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  1. Robert F. Furchgott

1. Robert F. Furchgott - Wikipedia, The Free Encyclopedia
Robert F. Furchgott. (Redirected from Robert F Furchgott). Robert F. Furchgott(born June 4, 1916). Furchgott was born in Charleston, South Carolina.
http://en.wikipedia.org/wiki/Robert_F_Furchgott
Robert F. Furchgott
From Wikipedia, the free encyclopedia.
(Redirected from Robert F Furchgott Robert F. Furchgott (born June 4 Furchgott was born in Charleston, South Carolina . He studied chemistry and biochemistry . He graduated in chemistry in 1937 at the University of North Carolina , and became doctor of biochemistry at the Northwestern University in 1940. From 1956 to 1988, he was professor of pharmacology at the State University of New York In 1978, Furchgott discovered a substance in endothelial cells that relaxes blood vessels, calling it endothelium-derived relaxing factor (EDRF). By 1986, he had worked out EDRF's nature and mechanism of action, and determined that EDRF was in fact nitric oxide (NO), an important compound in many aspects of cardiovascular physiology. For his groundbreaking discoveries, he was awarded in 1991 the http://www.gairdner.org/ International Awards for achievement in medical research, the http://www.laskerfoundation.org/awards/library/1996basic.shtml in 1996, and then in 1998 the Nobel Prize in Medicine Furchgott has three children. Currently (2004), he lives in

2. Robert F. Furchgott - Wikipedia, The Free Encyclopedia
Robert F. Furchgott. From Wikipedia, the free encyclopedia. Robert F. Furchgott(born June 4, 1916). Furchgott was born in Charleston, South Carolina.
http://en.wikipedia.org/wiki/Robert_F._Furchgott
Robert F. Furchgott
From Wikipedia, the free encyclopedia.
Robert F. Furchgott (born June 4 Furchgott was born in Charleston, South Carolina . He studied chemistry and biochemistry . He graduated in chemistry in 1937 at the University of North Carolina , and became doctor of biochemistry at the Northwestern University in 1940. From 1956 to 1988, he was professor of pharmacology at the State University of New York In 1978, Furchgott discovered a substance in endothelial cells that relaxes blood vessels, calling it endothelium-derived relaxing factor (EDRF). By 1986, he had worked out EDRF's nature and mechanism of action, and determined that EDRF was in fact nitric oxide (NO), an important compound in many aspects of cardiovascular physiology. For his groundbreaking discoveries, he was awarded in 1991 the http://www.gairdner.org/ International Awards for achievement in medical research, the http://www.laskerfoundation.org/awards/library/1996basic.shtml in 1996, and then in 1998 the Nobel Prize in Medicine Furchgott has three children. Currently (2004), he lives in Brooklyn edit
See also
edit
External links
  • Professor Furchgott's autobiography http://www.nobel.se/medicine/laureates/1998/furchgott-autobio.html

3. Robert F. Furchgott - Encyclopedia Article About Robert F. Furchgott. Free Acces
encyclopedia article about Robert F. Furchgott. Robert F. Furchgott in Free onlineEnglish dictionary, thesaurus and encyclopedia. Robert F. Furchgott.
http://encyclopedia.thefreedictionary.com/Robert F. Furchgott
Dictionaries: General Computing Medical Legal Encyclopedia
Robert F. Furchgott
Word: Word Starts with Ends with Definition Robert F. Furchgott (born June 4 June 4 is the 155th day of the year in the Gregorian calendar (156th in leap years), with 210 days remaining.
Events
  • 780 BC - The first historic solar eclipse is recorded in China
  • 1039 - Henry II becomes King of Germany
  • 1070 - Roquefort cheese is created in a cave near Roquefort, France
  • 1760 - New England planters arrive to take land in Nova Scotia Canada taken from the Acadians

Click the link for more information. Centuries: 19th century - 20th century - 21st century Decades: 1860s 1870s 1880s 1890s 1900s - Years: 1911 1912 1913 1914 1915 - This is a leap year starting on Saturday (link will take you to calendar)
Events
  • January 8 - Allied forces withdraw from Gallipoli
  • January 17 - The Professional Golfers Association (PGA) is formed

Click the link for more information. Furchgott was born in Charleston, South Carolina Charleston is an American city located predominately in Charleston County, South Carolina. The city was founded as Charles Town in 1670, and moved to its present location in 1690, when it had a population of 1200 and was the fifth largest city in North America. It adopted its present name in 1783.

4. Robert F Furchgott - Encyclopedia Article About Robert F Furchgott. Free Access,
encyclopedia article about Robert F Furchgott. Robert F Furchgott in Free onlineEnglish dictionary, thesaurus and encyclopedia. Robert F Furchgott.
http://encyclopedia.thefreedictionary.com/Robert F Furchgott
Dictionaries: General Computing Medical Legal Encyclopedia
Robert F Furchgott
Word: Word Starts with Ends with Definition Robert F. Furchgott (born June 4 June 4 is the 155th day of the year in the Gregorian calendar (156th in leap years), with 210 days remaining.
Events
  • 780 BC - The first historic solar eclipse is recorded in China
  • 1039 - Henry II becomes King of Germany
  • 1070 - Roquefort cheese is created in a cave near Roquefort, France
  • 1760 - New England planters arrive to take land in Nova Scotia Canada taken from the Acadians

Click the link for more information. Centuries: 19th century - 20th century - 21st century Decades: 1860s 1870s 1880s 1890s 1900s - Years: 1911 1912 1913 1914 1915 - This is a leap year starting on Saturday (link will take you to calendar)
Events
  • January 8 - Allied forces withdraw from Gallipoli
  • January 17 - The Professional Golfers Association (PGA) is formed

Click the link for more information. Furchgott was born in Charleston, South Carolina Charleston is an American city located predominately in Charleston County, South Carolina. The city was founded as Charles Town in 1670, and moved to its present location in 1690, when it had a population of 1200 and was the fifth largest city in North America. It adopted its present name in 1783.

5. Robert F Furchgott - Wikipedia
Robert F Furchgott. Från Wikipedia, den fria encyklopedin. Robert F Furchgott,född 1916. Amerikansk nobelpristagare i fysiologi eller medicin år 1998.
http://sv.wikipedia.org/wiki/Robert_F_Furchgott
Robert F Furchgott
Från Wikipedia, den fria encyklopedin.
Robert F Furchgott , född Amerikansk nobelpristagare i fysiologi eller medicin år . Han tilldelades priset för sina " upptäckter rörande kväveoxid som en signalmolekyl i hjärt-kärlsystemet ". Han delade priset med sina landsmän Louis J Ignarro och Ferid Murad . Furchgott tog doktorsexamen i biokemi vid Northwestern University . Han blev professor i farmakologi vid State University of New York . Sedan har han titeln Distinguished Professor Kväveoxid (NO) är en gas som överför signaler i kroppen. Kväveoxid som produceras i en cell , tränger igenom cellmembranen till andra celler och reglerar funktionen i dessa. Att en gas kan ha denna funktion är en helt ny upptäckt. Robert F Furchgott studerade effekten av olika medicinerblodkärlen och fick flera gånger motsägande resultat. En och samma medicin orsakade ibland sammandragning och vid andra tillfällen utvidgning av kärlen. Han funderade på om dessa variationer kunde bero på om ytcellerna i kärlens väggar var skadade eller inte. visade han att utvidgningen av kärlen endast skedde om cellerna var oskadade och att det skedde genom att cellerna producerade en speciell signalmolekyl. Han kallade denna molekyl ERDF (

6. Robert F Furchgott - Wikipedia
Robert F Furchgott. (Omdirigerad från Robert F. Furchgott). Robert F Furchgott,född 1916. Amerikansk nobelpristagare i fysiologi eller medicin år 1998.
http://sv.wikipedia.org/wiki/Robert_F._Furchgott
Robert F Furchgott
Från Wikipedia, den fria encyklopedin.
(Omdirigerad från Robert F. Furchgott Robert F Furchgott , född Amerikansk nobelpristagare i fysiologi eller medicin år . Han tilldelades priset för sina " upptäckter rörande kväveoxid som en signalmolekyl i hjärt-kärlsystemet ". Han delade priset med sina landsmän Louis J Ignarro och Ferid Murad . Furchgott tog doktorsexamen i biokemi vid Northwestern University . Han blev professor i farmakologi vid State University of New York . Sedan har han titeln Distinguished Professor Kväveoxid (NO) är en gas som överför signaler i kroppen. Kväveoxid som produceras i en cell , tränger igenom cellmembranen till andra celler och reglerar funktionen i dessa. Att en gas kan ha denna funktion är en helt ny upptäckt. Robert F Furchgott studerade effekten av olika medicinerblodkärlen och fick flera gånger motsägande resultat. En och samma medicin orsakade ibland sammandragning och vid andra tillfällen utvidgning av kärlen. Han funderade på om dessa variationer kunde bero på om ytcellerna i kärlens väggar var skadade eller inte. visade han att utvidgningen av kärlen endast skedde om cellerna var oskadade och att det skedde genom att cellerna producerade en speciell signalmolekyl. Han kallade denna molekyl ERDF (

7. Robert F. Furchgott
Robert F. Furchgott. Robert F. Furchgott (born June 4, 1916). Furchgott wasborn in Charleston, South Carolina. He studied chemistry and biochemistry.
http://www.sciencedaily.com/encyclopedia/robert_f__furchgott
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Robert F. Furchgott
Robert F. Furchgott (born June 4 ). Furchgott was born in Charleston, South Carolina . He studied chemistry and biochemistry . He graduated in chemistry in 1937 at the University of North Carolina , and became doctor of biochemistry at the Northwestern University in 1940. From 1956 to 1988, he was professor of pharmacology at the State University of New York . In 1978, Furchgott discovered a substance that relaxes muscle cells, calling it endothelium derived relaxing factor (EDRF), which later turned out to be nitrogen monoxide (NO), and is today known to be a

8. Robert Furchgott
light. Selected Publications. furchgott, RF, and Zawadzki, JV (1980).The acetylcholine. Nature 288, 373376. furchgott, RF (1983). Role
http://www.hscbklyn.edu/pharmacology/furch.htm
The Nature of the Endothelium-Derived Relaxing Factor Our research includes studies on the mechanisms by which various vasodilators, both endothelium-dependent and independent, and near ultraviolet radiation produce relaxation of vascular smooth muscle. Also, we are investigating whether the endothelium-derived relaxing factor (EDRF) is simply nitric oxide or a mixture of substances. In 1980, we reported that endothelial cells have an obligatory role in the relaxation of arteries by acetylcholine (ACh) and related muscarinic agonists, and that the relaxation results from the stimulation by the muscarinic agonist of the release from the endothelial calls of a very labile diffusible factor which acts on the adjacent smooth muscle cells to cause their relaxation. This factor was called the endothelium-derived relaxing factor (EDRF). Within a short time, a number of other endothelium-dependent vasodilators were found. EDRF released from endothelial cells was shown to activate soluble guanylyl cyclase in the smooth muscle cells, giving rise to an increase in cyclic guanosine monophosphate (cGMP), which appeared to have a causal role in producing the relaxation. Although some very potent scavengers of EDRF, such as hemoglobin (Hb) and the superoxide anion (O ) were discovered, the chemical nature of EDRF eluded identification until 1986, when it was proposed independently by us and by one other investigator at an international conference that EDRF is nitric oxide (NO). Within two years after that, other laboratories had demonstrated that the NO synthesized in endothelial cells is a product of the action of a calcium/calmodulin dependent oxygenase, nitric oxide synthase (NOS), which oxidizes a guanidinium nitrogen of L-arginine to yield NO and citrulline (see Fig. 1).

9. Robert F. Furchgott - Autobiography
robert F. furchgott – Autobiography. Early education I was born in the lovelycoastal city of Charleston, SC in 1916 and lived there until I was thirteen.
http://www.nobel.se/medicine/laureates/1998/furchgott-autobio.html
Early education
Within the first couple of years of high school, I knew that I would like to be a scientist. My parents were encouraging: they gave me chemistry sets and a small microscope as presents. I liked to read popular books about scientists, although there were not many available at that time. My father subscribed to the Sunday New York Times, in which there was often a column on science that I found very exciting.
During the four years that I was in high school, my older brother Arthur was at the University of North Carolina at Chapel Hill. I wanted to attend college there also, but that was not possible when I finished high school in 1933 because tuition for me, as an out-of-state resident, was more than my father could afford at that time. So I spent my freshman year at the University of South Carolina , where my tuition was much less. However, by the summer of 1934, my father moved his business from Orangeburg to Goldsboro, N.C., where he felt that the local economy was better. So now, as a resident of North Carolina, I was able to register at the University at Chapel Hill as a sophomore majoring in chemistry.
Northwestern University
Medical School in Chicago. I was to be a graduate student of Dr Henry Bull, who had recently come to Northwestern, and whose research interests were physical chemical aspects of biochemistry.

10. Medicine 1998
for their discoveries concerning nitric oxide as a signalling molecule in thecardiovascular system . robert F. furchgott, Louis J. Ignarro, Ferid Murad.
http://www.nobel.se/medicine/laureates/1998/
The Nobel Prize in Physiology or Medicine 1998
"for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system" Robert F. Furchgott Louis J. Ignarro Ferid Murad 1/3 of the prize 1/3 of the prize 1/3 of the prize USA USA USA SUNY Health Science Center
Brooklyn, NY, USA University of California School of Medicine
Los Angeles, CA, USA University of Texas Medical School at Houston
Houston, TX, USA b. 1916 b. 1941 b. 1936 The Nobel Prize in Physiology or Medicine 1998
Press Release

Presentation Speech

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...
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The 1998 Prize in:
Physics

Chemistry

Physiology or Medicine
Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified August 27, 2003 The Official Web Site of The Nobel Foundation

11. Dr. Robert F. Furchgott, Nobel Laureate
Dr. robert F. furchgott. SUNY Health Science Center at Brooklyn. Dr. furchgott was awarded the 1998 Nobel Prize in Medicine for his discoveries concerning "nitric oxide as a
http://www.rfsuny.org/50_anniversary/nobel_laureates/Furchgott.htm
Dr. Robert F. Furchgott SUNY Health Science Center at Brooklyn Dr. Furchgott was awarded the 1998 Nobel Prize in Medicine for his discoveries concerning "nitric oxide as a signaling molecule in the cardiovascular system." In 1980, Dr. Furchgott published his discovery of endothelium-derived relaxing factor (EDRF), a mysterious chemical in the inner linings of the arteries that controls the artery’s widening and narrowing. Six years later, he identified EDRF as nitric oxide. Dr. Furchgott’s findings opened up a new area of research, which is contributing much to our understanding of cardiovascular physiology and is helping doctors save lives.

12. Robert F. Furchgott 1916 - Loius J. Ignarro 1941 - Ferid Murad 1936
Scientists build on each other's work. furchgott, while studying the effects of drugs on blood vessels, discovered that blood vessels dilate when their surface cells ( consistent with the hypothesis." robert F. furchgott, Les Prix Nobel, 1998. robert F. furchgott was born in
http://history.nih.gov/exhibits/rodbell/1_Furchgott_Ignarro_Murad.htm
S cientists build on each other's work. Furchgott, while studying the effects of drugs on blood vessels, discovered that blood vessels dilate when their surface cells (the endothelium) signal the muscle cells to relax, using a molecule he called "endothelium-derived relaxing factor" or EDRF. Murad noticed that nitroglycerin (which dilates blood vessels) releases the gas nitric oxide (NO) which relaxes the smooth muscles. Ignarro also analyzed EDRF and discovered at the same time as Furchgott that EDRF was truly NO. This was the first evidence that a gas may act as a signal molecule. NO has recently been found to be important in fighting infections, regulating blood pressure, and activating brain functions. For more information about their work, see www.nobel.se/medicine/laureates/1998/press.html
"I think that my greatest pleasure has come from each first demonstration in my laboratory that experiments designed to test a new hypothesis developed to explain some earlier, often puzzling or paradoxical finding, have given results consistent with the hypothesis." Robert F. Furchgott, Les Prix Nobel, 1998
Robert F. Furchgott was born in Charleston, South Carolina in 1916, with an innate interest in biology and science. He attended both the Universities of South and North Carolina and did his Ph.D. work at Northwestern University in Chicago. He worked at Cornell University Medical College on phosphates, Washington University in St. Louis on smooth muscles, and at Suny Medical Center in Brooklyn on the relaxation of blood vessels. For more about Furchgott, see

13. Biography-center - Letter F
www.kfki.hu/~arthp/bio/f/fabritiu/ biograph.html .edu/art/collections/bio/a17531.html. furchgott, robert F. www.nobel.se/medicine/laureates/1998/ furchgott-autobio.html
http://www.biography-center.com/f.html
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14. Robert F. Furchgott Winner Of The 1998 Nobel Prize In Medicine
robert F. furchgott, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. robert F. furchgott. 1998 Nobel Laureate in Medicine Genbrain Biosystem Network .
http://www.almaz.com/nobel/medicine/1998a.html
R OBERT F F URCHGOTT
1998 Nobel Laureate in Medicine
    for his discovery concerning nitric oxide as a signalling molecule in the cardiovascular system.
Background
  • Born: June 4, 1916
  • Place of birth: Charleston, South Carolina, U.S.A.
  • Residence: Brooklyn, NY, U.S.A.
  • Affiliation:Department of Pharmacology, Box 29, SUNY Health Science Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Book Store Featured Internet Links Links added by Nobel Internet Archive visitors

15. Candidates
SUNY Downstate Congratulates Dr. robert F. furchgott uponhis having been awarded the Nobel Prize in Medicine.
http://www.downstate.edu/Nobel Prize/dr._furchgott.htm
SUNY Downstate
Congratulates Dr. Robert F. Furchgott
upon his having been awarded the
Nobel Prize in Medicine.
SUNY Downstate Celebrates this

historic event!

In 1980, Dr. Furchgott published his discovery of endothelium-derived relaxing factor (EDRF), a mysterious chemical in the inner linings of the arteries that controls the artery's widening and narrowing.
By 1986, he had worked out EDRF's nature and mechanism and, from his 6th floor lab at the SUNY Health Science Center at Brooklyn, announced that EDRF was in fact the tiny molecule nitric oxide (NO).Between those years, laboratories around the globe were detailing EDRF's importance in the body's physiology, from regulating blood pressure to preventing blood clots.
Dr. Furchgott's work in the laboratory is now helping doctors save lives. Further Reading
Diploma

A
utobiography Biography ... Congratulations letter from Governer George E. Pataki Web site design: Biomedical Communications Last updated: Thursday, May 6, 2004 l SUNY Downstate l Library l WebCT l News and Events l l Travel Directions l Site Map l Search l E-Mail l

16. Nobel Celebration
Chancellor John W. Ryan. Warm words from Dr. Eugene Feigelson. One Happy Family.Professor of Pharmacology Dr.Stanley Friedman. Dr. robert F.furchgott.
http://www.downstate.edu/nc/nobel_celebration.htm
SUNY Downstate acknowledges Dr. Robert Furchgott
the 1998 recipient of the Nobel Prize in Medicine
Standing Room Only Dr. Furchgott and President Feigelson Dr. Furchgott with SUNY's Chancellor John W. Ryan
Chancellor John W. Ryan Warm words from Dr. Eugene Feigelson
One Happy Family Professor of Pharmacology
Dr.Stanley Friedman Dr. Robert F.Furchgott
Chancellor John W. Ryan, Brooklyn Borough President Howard Golden,
Dr. Robert F.Furchgott and SUNY Downstate President Dr.Eugene Feigelson
The SUNY Downstate community comes out in mass to greet Dr. Furchgott. Return to main SUNY page Designed by the Department of Biomedical Communications

17. Robert F. Furchgott Winner Of The 1998 Nobel Prize In Medicine
robert F. furchgott, a Nobel Prize Laureate in Physiology and Medicine,at the Nobel Prize Internet Archive. robert F. furchgott.
http://almaz.com/nobel/medicine/1998a.html
R OBERT F F URCHGOTT
1998 Nobel Laureate in Medicine
    for his discovery concerning nitric oxide as a signalling molecule in the cardiovascular system.
Background
  • Born: June 4, 1916
  • Place of birth: Charleston, South Carolina, U.S.A.
  • Residence: Brooklyn, NY, U.S.A.
  • Affiliation:Department of Pharmacology, Box 29, SUNY Health Science Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Book Store Featured Internet Links Links added by Nobel Internet Archive visitors

18. Candidates
SUNY Downstate Celebrates this. historic event! In 1980, Dr. Congratulates Dr. robert F. furchgott. upon his having been awarded the In 1980, Dr. furchgott published his discovery of endotheliumderived relaxing factor (EDRF), a mysterious
http://www.hscbklyn.edu/Nobel Prize/dr._furchgott.htm
SUNY Downstate
Congratulates Dr. Robert F. Furchgott
upon his having been awarded the
Nobel Prize in Medicine.
SUNY Downstate Celebrates this

historic event!

In 1980, Dr. Furchgott published his discovery of endothelium-derived relaxing factor (EDRF), a mysterious chemical in the inner linings of the arteries that controls the artery's widening and narrowing.
By 1986, he had worked out EDRF's nature and mechanism and, from his 6th floor lab at the SUNY Health Science Center at Brooklyn, announced that EDRF was in fact the tiny molecule nitric oxide (NO).Between those years, laboratories around the globe were detailing EDRF's importance in the body's physiology, from regulating blood pressure to preventing blood clots.
Dr. Furchgott's work in the laboratory is now helping doctors save lives. Further Reading
Diploma

A
utobiography Biography ... Congratulations letter from Governer George E. Pataki Web site design: Biomedical Communications Last updated: Thursday, May 6, 2004 l SUNY Downstate l Library l WebCT l News and Events l l Travel Directions l Site Map l Search l E-Mail l

19. Index Of Nobel Laureates In Medicine
Florey, Lord Howard Walter, 1945. Forssmann, Werner, 1956. Frisch, Karl Von, 1973.furchgott, robert F. 1998. Gajdusek, D. Carleton, 1976. Gasser, Herbert Spencer,1944.
http://almaz.com/nobel/medicine/alpha.html
ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE
Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

20. Furchgott, Robert F.
furchgott, robert F. (1916). Early education I was born in the lovely coastalcity of Charleston, SC in 1916 and lived there until I was thirteen.
http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/F/Furchgott/Furc
Furchgott, Robert F. Early education
Within the first couple of years of high school, I knew that I would like to be a scientist. My parents were encouraging: they gave me chemistry sets and a small microscope as presents. I liked to read popular books about scientists, although there were not many available at that time. My father subscribed to the Sunday New York Times, in which there was often a column on science that I found very exciting. During the four years that I was in high school, my older brother Arthur was at the University of North Carolina at Chapel Hill. I wanted to attend college there also, but that was not possible when I finished high school in 1933 because tuition for me, as an out-of-state resident, was more than my father could afford at that time. So I spent my freshman year at the University of South Carolina, where my tuition was much less. However, by the summer of 1934, my father moved his business from Orangeburg to Goldsboro, N.C., where he felt that the local economy was better. So now, as a resident of North Carolina, I was able to register at the University at Chapel Hill as a sophomore majoring in chemistry. Northwestern and Cold Spring Harbor (1937-1940) Before I went to Chicago, I worked for two summer months in 1937 for Eastern Airlines at the Philadelphia airport - a job which my older brother Arthur, who was employed by that airline, helped me obtain. The job allowed me to save some money and also allowed me free air travel to Chicago. That helped a lot since my stipend as a teaching assistant at Northwestern was only $50 a month for a nine-month academic year. When I arrived in Chicago, it had already been arranged for me to share a room with two more advanced graduate students. Living in Chicago was quite a change from living in the Carolinas. When I would walk to work in the winter from our rooming house, which was about a mile from the medical school, the chill wind whipping in from Lake Michigan along Chicago Avenue was quite an experience for a Southern boy.

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