81. Alpha One Foundation Information about the organization, research, and news as well as alpha 1antitrypsin deficiency. http://www.alphaone.org/

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82. Alpha 1 Antitrypsin Deficiency - Lungs: Pulmonary And Respiratory Health And Med MedicineNet Home Diseases Conditions AZ List Lungs Home Alpha 1 antitrypsin deficiency. Advanced Search. Lungs Home. Alpha 1 antitrypsin deficiency Index. http://www.medicinenet.com/Alpha_1_Antitrypsin_Deficiency/article.htm

MedicineNet Home Lungs Home > Alpha 1 Antitrypsin Deficiency Advanced Search Printer-Friendly Format Add to Favorites Email to a Friend ... Next page Alpha-1 Antitrypsin Deficiency (A-1ATD) What is A-1ATD? How do normal lungs work? What happens if there isn't enough alpha-1 antitrypsin? How does smoking worsen lung damage caused by the disorder? ... Alpha-1 Antitrypsin Deficiency At A Glance What is A-1ATD? Alpha-1 antitrypsin is a protein that is made in the liver. The liver releases this protein into the bloodstream. Alpha-1 antitrypsin protects the lungs so they can work normally. Without enough alpha-1 antitrypsin, the lungs can be damaged, and this damage may make breathing difficult. In addition, liver damage (hepatitis, cirrhosis) can occur in both children and adults. Alpha-1 antitrypsin deficiency is an inherited (passed down from parents) disorder that causes low levels of, or no alpha-1 antitrypsin in the blood. How do normal lungs work? Air usually enters the nose and mouth and goes down the air tube (trachea) to two main air passages (bronchi). These passages allow air to go into the right and left lung.

83. Alpha1-Antitrypsin Deficiency Of Inherited Emphysema-Medfacts-National Jewish Me Alpha1antitrypsin deficiency of Inherited Emphysema. The inherited form of emphysema is called alpha1 antitrypsin deficiency or alpha - one for short. http://www.nationaljewish.org/medfacts/alpha1.html

Alpha1-Antitrypsin Deficiency of Inherited Emphysema Chronic obstructive pulmonary disease or COPD for short, is a lung disease that affects millions of people each year. COPD is a general term used to describe diseases such as emphysema and chronic bronchitis. In emphysema there is damage to the walls of the air sacs (alveoli) in the lungs. What is Inherited Emphysema? Most cases of emphysema are caused by smoking or other environmental factors. However, in a small number of cases of emphysema, there is a hereditary basis for the disease. The earliest symptom of emphysema is shortness of breath during activity. Later the shortness of breath occurs with rest also. The inherited form of emphysema is called alpha1 antitrypsin deficiency or "alpha - one" for short. People with this disease don't have enough of a major protein in the blood. This protein is alpha1 antitrypsin. Although there are many different genetic variations of this protein, only some will cause lung disease. It is more often seen in people of northern European descent, especially Scandinavians. What Does the Alpha1 Protein do in the Body?

84. THE MERCK MANUALSECOND HOME EDITION, Alpha1-Antitrypsin Sclerosing Cholangitis Alpha 1 antitrypsin deficiency. Alpha 1 -antitrypsin deficiency. Alpha 1 -antitrypsin deficiency is a hereditary http://www.merck.com/mrkshared/mmanual_home2/sec10/ch136/ch136f.jsp

85. Alpha1-Antitrypsin (A1AT) Deficiency Alpha 1antitrypsin deficiency-a model for conformational diseases. N Engl J Med. The cellular basis for liver injury in alpha 1-antitrypsin deficiency. http://www.clevelandclinicmeded.com/diseasemanagement/gastro/alpha1/alpha1.htm

Published August 13, 2002 Anthony S. Tavill, MD Department of Gastroenterology and Hepatology Print Chapter The Cleveland Clinic Foundation There are many inherited metabolic diseases that may have a pathologic impact on the liver. In many cases the liver component of these diseases is only an epiphenomenon of a more generalized systemic disorder. Examples of such epiphenomena are glycogen and lipid storage diseases in which hepatomegaly is a manifestation of the underlying metabolic defect although the liver is not necessarily the major target organ. However, there are three genetically determined diseases in which the liver may be the principal target organ, with manifestations of acute, subacute, or chronic disease that may become evident in early or later life. These are hereditary hemochromatosis (HH) , a major disorder of iron overload; Wilson's disease , a genetic disorder of copper overload; and alpha

86. Alpha 1-Antitrypsin Deficiency alpha 1antitrypsin deficiency. Image URL Alpha 1 anti trypsin deficiency, Image URL Alpha 1 anti-trypsin deficiency, Image URL Alpha 1 anti-trypsin deficiency, http://www.brisbio.ac.uk/ROADS/subject-listing/alpha1antitrypsindeficiency.html

A collection of medical, dental and veterinary images for use in teaching. Home About the Archive FAQ Terms and Conditions ... Help alpha 1-Antitrypsin Deficiency Alpha 1 anti trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency Alpha 1 anti-trypsin deficiency

87. Alpha 1-antitrypsin Deficiency - Wikipedia, The Free Encyclopedia Alpha 1antitrypsin deficiency. Alpha 1-antitrypsin deficiency (A1AD) is a genetic disorder caused by reduced levels of alpha 1-antitrypsin in blood. http://en.wikipedia.org/wiki/Alpha_1-antitrypsin_deficiency

Alpha 1-antitrypsin deficiency From Wikipedia, the free encyclopedia. Alpha 1-antitrypsin deficiency ) is a genetic disorder caused by reduced levels of alpha 1-antitrypsin in blood . It leads to pulmonary (lung) emphysema and, in severe cases, to liver disease. Table of contents 1 Signs and symptoms 2 Pathophysiology 3 Treatment 4 Epidemiology ... edit Signs and symptoms These are generally undistinguishable from the "normal" emphysema and cirrhosis edit Pathophysiology Please refer to the alpha 1-antitrypsin for the various protease inhibitor (Pi) genotypes and phenotypes Normally, alpha 1-antitrypsin is produced in the liver and exists in levels of 1.5-3.5 gram litre . When the levels are reduced (40-60%, in the PiSS, PiMZ and PiSZ phenotypes ), most people will only suffer symptoms if they smoke , as the levels are still sufficient to counteract "normal" elastase activity in inflammation . Only in the PiZZ phenotype, when the levels are less than 15%, emphysema develops at a young age, and 50% will develop liver cirrhosis due to the accumulated protein , which is not secreted properly. On

88. Alpha 1-antitrypsin Deficiency - Encyclopedia Article About Alpha 1-antitrypsin Alpha 1antitrypsin deficiency. Word Word. Some articles mentioning Alpha 1-antitrypsin deficiency http://encyclopedia.thefreedictionary.com/Alpha 1-antitrypsin deficiency

Dictionaries: General Computing Medical Legal Encyclopedia Alpha 1-antitrypsin deficiency Word: Word Starts with Ends with Definition Alpha 1-antitrypsin deficiency ) is a genetic disorder A genetic disorder , or genetic disease is a disease caused, at least in part, by the genes of the person with the disease. There are a number of possible causes for genetic defects: They may be caused by an unwelcome mutation, as are most cancers. There are genetic disorders caused by the accidental duplication of a chromosome, as in Down syndrome, or repeated duplication of part of a chromosome as in Fragile X syndrome. The defective genes are often inherited from the person's parents. In this case, the genetic disorder is known as a hereditary disease . This can often happen unxpectedly when two healthy carriers of a defective recessive gene reproduce, but can also happen when the defective gene is dominant. Click the link for more information. caused by reduced levels of alpha 1-antitrypsin Alpha 1-antitrypsin or -antitrypsin ) is a serine protease inhibitor (serpin). It protects tissue from enzymes from inflammatory cells, especially elastase. It is present in human blood at 1.5 - 3.5 gram/liter.

89. Alpha1-Antitrypsin Deficiency In COPD Alpha1antitrypsin deficiency in COPD Clinical Implications. from Medscape General early emphysema due to alpha 1 -antitrypsin deficiency (alpha 1 -ATD) is an http://www.medscape.com/viewarticle/408728

90. Cystic Fibrosis And Alpha 1 Antitrypsin Deficiency ROYAL COLLEGE OF SURGEONS IN IRELAND. CLIFFORD TAGGART CATHERINE GREENE. Cystic Fibrosis and Alpha 1 antitrypsin deficiency. Professor http://www.irishscientist.ie/2002/contents.asp?contentxml=02p175.xml&contentxsl=

91. NEWS Detail Therapy of a1 deficiency. In, Crystal RG, ed. Alpha1antitrypsin deficiency. Replacement therapy for alpha 1-antitrypsin deficiency associated wit emphysema. http://www.imj.ie/news_detail.php?nNewsId=2048&nVolId=70

92. PharmGKB: Alpha 1-Antitrypsin Deficiency Alternate Names Deficiencies, alpha 1antitrypsin; deficiency, alpha 1-antitrypsin; alpha 1 antitrypsin deficiency; alpha 1-antitrypsin Deficiencies. http://www.pharmgkb.org/do/serve?objId=PA446874&objCls=Disease

93. Genetic Modifiers Of Alpha 1-Antitrypsin Deficiency We are looking......Therapeutic Area Pulmonary. Indication COPD. Title Genetic Modifiers of Alpha 1antitrypsin deficiency. http://crnet.mgh.harvard.edu/clinical_trials/view_trial.asp?ct_id=668&clinic=&No

94. Scripta Academica Lundensis Dissertations From Home Search. Lung function in alpha1antitrypsin deficiency by Piitulainen, Eeva (1949). Document type Doctoral thesis Date published http://theses.lub.lu.se/postgrad/search.tkl?field_query1=pubid&query1=med_251&re

95. Boardhost: File Not Found have a deficiency of Alpha 1 Protein. The fact sheet at the link should answer some of your questions. Wes. Link Alpha1antitrypsin deficiency of Inherited http://members.boardhost.com/COPD/msg/71208.html

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96. Disease Category Listing (258): Alpha 1 Antitrypsin Deficiency Clinical Trials Alpha 1 antitrypsin deficiency. Massachusetts. Boston; Brigham and Womens Hospital Genetic Modifiers of Alpha 1antitrypsin deficiency. http://www.centerwatch.com/patient/studies/cat258.html

Clinical Trials: Alpha 1 Antitrypsin Deficiency Massachusetts Boston; Brigham and Womens Hospital Genetic Modifiers of Alpha 1-Antitrypsin Deficiency Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: June 1, 2004 at 2:59:35 PM Patient Resources: [ Trial Listing Notification Services Drug Directories About Clinical Research ... Patient Bookstore Professional Resources: [ Research Center Profiles Industry Provider Profiles Industry News Professional Resources ... Professional Bookstore General: [ Search Site Map Your Privacy CW World ... Home This site was developed in association with Illumina Interactive of Boston, MA

97. Home - American Lung Association Site TAKE ACTIONSend the Framework Convention on Tobacco Control to the Senate for Ratification (May 11, 2004) Health Effects of Ozone and Particle Pollution. The American Lung Association State of the http://www.lungusa.org/diseases/luna1ad.html

window.onload = RunScroller; Research Improving Lives American Lung Association scientific research saves and improves lives in every community in America. Through research we can eliminate lung disease and the suffering it causes millions of Americans. Read about how the American Lung Association changed Jan Martin's life. (May 21, 2004) Public Health Groups Strongly Support Bipartisan FDA Tobacco Legislation (May 20, 2004) Lung Association Applauds U.S. for Signing Global Tobacco Control Treaty (May 11, 2004) TAKE ACTION: Send the Framework Convention on Tobacco Control to the Senate for Ratification (May 11, 2004) Health Effects of Ozone and Particle Pollution The American Lung Association State of the Air: 2004 Knowing the truth about air pollution, and what you can do to help, is the first step in protecting you and your family's health. (April 29, 2004) TAKE ACTION: Defend the Clean Air Act! (April 29, 2004) New Asthma and Chronic Bronchitis Morbidity and Mortality Trend Reports View the latest additions to the Data and Statistics section of this site (April 2004) Research Applications Available for the American Lung Association's Nationwide Research Program 2005-2006 Celebrate our 100th Anniversary Support the American Lung Association's 21st Annual Research Fund Dinner!

98. Alpha Link - AlphaLink - Alphalink.org Information and resources for alpha link alphalink alpha link alpha link build a web site build web site create a web site create web site directory email http://www.alphalink.org/

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