61. Hemophilia Resources Of America (HRA): About Hemophilia Von Willebrand Disease F Information from hemophilia Resources of America. http://www.hrahemo.com/abouthemo/vonwillebrand.html

This information sheet was compiled by Doris Michalovic, RN, MS, FNP Clinical Director, Hemophilia Resources of America Phone (800) 549-2654 Causes Symptoms Who should be tested? Diagnosis ... Resources for additional information What causes von Willebrand disease? Von Willebrand (VWD) is a genetic disorder which can be inherited from either parent. It affects both males and females. VWD is the most common bleeding disorder. It is estimated to occur in approximately one in 100 people and affects all ethnic groups. Over 3,000,000 people in the U.S. are affected. Most people who have this disorder do not know that they have it. What are the symptoms of von Willebrand disease? Symptoms in people with VWD vary from time to time. They may range from none to severe. Typical symptoms include: Frequent or prolonged nosebleeds Easy bruising Heavy or prolonged menstrual periods Prolonged bleeding after injury, surgery, childbirth, or dental work.

62. Bayer Biological Products - USA - Kogenate® FS With added convenience of the 2.5 mL diluent for faster, easier infusions and no albumin in the final formulation, Kogenate ® FS takes hemophilia A treatment http://www.hemophiliabayer.com/

Bayer Global Bayer Corporate - USA Bayer BP - Global general conditions of use ... imprint Kogenate FS Antihemophilic Factor (Recombinant) Formulated with Sucrose Welcome to your online resource for Kogenate FS. It is our goal to provide you with as much helpful information as possible about this treatment option. We strive to provide the bleeding disorders community with the latest in news, associated support programs, and resources. With added convenience of the 2.5 mL diluent for faster, easier infusions and no albumin in the final formulation, Kogenate FS takes hemophilia A treatment to a new level. Today. Building on the ten-year history of Kogenate Antihemophilic Factor (Recombinant) - a history without a single confirmed viral transmission - Kogenate FS offers an extra margin of confidence, made possible through the incorporation of a new sucrose formulation. Developed and manufactured exclusively by Bayer, a company that continues to invest in the advancement of hemophilia treatment.

63. How To Deal With Hemophilia A person with hemophilia, though, has more to worry about than just passing out at the sight of his own blood. What Is hemophilia? http://kidshealth.org/kid/health_problems/blood/hemophilia.html

KidsHealth Kids Kids' Health Problems Blood Does the sight of blood bother you? Some people faint at the sight of blood especially when it's their own. A person with hemophilia, though, has more to worry about than just passing out at the sight of his own blood. What Is Hemophilia? Hemophilia (say: heem-a- fi -lee-ah) is a genetic disorder in which a person's blood does not clot properly. "Hemo" means blood and "philia" means a tendency toward. A person who has hemophilia has a tendency to bleed excessively. Printer -friendly version Email this article to a friend Send email to us Jump to another section of this article How to Deal With Hemophilia A Bit About Blood Why Do Kids Get Hemophilia? How Do Kids Learn They Have Hemophilia? and What Do Doctors Do? ... What Life's Like for Kids With Hemophilia Reviewer name and date on last page About Us Contact Us Partners Editorial Policy Note: All information on KidsHealth is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.

64. THE MERCK MANUAL, Sec. 11, Ch. 131, Hemostasis And Coagulation Disorders Information for doctors from this online textbook. http://www.merck.com/pubs/mmanual/section11/chapter131/131c.htm

This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 11. Hematology And Oncology Chapter 131. Hemostasis And Coagulation Disorders Topics [General] Hemostasis Hereditary Coagulation Disorders Acquired Coagulation Disorders Hereditary Coagulation Disorders HEMOPHILIA Common forms of hereditary bleeding disorders caused by clotting factor deficiencies of factor VIII, IX, or XI. Hemophilia A (factor VIII deficiency), which affects about 80% of hemophiliacs, and hemophilia B (factor IX deficiency) have identical clinical manifestations, screening test abnormalities, and X-linked genetic transmission. Specific factor assays are required to distinguish the two. Genetics Hemophilia may result from gene mutations: point mutations involving a single nucleotide, deletions of all or parts of the gene, and mutations affecting gene regulation. About 50% of cases of severe hemophilia A result from a major inversion of a section of the tip of the long arm of the X chromosome. Because factor VIII and factor IX genes are located on the X chromosome, hemophilia affects males almost exclusively. Daughters of hemophiliacs will be obligatory carriers, but sons will be normal. Each son of a carrier has a 50% chance of being a hemophiliac, and each daughter has a 50% chance of being a carrier. (See also Ch. 286.

65. Hemophilia hemophilia is a rare bleeding disorder that prevents the blood from clotting properly. Read on to learn about hemophilia. What Is hemophilia? http://kidshealth.org/parent/medical/heart/hemophilia.html

KidsHealth Parents Medical Problems Bumps and scrapes are a part of every child's life. For most children, a tumble off a bike or a stray kick in a soccer game means a temporary bruise or a healing scab. But for children with hemophilia, these normal traumas of childhood are reason for extra concern. Hemophilia is a rare bleeding disorder that prevents the blood from clotting properly. Currently, about 17,000 people in the United States have hemophilia. About one in every 8,000 boys is born with hemophilia; girls are more rarely affected by this sex-linked genetic condition. But a male cannot pass the gene for hemophilia to his sons, though all his daughters will be carriers of the disease gene. Every female who carries the gene for hemophilia has about a one in four chance of having a child who has hemophilia. What Is Hemophilia? Human blood contains special proteins, known as clotting factors , that help stop bleeding and allow a blood vessel to heal after an injury. The last step in the clotting process (also called coagulation ) is the creation of a "net" that closes the torn blood vessel and stops the bleeding . This part of the process involves clotting factors VIII and IX. People with hemophilia are deficient in one of those factors due to their disease genes, and as a result, their blood cannot clot properly.

66. MSN Encarta - Hemophilia hemophilia, hereditary blood disease involving the inability of blood to clot, or coagulate, leading to hemorrhage, or bleeding. http://encarta.msn.com/encnet/refpages/RefArticle.aspx?refid=761570021

67. Hemophilia Of Iowa Administrator. This page is hosted by LIGHTHOUSE COMMUNICATIONS, INC. Copyright © 2000, hemophilia of Iowa, Inc. All rights reserved. http://www.hemophiliaofiowa.org/

Hemophilia of Iowa Home What is Hemophilia? Chapter Profile Social Events and Activities ... Other Important Links Welcome!!!!! This page last revised: 05/27/04 07:22 AM Your input is appreciated. Please e-mail your questions or comments to the Web Page Administrator. This page is hosted by LIGHTHOUSE COMMUNICATIONS, INC

68. Choice Source Therapeutics Provide hemophilia care for patients. http://www.choicesource.com

About Us Services Contacts Resources About Us Services Contacts Resources ... Español

69. The Hemophilias: Genetic Disorders Passed From Mother To Son Discusses the heredity caused genetic disorders known collectively as hemophilia, a disease that affects blood clotting. http://www.causes-of-hemophilia.com/

The Hemophilias: Genetic Disorders Passed from Mother to Son Hemophilia is a blood disorder that prevents blood from clotting properly, leading to uncontrolled bleeding. Hemophilia is actually a collection of several different genetic disorders passed on by heredity. The two most common types are hemophilia A and hemophilia B. Hemophilia usually affects males. In fact, one out of every 10,000 males is born with hemophilia A. Approximately 17,000 Americans are born with the genetic disorder that causes the disease. Worldwide, an estimated 500,000 people live with some form of hemophilia. Heredity and Hemophilia The Hemophilias are genetic disorders caused by mutations to a single recessive gene on the X chromosome. Women with these types of genetic disorders rarely develop hemophilia, but can pass the disorders on to their sons. Because hemophilia is an X-linked disease, the hereditary nature of the disease is a complicated issue. Further, a wide variety of genetic disorders cause hemophilia, and many mutations are only found in specific heredity groups. More information on the role heredity plays in hemophilia can be found on this site's Genetics of Hemophilia page.

70. Tonya's Page This page is dedicated to my son, who has hemophilia. http://members.tripod.com/~TKCDAC/index-2.html

This page has moved to http://members.tripod.com/TKCDAC/index.html Please make a note of it. var cm_role = "live" var cm_host = "tripod.lycos.com" var cm_taxid = "/memberembedded"

71. MayoClinic.com - Hemophilia hemophilia occurs when your body lacks one of several clotforming proteins called clotting factors. More Information. hemophilia By Mayo Clinic staff Overview http://www.mayoclinic.com/invoke.cfm?id=DS00218

72. Hemophilia: What Is It? Your Genes, Your Health, DNA Learning Center s multimedia guide to genetic, inherited disorders hemophilia, sexlinked disorder, genetic disorder. http://www.ygyh.org/hemo/whatisit.htm

Concept 1 : Children resemble their parents. Learn how Mendel worked out inheritance in pea plants. Concept 10 : Chromosomes carry genes. Find out how genes are arranged on chromosomes.

73. Haemostasis Forum Dedicated to supplying information on haemophilia to medical and health care professionals, providing an excellent opportunity to interact with worldwide specialists in the field of haematology. http://www.hemophilia-forum.org/

This is a web site dedicated to supplying information on haemophilia to medical and health care professionals, providing an excellent opportunity to interact with worldwide specialists in the field of haematology. Each month the contents of these pages are updated and reviewed by a panel of independent haemophilia specialists. Please click on Faculty Info. This forum is supported by an educational grant from Novo Nordisk A/S. If you would like to access this site, please click on 'Register Now' and submit your details. If you have already registered, please enter your username and password and click on 'accept'. Enter your details here please User name: Password: Cancel Accept Preview this site Register ... Forgot Password

74. Hemophilia Association http://www.hemophiliaz.org/

75. Inheritance Of Hemophilia Xlinked Inheritance hemophilia. Legend hemophilia is a sex linked trait in humans, inherited in the same way white eye color in Drosophila. http://www.accessexcellence.org/AB/GG/x-linked.html

X-linked Inheritance: Hemophilia Legend: Hemophilia is a sex linked trait in humans, inherited in the same way white eye color in Drosophila. Males are hemizygous, receiving their only X chromosome from their mother. Females are heterozygous, inheriting X chromosomes from both parents. If a female has a defective gene on one of her two X chromosomes, she will be protected from its effects by the normal gene on her second X chromosome. If a male has a mutant X and a normal Y chromosome, he will be affected by a X-linked disease. A son, whose mother has two normal alleles, will not be affected by hemophilia even if the father has the disease and the defective gene. A daughter of the same parents will be a heterozygous carrier. A heterozygous carrier mother and a normal father pass the gene for hemophilia on to possibly one- half of their children. Half the daughters will be carriers and half the sons will be hemophilic. The rest of the siblings will be normal. Daughters, as long as one parent is genotypically normal, can only be carriers. The normal gene on the second X chromosome counteracts the defect and the daughters do not suffer from the trait. If a son receives the defective gene from his mother, he will be hemophilic because the Y chromosome can not counteract the defective gene located on his X chromosome. Graphics Gallery Index About Biotech Index Search Home Questions Email This Link

76. Swedish Hemophilia Society Swedish hemophilia Society Swedish hemophilia Society The Swedish hemophilia Society was founded in 1964 and the society is a member of WFH since 1968. http://www.fbis.se/eng.asp

Swedish Hemophilia Society Swedish Hemophilia Society The Swedish Hemophilia Society was founded in 1964 and the society is a member of WFH since 1968. Her Royal Majesty, Queen Silvia, is the Patron of the Society. The Swedish Hemophilia Society is a non-profit nation wide organisation for persons with Hemophilia, von Willebrands Disease and other bleeding disorders. Most members have some form of hemophilia; others are either relatives/family or support members. The goal of the Society is; To retain the interest of persons with hemophilia in the society. To offer guidance and support to its members. To disseminate knowledge about Hemophilia. To strive for the qualified medical care and treatment for persons with hemophilia. In order to obtain better living conditions for persons with hemophilia the Society actively co-operates with other authorities and associations. The Society is a member of the Swedish Disability Movement as well as being a member of international organisations for the care of persons with Hemophilia. An important part of the Society’s work is not only to promote the interests of persons with hemophilia, but also to let others take part of the Society’s knowledge and expertise. This is mostly done by influencing the public opinion in various ways. The Society not only regularly participates in fairs and conferences but also arranges theme-days about Hemophilia. The member magazine “Gensvar” is issued four times a year and is distributed in a large edition. The magazine includes information about hemophilia care, treatment and the work of the Society. The Society also produces several pamphlets about Hemophilia throughout the year.

77. HSC- Hemophilia Society Of Colorado HSC Home Page click here. http://www.cohemo.org/

HSC Home Page - click here HSC Home Page - click here

78. HAVEN HAVEN is an independent organization in Northwestern PA. W Provides patients and their families with information about their condition, treatment options and patient rights. http://members.tripod.com/haven8361/

var TlxPgNm='index'; var cm_role = "live" var cm_host = "tripod.lycos.com" var cm_taxid = "/memberembedded" HAVEN Hemophilia And VonWillebrand's Education Network Mission Vision History Bleeding Disorders Information ... Related Links Welcome to the HAVEN web site. HAVEN evolved from a support group started by the mother of a hemophiliac in Erie, PA in 1997. The support group now includes other affected individuals and families and is gaining the interest and support of the Erie community. The support group organized themselves and identified certain needs within the local Bleeding Disorders Community. HAVEN was created to help address those needs. HAVEN is an independent bleeding disorders association. We seek to provide patients and their families information about their condition, treatment options and patient rights. HAVEN can provide the patients and families with a variety of contacts within the hemophilia community. HAVEN (Hemophilia and von Willebrand’s Education Network) held the 2nd Thank you to the following for their support of the M a r d ... l: Click above for new photos added, 8/27/02

79. Dermatlas: Online Dermatology Image Library Dermatology Image,vascular Malformat Dermatlas Dermatology Images vascular malformation,pseudo-aneurysm,hemophilia,hemoarthrosis,dermatology image images. Match ALL words Match ANY word. http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=-97811613

80. BHPR - Ricky Ray Trust: Blood-Clotting Disorders & HIV - Home Ricky Ray hemophilia Relief Fund Frequently Asked Questions Forms Policies Procedures. Update More than $555 million in compassionate http://bhpr.hrsa.gov/rickyray/

The javascript used on this site for creative design effects is not supported by your browser. Please note that this will not affect access to the content on this web site. Setup Instructions Ricky Ray Hemophilia Relief Fund Frequently Asked Questions Forms Update : More than $555 million in compassionate payments to more than 7,100 eligible individuals and survivors has been committed. All petitions postmarked no later than November 13, 2001 have been processed for payment. No petitions postmarked after November 13, 2001 will be accepted. (5-2-2003) Information about survivors who received less than $100,000 on behalf of an eligible individual (Federal Register, 10-2-2002) History The Ricky Ray Hemophilia Relief Fund was established by the U.S. Congress in 1998 to make compassionate payments of $100,000 to certain individuals with blood clotting disorders, such as hemophilia, who were treated with anti-hemophilc factor between July 1, 1982 and December 31, 1987, and who contracted HIV. Certain spouses and children who contracted HIV from these individuals and specified survivors were also eligible to receive payment. By regulation, petitions filed for payment under the Ricky Ray Hemophilia Relief Fund were required to be postmarked between July 31, 2000 through November 13, 2001.

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