Renal Biopsy Case History July, 1995 Clinical Summary A 64 year old man with a 15 year history of coronary artery disease and hypertension (treated with Hygroton 50mg/day), and a 5 year history of diabetes mellitus (treated with 25 units NPH insulin/day) was found to have 3+ proteinuria during a routine physical examination. Follow-up laboratory evaluation revealed: 9 g/day proteinuria, 2-3 RBC/hpf in the urine, serum creatinine 1.2 mg/dL (106 umol/L), creatinine clearance 77 mL/min (128 mL/s), BUN 20 mg/dL (7.0 mmol/L), cholesterol 300 mg/dL (7.76 mmol/L), albumin 3.1 g/dL (31 g/L), calcium 9.2 mg/dL (2.30 mmol/L), phosphorus 4.3 mg/dL (1.39 mmol/L), glucose 189 mg/dL (10.5 mmol/L), uric acid 9.5 mg/dL (565 umol/L), and normal LFTs. He was referred to a nephrologist for evaluation and treatment. Physical examination revealed weight 81.2 kg, blood pressure 100/72 mm Hg, no retinopathy and 1+ pitting edema in the lower extremities. Laboratory data included: 12 g/day proteinuria, 8-10 RBC/hpf in the urine | |
|