine.com/neuro/byname/central-pontine-myelinolysis.htm

(advertisement) Excerpt from Central Pontine Myelinolysis Synonyms, Key Words, and Related Terms: osmotic myelinolysis Please click here to view the full topic text: Central Pontine Myelinolysis Background: Adams et al described central pontine myelinolysis (CPM) as a unique clinical entity. They published their findings in 1958, observing that patients who suffered from alcoholism or malnutrition developed spastic quadriplegia, pseudobulbar palsy, and varying degrees of encephalopathy or coma from acute, noninflammatory demyelination that centered within the basis pontis. Contemporary physicians recognize that CPM occurs inconsistently as a complication of severe and prolonged hyponatremia, particularly when corrected too rapidly. Standard of care requires judicious treatment of electrolyte disturbances to reduce the incidence of osmotic myelinolysis. Pathophysiology: CPM is concentrated, frequently symmetric, noninflammatory demyelination within the central basis pontis. In at least 10% of patients with CPM, demyelination also occurs in extrapontine regions, including the mid brain, thalamus, basal nuclei, and cerebellum. The exact mechanism that strips the myelin sheath is unknown. One theory proposes that in regions of compact interdigitation of white and gray matter, cellular edema, which is caused by fluctuating osmotic forces, results in compression of fiber tracts and induces demyelination. Prolonged hyponatremia followed by rapid sodium correction results in edema. During the period of hyponatremia, the concentration of intracellular charged protein moieties is altered; reversal cannot parallel a rapid correction of electrolyte status. The term "osmotic myelinolysis" is more appropriate than "central pontine myelinolysis" for demyelination occurring in extrapontine regions after the correction of hyponatremia.

7. Pediatric Database A definition of central pontine myelinolysis, the epidemiology, pathogenesis, clinical features, investigations and management. http://www.icondata.com/health/pedbase/files/CENTRALP.HTM

8. Medical Encyclopedia: Central Pontine Myelinolysis (Print Version) Medical Encyclopedia central pontine myelinolysis. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. http://www.nlm.nih.gov/medlineplus/print/ency/article/000775.htm

To print this page, use the print option from your browser. To close this window, click on the "x" in the upper right hand corner of the window. Medical Encyclopedia: Central pontine myelinolysis URL of this page: http://www.nlm.nih.gov/medlineplus/ency/article/000775.htm Alternative names CPM Definition Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). Causes, incidence, and risk factors The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium (hyponatremia) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.

9. NeuroGate.com Search results for "central pontine myelinolysis" Cardioguide Matches 1 1 of 1. demyelinating disease - http://www.neurogate.com/neuro/result.php3?search=Central Pontine Myelinolysis&a

10. Central Pontine Myelinolysis central pontine myelinolysis. Alternative Names CPM. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. http://www.drkoop.com/ency/article/000775trt.htm

Advertisement Search Dr. Koop Web MEDLINE Special Offers TV Specials Top Features Schizophrenia Hair Loss Liver Disease Allergies ... Impotence Resources Subscribe to our Free Newsletter Health Encyclopedia ... Privacy Policy Advertisement Advertisement Disease Injury Nutrition Poison ... Prevention Central pontine myelinolysis Alternative Names: CPM Treatment: This is an emergency disorder that requires hospitalization for initial diagnosis and treatment. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. Double vision may be reduced with the use of an eye patch. Physical therapy may help maintain muscle strength, mobility and function in weakened arms and legs. Expectations (prognosis): The neurologic damage caused by central pontine myelinolysis is usually persistent. The disorder can cause serious chronic disability. Complications: Permanent neurologic losses Decreased ability to work or care for self Decreased ability to interact with others Calling your health care provider: Go to the emergency room or call the local emergency number (such as 911) if seizures muscle weakness , or other symptoms of central pontine myelinolysis occur.

11. Myelinolysis, Central Pontine Myelinolysis, Central Pontine Medical.WebEnds.com Myelinolysis, Central Pontine. central pontine myelinolysis; Extrapontine Myelinolysis; Extrapontine Central Pontine; Pontine Myelinolysis http://medical.webends.com/index.php?id=15150

12. Central Pontine Myelinolysis - Information / Diagnosis / Treatment / Prevention home neurological disorders brain diseases metabolic central pontine myelinolysis central pontine myelinolysis. Information http://www.healthcyclopedia.com/neurological-disorders/brain-diseases/metabolic/

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... metabolic > central pontine myelinolysis Central Pontine Myelinolysis Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Related Topics Medical Definition Health News Web Directory: Related Topics: Neurological Disorders/Demyelinating Diseases Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "central pontine myelinolysis" Health News: Search millions of published articles for news on Central Pontine Myelinolysis Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Drkoop: Medical Encyclopedia: Central Pontine Myelinolysis A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. E-Medicine Central Pontine Myelinolysis: An introduction, clinical features, differencials, work up, treatment and follow up.

13. Central Pontine Myelinolysis Medical Encyclopdia article about central pontine myelinolysis central pontine myelinolysis. A Medical Encyclopedia Article provided by the University of with information on over 4000 medical http://www.umm.edu/medical-terms/02060.htm

Central pontine myelinolysis A Medical Encyclopedia Article provided by the University of Maryland Medical System A resource with information on over 4000 medical topics including: Central pontine myelinolysis Previous Next

14. Central Pontine Myelinolysis Following Hemodialysis - Images Top. Email this Article to a Colleague, Search, Participate in Discussions. Members Agreement, Privacy Policy, Disclaimer, Copyright 2000 of Indegene Lifesystems Pvt. http://www.indegene.com/Neu/ClinRound/indNeuCase10child.html

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15. Central Pontine Myelinolysis central pontine myelinolysis. toxic demyelination. rapid correction of hyponatremia. low density in central pons. variable size. may have paired, rounded lesions http://chorus.rad.mcw.edu/to-go/00066.html

central pontine myelinolysis toxic demyelination rapid correction of hyponatremia low density in central pons variable size may have paired, rounded lesions enhances in acute phase See also: demyelinating diseases white-matter diseases Home Nervous system

16. AllRefer Health - Central Pontine Myelinolysis (CPM) central pontine myelinolysis (CPM) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, tests, support http://health.allrefer.com/health/central-pontine-myelinolysis-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Central Pontine Myelinolysis Central Pontine Myelinolysis Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : CPM Definition Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Central Nervous System The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly.

17. AllRefer Health - Central Pontine Myelinolysis Prognosis (Expectations) (CPM) central pontine myelinolysis (CPM) information center covers Prognosis (Expectations). Myelinolysis. central pontine myelinolysis. http://health.allrefer.com/health/central-pontine-myelinolysis-prognosis.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Central Pontine Myelinolysis : Prognosis of Central Pontine Myelinolysis Central Pontine Myelinolysis Definition Prevention Treatment Expectations or Prognosis Complications Calling Your Health Care Provider Go To Main Page Alternate Names : CPM Prognosis (Expectations) The neurologic damage caused by central pontine myelinolysis is usually persistent. The disorder can cause serious chronic disability. Previous Top Next Jump to another section Definition Prevention Treatment Prognosis Complications Calling Your Health Care Provider Topics that might be of interest to you Alcoholism Cranial Mononeuropathy VI Delirium Dilutional Hyponatremia (SIADH) ... Nerve Conduction Velocity Other Topics Chronic Confusion Consciousness - Decreased Constipation ... Weakness Review Date : 7/28/2002 Reviewed By : Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

18. HealthCentral - General Encyclopedia - Central Pontine Myelinolysis central pontine myelinolysis. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. http://www.healthcentral.com/mhc/top/000775.cfm

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19. Metabolic Disorders: Central Pontine Myelinolysis, Marchiafava-Bignami Disease central pontine myelinolysis. Case 1, Related Internet Resources. central pontine myelinolysis, eMedicine; Demyelinating Diseases Internet Handbook of Neurology; http://www.neuropat.dote.hu/alcoh.htm

Metabolic Disorders Marchiafava-Bignami disease Case 1 Case 2 Related Internet Resources MRI Images - University of Florida, US Central pontine myelinolysis Case 1 Related Internet Resources Myelinolysis after Correction of Hyponatremia, Annals of Internal Medicine, 1997, 126:57-62 Other Resources Central Pontine Myelinolysis, eMedicine Demyelinating Diseases - Internet Handbook of Neurology Toxic Disorders - Internet Handbook of Neurology var site="sm5hegeduskdote" Last modified: February 17, 2001 If you have any comments, please, contact Neuroanatomy Structures Online Neuropathology Atlas Internet Handbook of Neurology

20. Demyelinating Diseases - Internet Handbook Of Neurology demyelinating diseases, multiple sclerosis, leukodystrophy, central pontine myelinolysis, progressive multifocal leukoencephalopathy. http://www.neuropat.dote.hu/myelin.htm

Internet Handbook of Neurology Compiled by K atalin H Department of Neurology University of Debrecen, Hungary Demyelinating Diseases Chapters: A Collection of High Quality Online Resources for Health Professionals Pathology see Pathology of Infectious Diseases and Disease of Myelin Overview - Washington University Disorders of Myelination - University of Berkeley Demyelinating Diseases of the Brain - University of California, San Diego Diseases of Myelin - University of New Mexico Chemokine Regulation of Immune-mediated Demyelinating Disease - ILAR Journal, Vol 40(4) 1999 Pathology of Inflammatory Demyelinating Diseases - Mayo Clinic Viral Induced Demyelination - Brain Pathology, January 2001 (PDF) Is There a Role for Human Herpesvirus-6 in the Course of Multiple Sclerosis? - International Journal of MS Care, March Multiple Sclerosis Overview Multiple Sclerosis - Neurology Associates of Arlington Multiple Sclerosis - Praxis MD Multiple Sclerosis: Current Status and Strategies for the Future - National Academy Press, Multiple Sclerosis: Lectures - University of Utah, Houston (

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