141. Japan Society Of Gene Therapy Facilitates interdisciplinary gene therapy research between investigators performing basic and applied research and clinical trials through academic conferences, international symposia and publications. http://bizweb.justnet.ne.jp/~jsgt/

THE 10TH ANNUAL MEETING Last Update : May 17, 2004 Peace on Earth May the New Year bring you prosperity and joy ! Many thanks and Welcome ! Although many cancelled visits to the 9th Annual Meeting due to SARS, the meeting was able to be held in great success. We would like to express our greatest gratitude to the attendees who participated and made the meeting so beneficial under such difficult circumstances. Now, we are planning on a new exciting program. In addition to the usual annual meeting of JSGT, we are arranging a joint symposium with Molecular Biology of Hematopoiesis (MBH). We are expecting a great many of your participation in the 10th Annual Meeting of JSGT-2004, and looking forward to seeing you again in Tokyo. New Information from the Journal of Gene Medicine Comment on Emergency Report "Reports of second serious adverse event in a clinical trial of gene therapy for X-linked severe combined immune deficiency(X-SCID)" JSGT-Comment(Japanese) Up-To-Date(Jap) ! Click! ESGT-Press release JSGT-Web Links Click !

142. National Human Genome Research Institute - Talking Glossary Of Genetic Terms explained Listen to a detailed explanation. Dr. Michael Blaese defines gene therapy. related terms cDNA library, gene, genome, inherited, protein. http://www.genome.gov/glossary.cfm?key=gene therapy

143. Cell Transplants International Notfor-profit medical research foundation working to find a treatment for muscular dystrophy and other genetic diseases through cell/gene therapy. Site describes treatments and clinical trials. http://www.celltherapy.com/

Home What's New Dr. Law's Response to His Critics Myoblast vs. Stem Cells ... Contact Us Established in 1997, Cell Transplants International, LLC (CTI) is dedicated to finding treatments for muscular dystrophy, heart, type II diabetes, and other hereditary degenerative diseases. Our current work focuses on heart angiomyogenesis using myoblasts. CTI's pioneering work has developed over the past 33 years and is the first research into human cell/gene therapy. It is the only human genome therapy in existence. Extensive experience in large-scale production of pure myoblasts and intellectual property portfolio encompassing the production and use of myoblasts give CTI a unique advantage over its competitors. Be sure to visit the What's New section to read about our latest development in heart treatment. Click here to visit the Human Genome Therapy Research website

144. The Physician And Sportsmedicine: Gene Therapy And Tissue Engineering In Sports gene therapy and Tissue Engineering in Sports Medicine. Vladimir Martinek, MD; Freddie H. Fu, MD; Johnny Huard, PhD. gene therapy. http://www.physsportsmed.com/issues/2000/02_00/huard.htm

Gene Therapy and Tissue Engineering in Sports Medicine Vladimir Martinek, MD; Freddie H. Fu, MD; Johnny Huard, PhD THE PHYSICIAN AND SPORTSMEDICINE - VOL 28 - NO. 2 - FEBRUARY 2000 In Brief: Treatment of sports injuries has improved through sophisticated rehabilitation programs, novel operative techniques, and advances in biomechanical research during the past two decades. Despite considerable progress, treatments remain limited due to poor healing capacity for anterior or posterior cruciate ligament rupture, central meniscal tear, cartilage lesions, and delayed bone fracture. New biological approaches seek to treat these injuries with growth factors to stimulate and hasten the healing process. Gene therapy using the transfer of defined genes such as those encoding growth factors represents a promising way to deliver therapeutic proteins to the injured tissue. Tissue engineering, which may eventually be combined with gene therapy, offers the potential to create tissues or scaffolds for regeneration of defects occurring from trauma. T he treatment of sports-related injuries has improved continuously during the last two decades. New, minimally invasive operative techniques, especially arthroscopy, novel instruments, modern rehabilitation and medications, as well as increasing knowledge of joint biomechanics and trauma pathophysiology, have enhanced and accelerated therapy. Despite this progress, deficits in injury treatment remain because of the limited healing capacity of certain musculoskeletal system tissues. Ligaments, tendons, menisci, and articular cartilage have a limited blood supply and a slow cell turnover. For this reason, healing is prolonged and often results in the formation of a dysfunctional scar or a tissue defect.

145. Gene Therapy Advisory Committee - GTAC Advises on the ethical acceptability of proposals for gene therapy research on humans taking account of the scientific merits and the potential benefits and risks, and provides advice to UK Health Ministers on developments in gene therapy research. http://www.doh.gov.uk/genetics/gtac

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146. Gene Therapy gene therapy. Mill Hill essays 1995 gene therapy Simple in theory but difficult in practice. An essay on gene therapy, published http://omni.ac.uk/browse/mesh/detail/C0017296L0017296.html

low graphics Gene Therapy broader: Genetic Engineering other: Blood Transfusion Immunotherapy Sex Preselection GeneMed network GeneMed Network is a searchable information service that provides up-to-date news and information relating to gene therapy for the public and professionals. The site provides a bulletin board, news, journal articles, scientific information, general information, consulting reports, clinical trials, technical monitoring, and institutes and companies. Genetics, Medical Gene Therapy Mill Hill essays 1995 : Gene therapy : Simple in theory but difficult in practice An essay on gene therapy, published by the National Institute for Medical Research as part of the Mill Hill Essays, 1995. The essays cover topical subjects and are aimed at increasing the understanding of medical sciences amongst the general public. Popular Works [Publication Type] Gene Therapy Gene Therapy Advisory Committee : GTAC The Gene Therapy Advisory Committee (GTAC) was established in 1993, as a result of a key recommendation of the Committee on the Ethics of Gene Therapy (CEGT). This non-statutory body aims to oversee gene therapy research in the UK and provides advice to UK health Ministers on developments in gene therapy research. This Web site contains a listing of members of GTAC, minutes of GTAC meetings, annual reports, and publications from the GTAC working parties. Most of the documentation is in PDF, which requires Adobe Acrobat Reader. Published on the Web by the Department of Health (DH).

147. Gene Therapy And Genomics gene therapy and Genomics, Home . Earth Science. , Alternative Energy. Endangered Species. gene therapy. Genetically Modified Food. Stem Cell Research. http://www.brightsurf.com/l_gene_therapy.html

[ Home ] Earth Science Alternative Energy Anthropology and Archaeology Earthquakes and Volcanoes Environment and Nature News ... Tsunami Space Science Astronomy and Space News Black Holes Chandra X-Ray Observatory Extrasolar Planets ... Space Weather Life Science Animal News Biotechnology and Genetics Brain Research Human Cloning ... Whales and Whaling Gene Therapy and Genomics Gene Therapy Clinical Trials - find out what countries trials are underways in, what diseases are being addresses by therapy, and more. From the Journal of Gene Medicine. What is Gene Therapy? - overview from Jim Wilson of the University of Pennsylvania's Institute for Human Gene Therapy . Introduction Jim Wilson What is Gene Gene therapy offers hope for anaemia sufferers Genetic Testing and Gene Therapy: What They Mean To You and Your Family - questions and answers from Ask NOAH. In the Service of Science - report on alleged regulatory and monitoring shortcomings over gene therapy trials in the U.S. and Canada. From CBC News' The Magazine. Introduction to Gene Therapy - primer on the subject, originally designed to supplement a course taught at Vanderbilt University.

148. Department Of Surgery, University Of Liverpool Research focusing on treatment of pancreatic cancer and acute pancreatitis using gene therapy and surgical techniques, from the Department of Surgery. http://www.liv.ac.uk/surgery/resrch.html

Department of Surgery Department Home Page Staff Research EUROPAC ... University home page RESEARCH The Department of Surgery has an extremely active research profile. Please click on a topic to find out more: Feedback: greenhaf@liv.ac.uk Last reviewed 22/1/2001.

149. CNN.com - Gene Therapy For Parkinson's Disease Begins - Aug. 19, 2003 Researchers slipped billions of copies of a gene into the brain of a Parkinson s disease patient Monday, marking the first attempt to test gene therapy in a http://www.cnn.com/2003/HEALTH/conditions/08/19/gene.therapy.ap/

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Gene therapy for Parkinson's disease begins Story Tools RELATED Painkillers may cut Parkinson's risk HEALTH LIBRARY Health Library What is Parkinson's disease? NEW YORK (AP) Researchers slipped billions of copies of a gene into the brain of a Parkinson's disease patient Monday, marking the first attempt to test gene therapy in a person with that disease. The patient, 55-year-old Nathan Klein of Port Washington, New York, said he was "feeling fine" in a telephone interview a few hours after the surgery. Klein said the disease gave him a tremor in his right arm, and made him shuffle and have to catch himself sometimes from falling. Medicines offer some relief, he said, but when he heard about the new study he decided to volunteer. With the disease, "you don't want to go out," Klein said. "It's embarrassing when you're shaking a lot and you walk like an old man." Klein is the first of a planned 12 patients for the study, said the surgeon, Dr. Michael Kaplitt of Weill Cornell Medical College. The research is focused on the procedure's safety, rather than whether or not it relieves symptoms. "Our whole goal here is to prove this is safe before we move on," Kaplitt said.

150. Research At MCRI The CAGT group of MCRI focuses on gene therapy research for neurological, haematological and liver diseases affecting babies, children and adolescents. http://murdoch.rch.unimelb.edu.au/pages/research/research.asp?P=oview&G=10&a

151. CNN.com - The Fall And Rise Of Gene Therapy - May 8, 2000 The fall and rise of gene therapy. by gene therapy has been long promised as a way to treat the kind of defect that causes SCID. But http://www.cnn.com/2000/HEALTH/05/08/ethics.matters/

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: The fall and rise of gene therapy by Jeffrey P. Kahn, Ph.D., M.P.H. Director, Center for Bioethics University of Minnesota May 8, 2000 Web posted at: 4:31 p.m. EDT (2031 GMT)

152. SCOPE NOTE SERIES Essays on genetic screening, eugenics and gene therapy, from National Reference Center for Bioethics Literature, Georgetown University, Washington, DC. http://www.georgetown.edu/research/nrcbl/scopenotes/

Scope Note Series Search Request Form on the Library's web site or calling the NRC . Please note that, as of SCOPE NOTE 15, the series appears in the Kennedy Institute of Ethics Journal (KIEJ). For those researchers associated with institutional libraries subscribing to Johns Hopkins University's Project Muse, Scope Notes 30 to date are available full-text, online at the Project Muse web site. Further information about Project Muse is also available at that site. The series continues to be published separately as reprints. Price: $5.00/issue; $8.00/issue overseas. Order from: Scope Notes, Kennedy Institute of Ethics, Box 571212, Georgetown University, Washington, DC 20057-1212; Telephone: 800-MED-ETHX (toll-free) or 202-687-3885; FAX 202-687-6770; e-mail: bioethics@georgetown.edu. Dangerousness: Prediction and Legal Status. September 1982. 5 p. Living Wills and Durable Powers of Attorney. Revised April 1992. 19 p. Ethics Committees in Hospitals. KIEJ. Reprinted September 1992. 17 p. Diagnosis Related Groups (DRGs).

153. FAQs On Gene Therapy FAQs on gene therapy. FAQs brought to you by Access Excellence CF gene therapy FAQ. DMD Research Center FAQs on Dystrophin gene therapy (Delivery) Research. http://www.genemed.org/faqs.html

154. The Body: Gene Therapy For HIV/AIDS Topics about gene therapy for HIV/AIDS, at The Body, the complete AIDS and HIV information resource. The Body The HIV/AIDS Authority. gene therapy for HIV/AIDS, http://www.thebody.com/treat/genether.html

Gene Therapy for HIV/AIDS Gene Therapy: The Ultimate Fusion Blocker? (December 2003) A recap of recent research on C36, an artificial gene that produces a peptide that acts similarly to T-20 In GMHC Treatment Issues , from Gay Men's Health Crisis Interfering With RNA: Kill the Messenger (October 2003) In PI Perspective , from Project Inform Researchers Discover Gene in HIV Used to Undermine Immune System (August 25, 2003) In Kaiser Daily HIV/AIDS Report , from Henry J. Kaiser Family Foundation Mimicked Gene Defect Affords HIV Protection (March 14, 2003) In The Prevention News Update , from Centers for Disease Control and Prevention Evaluation of Correlates of Protection in HIV-1 Infected Individuals Spontaneously Controlling Plasma Viral Load in the Absence of Antiretroviral Therapy (October 26, 2002) From The Body's Coverage of the 40th Annual Meeting of the Infectious Diseases Society of America New Strategy, "RNA Interference," Proposed for Fighting HIV (October 25, 2002) In The Prevention News Update , from Centers for Disease Control and Prevention Researchers Develop HIV Fighter in RNA (June 4, 2002)

155. Vaccines-home Vaccines may cause Sudden Infant Death Syndrome (SIDS). The biblical case against vaccines, toxic ingredients in vaccines, questions on what to ask your peditrician, gene therapy by vaccination, and vaccine package inserts information. http://poisonevercure.150m.com/

contact letters and or questions from you other comments HOME ... total body cleanse Before you have your baby Vitamin K ARIZONA STATUTORY LAWS all state laws and exemptions The toxic ingredients causing adverse reactions Have you or your child been injured due to the vaccine(s) received? Nine year old gets $4.7 million for vaccine injuries drugs companies lobby to stop aid for vaccine injuries ... package inserts Vaccines linked to diseases: diabetes multiple sclerosis E. coli infections vaccine manufacturers ... U.S. national charts Video I nternational Academy of Oral Medicine and Toxicology Video: mercury beyond blood/brain barrier video WLTV 12 - Jacksonville, FL Report by Melissa Ross video: WFAA-TV Dallas, Texas Report by Valeri Williams peer review Eli Lilly's safety data sheet WHO explains why mercury shouldn't be removed from vaccines ... Focus on The Family corresponds Chat live to have your questions answered or simply discuss the vaccination issue. Download MIRC chat for free, install and join the "vaccinations" channel

156. Predicted Hazard Of Gene Therapy A Reality ISIS was almost a lone voice warning of cancer from foreign genes inserting into the genome in ‘gene therapy’ and other exposures to transgenic DNA. http://www.i-sis.org.uk/PHGT.php

HOME BIOTECHNOLOGY SCIENCE of the ORGANISM SCIENCE in SOCIETY ... PUBLICATIONS Search the ISIS website ISIS Members Area Login [ membership details USERNAME PASSWORD Predicted Hazard of Gene Therapy A Reality Dr. Mae-Wan Ho calls for a comprehensive review of gene therapy and other transgenic technologies, for they carry similar risks. The French team that made news in 2000 treating children with severe combined immune deficiency (SCID) had to call a halt to the gene therapy trial. One of the ten children treated has developed what looks like leukaemia. SCID is attributed to a mutation in a gene on the X-chromosome. Alain Fischer and Marina Cavezzena-Calvo at the Necker Hospital in Paris pioneered the ex vivo procedure, in which bone marrow cells taken from the patient are transformed outside the body, using a vector carrying a normal copy of the mutated gene to insert the gene into the genome. The transgenic cells are then re-introduced into the patient. This was hailed as a breakthrough for gene therapy, as it avoided most of the risks of

157. What Is Gene Therapy? What is gene therapy? http://www.biotech.wisc.edu/Education/Poster/genetherapy.html

What is gene Therapy? Biotechnology Outreach Home SEE Biotech Some human diseases are caused by a defective gene. An example is cystic fibrosis , a disease of mucous glands throughout the body that usually develops during childhood and makes breathing increasingly difficult. IF a child receives two copies of the defective gene call the CF gene one copy from each parent then the child will develop the disease. Biotechnology is used in several ways in detecting, diagnosing and treating cystic fibrosis. Genetic testing or screening enables healthy people to know whether they carry one copy of the CF gene. If both potential parents have one copy each of the CF gene, then the genetic counselor can provide information and help assess whether the couple may have a child who will develop cystic fibrosis. Genetic testing can alert parents their child has two copies of the CF gene, permitting diagnosis even before the disease develops in the child. Children with cystic fibrosis can enjoy some relief from the mucus buildup in their lungs by breathing in a mucus-breaking drug made with recombinant DNA technology. The drug contains a protein that chews up the DNA so the mucus is easier to remove from the lungs by coughing. An experimental approach to curing cystic fibrosis uses a genetically engineered cold virus that delivers to the patient's lung cells a working version of the defective gene. The new gene enables lung cells to make the protein that is lacking in cystic fibrosis patients.

158. Vanderbilt Radiation Oncology Research at a hightechnology treatment facility clinical trials; biological modifiers; therapeutic targets; industry validation of efficacy of pharmaceutical, imaging and radiotherapy methods; medical physics of radiotherapy delivery; radiation-guided drug delivery and gene therapy imaging. Regional facilities. http://www.mc.vanderbilt.edu/radiationoncology

Biological Sciences Medical Physics ... Education Mission Statement The mission of the Department of Radiation Oncology is to improve the treatment outcomes of all diseases treated with radiation and to find new medical uses of radiation. Related to these goals are the education of graduate students, post-doctoral students and residents who will enter the field of radiation medicine including the allied fields of Medical Physics and Radiation Therapy. The Department of Radiation Oncology provides state-of-the-art anti-cancer therapy for patients through the use of new technology and through the continuous review of patient treatment outcome. We will continue to evaluate and improve the therapeutic effects of radiation from five fronts: 1) Basic science research to indentify new biological modifiers and therapeutic targets. 2) Interaction with industry (pharmaceutical, imaging and radiotherapy) to validate the efficacy of new therapeutic tools. 3) Medical phyiscs research to improve the accuracy, precision and methods of radiotherapy delivery. 4) Clinical research to study the benefits of new therapy treatments in patients 5) Development of new radiotherapy facilities throughout the region to provide the best care for all patients.

159. Gene Therapy Potent Against Advanced Prostate Cancer gene therapy Potent Against Advanced Prostate Cancer. The IL2 is a passenger of sorts, riding in the gene therapy vehicle, Belldegrun said. http://unisci.com/stories/20012/0521011.htm

Home Search Gene Therapy Potent Against Advanced Prostate Cancer Researchers at UCLA's Jonsson Cancer Center have shown for the first time that immunotherapy delivered via gene therapy may prove to be a potent weapon in the fight against locally advanced prostate cancer, according to an article published Sunday (May 20) in the peer-reviewed journal Human Gene Therapy Lead author Dr. Arie Belldegrun, chief of urologic oncology at the Jonsson Cancer Center, said his early phase study suggests that intra-tumoral immunotherapy, in combination with surgery to remove the prostate, represents a new option for treating men with cancer that has spread beyond the boundaries of the prostate. Historically, prostate cancer was believed to be resistant to immunotherapy. Belldegrun said his study proves otherwise. "Based on our earlier studies in the laboratory, which were published in the journal Cancer , we suspected that this approach might work in humans," he said. "We did not know, however, that gene therapy and immunotherapy could be options for patients with locally advanced prostate cancer, a high-risk group to whom we have little to offer right now." The study outlined in the article involves injecting gene-based immunotherapy using an ultrasound guidance system directly into the diseased prostate prior to surgery or after the failure of radiation therapy.

160. IngentaSelect: FullText www3.interscience.wiley.com/cgibin/booktoc/89014601 HUM-MOLGEN journals gene therapy Weekly HUM-MOLGEN - Journals Search, gene therapy Weekly, February, 26 2003, virtual library in human genetics and molecular biology. January 20, 1997. http://www.ingentaselect.com/rpsv/cw/mal/10430342/contp1.htm

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