61. HHMI News: Researchers Develop Mouse Model Of Rett Syndrome Researchers Develop Mouse Model of rett syndrome. “As development progresses, what we encounter our experiences may also change how the brain responds. http://www.hhmi.org/news/zoghbi5.html

RESEARCH NEWS RESEARCH NEWS GRANT ANNOUNCEMENTS SCIENCE EDUCATION NEWS INSTITUTE NEWS ... HHMI HOME ALSO OF INTEREST Rett Syndrome Traced to Defective Gene "Silencer" HHMI Bulletin: Huda Zoghbi Profile When the Brain Fails Teasing Out the Early Steps of Neurodegeneration Gene Triggers Formation of Sensory Cells in the Ear ... Download this story in Acrobat PDF format. (requires Acrobat Reader Researchers Develop Mouse Model of Rett Syndrome “As development progresses, what we encounter our experiences may also change how the brain responds. This may account for individual variation in disease severity,” said HHMI investigator Huda Zoghbi. By studying gene mutations in patients with the complex set of behavioral and neurological symptoms that accompany Rett syndrome, Howard Hughes Medical Institute investigator Huda Zoghbi and her colleagues at Baylor College of Medicine have designed a mouse model that faithfully recapitulates the disease down to its distinctive hand-wringing behavior. The development of the mouse, reported in the July 18, 2002 issue of the journal

62. Defective Gene Linked To Rett Syndrome Defective Gene Linked To rett syndrome. rett syndrome is the first human disease found to be caused by mutations in this type of gene. http://www.applesforhealth.com/defectivegene1.html

Volume 1, Number 21 - October 22, 1999 Search Applesforhealth.com Search The Web or super search the health web Select A Search Topic Clinical Trials Doctors Dentists Pediatric Dentists Hospitals Chiropractors Eye Doctors Alternate Health Prof. Drug Interactions Medications Diseases Poisons Injuries Mental Health Medical Tests Surgical Procedures Children's Health Men's Health Women's Health Parenting Senior Health Google Search Yahoo Health News Medical Search Health Library Health Topics Gyms Currency Converter Travelers' Health People Word Finder Thesaurus Search Zip Codes Maps Small Business Help Home Repair Small Business Health Insurance library of health Select a Focus Topic Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Eye Care Fertility Fitness Gastrointestinal Health Hair Loss Headache Health care Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Overview Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Health Women's Health Click Here To Subscribe To Applesforhealth.com For FREE

63. Rett Syndrome Information rett syndrome. International rett syndrome Association (IRSA) Organization calling for rett syndrome research and education. A Child With rett syndrome. http://www.geocities.com/HotSprings/Spa/3247/rett_syndrome.html

Rett Syndrome International Rett Syndrome Association (IRSA) Organization calling for Rett syndrome research and education. Provides information and support to patients and their families. http://www2.paltech.com/irsa/irsa.htm National Academy for Child Development, Inc. An international organization dedicated to helping children and adults cope with developmental issues. http://www.nacd.org/index.html One to One Individualized Therapeutic Recreation A long list of therapeutic recreation links, including links for Rett Syndrome. http://www.erols.com/dawnie1/oneto1.htm Our Rett Syndrome Page Another great resource for finding information about Rett Syndrome. http://pages.prodigy.com/DebbieSchilling/irsg.htm Rett Syndrome Has technical medical information on Rett Syndrome. http://www.icondata.com/health/pedbase/files/RETTSYND.HTM Rett Syndrome Great resource page for information on Rett Syndrome, how to chat with others, personal accounts and more. http://www.familyvillage.wisc.edu/lib_rett.htm Rett~Angels Gallery A photo gallery of girls suffering with Rett Syndrome and links to their websites.

64. Rett Syndrome rett syndrome. I decided to do rett syndrome for my Web Paper because it is a disease that has effected my family directly over the past seventeen years. http://serendip.brynmawr.edu/biology/b103/f01/web1/charamella.html

This paper was written by a student in a course at Bryn Mawr College, and reflects that student's research and thoughts at the time the paper was written. Like other things on Serendip , the paper is not intended to be "authoritative" but is instead provided to encourage others to themselves learn about and think through subjects of interest, and, by providing relevant web links, to serve as a "window" to help them do so. Web links were active as of the time the paper was posted but are not updated. Biology 103 2001 First Web Report On Serendip Rett Syndrome Deb Charamella Rett Syndrome randomly effects girls 1 in 10,000 girls. There have been a few reported cases in males however males do not live past birth. Many girls have been misdiagnosed because Rett Syndrome is closely related to other disorders, such as autism, ataxic cerebral palsy, atypical Angelman's syndrome, mitochondria disease, spinocerebellar among others. The reason that Rett syndrome is easily misdiagnosed, is because there is such a wide range in functioning among girls with Rett Syndrome. Rett Syndrome is diagnosed by the following: -Normal development until 6-18 months -Normal head circumference at birth followed by slowing of head growth -Loss of verbal language -Purposeful hand use is replaced by stereotypical hand movements such as hand clapping, constant hand wringing, or other midline hand repetitive hand movement

65. Rett Syndrome rett syndrome. What is it? rett syndrome is a severe progressive neurological disorder that affects only females. The symptoms http://www.hmc.psu.edu/childrens/healthinfo/r/rhett.htm

66. AllRefer Health - Rett Syndrome rett syndrome information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, tests, support groups, complications http://health.allrefer.com/health/rett-syndrome-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Rett Syndrome Rett Syndrome Definition Treatment Expectations or Prognosis Complications ... Go To Main Page Definition Rett syndrome is an inherited disorder that affects only females. The syndrome causes mental retardation and developmental degeneration. Rett Syndrome is a severe progressive neurological disorder that causes marked developmental regression, especially in the areas of expressive language and hand use. It occurs only in girls. The gene associated with this disorder was recently identified on the X-chromosome. This gene encodes methl-CpG-binding protein 2 (MeCP2), which regulates synthesis (transcription) of various other proteins. Synthesis of incorrect proteins, due to mutations in the gene, causes damage in the maturing brain. The severity of the disease is linked to specific types of mutation.

67. HBOT, Rett Syndrome, & Cerebral Palsy application as a treatment for brain injuries, and the question of its application to developmental disabilities including cerebral palsy and rett syndrome. http://hbot.freeservers.com/

HBOT for Developmental Disabilities including RS and CP by Earl M. Williams, Ph.D. New Location update: Personal Note FAQ , and 7/8/01 update: see links to the latest analysis of the Montreal study of HBOT and cerebral palsy (a French site, so scroll down to the "Version anglaise" link starting with "Analysis of the results of..."), and the second Symposium on Cerebral Palsy and the Brain Injured Child (July 25-28, 2001) In Spring 1999, I wrote an extensive literature review paper on hyperbaric oxygen therapy (HBOT) , its demonstrated application as a treatment for brain injuries , and the question of its application to developmental disabilities including cerebral palsy and Rett Syndrome . The paper includes a large number of Internet links and almost 100 scientific references. The goal of the paper is to clearly synthesize important HBOT information that has not previously been presented in one place: on HBOT, the research showing its effectiveness for brain injury, the rationale for its applicability to additional neurological conditions, HBOT treatment protocols, and the data on each of its purported side effects (seen only at high pressures). As of July 2000 this paper is no longer fully current, but I hope to be able to revise it at some point. For now, the many Internet links and references in the paper will lead you to more current information. In particular, see the new 3rd edition of the "Textbook of Hyperbaric Medicine" by K. K. Jain ( click here to view publisher information).

68. Rett Syndrome rett syndrome. Who to Contact Site Index. rett syndrome. A neurodevelopmental disorder that affects females, rett syndrome http://www.ggc.org/Diagnostics/Molecular/rett_syndrome.htm

Rett Syndrome Who to Contact Site Index Rett Syndrome A neurodevelopmental disorder that affects females, Rett syndrome is associated with cortical atrophy, stereotypical hand movements and severe mental deficiency. With an incidence of 1 in 10,000 - 15,000, it is one of the most common causes of mental retardation in females. Rett syndrome is characterized by loss of acquired skills after a period of normal development in infancy. Mutations in X-linked methyl-CpG binding protein 2 (MECP2) which cause Rett syndrome include both nonsense (R168X and R255X) and missense (R106W and R306C) mutations. Genetic analysis for Rett Syndrome at the Greenwood Genetic Center includes complete sequencing of the entire coding region of the MECP2 gene. Specimen requirements : 5 ml of peripheral blood collected in an EDTA (lavender top) Vacutainer tube is preferred. The minimal blood needed for reliable DNA isolation is 3 ml. If necessary, ACD solution A Vacutainer tubes (yellow top) may be submitted. Please contact the laboratory for more information. Transport : Please contact the Molecular Diagnostic Lab Coordinator (1-800-473-9411) for shipping information. The specimen should be kept at room temperature and delivered via overnight shipping. FedEx is preferred. If shipment is delayed by one or two days, the specimen should be refrigerated and shipped at room temperature. Do not freeze the specimen. Samples collected on Friday can be safely designated for Monday delivery. However, our lab does accept specimens on Saturdays.

69. Rett Syndrome Association About the Charities rett syndrome Association UK rett syndrome is a complex lifelong neurological disorder. What does the rett syndrome Association UK do? http://www.jeansforgenes.com/2_about/2085_aboutrett.php

Rett Syndrome Association UK What does the Rett Syndrome Association UK do? The Rett Syndrome Association UK funds research, and gives help, advice, information and support to parents, carers, siblings and professionals. Jeans for Genes donations in 2004 will help fund a research team which is studying the link between the genetic make-up of a person with Rett syndrome and the conditions physical characteristics. Results will lead to an improved accuracy of genetic counselling for families and of decisions made on the basis of this. A second project being funded is exploring the possibility of therapeutic approaches to Rett syndrome and especially whether these could delay, prevent or even reverse the onset of the condition. Back Visit www.rettsyndrome.org.uk

70. The Rett-Syndrome Julia promotes the. International rett syndrome Association . What is the rett syndrome? The International rett syndrome Association. http://www.juliaroberts.de/x-rett.htm

Julia promotes the "International Rett Syndrome Association" What is the Rett Syndrome? Rett Syndrome is a neurological disorder seen almost exclusively in females, and found in a variety of racial and ethnic groups worldwide. The child with Rett Syndrome usually shows an early period of apparently normal or near normal development until 6-18 months of life. A period of temporary stagnation or regression follows during which the child loses communication skills and purposeful use of hands. Soon, stereotyped hand movements, gait disturbances, and slowing of the rate of head growth become apparent. The International Rett Syndrome Association Please visit the homepage of the organisation to learn more about the Rett Syndrome and the efforts of the " International Rett Syndrome Association ". What´s Julia´s participation? Julia appears in a documentary about the Rett Syndrome titled "Silent Angels". The shooting took place in Seattle, Los Angeles, Baltimore and New York. Julia is narrator of the project. The documentary aim is to discuss Rett Syndrome through the eyes of several families and with the assisstence of geneticists and other researchers. At the moment there are only 4.178 Rett cases identified in the whole world. But it must be much more. This film wants to find those missing or misdiagnosed kids.

71. Rett Syndrome rett syndrome Important It is possible that the main title of the report rett syndrome is not the name you expected. Please check http://my.webmd.com/hw/health_guide_atoz/nord182.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Quizzes, Calculators Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Medical Library Choose a Topic Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... For a Complete Report Rett Syndrome Important It is possible that the main title of the report Rett Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Autism, Ataxia, and Loss of Purposeful Hand Use RS RTS Disorder Subdivisions None General Discussion Rett Syndrome is a rare neurodevelopmental disorder that appears to occur almost exclusively in females but can occur rarely in males. Infants and children with the disorder typically develop normally until about 7 to 18 months of age, when they may begin to lose previously acquired skills (developmental regression), such as purposeful hand movements and the ability to communicate. Additional abnormalities typically include slowing of head growth (acquired microcephaly); development of distinctive, uncontrolled (stereotypic) hand movements, such as hand clapping, rubbing, or "wringing"; and impaired control of voluntary movements required for coordination of walking (gait apraxia). Affected children also typically develop autistic-like behaviors, breathing irregularities, feeding and swallowing difficulties, growth retardation, and episodes of uncontrolled electrical activity in the brain (seizures).

72. Rett Syndrome rett syndrome is a progressive neurological disorder in which individuals exhibit reduced muscle tone, autisticlike behavior, hand movements consisting mainly http://healthlink.mcw.edu/article/921961093.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: autistic Receive Health Link via email! Subscribe now >> Rett Syndrome Rett syndrome is a progressive neurological disorder in which individuals exhibit reduced muscle tone, autistic-like behavior, hand movements consisting mainly of wringing and waving, loss of purposeful use of the hands, diminished ability to express feelings, avoidance of eye contact, a lag in brain and head growth, gait abnormalities, and seizures. Hypotonia (loss of muscle tone) is usually the first symptom. The syndrome affects approximately 1 in every 10,000-15,000 live female births, with symptoms usually appearing in early childhood between ages 6 and 18 months. The cause of Rett syndrome is unknown. There is no cure for Rett syndrome; however, there are several treatments options. These include treatments for the orthopedic and learning disabilities and seizures that may occur in individuals with Rett syndrome. Some children may require special nutritional programs to maintain adequate weight. In spite of the severe impairments that characterize this disorder, the majority of individuals with Rett can be expected to reach adulthood, surviving at least into their 40s. However, the risk of death is increased. Sudden, unexplained death possibly from brainstem dysfunction with respiratory arrest often occurs.

73. Rett Syndrome rett syndrome. rett syndrome Association UK. International rett syndrome Association. The home page for the International rett syndrome Association. http://omni.ac.uk/browse/mesh/C0035372L0035372.html

low graphics Rett Syndrome other: Canavan Disease Cockayne Syndrome Hepatolenticular Degeneration Hereditary Central Nervous System Demyelinating Diseases ... Rett Syndrome Association UK Rett Syndrome Association UK is a registered charity which offers support to females affected by Rett Syndrome, as well as the carers of these girls and women. Rett Syndrome is a neurological disorder which occurs only in females and those affected are totally dependent on others for their needs. The Rett Syndrome Association UK (RSAUK) provides support for its members in a variety of ways such as, office help, self-support groups, contact supporters network, CarersLine and out of office hours contact numbers. This site provides details about these services, their newsletter, and information about the syndrome. Rett Syndrome Organizations, Nonprofit Great Britain Charities ... International Rett Syndrome Association The home page for the International Rett Syndrome Association. The site contains information about Rett (a neurological disorder seen almost exclusively in females), case studies, a discussion group for professionals and the parents of Rett syndrome girls, events, publications, news updates and research contacts. Rett Syndrome Organizations, Nonprofit

74. Special Child: Disorder Zone Archives - Rett Syndrome rett syndrome. Naomi CatfordRobinson. Features and Characteristics. rett syndrome is often mistaken for autism, cerebral palsy, and mental retardation. http://www.specialchild.com/archives/dz-002.html

Disorder Zone Archives Rett Syndrome Naomi Catford-Robinson Rebecca Morris Introduction Rett syndrome (RS) is a genetic disorder that is characterized by an initial period of normal development, followed by a loss of communication skills and purposeful hand movements. It is a disorder that is seen almost exclusively in females and occurs in a variety of racial and ethnic groups worldwide. RS has just recently been traced to a defective gene on the X chromosome called MeCP2. It is estimated that the incidence of RS is between 1 in every 10,000 to 15,000 live female births. Features and Characteristics Rett syndrome is often mistaken for autism, cerebral palsy, and mental retardation. However, no other condition has a period of rapid deterioration followed by stabilization and sometimes even improvements in autistic features, eye contact, and stereotypical hand movements. Since there is no form of laboratory testing for RS, diagnostic criteria and exclusionary criteria have been formed for the recognition of the syndrome. The following characteristics must be found in order to receive a diagnosis of RS: Normal development until approximately 6 to 18 months of age Normal head circumference at birth, followed by a slowed growth rate anywhere from 3 months to 4 years of age

75. Rett Syndrome rett syndrome. International rett syndrome Association. rett syndrome. rett syndrome. Rae Anne A Child With rett syndrome. RETT CENTER. Our rett syndrome Page. http://www.doctorpage.com/Diseases_and_Conditions/html/rett_syndrome.htm

Match: Any Terms All Terms Help Check out our new site format - CLICK HERE! Rett syndrome International RETT Syndrome Association Rett Syndrome Rett Syndrome Rae Anne A Child With Rett Syndrome ... doctorpage.com

76. Autism And Rett Syndrome; The Pevsner Lab Autism and rett syndrome. Introduction. Autism Society of America. Jypsy s Autism Links. rett syndrome Background. rett syndrome affects girls almost exclusively. http://pevsnerlab.kennedykrieger.org/autism_rett.htm

Home DRAGON SNOMAD Bioinformatics ... Publications Autism and Rett Syndrome Introduction Autism and Rett Syndrome are devastating, lifelong neurological disorders that are classified as pervasive developmental disorders (sometimes abbreviated PDD). Autism and Rett Syndrome are characterized clinically by severe, pervasive impairment in communication skills and in reciprocal social interaction skills. Stereotyped behavior and interests are typical. In many cases, autism and Rett Syndrome are accompanied by mental retardation as well as seizures. These disorders cause significant hardships for the affected children and adults, as well as their families, schools and communities. Today, the diagnosis of autism and related pervasive developmental disorders such as Asperger's Syndrome is based upon clinical criteria. There are no known biological causes. There are very few proven neurochemical, genetic, neuroanatomical, neurophysiological, structural, metabolic, or other molecular differences between these patients and the normal population.

77. Rett Syndrome - Medical Dictionary Definitions Of Popular Medical Terms MedicineNet Home MedTerms medical dictionary AZ List rett syndrome. Advanced Search. rett syndrome is a most unusual disease because ONLY GIRLS have it. http://www.medterms.com/script/main/art.asp?articlekey=11960

78. Rett Syndrome Is Traced To A Surprising Genetic Culprit rett syndrome IS TRACED TO A SURPRISING GENETIC CULPRIT. That s why I think that this will probably be the predominant, if not only, gene for rett syndrome. . http://www.neurologyreviews.com/dec99/nr_dec99_RettSyn.html

Home Address Change Archives Return to table of contents R ETT S YNDROME I S T RACED TO A S URPRISING G ENETIC C ULPRIT a gene that participates in "silencing" numerous other genes at key points in development. The discovery has immediate implications for the diagnosis of developmentally impaired infants, as well as possible future implications for the development of effective treatments. Rett syndrome was first described in the German literature in 1966 by Dr. Andreas Rett, but received little attention in the United States until a 1983 paper by Dr. Bengt Hagberg and colleagues was published in the Annals of Neurology. The syndrome occurs almost exclusively in females, affecting approximately one of every 10,000 to 15,000 girls born in the world. Infants with Rett syndrome develop normally for the first six to 18 months, then motor skills and speech typically regress; walking is often delayed or accomplished with great difficulty. Perhaps the most striking feature, however, is the near-constant hand-wringing that is typical of the disorder. About 80% of children with Rett syndrome have seizures; also common are breathing irregularities, scoliosis, retarded growth, and EEG abnormalities. The recent research, published in the October issue of

79. Researchers Confirm Novel Form Of The Rett Syndrome Protein 203445-9233 rett syndrome Research Foundation Researchers confirm novel form of the rett syndrome protein. March 22, 2004 – Adrian http://www.eurekalert.org/pub_releases/2004-03/rsrf-rcn032204.php

Public release date: 22-Mar-2004 Contact: Monica Coenraads monica@rsrf.org Rett Syndrome Research Foundation Researchers confirm novel form of the Rett syndrome protein March 22, 2004 – Adrian Bird and Skirmantas Kriaucionis of the University of Edinburgh have discovered a novel form of the protein MeCP2. This alternate form, coined MeCP2 alpha, differs from the original only in the first 19 amino acids. Interestingly, Adrian Bird, Director of the Welcome Trust Centre for Cell Biology at Edinburgh University, found that MeCP2 alpha, is ten times more prevalent not only in the brain but also in other tissues. These findings are currently reported online in Nucleic Acids Research. Similar findings were reported yesterday in Nature Genetics online by Berge Minassian, a neurologist and scientist at Toronto's Hospital for Sick Children. Adrian Bird originally cloned the MECP2 gene in 1992 while in Vienna, Austria at the Institute for Molecular Pathology. In October of 1999 Huda Zoghbi of Baylor College of Medicine and the Howard Hughes Medical Institute announced that mutations in the MECP2 gene were the leading cause of Rett Syndrome (RTT). RTT is a severe neurological disorder diagnosed almost exclusively in girls. Children with RTT appear to develop normally until 6 to 18 months of age, when they enter a period of regression, losing speech and motor skills. Most develop repetitive hand movements, irregular breathing patterns, seizures and extreme motor control problems. RTT leaves its victims profoundly disabled, requiring maximum assistance with every aspect of daily living. There is no cure.

80. Study Offers New Insight Into Rett Syndrome rett syndrome is a major cause of mental retardation in girls. Although Study offers new insight into rett syndrome. Cambridge, Mass. – Rett http://www.eurekalert.org/pub_releases/2003-10/wifb-son102703.php

Public release date: 30-Oct-2003 Contact: Kelli Whitlock newsroom@wi.mit.edu Whitehead Institute for Biomedical Research Study offers new insight into Rett Syndrome Cambridge, Mass. – Rett Syndrome is a major cause of mental retardation in girls. Although researchers have identified the protein involved in the disease, its exact role remains a mystery. Now, a group of researchers from Children's Hospital Boston and Whitehead Institute of Biomedical Research have identified the protein's function, a discovery the scientists say could be the first significant advance in Rett Syndrome research in years. The study, reported in this week's issue of the journal Science, describes how the protein in question controls gene expression in normal central nervous system cells. Researchers suspect that mutations in the protein impair its ability to regulate genes during a critical stage of brain development. "We think that this deregulation may be responsible for some of the defects that we see in Rett patients," says Michael Greenberg, director of the Children's Hospital group and a lead author of the study. A neurological disorder causing mental retardation as well as cerebral-palsy and autism-like symptoms, Rett Syndrome affects one out of approximately 15,000 female babies worldwide. Current therapies, including medications that help prevent seizures, treat some of the symptoms but not the disease.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 4     61-80 of 112    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20