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         Autonomic Dysreflexia:     more detail
  1. Autonomic Dysreflexia: What You Should Know- Consumer Guide
  2. Neurologic Emergencies with CDROM

61. Health, Conditions And Diseases, Neurological Disorders, Autonomic Nervous Syste
Injury. AD Fact Sheet An article explaining what autonomic dysreflexiais and how it occurs. RehabNET Monographs - A description
http://www.combose.com/Health/Conditions_and_Diseases/Neurological_Disorders/Aut
Top Health Conditions and Diseases Neurological Disorders ... Autonomic Dysreflexia
Related links of interest: A syndrome associated with damage to the spinal cord above the mid thoracic level characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor The combose.com directory is based on the Open Directory and has been modified and enhanced using our own technology. About ComboSE Download Combose Toolbar

62. Autonomic Dysreflexia
autonomic dysreflexia. If your injury is above T8, you are at riskfor developing autonomic dysreflexia. It is caused by an annoying
http://www.physicaltherapy.ca/neuro/sci-autodys.html
Autonomic Dysreflexia
If your injury is above T8, you are at risk for developing autonomic dysreflexia. It is caused by an annoying stimulus below the level of the lesion and causes an increase in your blood pressure. This increase in blood pressure can cause dizziness, severe headaches, sweating, goose bumps, blurred vision, and a sick feeling. It is a medical emergency!
Examples of annoying stimuli that can cause autonomic dysreflexia are pressure sores, a full bladder, or temperature changes.

63. Autonomic Dysreflexia
EDUBRIEFS in CCTC autonomic dysreflexia What is it? A lifethreateningsyndrome that can occur in individuals with cord injuries
http://www.lhsc.on.ca/critcare/icu/education/dysreflex.html
EDUBRIEFS in CCTC
Autonomic Dysreflexia

What is it?
  • A life-threatening syndrome that can occur in individuals with cord injuries above T6 (most common in quadriplegia). Autonomic dysreflexia is a pathologic response to pain or other noxious stimuli, and is characterized by hypertension, bradycardia and vasodilation above the level of the cord injury. Can develop any time after the period of spinal shock ends.
Pathophysiology
  • Distention or contraction of the bladder or bowel, or stimulation of skin or pain receptors triggers a sympathetic response (from intact autonomic reflex arc) below the level of the lesion. The release of catecholamines causes vasoconstriction and hypertension. Hypertension stimulates baroreceptors in the carotid sinus, aorta and cerebral vessels. This causes the parasympathetic nervous system to be stimulated, which attempts to restore the BP back to normal. The heart rate decreases (vagal nerve), but inhibitory messages are unable to relax the blood vessels below the cord lesion. Vasoconstriction below the level of the cord injury causes the hypertension to persist.

64. Autonomic Dysreflexia
Care must be taken to ensure that catheterization frequency is sufficient to preventbladder distention, as a full bladder can trigger autonomic dysreflexia.
http://www.lhsc.on.ca/critcare/icu/education/bladder.html
EDUBRIEFS in CCTC
Maintaining Bladder Function in Spinal Cord Injury

Bladder Drainage in Spinal Cord Injury
  • In spinal cord injury, bladder sphincter relaxation is absent, leading to urinary retention. As soon as hourly urine output is no longer necessary, the indwelling bladder catheter should be removed to reduce the risk of urinary tract infections (a life-threatening complication of acute spinal cord injury). Intermittent catheterization decreases the risk for urinary tract infections.
Considerations
  • Immediately following acute spinal cord injury, spinal shock develops. Spinal shock is characterized

  • by flaccid paralysis (loss of bladder tone) below the level of the injury, and loss of spinal cord
    reflexes including bladder and bowel sphincter control. Spinal shock often coincides with
    neurogenic shock, which is evidenced by loss of autonomic control (bradycardia, vasodilation,
    hypotension). Spinal shock can persist for several weeks, and is associated with an inability to
    retain urine or bowel contents. Although urinary incontinence may be present, bladder emptying is
    also dysfunctional, making some form of catheterization mandatory.

65. :: Ez2Find :: Autonomic Dysreflexia
Guide autonomic dysreflexia, Global Metasearch Any Language Guides, AutonomicDysreflexia. ez2Find Home Directory Health Conditions
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Guide : Autonomic Dysreflexia Global Metasearch
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66. Untitled Document
autonomic dysreflexia. autonomic dysreflexia (AD) is a lifethreateningcondition that can occur in persons with spinal cord injury.
http://www.rnceus.com/uro/ad.htm
Autonomic Dysreflexia Autonomic Dysreflexia (AD) is a life-threatening condition that can occur in persons with spinal cord injury. AD is an acute episode of exaggerated sympathetic reflex response It occurs because SCI disrupts feedback mechanisms to the cord below the injury. Without inhibitory feedback, afferent stimuli travel uninhibited between reflex centers. It is usually brought on by visceral stimuli that normally cause pain or discomfort in the abdominal or pelvic region. It is uncommon for AD to occur until spinal shock has resolved, usually about 6 months after injury. It is most unpredictable during the first year following injury, but can occur throughout the person's lifetime. AD is usually characterized by hypertension ranging from mild (20 mm hg above baseline) to severe hypertension as high as 300/160, bradycardia and headache ranging from dull to severe and pounding. Instant Feedback: AD most often occurs within the first 6 months after injury.
True
False
AD is associated with injuries at T6 and above. An injury below T6, usually allows sufficient cerebral vasomotor inhibition to control sympathetic reflexes. The inverse is true for injuries at or above T6, uninhibited sympathetic release of norepinephrine and dopamine below the level of injury causes vasospasm, hypertension, skin pallor and gooseflesh associated with the piloerector response. At the same time, baroreceptor function and parasympathetic control of heart rate remain intact. Continued hypertension produces a baroreflex-mediated vagal slowing of heart rate to bradycardic levels. Accompanying that is a baroreflex-mediated vasodilatation, causing the flushed skin and profuse sweating above the level of injury, along with sudden onset of a pounding headache, nasal stuffiness and feelings of anxiety.

67. Conditions And Diseases - Autonomic Dysreflexia Top Links
autonomic dysreflexia Web Site Links. AD Fact Sheet An article explainingwhat autonomic dysreflexia is and how it occurs. Paralyzed
http://www.disease-resources.com/Top_Health_Conditions_and_Diseases_Neurological
Sub Categories
Related Healthcare Subjects Disabilities Environmental Health Fitness Health Insurance ... Men's Health
Autonomic Dysreflexia Web Site Links AD Fact Sheet An article explaining what autonomic dysreflexia is and how it occurs.
Paralyzed Veterans of America
A consumer guide to autonomic dysreflexia, what should be known. For down load on PDF.
RehabNET Monographs
A description of Autonomic dysreflexia, including the signs and symptoms, the causes, management and prevention.
Spinal Cord Injury Information
Details about autonomic dysreflexia, the symptoms and why they happen and finding and removing the causes.
Other Useful Health Web Links National Institutes of Health (NIH) US Government department in charge of medical research.
AHRQ: Clinical Information
Clinical information on evidence-based practice, clinical guidelines, medical effectiveness, pharmaceutical therapy, new technology, screening and preventive services, outcomes research, and the National Guideline Clearinghouse.
The UK Health Technology Assessment Programme
Site contains details of program's many projects and publications; an NHS national research and development initiative.
U.S. Preventive Services Task Force (USPSTF)

68. Autonomic Hyperreflexia
Images (Click to view larger image) Autonomic nervous system Alternative Namesautonomic dysreflexia, dysreflexia, hyperreflexia Definition Autonomic
http://www.northmemorial.com/healthencyclopedia/content/538.asp
autonomic hyperreflexia
Images
(Click to view larger image)
Alternative Names
autonomic dysreflexia, dysreflexia, hyperreflexia
Definition
Autonomic hyperreflexia is an abnormal triggering of the autonomic nervous system. It occurs after a spinal cord injury . The body is unable to turn off the nerves that cause blood pressure to rise.
What is going on in the body?
Normally, the autonomic nervous system controls blood pressure automatically. It does this by commanding muscles around blood vessels to tighten or relax in order to raise or lower blood pressure. The nervous system can monitor blood pressure and continually adjusts the commands to keep blood pressure normal.
When a person has a spinal cord injury , it can cause damage to nerves in the spinal cord. And this results in a loss of control in the nerves. This can happen if the damage to the spinal cord is in the neck or upper back. The bones of the spine are each labeled and numbered. Damage at the 6th thoracic bone or higher means the person may develop this problem. If the damage is lower, autonomic hyperreflexia will not be a problem.
In autonomic hyperreflexia, the autonomic nervous system can still cause the blood pressure to rise. But it cannot easily cause it to come back down.

69. Alexa Web Search - Subjects > Health > ... > Neurological Disorders > Autonomic
autonomic dysreflexia Subjects Health Neurological Disorders Autonomic Nervous System autonomic dysreflexia. Sort by
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70. Health - Conditions And Diseases - Neurological Disorders
Info. Search Top Health Conditions and Diseases NeurologicalDisorders Autonomic Nervous System autonomic dysreflexia See
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Web Hosting Dir Web Design Dir Search Engine Dir Hardware Info ... Resources Search: Top Health Conditions and Diseases Neurological Disorders ... Autonomic Dysreflexia See also:

71. Paraplegia News : Autonomic Dysreflexia. (autonomic Hyperreflexia) @ HighBeam Re
Paraplegia News autonomic dysreflexia. (autonomic hyperreflexia) @ HighBeamResearch. Read Paraplegia News autonomic dysreflexia.
http://static.highbeam.com/p/paraplegianews/april011997/autonomicdysreflexiaauto
Tour Become a Member ... Customer Support Question / Keyword(s): Advanced Search
  • Current Article: Autonomic dysreflexia. (autonomic hyperreflexia)
Start P Paraplegia News April 01, 1997 ... Autonomic dysreflexia. (autonomic hyperreflexia)
Autonomic dysreflexia. (autonomic hyperreflexia)
Paraplegia News; April 01, 1997; Chanaud, Cheryl M.
Chanaud, Cheryl M.
Paraplegia News
April 01, 1997
blood pressure, blood vessels, ad, sci, spinal cord, autonomic dysreflexia, side effects, brain, urinary tract, ad symptoms, ad episodes, heart rate, animal models, injury, people
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72. Transverse Myelitis Internet Club List: Autonomic Dysreflexia
autonomic dysreflexia. James Lubin (jlubin(AT)eskimo.com) Sat, 05 Apr1997 192723 0800 autonomic dysreflexia. autonomic dysreflexia
http://www.myelitis.org/tmic/archive/6/0143.html
Autonomic Dysreflexia
James Lubin (
Sat, 05 Apr 1997 19:27:23 -0800 Autonomic Dysreflexia
Autonomic dysreflexia (AD) is a condition that can occur in anyone who has
a spinal cord injury at or above the T6 level. It is related to
disconnections between the body below the injury and the control mechanisms
for blood pressure and heart function. It causes the blood pressure to rise
to potentially dangerous levels.
AD can be caused by a number of things. The most common causes are a full
bladder, bladder infection, severe constipation, or pressure sores.
Anything that would normally cause pain or discomfort below the level of
the spinal cord injury can trigger dysreflexia. AD can occur during medical tests or procedures and need to be watched for. The symptoms that occur with AD are directly related to the types of responses that happen in the sympathetic and parasympathetic nervous systems. Symptoms such as a pounding headache, spots before the eyes, or

73. AUTONOMIC DYSREFLEXIA
ISIC FAQs top. What is autonomic dysreflexia? Only if you have a spinal cord lesionabove T6 are you prone to autonomic dysreflexia or hyper-reflexia.
http://www.websters-online-dictionary.org/definition/english/Au/Autonomic Dysref
Philip M. Parker, INSEAD.
AUTONOMIC DYSREFLEXIA
Specialty Definition: AUTONOMIC DYSREFLEXIA
Domain Definition
Health
That part of the nervous system concerned with the unconscious regulation of the living processes of the body. ( references Source: compiled by the editor from various references ; see credits. Top
Non-Fiction Usage: AUTONOMIC DYSREFLEXIA
Subject Topic Quote
Health
Spinal cord injuries can lead to many secondary complications, including pressure sores, increased susceptibility to respiratory diseases, and autonomic dysreflexia references Autonomic dysreflexia is a potentially life-threatening increase in blood pressure, sweating, and other autonomic reflexes in reaction to bowel impaction or some other stimulus. ( references Source: compiled by the editor from ICON Group International, Inc. ; see credits. Top
Frequency of Internet Keywords: AUTONOMIC DYSREFLEXIA
The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com

74. Autonomic Dysreflexia : On Medical Dictionary Online
autonomic dysreflexia defined on the Free Online Medical Dictionary. Medicalterminology definitions autonomic dysreflexia. A syndrome associated
http://www.online-medical-dictionary.org/?q=Autonomic Dysreflexia

75. ScienceDaily -- Browse Topics: Health/Conditions_and_Diseases/Neurological_Disor
News about autonomic dysreflexia Vanderbilt full story. More newsabout autonomic dysreflexia . Books about autonomic dysreflexia 1
http://www.sciencedaily.com/directory/Health/Conditions_and_Diseases/Neurologica
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Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Autonomic Nervous System Autonomic Dysreflexia (3 links) See Also: News about Autonomic Dysreflexia Vanderbilt Study Shows Cold Drug Ingredient Could Cause Strokes (April 20, 2004) full story Unsuspected Brain Region Involved In Side Effects Of Diabetes Drugs (March 17, 2004) full story USC Study Finds Faulty Wiring In Psychopaths (March 11, 2004) full story OHSU Team Discovers Compound That Lacks Estrogen's Risks (December 31, 2003) full story Shyness Can Be Deadly (December 17, 2003)

76. Spinal Research
Mechanisms of autonomic dysreflexia following spinal cord injury. AG Rabchevsky.GM Smith. Categories autonomic dysreflexia. Chronic (late). Growth factors.
http://www.spinal-research.org/display_page.asp?section=database&id=71

77. EMedHome.com Archives Of Featured Articles, Clinical Cases, Clinical Pearls, And
autonomic dysreflexia autonomic dysreflexia (autonomic hyperreflexia) is apotentially fatal emergency unique to the spinal cord injured patient.
http://www.emedhome.com/features_archive-detail.cfm?FID=282

78. Home
3. autonomic dysreflexia. autonomic dysreflexia is a serious consequenceof SCI for some patients with higher (above T6) injuries.
http://www.spinal.co.uk/help/bladder/page 7.html
Page: 7
There are a variety of effects that can result from changes in bladder behaviour following SCI. These side effects can include the following: 1. Incomplete bladder emptying and urinary infection Before a SCI people are usually able to completely empty the bladder each time they pass water. This is one of the most important defences against urinary infection. In any situation in which the bladder does not fully empty there is an increased risk of urinary infection from bacteria growing in the urine. Both reflex and flaccid bladders after SCI may not empty fully. Urinary Tract Infection (UTI) may result which as well as causing unpleasant symptoms (such as fever and sickness), can also result in kidney damage. 2. Incontinence of urine Following SCI normal control of urination will be lost. If the bladder develops a reflex pattern it may empty spontaneously without any conscious control. Even with a flaccid bladder incontinence can occur - either because of overflow (continuous dribbling because the bladder is so full) or as a result of a co-existing weakness of the sphincter, this is called stress incontinence. Not only is incontinence unpleasant and sometimes distressing, it can also contribute to skin problems and pressure sore development. By finding information that is relevant to you in this document and perhaps by requesting additional advice, you will be able to address incontinence and prevent it disrupting your life disproportionately.

79. Welcome To The Spinal Injuries Association
Supported by Astra Tech Ltd makers of the LoFricĀ® catheter. autonomic dysreflexiaAuthor, Message. Posted 8/28/2003 ` autonomic dysreflexia ?
http://www.spinal.co.uk/messageboard/default.asp?step=3&id=842&f=12

80. Autonomic Dysreflexia In A Rat Model Spinal Cord Injury And The Effect Of Pharma
autonomic dysreflexia in a rat model spinal cord injury and the effect ofpharmacologic agents. Rivas DA, Chancellor MB, Huang B, Salzman SK.
http://wellstreetpharmacy.com/ref-ditropan/ditropan-research-abs3.41.html
Ditropan_XL References
Neurourol Urodyn. 1995;14(2):141-52.
Autonomic dysreflexia in a rat model spinal cord injury and the effect of pharmacologic agents.
Rivas DA, Chancellor MB, Huang B, Salzman SK.

Department of Urology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Res Commun Mol Pathol Pharmacol. 1994 Sep;85(3):303-12.
Histological study of the parotid gland in rats treated with oxybutynin hydrochloride.
Saito M, Yamada A, Miyazaki Y, Sakurada T, Kisara K.

Department of Dentistry, Shizugawa Public General Hospital, Miyagi, Japan.
The purpose of this study was to determine whether oxybutynin hydrochloride (OBHC) induces histological changes in the parotid gland. Thirty male rats were divided into three groups, young (8 weeks), middle-aged (20 weeks) and old (113 weeks). Six rats in each group were given a diet containing OBHC mixed with the standard food. Four rats in each group had free access to standard food as a control. Eight weeks after dieting, all animals were sacrificed and removed their parotid gland. Degeneration, dispersion of basophilic material and transformation of nuclear shape in the acinar cells and atrophy of duct cells were observed in 5 young, 2 middle aged and 6 old rats. There were no appreciable histological changes in young and middle-aged control rats, although an aged-related effect of OBHC was seen in older control animals. These results indicate that chronic treatment with OBHC produces significant effects of aging on histological changes in the parotid gland of rats.

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