1. Paul Greengard - Wikipedia Skrivarvänlig version Förbehåll. Ej inloggad. Logga in Hjälp. Paul Greengard. Paul Greengard. Född i New York City 1925. Amerikansk Nobelpristagare i fysiologi eller medicin år 2000. Paul Greengard, upptäckte hur dopamin och en rad andra signalsubstanser utövar sina effekter i nervsystemet http://sv.wikipedia.org/wiki/Paul_Greengard

Paul Greengard Från Wikipedia, den fria encyklopedin. Paul Greengard . Född i New York City . Amerikansk Nobelpristagare i fysiologi eller medicin år . Han tilldelades priset för sina " upptäckter rörande signalsubstanser i nervsystemet ". Han delade priset med sin landsman Eric R Kandel och svensken Arvid Carlsson Signalerna från en nervcell till en annan överförs med hjälp av olika signalsubstanser . Signalöverföringen sker i speciella kontaktpunkter, synapser . En enda nervcell kan ha tusentals kontaktpunkter med andra nervceller. Arvid Carlsson, har upptäckt att dopamin är en sådan signalsubstans i hjärnan och att dopamin har stor betydelse för kontroll av våra rörelser. Hans forskningsrön ledde i sin tur till insikten att Parkinsons sjukdom orsakas av dopaminbrist i vissa delar av hjärnan och till att man kunde få fram ett effektivt läkemedel (L-dopa) mot denna sjukdom. Paul Greengard, upptäckte hur dopamin och en rad andra signalsubstanser utövar sina effekter i nervsystemet. Signalsubstanserna påverkar först en receptor på cellens yta. Det utlöser en kaskad av reaktioner som påverkar vissa "nyckelproteiner" som i sin tur reglerar olika funktioner i cellen. Proteinernas form och funktion förändras genom att fosfatgrupper tillförs (fosforylering) eller tas bort (defosforylering). Genom denna mekanism kan signalsubstanser överföra sina budskap mellan nervceller. Eric Kandel,upptäckte sedan hur synapsernas effektivitet kan förändras och med vilka molekylära mekanismer detta sker. Han visade att synapsernas funktion är central för inlärning och minne. För uppkomsten av en form av korttidsminne spelar proteinfosforylering i synapsen en viktig roll. För att ett långtidsminne ska uppstå krävs dessutom nybildning av proteiner som bl.a. leder till att synapsens form och funktion förändras.

2. Paul Greengard - Wikipedia En Español Translate this page Paul Greengard. De Wikipedia, la enciclopedia libre. Paul Greengard nacióen Nueva York en 1925. Se doctoró en Medicina y Filosofía http://es.wikipedia.org/wiki/Paul_Greengard

Paul Greengard De Wikipedia, la enciclopedia libre. Paul Greengard nació en Nueva York en . Se doctoró en Medicina y Filosofía en la Universidad John Hopkins , en Baltimore . Realizó estudios de postdoctorado en Londres Cambridge , en el Instituto Nacional de Investigaciones Médicas de Inglaterra . Fue director del Departamento de Bioquímica de Geigy y posteriormente catedrático de Farmacología y Psiquiatría en Nueva York y en New Haven . Desde desarolla su labor como director del Laboratorio de Neurociencia Molecular y Celular de la Universidad de Rockefeller en Nueva York. Greengard continuó la linea de investigación abierta por Arvid Carlsson , en el estudio de la dopamina serotonina y noradrenalina en la sinapsis neuronal Recibió el Premio Nobel de Fisiología o Medicina el año , compartido con Arvid Carlsson y Erik Kandel Views Artículo Discusión Editar Historial Herramientas personales Registrarse/Entrar Navegación Portada Portal de la comunidad Actualidad Cambios recientes ... Donativos Buscar Herramientas Lo que enlaza aquí Cambios en enlazadas Páginas especiales Esta página fue modificada por última vez el 20:24 27 feb, 2004. El contenido está disponible bajo los términos de GNU Free Documentation License Acerca de Wikipedia Aviso legal

3. Paul Greengard Translate this page Paul greengard paul Greengard nació en Nueva York en 1925. Se doctoró enMedicina y Filosofía en la Universidad John Hopkins, en Baltimore. http://www.guajara.com/wiki/es/wikipedia/p/pa/paul_greengard.html

Paul Greengard Paul Greengard nació en Nueva York en . Se doctoró en Medicina y Filosofía en la Universidad John Hopkins, en Baltimore. Realizó estudios de postdoctorado en Londres Cambridge , en el Instituto Nacional de Investigaciones Médicas de Inglaterra . Fue director del Departamento de Bioquímica de Geigy y posteriormente catedrático de Farmacología y Psiquiatría en Nueva York y en New Haven. Desde desarolla su labor como director del Laboratorio de Neurociencia Molecular y Celular de la Universidad de Rockefeller en Nueva York. Greengard continuó la linea de investigación abierta por Arvid Carlsson , en el estudio de la dopamina serotonina y noradrenalina en la sinapsis neuronal. Recibió el Premio Nobel de Fisiología o Medicina el año , compartido con Arvid Carlsson y Erik Kandel Tagoror.com CineBSO Radioaficionados.net ... Deranet El contenido de Wikipedia se publica bajo la Datos de Contacto

4. Paul Greengard Textbooks Textbooks & Books Price Comparison - Direct Textbook Search by ISBN, Title, Author, Keyword, or Advanced. Paul Greengard Textbooks.Next Textbooks by Paul Greengard. Next Textbooks by Paul Greengard. Love Us? http://www.directtextbook.com/author/paul-greengard

Search by ISBN, Title, Author, Keyword, or Advanced Paul Greengard Textbooks Next Textbooks by Paul Greengard Ion Channel Regulation Hardcover - Show all editions David Armstrong Sandra Rossie Paul Greengard ... Shirish Shenolikar , 15 April, 1999 Academic Press List Price: $116.95 ISBN: 0120361337 Current Methodology (Advances in Cyclic Nucleotide and Protein Phosphorylation Research: Vol 10) Hardcover - Show all editions Gary Brooker Paul Greengard G. Alan Robinson , June, 1979 Raven Press List Price: $70.50 ISBN: 0890042659 Fifth International Conference on Cyclic Nucleotides and Protein Phosphorylation, Milan Italy (Advances in Cyclic Nucleotide and Protein Phosphorylat) Hardcover - Show all editions Paul Greengard G. Alan Robison Rodolfo Paoletti ... Simonetta Nicosia , December, 1984 Raven Press List Price: $113.00 ISBN: 0890043493 Advances in Cyclic Nucleotide Research Hardcover - Show all editions Paul Greengard G. Alan Robinson , June, 1979 Raven Press List Price: $98.00 ISBN: 0890043639 Fourth International Conference on Cyclic Nucleotides, Brussells, Belgium (Advances in Cyclic Nucleotide and Protein Pshophorylation Research: Vol 1) Hardcover - Show all editions Jacques E. Dumont

5. Paul Greengard - Autobiography paul greengard – Autobiography. My paternal great, great grandfatheremigrated from Koenigsberg, now Gdansk, to St. Louis during http://www.nobel.se/medicine/laureates/2000/greengard-autobio.html

My paternal great, great grandfather emigrated from Koenigsberg, now Gdansk, to St. Louis during the 1850s, a time of large-scale movement of Germans, including German Jews, to the Mid-Western United States. My paternal grandfather moved to Binghamton, New York, where my father was born. My father had success in vaudeville as a singer/dancer/comedian. He eventually became a businessman working first in retail and then in wholesale in the cosmetics field. I attended public schools in Brooklyn and Queens. During World War II, I spent three years in the Navy as an electronics technician. After appropriate training, I was assigned to a team at the Massachusetts Institute of Technology that was involved in developing an early-warning system to intercept Japanese kamikaze planes before they could reach the ships of the U.S. fleet. After the war, I attended Hamilton College , a small liberal arts college located in Clinton, New York, where I majored in mathematics and physics, and from which I graduated in 1948. I had been interested in going to graduate school in theoretical physics, but decided not to do so because at that time the only fellowship support for such graduate studies came from the Atomic Energy Commission. This was only three years after dropping the atomic bombs on Japan, and I didn't want to contribute to research the fruits of which might contribute to creating more powerful weapons of mass destruction. In thinking about various options, I settled on the then nascent field of biophysics. At that time there were two groups of academic biophysicists. One, at the University of California, was engaged in biological and medical applications of radioisotopes. The other, at the

6. Paul Greengard Lab Laboratory of Molecular and Cellular Neuroscience. paul greengard. Vincent Astor Professor. The goal of our laboratory is to understand more fully the molecular basis of communication between neurons http://www.rockefeller.edu/labheads/greengard/greengard-lab.html

Laboratory of Molecular and Cellular Neuroscience Paul Greengard Vincent Astor Professor The goal of our laboratory is to understand more fully the molecular basis of communication between neurons in the mammalian brain. Toward this end, we have developed a general model of signal transduction in the nervous system. The major molecular mechanism underlying signal transduction is protein phosphorylation. Synaptic Vesicle-associated Phosphoproteins. The major synaptic vesicle-associated phosphoproteins that we have identified and characterized are synapsin I, synapsin II, and synaptophysin. As an example of the functioning of this class of phosphoproteins, we have obtained evidence that dephosphorylated synapsin I functions to tether synaptic vesicles in a "reserve" pool. When synapsin I is phosphorylated, this tethering function is abolished, and the synaptic vesicles are then free to enter a "readily releasable" pool of synaptic vesicles. Additionally, we have obtained evidence that the synapsins are involved in the formation of new synapses. Neostriatum-enriched Phosphoproteins.

7. Online NewsHour: A Nobel Winner- October 11, 2000 paul greengard, one of this years winners of the Nobel Prize in medicine, joins Dr of them is with us now. paul greengard is a neuroscientist who heads the laboratory http://www.pbs.org/newshour/bb/science/july-dec00/nobel-med_10-9.html

A NOBEL WINNER October 11 , 2000 Paul Greengard, one of this year’s winners of the Nobel Prize in medicine, joins Dr. Steve Hyman, director of the National Institute of Mental Health, to talk about his research and winning the Nobel Prize. RAY SUAREZ: The award this year went for discoveries about how messages move around the nervous system and help us understand the functioning of the brain. Three scientists will share the nearly $1 million prize. One of them is with us now. Paul Greengard is a neuroscientist who heads the laboratory of molecular and cellular neuroscience at the Rockefeller University in New York. Also joining us is Dr. Steve Hyman, director of the National Institute of Mental Health. First, Professor Greengard, congratulations. PAUL GREENGARD: Thank you very much. RAY SUAREZ: How did you hear about the award? PAUL GREENGARD: About ten minutes past five this morning, the secretary of the Nobel Committee called to inform me I had been one of the recipients of this year's Nobel Prize in medicine. It was about 20 minutes... apparently in Sweden they announce at 11:30 in the morning, which is 5:30 Eastern Standard time. So they called to let the recipients know in advance of the deluge of telephone calls that come after the announcement of the prize.

8. NARSAD: Research Center: Project Summary For Paul Greengard, Ph.D. paul greengard, Ph.D. ( Distinguished Investigator 2002) of Rockefeller University, proposes to initiate a strategy to http://www.narsad.org/research/summaries/greengardpaul-2002.html

Paul Greengard, Ph.D. (Distinguished Investigator 2002) of Rockefeller University, Program Area: SCHIZOPHRENIA/PSYCHOTIC DISORDERS Search Again NARSAD // 60 Cutter Mill Road, Suite 404, Great Neck, New York 11021 USA // phone 1 (800) 829-8289 // fax 516 487-6930 // e-mail info@narsad.org legal notice sitemap

9. The Scientist :: 2000 Nobel Goes To Arvid Carlsson, Paul Greengard And Eric Kand 2000 Nobel goes to Arvid Carlsson, paul greengard and Eric Kandel. Slow synaptic transmission grabs the Nobel for Physiology or Medicine. Robert Walgate. LONDON. So, it wasn't the human genome; nor http://www.biomedcentral.com/news/20001009/02

Previous Next 2000 Nobel goes to Arvid Carlsson, Paul Greengard and Eric Kandel Robert Walgate LONDON. So, it wasn't the human genome; nor the nematode. Today, nerves seem to have got to the Nobel Assembly at the Karolinska Institute, Stockholm, which this morning announced the award of the Nobel Prize in Physiology or Medicine for 2000 jointly to Arvid Carlsson, Paul Greengard and Eric Kandel. Aplysia Aplysia's gills to study learning. He demonstrated that short term and long term memory in the sea slug are located at the synapse. In the 1990s he extended these studies to mice, and showed that the same type of changes in synaptic function also take place in mammals. This Nobel is Kandel's 29th scientific prize or medal, including the Lasker Award (with VB Mountcastle) in 1983. Arvid Carlsson, 77, of the Department of Pharmacology, University of Gothenburg, was rewarded "for his discovery that dopamine is a transmitter in the brain and that it has great importance for our ability to control movements." The Karolinska emphasises Carlsson's contributions to the development of L-dopa as a treatment for Parkinson's disease, to the understanding of the action of drugs for schizophrenia, and the development of selective serotonin uptake blockers as antidepressants. The Nobel is Carlsson's 26th scientific award. Links for this article Press release: The Nobel Prize in Physiology or Medicine for 2000 http://www.nobel.se/announcement/2000/medicine.html

10. The Rockefeller University - Research And Faculty Goulianos, Konstantin. greengard, paul. Hatten, Mary E. Heintz, Nathaniel Printerfriendly format. greengard, paul. Vincent Astor Professor. E-mail greengd@rockefeller.edu http://www.rockefeller.edu/labheads/greengard/greengard.html

Select area of study Immunology, Virology and Microbiology Medical Sciences and Human Genetics Molecular, Cell and Developmental Biology Neuroscience Physics and Mathematical Biology Biochemistry, Structural Biology and Chemistry Not Specified Select lab head name Allis, C. David Blobel, Günter Breslow, Jan L. Brivanlou, Ali H. Chait, Brian T. Chua, Nam-Hai Cohen, Joel E. Coller, Barry Cross, George A.M. Cross, Frederick R. Darnell, James E. Darnell, Robert Darst, Seth de Lange, Titia Dhodapkar, Madhav Feigenbaum, Mitchell J. Fischetti, Vincent A. Friedman, Jeffrey M. Fuchs, Elaine Funabiki, Hironori Gaasterland, Terry Gadsby, David C. Gaul, Ulrike Gilbert, Charles D. Gotschlich, Emil C. Goulianos, Konstantin Greengard, Paul Hatten, Mary E. Heintz, Nathaniel Ho, David D. Hudspeth, A. James Kapoor, Tarun Karayiorgou, Maria Khuri, Nicola N. Knight, Bruce W. Konarska, Magda Kreek, Mary Jeanne Krueger, James G. Leibler, Stanislas Libchaber, Albert MacKinnon, Roderick Magnasco, Marcelo O. McEwen, Bruce S. McKinney, John D. Mombaerts, Peter Muir, Tom Münz, Christian

11. Medicine 2000 Medicine 2000. for their discoveries concerning signal transductionin the nervous system . Arvid Carlsson, paul greengard, Eric R. Kandel. http://www.nobel.se/medicine/laureates/2000/

The Nobel Prize in Physiology or Medicine 2000 "for their discoveries concerning signal transduction in the nervous system" Arvid Carlsson Paul Greengard Eric R. Kandel 1/3 of the prize 1/3 of the prize 1/3 of the prize Sweden USA USA Göteborg University Gothenburg, Sweden Rockefeller University New York, NY, USA Columbia University New York, NY, USA b. 1923 b. 1925 b. 1929 (in Vienna, Austria) The Nobel Prize in Physiology or Medicine 2000 Press Release Presentation Speech Educational ... Other Resources The 2000 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified October 12, 2000 The Official Web Site of The Nobel Foundation

12. Paul Greengard Winner Of The 2000 Nobel Prize In Physiology Or Medicine paul greengard, the 2000 Nobel Prize Laureate in Physiology or Medicine, at the Nobel Prize Internet Archive. Prize corecipient Eric Kandel. paul greengard Lab at the Rockefeller University http://www.almaz.com/nobel/medicine/2000b.html

P AUL G REENGARD 2000 Nobel Laureate in Physiology or Medicine for their discoveries concerning signal transduction in the nervous system Background Born: December 11, 1925 Place of birth: New York, NY, USA Residence: New York Affiliation: Laboratory of Molecular and Cellular Neuroscience, Rockefeller University Address: Laboratory of Molecular and Cellular Neuroscience The Rockefeller University 1230 York Avenue, New York, NY 10021, USA E-mail: greengd@rockvax.rockefeller.edu Book Store Principles of Neural Science, 4th Edition Books on Signal Transduction Books on the nervous system Books on dopamine ... Books by Eric Kandel Featured Internet Links Prize co-recipient: Arvid Carlsson Prize co-recipient: Eric Kandel Paul Greengard Lab at the Rockefeller University Publications ... Curriculum vitae Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors Professor Paul Greengard Donates $100,000 for Pearl Meister Distinguished Lecture Paul Greengard - Prize Award Photo (submitted by Daike) Yahoo! Encyclop¨¦die - Paul Greengard

13. The Rockefeller University - Research And Faculty Printerfriendly format. greengard, paul Vincent Astor Professor E-mailgreengd@rockefeller.edu, Lab Web Page Lab Members Publications http://www.rockefeller.edu/research/abstract.php?id=53

14. Greengard, Paul greengard, paul (1925). My paternal great, great grandfather emigratedfrom Koenigsberg, now Gdansk, to St. Louis during the 1850s http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/G/Greengard/Gree

Greengard, Paul My paternal great, great grandfather emigrated from Koenigsberg, now Gdansk, to St. Louis during the 1850s, a time of large-scale movement of Germans, including German Jews, to the Mid-Western United States. My paternal grandfather moved to Binghamton, New York, where my father was born. My father had success in vaudeville as a singer/dancer/comedian. He eventually became a businessman working first in retail and then in wholesale in the cosmetics field. I was born on December 11, 1925 in New York City under tragic circumstances - my mother, née Pearl Meister, died giving birth to me. My father remarried when I was 13 months old. In contrast to my mother, who had been Jewish, my stepmother, who raised me, was Episcopalian. From that time on I was brought up in the Christian tradition, celebrating Easter, Christmas, etc. I was prevented access to my biological mother's family with whom I became familiar only very recently. I have been delighted to learn that many members of that family are highly creative individuals working in various fields of science, government, etc. I attended public schools in Brooklyn and Queens. During World War II, I spent three years in the Navy as an electronics technician. After appropriate training, I was assigned to a team at the Massachusetts Institute of Technology that was involved in developing an early-warning system to intercept Japanese kamikaze planes before they could reach the ships of the U.S. fleet.

15. Themes Geography History History Prize Winners Nobel 1999, Blobel, Günter. 2000, Carlsson, Arvid greengard, paul - Kandel,Eric R. 2001, Hartwell, Leland H. - Hunt, R. Timothy - Nurse, paul M. -. http://www.cartage.org.lb/en/themes/GeogHist/histories/prizewinners/nobelprize/m

Themes History Prize Winners Nobel Prize Year Winners Behring, Emil Adolf von Ross, Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich ... Bárány, Robert The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section The prize money was allocated to the Special Fund of this prize section Bordet, Jules Krogh, Schack August Steenberg The prize money was allocated to the Special Fund of this prize section Hill, Archibald Vivian Meyerhof, Otto Fritz Banting, Frederick Grant Macleod, John James Richard ... Einthoven, Willem The prize money was allocated to the Special Fund of this prize section Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan ... Domagk, Gerhard The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section The prize money was 1/3 allocated to the Main Fund and 2/3 to the Special Fund of this prize section Dam, Henrik Carl Peter

16. Advances In Cyclic Nucleotide And Protein Phosphorylation Research; Author: Gree Advances in Cyclic Nucleotide and Protein Phosphorylation Research Author greengard, paul (Et Al) http://www.netstoreusa.com/aubooks/088/0881672424.shtml

Advances in Cyclic Nucleotide and Protein Phosphorylation Research English Books German Books Spanish Books Sheet Music ... NEW RELEASES Advances in Cyclic Nucleotide and Protein Phosphorylation Research Author: Greengard, Paul (Et Al) Hardback; Book Non-Subscriber ISBN: 0881672424 This item non-returnable. Order may not be canceled. PRODUCT CODE: 0881672424 USA/Canada: US$ 183.80 Australia/NZ: A$ 127.20 Other Countries: US$ 199.70 convert to your currency Delivery costs included if your total order exceeds US$50. We do not charge your credit card until we ship your order. Government and corporate Purchase Orders accepted without prior account application. PLACE AN ORDER To prepare to buy this item click "add to cart" above. You can change or abandon your shopping cart at any time before checkout. CHECK ORDER STATUS Check on order progress and dispatch. CHANGE OR CANCEL YOUR ORDER Please E-mail us within one hour The NetStoreUSA website is operated by Open Communications, Inc an Arizona corporation, which has successfully served the Internet community since 1994.

17. MSN Encarta - Greengard, Paul Already a subscriber? Sign in above. greengard, paul. Find more about greengard,paul from, Other Features from Encarta. Search Encarta for greengard, paul. http://encarta.msn.com/encyclopedia_681500374/Greengard_Paul.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Greengard, Paul Greengard, Paul (1925- ), American neuroscientist and Nobel laureate who studied the biochemical steps involved in the way billions of nerve cells, or... Related Items Nobel Prize cowinners 2 items Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Greengard, Paul from Other Features from Encarta Search Encarta for Greengard, Paul Try MSN Internet Software for FREE! MSN Home ... Feedback

18. MSN Encarta - Related Items - Nobel Prizes Goldstein, Joseph Leonard. Golgi, Camillo. Granit, Ragnar A. greengard, paul.Guillemin, Roger Charles Louis. Gullstrand, Allvar. Hartline, Haldan Keffer. http://encarta.msn.com/related_761567175_12/physiology_or_medicine.html

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19. Paul Greengard --  Britannica Concise Encyclopedia Online Article greengard, paul Britannica Concise. MLA style paul greengard. BritannicaConcise Encyclopedia. 2004. Encyclopædia Britannica Premium Service. http://www.britannica.com/ebc/article?eu=409681&query=neural process&ct=

20. Paul Greengard Translate this page Nobelpreis fuer Medizin 2000 (Nobel Prize Medicine 2000) PaulGreengard, amerikan. Pharmakologe, geb. 11. Dez. 1925. http://www.zuta.de/npmed/greengard.htm

Nobelpreis fuer Medizin 2000 (Nobel Prize Medicine 2000) Paul Greengard, amerikan. Pharmakologe, geb. 11. Dez. 1925

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