1. Leland H Hartwell - Wikipedia Skrivarvänlig version Förbehåll. Ej inloggad. Logga in Hjälp. Leland H Hartwell. Leland H Hartwell. Född 1939. Amerikansk Nobelpristagare i fysiologi eller medicin år 2001. http://sv.wikipedia.org/wiki/Leland_H._Hartwell

Leland H Hartwell Från Wikipedia, den fria encyklopedin. (Omdirigerad från Leland H. Hartwell Leland H Hartwell . Född . Amerikansk Nobelpristagare i fysiologi eller medicin år . Han tilldelades priset för sina " upptäckter rörande kontrollen av cellcykeln ". Han delade priset med engelsmännen Tim Hunt och Sir Paul Nurse Hartwell doktorsexamen vid Massachusetts Institute of Technology blev han professor vid University of Washington. Från är han President och Director vid Fred Hutchinson Cancer Research Center. Cellerna i kroppen har alla uppstått genom delning från en enda cell, den befruktade äggcellen. Även hos vuxna delar sig ständigt en enorm mängd celler för att ersätta de som dör. För att en cell ska kunna dela sig måste den tillväxa i storlek, kopiera sin arvsmassa och exakt fördela den till dottercellerna. Dessa processer samordnas i den s k cellcykeln Leland Hartwell upptäckte en av en klass gener som kontrollerar cellcykeln. En av dessa gener har en central roll för att sätta igång varje ny cellcykel och kallas därför "start". Hartwell införde också begreppet kontrollstationer ("checkpoints") som innebär att cellcykeln stannar upp när cellens DNA utsätts för skada. Syftet är att arvsmassan ska hinna repareras innan cellen går vidare till nästa fas i cellcykeln. Paul Nurse identifierade en av nyckelkomponenterna i kontrollen av cellcykeln, CDK (cyklinberoende kinas). Han visade att CDK har bevarat sin funktion genom evolutionen. CDK driver cellcykeln genom att kemiskt påverka (fosforylera) andra proteiner.

2. Leland H. Hartwell - Wikipedia, The Free Encyclopedia Printable version Disclaimers. Not logged in Log in Help. Leland H.Hartwell. From Wikipedia, the free encyclopedia. Leland H. Hartwell http://en.wikipedia.org/wiki/Leland_H._Hartwell

Leland H. Hartwell From Wikipedia, the free encyclopedia. Leland H. Hartwell (born October 30 , in Los Angeles California ) is president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington He won the Nobel Prize in physiology or medicine for his understanding of the cell cycle through years of studying yeast This article is a stub . You can help Wikipedia by expanding it Categories Nobel Prize in Physiology or Medicine winners Views Article Discussion Edit History Personal tools Log in Navigation Main Page Community portal Current events Recent changes ... Donations Search Toolbox What links here Related changes Special pages This page was last modified 21:20, 2 Jun 2004. All text is available under the terms of the GNU Free Documentation License (see for details). About Wikipedia

3. Leland H Hartwell Textbooks Textbooks & Books Price Comparison - Direct Textbook Leland H Hartwell Textbooks. Genetics From Genes to Genomes w/ GeneticsFrom Genes to Genomes CDROM Hardcover - Show all editions et. al. http://www.directtextbook.com/author/leland-h-hartwell

Search by ISBN, Title, Author, Keyword, or Advanced Leland H Hartwell Textbooks Genetics: From Genes to Genomes w/ Genetics: From Genes to Genomes CD-ROM Hardcover - Show all editions et. al. Leland H. Hartwell , 23 September, 1999 McGraw-Hill Science/Engineering/Math List Price: $137.05 Customer Reviews: ISBN: 0072359935 The Harvey Lectures Series 90 Paperback - Show all editions Ronald M. Evans Christine Guthrie Leland H. Hartwell ... Robert Tjian , 12 July, 1996 John Wiley and Sons List Price: $132.00 ISBN: 0471146226 Love Us? Bookmark Us or Link to Us Don't Love Us? Help Us Improve Home Browse Bookstores ... LD Web Design Company Textbooks Subjects Architecture Textbooks Business Textbooks Business Textbooks Computer Textbooks ... Sell Textbooks Online Get the best prices when selling your used textbooks online by comparing buyback companies. Your Book's ISBN Subscribe to Our Newsletter Be the first to hear about coupons, sales, and other money saving ideas. Your Email Address

4. Leland H. Hartwell topics.practical.org. Leland H. Hartwell. Genetics From Genes toGenomes w/ Genetics From Genes to Genomes CDROM. Genetics From http://topics.practical.org/browse/Leland_H._Hartwell

topics.practical.org Leland H. Hartwell Genetics: From Genes to Genomes w/ Genetics: From Genes to Genomes CD-ROM et. al. Leland H. Hartwell Science/Mathematics Science ... Outlet

5. Leland H. Hartwell Toys Games. Click Here. Encyclopedia. Main Page See live article,Leland H. Hartwell. Leland H. Hartwell (born October 30 1939, in http://www.sciencedaily.com/encyclopedia/leland_h__hartwell

Match: sort by: relevance date Free Services Subscribe by email RSS newsfeeds PDA-friendly format loc="/images/" A A A Find Jobs In: Healthcare Engineering Accounting College Contract / Freelance Customer Service Diversity Engineering Executive Healthcare Hospitality Human Resources Information Tech International Manufacturing Nonprofit Retail All Jobs by Job Type All Jobs by Industry Relocating? Visit: Moving Resources Moving Companies Mortgage Information Mortgage Calculator Real Estate Lookup Front Page Today's Digest Week in Review Email Updates ... Outdoor Living Encyclopedia Main Page See live article Leland H. Hartwell Leland H. Hartwell (born October 30 , in Los Angeles California ) is president and director of the Fred Hutchinson Cancer Research Center. He won the Nobel Prize in physiology or medicine for his understanding of the cell cycle through years of studying yeast This article is a stub. You can help Wikipedia by expanding it. Note: The original source of this article can be found on the main Wikipedia Web site. This article is licensed under the GNU Free Documentation License , which means that you can copy and modify it as long as the entire work (including additions) remains under this license.

6. Leland H. Hartwell - Autobiography leland H. hartwell Autobiography. I don't remember much about my early childhood. I am told that before I began school, my older cousin would return from her school and teach me what she had learned. Educational. Illustrated Presentation. leland H. hartwell. Autobiography. Curriculum Vitae http://www.nobel.se/medicine/laureates/2001/hartwell-autobio.html

California Institute of Technology . This was my next major break. I took the entrance exams and was admitted into the sophomore class. Howard Temin and Bob Edgar. Another feature of the Cal Tech undergraduate education was the opportunity to take credits as reading which I did most quarters, reading the original literature in phage genetics and gene regulation. I graduated in 1961 and went to MIT for graduate school. I had decided that I wanted to work on gene regulation and I knew of only two prominent labs in the US, Arthur Pardee at Berkeley , and Boris Magasanik, at MIT. I visited Arthur Pardee at Berkeley and he was not encouraging so I went to MIT. Being a graduate student at MIT was great fun and very intense. Boris Magasanik would come through the lab each afternoon and stop at each desk to discuss the previous day's results. I wanted a new result each day so that set quite a pace! I was there only about two and a half years when Boris came to me and said that I had essentially finished my thesis but since no one could leave that soon I would have to stay another year. By this time had published their famous work on the lac operon and I figured that gene regulation was pretty well understood. I thought it appropriate to do my postdoctoral work on something much less well understood and I decided to work on the control of cell growth. Going to the literature again, I was most impressed with the work coming out of

7. Medicine 2001 Medicine 2001. for their discoveries of key regulators of the cellcycle . leland H. hartwell, R. Timothy (Tim) Hunt, Sir Paul M. Nurse. http://www.nobel.se/medicine/laureates/2001/

The Nobel Prize in Physiology or Medicine 2001 "for their discoveries of key regulators of the cell cycle" Leland H. Hartwell R. Timothy (Tim) Hunt Sir Paul M. Nurse 1/3 of the prize 1/3 of the prize 1/3 of the prize USA United Kingdom United Kingdom Fred Hutchinson Cancer Research Center Seattle, WA, USA Imperial Cancer Research Fund London, United Kingdom Imperial Cancer Research Fund London, United Kingdom b. 1939 b. 1943 b. 1949 The Nobel Prize in Physiology or Medicine 2001 Press Release Presentation Speech Educational ... Other Resources The 2001 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified December 10, 2003 The Official Web Site of The Nobel Foundation

8. COS Expertise Profile Fred Hutchinson Cancer Research Center. leland H. hartwell. Fred Hutchinson Cancer Research Center Individual Expertise profile of leland H. hartwell, Copyright leland H. hartwell. © http://myprofile.cos.com/hartwell46

Fred Hutchinson Cancer Research Center Leland H. Hartwell Fred Hutchinson Cancer Research Center Human Biology Division University of Washington College of Arts and Sciences Genetics Professor Appointed: 1973 Mailing Address Fred Hutchinson Cancer Research Center 1100 Fairview Avenue N., D1-060 PO Box 19024 Seattle, Washington 98109-1024 United States Contact Information Phone: (206) 667-5670 Fax: (206) 667-5268 lhartwel@fhcrc.org Qualifications Ph.D., Massachusetts Institute of Technology, 1964 Expertise and Research Interests Keywords COS Keywords: Genetics; Cancer Biology; Evolution Additional Terms: Maintenance and Expression of Genetic Variation in Yeast Publications Hartman JL; Garvik B; Hartwell L. Principles for the Buffering of Genetic Variation. Science. 291: 1001-1004, 9 Feb 2001 Simon JA, Szankasi P, Nguyen DK, Ludlow C, Dunstan HM, Roberts CJ, Jensen EL, Hartwell LH, Friend SH. Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Research. 60(2): 328-33, Jan 2000 Hartwell, L.H., Hopfield, J.J., Leibler, S., Murray, A.W.. From molecular to modular cell Biology. Nature 402 supplement. 6761: C47-C52, 1999

9. Medicine-Worldwide: Hartwell - Hunt - Nurse Über uns. Biographie. leland H. hartwell R. Timothy ("Tim") Hunt leland H. hartwell. Neurologe. leland H. hartwell * 30. Oktober 1939 in den USA http://www.m-ww.de/persoenlichkeiten/hartwell_hunt_nurse.html

Sie befinden sich hier: startseite persoenlichkeiten Medizingeschichte H istorisches zur Harnschau M eilensteine der Medizingeschichte ... Über uns Biographie Kapitelübersicht: Leland H. Hartwell R. Timothy ("Tim") Hunt Sir Paul M. Nurse Leland H. Hartwell Neurologe Leland H. Hartwell * 30. Oktober 1939 in den USA R. Timothy ("Tim") Hunt Biochemiker * 19. Februar 1943 in England Sir Paul M. Nurse Biologe * 25. Januar 1949 in England Die drei Wissenschaftler, Leland Hartwell, Timothy Hunt und Paul Nurse, sind die Inhaber des 100. Nobelpreises für Medizin im Jahre 2001, der traditionsgemäß am 10. Dezember, dem Todestag des Preisstifters Alfred Nobel (1833-1896) in Stockholm verliehen wird. Den 1. Nobelpreis für Medizin hatte Emil von Behring (1854-1917) 1901 für seine Leistungen auf dem Gebiet der Serumtherapie der Diphtherie erhalten. Die drei diesjährigen Wissenschaftler erhielten den Preis für die Erforschung der molekularen und biochemischen Ursprünge bei der Zellteilung. "Mit ihren Erkenntnissen haben die Forscher wichtige Grundlagen für die Bekämpfung von Tumoren gelegt", erklärte das Stockholmer Karolinska Institut zur Begründung. Die Nobelpreisträger hatten in den 1970er und 80er Jahren die entscheidenden Komponenten des Zellzyklus der Zellteilung in genetisch verschiedene Abschnitte aufgedeckt. R. Timothy Hunt

10. Sigma Xi: The Scientific Research Society: Leland H. Hartwell Common Wealth ». hartwell. leland H. hartwell. 1994 Common Wealth Award for Science and Invention. leland H. hartwell is widely recognized as a pioneer in the field of yeastgenetics http://www.sigmaxi.org/programs/prizes/common.hartwell.shtml

Overview Diversity Education Ethics ... Common Wealth Search: Site Map Home Common Wealth Leland H. Hartwell 1994 Common Wealth Award for Science and Invention Back to top

11. HARTWELL From Yeast Cell Division to Human Cancer The Unity of Biology. leland H. hartwell, Ph.D. Mellon Prize Lecturer. leland H. hartwell, Ph.D., is president and director of the http://www.science2001.pitt.edu/plenary/hartwell.htm

From Yeast Cell Division to Human Cancer: The Unity of Biology Leland H. Hartwell, Ph.D. Mellon Prize Lecturer Leland H. Hartwell, Ph.D., is president and director of the Fred Hutchinson Cancer Research Center and professor of genetics at the University of Washington. His work over the last 30 years, using yeast as a model organism, forms the foundation upon which today's detailed knowledge of the molecular mechanisms controlling the cell division cycle in nucleated cells rests. Dr. Hartwell's discovery of genes regulating the orderly progression of the cell cycle has had a major influence on our understanding of cancer and the therapeutic strategies used to treat diseases caused by uncontrolled cell growth. Last Plenary Home Next

12. Leland H. Hartwell Winner Of The 2001 Nobel Prize In Physiology Or Medicine leland H. hartwell, the 2001 Nobel Prize Laureate in Physiology or Medicine,at the Nobel Prize Internet Archive. leland H. hartwell. http://almaz.com/nobel/medicine/2001a.html

L ELAND H. H ARTWELL Nobel Laureate in Physiology or Medicine for their discoveries of "key regulators of the cell cycle." Background Born: October 30, 1939 Place of birth: Los Angeles, CA, USA Residence: U.S.A. Affiliation: Fred Hutchinson Cancer Research Center Address: Fred Hutchinson Cancer Research Center University of Washington, Seattle 1100 Fairview Ave N; D1-060 Seattle, WA 98109 Telephone: (206) 667-5670 FAX: (206) 667-5268 E-mail: lhartwel@fhcrc.org Education: California Institute of Technology , B.S. 1961 Massachusetts Institute of Technology , Ph.D. 1964 Book Store Genomic Instability and Immortality in Cancer (Pezcoller Foundation Symposia, 8) The Harvey Lectures Series 90 Genetics: From Genes to Genomes Solutions Manual/Study Guide t/a Genetics: From Genes to Genomes ... Books on Regulators of the Cell Cycle Featured Internet Links Prize co-recipient: R. Timothy Hunt Prize co-recipient: Paul M. Nurse PubMedline search results for this laureate Web Page at Fred Hutchinson Cancer Research Center ... Official award announcement and background Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors CNN story Fred Hutchinson Genomic Instability and Immortality in Cancer (Pezcoller Foundation Symposia, 8) - find the lowest price

13. Index Of Nobel Laureates In Medicine Guillemin, Roger, 1977. Gullstrand, Allvar, 1911. Hartline, Haldan Keffer, 1967.hartwell, leland H. 2001. Hench, Philip Showalter, 1950. Hershey, Alfred D. 1969. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

14. Leland H. Hartwell Winner Of The 2001 Nobel Prize In Physiology Or Medicine leland H. hartwell, the 2001 Nobel Prize Laureate in Physiology or Medicine, at the Nobel Prize Internet Archive. 2001 Nobel Laureate Visits IMCB , Professor leland H. hartwell( submitted by Davis Brown http://www.almaz.com/nobel/medicine/2001a.html

L ELAND H. H ARTWELL Nobel Laureate in Physiology or Medicine for their discoveries of "key regulators of the cell cycle." Background Born: October 30, 1939 Place of birth: Los Angeles, CA, USA Residence: U.S.A. Affiliation: Fred Hutchinson Cancer Research Center Address: Fred Hutchinson Cancer Research Center University of Washington, Seattle 1100 Fairview Ave N; D1-060 Seattle, WA 98109 Telephone: (206) 667-5670 FAX: (206) 667-5268 E-mail: lhartwel@fhcrc.org Education: California Institute of Technology , B.S. 1961 Massachusetts Institute of Technology , Ph.D. 1964 Book Store Genomic Instability and Immortality in Cancer (Pezcoller Foundation Symposia, 8) The Harvey Lectures Series 90 Genetics: From Genes to Genomes Solutions Manual/Study Guide t/a Genetics: From Genes to Genomes ... Books on Regulators of the Cell Cycle Featured Internet Links Prize co-recipient: R. Timothy Hunt Prize co-recipient: Paul M. Nurse PubMedline search results for this laureate Web Page at Fred Hutchinson Cancer Research Center ... Official award announcement and background Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors CNN story Fred Hutchinson Genomic Instability and Immortality in Cancer (Pezcoller Foundation Symposia, 8) - find the lowest price

15. Hartwell, Leland H. hartwell, leland H. (1939). leland H. hartwell, born October 30, 1939Address Fred Hutchinson Cancer Research Center, 1100 Fairview http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/H/Hartwell/Hartw

Hartwell, Leland H. Leland H. Hartwell, born October 30, 1939 Address: Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, D1-060, Seattle, WA 98109-1024, USA Academic Education and Appointments: 1961 B.S. California Institute of Technology 1964 Ph.D. Massachusetts Institute of Technology 1965-68 Associate Professor, University of California 1997 President and Director, Fred Huthcinson Cancer Research Center Selected Honours and Awards: 1987 Member of the US National Academy of Sciences 1991 General Motors Sloan Award 1992 Gairdner Foundation International Award 1994 Genetics Society of America Medal 1998 The Albert Lasker Basic Medical Research Award

16. MSN Encarta - Hartwell, Leland H. Already a subscriber? Sign in above. hartwell, leland H. hartwell Find moreabout hartwell, leland H. from, Other Features from Encarta. Search http://encarta.msn.com/encyclopedia_701505582/Hartwell_Leland_H.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Hartwell, Leland H. Hartwell, Leland H. (1939- ), American geneticist and cowinner of the 2001 Nobel Prize in physiology or medicine for discoveries about key regulators... Related Items Nobel Prize cowinners table of Nobel Prize winners 4 items Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Hartwell, Leland H. from Other Features from Encarta Search Encarta for Hartwell, Leland H.

17. Leland Hartwell leland hartwell. Office Phone ( 206) 6675670, Lab Phone (206) 667-6445 Fax (206) 667-5268 Jensen, E.L., hartwell, L.H., Friend, S.H http://www.gs.washington.edu/faculty/hartwell.htm

Leland Hartwell Office Phone: Lab Phone: Fax: Office Location: Fred Hutchinson Cancer Research Center, D1-060, Box 358080 Email: lhartwel @fhcrc.org Laboratory Research: Selected Publications: Simon JA; Szankasi P; Nguyen DK; Ludlow C; Dunstan HM; Roberts CJ; Jensen EL; Hartwell LH; Friend SH. Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae.. Cancer Res. 60(2): 328-33, 15 2000 Simon, J.A., Szankaski, P., Nguyen, D.K., Ludlow, C, Dunstan, H.M., Roberts, C.J., Jensen, E.L., Hartwell, L.H., Friend, S.H.. Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Research. 60(2): 328-333, 2000 Hartwell, L.H., Hopfield, J.J., Leibler, S., Murray, A.W.. From molecular to modular cell Biology. Nature 402 supplement. 6761: C47-C52, 1999 Marton MJ, DeRisi JL, Bennett HA, Iyer VR, Meyer MR, Roberts CJ, Stoughton R, Burchard J, Slade D, Dai H, Bassett DE Jr, Hartwell LH, Brown PO, Friend SH. Drug target validation and identification of secondary drug target effects using DNA microarrays. Nature Medicine. 4(11): 1293-301, Nov 1998 Paulovich AG, Armour CD, Hartwell LH. The Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 genes are required for tolerating irreparable, ultraviolet-induced DNA damage. Genetics. 150(1): 75-93, Sep 1998

18. Leland H. Hartwell --  Britannica Concise Encyclopedia Online Article Britannica Concise Encyclopedia, hartwell, leland H. Britannica Concise. MLAstyle leland H. hartwell. Britannica Concise Encyclopedia. 2004. http://concise.britannica.com/ebc/article?eu=410004

19. Studies On The Induction Of Histidase In Bacillus Subtilis Studies on the induction of histidase in Bacillus subtilis hdl0018.mit.theses/196415 hartwell, leland H leland H hartwell http://rdre1.inktomi.com/click?u=http://theses.mit.edu:80/Dienst/UI/2.0/Describe

20. HARTWELL, LELAND H. - CIRS hartwell, leland H. Email lhartwel@fhcrc.org President and Director of thethe Fred Hutchcinson Cancer Research Center, Seattle, WA, USA, Professor of http://www.cirs-tm.org/Chercheurs/chercheurs1.php?id=373

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