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         Schally Andrew V:     more detail
  1. Biography - Schally, Andrew V(ictor) (1926-): An article from: Contemporary Authors by Gale Reference Team, 2002-01-01
  2. The Nobel Duel by Nicholas Wade, 1981-09

1. Science In Poland - Andrew V. Schally
Andrew V. Schally. 1926 Andrew V. Schally was born on November 30, 1926 in Wilno, Poland (now Lithuania). Schally fled Poland with his family in 1939.
http://hum.amu.edu.pl/~zbzw/ph/sci/avs.htm
Andrew V. Schally
GnRH ( Gonadotropin Releasing Hormone ), is a small hormone composed of ten amino acids and controls release of hormones from the anterior pituitary gland ( Follicle Stimulatind Hormone (FSH) and Luteinizing Hormone (LH)) that affect ovarian function. In Gonadotropin Releasing Hormone Source: Treatment of Endometriosis by Richard W. Tureck Andrew Schally at Tulane University in New Orelans (Louisiana) continues to maintain considerable National Institutes of Health funding for his work in neuroendocrine, neurobiological and related neuroscience research. New Orleans is recognized internationally for contributions to this field including Schally's Nobel Prize discovery and synthesis of the hormones from the brain that control the release and production of other hormones from the master pituitary gland. Andrew V. Schally became the prominent member of the Polish Institute of Arts and Sciences of America. Schally received The Heath Memorial Award (1989). He is a honorary member of the Worldwide Hungarian Medical Academy at the Second International Congress of WHMA which was held in Budapest, Hungary, August 25-27, 1994. Related links Andrew V. Schally - The Nobel Prize in Physiology or Medicine 1977

2. Andrew V. Schally
Andrew V. Schally 1926 Nagroda Nobla 1977 w dziedzinie medycyny. Historianarodów jest takze historia wojen, a losy poszczególnych
http://www.polonialife.ca/polacy_aschally.htm
Andrew V. Schally
Nagroda Nobla 1977 w dziedzinie medycyny
Historia narodów jest tak¿e histori± wojen, a losy poszczególnych obywateli niczym innym jak sk³adank± narodowych d±¿enñ, marzeñ i potrzeb. Ziemia polska przedeptana kampaniami wojennymi obfituje w groby znane i nieznane i w takie karty historii, które zapisywane by³y przez Polaków z urodzenia i Polaków z wyboru, mi³ujacych kraj i oddaj±cych mu najwiekszy dar - pracê ca³ego ¿ycia. Po tym wstêpie latwo mi bêdzie przej¶æ do prezentacji cz³owieka, który dwadzie¶cia dwa lata temu otrzyma³ nagrodê Nobla w dziedzinie nauk medycznych i oficjalnie przyznaje siê do koneksji z Polsk±.
Zreszt± pisz±c swój zyciorys podkre¶la³, ¿e urodzi³ siê w Wilnie, w Polsce, 30 listopada 1926 roku i jest pochodzenia polsko - austro - wegiersko - francusko - szwedzkiego. Kto to taki? Wybitny endokrynolog, badacz i lekarz jednocze¶nie, marzyciel zapatrzony w przysz³o¶æ dziedziny, któr± obra³ sobie jako przedmiot dociekañ naukowych
Andrew Victor Schally Po wojnie pozosta³ w Szkocji i tam tak¿e Andrzej Schally ukoñczy³ szko³ê ¶rednia, sk±d wyjecha³ do Londynu na studia chemiczne. Pracê naukow± rozpocz±³ w National Institute of Medical Research. Chyba nie odwa¿y³abym siê o Andrzeju pisaæ, bo na pocz±tek zaplanowa³am prezentacjê Polaków pracuj±cych dla wspólnego ¶wiatowego dziedzictwa, a w jakis sposób zwi±zanych tak¿e z Kanad±, gdyby nie fakt, ¿e w³a¶nie w Kanadzie, w Montrealu podj±³ pracê w 1952 roku w charakterze pracownika naukowego na Uniwersytecie McGill i w³a¶nie w Kanadzie (jak s±dzê) wykszta³ci³y siê jego zainteresowania endokrynologi±. Endokrynologia jest poddyscyplin± medyczn± do¶æ m³od±, ale ma ju¿ wielu entuzjastów wierz±cych g³êboko, ¿e zglêbianie tej¿e pomo¿e ujawniæ procesy dot±d mo¿e omijane, mo¿e lekcewa¿one, ale z pewno¶ci± traktowane po macoszemu.

3. DICCIONARIO DE TERMINOLOGIA MEDICA
Translate this page 1977, GUILLEMIN, Roger (N. 1924) Estados Unidos, schally andrew v.(n. 1926) Estados Unidos, YALOW, Rosalyn (n 1921) Estados Unidos.
http://www.iqb.es/diccio/n/nobel08.htm
Premios Nobel
SUTHERLAND, Earl W (1915-1974) Estados Unidos por sus estudios sobre las hormonas EDELMAN, Gerald, M (n 1921) Estados Unidos; PORTER, Rodney por sus estudios sobre los anticuerpos Von FRISCH, Karl (1886 - 1982) Alemania; LORENZ, Conrad (1903 - 1989) Austria; TINBERGEN, Nikolas (1907 - 1988) Holanda por sus estudios sobre la conducta humana CLAUDE Albert DUVE, Christian PALADE, George E . (n. 1912) Estados Unidos BALTIMORE, David (N. 1938) Estados Unidos, DULBECCO, Renato (n 1914) Estados Unidos; TEMIN, Howard Martin (1934-1994) Estados Unidos BLUMBERG Baruch S. (n.1925) Estados Unidos, GAJDUSEK, D. Carleton (n 1923) Estados Unidos GUILLEMIN, Roger ( N. 1924) Estados Unidos, SCHALLY Andrew V. (n. 1926) Estados Unidos, YALOW, Rosalyn (n 1921) Estados Unidos ARBER Werner (n. 1929) Suiza, NATHANS, Daniel (1928-1999) Estados Unidos; SMITH Hamilton O . (n 1931) Estados Unidos por sus descubrimientos sobre los enzimas de restriccion CORMACK, Allan M.

4. Andrew Victor Schally
Andrew Victor Schally. Andrew Victor Schally (1926) Polishborn USendocrinologist whose work in isolating and synthesizing hormones
http://www.nobel-winners.com/Medicine/andrew_victor_schally.html
Andrew Victor Schally
Andrew Victor Schally
Polish-born U.S. endocrinologist whose work in isolating and synthesizing hormones that are produced by the hypothalamus and control the activities of other hormone-producing glands led to his being awarded a share (with Roger Guillemin and Rosalyn Yalow) of the 1977 Nobel Prize for Physiology or Medicine.
Schally fled Poland with his family in 1939. He attended the University of London and worked for three years at the National Institute for Medical Research in London before travelling to Montreal to enter McGill University. He graduated in 1955 and two years later took a Ph.D. in biochemistry. From 1957 to 1962 he was associated with Baylor University in Houston, Texas, and in the latter year he became chief of endocrine and polypeptide laboratories at the Veterans Administration (VA) Medical Center in New Orleans. At the same time he joined the medical faculty of the Tulane University School of Medicine, becoming professor in 1967. He became senior medical investigator with the VA in 1973. Schally became a U.S. citizen in 1962. Among Schally's chief accomplishments were the synthesis of TRH (thyrotropin-releasing hormone), the isolation and synthesis of LH-RH (luteinizing hormone-releasing hormone), and studies of the action of somatostatin.

5. ALFRED NOBEL (Fig
Translate this page 37) Blumberg Baruch S. 1977 38) Guillemin Roger CL. 39) schally andrew v. 40) YalowRosalin S. 1979 41) Cormack Allan Macleod. 42) Hounsfield Godfrey Newbold.
http://w3.uniroma1.it/anat3b/pages/storia.htm
ALFRED NOBEL (Fig.1) nacque a Stoccolma il 21 Ottobre 1883 e morì a Sanremo il 10 Dicembre 1896. Fu cittadino del mondo nel senso che passò la sua vita in quasi tutti i paesi dell'Europa. Nato in Svezia passò la sua adolescenza a San Pietroburgo in Russia, operò in molti paesi europei vivendo per lo più a Parigi. Trascorse gli ultimi anni della sua vita in Italia a San Remo dove abitò in una splendida dimora tuttora facente parte della fondazione Nobel. Parlava e scriveva correttamente in sei lingue, fu chimico ed ingegnere celebre per le sue redditizie attività industriali e per le sue invenzioni (compresa quella della dinamite). Ebbe interesse per la letteratura e la poesia e finanziò a più riprese movimenti pacifisti. Nel 1895, un anno prima della sua morte, elaborò il suo famoso testamento. Ma poichè diffidava degli avvocati, volle stendere da solo le sue ultime volontà, commettendo una serie di errori che furono superati solo grazie alla abilità del suo esecutore testamentario Ragnar Sohlman.

6. Andrew V. Schally - Autobiography
andrew V. schally – Autobiography. I was born in Wilno, Poland on November30, 1926, being of Polish, AustroHungarian, French and Swedish ancestry.
http://www.nobel.se/medicine/laureates/1977/schally-autobio.html
My interest in medical research started at the age of 23, when I joined the National Institute of Medical Research (NIMR, MRC) Mill Hill, London, England. I was fortunate to work with and be exposed to the stimulating influences of such scientists as Dr. D. F. Elliott, Sir Charles Harington, Dr. R.R. Porter , Dr. A.J.P. Martin , Dr. R. Pitt-Rivers, Dr. J. Gross, Dr. T. S. Work, Dr. H. Fraenkel-Conrat, and Dr. W. Cornforth , several of whom later won Nobel Prizes for chemistry or physiology and medicine. Although my position was very junior at Mill Hill, my work was appreciated and this was a source of tremendous satisfaction for me, inasmuch as this recognition came from scientists of such caliber. I learned much in those 2 1/2 years, not only technical expertise but also the philosophy of research and a systematic approach to scientific investigations. These years of instruction (1950-1952) were decisive in providing inspiration, training, and laboratory discipline and profoundly influenced the course of my career. In fact, it was at NIMR, Mill Hill where I endured my "baptism of fire" in medical research and became addicted to it. In May, 1952, I moved to Montreal, Canada where I was given the opportunity to work and study at McGill University . There I learned endocrinology from the brilliant lectures by Professor D. L. Thomson and from my work with Dr. M. Saffran in the laboratory of experimental therapeutics of the Allan Memorial Institute of Psychiatry headed by Dr. R. A. Cleghorn. The work at this laboratory was devoted to ACTH and adrenal cortical steroids. That period marked the beginning of my interest in the relationship between brain function and endocrine activity, and it was there in 1954 that my involvement in the hypothalamic field began.

7. Roger C. L. Guillemin 1924 - Andrew V. Schally 1926
In their separate laboratories, Guillemin and schally investigated how the brain controls the hormoneproducing of hypothalamic hormones." andrew V. schally, Les Prix Nobel, 1977.
http://history.nih.gov/exhibits/rodbell/1_Gillemin_Schally.htm
I n their separate laboratories, Guillemin and Schally investigated how the brain controls the hormone -producing glands. During the 1950s, they were able to extract substances which direct the release of hormones from the pituitary , thyroid, and gonad glands from the part of the brain called the hypothalmus. Not until 1969, however, was either laboratory able to isolate and purify one of those substances, Thyroid Releasing Factor (TRF). TRF released Thyroid Stimulating Hormone (TSH). This discovery opened up new avenues of research into how the brain and hormones work. For more information about Guillemin and Schally's work, see www.nobel.se/medicine/laureates/1977/press.html
"I always hoped that somehow I could one day work in a laboratory." Roger C. L. Guillemin, Les Prix Nobel, 1977.
Roger C. L. Guillemin was born in France on January 11, 1924 and studied at the School of Medicine in Dijon, graduating in 1949. He moved to Canada and studied at the University of Montreal. Later he taught at Baylor University College of Medicine in Houston, Texas and became interested in how the pituitary gland was controlled. He established the Laboratories for Neuroendocrinology at the Salk Institute in San Diego. Guillemin also served on several National Institutes of Health advisory groups over the years. For more information about Guillemin, see

8. A V SCHALLY And A NAGY: Chemotherapy Targeted To Hormone Receptors On Tumors (Eu
on targeting of cytotoxic peptide conjugates to their receptors on tumors. andrew V schally and Attila Nagy should be addressed to A V schally, Veterans Affairs Medical Center, 1601
http://www.eje.org/eje/141/eje1410001.htm
REVIEW: Cancer chemotherapy based on targeting of cytotoxic peptide conjugates to their receptors on tumors
Andrew V Schally and Attila Nagy
Section of Experimental Medicine, Tulane University School of Medicine and Endocrine, Polypeptide, and Cancer Institute, The Veterans Affairs Medical Center, New Orleans, Los Angeles USA (Correspondence should be addressed to A V Schally, Veterans Affairs Medical Center, 1601 Perdido Street, New Orleans, Los Angeles, USA)
Abstract
In view of non-specific toxicity of most chemotherapeutic agents against normal cells, the development of targeted chemotherapy is warranted. Efficient targeting of chemotherapeutic drugs to the cancerous area could be of great benefit for patients with advanced or metastatic tumors. Targeted cytotoxic peptide conjugates are hybrid molecules composed of a peptide carrier which binds to receptors on tumors and a cytotoxic moiety. New cytotoxic analogs of LH-RH, AN-152 in which doxorubicin (DOX) is linked to [D-Lys ]LH-RH, and AN-207 which consists of 2- pyrrolino-DOX (AN-201) coupled to the same carrier, show high-affinity binding and are much less toxic and more effective in vivo Download the FULL TEXT of this article in Acrobat PDF format.

9. Andrew V. Schally Winner Of The 1977 Nobel Prize In Medicine
andrew V. schally, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. andrew V. schally. 1977 Nobel Laureate in Medicine Links added by Nobel Internet Archive visitors. andrew V. schally( submitted by Zbigniew Zwolinski
http://www.almaz.com/nobel/medicine/1977b.html
A NDREW V S CHALLY
1977 Nobel Laureate in Medicine
    for their discoveries concerning the peptide hormone production of the brain
Background
    Born: 1926
    Place of Birth: Wilno, Poland
    Residence: U.S.A.
    Affiliation Veterans Administration Hospital, New Orleans, LA
Featured Internet Links Links added by Nobel Internet Archive visitors Back to The Nobel Prize Internet Archive
Literature
... Medicine We always welcome your feedback and comments

10. Medicine 1977
peptide hormones . Roger Guillemin, andrew V. schally, Rosalyn Yalow.1/4 of the prize, 1/4 of the prize, 1/2 of the prize. USA, USA, USA.The
http://www.nobel.se/medicine/laureates/1977/
The Nobel Prize in Physiology or Medicine 1977
"for their discoveries concerning the peptide hormone production of the brain" "for the development of radioimmunoassays of peptide hormones" Roger Guillemin Andrew V. Schally Rosalyn Yalow 1/4 of the prize 1/4 of the prize 1/2 of the prize USA USA USA The Salk Institute
San Diego, CA, USA Veterans Administration Hospital
New Orleans, LA, USA Veterans Administration Hospital
Bronx, NY, USA b. 1924
(in Dijon, France) b. 1926
(in Wilno, Poland) b. 1921 The Nobel Prize in Physiology or Medicine 1977
Press Release

Presentation Speech
Roger Guillemin ...
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The 1977 Prize in:
Physics

Chemistry
Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified June 30, 2003 The Official Web Site of The Nobel Foundation

11. Andrew V. Schally Winner Of The 1977 Nobel Prize In Medicine
andrew V. schally, a Nobel Prize Laureate in Physiology and Medicine, at the NobelPrize Internet Archive. andrew V. schally. 1977 Nobel Laureate in Medicine
http://almaz.com/nobel/medicine/1977b.html
A NDREW V S CHALLY
1977 Nobel Laureate in Medicine
    for their discoveries concerning the peptide hormone production of the brain
Background
    Born: 1926
    Place of Birth: Wilno, Poland
    Residence: U.S.A.
    Affiliation Veterans Administration Hospital, New Orleans, LA
Featured Internet Links Links added by Nobel Internet Archive visitors Back to The Nobel Prize Internet Archive
Literature
... Medicine We always welcome your feedback and comments

12. Index Of Nobel Laureates In Medicine
Rous, Peyton, 1966. Sakmann, Bert, 1991. Samuelsson, Bengt I. 1982. schally,andrew V. 1977. Sharp, Phillip A. 1993. Sherrington, Sir Charles Scott, 1932.
http://almaz.com/nobel/medicine/alpha.html
ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE
Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

13. Schally, Andrew Victor
schally, andrew Victor. ( b. Nov. 30, 1926, Wilno, Pol Medicine. schally fled Poland with his family in 1939 VA in 1973. schally became a U.S. citizen in 1962
http://www.britannica.com/nobel/micro/530_42.html
Schally, Andrew Victor
(b. Nov. 30, 1926, Wilno, Pol.), Polish-born U.S. endocrinologist whose work in isolating and synthesizing hormones that are produced by the hypothalamus and control the activities of other hormone-producing glands led to his being awarded a share (with Roger Guillemin and Rosalyn Yalow ) of the 1977 Nobel Prize for Physiology or Medicine Schally fled Poland with his family in 1939. He attended the University of London and worked for three years at the National Institute for Medical Research in London before travelling to Montreal to enter McGill University. He graduated in 1955 and two years later took a Ph.D. in biochemistry. From 1957 to 1962 he was associated with Baylor University in Houston, Texas, and in the latter year he became chief of endocrine and polypeptide laboratories at the Veterans Administration (VA) Medical Center in New Orleans. At the same time he joined the medical faculty of the Tulane University School of Medicine, becoming professor in 1967. He became senior medical investigator with the VA in 1973. Schally became a U.S. citizen in 1962. Among Schally's chief accomplishments were the synthesis of TRH (thyrotropin-releasing hormone), the isolation and synthesis of LH-RH (luteinizing hormone-releasing hormone), and studies of the action of somatostatin.

14. Andrew V. Schally --  Encyclopædia Britannica
schally, andrew V. Encyclopædia Britannica Article. andrew V. schally. To citethis page MLA style andrew V. schally. Encyclopædia Britannica. 2004.
http://www.britannica.com/eb/article?eu=67787&tocid=0&query=new hampshire v. lou

15. Andrew V. Schally --  Encyclopædia Britannica
Encyclopædia Britannica, schally, andrew V. Encyclopædia Britannica Article. Tocite this page MLA style andrew V. schally. Encyclopædia Britannica. 2004.
http://www.britannica.com/eb/article?eu=67787&source=SEO

16. Hum. Reprod. -- Schally 15 (9): 2059
andrew V. schally. Professor of Medicine, Head, Section of Experimental Medicine, Tulane University School of Medicine Matsuo et al., 1971a, b; schally et al., 1971a, b
http://humrep.oupjournals.org/cgi/content/full/15/9/2059
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Human Reproduction, Vol. 15, No. 9, 2059-2061, September 2000
European Society of Human Reproduction and Embryology
Letters to the Editor
Use of GnRH in preference to LH-RH terminology in scientific papers
Andrew V. Schally Professor of Medicine, Head, Section of Experimental Medicine, Tulane University School of Medicine, Chief, Endocrine, Polypeptide, and Cancer Institute, The Veterans Affairs Medical Center, New Orleans, Louisiana, USA Distinguished Medical Research Scientist, Department of Veteran Affairs Nobel Prize in Medicine, 1977 Dear Sir, I was disappointed by your recommendation to use GnRH in preferene to LH-RH.

17. Schally, Andrew V.
schally, andrew V. (1926). I was born in Wilno, Poland on November 30,1926, being of Polish, Austro-Hungarian, French and Swedish ancestry.
http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/S/Schally/Schall
Schally, Andrew V. Beethoven Brahms and Liszt
In 1961 I spent about one month at the Institute of Biochemistry in Uppsala with Dr. J. Porath where I gained useful experience in the use of Sephadex and column electrophoresis. I also visited Dr. V. Mutt and the late Professor E. Jorpes in Stockholm, in connection with our collaboration on gastrointestinal hormones, and I was encouraged that they and other astute scientists had confidence in our work and the foresight to appreciate the possible scientific and medical importance of hypothalamic hormones.
It was my good fortune that in 1964 Dr. A. J. Kastin and in 1965 Dr. A. Arimura came to join our laboratory. Dr. Abba Kastin was mainly interested in continuing his work on control of release of MSH and in helping us in clinical work on hypothalamic hormones. He quickly became my best friend and a most efficient collaborator. Dr. Akira Arimura was an experienced physiologist and endocrinologist. Because of his great knowledge, enthusiasm and very hard work, he made great contributions in all phases of our program, and also broadened it with many independent ideas, especially in immunology. Other excellent collaborators at that time included Drs. I. Ishida, A. Kuroshima, T. Saito, and S. Sawano from Japan, and Dr. E. E. Muller from Italy.
The identification of TRH removed the skepticism surrounding the work on the hypothalamus and I realized that many workers would now be attracted to the field. We therefore redoubled our efforts on LH-RH.

18. PNAS -- Abstracts: Kiaris And Schally 96 (1): 226
Hippokratis Kiaris and andrew V. schally* Endocrine, Polypeptide, and Cancer Institute, Veterans Affairs Medical Center Contributed by andrew V. schally, November 16, 1998
http://www.pnas.org/cgi/content/abstract/96/1/226

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Vol. 96, Issue 1, 226-231, January 5, 1999
Medical Sciences
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone
telomerase repeat amplification assay telomerase catalytic subunit regulation tumor regression down-regulation of telomerase gene Hippokratis Kiaris and Andrew V. Schally Endocrine, Polypeptide, and Cancer Institute, Veterans Affairs Medical Center, New Orleans, LA 70112-1262; and Section of Experimental Medicine, Tulane University School of Medicine, New Orleans, LA 70112-2699 Contributed by Andrew V. Schally, November 16, 1998 Antagonists of growth hormone-releasing hormone (GH-RH) inhibit the growth of various tumors through mechanisms that involve the suppression of the insulin-like growth factor I and/or insulin-like growth factor II levels or secretion. In the present study, we

19. Themes Geography History History Prize Winners Nobel
Martin. 1976, Blumberg, Baruch S. Gajdusek, D. Carleton. 1977, Guillemin,Roger - schally, andrew V. - Yalow, Rosalyn Sussman. 1978,
http://www.cartage.org.lb/en/themes/GeogHist/histories/prizewinners/nobelprize/m
Themes History Prize Winners Nobel Prize
Year
Winners
Behring, Emil Adolf von Ross, Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich ... Bárány, Robert The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section Bordet, Jules Krogh, Schack August Steenberg The prize money was allocated to the Special Fund of this prize section Hill, Archibald Vivian Meyerhof, Otto Fritz Banting, Frederick Grant Macleod, John James Richard ... Einthoven, Willem The prize money was allocated to the Special Fund of this prize section Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan ... Domagk, Gerhard The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section Dam, Henrik Carl Peter

20. PNAS -- Abstracts: Kovacs And Schally 98 (21): 12197
Magdolna Kovacs* , and andrew V. schally* § Contributed by andrew V. schally, August 21, 2001
http://www.pnas.org/cgi/content/abstract/98/21/12197
October 9, 2001
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Medical Sciences
Comparison of mechanisms of action of luteinizing hormone-releasing hormone (LHRH) antagonist cetrorelix and LHRH agonist triptorelin on the gene expression of pituitary LHRH receptors in rats
Magdolna Kovacs and Andrew V. Schally Endocrine, Polypeptide, and Cancer Institute, Veterans Affairs Medical Center, New Orleans, LA 70112; and Section of Experimental Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112 Contributed by Andrew V. Schally, August 21, 2001 The mechanisms through which luteinizing hormone (LH)-releasing hormone (LHRH) antagonists suppress pituitary gonadotroph functions and LHRH-receptor (LHRH-R) expression are incompletely understood. Consequently, we investigated the direct effect of

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