81. ICI - SHE Report 2000 - Present - Endocrine Disruptors The hypothesis is that once consumed, these chemicals could disrupt the endocrine system, which controls and coordinates many of the basic human and animal http://www.ici.com/icishe/2000/pages/present04.htm

It has been suggested that exposure to very small amounts of certain chemical compounds, both natural and synthetic, could interfere with the way animals and people develop and reproduce. No conclusive evidence exists to support any link, but some researchers suspect that minute quantities of these chemicals - some used by industry - are finding their way into food and water. In fact many foods already contain much larger quantities of naturally occurring substances with similar properties, e.g. phytoestrogens in soya. The hypothesis is that once consumed, these chemicals could disrupt the endocrine system, which controls and co-ordinates many of the basic human and animal developmental and reproductive functions through hormones secreted by glands. Hormones themselves are chemical substances that travel through the bloodstream and cause responses in other parts of the body. Substances that interfere with the normal functioning of this complex system are known as 'endocrine disrupters'. Certain drugs such as the contraceptive pill are used intentionally to cause some of these effects. Attention is focused on chemicals that mimic or block the action of hormones; principally oestrogen, the female hormone, but also the male and thyroid hormones.

82. Endocrine Disruptors endocrine disruptors. Immunohistochemical demonstration of cytochrome P450 (CYP) isoforms in the submandibular gland (SMG) of carcinogentreated rats. http://www.cancerprev.org/Journal/Issues/24/101/205/

Cancer Detection and Prevention  Online Home Journal ... 2000 Meeting endocrine disruptors endocrine disruptors Immunohistochemical demonstration of cytochrome P450 (CYP) isoforms in the submandibular gland (SMG) of carcinogen-treated rats M Danz MD , A Lupp MD Cancer incidence study of pulp and paper mill workers PR Band MD , ND Le PhD Prostate tumor characteristics and prostate specific antigen (PSA)levels among farmers with prostate cancer J Gomes PhD , D Skarsgard MD Pesticides as endocrine disrupting chemicals: influence of exposure to anticholinesterases and pyrethroids on male sex hormones E Straube MD , W Straube MD Tyrosine phosphorylation and apoptosis in lymphocytes isolated from postmenopausal women treated with single dose of genistein W Lopaczynski MD PhD, L Tyndall MS, C Albright PhD, S Zeisel MD PhD The effects of dietary factors on estrogen responsive and non-responsive cells in vitro C Dees PhD , WR Thelin BS , L Bradlow PhD , DL Davis PhD , J Dan BS , S Foster MS , J Wimalasena PhD The effects of the dietary phytoestrogens daidzein and genistein on the incidence of spontaneous vulvar carcinomas in 129/J mice JE Thigpen PhD , J Locklear MD , J Mahler PhD , MF Goelz VMD , DB Forsythe MD

83. E H Home endocrine disruptors. Members of endocrine disruptors subgroup attending the Warsaw conference Please refer to links on left hand http://www.environmentandhealth.org/twgim/twge/twge_home.php

Background Dioxins and PCBs Heavy Metals Endocrine Disruptors ... TWG Members Endocrine Disruptors Members of Endocrine Disruptors sub-group attending the Warsaw conference Please refer to links on left hand side for information relating to this group

84. Larvae And Endocrine Disruptors Document Title Larvae and endocrine disruptors. Category Marine Science. Media Type Photos. Date of Image/Photo March 2002. Background http://picturethis.pnl.gov/picturet.nsf/All/5R7VPY?opendocument

85. Endocrine Disruptor Conference April 15, 2000 present. endocrine disruptors in the Great Lakes Region A OneDay Conference. Especially important are the effects of endocrine disruptors on human health. http://dept.kent.edu/wrri/endconf.htm

Kent State University Water Resources Research Institute School of Biomedical Sciences D epartment of Biological Sciences present Endocrine Disruptors in the Great Lakes Region: A One-Day Conference 15 April 2000 The purpose of this one day conference is to inform members of local and state agencies, health professionals, ecologists, physiologists and the general public on matters related to endocrine disruption in the Great Lakes region. The issues involve both ecological and physiological problems in invertebrates at the base of the food web, vertebrates such as fish and fowl, and mammals. Especially important are the effects of endocrine disruptors on human health. This conference intends to address all of these issues and to raise the question, “where do we go from here Topics include: General introductory overview of endocrine disruptors (EDs) in the Great Lakes region, their origin, fate and general ecological, physiological, and human health effects. Effects of EDs on invertebrates at the base of the food web.

86. GreenBiz | Essentials | Endocrine Disruptors endocrine disruptors Source GreenBiz.com. The Big Picture. A recent animals. Leads. EPA Endocrine Disruptor Screening program. The http://www.greenbiz.com/toolbox/essentials_third.cfm?LinkAdvID=4160

87. Toxicology & Environment WHO endocrine disruptors (through Google). WHO - Protection of the Human Environment. Pesticides, Toxins, endocrine disruptors - 2004. Phthalates. http://w3.uniroma1.it/MEDICFISIO/edc.htm

Department of Medical Physiopathology Biofluorimetry Lab University of Rome 'La Sapienza' ENDOCRINE DISRUPTING CHEMICALS with the last 6-months titles/abstracts published in leading J ournals updated April 13, 2004 other Site's Areas Agencies - Homepages - Institutions Organizations - Web resources A gencies (government) USA International A merican Plastics Council A TSDR - Agency for Toxic Substances and Disease Registry A TSDR's Hazardous Substance Release/Health Effects Database C ERHR - Center for the Evaluation of Risks to Human Reproduction C hemical Industry Homepage D anish Environmental Protection Agency E COTOX Database System E ndocrine Disruptors E ndocrine Disrupters Assessment Activities (OECD) E ndocrine disruptor related sites E ndocrine disruptors E ndocrine disruptors (actions in Europe) E ndocrine disruptors Beauty Secrets E ndocrine Disruptors Block Sperm Function - New Evidence That E ndocrine disruptors: Agents under study end End Points E ndocrine disruptors binding affinities database (needs authorization) E ndocrine Disruptor Research Initiative Project Inventory pages (EPA) E ndocrine disruptors: the endocrine theory E ndocrine Disruptors (Information and Computing Infrastructure for) E ndocrine Disruptors Research Initiative E ndocrine/Estrogen Letter E ndocrine modulators study group (European Chemical Industry Council) E NDS environmental links E nvironmental Agencies of the World E nvironmental Education Links E nvironmenmtal Research Foundation (Rachel's) browse issues E

88. Suspected Endocrine Disruptors. Organofluorine & Fluorine Pesticides. Fluoride A Suspected endocrine disruptors Organofluorine and Fluorine Pesticides, The Endocrine System Suspected Endocrine Disruptor Ref PAN Pesticides Database. http://www.fluoridealert.org/pesticides/effects.suspected.endocrine.htm

Pesticide Directory : A - E F G-P Q-Z ... Contact Project Search Pesticide Database: Suspected Endocrine Disruptors Organofluorine and Fluorine Pesticides The Endocrine System: Illustration by K. Born in Our Stolen Future by Theo Colborn, Dianne Dumanoski and JP Myers Note: This is not an exhaustive list. The review of data was performed in 2003. When time allows more information will be added. Bifenthrin Insecticide Acaricide - CAS Nos. 82657-04-3 (Cis); 83322-02-5 (Trans) "Suspected Endocrine Disruptor" Ref: PAN Pesticides Database Suspected Endocrine Disruptor Ref: June 14, 2001 - Implementation of the Community Strategy for Endocrine Disruptors - a range of substances suspected of interfering with the hormone systems of humans and wildlife. Communication from the Commission to the Council and the European Parliament. Commission of the European Communities, Brussels COM (2001) 262 final. http://www.fluoridealert.org/pesticides/Endocrine.Disruptors.EC2001.pdf

89. Developmental Biology Online: The Wingspread Consensus Statement The Wingspread Consensus Statement of 1991 began a move by scientists to influence government policy concerning potential endocrine disruptors. http://www.devbio.com/article.php?ch=22&id=217

90. Alexa Web Search - Subjects > Science > Environment > Environmental Health > End endocrine disruptors Subjects Science Environment Environmental Health endocrine disruptors. Browse, Best Selling Products in endocrine disruptors. http://www.alexa.com/browse/categories?catid=69715

91. Persistent Toxic Substances And Endocrine Disruptors PERSISTENT TOXIC SUBSTANCES AND endocrine disruptors. II. endocrine disruptors. Background A major issue in toxicology today is potential endocrine disruption. http://www.ijc.org/rel/boards/cglr/endocrine.html

PERSISTENT TOXIC SUBSTANCES AND ENDOCRINE DISRUPTORS Scoping Paper presented to the Council of Great Lakes Research Managers October 6, 1998 Ann Arbor, Michigan I. Persistent Toxic Substances (PTSs) A. Findings in Humans There is no evidence over the past five years of dramatic shifts in levels or types of bioaccumulating contaminants in tissues of residents of the Great Lakes basin. However, the levels of such contaminants in the tissues of people eating large amounts of Great Lakes fish continue to be several fold higher than in people who do not eat such fish. SOLEC 1996 Exposure At - risk populations continue to be exposed to PTSs. Some highly exposed groups have body burden levels 3-4 times higher than the background level (e.g., data from Schantz and coworkers on DDE, Hg, and PCBs). Fish consumption remains the major pathway for exposure to PTS in fish eaters. Levels of some contaminants in Great Lakes fish exceed state and federal guidelines. Contaminated sediments are also of concern. Sport fish eaters consume 2 to 3 times more fish than is estimated for the general population - FDA estimate is 6.5 grams/person-day (e.g., Schantz and coworkers report that high-fish eaters consume over 32 lbs/yr; Anderson and coworkers indicate that fish eaters on average consume 55 meals/yr with some consuming twice this amount; Kearney and coworkers found Lake Ontario fish eaters in Canada consumed approximately 21 g/day).

92. Wiley Canada::Environmental Endocrine Disruptors: A Handbook Of Property Data Wiley Canada Chemistry Industrial Chemistry Occupational Environmental Health Environmental endocrine disruptors A Handbook of Property Data. http://www.wiley.ca/WileyCDA/WileyTitle/productCd-0471191264.html

Shopping Cart My Account Help Contact Us By Keyword By Title By Author By ISBN By ISSN Wiley Canada Chemistry Industrial Chemistry Environmental Endocrine Disruptors: A Handbook of Property Data Related Subjects Impact in Environmental Engineering Paints, Pigments, Coatings Toxicology Biotechnology ... Food Science Technology Related Titles More By This Author Chemical Protective Clothing Performance (Hardcover) Chemical Protective Clothing Performance Index, 2nd Edition (Hardcover) Environmental Endocrine Disruptors: A Handbook of Property Data (Software) Principles of Environmental Sampling (Hardcover) ... Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles, 2nd Edition (Hardcover) by William C. Hinds Complying with TSCA Inventory Requirements: A Guide with Step-by-Step Processes for Chemical Manufacturers, Processors, and Importers (Hardcover) by Chan B. Thanawalla Values-Based Safety Process: Improving Your Safety Culture With Behavior-Based Safety, 2nd Edition (Hardcover) by Terry E. McSween Patty's Toxicology Mini Set Volume One and Eight (Hardcover) by Eula Bingham (Editor), Barbara Cohrssen (Editor)

93. THURSDAY GRC_title.gif (7962 bytes). Environmental endocrine disruptors. Plymouth State College, New Hampshire. THURSDAY. HOW ENVIRONMENTAL endocrine disruptors WORK. http://biology.uky.edu/Palmer/endocrinedisruptors.htm

Environmental Endocrine Disruptors Plymouth State College , New Hampshire June 18-23, 2000 CHAIR VICE CHAIR Brent D. Palmer University of Kentucky Ana Soto Tufts University Program SUNDAY Arrival and Registration 6:00 PM Dinner 7:30 PM Welcoming Remarks: Conference Chairs Brent D. Palmer, University of Kentucky Ana Soto, Tufts University 8:00 PM KEYNOTE ADDRESS Envirocrinology: A Rational System for the Study of Disease or Dysfunction in Humans and Ecosystems John McLachlan – Center for Bioenvironmental Research, Tulane University MONDAY THE REAL WORLD: LOW DOSE EFFECTS AND COMPLEX MIXTURES OF CHEMICALS AND ORGANISMS BREAKFAST Low Dose Effects and Complex Mixtures SESSION CHAIR: Dan Sheehan, National Center for Toxicological Research Developmental toxicity of hormonally active chemicals: diethylstilbestrol as an example Retha Newbold, National Institute of Environmental Health Sciences Effects of the soy isoflavone genistein in rodents at exposure levels comparable to those in humans. Berry Delclos, National Toxicology Program Overview of the immunotoxicological evaluation of five endocrine disrupters in the F1 generation of male and female Sprague Dawley rats.

94. Our Stolen Future: Arsenic Is An Endocrine Disruptor speculate that this low level endocrine disruption may be involved in links between Most hormone disruptors act by (1) affecting the amount of hormone (either http://www.ourstolenfuture.org/NewScience/oncompounds/2001kaltreideretal.htm

Navigate the site Newest developments Book Basics New Science Consensus Statements Commentary Myths vs. Reality Useful links Important Events Other Sources Other Languages About the Authors Kaltreider, RC, AM. Davis, JP Lariviere, and JW Hamilton 2001. Arsenic Alters the Function of the Glucocorticoid Receptor as a Transcription Factor Environmental Health Perspectives 109:245-251 press coverage of this research [29 Aug 2002: EPA assumption about risks of old arsenic treated decks and playground structures refuted Kaltreider et al . demonstrate that, at extremely low levels of exposure arsenic alters hormonal function in the glucocorticoid system. The metal interferes with glucocortoid signaling necessary to turning on genes involved in tumor suppression and other activities. By preventing these genes from turning on, arsenic may increase the risks of cancer. This new result may require radical strengthening of arsenic exposure standards, because it takes place at levels far beneath current safety thresholds. The glucocorticoid system is centrally involved in a wide range of physiological processes, ranging from the control of growth to glucose regulation and protein metabolism [

95. Endocrine Disrupters what are they? Wildlife woes Pesticides don t discriminate Human woes DES, DDT, PCB s, dioxin n more. How does the endocrine system work? Hormone basics http://whyfiles.org/045env_hormone/

In July, an EPA committee met in Chicago. Their problem: are synthetic chemicals causing hormonal chaos? [Posted August 7, 1997] Wildlife woes : Pesticides don't discriminate Human woes : DES, DDT, PCB's, dioxin 'n more Hormone basics Hormone confusion : How disrupters do their work History : DDT and eagles' eggs The EPA's action plan Prospects for success There are documents. Bibliography Credits Search

96. Endocrine Disrupters UPDATED 21 OCT 1998 . An EPA advisory group has suggested an approach for screening some 87,000 chemicals for their potential to disrupt the endocrine system. http://whyfiles.org/045env_hormone/main1.html

Fish and alligators are just two of the creatures under assault by endocrine disrupters in the environment. Crossed wires? EPA tackles hormones disrupters Talk about a tough assignment. Per Congressional edict, the Environmental Protection Agency (EPA) has begun mapping out a vast program to check whether synthetic chemicals can disrupt hormones in humans and animals. These "hormone disrupters" can cause cancer, birth defects and immune problems. Even incredibly tiny concentrations can interfere with reproduction. The hormone disrupters are more evidence that chemicals can be dangerous even if they don't cause cancer. In humans, as in animals, hormones have many communications jobs, affecting mood and memory, reproduction and development, virtually any biological process you can name. U P D A T E D 21 OCT 1998 . An EPA advisory group has suggested an approach for screening some 87,000 chemicals for their potential to disrupt the endocrine system. To slash the cost and complexity of the chore, the group eliminated 25,000 large molecules as unlikely to cross biological membranes. The Endocrine Disrupter Screening and Testing Advisory Committee also recommended testing certain combinations of chemicals, such as breast milk contaminants, plant-derived estrogen mimics, and gasoline. In addition to their human health effects, the chemicals will probably be screened for hormonal effects on wildlife. (See "EPA Unveils..." in the bibliography While the nervous system sends electrical signals along nerves, hormones drift to their destination through the blood to cells that have the correct receptor molecules on their outsides.

97. Endocrine Disrupters In July, an EPA committee met in Chicago. Their problem are synthetic chemicals causing hormonal chaos? Posted August 7, 1997 Wildlife woes Pesticides don't discriminate. Human woes DES, DDT, PCB's, dioxin 'n more. Hormone basics http://whyfiles.news.wisc.edu/045env_hormone

In July, an EPA committee met in Chicago. Their problem: are synthetic chemicals causing hormonal chaos? [Posted August 7, 1997] Wildlife woes : Pesticides don't discriminate Human woes : DES, DDT, PCB's, dioxin 'n more Hormone basics Hormone confusion : How disrupters do their work History : DDT and eagles' eggs The EPA's action plan Prospects for success There are documents. Bibliography Credits Search

98. OECD's Work On Endocrine Disrupters OECD s Activities in the Coordination of endocrine Disrupters Assessment. Please go to our new site. http://www.oecd.org/EHS/ENDOCRIN.HTM

OECD's Activities in the Co-ordination of Endocrine Disrupters Assessment Please go to our new site

99. Environment Canada's National Strategy For Addressing Endocrine Disrupting Subst endocrine Disrupting Substances (EDS). RECENTLY, SCIENTISTS HAVE SEEN A VARIETY OF endocrine RELATED EFFECTS IN FISH AND WILDLIFE http://www.ec.gc.ca/eds/fact/

Fact Sheet HTML Format PDF Format National Strategy Related Sites Endocrine Disrupting Substances (EDS) RECENTLY, SCIENTISTS HAVE SEEN A VARIETY OF ENDOCRINE- RELATED EFFECTS IN FISH AND WILDLIFE IN MANY PARTS OF THE WORLD, INCLUDING CANADA E ndocrine disrupting substances in the environment have become a concern over the past few years. Studies in Canada and other countries have shown that these substances can interact with the endocrine systems of many species and adversely affect growth, reproduction and development. Even at very low levels commonly found in the environment, many of these chemicals may have biological impacts. Scientists had previously thought low levels presented little risk to the environment. The consequences of endocrine disrupting substances to the health and sustainability of wildlife populations are subject to much scientific research and debate in Canada and around the world. What's New About Us Topics Publications ... Canada Site The Green Lane TM , Environment Canada's World Wide Web site Important Notices

100. Glossary the information site on endocrine disruption. This section is designed to introduce some key terms commonly used in endocrine modulator related discussions. http://www.emcom.ca/glossary/index.shtml

the information site on endocrine disruption This section is designed to introduce some key terms commonly used in endocrine modulator related discussions. Adrenal Glands : : The suprarenal or adrenal glands, each perched over one of the kidneys, are double glands. The core, or medulla, manufactures adrenalin, noradrenalin and a small amount of dopamine. These chemical messengers are also produced by the nerve endings of the sympathetic nervous system. The outer layer of the gland is called the cortex. The adrenal cortex produces three groups of corticosteroids; mineralocorticoids (aldosterone) - control electrolyte and water balance, glucocorticoids (cortisol)- influence carbohydrate metabolism and sex steroid hormones (androgens, DHEA). Androgen / Anti-Androgen : Androgens are the natural sex hormones of male animals, responsible for development of an animal in the male form and for the development of secondary sexual characteristics at puberty (e.g. hair and muscle growth, deepening of the voice.) The major androgen is testosterone. Anti-androgens are substances which block the function of normal androgens. They bind just like normal androgens to androgen receptors, but unlike androgens, this binding does not result in activation of the receptors. Thus anti-androgens block the receptors from stimulation by androgens.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 5     81-100 of 102    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20