61. UMHS Center For Gene Therapy The center links basic science, clinical investigation and technology transfer endeavors in the area of gene therapy, while also serving as a resource for information and education. http://www.med.umich.edu/cgt/

University of Michigan Medical System Center for Gene Therapy Search the CGT Website Resources Seminar Series Membership Application Intramural Grant Program ... Search Site Updated 10/21/2003 Mission The Center for Gene Therapy at the University of Michigan Medical Center was created to link basic science, clinical investigation and technology transfer. The Center fosters a multidisciplinary approach to new research as well as collaborative research endeavors in the area of gene therapy; extends the services of existing and newly created research cores to investigators; and serves as a resource for information and education. Scope of Activities To aid medical researchers, we have divided the Center into four programs. Each program offers products and services to aid the medical researcher here at Michigan and elsewhere. The products and services are : Gene Vector Program The Vector Core Laboratory Clinical Trials Program Regulatory Application Assistance Educational Program Administrative Program Cellular Therapy Development Grant Program Background The University of Michigan is an established leader in the field of gene therapy and molecular medicine and has pioneered a number of the most innovative gene therapy techniques to be tested in the United States.

62. Archport Ltd. Home Page Bio-Pharmaceutical Contract Manufacturing Provides contract production and R D services (including animal cell fermentation and downstream processing) to the biopharmaceutical/biotechnology industry, of recombinant proteins. Indepth information on suspension, microcarriers, perfusion, batch fermentation, and gene therapy applications. http://www.archport.ie

63. Human Gene Therapy Publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including humans. Subscription based. http://www.liebertpub.com/hum/

Over 23 Years as the Leading Publishers in the Field of Biotechnology Editorial Board Manuscript Submissions Tables of Contents Full-Text Search ... Single Paper Sales ISSN: 1043-0342 Published Monthly Human Gene Therapy ** Impact Factor of 5.132! ** 2002 ISI Journal of Citation Reports ® You may subscribe below: Select Subscription Rate: -Personal Rates- 2004 Online Only Personal $699.00 2004 Outside USA Print Personal $1,075.00 2004 USA Print Personal $746.00 -Institutional Rates- 2004 Online Only Institutional $1,899.00 2004 Outside USA Print Institutional $2,245.00 2004 USA Print and Online Institutional $2,379.00 2004 USA Print Institutional $1,988.00 Please note subscription orders are entered for the complete volume year. For example, if you are ordering the 2004 volume, you will receive any and all issues published to date for that volume. HUMAN GENE THERAPY LAUNCHES ELECTRONIC MANUSCRIPT SUBMISSION AND PEER REVIEW EFFECTIVE MAY 24, 2004 Full-text of the current issue available FREE online. Click here to view.

64. Harvard Gene Therapy Initiative gene therapy Initiative, Harvard Institute of Human Genetics, Harvard Medical School, Children s Hospital, Boston. Conducts research http://hgti.med.harvard.edu/

Gene Therapy Initiative Harvard Institute of Human Genetics HARVARD MEDICAL SCHOOL Dr. Richard Mulligan, Director The Harvard Gene Therapy Initiative was founded with the objective of promoting the use of gene therapy in both research and therapeutic applications and to conduct research developing new gene delivery vector technologies. Dr. Jeng-Shin Lee Associate Director 77 Avenue Louis Pasteur, HIM-412 Boston, MA 02115-5727 Phone: (617) 432-6465 , Fax: (617) 432-7044 Website liaison: Adam H. Lorch

65. Transgene Discovers and develops gene therapy technologies and products for the treatment of acquired or inherited diseases for which there is no cure or adequate therapy at present. (Nasdaq TRGNY). http://www.transgene.fr/

Immunotherapy to fight cancer Home page Site Map Contact Us Search Corporate Overview History Products Locations ... News Company Profile Product Pipeline Cancer vaccines MVA-MUC1-IL2 : Phase II MVA-HPV-IL2 : Phase II Immune enhancement Ad-IL2 : Phase I/II Phase I/II Other programs Preclinical Production Since 1995, Transgene operates its own multi-use, multi-product manufacturing News Press Releases May 12, 2004 Transgene to present data at 2004 ASCO annual meeting ... May 5, 2004 Transgene announces First Quarter 2004 Financial Results ... Next Conferences May 12 to 14, 2004 Healthcare Conference ... Stock Quotes Date : 05.27.2004 (delayed) Last : Volume : Change : Nasdaq Last : $ 3.53(c) Volume : Change : Shareholder's Meeting on june 9, 2004 (Paris) Clinical Trials Job Opportunities French version Webm@ster

66. LSUSU Gene Therapy Program The gene therapy Program is located in the Department of Medicine and affiliated with the Stanley S. Scott Cancer Center and the Center for Human and Molecular Genetics at Louisiana State University Health Sciences Center at New Orleans. The major aim of the LSUHSC gene therapy Program is to develop new therapies for a series of genetic and acquired diseases including Cystic Fibrosis, Hemophilia, Krabbe's Disease and infectious diseases such as AIDS, TB, and pneumonia. http://www.medschool.lsumc.edu/GeneTherapy/Default.htm

67. BBC News | HEALTH | 'Bubble Boy' Saved By Gene Therapy In one of the first treatments of its kind, UK doctors have used gene therapy to cure a toddler of a potentially fatal disorder. gene therapy hurdles. http://news.bbc.co.uk/hi/english/health/newsid_1906000/1906999.stm

CATEGORIES TV RADIO COMMUNICATE ... INDEX SEARCH You are in: Health Front Page World UK ... AudioVideo SERVICES Daily E-mail News Ticker Mobiles/PDAs Feedback ... Low Graphics Wednesday, 3 April, 2002, 12:24 GMT 13:24 UK 'Bubble boy' saved by gene therapy Rhys can now play outside In one of the first treatments of its kind, UK doctors have used gene therapy to cure a toddler of a potentially fatal disorder. Scientists at Great Ormond Street Hospital in London successfully treated 18-month-old Rhys Evans, who had a condition preventing him from developing an immune system. The problem, called severe combined immunodeficiency (SCID) is caused by a single mutated gene, and meant that he had to live in sterile conditions or risk picking up a life-threatening infection. After his gene therapy, he was running around at home - he's a normal little boy now Dr Adrian Thrasher, Great Ormond Street Hospital Rhys, from Treharris, nr Cardiff, had spent much of his life in hospital prior to the treatment. Only one in between 50,000 and 100,000 births in the UK is affected by the disorder.

68. Richard Taylor : Functional Viral Formulation : 27/05/04 Interests in virology, molecular biology, biochemical engineering. Current work is on functional formulation of gene therapy vectors and vaccines. University of Cambridge, UK. http://www.cheng.cam.ac.uk/groups/biosci/rt.html

Richard Taylor Richard Taylor Viral Functional Formulation, Richard Taylor BioScience Engineering Group University of Cambridge Department of Chemical Engineering BioScience Group Front Page ... Contact Richard Taylor Researcher in Bioscience Engineering Richard Taylor graduated from Imperial College, London, with a BSc in Biochemistry in 2001 before moving to Cambridge. He is currently completing a PhD on the functional formulation of viral and DNA based gene therapeutics and is expecting to be in a position to leave Cambridge by October 2004. He holds a BBSRC Industrial CASE Studentship, and works with the cooperating company : Nektar Therapeutics , in Bradford. Details of current work can be found on Richard Taylor's Research page Further personal information can be obtained by following the links on the left of this page. In addition to research work, he teaches undergraduate students, in Medical and Natural Sciences Biochemistry and Molecular Cell Biology ) Working with students from Queens,

69. BBC NEWS | Health | Gene Therapy May Block HIV Spread gene therapy may block HIV spread. SEE ALSO gene therapy breakthrough 24 Feb 03 Health. Gene offers HIV drug success 06 Jan 02 Health. http://news.bbc.co.uk/2/hi/health/3707463.stm

News Sport Weather World Service ... Programmes Last Updated: Wednesday, 12 May, 2004, 23:29 GMT 00:29 UK E-mail this to a friend Printable version Gene therapy may block HIV spread There is no cure for HIV Three people with HIV have had a new experimental treatment to try to help them fight the disease. Scientists in the United States have used gene therapy techniques to try to boost their immune systems. Initial results from the trial have been promising, according to a report in New Scientist magazine. VIRxSYS, the company behind the technique, says it will test it on another two patients shortly, before embarking on a larger trial. Re-engineered cells The technique involves taking T cells from patients and re-engineering them so that they can destroy HIV. T cells are a type of white blood cell that can identify and destroy invading viruses. This is probably the most exciting of the anti-HIV strategies around at the moment Professor Alan Kingsman, Oxford BioMedica These cells are treated with a "gutted" form of HIV in the laboratory, which has been genetically engineered to stop HIV in the body from replicating and spreading. After the cells have been treated in this way, they are re-introduced into the body where they lie in wait until HIV attacks.

70. CNN.com - Health - New Plans Unveiled To Protect Gene Therapy Patients - March 7 CNN http://www.cnn.com/2000/HEALTH/03/07/gene.therapy/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: New plans unveiled to protect gene therapy patients March 7, 2000 Web posted at: 5:31 p.m. EST (2231 GMT) WASHINGTON (CNN) The Food and Drug Administration and the National Institutes of Health Tuesday announced two initiatives designed to better ensure the safety of patients who take part in gene therapy trials. The FDA is implementing a Gene Therapy Clinical Trial Monitoring Plan and the NIH is sponsoring a series of Gene Transfer Symposia. Both initiatives are designed to enhance current safety standards for patients enrolled in gene therapy trials.

71. Current Gene Therpy Editorial Page Online Articles PayPer-View. CURRENT. gene therapy. SCOPE OBJECTIVES. Barry J. Byrne. (gene therapy Center, Gainesville, FL, USA). Lung-Ji Chang. http://www.bentham.org/cgt/index2.htm

Forthcoming Articles Instructions for Authors Read the First issue on-line ... Online Articles: Pay-Per-View CURRENT GENE THERAPY Current Gene Therapy is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews on all aspects of gene therapy. The journal is aimed at all academic and industrial scientists who are interested in understanding either the pre-clinical or clinical research on gene therapy. The journal will serve as an expert forum to convey all the latest research on gene transfer and gene expression analysis, animal models, vector development and human clinical applications for the treatment of disease. EDITOR-IN-CHIEF Ignacio Anegon INSERM unit 437 30, boulevard Jean Monnet 44093 Nantes France FOUNDING EDITOR Pedro R. Lowenstein Gene Therapeutics Research Institute Los Angeles, CA, USA ASSOCIATE EDITORS Ian E. Alexander (Children's Hospital at Westmead, Westmead, NSW, Australia) Arthur L. Beaudet (Baylor College of Medicine, Houston, TX, USA) Vincenzo Bronte (Dept. of Oncology and Surgical Sci., Padova, Italy)

72. CNN - Father Of Gene Therapy Participant Says Researchers Acted 'irresponsibly' CNN http://www.cnn.com/2000/HEALTH/02/02/gene.therapy.02/index.html

[an error occurred while processing this directive] MAIN PAGE WORLD U.S. LOCAL ... daily almanac MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists. Enter your address: document.write(' '); Or: Get a free e-mail account E-MAIL DISCUSSION: message boards chat feedback CNN WEB SITES: AsiaNow Svenska Norge Danmark ... Italian FASTER ACCESS: europe japan TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: more networks transcripts SITE INFO: help contents search ad info ... jobs WEB SERVICES: health > story page Father of gene therapy participant says researchers acted 'irresponsibly' Jesse Gelsinger, 18, was receiving an experimental gene therapy for an incurable inherited liver disease prior to his death in September February 2, 2000 Web posted at: 3:42 p.m. EST (2042 GMT) From Medical Correspondent Elizabeth Cohen (CNN) The father of a young man who died during a gene therapy trial at the University of Pennsylvania told a Senate hearing on Wednesday that researchers acted "irresponsibly" and they downplayed possible risks to his son. Paul Gelsinger testified during the Senate Health, Education and Labor Subcommittee hearing on whether the Food and Drug Administration did the right thing in shutting down gene therapy trials at the University of Pennsylvania after 18-year-old Jesse Gelsinger of Tucson, Arizona, died in September.

73. CNN.com - Gene Therapy Hope For Cancer Patients - August 1, 2000 CNN http://www.cnn.com/2000/HEALTH/08/01/gene/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Gene therapy hope for cancer patients Scientists said the virus helped to destroy some cancer cells LONDON A gene therapy that has shrunk and even eradicated tumors in dying patients is being hailed by scientists as a significant breakthrough in the fight against cancer. The therapy works by using a genetically engineered virus to home in on and then destroy cancer cells.

74. New Scientist gene therapy fights HIV in human tests. 1357 13 May 04. Related Stories. Alzheimer s gene therapy trial shows early promise 28 April 2004. http://www.newscientist.com/news/news.jsp?id=ns99994982

75. University's Gene Therapy Lab Won't Perform Research On Humans CNN http://cnn.com/2000/HEALTH/05/25/genetherapy.ap/index.html

76. New Scientist Alzheimer s gene therapy trial shows early promise. The first gene therapy trial for Alzheimer s disease has delivered promising early results. http://www.newscientist.com/news/news.jsp?id=ns99994930

77. Collateral Therapeutics Develops nonsurgical gene therapy products for treating cardiovascular diseases, including coronary artery disease, peripheral vascular disease, congestive heart failure and heart attack. Product developments, video, and contacts. http://www.collateralthx.com/

Please see our Notes Regarding Gene Therapy Product Candidates Forward-Looking Statements , and Website Usage ; and our

78. CNN - Gene Therapy Researchers Defend Trial After Death Of Patient - December 10 CNN http://www.cnn.com/1999/HEALTH/12/10/gene.therapy.01/index.html

[an error occurred while processing this directive] MAIN PAGE WORLD U.S. LOCAL ... daily almanac MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists. Enter your address: document.write(' '); Or: Get a free e-mail account E-MAIL DISCUSSION: message boards chat feedback CNN WEB SITES: AsiaNow Svenska Norge Danmark ... Italian FASTER ACCESS: europe japan TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: more networks transcripts SITE INFO: help contents search ad info ... jobs WEB SERVICES: health > story page Gene therapy researchers defend trial after death of patient Jesse Gelsinger died after receiving experimental gene therapy for an inherited liver disease December 10, 1999 Web posted at: 3:09 a.m. EST (0809 GMT) In this story: Earlier patient signs not reported, FDA says Father says son would not have wanted trials halted Dispute over research animals RELATED STORIES, SITES From Medical Correspondent Pete Hartogs BETHESDA, Maryland (CNN) Researchers who led the gene therapy trial that left an 18-year-old man dead have defended their work to government investigators. Jesse Gelsinger of Tucson, Arizona, died in September after receiving an experimental gene therapy at the University of Pennsylvania for an inherited liver disease.

79. Gene Therapy: Molecular Bandage? What is gene therapy? The what and why of gene therapy research. Choosing Targets for gene therapy See how researchers decide which http://gslc.genetics.utah.edu/units/genetherapy/

Genetic Science Learning Center at the Eccles Institute of Human Genetics University of Utah Home ... What is Gene Therapy? The what and why of gene therapy research. Choosing Targets for Gene Therapy See how researchers decide which disorders are appropriate for gene therapy. Gene Delivery: The Key to Gene Therapy Putting therapeutic genes into cells is easier said than done. Find out why. Tools of the Trade Explore the methods for delivering genes into cells. From Research To Trials How long does it take? Follow a gene therapy treatment from the lab to the clinic. Challenges in Gene Therapy Why isn't gene therapy a smashing success? Space Doctor You are the doctor! Design and test gene therapy treatments with ailing aliens. New Approaches to Gene Therapy Examine some up-and-coming techniques in the gene therapy arena. Enhancement: Gene Therapy and Science Fiction Can we use gene therapy techniques to create designer humans? What are Some Issues in Gene Therapy? Consider some important questions in the debate over gene therapy research. Additional Resources Links to current news and in-depth information about gene therapy.

80. CNN.com - Health - Gene Therapy Research Targets Muscular Dystrophy - November 2 CNN http://cnn.com/2000/HEALTH/11/27/muscular.dystrohpy/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Gene therapy research targets muscular dystrophy By Michele Dula Baum CNN.com Health Writer (CNN) Imagine a virus that makes you well. Scientists at the University of Pittsburgh in Pennsylvania are zeroing in on the muscle-wasting disease of Duchenne Muscular Dystrophy using a genetically altered virus called an adeno-associated virus. Researchers hope the tiny package will eventually carry a healing punch.

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