Bert Sakmann Bert Sakmann. Along with Erwin Neher, Bert Sakmann developed the patchclamp technique to record the small ionic currents (only a http://web.sfn.org/wrensite/projects/patch_clamp/sakmann.htm
Extractions: Along with Erwin Neher , Bert Sakmann developed the patch clamp technique to record the small ionic currents (only a few picoamperes) that flow through a single ion channel in neuronal membranes. In 1976 Sakmann and Neher made the first recordings of single ion channel currents in nicotinic acetylcholine receptors from muscle. They were awarded the Nobel Prize for this work in 1991. Current work in Professor Sakmann's group is focused on understanding fast signaling in neurons, including biophysical and molecular mechanisms underlying synaptic transmission. Biographical Sketch: Discovery H O M E B A S I C S O B J E C T I V E S ... A P P L I C A T I O N S
Bert Sakmann Bert Sakmann. Bert Sakmann (1942) German medical doctor and researchscientist who in 1991, together with German physicist Erwin http://www.nobel-winners.com/Medicine/bert_sakmann.html
Extractions: German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher, won the Nobel Prize for Physiology or Medicine for research into basic cell function and for their development of the patch-clamp techniquea laboratory method widely used in cell biology and neuroscience to detect electrical currents as small as a trillionth of an ampere through cell membranes. From 1969 to 1970 Sakmann served as a research assistant in the department of neurophysiology at the Max Planck Institute for Psychiatry and then finished his postdoctoral studies in the department of biophysics at University College, London. After receiving his medical degree from the University of Gottingen in 1974, Sakmann joined the department of neurobiology at the Max Planck Institute for Biophysical Chemistry, where he shared laboratory space with Neher. Working together, the two men used the patch-clamp technique to conclusively establish the existence of characteristic sets of ion channels in cell membranessome of which permit the flow of only positive ions, while others pass only negatively charged ions. This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders. These discoveries enabled the development of new and more specific drug therapies.
Especiales Diario Médico Translate this page Bert Sakmann y Erwin Neher. Bert Sakmann. Bert sakmann bert Sakmann nació en 1942en en Stuttgart (Alemania). Estudió Medicina en la Universidad de Gottingen. http://www.diariomedico.com/medicinasiglo/nobel1991.html
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LT Awardees CARLETON Alan (FRANCE) sakmann bert (Host Supervisor) Department of Cell Physiology Max-Planck-Institute for Medical Research - HEIDELBERG - GERMANY In vivo http://www.hfsp.org/awardees/AwardsLT2003.php
Extractions: Human Frontier Science Program The awards are listed alphabetically by principal applicant. You can use your browser's "find" function to locate specific keywords on this page. Return to Long-Term Fellows top page AMADOR Virginia (SPAIN) PAGANO Michele (Host Supervisor) Pathology Department - New York University - NEW YORK - USA Study of the function of human Fbl4, an F-box protein localized on the centrosomes abstract BACHAND François (CANADA) SILVER Pamela A. (Host Supervisor) Dept. of Cancer Biology and Biological Chemistry and Molecular Pharmacology - Dana Farber Cancer Institute - BOSTON - USA The role of protein methylation in the regulation of gene expression and growth control abstract BARDIN Allison (USA) SCHWEISGUTH François (Host Supervisor) Département de Biologie - Ecole Normale Supérieure - PARIS - FRANCE Investigating neuralized regulation during asymmetric cell division in Drosophila melanogaster abstract BECAMEL Carine (FRANCE) MALINOW Roberto (Host Supervisor) Department of Neuroscience - Cold Spring Harbor Laboratory - COLD SPRING HARBOR - USA Molecular mechanisms controlling AMPA receptor synaptic delivery abstract BECSKEI Attila (HUNGARY) VAN OUDENAARDEN Alexander (Host Supervisor) Department of Physics - Massachusetts Institute of Technology - CAMBRIDGE - USA Spatial dynamics of kinase and phosphatase reactions abstract BERDNIK Daniela (AUSTRIA)
Long-Term Fellows 1999 Brain HOFFMAN Dax (USA) (Fellow) sakmann bert (Host) Department of Cell Physiology, MaxPlanck-Institutefor Medical Research, Heidelberg, GERMANY Construction and http://www.hfsp.org/awardees/AwardsLTB1999.htm
Extractions: @import "/style/hfsp.css"; June 5, 2004 Home About HFSP How to Apply Awardees ... For Awardees Only The awards are listed alphabetically by principal applicant. You can use your browser's "find" function to locate specific keywords on this page. Return to Long-Term Fellows top page AKASSOGLOU Katerina (GREECE) (Fellow)
Bert Sakmann Toys Games. Click Here. Encyclopedia. Main Page See live article,Bert Sakmann. Bert Sakmann is a German cell physiologist. He http://www.sciencedaily.com/encyclopedia/bert_sakmann
Extractions: Front Page Today's Digest Week in Review Email Updates ... Outdoor Living Main Page See live article Bert Sakmann is a German cell physiologist. He shared the Nobel Prize in Physiology or Medicine with Erwin Neher in for their work on "the function of single ion channels in cells." This article is a stub. You can help Wikipedia by expanding it.
Maandoverzicht Aanwinsten MBU Aanwinstdatum 12MAR-04. Auteur sakmann bert. Titel Single-channel recordinged. by Bert Sakmann and Erwin Neher. Plaats New York, NY. Jaar 1995. http://alephuitvoer.library.uu.nl:8000/pub/aanwinst/archief/maa/MBU-MBUBK.htm
Bert Sakmann - Autobiography bert sakmann Autobiography. I was born during the second world war in Stuttgart, the capital of Swebia, as My father, bertold sakmann, was the director of a theatre, the third http://www.nobel.se/medicine/laureates/1991/sakmann-autobio.html
Extractions: I was born during the second world war in Stuttgart, the capital of Swebia, as the first of two children. My father, Bertold Sakmann, was the director of a theatre, the third son of a physician whose family had lived in southern Germany for several generations. My mother, Annemarie Sakmann, was a physiotherapist and was born in Bangkok, the second child of a Prussian physician who served as doctor to the King of Siam and was the founder of the first hospital in Siam. During the first half of my childhood I grew up in Lindau, on Lake Constance, in a completely rural environment. There I went to elementary school, before returning to Stuttgart where I completed my Abitur at the Wagenburg Gymnasium. My only real interests at school were the physics lessons. At home I spent most of my time designing and building model motor and sailing ships as well as remote control aeroplanes. It was generally assumed that I would become an engineer. In the final year of school however I learned about cybernetics and its possible application to biology. Cybernetics fascinated me, because it seemed to me that living organisms could be understood in engineering terms. Munich Technical University . After three years of experimental work on the neurophysiological basis of light adaptation in the cat's visual system I realized that the central nervous system (CNS) was too difficult to comprehend without understanding the synaptic connections more clearly. I went to a course on basic mechanisms of vision in a summer school and I attended a lecture given by
Sakmann, Bert sakmann, bert. ( b. June 12, 1942, Stuttgart, Ger From 1969 to 1970 sakmann served as a research assistant in the department of neurophysiology at the Max Planck http://www.britannica.com/nobel/micro/519_58.html
Extractions: (b. June 12, 1942, Stuttgart, Ger.), German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher , won the Nobel Prize for Physiology or Medicine for research into basic cell function and for their development of the patch-clamp techniquea laboratory method widely used in cell biology and neuroscience to detect electrical currents as small as a trillionth of an ampere through cell membranes. Working together, the two men used the patch-clamp technique to conclusively establish the existence of characteristic sets of ion channels in cell membranessome of which permit the flow of only positive ions, while others pass only negatively charged ions. This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders. These discoveries enabled the development of new and more specific drug therapies. In 1979 Sakmann became a research associate in the Max Planck Institute's membrane biology group. He was made head of the membrane physiology unit in 1983, and he became director of the institute's department of cell physiology two years later.
Medicine 1991 for their discoveries concerning the function of single ion channels incells . Erwin Neher, bert sakmann. 1/2 of the prize, 1/2 of the prize. http://www.nobel.se/medicine/laureates/1991/
Bert Sakmann Winner Of The 1991 Nobel Prize In Medicine bert sakmann, a Nobel Prize Laureate in Physiology and Medicine, at the NobelPrize Internet Archive. bert sakmann. 1991 Nobel Laureate in Medicine http://almaz.com/nobel/medicine/1991b.html
Bert Sakmann Invented patch clamping. Has a huge and active lab interested in cellular and systems neuroscience. Use patch clamping in slices and intact animals as well as two photon imaging. http://sunny.mpimf-heidelberg.mpg.de/shared/docs/departments/02/index.php3?LANG=
Bert Sakmann Winner Of The 1991 Nobel Prize In Medicine bert sakmann, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. bert sakmann. 1991 Nobel Laureate in Medicine http://www.almaz.com/nobel/medicine/1991b.html
Index Of Nobel Laureates In Medicine Rodbell, Martin, 1994. Ross, Sir Ronald, 1902. Rous, Peyton, 1966. sakmann, bert,1991. Samuelsson, Bengt I. 1982. Schally, Andrew V. 1977. Sharp, Phillip A. 1993. http://almaz.com/nobel/medicine/alpha.html
Books By Bert Sakmann At Walmart.com - Every Day Low Prices Find books written by bert sakmann. Select from 1000's of books at Walmart.com, we have a great selection of highquality merchandise, friendly service and, of course, Every Day Low Prices. Gift http://rdre1.inktomi.com/click?u=http://na.link.decdna.net/n/3532/4200/www.walma
Publications SingleChannel Recording, edited by bert sakmann and Erwin Neher http://sun0.mpimf-heidelberg.mpg.de/Publications.html
Sakmann, Bert -- Britannica Student Encyclopedia sakmann, bert Britannica Student Encyclopedia. MLA style sakmann, bert. BritannicaStudent Encyclopedia. 2004. Encyclopædia Britannica Premium Service. http://www.britannica.com/ebi/article?eu=337905&query=max planck&ct=ebi
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J Physiol -- Abstracts: Ohana And Sakmann 513 (1): 135 Ohana, O. sakmann, B. Download to Citation Manager Ora Ohana and bert sakmann. Abteilung Zellphysiologie, MaxPlanck-Institut für medizinische Forschung, Jahnstraße 29 http://www.jphysiol.org/cgi/content/abstract/513/1/135
Extractions: Ohana, O. Sakmann, B. Download to Citation Manager The Journal of Physiology pp. Dual whole-cell voltage recordings were made from synaptically connected layer 5 (L5) pyramidal neurones in slices of the young (P14-P16) rat neocortex. The Ca buffers BAPTA or EGTA were loaded into the presynaptic neurone via the pipette recording from the presynaptic neurone to examine their effect on the mean and the coefficient of variation (c.v.) of single fibre EPSP amplitudes, referred to as unitary EPSPs. The fast Ca buffer BAPTA reduced unitary EPSP amplitudes in a concentration dependent way. With 0·1 mM BAPTA in the pipette, the mean EPSP amplitude was reduced by 14 ± 2·8 % (mean ± s.e.m., n = 7) compared with control pipette solution, whereas with 1·5 mM BAPTA, the mean EPSP amplitude was reduced by 72 ± 1·5 % (