1. Bert Sakmann Bert Sakmann. Along with Erwin Neher, Bert Sakmann developed the patchclamp technique to record the small ionic currents (only a http://web.sfn.org/wrensite/projects/patch_clamp/sakmann.htm

Bert Sakmann Along with Erwin Neher , Bert Sakmann developed the patch clamp technique to record the small ionic currents (only a few picoamperes) that flow through a single ion channel in neuronal membranes. In 1976 Sakmann and Neher made the first recordings of single ion channel currents in nicotinic acetylcholine receptors from muscle. They were awarded the Nobel Prize for this work in 1991. Current work in Professor Sakmann's group is focused on understanding fast signaling in neurons, including biophysical and molecular mechanisms underlying synaptic transmission. Biographical Sketch: Discovery H O M E B A S I C S O B J E C T I V E S ... A P P L I C A T I O N S

2. Bert Sakmann Bert Sakmann. Bert Sakmann (1942) German medical doctor and researchscientist who in 1991, together with German physicist Erwin http://www.nobel-winners.com/Medicine/bert_sakmann.html

Bert Sakmann Bert Sakmann German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher, won the Nobel Prize for Physiology or Medicine for research into basic cell function and for their development of the patch-clamp techniquea laboratory method widely used in cell biology and neuroscience to detect electrical currents as small as a trillionth of an ampere through cell membranes. From 1969 to 1970 Sakmann served as a research assistant in the department of neurophysiology at the Max Planck Institute for Psychiatry and then finished his postdoctoral studies in the department of biophysics at University College, London. After receiving his medical degree from the University of Gottingen in 1974, Sakmann joined the department of neurobiology at the Max Planck Institute for Biophysical Chemistry, where he shared laboratory space with Neher. Working together, the two men used the patch-clamp technique to conclusively establish the existence of characteristic sets of ion channels in cell membranessome of which permit the flow of only positive ions, while others pass only negatively charged ions. This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders. These discoveries enabled the development of new and more specific drug therapies.

3. Bert Sakmann Textbooks Textbooks & Books Price Comparison - Direct Textbook Direct Textbook, Compare Prices on New Used College Textbooks. Searchby ISBN, Title, Author, Keyword, or Advanced. Bert Sakmann Textbooks. http://www.directtextbook.com/author/bert-sakmann

Search by ISBN, Title, Author, Keyword, or Advanced Bert Sakmann Textbooks Single-Channel Recording Hardcover - Show all editions Bert Sakmann Erwin Neher , August, 1995 Plenum Pr List Price: $138.00 Customer Reviews: ISBN: 030644870X Fidia Research Foundation Neuroscience Award Lectures 1990-1991 Hardcover - Show all editions Michael J. Berridge Bert Sakmann John A. Connor ... Federigo Sicuteri , January, 1992 Raven Press List Price: $28.50 ISBN: 0881678589 Love Us? Bookmark Us or Link to Us Don't Love Us? Help Us Improve Home Browse Bookstores ... LD Web Design Company Textbooks Subjects Architecture Textbooks Business Textbooks Business Textbooks Computer Textbooks ... Sell Textbooks Online Get the best prices when selling your used textbooks online by comparing buyback companies. Your Book's ISBN Subscribe to Our Newsletter Be the first to hear about coupons, sales, and other money saving ideas. Your Email Address

4. Especiales Diario Médico Translate this page Bert Sakmann y Erwin Neher. Bert Sakmann. Bert sakmann bert Sakmann nació en 1942en en Stuttgart (Alemania). Estudió Medicina en la Universidad de Gottingen. http://www.diariomedico.com/medicinasiglo/nobel1991.html

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5. LT Awardees CARLETON Alan (FRANCE) sakmann bert (Host Supervisor) Department of Cell Physiology Max-Planck-Institute for Medical Research - HEIDELBERG - GERMANY In vivo http://www.hfsp.org/awardees/AwardsLT2003.php

Human Frontier Science Program Home About HFSP How to Apply Awardees ... Links Long-Term Fellows Award Year 2003 The awards are listed alphabetically by principal applicant. You can use your browser's "find" function to locate specific keywords on this page. Return to Long-Term Fellows top page AMADOR Virginia (SPAIN) PAGANO Michele (Host Supervisor) Pathology Department - New York University - NEW YORK - USA Study of the function of human Fbl4, an F-box protein localized on the centrosomes abstract BACHAND François (CANADA) SILVER Pamela A. (Host Supervisor) Dept. of Cancer Biology and Biological Chemistry and Molecular Pharmacology - Dana Farber Cancer Institute - BOSTON - USA The role of protein methylation in the regulation of gene expression and growth control abstract BARDIN Allison (USA) SCHWEISGUTH François (Host Supervisor) Département de Biologie - Ecole Normale Supérieure - PARIS - FRANCE Investigating neuralized regulation during asymmetric cell division in Drosophila melanogaster abstract BECAMEL Carine (FRANCE) MALINOW Roberto (Host Supervisor) Department of Neuroscience - Cold Spring Harbor Laboratory - COLD SPRING HARBOR - USA Molecular mechanisms controlling AMPA receptor synaptic delivery abstract BECSKEI Attila (HUNGARY) VAN OUDENAARDEN Alexander (Host Supervisor) Department of Physics - Massachusetts Institute of Technology - CAMBRIDGE - USA Spatial dynamics of kinase and phosphatase reactions abstract BERDNIK Daniela (AUSTRIA)

6. Long-Term Fellows 1999 Brain HOFFMAN Dax (USA) (Fellow) sakmann bert (Host) Department of Cell Physiology, MaxPlanck-Institutefor Medical Research, Heidelberg, GERMANY Construction and http://www.hfsp.org/awardees/AwardsLTB1999.htm

@import "/style/hfsp.css"; June 5, 2004 Home About HFSP How to Apply Awardees ... For Awardees Only AWARD YEAR 1999 - Neuroscience Long-Term Fellows The awards are listed alphabetically by principal applicant. You can use your browser's "find" function to locate specific keywords on this page. Return to Long-Term Fellows top page AKASSOGLOU Katerina (GREECE) (Fellow) STRICKLAND Sidney (Host) Department of Pharmacology, State University of New York, Stony Brook, USA The role of laminin in neuronal survival and degeneration Abstract ANDERSEN POO Mu-Ming (Host) Department of Biology, University of California, La Jolla, USA Long-range signaling in neurons AUGER ATTWELL David (Host) Department of Physiology, University College London, London, UK Glial Ca2+ waves, transmitter release and control of blood flow in the retina AVIDOR-REISS Tomer (ISRAEL) (Fellow) ZUCKER Charles (Host) Dept. of Biology and Neuroscience, University of California, La Jolla, USA The molecular basis of ciliated mechanosensory transduction in Drosophila melanogaster BAMJI Shernaz (CANADA) (Fellow) REICHARDT Louis F. (Host)

7. Bert Sakmann Toys Games. Click Here. Encyclopedia. Main Page See live article,Bert Sakmann. Bert Sakmann is a German cell physiologist. He http://www.sciencedaily.com/encyclopedia/bert_sakmann

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8. Maandoverzicht Aanwinsten MBU Aanwinstdatum 12MAR-04. Auteur sakmann bert. Titel Single-channel recordinged. by Bert Sakmann and Erwin Neher. Plaats New York, NY. Jaar 1995. http://alephuitvoer.library.uu.nl:8000/pub/aanwinst/archief/maa/MBU-MBUBK.htm

Maandoverzicht Aanwinsten MBU Maand: mar-2004 Vakgebiedsbibliotheek: MBU Collectie: MBUBK Auteur : Doyle Derek Titel : Oxford textbook of palliative medicine ed. by Derek Doyle ... [et al.] Plaats : Oxford [etc.] Jaar : Signatuur : MBUBK: AC 01 2004 01 WNU Aanwinstdatum : 12-MAR-04 Auteur : Lodish Harvey Titel : Molecular cell biology Harvey Lodish ... [et al.] Plaats : New York Jaar : Signatuur : MBUBK: AH 01 2004 01 Aanwinstdatum : 19-MAR-04 Titel : EMBASE list of journals indexed ... Plaats : Amsterdam [etc.] Jaar : Signatuur : MBUBK: BA 02 2003 01 Aanwinstdatum : 18-MAR-04 Auteur : Tröhler Ulrich 1943- Titel : "To improve the evidence of medicine" the 18th century British origins of a critical approach Ulrich Plaats : Edinburgh Jaar : Signatuur : MBUBK: BG 2000 01 Aanwinstdatum : 23-MAR-04 Auteur : Lodish Harvey Titel : Molecular cell biology Harvey Lodish ... [et al.] Plaats : New York Jaar : Signatuur : MBUBK: CH 01 2004 01 Aanwinstdatum : 19-MAR-04 Auteur : Greenspan Francis S. Titel : Basic and clinical endocrinology edited by Francis S. Greenspan Plaats : Los Altos, CA

9. Bert Sakmann - Autobiography bert sakmann Autobiography. I was born during the second world war in Stuttgart, the capital of Swebia, as My father, bertold sakmann, was the director of a theatre, the third http://www.nobel.se/medicine/laureates/1991/sakmann-autobio.html

I was born during the second world war in Stuttgart, the capital of Swebia, as the first of two children. My father, Bertold Sakmann, was the director of a theatre, the third son of a physician whose family had lived in southern Germany for several generations. My mother, Annemarie Sakmann, was a physiotherapist and was born in Bangkok, the second child of a Prussian physician who served as doctor to the King of Siam and was the founder of the first hospital in Siam. During the first half of my childhood I grew up in Lindau, on Lake Constance, in a completely rural environment. There I went to elementary school, before returning to Stuttgart where I completed my Abitur at the Wagenburg Gymnasium. My only real interests at school were the physics lessons. At home I spent most of my time designing and building model motor and sailing ships as well as remote control aeroplanes. It was generally assumed that I would become an engineer. In the final year of school however I learned about cybernetics and its possible application to biology. Cybernetics fascinated me, because it seemed to me that living organisms could be understood in engineering terms. Since I could not make up my mind between physics and biology I enrolled at the medical faculty of Munich Technical University . After three years of experimental work on the neurophysiological basis of light adaptation in the cat's visual system I realized that the central nervous system (CNS) was too difficult to comprehend without understanding the synaptic connections more clearly. I went to a course on basic mechanisms of vision in a summer school and I attended a lecture given by

10. Sakmann, Bert sakmann, bert. ( b. June 12, 1942, Stuttgart, Ger From 1969 to 1970 sakmann served as a research assistant in the department of neurophysiology at the Max Planck http://www.britannica.com/nobel/micro/519_58.html

Sakmann, Bert (b. June 12, 1942, Stuttgart, Ger.), German medical doctor and research scientist who in 1991, together with German physicist Erwin Neher , won the Nobel Prize for Physiology or Medicine for research into basic cell function and for their development of the patch-clamp techniquea laboratory method widely used in cell biology and neuroscience to detect electrical currents as small as a trillionth of an ampere through cell membranes. Working together, the two men used the patch-clamp technique to conclusively establish the existence of characteristic sets of ion channels in cell membranessome of which permit the flow of only positive ions, while others pass only negatively charged ions. This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders. These discoveries enabled the development of new and more specific drug therapies. In 1979 Sakmann became a research associate in the Max Planck Institute's membrane biology group. He was made head of the membrane physiology unit in 1983, and he became director of the institute's department of cell physiology two years later.

11. Medicine 1991 for their discoveries concerning the function of single ion channels incells . Erwin Neher, bert sakmann. 1/2 of the prize, 1/2 of the prize. http://www.nobel.se/medicine/laureates/1991/

The Nobel Prize in Physiology or Medicine 1991 "for their discoveries concerning the function of single ion channels in cells" Erwin Neher Bert Sakmann 1/2 of the prize 1/2 of the prize Federal Republic of Germany Federal Republic of Germany Max-Planck-Institut für Biophysikalische Chemie Goettingen, Federal Republic of Germany Max-Planck-Institut für medizinische Forschung Heidelberg, Federal Republic of Germany b. 1944 b. 1942 The Nobel Prize in Physiology or Medicine 1991 Press Release Presentation Speech Erwin Neher ... Other Resources The 1991 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified September 12, 2003 The Official Web Site of The Nobel Foundation

12. Bert Sakmann Winner Of The 1991 Nobel Prize In Medicine bert sakmann, a Nobel Prize Laureate in Physiology and Medicine, at the NobelPrize Internet Archive. bert sakmann. 1991 Nobel Laureate in Medicine http://almaz.com/nobel/medicine/1991b.html

B ERT S AKMANN 1991 Nobel Laureate in Medicine for their discoveries concerning the function of single ion channels in cells. Background Born: 1942 Residence: Germany Affiliation: Max-Planck-Institut für Medizinische Forschung, Heidelberg Featured Internet Links Prize co-recipient: Erwin Neher Search WWW Search The Nobel Prize Internet Archive Nobel News Links Two Germans Win NObel Prize in Medicine for Cell Research Links added by Nobel Internet Archive visitors Max-Planck-Institut für medizinische Forschung Abteilung Zellphysiologie Winner of The Gairdner Foundation Int'l Award Back to The Nobel Prize Internet Archive Literature ... Medicine We always welcome your feedback and comments

13. Bert Sakmann Invented patch clamping. Has a huge and active lab interested in cellular and systems neuroscience. Use patch clamping in slices and intact animals as well as two photon imaging. http://sunny.mpimf-heidelberg.mpg.de/shared/docs/departments/02/index.php3?LANG=

14. Bert Sakmann Winner Of The 1991 Nobel Prize In Medicine bert sakmann, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. bert sakmann. 1991 Nobel Laureate in Medicine http://www.almaz.com/nobel/medicine/1991b.html

B ERT S AKMANN 1991 Nobel Laureate in Medicine for their discoveries concerning the function of single ion channels in cells. Background Born: 1942 Residence: Germany Affiliation: Max-Planck-Institut für Medizinische Forschung, Heidelberg Featured Internet Links Prize co-recipient: Erwin Neher Search WWW Search The Nobel Prize Internet Archive Nobel News Links Two Germans Win NObel Prize in Medicine for Cell Research Links added by Nobel Internet Archive visitors Max-Planck-Institut für medizinische Forschung Abteilung Zellphysiologie Winner of The Gairdner Foundation Int'l Award Back to The Nobel Prize Internet Archive Literature ... Medicine We always welcome your feedback and comments

15. Index Of Nobel Laureates In Medicine Rodbell, Martin, 1994. Ross, Sir Ronald, 1902. Rous, Peyton, 1966. sakmann, bert,1991. Samuelsson, Bengt I. 1982. Schally, Andrew V. 1977. Sharp, Phillip A. 1993. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

16. Books By Bert Sakmann At Walmart.com - Every Day Low Prices Find books written by bert sakmann. Select from 1000's of books at Walmart.com, we have a great selection of highquality merchandise, friendly service and, of course, Every Day Low Prices. Gift http://rdre1.inktomi.com/click?u=http://na.link.decdna.net/n/3532/4200/www.walma

17. Publications SingleChannel Recording, edited by bert sakmann and Erwin Neher http://sun0.mpimf-heidelberg.mpg.de/Publications.html

Publications of the last few years Single-Channel Recording, edited by Bert Sakmann and Erwin Neher. 2nd ed. Plenum Press, New York 1995. ISBN 0-306-44870-X Back to the Abteilung Zellphysiologie home page Last updated: 21 March 2001. This page is maintained by roth@mpimf-heidelberg.mpg.de

18. Sakmann, Bert --  Britannica Student Encyclopedia sakmann, bert Britannica Student Encyclopedia. MLA style sakmann, bert. BritannicaStudent Encyclopedia. 2004. Encyclopædia Britannica Premium Service. http://www.britannica.com/ebi/article?eu=337905&query=max planck&ct=ebi

19. Sakmann, Bert. The American Heritage® Dictionary Of The English Language: Fourt sakmann, bert. The American Heritage® Dictionary of the English LanguageFourth Edition. 2000. 2000. sakmann, bert. SYLLABICATION Sak·mann. http://www.bartleby.com/61/53/S0035350.html

Select Search All Bartleby.com All Reference Columbia Encyclopedia World History Encyclopedia Cultural Literacy World Factbook Columbia Gazetteer American Heritage Coll. Dictionary Roget's Thesauri Roget's II: Thesaurus Roget's Int'l Thesaurus Quotations Bartlett's Quotations Columbia Quotations Simpson's Quotations Respectfully Quoted English Usage Modern Usage American English Fowler's King's English Strunk's Style Mencken's Language Cambridge History The King James Bible Oxford Shakespeare Gray's Anatomy Farmer's Cookbook Post's Etiquette Bulfinch's Mythology Frazer's Golden Bough All Verse Anthologies Dickinson, E. Eliot, T.S. Frost, R. Hopkins, G.M. Keats, J. Lawrence, D.H. Masters, E.L. Sandburg, C. Sassoon, S. Whitman, W. Wordsworth, W. Yeats, W.B. All Nonfiction Harvard Classics American Essays Einstein's Relativity Grant, U.S. Roosevelt, T. Wells's History Presidential Inaugurals All Fiction Shelf of Fiction Ghost Stories Short Stories Shaw, G.B. Stein, G. Stevenson, R.L. Wells, H.G. Reference American Heritage Dictionary Sakkara ... BIBLIOGRAPHIC RECORD The American Heritage Dictionary of the English Language: Fourth Edition.

20. J Physiol -- Abstracts: Ohana And Sakmann 513 (1): 135 Ohana, O. sakmann, B. Download to Citation Manager Ora Ohana and bert sakmann. Abteilung Zellphysiologie, MaxPlanck-Institut für medizinische Forschung, Jahnstraße 29 http://www.jphysiol.org/cgi/content/abstract/513/1/135

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Full Text of this Article PDF Version of this Article Similar articles found in: J Physiol Online PubMed PubMed Citation This Article has been cited by: other online articles Search PubMed for articles by: Ohana, O. Sakmann, B. Download to Citation Manager The Journal of Physiology pp. Transmitter release modulation in nerve terminals of rat neocortical pyramidal cells by intracellular calcium buffers Ora Ohana and Bert Sakmann Dual whole-cell voltage recordings were made from synaptically connected layer 5 (L5) pyramidal neurones in slices of the young (P14-P16) rat neocortex. The Ca buffers BAPTA or EGTA were loaded into the presynaptic neurone via the pipette recording from the presynaptic neurone to examine their effect on the mean and the coefficient of variation (c.v.) of single fibre EPSP amplitudes, referred to as unitary EPSPs. The fast Ca buffer BAPTA reduced unitary EPSP amplitudes in a concentration dependent way. With 0·1 mM BAPTA in the pipette, the mean EPSP amplitude was reduced by 14 ± 2·8 % (mean ± s.e.m., n = 7) compared with control pipette solution, whereas with 1·5 mM BAPTA, the mean EPSP amplitude was reduced by 72 ± 1·5 % (

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