61. MSN Encarta - Stanley B. Prusiner Translate this page Ya eres suscriptor? Inicia una sesión arriba. stanley B. prusiner. Másinformación sobre stanley B. prusiner de, Otras funciones de Encarta. http://es.encarta.msn.com/encyclopedia_1121506125/Stanley_B_Prusiner.html

Principal Mi MSN Hotmail Buscar ... Suscribirse a MSN Encarta Premium Buscar en Encarta Art­culo de suscripci³n MSN Encarta Premium: Consigue este art­culo junto con 41.000 art­culos m¡s, un atlas din¡mico, diccionarios y mucho m¡s por s³lo 29,95 euros/a±o. M¡s informaci³n. Este art­culo s³lo est¡ disponible para los suscriptores de MSN Encarta Premium. ¿Ya eres suscriptor? Inicia una sesi³n arriba. Stanley B. Prusiner Stanley B. Prusiner (1942- ), neur³logo estadounidense ganador, en 1997, del Premio Nobel de Fisiolog­a y Medicina por el descubrimiento de una nueva... ¿Quieres m¡s de Encarta? Suscr­bete hoy y tendr¡s acceso a: M¡s de 41.000 art­culos Diccionario biling¼e Atlas din¡mico M¡s informaci³n sobre Stanley B. Prusiner de Otras funciones de Encarta Buscar en Encarta Stanley B. Prusiner Principal Mi MSN ... Dinero ©2004 Microsoft Corporation. Reservados todos los derechos. Condiciones de uso Declaraci³n de privacidad aprobada por TRUSTe

62. El Escéptico Digital - SEGÚN STANLEY PRUSINER: "LOS PRIONES HAN CAMBIADO EL AB Translate this page NEURODEGENERACIONES” El descubridor del prión causante de la enfermedad de Creutzfeldt-Jakoby premio Nobel de Medicina, stanley B. prusiner, señaló ayer http://digital.el-esceptico.org/leer.php?id=684&autor=135&tema=18

63. Prions it s adopted. . Backgrounder on stanley B. prusiner, MD, UCSF discoverer ofthe prion . aberrations. stanley B prusiner, born May 28, 1942. Address http://www.mad-cow.org/Nobel.html

Mad Cow Home or Best Links Nobel Prize to Prusiner! Full text of the Award Nobel Prize winner sits on FDA panel ... Curriculum vitae Off-Site: Karolinska Institutet award page ... featuring a third-rate 2.7 meg shockwave animation Nobel Prize to Prusiner! STOCKHOLM, Sweden (Reuter) - Stanley Prusiner, a U.S. biochemist whose discovery provided key insights into dementia-related diseases, won the 1997 Nobel Medicine Prize, Sweden's Karolinska Institute said on Monday. The institute said Prusiner's work helped the world to understand more about Alzheimer's and Mad Cow disease through his discovery of the prion, a disease-causing agent like bacteria or viruses. The prion protein can manifest itself as two proteins, one an innocent ``Dr. Jekyll'' character, while the other, dangerous ``Mr Hyde'' protein causes disease and death. The institute said Prusiner solved the riddle of the prion's properties. Prusiner, 55, is professor of biochemistry at the University of California in San Francisco (UCSF). ``Prusiner's discovery provides important insights that may furnish the basis to understand the biological mechanisms underlying other types of dementia-related diseases, for example Alzheimer's disease, and establishes a foundation for drug development and new types of medical treatment strategies,'' it added.

64. Max-Planck-Gesellschaft - Zülch-Preisträger 1997 Translate this page Zülch-Preisträger 1997. Prof. stanley B. prusiner von der Universityof California, School of Medicine, San Francisco/USA (l.) und Prof. http://www.mpg.de/ueberDieGesellschaft/profil/wissenschaftlichePreise/auszeichnu

STARTSEITE Kontakt Presse Links Sitemap FAQs English document.write('Suchen '); Schnellzugriff BioMax GeoMax Help guests scientists Institute MaxPlanckForum Nachwuchsgruppen Pr¤sident Pr¤sidentenkommiss. Research Schools TechMax Veranstaltungen Wissenschaftsmagazin Institute, Projekte und Einrichtungen Forschungsgebiete Forschungs- ergebnisse ... Preistr¤ger 1997 Z¼lch-Preistr¤ger 1997 Z¼lch-Preistr¤ger 1997 Prof. Stanley B. Prusiner von der University of California, School of Medicine, San Francisco/USA (l.) und Prof. Charles Weissmann, Institut f¼r Molekulare Biologie, Universit¤t Z¼rich, Z¼rich/Schweiz (r.) wurden in Anerkennung ihrer hervorragenden Arbeiten auf dem Gebiet der Erforschung ¼bertragbarer spongioformer Encepehalopathien ausgezeichnet. Weiteren Widerstand rief Prusiner hervor, als er die Vermutung ¤uŸerte, daŸ sich die Protein-artigen infekti¶sen Partikel, die er „Prionen“ nannte, gleichermaŸen bei ¼bertragbaren wie vererbbaren Krankheiten finden w¼rden - ein solches dualistisches Verhalten war bis dahin unbekannt -, und daŸ sich Prionen zudem auf eine schwer vorstellbare Weise vervielf¤ltigen: sie wandeln normale Protein-Molek¼le in gef¤hrliche um, indem sie die gutartigen Molek¼le veranlassen, ihre Gestalt zu ver¤ndern. Inzwischen sprechen allerdings viele experimentelle und klinische Daten daf¼r, daŸ die Prionen-Hypothese in allen hier erw¤hnten Bereichen korrekt ist. Prionen sind verantwortlich f¼r ¼bertragbare und vererbte Erkrankungen des ZNS, k¶nnen aber auch sporadische Erkrankungen hervorrufen, an denen weder eine infekti¶se noch eine erbliche Komponente beteiligt ist.

65. NDSU Library: /research/subjects/ag/Scrapie Books.php Author prusiner, stanley B. Title Prion Diseases of humans and animalsPublisher Tavistock/Ellis Horwood, 1993 NDSU does not own this book. http://www.lib.ndsu.nodak.edu/research/subjects/ag/Scrapie Books.php

Home Research Subjects Ag Scrapie and Prion Diseases: Books For more books available in libraries, search the NDSU online catalog . For an extensive database of library catalogs, search WorldCat (NDSU staff and students only) Scrapie Prion Diseases Scrapie Title: Diseases of sheep / edited by W.B. Martin and I.D. Aitken. Edition: 3rd ed. Publisher: Oxford [England] ; Malden, MA, USA : Blackwell Science, 2000. Part VI: Diseases of the nervous system. Scrapie in sheep and goats, and related diseases. NDSU call number: SF968 .D465 2000 Title: Prion diseases / edited by Harry F. Baker and Rosalind M. Ridley ; with a foreword by Stanley B. Prusiner. Publisher: Totowa, N.J. : Humana Press, c1996. NDSU call number: QR201.P737 P74 1996 Title: Prion biology and diseases / edited by Stanley B. Prusiner. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c1999. Part IV. Prion diseases in animals.

66. Medizin-Nobelpreis Geht An Prionenforscher - Auszeichnung Für Den Translate this page Prionenforscher. Auszeichnung für den Amerikaner stanley B. prusiner. DerNobelpreis für Medizin geht an den Amerikaner stanley B. prusiner. http://www.nzz.ch/dossiers/2001/bse/1997.10.07-vm-article0BQ97.html

document.ivwimg.src=document.ivwimg.src+"?r="+escape(document.referrer); Samstag, 5. Juni 2004 Frontseite AKTUELL Kommentar International Wirtschaft Schweiz ... Wetter HINTERGRUND Dossiers Aktuelle Abgeschlossene Netzstoff ... Finanzprodukte SERVICE Veranstaltungen Bildschirmschoner MARKTPLATZ Partnersuche Auktionen Flugtickets Swissguide NZZ-ARCHIV NZZ ab 1993 Recherchedienst ZEITUNG Tagesausgabe NZZ NZZ am Sonntag NZZ-VERLAG Kontakte Abo-Dienst Produkte Online-Werbung ... Mediainformationen NZZ-SITES NZZ Folio NZZ Format NZZ-Gruppe Druckformat ... Artikel versenden Rinderwahnsinn Kasten: Medizin-Nobelpreis geht an Prionenforscher Bezug auch zur Alzheimerforschung Suchen In diesem Dossier Sicht und Stand der Wissenschaft Die neue Variante der Creutzfeldt-Jakob-Krankheit Massnahmen und Folgen Herausgegriffen Netzstoff: Eine Auswahl von Hintergrund-Artikeln zum Thema Internet Spezialthemen: Politische Literatur Kontakt Impressum

67. Nobel Conference® XXXVII stanley B. prusiner 1997 Nobel Prize in Physiology/Medicine Universityof California School of Medicine, San Francisco, Neuroscience http://www.gustavus.edu/events/nobel/archive/2001/participants/prusiner.html

Stanley B. Prusiner 1997 Nobel Prize in Physiology/Medicine University of California School of Medicine, San Francisco Neuroscience researcher Stanley B. Prusiner won the 1997 Nobel Prize in physiology or medicine "for his discovery of prions—a new biological principle of infection." His pioneering work had its genesis in 1972 when he encountered a patient who was dying of a so-called "slow virus" brain infection called Creutzfeldt-Jakob disease (CJD). Prusiner eventually identified an entirely new genre of disease-causing agents—which he named "prions"—that exist normally as cellular proteins but possess an innate capacity to convert their structures into highly stabile conformations resulting in several deadly brain diseases of the dementia type in humans and animals, including CJD, scrapie (a sheep disease), Gertsmann-Sträussler-Scheinker disease, and bovine spongiform encephalopathy (BSE—better known as "mad cow disease"). Download Photos for News/Media: PC or Macintosh 2001 Conference Participants Schedule Resources ... Gustavus Homepage Nobel Conference is a registered trademark of Gustavus Adolphus College.

68. NIH Press Release - Long-Time NIH Grantee Stanley B. Prusiner Wins Nobel Prize - FOR IMMEDIATE RELEASE Monday, October 6, 1997, Marian Emr Natalie Larsen (301)4965751. Long-Time NIH Grantee stanley B. prusiner Wins Nobel Prize. http://www.nih.gov/news/pr/oct97/ninds-06.htm

NATIONAL INSTITUTES OF HEALTH National Institute of Neurological Disorders and Stroke FOR IMMEDIATE RELEASE Monday, October 6, 1997 Marian Emr Natalie Larsen Long-Time NIH Grantee Stanley B. Prusiner Wins Nobel Prize Stanley B. Prusiner, M.D., a long-time grantee of the National Institutes of Health (NIH), is the recipient of the 1997 Nobel Prize in physiology or medicine for his discovery of an unusual class of infectious particles called prions. Prions are believed to be responsible for a group of diseases that include "mad cow" disease. Prusiner, who is professor of neurology, virology, and biochemistry at the University of California, San Francisco (UCSF), has received more than 56 million dollars in research grant support from NIH during the last three decades. "Dr. Prusiner is a pioneer in science and medicine. He introduced a truly new idea to the biology of disease... the idea that a protein can be an infectious agent," says Zach W. Hall, Ph.D., Director of the National Institute of Neurological Disorders and Stroke (NINDS), which has supported Dr. Prusiner since 1975. "His work has turned a once obscure corner of medicine into an important source of new ideas about fundamental biological mechanisms." Dr. Prusiner has received additional funding from the National Institute on Aging, the National Center for Research Resources, and the National Institute of General Medical Sciences, all of which are components of NIH. Dr. Prusiner led the work that uncovered the nature of prions (a term he coined from "

69. Nobel 97 - 3 - NOVEMBRE 1997 stanley B. prusiner PHOTO© Stephen Jaffe / AFP Photo. Avant que stanley prusiner ne http://www.cite-sciences.fr/actu/numeros/N54_nov97/kiosques/html/nobel3.html

SCIENCE ACTUALITES - NOVEMBRE 1997 - Avec l'attribution du prix Nobel de Médecine 1997 à l'Américain Stanley Prusiner, professeur au service de neurologie de l'université de Californie à San Francisco, le comité de l'institut Karolinska de Stockholm a voulu récompenser plus le théoricien courageux qui s'est acharné à défendre ses idées novatrices contre l'assaut général des critiques, que l'auteur de la découverte du prion dont le rôle d'agent infectieux, dans la maladie de Creutzfeld-Jacob et la maladie de la"vache folle", reste encore controversé. Stanley B. Prusiner "Avant que Stanley Prusiner ne s'attaque, dans les années 70, au problème extrêmement difficile posé par ces maladies aujourd'hui appelées "maladies à prions", on n'avait rien de moléculaire à se mettre sous la dent. C'est vraiment lui qui, le premier, à force de travail, à force de batailles déployées pour décrocher des crédits, a ouvert la voie et fait avancer les choses" "Prusiner a eu une idée. Et il l'a défendue contre vents et marées. Il faut savoir qu'au début, on s'est moqué de lui. Son courage et son acharnement sont indiscutablement dignes d'éloge. On peut regretter toutefois que Prusiner ait eu le prix pour lui tout seul, qu'il ne l'ait pas partagé avec des biologistes comme le Suisse Charles Weissmann ou l'épidémiologiste anglais Robert Will qui ont joué aussi un rôle de premier plan dans ce domaine."

70. UK Department Of Microbiology And Immunology - Faculty - Glenn Telling Mastrianni, Piero Parchi, Pierluigi Gambetti, Robert Will, James Ironside, CorneliaHeinrich, Patrick Tremblay, Stephen J. DeArmond and stanley B.prusiner. http://www.mc.uky.edu/microbiology/telling.asp

The Graduate School Application Roster Students ... gtell2@pop.uky.edu Office phone FAX number Glenn Telling Associate Professor Doctorate from Carnegie Mellon University Postdoctoral work at University of California, San Francisco My laboratory is focused on deciphering the molecular mechanisms of prion replication, prion species barriers and prion strains using a combination of molecular biological, biochemical, transgenic and cell biological approaches. The prion diseases are transmissible neurodegenerative disorders that include Creutzfeldt-Jakob disease (CJD) in humans, scrapie of sheep and bovine spongiform encephalopathy (BSE) or 'mad cow disease'. It is now clear that a new variant of CJD (vCJD), which is affecting increasing numbers of young adults and teenagers in the United Kingdom , is the human manifestation of BSE. Unlike conventional infectious agents, prions lack genetic material and are composed largely, if not exclusively of an abnormally folded version of the prion protein (PrP). Much of what we currently understand about the mechanism of prion propagation and the molecular basis of prion strains and species barriers derives from transgenic approaches (Campbell et al., 2000; Telling, 2000). A significant portion of our research effort is geared towards characterizing transgenic mouse models for studying chronic wasting disease (CWD), a highly contagious prion disease of deer and elk in the

71. FRANKFURTER RUNDSCHAU Translate this page vereinfacht ) Gegen heftige Anfeindungen der Infektionsbiologen Der Medizin-Nobelpreisgeht an den US-Neurologen stanley B. prusiner Erklärungsmodell für http://nibis.ni.schule.de/~rs-leer/bse/nobel1.htm

FRANKFURTER RUNDSCHAU Den folgenden Artikel fanden wir in der Frankfurter Rundschau vom 11.10.1997 ( er wurde etwas vereinfacht ) Gegen heftige Anfeindungen der Infektionsbiologen Der Medizin-Nobelpreis geht an den US-Neurologen Stanley B. Prusiner Von Harald Schlatter wissenschaftliche Auszeichnung schon jetzt zuteil wurde - denn bislang ist seine bahnbrechende bewiesen. Ausgangspunkt der Studien Prusiners war eine Patientin, die 1972 an der Creutzfeldt-Jakob-Krankheit (CJK) verstarb. Neben einer spontanen und einer vererbbaren Form dieser Hirnschwammerkrankung existiert auch eine dritte, eine Bereits mehrfach ist es durch unzureichend Erregerhindeutet. Die Suche nach ihm blieb aber erfolglos. Das hatte CJK mit Scrapie gemein, einer Hirnschwammerkrankung, die seit mehr als 200 Jahren vorwiegend unter Schafen grassiert. Scrapie : Wiesen, auf denen eine infizierte Herde geweidet hatte, mieden sie mehrere Jahre. Die besorgniserregende Resistenz des damals oder mit ionisierender Strahlung, die normalerweise das Erbgut absterben, konnten dem Hirnschwammerreger nichts anhaben.

72. Nützliche Adressen Translate this page Report(s) 2001 SPIEGEL. Prof. Dr. stanley B. prusiner, c/o Institute forNeurogenerative Disease, University of California, San Francisco, USA. http://earth.prohosting.com/khdit/BSE/Adressen.html

Zum Informieren und Nachfragen bei Fragen zu BSE und der Creutzfeldt-Jakob-Krankheit (CJD), aber auch bei Fragen zu anderen Lebensmittelskandalen I n d e x : BSE-Experten BSE-Hotlines Bundesregierung Creutzfeldt-Jakob-Krankheit ... Presse Die Heimat dieser Liste, d. h. der Internet-Pfad (URL) zu dieser Liste ist derzeit: http://earth.prohosting.com/khdit/BSE/Adressen.html Creutzfeldt-Jakob-Krankheit: Homepage: http://www.uni-goettingen.de/fb/Med/Neuro/reader.html Creutzfeldt-Jakob- Krankheit Interview mitteilte. Robert-Koch-Institut Nordufer 20, D-13553 Berlin. E-Mail: info@rki.de Homepage: http://www.rki.de/ Creutzfeldt-Jakob- Krankheit CJD-Selbsthilfegruppen Links zu Gruppen in den USA BSE-Hotlines: Bayern Berlin Brandenburg Bremen Bundeslandwirtschaftsministerium Deutscher Bauernverband Hamburg Hessen Mecklenburg-Vorpommern Niedersachsen Schleswig-Holstein Clean Food Campaign (USA). Homepage: http://www.cwwg.org/cleanfact.html FoodWatch (Berlin). D-10119 Berlin. E-Mail: info@foodwatch.de Homepage: http://www.foodwatch.de/ Infos: [ Human BSE Foundation (London).

73. Encyclopedia4U - Stanley B. Prusiner - Encyclopedia Article stanley B. prusiner. This article is licensed under the GNU Free DocumentationLicense. It uses material from the Wikipedia article stanley B. prusiner . http://www.encyclopedia4u.com/s/stanley-b-prusiner.html

ENCYCLOPEDIA U com Lists of articles by category ... Encyclopedia Home Page SEARCH : Stanley B. Prusiner Stanley B. Prusiner, M.D. , a Professor of Neurology and Biochemistry at the University of California, San Francisco . was awarded the Nobel Prize in physiology or medicine in for his discovery of prions a class of infectious self reproducing agents composed of protein. Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. Privacy This article is licensed under the GNU Free Documentation License . It uses material from the Wikipedia article " Stanley B. Prusiner

74. Ärzte Zeitung Online - Beiträge Zum Thema Creutzfeldt-Jacob-Krankheit Translate this page können. Das meint Professor stanley B. prusiner, der für seine Prionenforschungden Medizin-Nobelpreis 1997 erhalten wird. weiter http://www.aerztezeitung.de/medizin/infektionskrankheiten/cjk/default.asp?mode=q

75. ThinkQuest : Library : The Nobel Prize stanley B. prusiner Born in Des Moines, Iowa, he received his medicaldegree in biochemistry from the University of Pennsylvania. http://library.thinkquest.org/TQ0313040/med1997.html

Index Biography The Nobel Prize Our website is intended to teach other students about the Nobel Prize and the importance of working hard to make our world a better place. Visit Site 2003 ThinkQuest USA Want to build a ThinkQuest site? The ThinkQuest site above is one of thousands of educational web sites built by students from around the world. Click here to learn how you can build a ThinkQuest site. Privacy Policy

76. CNN - American Wins Nobel Prize For Medicine - Oct 6, 1997 stanley B. prusiner, a professor at the University of California at San Francisco,discovered prions, an entirely new genre of diseasecausing agents, the http://www.cnn.com/WORLD/9710/06/nobel/

American scientist wins Nobel Prize for medicine His work provides insight into brain diseases October 6, 1997 Web posted at: 8:51 a.m. EDT (1251 GMT) STOCKHOLM, Sweden (CNN) An American biologist won the 1997 Nobel prize for medicine Monday for his discovery of a new class of germ believed responsible for brain-wasting conditions such as "mad cow" disease. Stanley B. Prusiner, a professor at the University of California at San Francisco, discovered prions, "an entirely new genre of disease-causing agents," the Nobel citation from Sweden's Karolinska Institute said. "Prusiner has added prions to the list of well-known infectious agents, including bacteria, viruses, fungi and parasites." Prusiner began his search for prions in 1972, after one of his patients died from dementia resulting from Creutzfeldt-Jakob disease, the human equivalent of "mad cow" disease. After 10 years, he and his team produced a preparation derived from diseased hamsters' brains that contained a single agent he called a prion. His work was greeted with skepticism at first: Unlike known infectious agents, prions contain no genetic material, and are simply proteins. Furthermore, the gene encoding for prions is found in all mammals, including humans.

77. Faculty Publications Gerold SchmittUlms, Kirk C. Hansen, Jialing Liu, Cynthia Cowdrey,Jian Yang, Stephen J. DeArmond, Fred E. Cohen, stanley B. prusiner and Michael http://icarus.med.utoronto.ca/patho/faculty.asp?FacultyID=410

78. The Prion Diseases by stanley B. prusiner. But with the optimism of youth, I forged ahead see Prions, by stanley B. prusiner; SCIENTIFIC AMERICAN, October 1984. http://www.cyber-dyne.com/~tom/prionSP.html

The Prion Diseases Prions, once dismissed as an impossibility, have now gained wide recognition as extraordinary agents that cause a number of infectious, genetic and spontaneous disorders by Stanley B. Prusiner. Fifteen years ago I evoked a good deal of skepticism when I proposed that the infectious agents causing certain degenerative disorders of the central nervous system in animals and, more rarely, in humans might consist of protein and nothing else. At the time, the notion was heretical. Dogma held that the conveyers of transmissible diseases required genetic material, composed of nucleic acid (DNA or RNA), in order to establish an infection in a host. Even viruses, among the simplest microbes, rely on such material to direct synthesis of the proteins needed for survival and replication. Later, many scientists were similarly dubious when my colleagues and I suggested that these "proteinaceous infectious particles"or "prions," as I called the disease-causing agentscould underlie inherited, as well as communicable, diseases. Such dual behavior was then unknown to medical science. And we met resistance again when we concluded that prions (pronounced "pree-ons") multiply in an incredible way; they convert normal protein molecules into dangerous ones simply by inducing the benign molecules to change their shape. Today, however, a wealth of experimental and clinical data has made a convincing case that we are correct on all three counts.

79. Science & Technology At Scientific American.com: The 1997 Nobel Prizes -- The Pa MEDICINE Prion Pioneer. stanley B. prusiner. In a January 1995 ScientificAmerican article, stanley B. prusiner wrote Fifteen years http://www.sciam.com/article.cfm?articleID=00082ED3-9DE8-1C76-9B81809EC588EF21

80. Mad Cows, Cannibals And Prions prusiner, stanley B. Borst, Piet. Classificatie 18 Geneeskunde (UNESCO). 42.30 microbiologie(NBC). prusiner, stanley B. (Pica). Borst, P. (Pica). Prionen (GOO). http://www.kb.nl/perl/av_clt.pl?KBC-COMM=GET&BIBLIO_KEY=AC:156345269&KBC-PREV=do

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