1. George E. Palade, M.D. http://cmm.ucsd.edu/palade

G EORGE E. P ALADE, M.D. Professor of Medicine in Residence(Emeritus) Dean for Scientific Affairs(Emeritus) Address: University of California San Diego School of Medicine - 0602 9500 Gilman Drive La Jolla CA 92093-0602 Telephone: Fax: E-Mail: gpalade@ucsd.edu Publications Research Interests In recent years the work of our laboratory was concentrated on the vascular endothelium, especially the continuous type of endothelium found in the microvasculature of muscles, myocardium and lungs. It led to the identification of plasmalemmal vesicles or caveolae of this type of endothelium as the transcytotic carriers for macromolecules, especially proteins larger than 20A diameter. It also led to the discovery of macromolecular complexes of lipids and proteins involved in targeting and membrane fusion and fission, present in the cytosol or associated with caveolae in the endothelium. Finally, we have been studying the effect of a number of factors, especially the vascular endothelium growth factor (VEGF), on angiogenesis and modifications of the microvasculature of tumors. Biography George Palade received a M.D. from the School of Medicine of the University of Bucharest, Romania; was a member of the faculty of that school until 1945 when he came to the United States for postdoctoral studies. He joined A. Claude at the Rockefeller Institute for Medical Research in 1946 and was appointed assistant professor at Rockefeller in 1948; - progressed from assistant professor to full professor and head of the department until 1973 when he moved to Yale as professor and chair of the Section of Cell Biology. He became a senior investigator and Advisor to the Dean in 1983. In 1990, he moved to UCSD as Professor of Medicine in Residence, and Dean for Scientific Affairs.

2. GEORGE E. PALADE GEORGE E. PALADE. Professor of Cellular and Molecular Medicine in Residence; Dean of Scientific Affairs, School of Medicine, UCSD. Degrees and Awards M.D., University of Bucharest, Romania, 1940. Warren Triennial Prize, 1962. Cavenee and G.E. Palade. 1998. Host microvasculature influence on tumor vascular http://www-bioeng.ucsd.edu/wibe/faculty/palade.html

GEORGE E. PALADE Professor of Cellular and Molecular Medicine in Residence; Dean of Scientific Affairs, School of Medicine, UCSD Degrees and Awards: M.D., University of Bucharest, Romania, 1940. Warren Triennial Prize, 1962. Passano Award (shared with K.R. Porter), 1964. Lasker Award, 1966. T. Duckett Jones Award, 1966. Gairdner Special Award, 1967. Louisa Gross Horwitz Prize (shared with A. Claude and K. R. Porter), 1970. Nobel Prize in Physiology/Medicine (shared with A. Claude and C. deDuve), 1974. Brown-Hazen Award, 1983. Schleiden Medaille, Leopoldina Academy, 1985. Henry Gray Award, 1986. National Medal of Science Award, 1986. Eleven honorary degrees. Research Interests: Membrane interactions in eukaryotic cells. Isolation and characterization of different classes of vesicular carriers from normal cells and cells with perturbed membrane traffic. Current work is focused on the cells of the continuous type of microvascular endothelium (for transcytosis by plasmalemmal vesicles or caveolae), and on hepatocytes (for carriers involved in intracellular and transcellular transport). Selected Publications: W.G. Roberts, J. Delaat, M. Nagane, S. Huang, W.K. Cavenee and G.E. Palade. 1998. Host microvasculature influence on tumor vascular morphology and endothelial gene expression. Amer. J. Pathol. 153(4):1239-1248.

3. George E. Palade, M.D. GEORGE E. PALADE, M.D. VEGF), on angiogenesis and modifications of the microvasculature of tumors. Biography. George Palade received a M.D http://cmm.ucsd.edu/Lab_Pages/palade

G EORGE E. P ALADE, M.D. Professor of Medicine in Residence(Emeritus) Dean for Scientific Affairs(Emeritus) Address: University of California San Diego School of Medicine - 0602 9500 Gilman Drive La Jolla CA 92093-0602 Telephone: Fax: E-Mail: gpalade@ucsd.edu Publications Research Interests In recent years the work of our laboratory was concentrated on the vascular endothelium, especially the continuous type of endothelium found in the microvasculature of muscles, myocardium and lungs. It led to the identification of plasmalemmal vesicles or caveolae of this type of endothelium as the transcytotic carriers for macromolecules, especially proteins larger than 20A diameter. It also led to the discovery of macromolecular complexes of lipids and proteins involved in targeting and membrane fusion and fission, present in the cytosol or associated with caveolae in the endothelium. Finally, we have been studying the effect of a number of factors, especially the vascular endothelium growth factor (VEGF), on angiogenesis and modifications of the microvasculature of tumors. Biography George Palade received a M.D. from the School of Medicine of the University of Bucharest, Romania; was a member of the faculty of that school until 1945 when he came to the United States for postdoctoral studies. He joined A. Claude at the Rockefeller Institute for Medical Research in 1946 and was appointed assistant professor at Rockefeller in 1948; - progressed from assistant professor to full professor and head of the department until 1973 when he moved to Yale as professor and chair of the Section of Cell Biology. He became a senior investigator and Advisor to the Dean in 1983. In 1990, he moved to UCSD as Professor of Medicine in Residence, and Dean for Scientific Affairs.

4. George E. Palade - Autobiography george E. palade Autobiography. I was born in November 1912 in Jassy (Iasi My father, Emil palade, was professor of philosophy and my mother, Constanta Cantemirpalade, was a http://www.nobel.se/medicine/laureates/1974/palade-autobio.html

I was born in November 1912 in Jassy (Iasi), the old capital of Moldavia, the eastern province of Romania. My education was started in that city and was continued through a baccalaureate (continental style) at the "Al Hasdeu" Lyceum in Buzau. My father, Emil Palade, was professor of philosophy and my mother, Constanta Cantemir-Palade, was a teacher. The family environment explains why I acquired early in life great respect for books, scholars and education. My father had hoped I was going to study philosophy at the University, like himself, but I preferred to deal with tangibles and specifics, and - influenced by relatives much closer to my age than he was - I entered the School of Medicine of the University of Bucharest (Romania) in 1930. Delphinus delphi. It was an attempt to understand its structure in terms of the functional adaptation of a mammal to marine life. I graduated in 1940 and, after a short period as an assistant in internal medicine, I went back to Anatomy, since the discrepancy between knowledge possessed by, and expected from, the medical practitioners of that time made me rather uneasy. During the second world war, I served in the medical corps of the Romanian Army, and after the war - encouraged by Grigore Popa, Rainer's successor - I came to the United States in 1946 for further studies. I worked for a few months in the Biology Laboratory of Robert Chambers at

5. Palade, George E. palade, george E., in full george EMIL palade (b. Nov palade received a degree in medicine from the University of Bucharest in 1940 and remained there as a professor http://www.britannica.com/nobel/micro/447_89.html

Palade, George E., in full GEORGE EMIL PALADE (b. Nov. 19, 1912, Iasi, Rom.), Romanian-born American cell biologist who developed tissue-preparation methods, advanced centrifuging techniques, and conducted electron microscopy studies that resulted in the discovery of several cellular structures. With Albert Claude and Christian de Duve he was awarded the Nobel Prize for Physiology or Medicine in 1974. Palade received a degree in medicine from the University of Bucharest in 1940 and remained there as a professor until after World War II. He immigrated to the United States in 1946 and began work at the Rockefeller Institute in New York. Palade performed many studies on the internal organization of such cell structures as mitochondria, chloroplasts, the Golgi apparatus, and others. His most important discovery was that microsomes, bodies formerly thought to be fragments of mitochondria, are actually parts of the endoplasmic reticulum (internal cellular transport system) and have a high ribonucleic acid (RNA) content. They were subsequently named ribosomes. Palade became a naturalized citizen of the United States in 1952 and in 1958 a professor of cytology at Rockefeller Institute, which he left in 1972 to direct studies in cell biology at Yale University Medical School.

6. Medicine 1974 cell . Albert Claude, Christian de Duve, george E. palade. 1/3 of theprize, 1/3 of the prize, 1/3 of the prize. Belgium, Belgium, USA. Université http://www.nobel.se/medicine/laureates/1974/

The Nobel Prize in Physiology or Medicine 1974 "for their discoveries concerning the structural and functional organization of the cell" Albert Claude Christian de Duve George E. Palade 1/3 of the prize 1/3 of the prize 1/3 of the prize Belgium Belgium USA Université Catholique de Louvain Louvain, Belgium Rockefeller University New York, NY, USA Yale University, School of Medicine New Haven, CT, USA b. 1899 d. 1983 b. 1917 b. 1912 (in Iasi, Romania) The Nobel Prize in Physiology or Medicine 1974 Press Release Presentation Speech Educational ... Other Resources The 1974 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified December 18, 2003 The Official Web Site of The Nobel Foundation

7. George E. Palade Winner Of The 1974 Nobel Prize In Medicine george E. palade, a Nobel Prize Laureate in Physiology and Medicine, at the NobelPrize Internet Archive. george E. palade. 1974 Nobel Laureate in Medicine http://almaz.com/nobel/medicine/1974c.html

G EORGE E P ALADE 1974 Nobel Laureate in Medicine for their discoveries concerning the structural and functional organization of the cell. Background Born: 1912 Place of Birth: Iasi, Romania Residence: U.S.A. Affiliation: Yale University School of Medicine, New Haven, CT Featured Internet Links Prize co-recipient: Albert Claude Prize co-recipient: Christian De Duve Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors Photo Winner of The Gairdner Foundation Int'l Award George Emil Palade Biography (submitted by Monty) Back to The Nobel Prize Internet Archive Literature Peace Chemistry ... Medicine We always welcome your feedback and comments

8. George E. Palade Winner Of The 1974 Nobel Prize In Medicine george E. palade, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. george E. palade. 1974 Nobel Laureate in Medicine Winner of The Gairdner Foundation http://www.almaz.com/nobel/medicine/1974c.html

G EORGE E P ALADE 1974 Nobel Laureate in Medicine for their discoveries concerning the structural and functional organization of the cell. Background Born: 1912 Place of Birth: Iasi, Romania Residence: U.S.A. Affiliation: Yale University School of Medicine, New Haven, CT Featured Internet Links Prize co-recipient: Albert Claude Prize co-recipient: Christian De Duve Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors Photo Winner of The Gairdner Foundation Int'l Award George Emil Palade Biography (submitted by Monty) Back to The Nobel Prize Internet Archive Literature Peace Chemistry ... Medicine We always welcome your feedback and comments

9. Index Of Nobel Laureates In Medicine NussleinVolhard, Christiane, 1995. Nurse, Paul M. 2001. Ochoa, Severo, 1959.palade, george E. 1974. Pavlov, Ivan Petrovich, 1904. Porter, Rodney R. 1972. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

10. George E. Palade --  Encyclopædia Britannica palade, george E. Encyclopædia Britannica Article. george E. palade. born Nov. Tocite this page MLA style george E. palade. Encyclopædia Britannica. 2004. http://www.britannica.com/eb/article?eu=59495

11. George Palade, MD Research / Clinical Summary main page. Browse by Name. Department / medical specialty. Research program. Disease / research topic. Fulltext search. Search site Research / Clinical Summary. george http://www.cancer.ucsd.edu/summaries/gpalade.asp

Research (Research / Clinical Summaries) Summaries Main Page Department / Medical Specialty Research Program Disease / Research Topic ... Full-text Search Search site: Research / Clinical Summary George Palade, MD Cancer Biology Program Contact by Email Diseases/Research Topics VEGF In recent years the work of our laboratory was concentrated on the vascular endothelium, especially the continuous type of endothelium found in the microvasculature of muscles, myocardium and lungs. It led to the identification of plasmalemmal vesicles or caveolae of this type of endothelium as the transcytotic carriers for macromolecules, especially proteins larger than 20A diameter. It also led to the discovery of macromolecular complexes of lipids and proteins involved in targeting and membrane fusion and fission, present in the cytosol or associated with caveolae in the endothelium. Finally, we have been studying the effect of a number of factors, especially the vascular endothelium growth factor (VEGF), on angiogenesis and modifications of the microvasculature of tumors. Update Summary via ONcLINE (password required) Click here to request a new or forgotten password Home Events ... Search This site is a service of the Moores UCSD Cancer Center. Comments or questions? Please contact our

12. Palade, George E. palade, george E. (1912). I was born in November 1912 in Jassy (Iasi),the old capital of Moldavia, the eastern province of Romania. http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/P/Palade/Palade.

Palade, George E. I was born in November 1912 in Jassy (Iasi), the old capital of Moldavia, the eastern province of Romania. My education was started in that city and was continued through a baccalaureate (continental style) at the "Al Hasdeu" Lyceum in Buzau. My father, Emil Palade, was professor of philosophy and my mother, Constanta Cantemir-Palade, was a teacher. The family environment explains why I acquired early in life great respect for books, scholars and education. My father had hoped I was going to study philosophy at the University, like himself, but I preferred to deal with tangibles and specifics, and - influenced by relatives much closer to my age than he was - I entered the School of Medicine of the University of Bucharest (Romania) in 1930. Early in my student years I developed a strong interest in basic biomedical sciences by listening to, and speaking with, Francisc Rainer and André Boivin, professors of Anatomy and Biochemistry, respectively. As a result, I started working in the Anatomy laboratory while still in medical school. I went, nonetheless, through six years of hospital training, mostly in internal medicine, but I did the work for my doctorate thesis in microscopic anatomy on a rather unusual topic (for an M.D.): the nephron of the cetacean Delphinus delphi. It was an attempt to understand its structure in terms of the functional adaptation of a mammal to marine life.

13. Themes Geography History History Prize Winners Nobel 1973, Frisch, Karl von Lorenz, Konrad - Tinbergen, Nikolaas. 1974,Claude, Albert - Duve, Christian de - palade, george E. 1975, Baltimore http://www.cartage.org.lb/en/themes/GeogHist/histories/prizewinners/nobelprize/m

Themes History Prize Winners Nobel Prize Year Winners Behring, Emil Adolf von Ross, Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich ... Bárány, Robert The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section Bordet, Jules Krogh, Schack August Steenberg The prize money was allocated to the Special Fund of this prize section Hill, Archibald Vivian Meyerhof, Otto Fritz Banting, Frederick Grant Macleod, John James Richard ... Einthoven, Willem The prize money was allocated to the Special Fund of this prize section Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan ... Domagk, Gerhard The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section Dam, Henrik Carl Peter

14. JCB -- Index By Author: May 1 1972; 53 (2) Okun, Lawrence M. P. palade, george E. Abstract palade, george E. Abstract Phillips, David M. http://www.jcb.org/content/vol53/issue2/aindex.shtml

Home Help Feedback Subscriptions ... Table of Contents Index by Author: May 1 1972; 53 (2) [Table of Contents] A B C ... H I J K L M ... P Q R S T U V W X Y Z A Anderson, S. [Abstract] B Baker, P. F. Brandhorst, Bruce P. [Abstract] C Castle, J. David [Abstract] Chambers, T. C. D D'Monte, B. [Abstract] Daneholt, B. [Abstract] Dumont, James N. E [Abstract] [Abstract] [Abstract] Einstein, Albert B. [Abstract] F Feeney, Lynette [Abstract] G Gilula, Norton B. [Abstract] Goldschneider, Irving [Abstract] Goodman, J. [Abstract] Grey, Robert D. Gross, Nicholas J. [Abstract] H Hackenbrock, Charles R. [Abstract] Houk, J. M. [Abstract] Humphreys, Tom [Abstract] J Jamieson, James D. [Abstract] K Kierszenbaum, A. L. [Abstract] Kirschner, Robert G. [Abstract] Konigsberg, Irwin R. [Abstract] L Lambert, B. [Abstract] Lecount, Thomas S. Lipton, Bruce H. [Abstract] [Abstract] M Manning, Jerry E. Martin, B. J. Mersmann, H. J. [Abstract] Moscona, A. A. [Abstract] N Novikoff, Alex B. [Abstract] Novikoff, Phyllis M. [Abstract] O O'Brien, Thomas W. O'Loughlin, G. T. Okun, Lawrence M. P Palade, George E. [Abstract] Palade, George E. [Abstract] Phillips, David M.

15. George E. Palade Publications george E. palade, MD Selected Publications. 1. palade G. (1975) Intracellularaspects of the process of protein synthesis. Science 189(4200)347358. http://cmm.ucsd.edu/palade/publications.html

George E. Palade, M.D. Selected Publications Palade G. (1975) Intracellular aspects of the process of protein synthesis. Science Entrez Reference Howell KE, Palade GE. (1982) Hepatic Golgi fractions resolved into membrane and content subfractions. J Cell Biol Summary Palade GE. (1983) Membrane biogenesis: an overview. Methods Enzymol :XXIX-LV. Entrez Reference Sztul ES, Howell KE, Palade GE. (1985) Biogenesis of the polymeric IgA receptor in rat hepatocytes. II. Localization of its intracellular forms by cell fractionation studies. J Cell Biol Summary Sztul E, Kaplin A, Saucan L, Palade G. (1991) Protein traffic between distinct plasma membrane domains: isolation and characterization of vesicular carriers involved in transcytosis. Cell Summary Jacobson BS, Schnitzer JE, McCaffery M, Palade GE. (1992) Isolation and partial characterization of the luminal plasmalemma of microvascular endothelium from rat lungs. Eur J Cell Biol Summary Saucan L, Palade GE. (1994) Membrane and secretory proteins are transported from the Golgi complex to the sinusoidal plasmalemma of hepatocytes by distinct vesicular carriers. J Cell Biol Summary Palade GE. (1995) Protein kinesis: the dynamics of protein trafficking and stability.

16. Encyclopedia: George E. Palade Updated Aug 05, 2003. Encyclopedia george E. palade. george Emilpalade (born November 19, 1912) is a Romanianborn cell biologist. http://www.nationmaster.com/encyclopedia/George-E.-Palade

Supporter Benefits Signup Login Sources ... Pies Factoid #48 Former enemies, the Americans and Russians now have a great deal in common - they both lead the world in locking people up Interesting Facts Make your own graph: Hold down Control and click on several. Compare All Top 5 Top 10 Top 20 Top 100 Bottom 100 Bottom 20 Bottom 10 Bottom 5 All (desc) in category: Select Category Agriculture Crime Currency Democracy Economy Education Energy Environment Food Geography Government Health Identification Immigration Internet Labor Language Manufacturing Media Military Mortality People Religion Sports Taxation Transportation Welfare with statistic: view: Correlations Printable graph / table Pie chart Scatterplot with ... * Asterisk means graphable. Added May 21 Mortality stats Multi-users ½ price Catholic stats Top Graphs Richest Most Murderous Most Populous Most Militaristic ... More Stats Categories Agriculture Background Crime Currency ... Welfare Updated: , Encyclopedia : George E. Palade Sponsored links: Sorry, no entry exists for this yet. The Wikipedia article included on this page is licensed under the GFDL Usage implies agreement with terms

17. National Academy Of Sciences - Members palade, george E. University of California, San Diego. Elected to NAS 1961. ScientificDiscipline Cellular and Developmental Biology. Membership Type Member. http://www4.nationalacademies.org/nas/naspub.nsf/(urllinks)/NAS-58N2FT?opendocum

18. National Academy Of Sciences Nurse, Paul. NussleinVolhard, Christiane. Olson, Eric N. Orci, Lelio. palade,george E. Pardee, Arthur B. Penman, Sheldon. Perry, Robert P. Philipson, Lennart. http://www4.nationalacademies.org/nas/naspub.nsf/urllinks/$$Section22?OpenDocume

19. George E. Palade Translate this page Nobelpreis fuer Medizin 1974 (Nobel Prize Medicine 1974) GeorgeE. palade, amerikan. Biochemiker, geb. 12. Nov. 1912. http://www.zuta.de/npmed/palade.htm

Nobelpreis fuer Medizin 1974 (Nobel Prize Medicine 1974) George E. Palade, amerikan. Biochemiker, geb. 12. Nov. 1912

20. Knowledge ª¾ÃѺô "©¬©Ô¼w Palade, George E(mil) (1912.11.19~)" ¤å¥à The summary for this Chinese (Traditional) page contains characters that cannot be correctly displayed in this language/character set. http://www.knowledge.idv.tw/Document.asp?DocumentNo=3515

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