41. Antiphospholipid Syndrome Articles, Support Groups, And Resources antiphospholipid syndrome articles, support groups, and resources for patients from Med Help International (www.medhelp.org). antiphospholipid syndrome. http://www.medhelp.org/HealthTopics/Antiphospholipid_Syndrome.html

[Health Topics A-Z] A B C D ... Z Antiphospholipid Syndrome Medical Glossary: ANTIPHOSPHOLIPID SYNDROME Ask The Doctor Forums Antiphospholipid Syndrome and Chronic Headache (Neurology and Neurosurgery Forum) [Med Help Home] [Library Search] [Medical Forums] ... [Patient Network] Revised: 5/30/2004

42. ANTIPHOSPHOLIPID SYNDROME antiphospholipid syndrome An uncommon disorder that is characterized by hypercoagulability due to the presence of antibodies against phospholipids These http://www.medhelp.org/glossary2/new/GLS_0436.HTM

ANTIPHOSPHOLIPID SYNDROME - An uncommon disorder that is characterized by hypercoagulability due to the presence of antibodies against phospholipids These patients exhibit a tendency for recurrent and life-threatening thrombosis and embolic events (e.g. stroke ). Individuals with antiphospholipid syndrome or APS, also have an increased tendency toward deep venous thrombosis myocardial infarction and spontaneous abortions in females. APS may be seen by itself or in association with other autoimmune illnesses (e.g. lupus ) or with some infections . Treatment includes long-term heparin and warfarin. Med Help Home Search Ask the Doctor Patient Network The medical glossary has been made possible by a generous donation from:

43. ECMAJ -- Hanly 168 (13): 1675 licensors Review Synthèse. antiphospholipid syndrome an overview. John G. Hanly 80 , 81. Catastrophic antiphospholipid syndrome. Although http://www.cmaj.ca/cgi/content/full/168/13/1675

HOME HELP FEEDBACK SUBSCRIPTIONS ... COLLECTIONS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: PDF Version of this Article Email this article to a friend eLetters: Submit a response to this article Similar articles found in: eCMAJ PubMed PubMed Citation - Citation PubMed A correction has been published for this Article Search Medline for articles by - Chercher dans Medline des articles de: Hanly, J. G. Alert me when - Veuillez m'avertir si: new articles cite this article - de nouveaux articles citent cet article Download to Citation Manager Collections under which this article appears Other immunology Canadian Medical Association or its licensors Review Antiphospholipid syndrome: an overview John G. Hanly Dr. Hanly is Professor and Head of the Division of Rheumatology, Department of Medicine, and Director of the Arthritis Centre of Nova Scotia, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS. Correspondence to: Dr. John G. Hanly, Division of Rheumatology, Department of Medicine, QE II Health Sciences Centre, Suite 245, NSRC, 1341 Summer St., Halifax NS B3H 4K4; fax 902 473 7019; john.hanly@cdha.nshealth.ca

44. University Of Miami School Of Medicine - Glossary - Antiphospholipid Syndrome antiphospholipid syndrome. What is the antiphospholipid syndrome? antiphospholipid syndrome is also called the phospholipid antibody syndrome. http://www.med.miami.edu/patients/glossary/art.asp?articlekey=277

45. MSN Encarta - Dictionary - Antiphospholipid Syndrome antiphonary. antiphony. antiphospholipid syndrome. antiphrasis. antiplaque. Download the MSN Encarta RightClick Dictionary. antiphospholipid syndrome. Dictionary, http://encarta.msn.com/dictionary_561536654/antiphospholipid_syndrome.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... > > Click here to search all of MSN Encarta Dictionary Find in Click here to search all of MSN Encarta Translations antiperiodic antiperistalsis antipersonnel ... Print Preview Search for " antiphos... " in all of MSN Encarta Download the MSN Encarta Right-Click Dictionary antiphospholipid syndrome Dictionary an·ti·phos·pho·lip·id syn·drome noun medicine See Hughes’ syndrome Thesaurus * No thesaurus result for "antiphospholipid syndrome" > Translations for antiphospholi... Exclusively for MSN Encarta Premium Subscribers ... Newsletter Advertisement MSN Encarta Premium Our Partners Capella University: Online degrees ClassesUSA.com: Lifelong learning CollegeBound Network: ReadySetGo LearnitToday: Computer courses ... Kaplan Test Prep and Admissions Get Encarta 2004 "Nobody does it better..." Michael Sweet, Smart Computing in Plain English Check out Encarta 2004 Also on Encarta Have sports records become unbreakable? Compare top online degrees Democrats vs. Republicans: What's the difference? Also on MSN Outdoor BBQ: Everything you need Quest for Columbus on Discovery Channel Switch to MSN in 3 easy steps MSN Shopping From $14.99

46. The Spectrum Of The Antiphospholipid Syndrome: A Matter Of Perspective For many years, rheumatologists diagnosed what is now known as antiphospholipid syndrome (APS) as systemic lupus erythematosus (SLE). Search the Journal. http://www.jrheum.com/subscribers/01/09/1939.html

Search the Journal Home Current Issue Archives Guidelines for Authors ... Contact Info Editorial The Spectrum of the Antiphospholipid Syndrome: A Matter of Perspective For many years, rheumatologists diagnosed what is now known as antiphospholipid syndrome (APS) as systemic lupus erythematosus (SLE). We knew that many of these patients would never manifest other features of SLE but rather demonstrate only thrombosis, thrombocytopenia, or pregnancy loss. As a matter of fact, one or more of those manifestations was likely the reason the patient came to our attention in the first place. , we have come to appreciate that these patients do not have lupus but rather a separate but related entity, the APS. Although many of us have become complacent with this classification , we may still be unclear in many circumstances which patients to treat, when to treat, and how to treat. . When these laboratory markers are determined in a clinically inappropriate situation, the physician is left in a potential quandary: should this asymptomatic patient be treated or is it safe to ignore these laboratory abnormalities? . In either case, the hematologist sees a patient at risk for recurrent thrombotic events when confronted with APS.

47. Antiphospholipid Syndrome antiphospholipid syndrome. antiphospholipid syndrome is a disorder of coagulation, and causes thrombosis in both arteries and veins. http://www.fact-index.com/a/an/antiphospholipid_syndrome.html

Main Page See live article Alphabetical index Antiphospholipid syndrome Antiphospholipid syndrome is a disorder of coagulation , and causes thrombosis in both arteries and veins. It is an autoimmune disease , in which antibodies react against anionic phospholipids on ? cell membranes. People with this disease also are thrombocytopenic (low platelet number). It has an association with systemic lupus erythematosus (SLE), many people with antiphospholipid syndrome will go on to develop SLE. Being an autoimmune disease, it is more common in women than in men. This disease is often picked up in women by noticing recurrent miscarriages, (usually terminating in the second trimester Antiphospholipid syndrome is tested for in the laboratory by two tests. The person will have a prolonged APTT, that will not be corrected with a 50:50 mixture with normal plasma. This result is known as lupus anticoagulant . As well this, there is an immunological test which detects if there are antibodies in the plasma that react with cardiolipin. This disease is treated by giving aspirin to inhibit platelet activation, and

48. Antiphospholipid Syndrome (Hughes' Syndrome) APS Thromboses Acupuncture And Chin antiphospholipid syndrome (Hughes syndrome) Acupuncture and APS thromboses antiphospholipid syndrome chinese Herbal Medicine Centre body s immune system http://www.geocities.com/mastertole/Hughes.html

The Tole Institute of Acupuncture and Herbal Medicine Our New Medical Centre and Institute is offiacially opended by our Health Minister in 1993, January 31th. Y.A.B Dato. Lee Kim Sai. Antiphospholipid syndrome (Hughes' syndrome) Antiphospholipid syndrome (APS) is sometimes called 'sticky blood syndrome'. This is because people with it have an increased tendency to form clots in blood vessels (also known as thromboses). Any blood vessel can be affected including the veins, which are thin walled and take blood towards the heart, and the arteries, which have thick muscular walls, and take blood away from the heart. As a result of this clotting tendency these patients may develop repeated clots, eg in the veins of the leg (deep vein thrombosis), or in the arteries supplying the brain, causing a stroke. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy. Causes The 'antiphospholipid antibodies'. Antibodies are produced by the body's immune system to fight infection from bacteria and viruses. In some diseases, the immune system produces antibodies that mistakenly attack the body's own tissues. The result is an autoimmune disease, eg antiphospholipid syndrome. Phospholipids are phosphorus-containing fat molecules found throughout the body, particularly in the surrounding coat of cells - the cell membranes. The 'antiphospholipid antibodies' target the body's own phospholipids, and also proteins that bind to phospholipids.

49. SupportPath.com: Antiphospholipid Syndrome SupportPath.com, antiphospholipid syndrome. Also called Hughes Syndrome. None Listed. Clinical Trials Research on antiphospholipid syndrome http://www.supportpath.com/sl_a/antiphospholipid_syndrome.htm

Antiphospholipid Syndrome Also called: Hughes Syndrome About Us Add-A-Link Email Gallery ... here Online Communities / Message Boards... None Listed Online Chats... Note: Regularly scheduled chats are listed on our NEW Online Events Calendar Links in this section are primarily to chat rooms open 24/7 which may or may not be moderated. None Listed Usenet Groups... Note: Your browser must be properly configured to access Usenet groups from this site. None Listed Mailing Lists... None Listed National / International Organizations... UNITED KINGDOM Hughes Syndrome Foundation Website: http://www.hughes-syndrome.org/ Description: The aims of this registered charity: To offer understanding and support to sufferers of Hughes Syndrome; To offer information and education on Hughes Syndrome; To support research into the condition; To raise funds to provide information, education and research. Website includes information about Hughes Syndrome (Antiphospholipid Syndrome), research, and information on support groups. Date Added: 08/08/2002 Note: Groups are listed alphabetically by U.S. state and then country.

50. Antiphospholipid Syndrome Profile antiphospholipid syndrome Profile. Number. 250555. CPT. 85613; 85732; 86147 (x2). Test Includes. Anticardiolipin antibodies, IgG, quantitative http://www.labcorp.com/datasets/labcorp/html/chapter/mono/se032300.htm

Antiphospholipid Syndrome Profile Number CPT Test Includes Anticardiolipin antibodies, IgG, quantitative; anticardiolipin antibodies, IgM, quantitative; lupus anticoagulant Specimen Serum and frozen plasma Volume 1 mL serum and one plasma tube Container Red-stopper tube or serum-separator tube and blue-stopper (sodium citrate plasma) tube Collection When specimen is collected for multiple tests, the order of draw is 1) sterile culture tubes, 2) nonadditive (red-stopper) tubes, 3) coagulation (sodium citrate [blue-stopper] tubes), 4) serum-separator tubes, and 5) other additive (EDTA [lavender-stopper], heparin [green-stopper], etc) tubes. If only coagulation tests are being drawn, draw 5 mL into another tube, discard, and then collect coagulation tests. This collection procedure eliminates contamination of the specimen with tissue thromboplastins and cross-contamination from additives such as heparin and EDTA. Collect nine parts whole blood to one part 3.2% sodium citrate using plastic collection material, or draw one blue-stopper (sodium citrate) tube until the vacuum is depleted to ensure a 9:1 ratio. Centrifuge immediately at 3500 rpm for 15 minutes. Carefully remove the plasma, aliquot 2 mL of plasma into a plastic transport tube, and freeze immediately. If hematocrit (Hct) is >55%, use the following formula to calculate the volume of anticoagulant required for 5 mL of anticoagulated blood: X = (100-Hct) / (595-Hct). X is the volume of anticoagulant required to prepare unit volume of anticoagulated blood. Carefully remove the plasma from cells without disturbing the cells. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

51. Antiphospholipid Syndrome to be part of the clinical spectrum of SLE but while the 2 syndromes often coexist, SLE is not necessary for the diagnosis of antiphospholipid syndrome. http://www.aic.cuhk.edu.hk/web8/anti-phospholipid syndrome.htm

Anti-phospholipid syndrome Used to be considered to be part of the clinical spectrum of SLE but while the 2 syndromes often co-exist, SLE is not necessary for the diagnosis of antiphospholipid syndrome Definition There is as yet no agreed definition of APS but the consensus opinion seems to be that the following are required, although they need not be present simultaneously: recurrent thromboembolic events recurrent fetal loss livedo reticularis high titre sustained IgG anticardiolipin antibody or lupus anticoagulant with abnormal PTT . (NB a number of infections can induce anti-phospholipid antibodies eg syphilis, Lyme disease, HIV-1) Clinical syndromes Arterial occlusion syndromes arterial occlusion occurs as discrete episodes usually occurs in single rather than multiple vessels can affect any size of vessel in individual patients the size of vessel and the body area affected is usually consistent from episode to episode eg patients who have had a stroke tend to have recurrent strokes no recognised triggers Brain recurrence rate almost 20% per year small vessel occlusion leading to confusion Kidney modest proteinuria most common clinical manifestation hypertension haematuria and hypocomplementaemia not features renal insufficiency Catastrophic occlusion syndrome rare multiple widespread infarctions over days to weeks may be precipitated by viral infection or allergic reaction leukocytosis high levels of tissue enzymes intravascular coagulation resembles sepsis

52. Antiphospholipid Syndrome - Encyclopedia Article About Antiphospholipid Syndrome encyclopedia article about antiphospholipid syndrome. antiphospholipid syndrome in Free online English dictionary, thesaurus and encyclopedia. http://encyclopedia.thefreedictionary.com/Antiphospholipid syndrome

Dictionaries: General Computing Medical Legal Encyclopedia Antiphospholipid syndrome Word: Word Starts with Ends with Definition Antiphospholipid syndrome is a disorder of coagulation Coagulation is a fairly complex process by which liquid blood becomes solid clots. It is an important part of hemostasis where a damaged blood vessel is ultimately covered by a fibrin clot to stop blood loss. Disorders in coagulation can lead to hemorrhage, thrombosis, or embolism. Ordinarily coagulation is initiated within seconds after an injury occurs when platelets form a plug at the site of injury. This is called primary hemostasis . Following this, various plasma components, called clotting factors respond (in a complex cascade) to form fibrin strands which strengthen the platelet plug. Click the link for more information. , and causes thrombosis in both arteries Arteries are tubes that deliver blood from the heart to the tissues and organs of the body. The arterial system is a high-pressure system that must accommodate the systolic and diastolic pressures generated by the strong contractions of the heart's left ventricle. To withstand and adapt to these pressures the arteries are surrounded by a varying degree of smooth muscle which contracts or relaxes in response to adrenergic and other locally produced peptides. (See epinephrine, norepinephrine, alpha and beta receptors.)

53. Antiphospholipid Syndrome Health Search Engine, antiphospholipid syndrome, antiphospholipid syndrome rank 1000 Home Health antiphospholipid syndrome. Site Map http://www.thenewhealthfind.com/health/antiphospholipid syndrome

antiphospholipid syndrome Antiphospholipid Syndrome rank:       Directory   Home: Health: Conditions and Diseases: Immune Disorders: Auto-Immune: Antiphospholipid Syndrome (16) See Also: Health: Conditions and Diseases: Blood Disorders: Blood Coagulation Health: Reproductive Health: Pregnancy and Birth: Complications MCW Healthlink - An article about antiphospholipid syndrome with a discussion on diagnosis, symptoms and treatment are discussed. Med Students - A review about antiphospholipid syndrome , giving most importance on its clinical features, diagnosis and management. Southern Medical Association: Antiphospholipid Syndrome - Case study of a 32 year old woman who came to a hospital at 36 weeks pregnancy. University of Michigan Health System - A look at antiphospholipid syndrome Mycoplasmal rank:       Directory   Home: Health: Conditions and Diseases: Infectious Diseases: Mycoplasmal (24) Support Groups (2) The Institute of Molecular Medicine - A nonprofit institute dedicated to discovering new diagnostic and therapeutic solutions for chronic mycoplasma infections. Gulf War Syndrome and Mycoplasma - Selected articles on the relationship between mycoplasmas and gulf war syndrome Auto-Immune rank:       Directory   Home: Health: Conditions and Diseases: Immune Disorders: Auto-Immune (157) Addison's@ (18) Ankylosing Spondylitis@ (16) Antiphospholipid Syndrome (16) Barth Syndrome @ (3) Graves'@ (51) Hemolytic Anemia@ (97) IgA Nephropathy@ (11) Lupus Erythematosus, Systemic@ (69) Microscopic Polyangiitis (3) Multiple Sclerosis@ (257) Myasthenia Gravis (49) Myositis (24) Osteoporosis@ (70) Pemphigus@ (6) Psoriasis@ (50) Rheumatoid Arthritis@ (40) Sarcoidosis (33) Scleroderma@ (36) Sjogren's

54. Antiphospholipid Syndrome The New Health Directory, Directory, Home Health Conditions and Diseases Immune Disorders AutoImmune antiphospholipid syndrome (16) See Also http://www.thenewhealthfind.com/Health/ConditionsandDiseases/ImmuneDisorders/Aut

Directory Home Health Conditions and Diseases Immune Disorders ... Auto-Immune : Antiphospholipid Syndrome (16) See Also: Health: Conditions and Diseases: Blood Disorders: Blood Coagulation Health: Reproductive Health: Pregnancy and Birth: Complications MCW Healthlink - An article about antiphospholipid syndrome with a discussion on diagnosis, symptoms and treatment are discussed. Med Students - A review about antiphospholipid syndrome, giving most importance on its clinical features, diagnosis and management. Southern Medical Association: Antiphospholipid Syndrome - Case study of a 32 year old woman who came to a hospital at 36 weeks pregnancy. University of Michigan Health System - A look at antiphospholipid syndrome and the symptoms, cause of the blood clotting, diagnosis and treatment. Antiphospholipid Syndrome - A case study as well as in-depth look at this disease discussing treatment, diagnosis, ocular and systemic manifestations. Written by Erik Letko, M.D. Neuroland: Antiphospholipid Syndrome - Among the topics discussed are primary and secondary APS, clinical manifestations, treatment and further reading. Women's Health - A look at antiphospholipid syndrome, what it is, problems it can cause, if it can be prevented, how common it is, and what to do.

55. Health Library - antiphospholipid syndrome. Synonyms Disorder Subdivisions General Discussion Resources Synonyms. Antiphospholipid Antibody Syndrome; APLS; APS. http://yalenewhavenhealth.org/library/healthguide/IllnessConditions/topic.asp?hw

56. Antiphospholipid Syndrome antiphospholipid syndrome G. Karakatsanis, Dermatologist. antiphospholipid syndrome (APLS) 1999 American Heart Association,; antiphospholipid syndrome (APLS). http://www.edae.gr/antiphospholipid.html

HELLENIC ASSOCIATION DERMATOLOGY-VENEREOLOGY ANTIPHOSPHOLIPID SYNDROME G. Karakatsanis, Dermatologist. 1-12 ANTIPHOSPHOLIPID (HUGHES') SYNDROME A treatable cause of recurrent pregnancy loss. This syndrome was first described by Hughes in 1983. It is an important cause of thrombotic disease, both venous and arterial (especially recurrent cerebral ischemic attacks). Other features include mild thrombocytopenia, chorea, heart valve disease, livedo reticularis, and most commonly, recurrent pregnancy loss. AARDA - Antiphospholipid Syndrome Acquired Thrombophilia Antiphospholipid Antibody Syndrome Immune Problems. Alan E Beer, MD Joanne Kwak-Kim, MD , Joanne Kwak-Kim, MD, Evangelos Ntrivalas, MD , Hee Soo Chung MD American Autoimmune Related Diseases Association 1999 the American Autoimmune Related Diseases Association, Anti-[beta]2-glycoprotein I : a useful marker for the antiphospholipid syndrome ANTIBODY ASSOCIATED WITH AUTOIMMUNE DISORDERS FOUND TO "CLUSTER" IN FAMILIES Anticardiolipin antibodies David Tanne, MD Department of Neurology Chaim Sheba Medical Center. Tel Hashomer, Israel Anti-Phosphatidylserine (aPS) Antibodies ANTIPHOSPHOLIPID (HUGHES') SYNDROME A treatable cause of recurrent pregnancy loss.

57. Antiphospholipid Antibody Syndrome Antiphospholipid Antibody Syndrome antiphospholipid syndrome. Book, Home Page. http://www.fpnotebook.com/RHE18.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Rheumatology Diffuse Assorted Pages Amyloidosis Antiphospholipid Antibody Syndrome Systemic Lupus Erythematosus Polymyalgia Rheumatica ... Medication Causes of Myositis Antiphospholipid Antibody Syndrome Antiphospholipid Syndrome Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Rheumatology Index General Bone Cardiovascular Medicine Dermatology Diffuse Examination Infectious Disease Intra-Articular Disorders Laboratory Marfans Myofascial Neurology Osteoarthritis Pain Pediatrics Pharmacology Procedure Radiology RA Spondylitis Symptom Evaluation Page Diffuse Index Amyloidosis Behcet's Syndrome Lupus Anticoagulant Antiphospholipid Lupus Systemic Polymyalgia Rheumatica Polymyositis Background Polymyositis DDx Polymyositis Evaluation Polymyositis Management Polymyositis Types Idiopathic Sjogren's Syndrome Systemic Sclerosis Pathophysiology Recurrent thrombosis of any size vessel May have no link with SLE despite early associations Diagnosis Major clinical associations Venous thrombosis Deep Vein Thrombosis Pulmonary Embolism Arterial thrombosis Cerebrovascular Accident (CVA) Transient Ischemic Attack s Myocardial Infarction Gangrene

58. Antiphospholipid Syndrome antiphospholipid syndrome (APLS) is a rare autoimmune disorder characterized by recurring blood clots that usually appear before 45 years of age. http://www.bchealthguide.org/kbase/nord/nord985.htm

document.write(''); var hwPrint=1; var hwDocHWID="nord985"; var hwDocTitle="Antiphospholipid Syndrome"; var hwRank="1"; var hwSectionHWID="nord985"; var hwSectionTitle=""; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="NORD"; National Organization for Rare Disorders, Inc. Antiphospholipid Syndrome Important It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Antiphospholipid Antibody Syndrome APLS APS Disorder Subdivisions None Related Disorders List Information on the following diseases can be found in the Related Disorders section of this report: Polyarteritis Nodosa Takayasu Arteritis Giant Cell Arteritis Lupus Anticardiolipin (Antibody) Syndrome Stroke Essential Thrombocytopenia General Discussion Antiphospholipid Syndrome (APLS) is a rare autoimmune disorder characterized by recurring blood clots that usually appear before 45 years of age. It may also be associated with repeated spontaneous abortions for no apparent reason in young women. There may be a family history of blood clotting disorders in some cases. APS may occur in individuals with lupus or related autoimmune diseases or as a primary syndrome in otherwise healthy individuals. Symptoms Antiphospholipid Syndrome is a very rare autoimmune disorder characterized by the development of blood clots (thromboses) in veins and/or arteries at a young age. These clots may cause a stroke or short episodes of low oxygen supply to the brain (transient ischemic attacks or TIA) and the unexplained, repeated loss of pregnancies. In a small number of cases, there may be a family history of clotting diseases.

59. Arthritis: Catastrophic Antiphospholipid Syndrome (CAPS) OTHER TOPICS. SLE. Fibromyalgia. Sepsis. Catastrophic antiphospholipid syndrome (CAPS) Juan Javier Lichauco, MD, Jayashree Sinha, MD,, and Peter Barland, MD Drs. http://www.thedoctorwillseeyounow.com/articles/arthritis/caps_9/

IN THIS ARTICLE What is it? Symptoms Treatment The "morning after pill" will not terminate an already existing pregnancy. more... OTHER TOPICS SLE Fibromyalgia Sepsis Catastrophic Antiphospholipid Syndrome (CAPS) Juan Javier Lichauco, M.D., Jayashree Sinha, M.D., , and Peter Barland, M.D. Drs. Lichauco and Sinha are Fellows in Rheumatology, Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, New York. Drs. Lichauco, Sinha and Barland report no commercial conflicts of interest. A young woman is brought to the hospital with a frightening array of problems, any one of which could be fatal. Her kidneys and heart are barely functioning. She is having difficulty breathing and her skin is covered with purplish blotches. On top of all this, she seems mentally confused and may have had a stroke. At first, the doctors are stumped. Fearing some kind of virulent infection or poisoning, which might have caused these symptoms, they give the young woman antibiotics and dialysis treatment to aid her failing kidneys. Unfortunately, in this woman's case, the cause was neither infection nor poisoning but, instead, a rare and mysterious illness called CAPS, catastrophic antiphospholipid antibody syndrome. What Is It?

60. Antiphospholipid Syndrome (aPL) antiphospholipid syndrome (aPL). What is antiphospholipid syndrome (aPL)? antiphospholipid syndrome is an autoimmune disease in which http://www.chw.org/display/PPF/DocID/3247/router.asp

Systemic Lupus Erythematosus (SLE, or Lupus) Antiphospholipid Syndrome (aPL) Myasthenia Gravis Home ... Autoimmune Diseases : Antiphospholipid Syndrome (aPL) E-mail this page Print this page Antiphospholipid Syndrome (aPL) What is antiphospholipid syndrome (aPL)? Antiphospholipid syndrome is an autoimmune disease in which the body produces large amounts of antiphospholipid antibodies. Phospholipids are a special type of fat containing phosphate that makes up the outer walls of the body's cells. Antiphospholipid antibodies attack the phospholipids. This causes many different problems including increased blood clotting. Cardiolipin is one type of phospholipid and specific anticardiolipin antibodies may develop. This disease is about two times more common in women than men. It is generally characterized by the following: thrombosis - blood clots in arteries or veins (especially in the legs). Clots in vessels of the central nervous system (brain and spinal cord) can result in stroke. thrombocytopenia - low platelets (cells important in blood clotting).

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 3     41-60 of 97    Back | 1  | 2  | 3  | 4  | 5  | Next 20