101. The Leukemia Lymphoma Society The leukemia Lymphoma Society, Glossary, Site. Find on Map. Experience it. more. •, The leukemia Cup Regatta. Setting sail for cures. more. SPONSORED BY, http://leukemia-lymphoma.org/

Glossary Site Find on Map Email: Password: Remember Me Not Yet Registered? HOME PATIENT SERVICES Newly Diagnosed ... Medical News: (Reuters) Study Supports Antibiotics Before Myelosuppressive Chemotherapy (Reuters) Bortezomib Superior to Standard Therapy for Relapsed Multiple Myeloma (Reuters) Thalidomide Seen Helpful in Treating Multiple Myeloma Press Releases: (Press Releases) Experts Share the Latest News on Myeloma Treatment (Press Releases) Statement on the Surgeon General's Report Linking Cigarette Smoking to Leukemia Society News: (Society Reports) U.S. Food and Drug Administration Approves First Effective Treatment for Myelodysplastic Syndrome More News CALENDAR April 27, 2004 - October 24, 2004 Join Us for The Nike 26.2 San Francisco, CA June 13, 2004 King's Trail Triathlon Maui, HI June 15, 2004 Myeloma: The Latest Treatment Options June 19, 2004 Mayor's Midnight Sun Marathon and Half Marathon Anchorage, AK June 22, 2004 Advances in Therapy: Update on Clinical Trials August 29, 2004 The Accenture Chicago Triathlon Chicago, IL

102. Leukemia Information And Resources Cancer survivor's resource with many links which touch on a number of related topics. http://www.geocities.com/leukemia_lymphoma/leukemia2.htm

The Current Time is Click here for the latest News Articles about leukemia, lymphoma, and other blood related cancers. (Source: Leukemia and Lymphoma Society) The following link directs you to a web page with links to prayer request message boards. Prayer Requests Leukemia Information and Resources Introduction Personal Stories The Diseases Childhood Leukemia ... Click here to visit my message board! You may navigate the website by clicking a link above, or by using the navigation links near the bottom of the pages. Click here to see a few pictures of myself, and read my short Bio. Please report any broken links HERE . Thank you. Sign My Guestbook View My Guestbook Visitors, click HERE to post a question or comment on the Message Board. Find Peer to Peer support at Cancer Survivors Network! A cancer support community provided through the American Cancer Society Introduction. Welcome and thank you for visiting my web page. My name is Michael Cook , and I am a survivor of Childhood Acute Lymphoblastic Leukemia. I was diagnosed in 1995 when I was 21 years old. I was treated at University of California San Francisco Comprehensive Cancer Center with chemotherapy, some surgeries, a short while on dialysis, and radiation. If you are a patient of, or know someone who is a patient of leukemia, lymphoma, Hodgkins disease, or multiple myeloma, then this web site may be of some benefit to you. My intention for building this web site is to provide supplemental information by listing links to other web sites dealing with leukemia, lymphoma, Hodgkins Disease, NHL, and a few other blood disorders and metabolism disorders. Also included are links to personal accounts from survivors, bone marrow programs, pain management, side effects, benefits and fund raisers, support groups, chemotherapy, radiation therapy, nutrition, glossaries, pharmaceuticals, and cancer treatment facilities.

103. Leukemia Cluster leukemia Cluster Hotline 1.888.608.4623. Churchill County (Fallon) Childhood leukemia Update. Final Report of the Expert http://health2k.state.nv.us/healthofficer/leukemia/fallon.htm

Leukemia Cluster Hotline: 1.888.608.4623 Churchill County (Fallon) Childhood Leukemia Update Final Report of the Expert Panel on Childhood Leukemia in Churchill County, Nevada 3.3.04 Final Report and Recommendations to NV State Health Division, from Expert Panel, 2.23.04 Centers for Disease Control and Prevention (CDC) Report (2-2003) Agency for Toxic Substances and Disease Registry (ATSDR) Studies ... Additional ATSDR Studies Background The cluster of childhood leukemia cases was brought to the attention of Nevada public health officials in the late summer of 2000, when it was learned that five cases of Acute Lymphocytic Leukemia (ALL) had been diagnosed in Churchill County within a few months of each other. The Health Division immediately consulted with the Centers for Disease Control and Prevention (CDC) on appropriate steps for an investigation. To date, fifteen children have been diagnosed with ALL and one with Acute Myelocytic Leukemia (AML), all of whom lived in Churchill County for varying lengths of time prior to diagnosis. Dr. Randall Todd, State Epidemiologist, noted that based on cases reported to the Nevada Central Cancer Registry, an average rate of Acute Lymphocytic Leukemia is about 3 childhood cases per 100,000 children.

104. Hairy Cell Leukemia Research Foundation The Hairy Cell leukemia Research Foundation is a nonprofit, all volunteer, patient run organization whose primary goal is to provide support, information. http://home.earthlink.net/~shanford/hcl.htm

Redirect to Hairy Cell Leukemia Research Foundation Home Page

105. Alex's Place - Update On Alex's Fight Against Acute Mylogenous Leukemia Update on 3 1/2 year old Alexandra Martini's three year fight against pediatric Acute Mylogenous leukemia. http://www.alexupdate.com

Thursday April 8, 2004 Hi Everyone, Just a quick update to let you know that Alex had the LP (lumbar puncture) on Tuesday and the results came back yesterday. Zero leukemia blasts in her CNS! At this point it's possible that the seizure was caused by whatever respiratory virus all four of us currently have. It also appears that the seizure triggered the increase in her White Blood Count (WBC). As of Tuesday her WBC was back down to normal range. Because of the virus, Alex is going to miss school all of this week and next week is Easter break. As long as there are no further complications she'll return the school after the break. Thanks again to everyone for helping us through yet another crisis. Take care. Todd Saturday April 3, 2004 @ 10 pm Hi Everyone, We're out of the hospital! Alex had an MRI today and although the calcifications (scarring) from her prior radiation and chemo treatments remain, there was nothing there to cause alarm. The doctors feel that she will remain stable as long as she remains on Depakote, an anti-seizure medication. What this means is that Alex will more than likely have to take Depakote for the rest of her life to avoid future seizures. The doctors also didn't feel it was necessary to do the LP (lumbar puncture) before we left the hospital today. We should know by Monday when it will be scheduled for.

106. Alternative Natural Health - Breakthrough - A Powerful Natural Nutritional Remed Discusses how natural trace elements in the diet can prevent cancers, Arthritis, MS, leukemia and most autoimmune diseases. http://www.truehealth.org

IN A NUTSHELL SUPREME HEALTH POISON FREE AGRICULTURE STABLE CLIMATES ... COMMENTARY All of the above subjects, plus the cosmic law of Progressive Complexity, the driving force of all Life, growth and evolution, in a nutshell. The complete natural range of the 72 trace elements in a daily serving of seafood [our daily food has 8] gets rid of most 'incurable' diseases and many cancers. Re-establishing the complete natural range of the 72 trace elements in agricultural soils [instead of today's paltry 8] results in a rich, abundant, permanently sustainable, totally poison free and supremely healthy agriculture. The massive decimation of the Earth's forests - 80% are gone - is driving our climates to the bitter extremes of lifeless desert climates. Reforesting the Earth will re-establish a vibrantly healthy biosphere, and end the greenhouse effect Commentary on major issues of our Times and Lives based upon the fundamental driving forces of Life and our Biosphere. a powerful natural remedy for many cancers and 'incurable' diseases - Arthritis, MS, Leukemia, most autoimmune diseases ... - and there is nothing to buy, no product is involved, and all the info is free for personal use only -

107. Leukemia leukemia / Myelodysplasia. 15 October 2003, copyright (c) 20012003 PathologyOutlines.com, LLC. Home Page. Microgranular variant of promyelocytic leukemia. http://pathologyoutlines.com/leukemia.html

Leukemia / Myelodysplasia Home Page PRINTER FRIENDLY PAGE Bold and underlined topics are hypertext links Excludes: leukemic phase of lymphoma, myeloproliferative disorders, chronic leukemias Table of Contents-Leukemia / Myelodysplasia Primary references AML: general classification t(8;21), t(V;17), ... acute panmyelosis with myelofibrosis ALL: general classification cytogenetics with cytoplasmic granules ... biphenotypic Myelodysplastic syndromes: general classification cytogenetics refractory anemia ... MDS unclassified Myelodysplastic/myeloproliferative syndromes: general chronic myelomonocytic leukemia atypical chronic myeloid leukemia juvenile myelomonocytic leukemia ... other pediatric MDS Primary references top American Journal of Clinical Pathology (AJCP) , Jan1997 to Jan2002 American Journal of Surgical Pathology (AJSP) , Aug1979 to Feb 2003 Archives of Pathology and Laboratory Medicine (Archives) , Jan1997 to Jan2002 Human Pathology (Hum Path) , Jan1997 to Dec2001 Modern Pathology (Mod Path) , Jan1988 to Jan2003 Kjeldsberg, CR: Practical Diagnosis of Hematologic Disorders (3rd Edition); ASCP Press, 2000 Please refer to these primary references for more detailed discussions and photographs AML Acute myelogenous leukemia (AML) - general top Neoplastic proliferations of hematopoietic precursor cells, causing excessive myeloblasts and other immature myeloid cells

108. Acute Lymphocytic Leukemia, Basic This acute lymphocytic leukemia (ALL) basic overview covers ALL symptoms, diagnosis and treatment options including blood stem cell transplants. NMDP Home, http://www.marrow.org/MEDICAL/all.html

Home Medical Information Diseases Treatable By Stem Cell Transplant > Acute Lymphocytic Leukemia, basic Acute Lymphocytic Leukemia (ALL), basic Many articles on this Web site are written at two levels: The basic version is written at an introductory level and includes explanations of medical terminology. In the future, an advanced version will contain in-depth information written in the style of a medical journal. Jump to a Section: Symptoms and Diagnosis Chemotherapy Blood Stem Cell Transplant Two Types of Stem Cell Transplants: Autologous and Allogeneic Acute lymphocytic leukemia, also called acute lymphoblastic leukemia and acute lymphoid leukemia, is a common leukemia. About 4,000 new cases are diagnosed each year in the United States. Most cases of acute lymphocytic leukemia (ALL) occur in children under age 10, but it can appear in all age groups. ALL is an acute leukemia, which means it is a disease that gets worse quickly. ALL is not inherited. It is caused by a change in the cells in the bone marrow. In most cases, no one knows why this change occurs, but a few environmental factors are linked with ALL. These include high doses of radiation and exposure to toxins before birth or in early childhood. Symptoms and Diagnosis In a healthy person, the bone marrow makes the blood stem cells that turn into the white blood cells, red blood cells and platelets in the blood. An ALL patient's marrow makes too many blast cells (immature white blood cells). These blast cells should turn into the white blood cells called lymphocytes, but they do not. So many blast cells grow that the marrow does not have room to make the normal red blood cells, white blood cells and platelets. This causes these symptoms of ALL:

109. Acute Myelogenous Leukemia (AML), Basic Acute myelogenous leukemia symptoms, diagnosis and treatment options, including blood stem cell transplants. NMDP Home, Acute Myelogenous leukemia (AML), basic http://www.marrow.org/MEDICAL/aml.html

Home Medical Information Diseases Treatable By Stem Cell Transplant > Acute Myelogenous Leukemia (AML), basic Acute Myelogenous Leukemia (AML), basic Many articles on this Web site are written at two levels: The basic version is written at an introductory level and includes explanations of medical terminology. In the future, an advanced version will contain in-depth information written in the style of a medical journal. Jump to a Section: Acute Myelogenous Leukemia Symptoms and Diagnosis Chemotherapy Blood Stem Cell Transplant Two Types of Stem Cell Transplants: Autologous and Allogeneic Acute myelogenous leukemia (AML) is also known by several other names, including acute myeloblastic leukemia, acute myelocytic leukemia and acute nonlymphocytic leukemia. AML is not inherited or contagious. It develops when there is a defect in the immature cells in the bone marrow. The exact cause of AML is unknown, but some environmental factors are linked with AML, including exposure to radiation and benzene. AML occurs in all ages but more often in older adults. With more than 10,000 new cases diagnosed annually, AML is the more common type of acute leukemia in adults (the other type is acute lymphocytic leukemia Acute Myelogenous Leukemia Symptoms and Diagnosis Acute myelogenous leukemia (AML) symptoms result from the body not producing enough healthy blood cells. Healthy bone marrow makes stem cells that grow into the three types of blood cells: red blood cells, white blood cells and platelets. An AML patient's bone marrow makes too many blast cells (immature white blood cells). Normal blast cells turn into a type of white blood cell called granulocytes, but the leukemia blast cells do not. At the same time, the marrow cannot grow enough normal red blood cells, white blood cells and platelets.

110. CaringBridge.org - Kendrie Little Kendrie is a child who is fighting leukemia. Site includes her story, and pictures. http://www.caringbridge.org/ga/kendrie

about CaringBridge home page view guestbook view photos ... make a tribute donation Welcome to Kendrie's Page! Diagnosed with ALL in October, 2003, one month after her 4th birthday, Kendrie is a happy, giggly little girl who is a tomboy at heart. She loves playing outside, swimming, riding her bike, building forts, and says when she grows up, she wants to be "a boy". On occasion, though, we catch her playing with dolls (usually GI'Joes), so not all hope is lost yet! :) NEW PHOTOS ADDED TO THE PHOTO ALBUM APRIL 14, 2004 FAQ RE ALL (how’s that for short and sweet?) Q. What, exactly, is leukemia? "Well, to be honest, it’s pretty much the biggest suck-fest our family has ever faced. Oh, you wanted the medical definition? Well, in that case, leukemia is cancer of the blood forming tissues that make up the bone marrow inside the large bones. The diseased bone marrow then floods the body with abnormal white cells. These cells do not perform the infection fighting functions of healthy, mature white cells. In addition, production of red cells, which carry oxygen, and platelets, which help prevent bleeding, is decreased. Around our house, in laymen’s terms, leukemia is “sick blood”." Q. Are there different types of leukemia?

111. Childrens Leukemia Research Association! Childrens leukemia Research Association! Describing National leukemia, children s leukemia, National leukemia Association and Team leukemia. http://www.childrensleukemia.org/

childhood leukemia,leukemia, cancer, myeloid leukemia, blood disorders, patient aid, children's leukemia, childhood diseases, children's leukemia research association, hematology, research grants, oncology, team leukemia, countdown to a cure, pediatric hematology, children's blood disorders, childhood blood disorders, diseases, leukemia patient aid program, leukemia research grant, Peter Wiernik, Janice Dutcher, George Marcoullis, marcoulis, wiernick, ducher, our lady of mercy , comprehensive cancer center, sti571, interferon, myelogenous, t cells, t-cells, donations, charitable donations, money goes to research, leukemia, lukemia Click Here for CLRA's "Countdown to a Cure!" Updates and Information... The Children's Leukemia Research Association's "T EAM L EUKEMIA " Medical Advisory Committee of the Children's Leukemia Research Association Janice P. Dutcher, MD Currently Professor of Medicine at New York Medical College and is Associate Director for Clinical Affairs at Our lady of Mercy Comprehensive Cancer Center, Bronx New York Peter H. Wiernik, MD

112. The Mark Forti Leukemia Fund WebSite Includes involvement history and fundraising information. http://www.markfortifund.com/

The Mark Forti Leukemia Fund WebSite Helping Kids With Cancer Leukemia Fund Cancer Kids Mark Forti Click here to enter http://24.60.113.94 namesdirect.com - Register your domain name

113. Curing Childhood Leukemia - Summary reproduce uncontrollably. This article describes the treatment developed for leukemia, a cancer of the blood and bone marrow. In http://www.beyonddiscovery.org/content/view.asp?I=285

114. Leukemia Provides overview of the condition, including definitions, causes, symptoms, diagnosis and treatment. http://www.mamashealth.com/leukemia.asp

Mamashealth.com Home Cancer Pages Anal Cancer Breast Cancer Breast Cancer Treatment Cancer ... Breast Cancer Journey Links Email Mama What is Leukemia? Leukemia is a cancer that starts in the organs that make blood, namely the bone marrow (the soft inner part of the bone) and the lymph system. In leukemia, abnormal and immature white blood cells are produced in the bone marrow and lymph system. The immature white blood cells are called leukocytes. In some individuals, leukocytes are so numerous that the blood actually has a whitish tinge. When abnormal and immature white blood cells are produced, production of normal cells decreases and the ability to fight infection decreases. The ability to fight infection decreases because the leukemic cells accumulate and lessen the production of oxygen-carrying red blood cells, blood-clotting cells (platelets), and normal leukocytes. If left untreated, the surplus leukemic cells overwhelm the bone marrow, enter the bloodstream, and will eventually invade other parts of the body, such as the lymph nodes, spleen liver , and the brain , and spinal cord.

115. Childhood Acute Lymphoblastic Leukemia - Acute Lymphocytic Leukemia In Children Acute Lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood, representing nearly one third of all pediatric http://www.emedicine.com/ped/topic2587.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Oncology Acute Lymphoblastic Leukemia Last Updated: September 15, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: acute lymphocytic leukemia, acute lymphatic leukemia, acute lymphoid leukemia, ALL AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Jeffrey E Rubnitz, MD, PhD , Director of Fellowship Training Program, Associate Professor, Departments of Pediatrics and Hematology-Oncology, University of Tennessee and St Jude Children's Research Hospital Jeffrey E Rubnitz, MD, PhD, is a member of the following medical societies: American Society of Hematology Editor(s): Kathleen Sakamoto, MD , Associate Professor, Departments of Pediatrics and Pathology, University of California at Los Angeles and Mattel Children's Hospital; Robert Konop, PharmD

116. Some Moore Cats - Feline Leukemia Story about a cat called Maxwell and his battle with FeLV and his chronic eye problems, including corneal ulcers, entropion, and conjunctivitis. http://www.somemoorecats.com/felv.shtml

June 10, 2004 Pictures, Games, Stories, Cards, Resources, and Moore! Home Photo Gallery Postcards Shoppe Menu About Us Home Callie Chloe Duncan ... Photo Gallery Just Fur Fun Tell a Friend About Us Duncan's Dining Kitty Poll Cat Concentration ... Photo Contest Seriously... Links and Resources Online Shoppe Feline Leukemia Maxwell's Journal ... View our Guestbook Feline Leukemia (FeLV) - One Cat's Experience Related Information: Read Maxwell's Journal - The Diary of a FeLV+ Cat, started January 20, 2000 on his fifth "purrday". Maxwell was included in an article about Feline Leukemia at VetCentric.com.... the article is reprinted here with permission. Maxwell: [ Page 1 Page 2 Article FeLV Diary Maxwell's Story Maxwell came to me as a tiny babycat of about 10 weeks in April 1995. He had been abandoned out in the country near the home of a friend of mine. He found his way to her front porch, and from there, into my home and heart. (You can read more about Maxwell's early story at the Comeback Kitties page where our Dexter's FeLV Resources There are many excellent resources available on the internet addressing this dreadful and heartbreaking disease so I won't try to duplicate that information here. If you have a FeLV+ cat or are interested in more information about the disease, I would encourage you to check out our

117. EMedicine - Acute Lymphoblastic Leukemia : Article By Karen Seiter, MD Acute Lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a malignant (clonal) disease of the bone marrow in which early lymphoid precursors http://www.emedicine.com/med/topic3146.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Acute Lymphoblastic Leukemia Last Updated: June 4, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: ALL, lymphoid precursor cells, lymphoblasts, malignant lymphoid disorder, cancer, bone marrow malignancy, bone marrow cancer, leukemia, bone marrow failure, lymphoma, bone marrow carcinoma AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Karen Seiter, MD , Associate Professor, Department of Internal Medicine, Division of Oncology/Hematology, New York Medical College Karen Seiter, MD, is a member of the following medical societies: American Association for Advancement of Science American Association for Cancer Research American College of Physicians American Society of Clinical Oncology , and American Society of Hematology Editor(s): Clarence Sarkodee-Adoo, MD

118. CaringBridge.org - Julianna Julianna Banana is a little girl that was diagnosed with acute lymphoblastic leukemia. Site includes her story, and photos of her. http://www.caringbridge.org/canada/julianna

about CaringBridge home page view guestbook view photos ... make a tribute donation Julianna Banana! Hello everyone, welcome to my web page! My name is Julianna and I live in Winnipeg, Canada, home of Winnie the Pooh. I'm 3 years old, brown hair and brown eyes, single and a non-smoker. My turn-ons include pink clothes, Barbie toys and playing. My turn-offs are medicine and when my brother stands in front of the tv. Please stop by from time to time and see what I'm up to :-) On September 4, 2003, the doctors told mom and dad that I have acute lymphoblastic leukemia, standard risk, pre-B cell type and that I'm on the CCG 1991 treatment plan protocol...whatever that means. Oh well, as long as mom figures out my medicine and dad keeps changing the kitty litter, I'll just keep playing barbies. I have to go back to the hospital one or two times a week. The needles are NO fun at all, those ladies who always SEEM so nice always want to hold me down and stick things in my back. They don't know that I'm taking names and it's payback time when I'm not so little, mwahahaha! My Nonna lives in Brandon, Manitoba, but she just moved in! HOW COOL IS THAT?! Not many kids get their grandmas cooking anytime they want!

119. Blacksburg Area Volunteers Against Leukemia Organization promoting public awareness of blood related cancers, aiding area patients and programs and increasing the voluntary bone marrow donor registry. http://baval0.tripod.com/fightleukemia/

var cm_role = "live" var cm_host = "tripod.lycos.com" var cm_taxid = "/memberembedded" Check out the NEW Hotbot Tell me when this page is updated Our Purpose Calendar of Events ... Contact Us Blacksburg Area Volunteers Against Leukemia Welcome to our web site! We are Blacksburg residents fighting Leukemia in our area. We do this by promoting public awareness of Leukemia, blood related cancers and the importance of bone marrow donation. We want to help any patients in any way that we can. We are continuously fundraising to offset the high cost of tissue typing for volunteer bone marrow donors. We will run drives to increase the registry of donors. YOU ARE THE PERSON TO VISIT OUR WEBSITE I have signed up to run my first marathon. Click below to follow me from my zero miles a week to running the event..... My TNT experience We are people who have been touched by blood related cancer. Someone we know has been diagnosed or has succumbed to a blood related cancer. If you have ever known anyone with a life threatening illness, The experience is truly a helpless one. The odds of something that I or anyone else does in the name of a specific person are long that it will help that person. But, whoever it is: college student, child, friend or family member. It will happen to someone just like them tomorrow. There is only one way to prevent that. Please take the time to sign our guest book and let us know who you are: We invite you to visit us or attend an event. Our members are more than happy to answer any questions you may have about the organization and how you can join.

120. Acute Lymphoblastic Leukemia Acute Lymphoblastic leukemia. Infantile leukemia is associated with high tumor burden, high white counts, organomegaly and CNS involvement. http://gucfm.georgetown.edu/welchjj/netscut/heme_onc/all.html

Acute Lymphoblastic Leukemia Introduction FAB classification Biological classification ALL derived from B cells Cell surface markers and B cell differentiation pre-pre-B ALL pre-B ALL B cell ALL ALL derived from T cells ... Treatment Introduction The acute leukemias account for about one third of childhood cancer, and about three quarters of these leukemias are ALL (the others being AML or acute undifferentiated leukemia). In general, ALL has a better outcome than AML. Lymphoblasts can be distinguished from myeloblasts in a number of ways: Characteristic Lymphoblasts Myeloblasts Chromatin smooth, homogenous more fine Nucleoli indistinct punched out Cytoplasm small rim more abundant Granules rare yes sometimes Auer rods PAS positive glycogen globs small, fine PAS staining MPO Negative Most positive Sudan Black Negative Cytoplasmic lipid stains positive FAB Classification of ALL The FAB Classification relies on morphology, dividing blasts into L1, L2 and L3 by their appearance. These categories are not well related to biology or outcome except for the L3 blasts. These are derived from immunophenotypically distinct mature B cells. Small Larger Large Almost no cytoplasm About 20% cytoplasm Basophilic Cytoplasm Cytoplasmic vacuolization Round to cleaved nucleoli Perinuclear chromatin More prominent nucleoli Biological Classification of ALL ALL blasts are derived from either B-cell or T-cell lineages, as determined by cell surface and other markers. A small percentage of the cells are either so primitive that they do not express enough markers to identify, and these comprise the AUL category. As more markers are elucidated, the number of leukemias falling into this wastebasket category is declining. The mixed cell leukemias represent another difficulty for classification: they are not clearly B or T cells and may represent a very early precursor (perhaps of both lines) or lineage infidelity.

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