Frederick Sanger - Les Membres De L'Académie Des Sciences Translate this page sanger (frederick). Chercheur honoraire au Conseil de la recherche médicale deCambridge. Né le 13 août 1918, élu Associé étranger le 9 février 1981. http://www.academie-sciences.fr/membres/S/Sanger_Frederick.htm
MSN Encarta - Sanger, Frederick Translate this page sanger, frederick. sanger, frederick (*1918), britischer Biochemiker und zweifacherNobelpreisträger. Multimedia. Erfahren Sie mehr über sanger, frederick aus, http://de.encarta.msn.com/encyclopedia_761574882/Sanger_Frederick.html
Frederick Sanger -- Britannica Concise Encyclopedia Online Article Britannica Concise Encyclopedia, sanger, frederick Britannica Concise. To cite thispage MLA style frederick sanger. Britannica Concise Encyclopedia. 2004. http://concise.britannica.com/ebc/article?eu=402983
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Frederick Sanger - Reference Library frederick sanger. frederick sanger (1918 ) is a British molecular biologistwho was working on problems related to the determination http://www.campusprogram.com/reference/en/wikipedia/f/fr/frederick_sanger.html
Extractions: Main Page See live article Alphabetical index Frederick Sanger - ) is a British molecular biologist who was working on problems related to the determination of the structure of proteins . His studies resulted in the determination of the structure of insulin ; for this discovery he received Nobel Prize in Chemistry in In , he developed the chain termination method , also known as the "Sanger method." He later received another Nobel Prize in Chemistry in "for contributions concerning the determination of base sequences in nucleic acids." In 1992, the Sanger Centre in Cambridge, named after Frederick Sanger, was founded by the Wellcome Trust and the British Medical Research Council, the purpose of which is stated on their website as "to provide a major focus in the UK for mapping and sequencing the human genome, and genomes of other organisms." Links: A brief biography about the 1958 Nobel Prize About the 1980 Nobel Prize The Sanger Centre
Caramba! - Nobelova Cena - Chemie (1943-1963) 1957. Todd, Alexander RI; Todd, Alexander R. II. 1958. sanger, frederickI. sanger, frederick II. sanger, frederick III. 1959. Heyrovský http://www.caramba.cz/page.php?PgID=953
Caramba! - Nobelova Cena - Chemie (1964-1984) 1980. Berg, Paul I. Berg, Paul II. Gilbert, Walter I. Gilbert, Walter II. sanger,frederick I. sanger, frederick II. 1981. Fukui, Kenichi I. Fukui, Kenichi II. http://www.caramba.cz/page.php?PgID=954
Frederick Sanger (1955) 1955. frederick sanger (Cambridge) determines the sequence of aminoacids in insulin (Nobel Prize for Chemistry 1958) Image reference. http://www.bioss.sari.ac.uk/~dirk/genomeOdyssey/go_1955.html
HighBeam Research: Search Results: Article sanger, frederick (1918 ). The Hutchinson Dictionary of ScientificBiography; 1/1/1998. Read the Full Article, Get a FREE Trial for http://www.highbeam.com/library/doc0.asp?DOCID=1P1:28910066&num=7&ctrlInfo=Round
HighBeam Research: ELibrary Search: Results 4. sanger, frederick (1918 ) The Hutchinson Dictionary of Scientific Biography;January 1, 1998 sanger, frederick (1918- ) is a British http://www.highbeam.com/library/search.asp?FN=AO&refid=ency_refd&search_thesauru
Frederick Sanger Definition Meaning Information Explanation frederick sanger definition, meaning and explanation and more about fredericksanger. FreeDefinition - Online Glossary and Encyclopedia, frederick sanger. http://www.free-definition.com/Frederick-Sanger.html
Extractions: Google News about your search term Frederick Sanger - ) is a British molecular biologist who was working on problems related to the determination of the structure of protein s. His studies resulted in the determination of the structure of insulin ; for this discovery he received Nobel Prize in Chemistry in In , he developed the chain termination method , also known as the "Sanger method." He later received another Nobel Prize in Chemistry in "for contributions concerning the determination of base sequences in nucleic acids." In 1992, the Sanger Centre in Cambridge, named after Frederick Sanger, was founded by the Wellcome Trust and the British Medical Research Council, the purpose of which is stated on their website as "to provide a major focus in the UK for mapping and sequencing the human genome, and genomes of other organisms." Links: Books about 'Frederick Sanger' at: amazon.com
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Extractions: Fred Sanger and his colleagues developed many of the techniques still used in genomic biology to this day. The fundamental method of 'reading' DNA using special bases called chain terminators, the use of very thin gel systems, the adaptation of efficient cloning methods to produce both DNA strands and the whole-genome shotgun were all developed by Fred and his group during the 1970s. Fred's group produced the first DNA whole genome sequence (for a virus called phiX174 that grows in bacteria) of just over 5000 base-pairs. They went on to sequence the first human genome (albeit that of the DNA in mitochondria - small energy factories in all our cells that have their own genome of about 16,000 base-pairs) and the genome of an important virus for molecular biology, bacteriophage lambda, in 1982. To sequence this virus genome - about 48,000 base-pairs - Fred developed the whole-genome shotgun method. The sequence of lambda was the first whole-genome shotgun. Fred was born towards the end of the First World War in Gloucestershire, UK. His father was a GP from whom he gained an interest in biology. Fred took his first degree at
Frederick Sanger (1918-), Biochemist National Portrait Gallery, list of portraits for frederick sanger including fredericksanger by Liam Woon, frederick sanger by Paula A. MacArthur, frederick http://www.npg.org.uk/live/search/person.asp?LinkID=mp06016
NPG 6151; Frederick Sanger NPG 6151 frederick sanger, NPG 6151 frederick sanger by Paula A. MacArthurDate 1991 Medium oil on canvas Measurements 53 7/8 in. x 53 7/8 in. http://www.npg.org.uk/live/search/portrait.asp?mkey=mw08253
Ôðåäåðèê Ñåíãåð (Frederick Sanger) The summary for this Russian page contains characters that cannot be correctly displayed in this language/character set. http://www.peoples.ru/science/chemistry/sanger/
Extractions: Frederick Sanger e la struttura dell'insulina (I) Fra gli scienziati l'ironia è una dote rara, rarissima nella versione dell'autoironia. Lungo i quaranta anni dedicati alla biochimica Frederick Sanger ne ha fatto abbondante uso (per se stesso) e dono (ai suoi collaboratori), giungendo ad un risultato accademico ineguagliato: due premi Nobel per la chimica, nel 1958 e nel 1980. L'incontro di Sanger con le proteine avvenne durante le ricerche per il PhD, condotte fra il 1940 e il 1943 nel Dipartimento di Biochimica di Cambridge. Secondo quanto ha scritto lo stesso Sanger, molto probabilmente non avrebbe mai potuto studiare in quella prestigiosa università se i suoi genitori "non fossero stati discretamente ricchi", perché il giovane non era "accademicamente brillante". In realtà gli mancava semplicemente ciò che noi chiamiamo 'parlantina', dato che i suoi insegnanti al termine di un anno supplementare di studi in biochimica gli diedero un first grade degree . Subito dopo (1940) Sanger fece due mosse fondamentali: si sposò - a ventidue anni - e fu accettato come allievo per il dottorato, aiutato in questo dalla duplice fortunata circostanza di essere esentato dagli obblighi militari in quanto obbiettore di coscienza, e di non aver bisogno di un aiuto finanziario in quanto benestante. Il lavoro per la tesi di dottorato, sul metabolismo della lisina, lo familiarizzò con la chimica degli amminoacidi, così che al momento dell'arrivo del nuovo direttore del Dipartimento Sanger potè inserisi nel filone di ricerca principale. Infatti A.C. Chibnall, il nuovo direttore e successore del grande Hopkins (premio Nobel per la scoperta delle vitamine), aveva portato con sé dall'Imperial College numerosi collaboratori ed una solida ricerca sull'insulina.
Extractions: Frederick Sanger e la struttura dell'insulina (II) Tornato in Inghilterra Sanger si ritrovò al punto di partenza e si risolse a separare le due catene con i metodi collaudati della precipitazione frazionata. La frazione A, corrispondente al 'terminale' glicina risultò contenere circa 20 amminoacidi, mentre la frazione B, corrispondente all'altro 'terminale' fenilalaninico, ne conteneva circa 30. Contrariamente alle aspettative la catena B risultò di più facile soluzione, mediante l'uso abile della idrolisi acida e dell'FDNB. In effetti Sanger e i suoi inventarono e risolsero un geniale puzzle , basato sull'isolamento, l'analisi e la 'connessione' dei tanti frammenti ottenuti: venivano eseguiti dei frazionamenti preliminari (ionoforesi, cromatografia per scambio ionico, adsorbimento su carbone), poi le frazioni contenenti da 5 a 20 peptidi venivano sottoposte a cromatografia su carta bidimensionale. Le 'macchie' venivano ritagliate, il materiale eluito, sottoposto a idrolisi completa e analizzato negli aminoacidi costituenti. Vorrei fare un esempio semplice delle mosse tipiche di questo 'gioco'. In una certa frazione particolarmente acida erano presenti solo sei peptidi diversi, ciascuno dei quali conteneva acido cisteico; poiché a sua volta la catena B aveva solo due residui cisteici tutte le sequenze si dovevano ridurre a due soltanto. Due peptidi davano indicazioni immediate: Val.CySO
Frederick Sanger - InformationBlast frederick sanger Information Blast. frederick sanger. frederick sanger(born 1918) is a British molecular biologist who was working http://www.informationblast.com/Frederick_Sanger.html
Extractions: Frederick Sanger OM (born August 13 ) is a British molecular biologist who was working on problems related to the determination of the structure of proteins . His studies resulted in the determination of the structure of insulin ; for this discovery he received Nobel Prize in Chemistry in In , he developed the chain termination method , also known as the "Sanger method." He later received another Nobel Prize in Chemistry in "for contributions concerning the determination of base sequences in nucleic acids." In 1992, the Sanger Centre in Cambridge, named after Frederick Sanger, was founded by the Wellcome Trust and the British Medical Research Council, the purpose of which is stated on their website as "to provide a major focus in the UK for mapping and sequencing the human genome, and genomes of other organisms." Categories: Nobel Prize in Chemistry winners Wikipedia is available under the terms of the GNU Free Documentation License