81. HDA NORTH WEST LANCASHIRE BRANCH The North West Lancashire branch of the Huntington s disease Association. Huntington s Huntington s disease or HD is always fatal. It http://members.aol.com/hdanwlancs/

HUNTINGTON'S DISEASE ASSOCIATION North West Lancashire Branch Dedicated to the Care and Support of Huntington's Families General Information Branch Meetings Local and National Contacts Young Carers ... The whole world owes a debt of gratitude to this community without which the Human Genome Project would not be where it is today! Fact Sheets from the Huntington's Disease Association Fact Sheet 1 All about the Huntington's Disease Association Fact Sheet 2 General Information about Huntington's Disease ... EMail Webmaster - John Griffiths s="na";c="na";j="na";f=""+escape(document.referrer) View My Guestbook Sign My Guestbook [Previous] [Join] ... [Skip Next] This webring is hosted by: HACKERSONS E-Mail: Ringmaster

82. Huntington's Disease Information Huntington s disease Information. Please contact the Information Officer if you are looking for information about Huntington s disease (contact details below). http://glaxocentre.merseyside.org/huntsfacts2.html

Huntington's Disease Information For information about Huntington's Disease please see the following website: UK Huntington's Disease Association: http://www.hda.org.uk More links will be added soon. Please contact the Information Officer if you are looking for information about Huntington's Disease (contact details below). There are Huntington's Disease advice clinics held monthly, on the 1st Tuesday of the month at the Glaxo Centre, Liverpool, UK. Please contact the Glaxo Centre to make an appointment. The Glaxo Neurological Centre is a unique non-medical advice and information centre for people with neurological conditions and their carers For more information about neurological conditions contact the Information Officer by e-mailing mnt@gnc.u-net.com , or phoning 0151 298 2999, or using our textphone 0151 298 3289 Return to the Glaxo Centre's Homepage Last Updated July 2003

83. Simple Sugar Eases Huntington's Disease In Mice: Discovery Provides Taste Of A P Simple sugar eases Huntington s disease in mice. alamy.com. A simple sugar called trehalose helps to relieve the symptoms of Huntington s disease in mice. http://www.nature.com/nsu/040112/040112-16.html

updated at midnight GMT search nature science update advanced search Simple sugar eases Huntington's disease in mice Discovery provides taste of a possible route for human drug development. 19 January 2004 HELEN R. PILCHER Trehalose sugar could ease symptoms of Huntington's. A simple sugar called trehalose helps to relieve the symptoms of Huntington's disease in mice. The discovery may help researchers to design drug treatments for the human condition. Huntington's disease is an inherited illness that causes profound cognitive and movement problems. It affects 1 in 10,000 people. There is currently no cure. Nobuyuki Nukina and colleagues from the RIKEN Brain Science Institute in Saitama, Japan, tested a variety of compounds on a test-tube model of the disease . They discovered that sugar compounds seemed to have a positive effect. They then tested one specific sugar called trehalose on genetically modified mice with Huntington's disease-like symptoms. Left untreated, the mice develop aggregates of a badly folded brain protein, called Huntingtin. The animals become uncoordinated, lose weight and die young - at about 3 months old. But when the animals were allowed to drink a weak solution of trehalose for most of their lives, symptoms improved. Sugar-treated rodents had 40% fewer protein aggregates, lived 10% longer and lost 25% less weight. They were also more co-ordinated - they walked more normally and were less likely to fall off a rotating rod.

84. Huntington Disease Seattle. Huntington disease. HD, Huntington Chorea. Authors Table 1. Molecular Genetic Testing Used in Huntington disease. % of Patients. http://www.geneclinics.org/profiles/huntington/details.html

Huntington Disease [HD, Huntington Chorea] Authors: Brendan Haigh, PhD Mahbubul Huq, MD, PhD, FCCMG Michael R Hayden, MB, ChB, PhD, FRCP(C), FRSC About the Authors Initial Posting: 23 October 1998 Last Revision 25 May 2004 Summary Disease characteristics. Huntington disease (HD) is a progressive disorder of motor, cognitive, and psychiatric disturbances. The mean age of onset is 35 to 44 years and the median survival time is 15 to 18 years after onset. Diagnosis/testing. The diagnosis of HD rests on positive family history , characteristic clinical findings, and the detection of an expansion in the HD gene that is 36 CAG trinucleotide repeats Genetic counseling HD is inherited in an autosomal dominant manner. Offspring of an individual with a mutant allele have a 50% chance of inheriting the disease-causing allele Predictive testing in asymptomatic adults at 50% risk is available, but requires careful thought, including pre-test and post-test genetic counseling , as no treatment exists. Asymptomatic at-risk minor children should not have predictive testing . Although infrequently requested

85. Huntington's Disease Huntington s disease. Based Conclusion. Huntington s disease is a devastating illness that affects every aspect of a person s life. Although http://www.asha.org/public/speech/disorders/Huntington-Disease.htm

@import url( /styles/importmenuP.css ); Skip to: content navigation Our site's pages are optimized for Web browsing software that supports current Web standards, as established by the World Wide Web Consortium (http://www.w3c.org/) . Content is accessible from older or less standards-compliant technologies, but its presentation will not be identical to visitors with standards-compliant software. Read more on our site's changes and accessiblity. My Account Find a Professional Shop Logged in as: Guest Login Search for: ADVANCED SEARCH Home For the Public Speech Language and Swallowing ... Disorders and Diseases Huntington's Disease Based on a brochure developed by Lynn Rhoades, M.S., CCC-SLP for the Huntington's Disease Society of America ( www.hdsa.org ) with financial support of the American Speech-Language-Hearing Association. Why Communication and Swallowing Symptoms Arise As brain cells become depleted in Huntington' s Disease (HD), problems may develop in the following three areas: motor control (movement); cognition (thinking); and behavior. Speech and swallowing problems arise when the centers of motor or cognitive control are affected that cause muscle weakness or discoordination, chorea, and problems with memory, sequencing, new learning ability, reasoning, and problem solving. Typically, speech and language functions are primarily controlled in the left side of the brain and swallowing function is controlled in the brainstem (at the base of the brain). Cognitive function is believed to be controlled in the right side of the brain. HD typically begins in the caudate nucleus and putamen, which are located in the central part of the brain (core), and spreads to these other control centers, causing communication and swallowing problems as the disease progresses. Communication

86. Huntington's Disease HUNTINGTON S disease With these advances, our understanding of the disease continues to improve. What Causes Huntington’s disease? http://www.medceu.com/tests/huntington.htm

HUNTINGTON'S DISEASE Objectives By the end of the course the student will be able to: A. Demonstrate knowledge of the history of Huntington's Disease, its causes and familial nature B. Recognize characteristics of the disease including major effects and rate of progression C. Describe methods of diagnosis, testing, treatment and required care. In 1872, the American physician George Huntington wrote about an illness that he called "an heirloom from generations away back in the dim past." He was not the first to describe the disorder, which has been traced back to the Middle Ages at least. One of its earliest names was chorea, which, as in "choreography," is the Greek word for dance. The term chorea describes how people affected with the disorder writhe, twist, and turn in a constant, uncontrollable dance-like motion. Later, other descriptive names evolved. "Hereditary chorea" emphasizes how the disease is passed from parent to child. "Chronic progressive chorea" stresses how symptoms of the disease worsen over time. Today, physicians commonly use the simple term Huntington's disease (HD) to describe this highly complex disorder that causes untold suffering for thousands of families. In the United States alone, about 30,000 people have HD; estimates of its prevalence are about 1 in every 10,000 persons. At least 150,000 others have a 50 percent risk of developing the disease and thousands more of their relatives live with the possibility that they, too, might develop HD.

87. The Australian Huntington Disease Association (Victoria) The Australian Huntington disease Association promotes the needs and interests of people affected by Huntington disease. Information http://www.ahda.com.au/

Welcome to the Home Page of the Australian Huntington Disease Association (Vic) The AHDA (Vic) promotes the needs and interests of people affected by Huntington Disease. If you are viewing this text it is because your browser does not support frames. Please make use of the menu below to view the Australian Huntington Disease Association (Vic) web site. About the AHDA What is Huntington Disease (HD)? Services Provided by the AHDA (Vic) Other Huntington Disease Specific Services in Victoria ... Contact the Australian Huntington Disease Association (AHDA)

88. Huntington's Disease Drug Works Note You do not have JavaScript enabled. The path from research to effective treatment for Huntington s disease is like a train on a track. http://hddrugworks.org/

17171 Bothell Way PMB 148 Lake Forest Park, WA 98155 1-866-280-3799 or 206-362-0142 home about us statement of purpose how to help clinical studies background ... trial agents THE HUNTINGTON TRAIN TO GLORY Connecting HD people to HD research AC_FL_RunContent("src", "hunt3", "movie", "hunt3", "width", "680", "height", "180"); Note: You do not have JavaScript enabled. T he path from research to effective treatment for Huntington's disease is like a train on a track. Scientists built this train, with support from hard-working Huntington's organizations along with the sweat and tears of many HD families. Borrowing from Woody Guthrie's eloquent lyrics, this Huntington's train is truly bound for glory. The research engine has been fired up with explosive energy as more is learned about the biology of this disease in several model systems. This train has gathered speed as first one, then several drugs and agents have been found which partially treat the disease in mouse models. Scientists believe that drugs which are therapeutic in the mouse have the highest chance of success in people. But therapeutic response is much easier to study in HD mice than in HD people. So despite growing momentum and strong effort, the Huntington's glory train has not yet been able to get over the hill from research to people with even a single recommended treatment. So this is the time and place for Huntington's Disease Drug Works (HDDW) to start its work. We'll bring the tools we already have (available drugs and agents) and put them together with the motivated workforce of HD people. We can traverse the hill between research and therapy for HD. We can do it for this generation.

89. Welcome To The New Jersey Chapter Of The Huntington's Disease Society Of America The New Jersey Chapter of the Huntington s disease Society of America was founded in 1976 to assist affected families and support research to find a cure. http://www.hdsanj.org/

About HD NJ Chapter Chapter Events Family Service Center ... Recruitment for Research on Huntington's Disease The Huntington's Disease Society of America - New Jersey Chapter 114B South Main Street P.O. Box 67A Cranbury, NJ 08512 (609) 448-3521 fax info@hdsanj.org Member of Community Health Charities Visit our Chapter Events Page for More Details The New Jersey Chapter of the Huntington's Disease Society of America was founded in 1976 to assist affected families and support research to find a cure. It is the only voluntary health agency dedicated to serving HD families in the state and sponsors family services, education and research. The Chapter helped found and is affiliated with the Samuel L. Baily Huntington's Disease Family Service Center at the University of Medicine and Dentistry of New Jersey. Services for Huntington's families are provided at three sites across the state. The New Jersey Chapter is part of the national Huntington's Disease Society of America with chapters across the country. The mission statement of the organization is as follows: The Huntington's Disease Society of America (HDSA) is dedicated to finding a cure for Huntington's Disease (HD) while providing support and services for those living with HD and their families. HDSA promotes and supports both clinical and basic HD research, aids families in coping with the multi-faceted problems presented by HD and educates the families, the public and health care professionals about Huntington's Disease. Our HD families give a face to Huntington's Disease; HDSA is its voice.

90. Huntington Disease Huntington disease is going to serve as our prototype for more discussion into the nuances of what we re here for today because http://www.accessexcellence.org/AE/AEPC/BE02/zanko/huns3.html

Huntington Disease is going to serve as our prototype... for more discussion into the nuances of what we're here for today because it is a single gene disorder for which we have DNA prediction of a disease in a healthy individual. You're going to hear me say the prediction word throughout the afternoon because that is the difference. Huntington is a dominantly inherited disorder. It is a disease of brain cells, a loss of neurons, which results in an array of changes. You have a handout that lists many of the changes, looking at the physical changes, the intellectual and the emotional/behavioral. I try to present many things, which unfortunately may change the essence of the person over time. In fact, the physical changes are often the things that the people find the least disturbing. It's the dementia and most of all the behavioral and emotional changes that are so disturbing to my families. The causative gene is at the distal end of the short arm of chromosome 4. It is one of the CAG-trinucleotide repeat mutations. If there are less than 30 repeats, that's OK. 40 or more, absolutely, without question if you live long enough, you will get Huntington. It's not a susceptibility, it's not a percentage, it's an absolute. Again, the

91. Huntington's Disease. Huntington s disease. Aetiology. The gene which predisposes for Huntington s disease is found on Chromosome four, close to the tip of the short arm. http://www.diseasedir.org.uk/genetic/gene0401.htm

Huntington's disease. Disease type: Genetic Disorder Chromosome : Pathology Huntington's disease is thought to arise from the destruction of the GABAERGIC neurons, these neurons use Gamma-amino-butyric acid (GABA) to transfer the electrical impulse from one nerve to the other, GABA is said to be a neurotransmitter Aetiology The gene which predisposes for Huntington's disease is found on Chromosome four, close to the tip of the short arm. The gene is highly polymorphic within the population (ie. there is considerable variance between individuals). The Huntington gene codes for a protein called Huntingtin , whose function is unknown. The gene contains many repeats of the codon (triplet of three DNA bases) C A G. This codon of DNA bases is repeated many times throughout the gene, as much as 20-30 times in normal individuals. In Huntington's patients the CAG repeat is copied up to 50 times. The CAG repeat seems to have significance because there is a statistical link between the number of copies of the CAG repeat and the onset of disease. The more CAG repeats there are the earlier the disease will manifest. Inheritance The gene for Huntington's is dominant, only one copy of the gene is required for the disease. Huntingdon's disease tends to begin around the age of forty, and will result in death around 14 years after the initial onset, the onset of the disease is after reproductive age. The disease has not been removed by

92. Huntington's Disease Is An Inherited Condition. Huntington s disease (HD) is a disease of the brain that affects the nervous system. Huntington s disease is an inherited condition. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Huntington's_dise

93. Huntington's Disease - Dietary Considerations. Huntington s disease (HD) is an inherited disease of the brain that affects the nervous system. Huntington s disease dietary considerations. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Huntington's_dise

94. Huntington's Disease Florida Huntington s disease Sprint and Olympic Distance Triathlon, Sunday, August 1, 2004 Crandon Park (south beach entrance) 4000 Crandon Blvd Key Biscayne, FL, http://www.huntingtonsdiseasefl.org/

Huntington's Disease Sprint and Olympic Distance Triathlon Sunday, August 1, 2004 Crandon Park (south beach entrance) 4000 Crandon Blvd Key Biscayne, FL Online. Act Now! Online Registration Closes July 30, 2004 Host Hotels Eligibility and Rules Training Program Contact Us ... Map to Race Location Course Maps Olympic Distance Map Sprint Distance Map Bike Transition Map The maps were created for Adobe Acrobat. If you do not have Adobe Acrobat Reader you can dowload it from HERE.

95. Type_Document_Title_here A personal website detailing how Huntington's disease has affected Tony's family and friends. http://www.bridger.freeuk.com/

SORRY ! This website can not be viewed by a browser that does Not support Frames! please download an up to date Brower!

96. Testing Positive For Huntington's Disease Testing positive for Huntington s disease is one of the most difficult life challenges that one can face. TESTING POSITIVE FOR HUNTINGTON S disease. http://hdlighthouse.org/diagnosis/testing/updates/0034TestingPositive.phtml

New to the Huntington's Disease Lighthouse: Welcome, start here Beginners Search Diagnosis ... HD Testing Labs Testing Positive For Huntington's Disease HD Lighthouse Editor's Comment: Here is some well expressed good advice from our own Kelly B. Jerry Posted to the HDL: 24 Oct 2003 Testing Positive "It has been six years since I tested gene positive, and I am in the early stages of Huntington's. But I remember like yesterday, the day my world was turned upside down." Kelly B. , HDL Contributing Editor and Chat Rooms Manager. TESTING POSITIVE FOR HUNTINGTON'S DISEASE Testing positive for Huntington's Disease is one of the most difficult life challenges that one can face. I found it to be the equivilant of Alice through the Looking Glass. Everything is upside down and backwards, nothing is normal. It is like your entire world as you have known it to be has changed. There is life before Huntington's and life after finding out you have Huntington's. While things will never be the same as they were before testing positive, and really, how could they. Life will eventually return to running on an even keel after you have had some time to digest your positive result. It is normal to be angry, sad, depressed, and to think that you can not possibly survive the news. But you will, one day at a time, the world will become brighter with time. People ask how long it will take to start to get a grip on it. Each person is unique in how much time it will take them to come to terms with their diagnosis. From people I have spoken to who have gone through it, it seems the average is about six months to one year.

97. Huntington Disease Huntington disease. WHAT IS HUNTINGTON disease? Huntington disease is an inherited, brain disorder that affects both mind and body. http://www.angelfire.com/country/lozon/index1.html

var cm_role = "live" var cm_host = "angelfire.lycos.com" var cm_taxid = "/memberembedded" Huntington Disease WHAT IS HUNTINGTON DISEASE? Huntington Disease is an inherited brain disorder that affects both mind and body. It was named after George Huntington in 1872, the doctor who first described it. It used to be called Huntington's chorea, now it is also know as HD. HD causes cells in specific parts of the brain to die: the caudate, the putamen, and, as the disease progresses, the cerebral cortex. The caudate and the putamen have connections to many other areas of the brain, and help to control body movement, emotions, thinking behaviour, and perception of the world. As the brain cells die, people with Huntington's become less able to control movements, recall recent events, make decisions, and control emotions. The disease leads to incapacitation and, eventually, death. WHO GETS IT? Approximately one in every 10,000 Canadians has HD, with approximately five in every 10,000 at risk of developing the disease. Huntington Disease is a genetic disorder, caused by a faulty gene on chromosome 4. The HD gene is dominant, which means that each child of a parent with HD has a 50% chance of inheriting the disease and is said to be

98. Huntington's Chorea Overview: Huntington s Chorea (Huntington s disease, HD). Huntingtin localization in brains of normal and huntington s disease patients. Ann Neurol 19974260412. http://www.neuro.nwu.edu/meded/MOVEMENT/Huntington.html

Huntington's Chorea (Huntington's Disease, HD) This information is written for Medical Student Education. Please read our Huntington's chorea is a dominantly inherited disease typified by choreoathetosis, rigidity, dementia, ataxia, and ophthalmoplegia.It was first described by George Huntington in 1872. Incidence is 5-10/100,000. Genetically, it is an autosomal dominant disorder with complete penetrance. The mutation, CAG-trinucleotide repeats, may expand in descendent generations explaining anticipation. Onset occurs from childhood (10% of cases) into late life, but is usually in the mid-30s to mid-40’s. Progression is relentless usually ending in death within 10-20 years. The CAG repeats encode glutamines in the gene for "huntington". However the contribution of the mutant form of huntington is presently unclear. Gene imprinting explains the transmission of the childhood form primarily through the father. The disease often presents as "nervousness", and depression. Eventually progresses to include dementia and slowed eye movements. In juvenile HD, rigidity and parkinsonian tremor may be the primary manifestation. HD is a basal ganglia disease; the portions most severely affected are caudate and putamen. The most significant neuropathological change is a preferential loss of medium spiny neurons in the neostriatum. Biochemically there is marked loss of GABA, substance P, enkephalin, angiotension converting enzyme. Neuronal changes begin very early in life, perhaps even from birth. There is no known treatment that will stop progression, but there are symptomatic treatments such as haloperidol. Huntingtons can be diagnosed on MRI by caudate atrophy with appropriate history, and also by genetic testing.

99. Huntington's Disease - Encyclopedia Article About Huntington's Disease. Free Acc encyclopedia article about Huntington s disease. Huntington s disease in Free online English dictionary, thesaurus and encyclopedia. Huntington s disease. http://encyclopedia.thefreedictionary.com/Huntington's disease

Dictionaries: General Computing Medical Legal Encyclopedia Huntington's disease Word: Word Starts with Ends with Definition Huntington's disease or Huntington's chorea is an inherited disorder characterized by abnormal body movements called chorea Chorea "Iliad" This dance form is also known by other ethnoses, under names often derived from the Greek one, e.g., Khorovod in Russia, Hora in Romania, Moldova, and Israel, Horo in Bulgaria. Click the link for more information. , and loss of memory For computer memory, see computer storage. Memory is one of the activities of the human mind, much studied by cognitive psychology. It is the capacity to retain an impression of past experiences. There are multiple types of classifications for memory based on duration, nature and retrieval of perceived items. The main stages in the formation and retrieval of memory, from an information processing perspective, are: Encoding (processing of received information by acquisition) Storage (building a permanent record of received information as a result of consolidation) Retrieval (calling back the stored information and use it in a suitable way to execute a given task) Click the link for more information.

100. Baltimore Huntington's Disease Center Huntington s disease Society of America http//www.hdsa.org. What s Huntington s disease? http//www.personalmd.com/news/huntington_071800.shtml. http://www.hopkinsmedicine.org/bhdc/education/links.cfm

Contents : Home About Huntington's Disease and Related Disorders Faculty Clinical Services ... Contact Us JOHNS HOPKINS Department of Psychiatry Division of Neurobiology Education Helpful Internet Links We have provided these web sites as a resource for you.  We cannot verify the accuracy of all of the information contained at these sites.  Should you have questions regarding information on these sites, please contact your physician for further information. General HD Information Huntington's Disease Society of America http://www.hdsa.org What's Huntington's Disease? http://www.personalmd.com/news/huntington_071800.shtml HDSA Youth http://www.HDSAyouth.com http://www.wemove.org/kidsmove/link.html - or - www.wemove.org Clinical Trial Website for the National Institutes of Health http://clinicaltrials.gov Huntington Study Group http://www.huntington-study-group.org Hereditary Disease Foundation http://www.hdfoundation.org HOPES: Huntington's Outreach Project for Education, at Stanford http://www.stanford.edu/group/hopes

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 5     81-100 of 102    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20