1. Edmond H Fischer Edmond H Fischer. Edmond H Fischer (1920) American biochemist whowas the corecipient with Edwin G. Krebs of the 1992 Nobel Prize http://www.nobel-winners.com/Medicine/edmond_fischer.html

Edmond H Fischer Edmond H Fischer American biochemist who was the corecipient with Edwin G. Krebs of the 1992 Nobel Prize for Physiology or Medicine for their discoveries concerning reversible phosphorylation, a biochemical mechanism that governs the activities of cell proteins. The son of Swiss parents, Fischer earned a Ph.D. in chemistry from the University of Geneva in 1947 and conducted research there until 1953. That year he went to the United States, where he joined Krebs on the faculty of the University of Washington, Seattle. He became a full professor there in 1961. Fischer and Krebs made their discoveries in the mid-1950s while studying reversible phosphorylation i.e., the attachment or detachment of phosphate groups to cell proteins. The two men were the first to purify and characterize one of the enzymes (phosphorylase) involved in the process of phosphorylation. They also discovered the enzymes that catalyze the attachment and detachment of phosphate groups, known as protein kinases and phosphatase, respectively. In the decades following these initial discoveries, scientists were able to identify many other enzymes that regulate specific processes in cells, leading to explanations of the mechanisms controlling basic activities in all living cells. Main Page About Us The Nobel Foundation . External sites are not endorsed or supported by

2. WIEM: Fischer Edmond fischer edmond h. (1920), biochemik amerykanski. Od 1956 profesor Universityof Washington w Seattle. fischer edmond h. (1920-), biochemik amerykanski. http://wiem.onet.pl/wiem/00217d.html

WIEM 2004 - zobacz now± edycjê encyklopedii! Kup abonament i encyklopediê na CD-ROM, sprawd¼ ofertê cenow±! Oferta specjalna abonamentów dla szkó³ i instytucji! Uwaga! Przedstawione poni¿ej has³o pochodzi z archiwalnej edycji WIEM 2001! Prace redakcyjne nad edycj± 2001 zosta³y zakoñczone. Zapraszamy do korzystania z nowej, codziennie aktualizowanej i wzbogacanej w nowe tre¶ci edycji WIEM 2004 Biologia, Chemia, Medycyna, Stany Zjednoczone Fischer Edmond Fischer Edmond H biochemik amerykañski. Od 1956 profesor University of Washington w Seattle. Od 1972 cz³onek Amerykañskiej Akademii Umiejêtno¶ci i Nauk w Bostonie, od 1973 Narodowej Akademii Nauk Stanów Zjednoczonych. W latach 50. wyodrêbni³ i zbada³ enzymy fosforylizuj±ce i defosforylizuj±ce bia³ka proste . W 1988 udowodni³, ¿e niektóre bia³ka limfocytów maj± cechy enzymów defosforylizuj±cych, co doprowadzi³o do odkrycia mechanizmu regulacji procesów ¿yciowych komórek , m.in. aktywacji odpowiedzi immunologicznej. Nagroda Nobla w 1992 w dziedzinie medycyny (z E.G. Krebsem

3. Edmond Fischer Edmond H. Fischer. Edmond H. Fischer says winning the prize can be abizarre business that catches you off guard. The first question http://www.washington.edu/alumni/columns/march98/fischer.html

Edmond H. Fischer Edmond H. Fischer says winning the prize can be "a bizarre business that catches you off guard. "The first question is: `Why us?' There are so many brilliant people working, including ones we've recommended." For a decade, he and Krebs had been among the thousand scientists asked to submit nominations for the prize. "If you get a gold medal in the Olympics, you know why. You came out first," he says. "In science, it's so different. You do your thing, working without thinking about this or any other award. Then all of the sudden in the middle of the night you get a call." That's how it happened for Fischer. He'd just returned from a trip to Italy in October 1992, when the telephone rang in the dark and woke him from a deep, jet-lagged sleep. An unfamiliar voice asked, "Are you Dr. Fischer?" "My first thought was, `Who is this guy? Does he want to sell me stocks, or replace the gutters on the house?' " "Are you Dr. Fischer from the University of Washington medical school?" the voice asked. " `Yeah,' I said. `Whaddya want?' `Congratulations,' said the voice. `This is CBS in New York. You've just won the Nobel Prize, along with Dr. Edwin Krebs.' "At first I didn't believe it," says Fischer. "But the moment he mentioned Ed, I woke up. I put the lights on. It was 3:45 a.m. As soon as I put the phone down, it rang again."

4. Nobelprizewinners In Lindau / Nobelpreisträger In Lindau Translate this page King Carl XVI Gustaf of Sweden. Ernst Otto fischer edmond h. FischerIvar Giaever. ?Das Zusammentreffen mit den Studenten ist fast http://www.nobelpreistraegertreffen.de/

am Bodensee wissenschaftlichen Nachwuchs Nobelprizewinners in Lindau on Lake Constance The annual meetings with young scientists Stiftung Lindauer Nobel- Bodensee Dialog der Generationen Foundation Lindau Nobel- prizewinners Meetings at Lake Constance Dialogue between the generations Donations/Spenden Intellectual excellence Gipfel des Geistes Opportunity for young scientists ... Lindau - wo sonst ? Intellectual excellence Gipfel des Geistes Titelbild / Title pictures: Insel Lindau / The island town of Lindau Albert Schweitzer mit Studenten / with students Insel Mainau / The island of Mainau Antony Hewish Klaus von Klitzing William N. Lipscomb Opportunity for young scientists Nachwuchs Since 1952, top students and scientific staff at research institutes in Germany and abroad have been invited to Lindau as a reward for the quality of their work. They are chosen from academic institutions and foundations and from lecturers at universities all over the world. By the year 2000, over 20000 students and young scientists had taken part at the Lindau meetings. Up to now, it was mainly European establishments, but the proportion of young people from other countries, particularly the USA, is increasing all the time. The organizers do their best to enable people from Asia and other continents to take part in the meetings. This is made possible by donors and sponsors who finance travel and accommodation costs or pay the participation fees.

5. Edmond H. Fischer - Autobiography edmond H. fischer – Autobiography. Memories of my early childhoodare clouded with uncertainties because I was essentially separated http://www.nobel.se/medicine/laureates/1992/fischer-autobio.html

Another important event marked my High School days: I was admitted to the Geneva Conservatory of Music. I had heard Johnny Aubert give an unforgettable rendition of Beethoven's 5th Piano Concerto. I decided on the spot that I wanted to study with him. After an audition in which I nervously presented Mendelssohn's Rondo Capriccioso and Chopin's A-maj. Polonaise, he took me on, and that spelled the beginning of many enthralling years. Music had always played an important part in my life, to such an extent that I even wondered whether I should not make a career of it. But finally I thought it better to keep music purely for pleasure. It was my goal to become a microbiologist but Fernand Chodat, the Professeur of Bacteriology, argued that there was little future in that field, which was probably the case in Switzerland at that time. He advised me to get a diploma in Chemistry saying that, in any case, test tubes were of more use than a microscope to modern microbiologists. A. oryzae

6. Fischer, Edmond H. fischer, edmond H. ( b. April 6, 1920, Shanghai, China), American biochemist who was the corecipient with Edwin The son of Swiss parents, fischer earned a Ph.D http://www.britannica.com/nobel/micro/210_2.html

Fischer, Edmond H. (b. April 6, 1920, Shanghai, China), American biochemist who was the corecipient with Edwin G. Krebs of the 1992 Nobel Prize for Physiology or Medicine for their discoveries concerning reversible phosphorylation, a biochemical mechanism that governs the activities of cell proteins. The son of Swiss parents, Fischer earned a Ph.D. in chemistry from the University of Geneva in 1947 and conducted research there until 1953. That year he went to the United States, where he joined Krebs on the faculty of the University of Washington, Seattle. He became a full professor there in 1961. Fischer and Krebs made their discoveries in the mid-1950s while studying reversible phosphorylation i.e., the attachment or detachment of phosphate groups to cell proteins. The two men were the first to purify and characterize one of the enzymes (phosphorylase) involved in the process of phosphorylation. They also discovered the enzymes that catalyze the attachment and detachment of phosphate groups, known as protein kinases and phosphatase, respectively. In the decades following these initial discoveries, scientists were able to identify many other enzymes that regulate specific processes in cells, leading to explanations of the mechanisms controlling basic activities in all living cells.

7. Fischer, Edmond H. Search Biographies Bio search tips fischer, edmond H. fischer, edmond H. 1920, American biologist, b http://www.infoplease.com/cgi-bin/id/A0818756

HOTWORDS CITE PRINT EMAIL in All Infoplease Almanacs Biographies Dictionary Encyclopedia Home Almanacs Atlas Dictionary ... D-Day Infoplease Tools Periodic Table Conversion Tool Perpetual Calendar Year by Year ... Site Map Also from Infoplease Search Infoplease Info search tips Search Biographies Bio search tips Encyclopedia Fischer, Edmond H. Fischer, Edmond H., Krebs discovered a biological regulatory mechanism, reversible protein phosphorylation, that affects nearly all human cells. For their work, Krebs and Fischer shared the 1992 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, Fischer-Dieskau, Dietrich Fischer, Emil Related content from HighBeam Research on: Edmond H. Fischer Research on cell-control path gains Nobel. (Edmond H. Fischer and Edwin G. Krebs win Nobel Prize in Medicine or Physiology) (Science News) U.S. Pair Wins Nobel for Cell Studies (Newsday) Nobel Prizes in Physiology or Medicine. (United Press International) NOBEL PRIZES IN PHYSIOLOGY OR MEDICINE (United Press International) Two decades of Nobel Medicine Prize winners (AP Online) This Week's Letters (Science) Heart Beat.(Suburban Living)

8. Fischer, Edmond H. The Columbia Encyclopedia, Sixth Edition. 2001 The Columbia Encyclopedia, Sixth Edition. 2001. fischer, edmond H. 1920–,American biologist, b. Shanghai, China. As researchers at the Univ. http://www.bartleby.com/65/fi/FischerEH.html

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9. Edmond H. Fischer 1920 - Edwin G. Krebs 1918 Proteins are involved in most cell functions, and in most body functions such as digestion and movement. Because of proteins' important and varied functions, they are closely regulated by the body through enzymes. where one will end up." edmond H. fischer, Les Prix Nobel, 1992. edmond fischer was born in Shanghai http://history.nih.gov/exhibits/rodbell/1_Fischer_Krebs.htm

P roteins are involved in most cell functions, and in most body functions such as digestion and movement. Because of proteins ' important and varied functions, they are closely regulated by the body through enzymes . The enzymes fine tune the working of a protein by attaching one or more phosphate groups to it. This is called "phosphorylation." Fischer and Krebs first purified and described an enzyme which regulates proteins by removing phosphate groups from the protein-"reversible protein phosphorylation." They did this by studying how muscles get energy to contract. Reversible protein phosphorylation affects nearly all bodily processes such as blood pressure, brain signals, and immune responses to several diseases, including cancer. For information about Fischer and Krebs' work, see www.nobel.se/medicine/laureates/1992/press.html

10. Medicine 1992 edmond H. fischer, Edwin G. Krebs. 1/2 of the prize, 1/2 of the prize. edmond H.fischer Autobiography Nobel Lecture Banquet Speech Interview Other Resources. http://www.nobel.se/medicine/laureates/1992/

The Nobel Prize in Physiology or Medicine 1992 "for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism" Edmond H. Fischer Edwin G. Krebs 1/2 of the prize 1/2 of the prize Switzerland and USA USA University of Washington Seattle, WA, USA University of Washington Seattle, WA, USA b. 1920 (in Shanghai, China) b. 1918 The Nobel Prize in Physiology or Medicine 1992 Press Release Presentation Speech Illustrated Presentation ... Other Resources The 1992 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: SITE FEEDBACK CONTACT TELL A FRIEND Last modified June 16, 2000 The Official Web Site of The Nobel Foundation

11. Index Of Nobel Laureates In Medicine Fibiger, Johannes Andreas Grib, 1926. Finsen, Niels Ryberg, 1903. fischer,edmond H. 1992. Fleming, Sir Alexander, 1945. Florey, Lord Howard Walter,1945. http://almaz.com/nobel/medicine/alpha.html

ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Medicine We always welcome your feedback and comments

12. Fischer, Edmond H. Encyclopaedia. Shopping. Ahha. Kanoodle. Findwhat. Summary. Top. Encyclopaedia. F. Fer. fischer, edmond H. NeedMoreBeer.com. Free HTML Editor. Cheap Web Hosting. Free Search Toolbar. Website Promotion. fischer, edmond H. Website Promotion. fischer, edmond H. www.trellian.com Still searching the hard way http://www.slider.com/Enc/F/Fer/FischerEH.htm

The Web Encyclopaedia Shopping Ah‑ha ... Index The Web Encyclopaedia Shopping Ah-ha Kanoodle Findwhat Summary Top Encyclopaedia F Fer ... NeedMoreBeer.com Fischer, Edmond H. Still searching the hard way? Try the Free Slider Search Toolbar and spend less time searching!! www.trellian.com Sponsored Link 1920–, American biologist, b. Shanghai, China. As researchers at the Univ. of Washington in Seattle, Fischer and Edwin G. Krebs discovered a biological regulatory mechanism, reversible protein phosphorylation, that affects nearly all human cells. For their work, Krebs and Fischer shared the 1992 Nobel Prize in Physiology or Medicine. Slider in: Espa±ol Deutsch Dansk Nederlands ... Download the FREE Slider.com Search Toolbar!

13. Fischer, Edmond H. --  Britannica Student Encyclopedia fischer, edmond H. Britannica Student Encyclopedia. To cite this page MLAstyle fischer, edmond H.. Britannica Student Encyclopedia. 2004. http://www.britannica.com/ebi/article?eu=335250&query=fischer, joschka&ct=ebi

14. Fischer, Edmond H. fischer, edmond H. fischer, edmond H. 1920, American biologist, b. Shanghai, China. As researchers at the Univ. of Washington in Seattle, fischer and Edwin G. http://www.factmonster.com/ce6/people/A0818756.html

Encyclopedia Fischer, Edmond H. Fischer, Edmond H., Krebs discovered a biological regulatory mechanism, reversible protein phosphorylation, that affects nearly all human cells. For their work, Krebs and Fischer shared the 1992 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, Fischer-Dieskau, Dietrich Fischer, Emil Print this page Cite this page AD AD AD ADS Link to Fact Monster Add Fact Monster search to your site ... Privacy Brought to you by:

15. Fischer, Edmond H. fischer, edmond H. (1920). Memories of my early childhood are cloudedwith uncertainties because I was essentially separated from http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/F/Fischer1/Fisch

Fischer, Edmond H. At age 7, my parents sent my two older brothers and me to La Châtaigneraie, a large Swiss boarding school overlooking Lake Geneva. My oldest brother, Raoul, was the first to leave to attend the ETH, the Swiss Federal Polytechnical Institute in Zürich where he was awarded a degree in engineering. My brother Georges went to Oxford and read law. In 1935, I entered Geneva's all boys Collège de Calvin from which I obtained my Maturité Fédérale four years later, even as the specter of World War II loomed evermore menacing. While in school, I formed a lifelong friendship with my classmate Wilfried Haudenschild who dazzled me with his tinkering abilities, off-the-wall ideas and mechanical inventiveness. Together we decided that one of us should go into the Sciences and the other into Medicine so that we could cure all the ills of the world. Another important event marked my High School days: I was admitted to the Geneva Conservatory of Music. I had heard Johnny Aubert give an unforgettable rendition of Beethoven's 5th Piano Concerto. I decided on the spot that I wanted to study with him. After an audition in which I nervously presented Mendelssohn's Rondo Capriccioso and Chopin's A-maj. Polonaise, he took me on, and that spelled the beginning of many enthralling years. Music had always played an important part in my life, to such an extent that I even wondered whether I should not make a career of it. But finally I thought it better to keep music purely for pleasure.

16. Edmond H. Fischer, PhD, Joins GeneProt(TM), Inc.'s Scientific Advisory Board As edmond H. fischer, PhD, Joins GeneProt(TM), Inc.'s Scientific Advisory Board As Second Nobel Laureate today the appointment of edmond H. fischer, PhD, to the company's Scientific http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/09-27

17. Fischer, Edmond Henri http://www.cartage.org.lb/fr/themes/Biographies/mainbiographie/F/Fischer/Fischer

Fischer, Edmond Henri (Shanghai, 1920) Biochimiste américain. Edmond H. Fischer est diplômé de l'université de Genève en 1947. Il y travaille comme enseignant de 1950 à 1953, date à laquelle il accepte un poste à l'université de Washington, à Seattle. C'est là qu'il rencontre Edwin G. Krebs , avec qui il travaillera pendant 30 ans. Dans les années 1950, les deux chercheurs orientent leurs études sur la contraction musculaire. Alors qu'ils étudient le métabolisme du glycogène dans les muscles, ils comprennent le mécanisme de phosphorylations et de déphosphorylations, un processus fondamental pour réguler l'activité de diverses enzymes. Ils isolent et décrivent la première protéine-kinase, une enzyme qui transfère le phosphate de l'acide adénosine triphosphorique (ATP) vers les protéines. Ils découvrent ensuite la phosphatase, l'enzyme qui supprime le phosphate, complétant ainsi le cycle qui permet à l'ATP de libérer l'énergie nécessaire à diverses fonctions, notamment à la contraction musculaire. En 1992, Fischer et Krebs partagent le prix Nobel de médecine ou physiologie.

18. PNRI | About Edmond H. Fischer, Ph. D. 2000, About edmond H. fischer, Ph.D. edmond H. fischer, Ph. D. (clickfor fullsized image). Click for full-sized image. Dr. edmond http://www.pnri.org/seminars/lang-vir/fischer.html

Seminar Schedule Annual Langerhans-Virchow Lecture Dr. Fischer gave the First Annual Langerhans-Virchow Lecture , in 2000 About Edmond H. Fischer, Ph.D. Click for full-sized image Dr. Edmond H. Fischer was born in Shanghai in 1920. At age 7, he went to Switzerland where he carried out all his studies, receiving B.S. degrees in chemistry and biology and a Ph. D. degree in organic chemistry from the University of Geneva. After a few years as a Fellow of the Rockefeller Foundation and a Private Docent at the University of Geneva, he spent a year at the California Institute of Technology. In 1953, he joined the Department of Biochemistry at the University of Washington, where he is now Professor Emeritus. Within six months of his arrival in Seattle, he initiated his collaborative studies with Edwin G. Krebs on the regulation of glycogen phosphorylase. Fischer and Krebs went on to define the series of reactions in the cascade leading to the activation/inactivation of this enzyme as triggered by hormones and calcium. Since then, they have been working on the regulation of different cellular processes by reversible protein phosphorylation. Toward the end of his career, Dr. Fischer"s laboratory had been particularly interested in the identification, characterization and regulation of a variety of intracellular and receptor protein tyrosine phosphatases and their involvement in signal transduction, cell cycle progression and transformation. Dr. Fischer has served on numerous scientific advisory boards, including those for NIH and NSF, the Muscular Dystrophy Association, the Friedrich Miescher Institute of CIBA-GEIGY, the Biozentrum of the University of Basel, the Basel Institute for Immunology, the Scientific Governors of the Scripps Research Institute and the Weizmann Institute of Science.

19. PNRI | The First Annual Langerhans-Virchow Lecture edmond H. fischer, Ph. D. (click for fullsized image). Click for full-sized image.edmond H. fischer, Ph.D. Dr. edmond H. fischer was born in Shanghai in 1920. http://www.pnri.org/seminars/lang-vir/2000/

Seminar Schedule Annual Langerhans-Virchow Lecture The First Annual Langerhans-Virchow Lecture Click for full-sized image Edmond H. Fischer, Ph.D. Professor Emeritus of Biochemistry University of Washington " Cell Signaling by Tyrosine Phosphorylation" This lecture took place on Wednesday, Feb. 23, 2000 Glaser Auditorium Swedish Hospital 727 Broadway Seattle, WA 98122 more about Dr. Fischer Rudolf Virchow and Paul Langerhans made key discoveries in the mid 19 th more about Langerhans and Virchow Top of Page Home About ... Search

20. MSN Encarta - Fischer, Edmond H. Sign in above. fischer, edmond H. fischer, edmond H. (1920 ), American biochemistand Nobel Prize winner, born in Shanghai, China, of French parents. http://encarta.msn.com/encyclopedia_761582609/Fischer_Edmond_H.html

MSN Home My MSN Hotmail Shopping ... Money Web Search: logoImg('http://sc.msn.com'); Encarta Subscriber Sign In Help Home ... Upgrade to Encarta Premium Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Fischer, Edmond H. Fischer, Edmond H. (1920- ), American biochemist and Nobel Prize winner, born in Shanghai, China, of French parents. Fischer received a Ph.D. degree in... Related Items discovery of ATP Multimedia Selected Web Links Edmond H. Fischer [Nobel Foundation] 1 item Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Fischer, Edmond H.

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