81. Entrez PubMed 2002 Jan 10;415(6868)1234. Click here to read Systematic identificationof protein complexes in saccharomyces cerevisiae by mass spectrometry. http://www.biomedcentral.com/pubmed/11805837

Entrez PubMed Nucleotide Protein ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes 3D Domains Domains Gene GEO GEO DataSets HomoloGene Journals MeSH NCBI Web Site OMIM PMC PopSet SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard ... Text Version Entrez PubMed Overview FAQ Tutorial New/Noteworthy ... E-Utilities PubMed Services Journals Database MeSH Database Single Citation Matcher Batch Citation Matcher ... Cubby Related Resources Order Documents NLM Gateway TOXNET Consumer Health ... PubMed Central Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links HomoloGene Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links Show: Sort Author Journal Pub Date Text File Clipboard E-mail Order Nature. 2002 Jan 10;415(6868):180-3. Related Articles, Links Comment in: Nature. 2002 Jan 10;415(6868):123-4. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, Yang L, Wolting C, Donaldson I, Schandorff S, Shewnarane J, Vo M, Taggart J, Goudreault M, Muskat B, Alfarano C, Dewar D, Lin Z, Michalickova K, Willems AR, Sassi H, Nielsen PA, Rasmussen KJ, Andersen JR, Johansen LE, Hansen LH, Jespersen H, Podtelejnikov A, Nielsen E, Crawford J, Poulsen V, Sorensen BD, Matthiesen J, Hendrickson RC, Gleeson F, Pawson T, Moran MF, Durocher D, Mann M, Hogue CW, Figeys D, Tyers M.

82. Global Response Of Saccharomyces Cerevisiae To An Alkylating Agent Global Response of saccharomyces cerevisiae to an Alkylating Agent.Scott A. Jelinsky and Leona D. Samson* Department of Cancer Cell http://www.hsph.harvard.edu/geneexpression/index_1.html

Global Response of Saccharomyces cerevisiae to an Alkylating Agent Scott A. Jelinsky and Leona D. Samson Department of Cancer Cell Biology Division of Toxicology Harvard School of Public Health 665 Huntington Ave. Boston, MA 02115 USA PNAS 1999 96 (4): p. 1486-1491 ABSTRACT DNA chip technology allows one to simultaneously examine how ~6,200 Saccharomyces cerevisiae gene transcript levels, representing the entire genome, respond to environmental change. Using chips bearing oligonucleotide arrays we show that ~325 gene transcript levels are increased, and ~76 are decreased, upon exposure to alkylating agent. Of the 21 genes that were already known to be induced by a DNA damaging agent, 18 can be scored as inducible in this data set, and surprisingly, most of the newly identified inducible genes are even more strongly induced then these. 42 responsive and 8 non-responsive ORFs were examined by conventional Northern blot; 48/50 showed the same response by both methods, with magnitudes displaying a correlation coefficient of 0.79. Responsive genes fall into several expected and many unexpected categories and evidence for the induction of a program to eliminate and replace alkylated proteins is presented. The following contains supplementary data tables to PNAS 1999 96 (4): p. 1486-1491 Table1 and Table 2 contain more comprehensive data than present in the manuscript. The complete data set is also available as a tab delimitated file for downloading:

83. ARS Project: Identification And Performance Of Ethanologenic Saccharomyces Strai Identification and Performance of Ethanologenic saccharomyces Strain for Fermentationof Galactose from Lignocellulosic Hydrolysates (405798)The objective of http://www.ars.usda.gov/research/projects/projects.htm?ACCN_NO=405798

84. Chronic Diarrhea: Saccharomyces Boulardi From Liz Meyer DNC NEWS Honey not sugar saccharomyces boulardi Subject A novelyeast supplement is not only useful for treating chronic diarrhea but may be http://www.annieappleseedproject.org/sacboulchron.html

From Liz Meyer: DNC NEWS: Honey not sugar: Saccharomyces boulardi Subject: A novel yeast supplement is not only useful for treating chronic diarrhea but may be useful at stimulating enzyme production. In the course of my work I hear occasional curious symptoms that I have no treatment for. I file these stories away somewhere in the back corner of my memory. I remember a patient who in passing told me she gets terribly bloated if she eats any sugar but is perfectly fine eating honey. So use honey, I told her, without any better solution to offer. What was going on? Curiously, she probably secreted inadequate amounts of disaccharidases. These enzymes cleave apart the two sugar molecules in white sugar to form glucose and fructose. Bees add these enzymes to flower nectar (which is really just perfumed sugar syrup) and predigest the sucrose into glucose and fructose. This patient couldnt break apart the double sugar molecules in white sugar so she couldnt absorb these sugars into her bloodstream. Instead any sugar she ate went through her small intestine untouched into her large intestine where it was fermented by the bacteria and yeast that live there. Fermentation releases a huge amount of gas. She wasnt happy about it.

85. PGA/CBI: Bakers Yeast (Yeast) ( Saccharomyces Cerevisiae ) Image of the Western blot for the antibodies to genes from Bakers yeast (Yeast)( I saccharomyces cerevisiae /i ). Return to PGA Core Home Page http://cbi.swmed.edu/computation/pga/west/sp17_Saccharomyces_cerevis/sp17_Saccha

Return to PGA Antibody Core Home Page Antibodies to Genes from Bakers yeast (Yeast) ( Saccharomyces cerevisiae Link to Details PGA Code(s) View Westerns or Order western fkh2 or ynl068c or n2403 or ynl2403c western Regulates respiratory functions; encodes divergent overlapping tr... western IOC2-C western IOC3-C ... western ORF YOR372c western western western 20S proteasome subunit beta3_sc western western Regulatory Particle Non-ATPase 9 western SNF2-C 2 westerns western ... western ORF YKL112w western western ORF YKL011c western western western ORF YBR114w western ORF YER162C Program for Genomic Applications PGA Antibody Core at the Center for Biomedical Inventions, University of Texas Southwestern Medical School. Ross Chambers, primary investigator Xiao-Hua Li, head of antibody production Preston Hunter, bioinformatics support

86. Cell Cycle Lab The yeast saccharomyces cerevisiae. Starfish oocytes; Mammalian celllines; Sea urchin eggs; saccharomyces cerevisiae; Plasmodium falciparum. http://www.sb-roscoff.fr/CyCell/Page44.htm

The yeast Saccharomyces cerevisiae Starfish oocytes Mammalian cell lines Sea urchin eggs Saccharomyces cerevisiae Plasmodium falciparum

87. WD-repeat Proteins In The Saccharomyces Cerevisiae Genome Bmerc Logo WDrepeat proteins in the saccharomyces cerevisiae genome.(click on the number of repeats to view alignment). YBL008W http://bmerc-www.bu.edu/wdrepeat/yeast.html

WD-repeat proteins in the Saccharomyces cerevisiae genome (click on the number of repeats to view alignment) 6 repeats , HIR1 protein 6 repeats ) probable membrane protein 6 repeats , probable GTP-binding protein 5 repeats , MSI1 protein 5 repeats , TATA box-binding protein-associated factor chain TAFII90 5 repeats ) hypothetical protein 5 repeats ) hypothetical protein 4 repeats ) hypothetical protein 6 repeats , hypothetical protein 8 repeats , hypothetical protein 7 repeats , regulatory protein TUP1 6 repeats , coatomer complex alpha chain RET1 6 repeats , WEB1 protein 5 repeats ) hypothetical protein 6 repeats , PAS7 protein 6 repeats , hypothetical protein 7 repeats , CDC40 protein 5 repeats ) hypothetical protein 4 repeats ) hypothetical protein 7 repeats , cell division control protein CDC4 similar to: (fragment) 6 repeats , hypothetical protein 4 repeats ) hypothetical protein 5 repeats ) SEC13 protein homolog 7 repeats , cell division control protein CDC20 6 repeats , coatomer complex beta' chain 5 repeats , antiviral protein SKI8 8 repeats , probable membrane protein 4 repeats ) hypothetical protein 8 repeats , MET30 protein 5 repeats ) hypothetical protein 4 repeats , MAK11 protein 6 repeats , DOA1 protein 6 repeats , hypothetical protein similar to: 6 repeats , SOF1 protein 10 repeats , DIP2 protein 6 repeats , SEC13 protein 8 repeats , probable membrane protein 8 repeats ) probable membrane protein 5 repeats , hypothetical protein 5 repeats ) hypothetical protein 6 repeats , AIP1 protein 4 repeats ) hypothetical protein 6 repeats ) hypothetical protein

88. DSMZ - Saccharomyces Cerevisiae Translate this page DSMZ - List of Microbial Species saccharomyces cerevisiae (Yeasts), Name, saccharomycescerevisiae Meyen ex EC Hansen see also S. bayanus, S. pastorianus. http://www.dsmz.de/species/sp301144.htm

DSMZ - List of Microbial Species: Saccharomyces cerevisiae (Yeasts) Name Saccharomyces cerevisiae Meyen ex E.C. Hansen see also S. bayanus S. pastorianus Strains , listed under other name: DSMZ Microorganisms

89. DSMZ - Saccharomyces saccharomyces bailii; saccharomyces bayanus; saccharomyces bisporus; http://www.dsmz.de/species/gn301138.htm

DSMZ - List of Microbial Genera: Saccharomyces (Yeasts) List of Species Saccharomyces aceti Saccharomyces bailii Saccharomyces bayanus Saccharomyces bisporus ... Microorganisms

90. Saccharomyces Cluster Analysis Server http://bioinfo.mbb.yale.edu/genome/yeast/cluster/

91. The National Collection Of Yeast Cultures Catalogue Strains Saccharomyces Dairen The National Collection of Yeast Cultures catalogue strains saccharomyces dairenensisto saccharomyces willianus. saccharomyces dairenensis Naganishi. 777. http://www.ifr.bbsrc.ac.uk/ncyc/CATSdSw.html

Saccharomyces dairenensis Naganishi. . I.Campbell (1974). CBS 421, NRRL Y-1353, ATCC 10597, IFO 1168. T; from dry fruit of Diospyros sp. (persimmon). . T.F.Brocklehurst (1983). E3. From spoiled coleslaw. (Brocklehurst et al. 1983) Max. temp. 31C, min. temp. 11C, optimum temp. 28C . T.F.Brocklehurst (1983). Y2-80. From shredded cabbage. (Brocklehurst et al. 1983) Max. temp. 31C, min. temp. 8C, optimum temp. 29C . T.F.Brocklehurst (1986). Candida humilis. From potato salad. Saccharomyces diastaticus Saccharomyces elegans Saccharomyces ellipsoideus Reess. See Saccharomyces cerevisiae Saccharomyces eupagycus (Sacchetti ex Kudryavtsev) van der Walt. See Zygosaccharomyces florentinus Saccharomyces exiguus Reess. Sexual state of Candida holmii . I.Campbell (1974). ATCC 10599, CBS 379, CCRC 21524, CECT 11192, DBVPG 6252, IFO 1128, JCM 1790, NRRL Y-1538, NRRL Y-12640 T; from Institute of Brewing Tokyo. . J.Atputharajah (1979). CRI 22. From toddy. . T.F.Brocklehurst (1983). O11. From spoiled coleslaw. (Brocklehurst et al. 1983) Max. temp. 33C, min. temp. 11C, optimum temp. 28C . DBVPG (1998). ATCC 10670, CBS 134, CCRC 22072, DBVPG 6413, IFO 0660, NRRL Y-1507, NRRL Y-12692, NRRL Y-17030. (Reess 1870).

92. NCYC Catalogue - Saccharomyces Cerevisiae The National Collection of Yeast Cultures catalogue strains of saccharomycescerevisiae. saccharomyces cerevisiae. saccharomyces http://www.ifr.bbsrc.ac.uk/ncyc/CATScerevisiae.html

Saccharomyces cerevisiae Saccharomyces cerevisiae Ale strains Saccharomyces cerevisiae Lager, Distilling, Wine and Cider strains Saccharomyces cerevisiae Mutant strains General Strains Saccharomyces cerevisiae Hansen . CBS (1957). CBS 1171, ATCC 18824. Type strain for Saccharomyces cerevisiae. From brewing yeast. 5:1:5:5:1 . A.C.Chapman (1933). Saccharomyces anamensis. NCTC 3864. . Schmitt (1924). Saccharomyces brasiliensis. 98 Carlsberg strain, NCTC 1808. . ATCC (1945). Saccharomyces carlsbergensis. ATCC 9080, ATCC 24904, CBS 2354. Assay of inositol, pantothenic acid and pyridoxin; maltose fermentation studies (Mol.Gen.Genet., 1972, 115, 80-88); alpha-glucosidase synthesis (Biochem. Biophys. Acta 1973, 294, 517-526); 2micron plasmid negative (J.Inst.Brew., 1980, 86, 78-80; Genetics, 1977, 86, 73); Produces ergosterol (Biochem. Biophys. Res. Commun., 1981, 103, 272-277). . A.C.Chapman (1933). Saccharomyces cartilaginosus. NCTC 3865. . A.Harden (1921). Baker's yeast strain. Requires thiamin, pantothenate and biotin (Arch.Biochem., 1947, 14, 369. J.Gen.Microbiol., 1983, 128, 2615-2620). . A.C.Chapman (1925). NCTC 2160 . H.B.Hutchinson (1930). GB 354, NCTC 5922.

93. Untitled saccharomyces cerevisiae. saccharomyces cerevisiae is used commerciallyfor baking, brewing, wine making and distilling. For several http://www.abdn.ac.uk/~gen069/saccharomyces.htm

Al Brown's Web Site Welcome The Lab New Positions Candida ... Hot Links Al Brown's Web Site Welcome The Lab New Positions Candida ... Hot Links Saccharomyces cerevisiae Saccharomyces cerevisiae is used commercially for baking, brewing, wine making and distilling. For several reasons this yeast is the pre-eminent model organism for studies of fundamental aspects of eukaryotic cell biology (see Hot Links S. cerevisiae Budding yeast cells We are interested in how S. cerevisiae changes its patterns of gene expression in response to environmental change. One approach has been to study the post-transcriptional regulation of the gluconeogenic genes, and in response to glucose. Responses to glucose are important in S. cerevisiae because they control the switch from fermentative to respiratory metabolism in this yeast, as well as the alternative metabolic pathways of carbon assimilation. In collaboration with Juana-Maria Gancedo's group, we found that glucose Glucose signalling and mRNA turnover represses the transcription of the and genes and accelerates the degradation of these mRNAs. Interestingly, very small amounts of glucose are sufficient to trigger these responses (0.01% glucose) indicating that yeast is more sensitive to glucose than had previously been realised. We are now dissecting the signal transduction pathways that mediate these responses to low levels of glucose, and the mechanisms by which the gluconeogenic mRNAs are degraded (see

94. A PROMOTER DATABASE OF YEAST SACCHAROMYCES CEREVISIAE (SCPD) A PROMOTER DATABASE OF YEAST saccharomyces CEREVISIAE (SCPD). About 6000 opening readingframes have been annotated in the genome of saccharomyces cerevisiae. http://www.bionet.nsc.ru/bgrs/thesis/1/

A PROMOTER DATABASE OF YEAST SACCHAROMYCES CEREVISIAE (SCPD). JIAN ZHU ZHANG MICHAEL Q. Cold Spring Harbor Laboratory, P. O. Box 100, 1 Bungtown Road, Cold Spring Harbor, NY 11724, U. S. A.; mzhang@cshl.org Keywords : promoter, database, yeast, genes, regulatory regions, transcription factors, analysis tools 1. Introduction About 6000 opening reading frames have been annotated in the genome of Saccharomyces cerevisiae . Among these, about 3000 genes have been identified and studied by various means. In most cases, the gene expression is regulated by upstream regulatory elements, which are the binding sites of transcriptional factors. Roughly 150 genes code for transcriptional factors. Some of them have been shown to bind to specific sites on DNA, either activate or repress transcription via contact with basal transcription machinery. Some factors are universal which control the basal level of transcription. Others are specific to a group of coregulated genes or response to specific signals. Efforts have been made to construct databases containing the information of promoter regions EPD (1), transcriptional factors, TRANSFAC(2) and TFD(3), and transcriptional regulatory regions, TRRD(2). Here we present an integrated promoter database of the yeast

95. The Curie Institute - Dna Repair And Cell Cycle In Saccharomyces Cerevisiae Dna repair and cell cycle in saccharomyces cerevisiae. Group leader Gérard Faye. Physicalinteraction of Cdc28 with Cdc37 in saccharomyces cerevisiae. Mol. http://www.curie.fr/recherche/themes/detail_equipe.cfm/lang/_gb/id_equipe/48.htm

Search Back to home Scientific activities Research units ... Genotoxicology and cell cycle - UMR 2027 CNRS/IC Dna repair and cell cycle in saccharomyces cerevisiae Group leader : Gérard Faye Group and history Publications Meeting participation Phd and master ... to Unit page I - Ssu72 and transcription termination One can distinguish three stages in the transcription of RNA by RNA polymerase II: (1) the transcription initiation with (i) the recognition of the promoter, (ii) the formation of the pre-initiation complex, (iii) the initiation of the RNA synthesis, then (iv) the release of RNA polymerase II from the promoter; (2) The elongation; (3) the transcription termination and the dissociation of RNA polymerase II from the template. During the transcription process, most pre-mRNA produced by RNA polymerase II are matured by 5' capping, splicing and 3' cleavage and poly(A) addition. After these last two steps RNA polymerase II pauses and leaves the DNA template. A systematic analysis of yeast protein complexes revealed that protein Ssu72 is present in the cleavage/polyadenylation complex, which is composed of about twenty proteins. Ssu72 has also been found interacting with TFIIB and Taf150 that play a role in transcription initiation, and with Rpb2, the second-largest subunit of RNA polymerase II. Ssu72 is an evolutionarily conserved protein, present only in eukaryotes. We have shown that Ssu72 is a phosphatase that functionally interacts with the CTD kinase Kin28 and the Paf1/Ctr9 elongation complex, and genetically interacts with the CTD phosphatase Fcp1. A genome-wide expression analysis of mutant

96. Institut Curie - Réparation Et Cycle Cellulaire Chez Saccharomyces Cerevisiae Translate this page Réparation et cycle cellulaire chez saccharomyces cerevisiae. Physical interactionof Cdc28 with Cdc37 in saccharomyces cerevisiae. Mol. Gen. http://www.curie.fr/recherche/themes/detail_equipe.cfm/lang/_fr/id_equipe/48.htm

Rechercher Retour Activités scientifiques Les responsables de recherche Les plateformes technologiques ... Génotoxicologie et cycle cellulaire - UMR 2027 CNRS/IC Réparation et cycle cellulaire chez saccharomyces cerevisiae Publications Partenariats, collaborations et soutiens Contacts I - Ssu72 et la terminaison de la transcription II - Cak1, le cycle cellulaire et la transcription Saccharomyces cerevisiae III - Inhibiteurs de CDK humaines Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast. EMBO J., 22(7):1588-98 abstract Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1 and Tfb3. J. Biol. Chem., 277: 10852-10860 abstract Physical interaction of Cdc28 with Cdc37 in Saccharomyces cerevisiae. Mol. Gen. Genomics, 267: 447-458 abstract Xbp1-mediated repression of clb gene expression contributes to the modifications of yeast cell morphology and cell cycle seen during nitrogen-limited growth. Mol. Cell. Biol., 21: 3714-3724 abstract Disruption and functional analysis of six ORFs on chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1). Yeast, 18, 273-282

97. Nikon MicroscopyU: Phase Contrast Image Gallery - Saccharomyces Yeast Cells saccharomyces cerevisae is an exceptionally important yeast. It is PhaseContrast Image Gallery. saccharomyces Yeast Cells. Members of http://www.microscopyu.com/galleries/phasecontrast/saccharomycessmall.html

Small World Contest Interactive Tutorials Basic Concepts Microscope Optics ... MicroscopyU Home Phase Contrast Image Gallery Saccharomyces Yeast Cells Members of the Saccharomyces genus of yeast fungi have a direct impact on the daily lives of society. Whenever a dinner roll is nibbled or a glass of wine sipped these microorganisms are largely responsible. One of Saccharomyces' many species is employed primarily for the fermentation of sugars in the winemaking process, while another is useful for the rising of bread. Positive Phase Contrast Negative Phase Contrast The genus Saccharomyces is similar to other yeast genera. Its species are unicellular and cylindrical, oval, or spherical in shape. They reproduce asexually through a process of budding, a new cell forming a protrusion on an existing cell, enlarging, and then breaking away. They can also reproduce sexually through the use of spores. In fact, the Saccharomyces genus is distinguished by asci , small internal structures that contain four to eight sexually produced fungal spores. All yeasts flourish in the presence of sugars and obtain food by direct absorption of nutrients. Saccharomyces cerevisae is an exceptionally important yeast. It is the organism commonly referred to as

98. Information About Species In The EF-Hand Calcium-Binding Proteins Database SCALLOP, bay scallop, Aequipecten irradians, AEQIR, n, n, n, y, SCEREV, bakersyeast, saccharomyces cerevisiae, YEAST, n, n, n, y, SCHDU, Scherffelia dubia,SCHDU, n, y, n, y, http://structbio.vanderbilt.edu/cabp_database/seq/species.html

Information about Species in the EF-Hand Calcium-Binding Proteins Database Species are listed by the code used to identify them in interspecies sequence alignments. Code Common Name Scientific Name SWISS-PROT Code Mammal Plant Vertebrate Eukaryote Comment ACHLY Achlya klebsiana ACHKL n n n y ALFALFA alfalfa Medicago sativa MEDSA n y n y AMPHIFL Florida lancelet Branchiostoma floridae BRAFL n n n y AMPHIOX amphioxus or common lancelet Branchiostoma lanceolatum BRALA n n n y AMPHIUMA salamander Amphiuma means AMPME n n y y APPLE apple Malus domestica MALDO n y n y ARABID mouse-ear cress Arabidopsis thaliana ARATH n y n y This plant is commonly used for genetic studies ATRIP Atriplex nummularia ATRNU n y n y BALTCOD Baltic cod Gadus callarias GADCA n n y y BARLEY barley Hordeum vulgare HORVU n y n y BARNACLE giant barnacle Balanus nubilis BALNU n n n y BEECHNUT beechnut Fagus sylvatica FAGSY n y n y BLFLUKE blood fluke Schistosoma mansoni SCHMA n n n y BOA Boa constrictor Boa constrictor BOACO n n y y BOVINE cow or bovine Bos taurus BOVIN y n y y CANDIDA yeast Candida albicans CANAL n n n y CAPAN bell pepper Capsicum annum CAPAN n y n y CARP carp Cyprinus carpio CYPCA n n y y CARROT carrot Daucus carota DAUCA n y n y CELEG roundworm Caenorhabditis elegans CAEEL n n n y This worm is commonly used in genetic studies CHICK chicken Gallus gallus CHICK n n y y CHINHAM Chinese hamster Cricetulus griseus CRIGR y n y y CHLAMY green algae Chlamydomonas reinhardtii CHLRE n y n y CHLNI akazara scallop Chlamys nipponensis akazar CHLNI n n n y CRAY narrow-fingered crayfish Pontastacus leptodactylus PONLE n n n y DICTY slime mold Dictyostelium discoideum DICDI n n n y DROPS fruit fly Drosophila pseudoobscura

99. Cellml.org - Glycolysis Metabolic Pathway In Saccharomyces Cerevisiae Glycolysis Metabolic Pathway in saccharomyces cerevisiae. PDFPDF. In VivoAnalysis of Metabolic Dynamics in saccharomyces cerevisiaeII. http://www.cellml.org/examples/repository/glycolysis_pathway_1997_doc.html

HOME REPOSITORY DEVELOPER the CellML site IUPS Physiome Project Model Repository Search the Repository Signal Transduction Metabolic Pathway Cardiac Electrophys. ... Model Downloads Glycolysis Metabolic Pathway in Saccharomyces cerevisiae PDF Author:           Catherine Lloyd (Bioengineering Institute, University of Auckland) Table of Contents Model Structure Download This Model Model Structure Metabolic networks are highly complex nonlinear reaction systems whose functions are tightly co-ordinated and regulated by feedback mechanisms to meet the physiological demands of living organisms. Dynamic mathematical models of metabolic networks allow prediction as to how metabolism will respond to manipulation. In 1997, Manfred Rizzi, Michael Baltes, Uwe Theobald and Matthias Reuss published a kinetic model of glycolysis in the yeast Saccharomyces cerevisiae (see Figure 1 below). The model is based on rate equations for the individual reactions of the glycolysis pathway, and it aims to predict changes in the concentrations of intra- and extracellular metabolites after a glucose pulse. The model structure and experimental observations are related to the aerobic growth of yeast. The kinetic equations for the various enzyme-catalysed reactions have been taken from the results of several previous studies carried out by other researchers. The reactions are diverse in nature and they include Hill kinetics, Michaelis-Menten kinetics, allosteric regulation, competitive inhibition, substrate inhibition, activation, reversible and irreversible reactions.

100. Saccharomyces Genomic Resources Stanford Genomic Resources The Stanford Genomic Resources encompases boththe saccharomyces Genome Database and the Arabidopsis thaliana Database. http://biotech.icmb.utexas.edu/pages/science/yeast.html

Yeast Genomic Resources Stanford Genomic Resources The Stanford Genomic Resources encompases both the Saccharomyces Genome Database and the Arabidopsis thaliana Database. The SGD project collects information for and maintains a database of the yeast Saccharomyces cerevisiae, commonly known as baker's or budding yeast. This database includes a variety of genomic and biological information including a gene registry and database. The AAtDB project also has a database as well as a number of images and data tables. About BioTech Home BioTech Dictionary BioTech Resources ... Tour Last updated: July 23, 1998 URL: http://biotech.icmb.utexas.edu/pages/science/yeast.html Questions or Comments: feedback@biotech.icmb.utexas.edu BioTech Resources Web Project Indiana Institute for Molecular and Cellular Biology , 1995-1998 The Trustees of Indiana University

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