1. Cancer GeneticsWeb - Home Page cancer geneticsWeb www.cancergenetics.org. http://www.cancerindex.org/geneweb/

Cancer Genetics Web www.cancer genetics.org This site includes pages for 606 cancer related genes and entries for chromosome abnormalities. Search: Welcome If you are a first time visitor please read the introduction The site is primarily intended for health professionals and researchers. The aim of the site is to provide comprehensive links to reliable information about genes, their associated proteins, and genetic mutations associated with cancer and related disorders. Each gene page includes links to major genetic databases and where possible links to other related web sites, abstracts references, external searches, and summary information. The site is integrated with Guide to Internet Resources for Cancer to provide links to related clinical and research information sources. Please note: the site includes putative oncogenes / tumour supressor genes and proto-oncogenes implicated in cancer but for which the association with cancer is not necessarily proven. Links to other databases and research abstracts and pre-configured searches of PubMed are included to provide a gateway to available evidence and the latest research relating to specific genes and their role in cancer.

2. Ask NOAH About: Cancer Genetics Ask NOAH About cancer genetics. genetics Basics. Genetic Disorders Basics. cancer genetics Basics. Your Family History. What are cancer Genes? Gene Testing and Counseling. Gene Therapy. Special Considerations. Breast and Ovarian cancer genetics cancer genetics Oncology.com. cancer genetics Overview - National cancer Institute. cancer and http://www.noah-health.org/english/illness/cancer/cancgen.html

Ask NOAH About: Cancer Genetics What are Cancer Genetics? Specific Issues Genetics Basics Genetic Disorders Basics Cancer Genetics Basics Your Family History ... Information Resources What are Cancer Genetics? Genetics Basics Genetic Disorders Basics Cancer Genetics Basics About Cancer Genetics - Oncology.com Cancer Genetics Overview - National Cancer Institute Cancer and Genes - National Center for Biotechnology Information (NCBI) Do You Have Cancer in Your Family? - Pacific Northwest Regional Genetics Group ... PDF File of 2 Pages) Does Cancer Run in Your Family? Understanding Inherited Risk - Canadian Cancer Society (also in French Genetics and Cancer - New South Wales Genetics Program, Australia How Does Cancer Start? - CancerHelpUK Introduction: Genetics - CancerCare ... What Causes Cancer: Risk Factors: Heredity - BC Cancer Agency Your Family History About Family History - CancerCare Family Cancer History Form - Barnes Jewish Hospital Family History Tools - AMA Forecasting Your Future with Genetic Counseling - Barnes Jewish Hospital ... Heredity and Cancer - Virtual Hospital What are Cancer Genes? About Apoptosis - National Institutes of Health Enemies Within - Wellcome Trust Genes and Cancer - Wellcome Trust Genes and Diseases: Harvey Ras Oncogene - NCBI ... How Oncogenes Cause Cancer - North Dakota State University, Phillip McClean

3. National Cancer Institute - Prevention, Genetics, Causes Breast cancer Prevention, genetics, Causes. Cervical cancer Prevention, genetics,Causes. cancer Prevention. cancer genetics. cancer Causes and Risk Factors. http://www.cancer.gov/cancerinfo/prevention-genetics-causes

var bSearchBoxBool=false; Prevention, Genetics, Causes Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Post-Surgery Chemo and Early Lung Cancer Head and Neck Cancer: Cetuximab Boosts Survival President's Panel Report: Living Beyond Cancer Annual Report to the Nation ... Past Highlights Specific Cancers Prevention and/or genetics information is available for the following types of cancer. Breast Cancer: Prevention, Genetics, Causes Cervical Cancer: Prevention, Genetics, Causes Colon and Rectal Cancer: Prevention, Genetics, Causes Endometrial Cancer: Prevention, Genetics, Causes ... Stomach (Gastric) Cancer: Prevention, Genetics, Causes Tobacco Information Information about cigarettes and other tobacco products, quitting smoking, tobacco research, and tobacco statistics. Tobacco and Cancer Home Page General Information Other information that may apply to many types of cancer. Cancer Prevention Cancer Genetics Cancer Causes and Risk Factors Digest Page: Proteomics A collection of material about proteomics, the study of proteins inside cells, and how such study is shedding new light on cancer. Home Text-Only Version Contact Us Policies ... Site Map A Service of the National Cancer Institute

4. The Eukaryotic Cell Cycle And Cancer Basic introduction to the eukaryotic division, and its relationship to oncogenes and tumour suppression, from to genetics of cancer, from North Dakota State University, Fargo. http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/cellcycle/cellcycl1.htm

The Cell Cycle Cell Growth, Cancer and Oncogenes Retroviral Oncogenes Human Oncogenes How Oncogenes Cause Cancer ... Genetic Topics The Cell Cycle The field of developmental genetics investigates the genetic basis of the changes in form that an organism passes through during its life cycle. One cellular process that is common throughout these changes in form is cell division. The two cell division events that need to be controlled are the entry into the S-phase when DNA is replicated, and the entry into the M-phase when mitosis occurs. In this regard, two timing events need to be monitored by the cell. These are: when to initiate replication (S-phase entry) when to begin chromosomal condensations (M-phase entry) Related to these events are four factors that appear to control the entry into the M-phase. The accumulation of a specific cellular mass is a factor for somatic cells. This is called the mass factor Some cells need to obtain a specific growth rate for mitosis to begin. This is called the growth rate factor The time between successive M-phases appears to be controlled by timer or oscillator genes. This is the

5. Carolina Georgia Cancer Genetics Network Center What is the cancer genetics Network (CGN)? What are the questions the CGN is trying to answer history of cancer, registering in the cancer genetics Network (CGN) offers a unique http://cancer.med.unc.edu/cancergenetics

Home Request More Information Provider Referral Form Duke University ... More information about cancer What is the Cancer Genetics Network? The Cancer Genetics Network (CGN) is a national effort funded by the National Cancer Institute. The purpose of the Cancer Genetics Network is to help scientists and health care providers understand the causes of cancer, and to help them detect, prevent and treat cancer. The Network includes eight centers working together to create a registry, or list, of individuals at increased risk for cancer who are willing to learn about and possibly participate in future research projects developed through the Cancer Genetics Network. The Cancer Genetics Network will collect basic medical and family information on each participant. This information will be updated every year and may be useful in answering some basic research questions about cancer and genetics. Back To Top What are the questions the CGN is trying to answer? Scientists will use the CGN to answer questions about cancer and genetics. Examples of questions that researchers may want to study include:

6. Www.cancergenetics.org/ cancer.gov genetics of Breast and Ovarian cancer (PDQ®) Date Last Modified 03/11/2004, genetics of Breast and Ovarian cancer. (Refer tothe PDQ summary cancer genetics Overview for more information on linkage analysis http://www.cancergenetics.org/

7. ThinkQuest : Library : Life: A Study Of Genetics And Molecular Biology Source of information from the basics to contemporary issues such as cloning and cancer. Includes interactive demonstrations and a discussion forum. http://library.thinkquest.org/20465/

Index Life Science Genetics Life: A Study of Genetics and Molecular Biology The science of genetics is a rapidly growing field. From decoding DNA to cloning, from gene splicing to laws of heredity, there is a lot we know and a lot still to learn. Here is a comprehensive guide. From the sections on atoms, molecules, chromosomes, and cells, you'll learn the basics. Then read up on the controversy surrounding cloning. Find out who are the leaders in genetic research, and for fun try the genetics games. Visit Site 1998 ThinkQuest Internet Challenge Languages English Students Andrew Ocean View High School, Huntington Beach, CA, United States Padraig Ocean View High School, Huntington Beach, CA, United States Melissa Medill Bair High School, Fairless Hills, PA, United States Coaches John Rosary High School, Fullerton, CA, United States Jim Ocean View High School, Huntington Beach, CA, United States John N. Medill Bair H.S., Fairless Hills, PA, United States Want to build a ThinkQuest site? The ThinkQuest site above is one of thousands of educational web sites built by students from around the world. Click here to learn how you can build a ThinkQuest site.

8. National Cancer Institute - Cancer Genetics cancer genetics. General cancer genetics Information. Glossary of Genetic Terms.Understanding Gene Testing. cancer genetics Overview (PDQ®). http://www.nci.nih.gov/cancerinfo/prevention-genetics-causes/genetics

var bSearchBoxBool=false; Cancer Genetics Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Post-Surgery Chemo and Early Lung Cancer Head and Neck Cancer: Cetuximab Boosts Survival President's Panel Report: Living Beyond Cancer Annual Report to the Nation ... Past Highlights General Cancer Genetics Information Glossary of Genetic Terms Understanding Gene Testing Find Cancer Genetics Professionals Search: Cancer Genetics Services Directory Specific Cancers Breast Cancer Risk Assessment Tool Questions and Answers About Estimating Cancer Risk in Ashkenazi Jews Genetic Testing for Breast Cancer Risk Genetic Testing for BRCA1 and BRCA2 Policy ASCO Policy Statement on Genetic Testing for Cancer Susceptibility ASHG/ACMG REPORT. Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents Promoting Safe and Effective Genetic Testing in the United States Statement of The American Society of Human Genetics on Genetic Testing for Breast and Ovarian Cancer Predisposition ... Statement on Use of DNA Testing for Presymptomatic Identification of Cancer Risk: Commentary Cancer Genetics Research Resources and Information Cancer Family Registries Cancer Genetics Network Cancer Genome Anatomy Project (CGAP) National Human Genome Research Institute ... Site Map A Service of the National Cancer Institute

9. Cancer Genetics And Developmental Biology [BC Cancer Research Centre] Research focuses on identifying genomic changes, and signaling and metabolic pathways associated with tumour progression. Includes information on research groups, staff, and related resources. http://www.bccrc.ca/cg/

Research Departments People Publications Home ... Departments Cancer Genetics and Developmental Biology Cancer Genetics Cancer Genetics and Developmental Biology Victor Ling - Vice President, Research, BCCA Welcome to the Cancer Genetics and Developmental Biology Home Page. The fundamental concept that cancers progress via accumulation of multiple genetic abnormalities is widely accepted. Loss of genome stability and integrity in the affected cells is a hallmark of the multi-step process of cancer, which progressively leads to uncontrolled cell growth and metastasis. Our Department focuses on identifying genomic changes, and signaling and metabolic pathways associated with tumour progression. Current activities include: Development and application of highly sensitive techniques to identify and track mutations in patient biopsies at the genome-wide level; Identification of novel tumour suppressor genes and oncogenes associated with various cancer; Elucidating the mechanism of signal transduction mediated by the extracellular matrix (ECM) particularly the family of integral plasma membrane receptors called integrin; Investigating the family of energy dependent ATP-binding membrane transport proteins associated with chemotherapy resistance, hormone secretion and programmed cell death.

10. Division Of Cancer Epidemiology And Genetics (DCEG) Home Page Atlas of cancer Mortality. Breast cancer Risk Assessment Tool HER2 Polymorphism Increases Risk of Breast cancer. Formaldehyde Exposure May More from NCI NewsCenter. NCI cancer Bulletin http://www-dceg.ims.nci.nih.gov/

Home Organization Research Publications Search: Organization Division Directory- Alphabetic by Organization Contact Us, Maps Fellowship Information ... NCI Employment Site Publications DCEG Publications Database DCEG Newsletter "Linkage" Annual Research Directory (PDF) Research Research Interests of DCEG Active Clinical Research Studies NCI Faculties Index Data Sharing Policy ... Accessibility =External Link

11. Home Page Information about this Canadian institutional research strategy and database which addresses the genetic susceptibility of cancer. http://www.acgp.ca

Login Username: Password: Login to Access - Questionnaires - New Referals - Counselling aids Alberta Cancer Genetics Program The Alberta Cancer Genetics Program seeks to improve the health and wellbeing of individuals at increased risk for developing cancer. An important strategy for winning the battle against cancer is prevention. A positive family history is among the strongest epidemiological risk factors for common malignancies including breast, ovarian, colorectal and prostate cancers. Many families are very aware of the devastating effects of cancer. Promoting wellness is a top priority of the Alberta Cancer Genetics Program. Identification of healthy young adults with inherited risk for developing cancer provides the best opportunity for prevention and early detection. Terms of Use " prior to using the ACGP website. By using the ACGP website, you are agreeing to be bound by such terms and conditions set form in the " ". If you do not agree with them, please do not use the ACGP website.

12. Whitehead Institute The Whitehead Institute is a nonprofit, independent basic research and teaching institution recognized worldwide for pathfinding programs in cancer and AIDS research, developmental biology, structural biology, infectious disease, and genetics. http://www.wi.mit.edu/

Who We Are Career Opportunities Public Programs Support the Whitehead ... publications EXPRESS: Principal Investigators F A C U L T Y David Bartel Andrew Chess Gerald R. Fink Rudolf Jaenisch Eric S. Lander Susan L. Lindquist Harvey F. Lodish Paul T. Matsudaira Terry L. Orr-Weaver David C. Page Ilaria Rebay David Sabatini Hazel L. Sive Robert A. Weinberg Richard A. Young F E L L O W S Mark Daly Ernest Fraenkel Alan Jasanoff A F F I L I A T E M E M B E R S David Altshuler Dave Gifford Todd Golub Labs by Subject Agrobiology AIDS Angiogenesis Antibiotic Resistance Biocomputing Group Bioengineering Bioinformatics Biomaterials BioMEMS Chips Biotechnology Brain Brain and Spinal Cord Development Cancer Cancer Genetics Catalytic RNA Cell Biology Cell Cycle Cell Cycle Clock Cell Death Cell Division Cell Signaling Cell-Cell Signaling Chaperone Proteins Chemical Genetics Cloning Combinatorial Chemistry Computational Biology Cytoskeleton Data Mining Developmental Biology Diabetes DNA Arrays DNA Methylation DNA Rearrangement DNA Replication Drosophila Drosophila Genetics Expression Cloning Eye Development Frog and Zebrafish Genetics Fungal Infections Gene Expression Gene Mapping Genome Project Genomics HIV Immune System Infection Infectious Diseases Interdisciplinary Science Leukemia Male Infertility Molecular Evolution MRI Nanotechnology Neural Networks Neurobiology NMR Origin of Life Plant Genetics Prions Protein Chemistry Protein Folding Rapamycin Receptors Ribozymes RNA Sensory System Sex Chromosome Evolution Single Neuron Imaging Small Molecule Screening Smell SNPs Statistical Genetics Stem Cells

13. National Cancer Institute - Genetics Of Breast And Ovarian Cancer Refer to the PDQ summary cancer genetics Overview for more information on linkage analysis the PDQ summary on Elements of cancer genetics Risk Assessment and Counseling for more http://www.nci.nih.gov/cancerinfo/pdq/genetics/breast-and-ovarian

var bSearchBoxBool=false; Date Last Modified: Introduction Major Genes Genetic Polymorphisms and Breast Cancer Risk Interventions Psychosocial Issues in Inherited Breast Cancer Syndromes ... Print-friendly Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Post-Surgery Chemo and Early Lung Cancer Head and Neck Cancer: Cetuximab Boosts Survival President's Panel Report: Living Beyond Cancer Annual Report to the Nation ... Past Highlights Introduction General Information Family History as a Risk Factor for Breast Cancer Family History as a Risk Factor for Ovarian Cancer Autosomal Dominant Inheritance of Breast/Ovarian Cancer Predisposition ... Models for Prediction of Breast Cancer Risk General Information Among women, breast cancer is the most commonly diagnosed cancer after nonmelanoma skin cancer, and is the second leading cause of cancer deaths after lung cancer. In 2004, an estimated 217,440 new cases will be diagnosed, and 40,580 deaths from breast cancer will occur.[ ] (Refer to the PDQ summary on Breast Cancer Treatment for more information on breast cancer rates, diagnosis, and management.)

14. National Cancer Institute - Lung Cancer: Prevention, Genetics, Causes Search cancer genetics Services Directory genetics Search Page Directory ofprofessionals who provide services related to cancer genetic risk assessment http://www.cancer.gov/cancerinfo/prevention-genetics-causes/lung

var bSearchBoxBool=false; Lung Cancer: Prevention, Genetics, Causes Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Post-Surgery Chemo and Early Lung Cancer Head and Neck Cancer: Cetuximab Boosts Survival President's Panel Report: Living Beyond Cancer Annual Report to the Nation ... Past Highlights Prevention [ patient ] [ health professional ] Expert-reviewed information summary about factors that may influence the risk of developing lung cancer and about research aimed at the prevention of this disease. [ patient ] [ health professional ] Expert-reviewed information summary about research and guidelines focused on the prevention and cessation of cigarette smoking. Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Trial In order to determine the long-term effects from vitamin supplements in smokers, ATBC researchers followed the participants for an additional eight years after the trial ended. Questions and Answers About Beta Carotene Chemoprevention Trials A fact sheet about three clinical trials designed to study whether beta carotene and other agents can prevent cancer. Nutrient in Cruciferous Vegetables Protects Against Lung Cancer in Study NIH News Release Tobacco and Cancer Home Page Information about cigarettes and other tobacco products, quitting smoking, tobacco research, and tobacco statistics.

15. Division Of Cancer Epidemiology And Genetics (DCEG)Human Genetics Program: Offic Established in 1996 to provide an expanded focus for interdisciplinary research into the genetic determinants of human cancer. http://www-dceg.ims.nci.nih.gov/hgp.html

Home Organization Research Publications Search: Overview, Programs Human Genetics Program Office of the Director, HGP Joseph F. Fraumeni Jr ., Acting Director Program Staff Directory Branches in HGP Clinical Genetics Genetic Epidemiology Overview and Operating Philosophy The Human Genetics Program was established in 1996 to provide an expanded focus for interdisciplinary research into the genetic determinants of human cancer. Advances in molecular genetics and related biomedical sciences provide extraordinary opportunities both to explore and identify heritable factors that predispose to cancer as well as to elucidate gene-environment interactions. Program investigators conduct family-based and population-based studies that integrate clinical, epidemiologic, and laboratory approaches to investigate genetic susceptibility to cancer. The Program is organized into the Clinical Genetics Branch and the Genetic Epidemiology Branch. Home Contact Privacy Notice Accessibility =External Link

16. National Cancer Institute - Cancer Genetics Overview cancer genetics Overview (PDQ®) Date Last Modified 12/18/2003. cancer genetics Overview. Significance of the Terms Mutation and Carrier. Assumptions Concerning the Identification of People With an http://www.nci.nih.gov/cancerinfo/pdq/genetics/overview

var bSearchBoxBool=false; Date Last Modified: Cancer Genetics Overview Changes to This Summary (12/18/2003) More Information Print-friendly Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Post-Surgery Chemo and Early Lung Cancer Head and Neck Cancer: Cetuximab Boosts Survival President's Panel Report: Living Beyond Cancer Annual Report to the Nation ... Past Highlights Cancer Genetics Overview Significance of the Terms Mutation and Carrier Assumptions Concerning the Identification of People With an Increased Susceptibility to Cancer Evaluation of Evidence Evidence Related to the Clinical Value of Genetic Tests and Family History Information ... Evidence Related to Cancer Prevention Knowledge about cancer genetics is rapidly expanding, with implications for all aspects of cancer management, including prevention, screening, and treatment. PDQ cancer genetics summaries provide information on the genetics of specific cancers, inherited cancer syndromes, and the ethical, legal, social, and psychological implications of cancer genetics knowledge. Sections on the genetics of specific cancers include information on the prevalence and characteristics of cancer-predisposing mutations , the risk implications of a family history of cancer, known modifiers of genetic risk, opportunities for genetic testing, outcomes of genetic counseling and testing, and interventions available for people with increased cancer risk resulting from an inherited predisposition.

17. Cancer And Genetics national and international cancer support groups, genetic resources,genetic clinics with genetic counselors and geneticists. http://www.kumc.edu/gec/support/cancer.html

18. Human Cancer Genetics The Division of Human cancer genetics at The Ohio State University. Located on the College of Medicine campus in Columbus, the overall mission of the Division is the rapid identification, analysis http://www.cancergenetics.med.ohio-state.edu/

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19. Cancer Center Home Provides information about prevention, diagnosis, support, community outreach, genetics, nutrition, research, clinical trials and news, as well as an introduction to the institution. Located in Charlottesville, Virginia. http://www.healthsystem.virginia.edu/internet/cancer/

The Cancer Center Health Care Professionals About Us Site Index Search this site: For Professionals For Patients For Researchers About Us ... The Cancer Center UVa Health System PO Box 800334 Charlottesville , VA 22908 fax: 434-982-0918 For comments and suggestions about this page: webmaster Last Modified: 02/09/2004 of the University of Virginia About This Site

20. CGAP Collaboration Information about NCBI's involvement in NCI's CGAP collaboration. Collaborating on. public cancer data. PubMed. Entrez. BLAST of Nature genetics, entitled "A genomewide map of chromosomal breakpoints in human cancer", is continuously updated http://www.ncbi.nlm.nih.gov/ncicgap

Collaborating on public cancer data PubMed Entrez BLAST OMIM ... Structure Search PubMed GenBank Genomes LocusLink OMIM Proteins Structures for NCBI Projects with CGAP Data Clone Registry dbEST Entrez ProbeSet Gene Expression Omnibus ... UniSTS Cancer Genome Anatomy Project The Cancer Genome Anatomy Project (CGAP) is an interdisciplinary program established and administered by the National Cancer Institute ( NCI ) to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell. From CGAP's inception in 1996, NCBI been a key participant in bioinformatics planning, data tracking, data archiving, and analytical tool development and implementation. NCBI's role in CGAP has been constantly evolving to meet the demands of changing and expanding raw data sources, as well as the needs of the scientific community. The information below highlights NCBI's contributions to CGAP. "characterizing genes" NCBI collaborates closely with NCI as the CGAP pipeline generates large numbers of expressed sequence tags (EST), all of which are deposited into dbEST , and subsequently incorporated into UniGene and HomoloGene . Gene-based, manual annotations may also be added via an interface to

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