1. George Hitchings George H. Hitchings. Editor s note George H. Hitchings died on February27, 1998, just a few days after this issue was printed.. http://www.washington.edu/alumni/columns/march98/hitchings.html

George H. Hitchings [Editor's note: George H. Hitchings died on February 27, 1998, just a few days after this issue was printed.] George H. Hitchings, '27, knew he'd been considered for the Nobel Prize in medicine. He'd already received many other awards for his basic research on designing drugs, which led to the development of medications for various cancers and bacterial infections, as well as AIDS, herpes, gout, malaria and transplantation. Still, he was surprised when he won. At 83, he thought he was too old to be considered anymore, though he was still hard at work in science and philanthropy, as president of the Burroughs Wellcome Fund in Research Triangle Park, N.C. His only regret was that his first wife could not be by his side when he accepted the prize. Beverly Reimer Hitchings died in 1985, after 52 years of marriage. His second wife, physician Joyce Shaver Hitchings, shared Hitchings' story, as he is now blind, has Alzheimer's disease, and could not be interviewed. "He's still enjoying family, old friends, music. The physcial beauty of Nature has become more vivid," she says. "We live near a lake, which reminds him of Puget Sound and Friday Harbor, where he did research." In September 1988, shortly before the prize announcement, Hitchings had started a whirlwind courtship with Joyce Shaver, 26 years his junior. When the prize was announced the next month, she recalled, "My first thought was, `Oh no, I've lost him to the world.' "

2. George H. Hitchings (Infoplease.com) http://www.infoplease.com/ipa/A0758239.html

HOTWORDS CITE PRINT EMAIL in All Infoplease Almanacs Biographies Dictionary Encyclopedia Home Almanacs Atlas Dictionary ... D-Day Infoplease Tools Periodic Table Conversion Tool Perpetual Calendar Year by Year ... Site Map Also from Infoplease Search Infoplease Info search tips Search Biographies Bio search tips Biography Noteworthy People Deaths ... G - L George H. Hitchings Age: 1988 Nobel Prize winner for pharmaceutical research that led to the creation of drugs to treat lukemia and other diseases of the immune system. Died: Feb. 27, 1998. Sir Francis Harry Hinsley G - L Chris Hitopoulos Related content from HighBeam Research on: George H. Hitchings Two Americans, Briton share medical Nobel. (Gertrude B. Elion, George H. Hitchings, James W. Black) (Science News) MEDICINE'S DR. GEORGE HITCHINGS DIES NOBEL LAUREATE, STATE NATIVE PIONEERED DRUGS.(News)(Obituary) (Seattle Post-Intelligencer (Seattle, WA)) Nobel Prizes in Physiology or Medicine. (United Press International) (Agence France Presse Spanish) SAS Community Learning Center Unveiled; Proceeds From SAS Championship Senior PGA Tournament Support Education in Triangle. (Business Wire) Francisco Ayala elected society president. (Sigma Xi Today).

3. George H. Hitchings - Autobiography george H. hitchings Autobiography. My forebears all came from the United Kingdom. On my father's side, they migrated from London and County Derry in Northern Ireland to Londonderry, New Hampshire . http://www.nobel.se/medicine/laureates/1988/hitchings-autobio.html

My forebears all came from the United Kingdom. On my father's side, they migrated from London and County Derry in Northern Ireland to Londonderry, New Hampshire. When the American Revolution came, they, as loyalists, moved on to Canada. My father, grandfather and great-grandfather were born in St. Andrews, New Brunswick. In 1865, my grandfather, Andrew Hitchings, moved his family to Eureka, California. Andrew was a skilled craftsman in the building of wooden ships, and my father, George Herbert Hitchings, Sr., followed in his footsteps, eventually becoming a marine architect and master builder. On my mother's side, Scottish and English prevailed. The first American was one Thomas Littlejohn from near Edinburgh, who came to the New World about 1735. His descendants, including Shaws, Eldridges and Thomases, moved about in the Maritime Provinces and New England. My maternal grandfather and great-grandfather were descendants of the Matthews family that emigrated twenty-four strong from near Glasgow to Prince Edward Island about 1800. My grandfather, Peter Matthews, married Sara Elizabeth Eldridge, and my mother, Lillian Matthews, was born in Maine. In 1875, my grandfather moved his family across the United States. He, too, was a shipbuilder and settled in Eureka. My mother and father met and were married in Eureka, and my two sisters were born there. About 1897, Peter Matthews established a shipyard in Hoquiam, Washington, to build lumber carriers for the E.K. Wood Lumber Company. The company built several schooners a year. When Peter Matthews died, my father succeeded to the management, which then became Hitchings and Joyce. Later, my father was master builder and supervisor in Bellingham, Washington, and Coos Bay, Oregon, and between times he engaged in marine architecture. He worked in the period between sail and steam and was especially noted for the design of the transition vessel, the steam schooner, which had a wooden hull and was steam propelled.

4. Hitchings, George Herbert george H. hitchings reacting to questions at a press conference after it wasannounced he had won the Nobel Prize for Physiology or Medicine, 1988. http://www.britannica.com/nobel/micro/272_65.html

Hitchings, George Herbert George H. Hitchings reacting to questions at a press conference after it was announced he had won the Nobel Prize for Physiology or Medicine, 1988 UPI/Corbis-Bettmann (b. April 18, 1905, Hoquiam, Wash., U.S.d. Feb. 27, 1998, Chapel Hill, N.C.), American pharmacologist who, along with Gertrude B. Elion and Sir James W. Black , received the Nobel Prize for Physiology or Medicine in 1988 for their development of drugs that became essential in the treatment of several major diseases. Hitchings received his bachelor's and master's degrees from the University of Washington and earned a Ph.D. in biochemistry at Harvard University in 1933. He taught at Harvard until 1939, and in 1942 he joined the Burroughs Wellcome Laboratories, at which he conducted research until his retirement in 1975. Over a span of nearly 40 years, Hitchings worked with Elion, who was first his assistant and then his colleague in research at Burroughs Wellcome. Together they designed a variety of new drugs that achieved their effects by interfering with the replication or other vital functions of specific pathogens (disease-causing agents). In the 1950s they developed thioguanine and 6-mercaptopurine (6MP), which became important treatments for leukemia. In 1957 their alteration of 6MP produced the compound azathioprine, which proved useful in treating severe rheumatoid arthritis and other autoimmune disorders and in suppressing the body's rejection of transplanted organs. Their new drug allopurinol was an effective treatment for gout. Other important drugs that were developed by Hitchings and Elion include pyrimethamine, an antimalarial agent; trimethoprim, a treatment for urinary and respiratory tract infections; and acyclovir, the first effective treatment for viral herpes.

5. Biography-center - Letter H www.kfki.hu/~arthp/bio/h/hackaert/ biograph.html database/hitchcock_a.html. hitchings, george H. www.nobel.se/medicine/laureates/1988/ hitchingsautobio.html http://www.biography-center.com/h.html

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6. George H. Hitchings Winner Of The 1988 Nobel Prize In Medicine george H. hitchings, a Nobel Prize Laureate in Physiology and Medicine,at the Nobel Prize Internet Archive. george H. hitchings. http://almaz.com/nobel/medicine/1988c.html

G EORGE H H ITCHINGS 1988 Nobel Laureate in Medicine for their discoveries of important principles for drug treatment. Background Born: 1905 Residence: U.S.A. Affiliation: Wellcome Research Laboratories, Research Triangle Park, NC Book Store Books on the Pharmaceutical Chemistry Featured Internet Links Prize co-recipient: Sir James W. Black Prize co-recipient: Gertrude B. Elion Official award announcement and background Biography Search WWW Search The Nobel Prize Internet Archive Nobel News Links 3 Share Nobel for Medicine Honoring Drug Discoverers Links added by Nobel Internet Archive visitors Winner of The Gairdner Foundation Int'l Award Back to The Nobel Prize Internet Archive Literature Peace ... Medicine We always welcome your feedback and comments

7. George H. Hitchings Winner Of The 1988 Nobel Prize In Medicine george H. hitchings, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. george H. hitchings. 1988 Nobel Laureate in Medicine http://www.almaz.com/nobel/medicine/1988c.html

G EORGE H H ITCHINGS 1988 Nobel Laureate in Medicine for their discoveries of important principles for drug treatment. Background Born: 1905 Residence: U.S.A. Affiliation: Wellcome Research Laboratories, Research Triangle Park, NC Book Store Books on the Pharmaceutical Chemistry Featured Internet Links Prize co-recipient: Sir James W. Black Prize co-recipient: Gertrude B. Elion Official award announcement and background Biography Search WWW Search The Nobel Prize Internet Archive Nobel News Links 3 Share Nobel for Medicine Honoring Drug Discoverers Links added by Nobel Internet Archive visitors Winner of The Gairdner Foundation Int'l Award Back to The Nobel Prize Internet Archive Literature Peace ... Medicine We always welcome your feedback and comments

8. Index Of Nobel Laureates In Medicine Heymans, Corneille Jean Francois, 1938. Hill, Sir Archibald Vivian, 1922. hitchings,george H. 1988. Hodgkin, Sir Alan Lloyd, 1963. Holley, Robert W. 1968. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

9. Medicine 1988 Sir James W. Black, Gertrude B. Elion, george H. hitchings. 1/3 ofthe prize, 1/3 of the prize, 1/3 of the prize. United Kingdom, USA,USA. http://www.nobel.se/medicine/laureates/1988/

The Nobel Prize in Physiology or Medicine 1988 "for their discoveries of important principles for drug treatment" Sir James W. Black Gertrude B. Elion George H. Hitchings 1/3 of the prize 1/3 of the prize 1/3 of the prize United Kingdom USA USA London University, King's College Hospital Medical School London, United Kingdom Wellcome Research Laboratories Research Triangle Park, NC, USA Wellcome Research Laboratories Research Triangle Park, NC, USA b. 1924 b. 1918 d. 1999 b. 1905 d. 1998 The Nobel Prize in Physiology or Medicine 1988 Press Release Presentation Speech Sir James W. Black ... Banquet Speech The 1988 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified June 30, 2003 The Official Web Site of The Nobel Foundation

10. George H. Hitchings Gertrude B. Elion, george H. hitchings, James W. Black) ( Science News)MEDICINE'S DR. george hitchings DIES NOBEL LAUREATE, STATE NATIVE PIONEERED DRUGS.(News)(Obituary) http://www.infoplease.com/ipa/a0758239.html

HOTWORDS CITE PRINT EMAIL in All Infoplease Almanacs Biographies Dictionary Encyclopedia Home Almanacs Atlas Dictionary ... D-Day Infoplease Tools Periodic Table Conversion Tool Perpetual Calendar Year by Year ... Site Map Also from Infoplease Search Infoplease Info search tips Search Biographies Bio search tips Biography Noteworthy People Deaths ... G - L George H. Hitchings Age: 1988 Nobel Prize winner for pharmaceutical research that led to the creation of drugs to treat lukemia and other diseases of the immune system. Died: Feb. 27, 1998. Sir Francis Harry Hinsley G - L Chris Hitopoulos Related content from HighBeam Research on: George H. Hitchings Two Americans, Briton share medical Nobel. (Gertrude B. Elion, George H. Hitchings, James W. Black) (Science News) MEDICINE'S DR. GEORGE HITCHINGS DIES NOBEL LAUREATE, STATE NATIVE PIONEERED DRUGS.(News)(Obituary) (Seattle Post-Intelligencer (Seattle, WA)) Nobel Prizes in Physiology or Medicine. (United Press International) (Agence France Presse Spanish) SAS Community Learning Center Unveiled; Proceeds From SAS Championship Senior PGA Tournament Support Education in Triangle. (Business Wire) Francisco Ayala elected society president. (Sigma Xi Today).

11. Hitchings, George Herbert --  Encyclopædia Britannica , hitchings, george Herbert (1905–98), US pharmacologist, born in Hoquiam, Wash ,Republicans george H. Bush and Birth Control ( 0035) As a young congressman http://www.britannica.com/eb/article?eu=135998

12. MSN Encarta - Hitchings, George Herbert hitchings, george Herbert ( 19051998), American chemist and Nobel Prize winner, born in Hoquiam, Washington Selected Web Links - george H. hitchings Nobel Foundation http://encarta.msn.com/encyclopedia_761582630/George_Herbert_Hitchings.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Hitchings, George Herbert Hitchings, George Herbert (1905-1998), American chemist and Nobel Prize winner, born in Hoquiam, Washington. He received a Ph.D. degree from Harvard... Multimedia Selected Web Links George H. Hitchings [Nobel Foundation] 1 item Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Hitchings, George Herbert from Other Features from Encarta Search Encarta for Hitchings, George Herbert

13. George H. Hitchings Translate this page Nobelpreis fuer Medizin 1988 (Nobel Prize Medicine 1988) george H. hitchings,amerik. Biochemiker, geb. 18. Apr. 1905, gest. 27. Feb. 1998. http://www.zuta.de/npmed/hitchings.htm

Nobelpreis fuer Medizin 1988 (Nobel Prize Medicine 1988) George H. Hitchings, amerik. Biochemiker, geb. 18. Apr. 1905, gest. 27. Feb. 1998

14. Two Americans, Briton Share Medical Nobel. (Gertrude B. Elion, George HighBeam Research, Free Preview 'Two Americans, Briton share medical Nobel. (Gertrude B. Elion, george H. hitchings, James W. Black)' Full Membership required for unlimited access. http://rdre1.inktomi.com/click?u=http://www.highbeam.com/library/doc0.asp?docid=

15. Hitchings, George Herbert hitchings, george Herbert (1905). US pharmacologist who shared the Nobel Prizefor Physiology or Medicine 1988 with his co-worker Gertrude Elion (1918- ). http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/H/Hitchings/1.ht

Hitchings, George Herbert US pharmacologist who shared the Nobel Prize for Physiology or Medicine 1988 with his co-worker Gertrude Elion (1918- ). His work was on anticancer agents, and immunosuppressive drugs and antibiotics that were of vital importance in the growing surgical field of transplantation. Hitchings was born in Hoquiam, Washington, and educated at the University of Washington and at Harvard. In 1942 he joined the biochemical research laboratory of Burroughs Wellcome, where he was joined two years later by Elion. Hitchings rose to vice president of the company 1967. Hitchings and Elion started to synthesize compounds that inhibited bacteria from producing DNA and therefore from multiplying, in the hope that these compounds could be used to prevent the rapid growth of cancer cells. They investigated particularly the chemistry of purines and pyrimidines, two groups of chemicals that are involved with DNA synthesis. Their work lead to the production of clinically significant anticancer drugs as well as drugs against malaria, for the treatment of gout and kidney stones, and also drugs that suppressed the normal immune reactions of the body. In the 1970s, Hitchings and Elion's research produced an antiviral compound, acyclovir, active against the herpes virus, which preceded the development by Burroughs Wellcome of AZT, the anti-AIDS compound.

16. Index For Surnames Beginning With H (Descendancy Pages) Program to export GEDCOM file to HTML Back to Main Page. HALL, george H (b. 1901) , 1887) , ( HILL)) hitchings, Richard , ( hitchings) HOLDING, Michael (b http://www.the-briant-family.com/familytree/myhtmlfiles/h_h.html

17. Hitchings, George H. Translate this page hitchings, george H. (1905-1998). Chimiste américain (Hoquiam, Washington,1905 — Chapel Hill, Caroline du Nord, 1998). Titulaire http://www.cartage.org.lb/fr/themes/Biographies/mainbiographie/H/Hitchings/Hitch

Hitchings, George H. Chimiste américain (Hoquiam, Washington, 1905 — Chapel Hill, Caroline du Nord, 1998). Titulaire d'un doctorat en biochimie obtenu à l'université de Harvard (1933), George H. Hitchings travailla de 1942 à 1984, pour les laboratoires pharmaceutiques Burroughs Wellcome Co, où Gertrude Belle Elion vint le rejoindre dès 1943 Il partagea le prix Nobel 1988 de médecine ou physiologie avec sa collaboratrice, pour leur découvertes de nombreux médicaments aujourd'hui considérés comme essentiels dans le traitement de nombreuses pathologies, comme la cardiopathie, la leucémie, l'ulcère gastrique, le paludisme et la goutte. Hitchings et Gertrude Elion découvrirent en outre l'acyclovir, un médicament utilisé contre l'herpès. Ils partagèrent ce prix Nobel avec le pharmacologue britannique James Whyte Black, cité pour sa découverte de l'effet des bêtabloquants dans le traitement de l'insuffisance cardiaque et de l'hypertension, et de celui des antagonistes du récepteur H-2 dans le traitement des ulcères

18. MSN Encarta - Hitchings, George Herbert Multimedia. Selected Web Links. , george H. hitchings Nobel Foundation.1 item. Want more Encarta? Become a subscriber today and gain access to http://encarta.msn.com/encyclopedia_761582630/Hitchings_George_Herbert.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Hitchings, George Herbert Hitchings, George Herbert (1905-1998), American chemist and Nobel Prize winner, born in Hoquiam, Washington. He received a Ph.D. degree from Harvard... Multimedia Selected Web Links George H. Hitchings [Nobel Foundation] 1 item Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Hitchings, George Herbert from Other Features from Encarta Search Encarta for Hitchings, George Herbert

19. MSN Encarta - Search Results - Herbert George hitchings, george Herbert (19051998), American chemist and Nobel Prize winner 4.george Herbert Palmer Wells, H(erbert) G(eorge) (1866-1946), English author and http://encarta.msn.com/Herbert_George.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Encarta Search results for "Herbert George" Page of 2 next Exclusively for MSN Encarta Premium Subscribers Herbert, George Article—Encarta Encyclopedia Herbert, George (1593-1633), English poet of the metaphysical school. He was born in Wales and educated at the University of Cambridge. He was made... related items English Literature quotations The Collar George Herbert Hitchings Article—Encarta Encyclopedia Hitchings, George Herbert (1905-1998), American chemist and Nobel Prize winner, born in Hoquiam, Washington. He received a Ph.D. degree from Harvard... George Herbert Mead Article—Encarta Encyclopedia Mead, George Herbert (1863-1931), American pragmatist, philosopher and social psychologist, born in South Hadley, Massachusetts. Educated at Oberlin... George Herbert Palmer Article—Encarta Encyclopedia Found in the Palmer, Alice Elvira Freeman article H. G. Wells

20. Biografia De Hitchings, George H. Translate this page hitchings, george H. (Hoquiam, 1905-Chapel Hill, 1998) Médico estadounidense.Especialista en bioquímica y farmacología, estudió http://www.biografiasyvidas.com/biografia/h/hitchings.htm

Inicio Buscador Utilidades Recomendar sitio Enlaces Hitchings, George H. (Hoquiam, 1905-Chapel Hill, 1998) Médico estadounidense. Especialista en bioquímica y farmacología, estudió las diferencias metabólicas entre la síntesis nuclear de las células normales y la de las cancerosas. Como consecuencia de estos trabajos, descubrió diversos fármacos para la leucemia, la malaria y otras enfermedades. En 1988 obtuvo el premio Nobel de medicina y fisiología en 1988, junto con Gertrud B. Elion y James W. Black, y en 1989 fue premio Internacional de Medicina Albert Schweitzer. Inicio Buscador Recomendar sitio

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