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Gene Therapy: more books (100)

Understanding Gene Therapy (Medical Perspectives) by Prof Ni Lemoine, 1999-09-01
Gene Therapy, Volume 40 (Advances in Pharmacology)
Narrative Therapy: The Social Construction of Preferred Realities by Gene Combs, Jill Freedman, 1996-03-17
Gene Therapy (New Biology) by Joseph, Ph.D. Panno, 2010-09
Gene Therapy: The Use of DNA as a Drug
Special Report on Gene Therapy Companies by K. K. Jain, 2000-02-23
Gene Therapy in Lung Disease (Lung Biology in Health and Disease)
Cancer Gene Therapy (Contemporary Cancer Research)
Gene Therapy (Health and Medical Issues Today) by Evelyn B. Kelly, 2007-07-30
Animal Cell Technology: From Biopharmaceuticals to Gene Therapy
Stem Cell Biology and Gene Therapy
Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
Trends In Gene Therapy Research
Gene Therapy in the Treatment of Cancer: Progress and Prospects (Cancer: Clinical Science in Practice)

lists with details

European Society Of Gene Therapy
esgt.org, European Society of gene therapy If your browser sticks here, click here gene therapy, esgt.org, health/medical, European Society of.
http://www.esgt.org/
CysticFibrosis.com
Internet community for cystic fibrosis patients, families and loved ones. Information on clinical trials, gene therapy, testing, associations, research and events.
http://cysticfibrosis.com/

Extractions: Learn important information about daily living nutrition stories games ... snacks , and much more... CysticFibrosis.com latest Forum topics Families - Lots of questions, lots of fear Adults - Starting the xplant process, questions! ... Join our forums, it's compltely free! You may also post anonymously as well!
Gene Therapy - Wikipedia, The Free Encyclopedia
gene therapy is the insertion of genes into an individual's cells and tissues to treat a hereditary diseases in particular. gene therapy typically aims to supplement a defective
http://www.wikipedia.org/wiki/Gene_therapy

Extractions: Other languages: Dansk Deutsch Nederlands From Wikipedia, the free encyclopedia. Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease , and hereditary diseases in particular. Gene therapy typically aims to supplement a defective mutant allele with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is often lumped together with them. Table of contents showTocToggle("show","hide") 1 Background 6 External links In the 1980s, advances in molecular biology had already enabled human genes to be sequenced and cloned . Scientists looking for a method of easily producing proteins , such as the protein deficient in diabetics - insulin, investigated introducing human genes to bacterial DNA. The modified bacteria then produce the corresponding protein, which can be harvested and injected in people who cannot produce it naturally. Scientists took the logical step of trying to introduce genes straight into human cells, focusing on diseases caused by single-gene defects, such as
Frosst, Phyllis Ph.D
Postdoctoral fellow with experience in gene therapy, cell biology and human genetics.
http://www.scripps.edu/~phyllis/
Gene Therapy - An Overview
gene therapy An Overview. BIO. " Biotechnology in Perspective." Washington, D.C. Biotechnology Industry Organization, 1990. Altered Genes. Each of us carries about half a dozen defective genes. The types of gene therapy described thus far all have one factor in common that is, that the tissues being treated are
http://www.accessexcellence.org/AB/IWT/Gene_Therapy_Overview.html

Extractions: BIO. "Biotechnology in Perspective." Washington, D.C.: Biotechnology Industry Organization, 1990. Each of us carries about half a dozen defective genes. We remain blissfully unaware of this fact unless we, or one of our close relatives, are amongst the many millions who suffer from a genetic disease. About one in ten people has, or will develop at some later stage, an inherited genetic disorder, and approximately 2,800 specific conditions are known to be caused by defects (mutations) in just one of the patient's genes. Some single gene disorders are quite common - cystic fibrosis is found in one out of every 2,500 babies born in the Western World - and in total, diseases that can be traced to single gene defects account for about 5% of all admissions to children's hospitals. In the U.S. and Europe, there are exciting new programs to 'map' the entire human genome - all of our genes. This work will enable scientists and doctors to understand the genes that control all diseases to which the human race is prone, and hopefully develop new therapies to treat and predict diseases. Most of us do not suffer any harmful effects from our defective genes because we carry two copies of nearly all genes, one derived from our mother and the other from our father. The only exceptions to this rule are the genes found on the male sex chromosomes. Males have one X and one Y chromosome, the former from the mother and the latter from the father, so each cell has only one copy of the genes on these chromosomes. In the majority of cases, one normal gene is sufficient to avoid all the symptoms of disease. If the potentially harmful gene is recessive, then its normal counterpart will carry out all the tasks assigned to both. Only if we inherit from our parents two copies of the same recessive gene will a disease develop.
Human Gene Therapy
Human gene therapy. Some commentators on gene therapy have objected to any form of genetic manipulation, no matter how wellintentioned (VII, Rifkin 1983).
http://www.georgetown.edu/research/nrcbl/scopenotes/sn24.html

Extractions: I. Background On September 14, 1990 researchers at the U.S. National Institutes of Health performed the first (approved) gene therapy procedure on four-year old Ashanti DeSilva. Born with a rare genetic disease called severe combined immune deficiency (SCID), she lacked a healthy immune system, and was vulnerable to every passing germ. Children with this illness usually develop overwhelming infections and rarely survive to adulthood; a common childhood illness like chickenpox is life-threatening. Ashanti led a cloistered existenceavoiding contact with people outside her family, remaining in the sterile environment of her home, and battling frequent illnesses with massive amounts of antibiotics. In Ashanti's gene therapy procedure, doctors removed white blood cells from the child's body, let the cells grow in the lab, inserted the missing gene into the cells, and then infused the genetically modified blood cells back into the patient's bloodstream. Laboratory tests have shown that the therapy strengthened Ashanti's immune system; she no longer has recurrent colds, she has been allowed to attend school, and she was immunized against whooping cough. This procedure was not a cure; the white blood cells treated genetically only work for a few months, and the process must be repeated every few months.
Leaders In Plasmid DNA Production, Recombinant Proteins And Vector Development
NTC is a technologybased molecular biology and gene therapy service company, providing plasmid DNA manufacturing services, recombinant protein manufacturing
http://www.natx.com/
CNN.com - Gene Therapy Successful In Treating Hemophilia B, Researchers Say - Ma
http://www.cnn.com/2000/HEALTH/03/01/goodgene.therapy/index.html
CNN - FDA To Defend Closure Of Gene Therapy Trials To Senate Subcommittee - Febr
http://www.cnn.com/2000/HEALTH/02/02/gene.therapy.01/index.html

Extractions: Web posted at: 10:20 a.m. EST (1520 GMT) From Medical Correspondent Elizabeth Cohen (CNN) A Senate subcommittee will be hearing testimony Wednesday into whether the Food and Drug Administration did the right thing in shutting down gene therapy trials at the University of Pennsylvania after a patient's death. Eighteen-year-old Jesse Gelsinger of Tucson, Arizona, died in September after receiving an experimental gene therapy at the University of Pennsylvania for an inherited liver disease. On January 21, the FDA, citing numerous research regulation violations, shut down gene therapy and other clinical trials at the University of Pennsylvania.
CNN.com - Gene Therapy For Cancer? - August 1, 2000
http://www.cnn.com/2000/HEALTH/cancer/08/01/cancer.gene.therapy/index.html
Gene Therapy - An Overview
gene therapy An Overview. BIO. Biotechnology in Perspective. Washington, DC Biotechnology Industry Organization, 1990. Altered Genes. gene therapy.
http://www.accessexcellence.org/AB/BA/Gene_Therapy_Overview.html

Extractions: BIO. "Biotechnology in Perspective." Washington, D.C.: Biotechnology Industry Organization, 1990. Each of us carries about half a dozen defective genes. We remain blissfully unaware of this fact unless we, or one of our close relatives, are amongst the many millions who suffer from a genetic disease. About one in ten people has, or will develop at some later stage, an inherited genetic disorder, and approximately 2,800 specific conditions are known to be caused by defects (mutations) in just one of the patient's genes. Some single gene disorders are quite common - cystic fibrosis is found in one out of every 2,500 babies born in the Western World - and in total, diseases that can be traced to single gene defects account for about 5% of all admissions to children's hospitals. In the U.S. and Europe, there are exciting new programs to 'map' the entire human genome - all of our genes. This work will enable scientists and doctors to understand the genes that control all diseases to which the human race is prone, and hopefully develop new therapies to treat and predict diseases. Most of us do not suffer any harmful effects from our defective genes because we carry two copies of nearly all genes, one derived from our mother and the other from our father. The only exceptions to this rule are the genes found on the male sex chromosomes. Males have one X and one Y chromosome, the former from the mother and the latter from the father, so each cell has only one copy of the genes on these chromosomes. In the majority of cases, one normal gene is sufficient to avoid all the symptoms of disease. If the potentially harmful gene is recessive, then its normal counterpart will carry out all the tasks assigned to both. Only if we inherit from our parents two copies of the same recessive gene will a disease develop.
Laboratory Of Gene Therapy Research - Rigshospitalet
Focusing on C/EBPa in growth arrest, differentiation and cancer, and nonsensemediated mRNA decay in development, RNA traffic and disease, at Copenhagen University Hospital, Denmark.
http://www.labgenterapi.dk
Cancer Gene Therapy
Supported by the International Society for Cancer gene therapy, this resource publishes original research and hosts diverse views.
http://www.naturesj.com/cgt/index.html

Extractions: nature.com about npg nature science update naturejobs ... site index SEARCH my account e-alerts subscribe register ... Journal home For readers Content Advance online publication Online sample issue E-alerts ... Society publishing NPG Subject areas Access material from all our publications in your subject area: Biotechnology Cancer Chemistry Clinical Medicine ... Microbiology NEW! Molecular Cell Biology Neuroscience Pharmacology Physics View tables of contents The essential gene therapy resource for cancer researchers and clinicians Pertinent and practical, the Journal keeps its readers up to date with the latest developments in gene therapy for cancer Presents diverse viewpoints from academic, industry, and regulatory perspectives Publishes original laboratory and clinical research papers, case reports and review articles Topics covered include: antisense technology; drug resistance; hematopoietic gene transfer; homologous recombination; ribozyme technology; tumor immunotherapy; tumor suppressors
Ingenta Select
www.catchword.com/rpsv/catchword/mal/10430342/contp11.htm gene therapy for X-linked severe combined immune deficiency(X-SCID
http://www.catchword.com/titles/10430342.htm

Extractions: Human Gene Therapy is available online via Ingenta Select. There are currently 96 issues available for viewing. You can browse the contents pages of online issues free of charge. Please note that, in order to view the full text of online articles, you will need to follow the steps below. The May 1st 2004 issue is available free of charge. If you would like to receive an email notification of the Table of Contents for each new online issue of Human Gene Therapy please enter your email address below:
The International Symposium On Molecular Diagnostics Skin Gene Therapy
Topics include chip technology and proteomics, targeting strategies, skin gene transfer, updates on vector systems, and inhibiting viral systems. March 27 29, 2003, D¼sseldorf, Germany.
http://www.isgt-congress.org/
UNC Gene Therapy Center
The UNC gene therapy Center utilizes the adenoassociated virus (AAV) in the quest to develop an efficient viral vector system for use in human gene therapy.
http://www.med.unc.edu/wrkunits/3ctrpgm/genether/welcome.htm

Extractions: Click here to learn more about our gene therapy research. Announcements March 2004 Drs. Stilwell and Samulski published a breakthrough study on the safety of AAV virion shells. They found that viral capsids may influence gene expression independent from their packaged DNA. AAV and adenovirus were compared using DNA microarrays for their effects on cellular gene expression. AAV was found to have minimal impact on gene expression in the cell, while adenovirus activated the expression of genes associated with toxicity and the immune response. These findings indicate that AAV may be a safer and more effective form of transduction. Click here for more information about this study Fall 2003 - The UNC Gene Therapy Center was featured in Endeavors Magazine for our work with Canavan Disease. Click here to learn more and read the article
Carl C. Icahn Center For Gene Therapy And Molecular Medicine
Anticipating new horizons of biomedical research, our department was established in 1996 at Mount Sinai School of Medicine to promote and accelerate the science and technology of gene/cellular therapeutics.
http://www.genetherapy-mssm.net/home.php
CBER - Cellular & Gene Therapy
Cellular gene therapy. The Center for Biologics FDA has not yet approved any human gene therapy product for sale. However, the amount of
http://www.fda.gov/cber/gene.htm

Extractions: FDA Home Page CBER A-Z Index CBER Search Contact CBER ... CBER Home Page The Center for Biologics Evaluation and Research (CBER) regulates human gene therapy products - products that introduce genetic material into the body to replace faulty or missing genetic material, thus treating or curing a disease or abnormal medical condition. CBER uses both the Public Health Service Act and the Federal Food Drug and Cosmetic Act as enabling statutes for oversight. FDA has not yet approved any human gene therapy product for sale. However, the amount of gene-related research and development occurring in the United States continues to grow at a fast rate and FDA is actively involved in overseeing this activity. FDA has received many requests from medical researchers and manufacturers to study gene therapy and to develop gene therapy products. Such research could lead to gene-based treatments for cancer, cystic fibrosis, heart disease, hemophilia, wounds, infectious diseases such as AIDS, and graft-versus-host disease. Cellular Therapy: Potential Treatment for Heart Disease New Human Gene Transfer Research Data System Type I Diabetes / Pancreatic Islet Transplantation Use of Cloning Technology to Clone a Human Being Biol Resp Modifiers Adv Comm Publications Warning Letters Xenotransplantation Action Plan ... GT Patient Tracking System Updated March 26, 2004
Licensing Medical Implanting Technology To Biotech And Pharma Companies
Implants for pharmaceutical and gene therapy controlled release pellets, brachytherapy seeds, and chip and nanodevices.
http://www.NjeX.com/
Fundamentals Of Gene Therapy
Fundamentals of gene therapy. You look a little like your mother and a little like your father because of the genes they gave to you.
http://www.fda.gov/fdac/features/2000/gene.html

Extractions: Recently, French researchers reported dramatic results in treating a disease called severe combined immune deficiency (SCID), the disorder suffered by David, The Boy in the Bubble. A broken gene eliminates the production of an enzyme essential for the development of a normal immune system. Scientists isolated the normal copy of the gene and packaged it into a vector. In the laboratory, they then used the vector to transport the gene into the patient's own bone marrow cells. Bone marrow cells create the immune system. The treated bone marrow cells are then given back to the patient in a germ-free isolation room, where they reconstitute a normal, functioning immune system, freeing the patient from the need to remain in isolation.

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