81. Health Topics Idiopathic aplastic anemia. Definition Idiopathic aplastic anemia is a failure ofthe bone marrow to properly form all types of blood cells. Alternative Names http://www.netwellness.org/ency/article/000554.htm

How to Use the Information Search Ask an Expert ... Prevention Idiopathic aplastic anemia Definition: Idiopathic aplastic anemia is a failure of the bone marrow to properly form all types of blood cells. Alternative Names: Anemia - idiopathic aplastic Causes, incidence, and risk factors: Idiopathic aplastic anemia is a condition that results from injury to the stem cell, a cell that gives rise to other cell types after it divides. Consequently, there is a reduction in all cell types red blood cells, white blood cells and platelets with this type of anemia , which is called pancytopenia. The cause of idiopathic aplastic anemia is unknown, but is thought to be an autoimmune process (the body reacting against its own cells). Causes of other types of aplastic anemia may be chemotherapy radiation therapy toxins , drugs, pregnancy, congenital disorder, or systemic lupus erythematosus Symptoms arise as the consequence of bone marrow failure. Llow red blood cell count (anemia) leads to fatigue and weakness. Low white blood cell count (leukopenia) causes an increased risk of infection. Low platelet count ( thrombocytopenia ) results in bleeding, especially of mucus membranes and skin.

82. Health Topics Secondary aplastic anemia. Definition Secondary aplastic anemia is a failure ofthe bone marrow to form enough blood cells. All blood cell types are affected. http://www.netwellness.org/ency/article/000529.htm

How to Use the Information Search Ask an Expert ... Prevention Secondary aplastic anemia Definition: Secondary aplastic anemia is a failure of the bone marrow to form enough blood cells. All blood cell types are affected. Alternative Names: Anemia - secondary aplastic; Acquired aplastic anemia Causes, incidence, and risk factors: Secondary aplastic anemia results from injury to stem cells. Normal stem cells divide and differentiate into all blood cell types. Thus, when stem cells are injured, there is a reduction in red blood cells, white blood cells, and platelets. This condition can be caused by chemotherapy, drug therapy to suppress the immune system, radiation therapy, toxins such as benzene or arsenic, drugs, pregnancy, and congenital disorders. When the cause is unknown, it is then referred to as idiopathic aplastic anemia The disease may be acute or chronic and is usually gets worse unless the cause is removed. Review Date: 5/6/2003 Reviewed By: Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network. We'd like to hear from you!

83. Aplastic Anemia Detailed information on aplastic anemia, including cause, symptom, diagnosis,and treatment. aplastic anemia. What is aplastic anemia? http://www.healthsystem.virginia.edu/uvahealth/peds_hematology/aplsanem.cfm

@import url(/assets/UVAHealth/ssi/css/greystone_advance.css); Adolescent Medicine Allergy/Asthma/Immunology Blood Disorders Burns Cancer Common Injuries/Poison Tips Craniofacial Anomalies Dermatology Diabetes/Endo/Metabolism Eye Care Genitourinary/Kidney High-Risk Newborn High-Risk Pregnancy Infectious Diseases Medical Genetics Mental Health Nervous System Disorders Normal Newborns Oral Health Orthopaedics Pediatric Surgery Respiratory Disorders Terminal Illness in Children Transplantation FIND A DOCTOR MAKE AN APPOINTMENT CALENDAR OF EVENTS CLINICAL TRIALS Aplastic Anemia What is aplastic anemia? Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: red cells, white cells, and platelets. A reduced number of red blood cells causes the hemoglobin (a type of protein in the red blood cells that carries oxygen to the tissues of the body) to drop. A reduced number of white blood cells causes the patient to be susceptible to infection. A reduced number of platelets can cause the blood not to clot as easily. What causes aplastic anemia?

84. HealthlinkUSA Aplastic Anemia Links FindWhat. You can find aplastic anemia right now at Info.com. Click here forpage 1 of aplastic anemia information from the HealthlinkUSA directory. http://www.healthlinkusa.com/23ent.htm

85. THE MERCK MANUAL, Sec. 11, Ch. 127, Anemias aplastic anemia (Hypoplastic Anemia). The term aplastic anemia commonly implies apanhypoplasia of the marrow with associated leukopenia and thrombocytopenia. http://www.merck.com/mrkshared/mmanual/section11/chapter127/127c.jsp

86. THE MERCK MANUALSECOND HOME EDITION, Aplastic Anemia When The information. Section 14. Blood Disorders. Chapter 172. Anemia. TopicsIntroduction Anemia From Excessive Bleeding Iron Deficiency http://www.merck.com/mrkshared/mmanual_home2/sb/sb172_1.jsp

87. Aplastic Anemia,Aregenerative Anemia,Erythroblastophthisis,Hemorrhagica Aleukia, aplastic anemia,Aregenerative Anemia,Erythroblastophthisis,Hemorrhagica Aleukia,HypoplasticAnemia,Panmyelopathy,Panmyelophthisis,Progressive Hypoerythemia http://www.icomm.ca/geneinfo/aplast.htm

Aplastic Anemia,Aregenerative Anemia,Erythroblastophthisis,Hemorrhagica Aleukia,Hypoplastic Anemia,Panmyelopathy,Panmyelophthisis,Progressive Hypoerythemia,Refractory Anemia,Toxic Paralytic Anemia,Myelodysplastic syndromes,MDS,Paroxysmal nocturnal hemoglobinuria,PNH,aa For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY Aplastic Anemia also known as: Aregenerative Anemia Erythroblastophthisis Hemorrhagica Aleukia Hypoplastic Anemia Panmyelopathy Panmyelophthisis Progressive Hypoerythemia Refractory Anemia Toxic Paralytic Anemia Disorder Subdivisions Myelodysplastic Syndromes (MDS) Paroxysmal nocturnal hemoglobinuria (PNH) (as defined by the National Organization for Rare Disorders Aplastic Anemia is a rare bone marrow disorder characterized by decreased function of the bone marrow that results in abnormally low levels of all the cellular elements of the blood (pancytopenia). In some cases, the disorder may affect primarily single cell lines (i.e., red blood cells, white cells, or platelets).

88. Aplastic Anemia aplastic anemia. aplastic anemia is a rare but very serious conditionin which the patient s bone marrow stops producing red blood cells. http://www.drhull.com/EncyMaster/A/aplastic_anemia.html

Help for sleepless parents Encyclopedia Index A aplastic anemia Search aplastic anemia red blood cells bone marrow transplantation. In pancytopenia, a related condition of bone marrow stem-cell failure, all cell lines are affected, including red and white cells as well as platelets.

89. Aplastic Anemia First Previous Next Last Index Home Text. Slide 49 of 57. http://www.vet.purdue.edu/vpb/clinpath/vpb555/555rbc3/sld049.htm

90. Aplastic Anemia - Duke Comprehensive Cancer Center aplastic anemia aplastic anemia is a rare but extremely serious disorder that resultsfrom the unexplained failure of the bone marrow to produce blood cells. http://cancer.duke.edu/aplastic_anemia/

Aplastic Anemia Aplastic anemia is a rare but extremely serious disorder that results from the unexplained failure of the bone marrow to produce blood cells. By contacting the Aplastic Anemia Foundation of America, you can be connected with others in your same situation and receive information free of charge. There are AAFA chapters around the country. To learn more about aplastic anemia treatment and research at Duke Comprehensive Cancer Center, please contact the Duke Consultation and Referral Center at 1-888-ASK-DUKE (275-3853). home contact site map search ... webmaster@canctr.mc.duke.edu Designated by the National Cancer Institute

91. Children's Hospital Of NewYork-Presbyterian aplastic anemia. What it is. aplastic anemia occurs when the bone marrow producestoo few of all types of blood cells red cells, white cells, and platelets. http://wo-pub2.med.cornell.edu/cgi-bin/WebObjects/PublicPediatrics.woa/1/wa/view

92. APLASTIC ANEMIA - Meaning And Definition Of The Word Search Dictionary aplastic anemia Dictionary Entry and Meaning.Pronunciation ey plastik u neemeeu. Medical Dictionary. Definition http://www.hyperdictionary.com/medical/aplastic anemia

English Dictionary Computer Dictionary Thesaurus Dream Dictionary ... Medical Dictionary Search Dictionary: APLASTIC ANEMIA: Dictionary Entry and Meaning Pronunciation: ey'plastik u'neemeeu Medical Dictionary Definition: A condition in which the bone marrow is unable to produce blood cells. HOME ABOUT HYPERDICTIONARY

93. APLASTIC ANEMIA - Meaning And Definition Of The Word aplastic anemia Dictionary Entry and Meaning. Pronunciation ey plastik u neemeeu. Synonymsaplastic anaemia. See Also anaemia, anemia. Medical Dictionary. http://www.hyperdictionary.com/dictionary/aplastic anemia

English Dictionary Computer Dictionary Thesaurus Dream Dictionary ... Medical Dictionary Search Dictionary: APLASTIC ANEMIA: Dictionary Entry and Meaning Pronunciation: ey'plastik u'neemeeu Medical Dictionary Definition: A condition in which the bone marrow is unable to produce blood cells. HOME ABOUT HYPERDICTIONARY

94. CancerWise - Vitamin A Compound Reduces Activity Of Cancer-associated Enzyme In Patient Fights aplastic anemia New Clinical Trial Begins Patient Recruitment inJanuary. Mary Nell Thompson had never heard of aplastic anemia four years ago. http://www.cancerwise.org/december_2003/

Search Protein Now Found Key to Cancer Cell Growth Discovery Could Lead to Drug That Inhibits Cancer ... Go to the Article Study Finds Stem Cells Can Restore Heart Muscle Possible Benefit for Cancer Patients With Heart Failure ... Go to the Article NCI Awards $42 Million to Cancer Prevention Six Centers to Conduct Preventive Clinical Trials ... Go to the Article NCI Recruits Patients, Caregivers, Physicians Study Participants Asked to Give Input on Health Materials ... Go to the Article Printer-friendly y Current Articles Patient Fights Aplastic Anemia New Clinical Trial Begins Patient Recruitment in January Mary Nell Thompson had never heard of aplastic anemia four years ago. Then she was diagnosed with the rare blood disease and soon found herself embarking on a long, tedious journey to maintain her health. Although her improvement has been slow and has had setbacks, it has progressed enough to encourage doctors who have been searching for better treatments for the disease. Her progress is attributed to the drug Neumega® (Oprelvekin), which Thompson, now 63, began taking when she joined an M. D. Anderson clinical trial in 2000. The trial was one of two pilot studies designed for patients with bone marrow failure diseases, including aplastic anemia. Because the drug is FDA approved and has seen some success, as in Thompson’s case, Neumega will be studied again at M. D. Anderson in a new Phase II clinical trial, which begins patient recruitment in January. This time the drug will be used only for aplastic anemia patients.

95. CancerWise - Vitamin A Compound Reduces Activity Of Cancer-associated Enzyme In Patient Fights aplastic anemia New Clinical Trial Begins Patient Recruitment inJanuary. Mary Nell Thompson had never heard of aplastic anemia four years ago. http://www.cancerwise.org/december_2003/print.cfm

Patient Fights Aplastic Anemia New Clinical Trial Begins Patient Recruitment in January Mary Nell Thompson had never heard of aplastic anemia four years ago. Then she was diagnosed with the rare blood disease and soon found herself embarking on a long, tedious journey to maintain her health. Although her improvement has been slow and has had setbacks, it has progressed enough to encourage doctors who have been searching for better treatments for the disease. Her progress is attributed to the drug Neumega® (Oprelvekin), which Thompson, now 63, began taking when she joined an M. D. Anderson clinical trial in 2000. The trial was one of two pilot studies designed for patients with bone marrow failure diseases, including aplastic anemia. Because the drug is FDA approved and has seen some success, as in Thompson’s case, Neumega will be studied again at M. D. Anderson in a new Phase II clinical trial, which begins patient recruitment in January. This time the drug will be used only for aplastic anemia patients. Aplastic anemia is a very rare blood disease in which the bone marrow stops producing enough blood cells, which includes red and white blood cells and platelets. In Thompson’s case her platelets were especially low. Platelets help the body control bleeding by clotting blood. Without it over time, a patient could begin to lose blood (bleeding from the rectum, coughing blood, nose bleeds) and eventually die.

96. Aplastic Anemia aplastic anemia and Lindane 5.3.9.7 Carcinogenicity TARGET ANALYTES.aplastic anemia Toxin Exposure. By Lyle L. Sensenbernner, MD In http://www.headlice.org/lindane/health/toxicology/aplastic_anemia.htm

Lindane Education And Research Network Select a Destination Homepage Animals Lindane Ban Cancer Chemistry Children Environment Health Effects Lindane Index Manufacturers Metabolism Products Product Recalls Superfund Toxicology Women HeadLice.Org Home Discussion Communications Links ... Back Aplastic Anemia and Lindane Carcinogenicity Lindane has been classified as Group B2/C (probable/possible human carcinogen) (U.S. EPA, 1999c) and a cancer potency of 1.3 per mg/kg-d has been listed (HEAST, 1997). Lindane's related isomers, alpha and beta hexachlorocyclohexane, are classified as probable human carcinogens and have cancer potencies similar to that of lindane . In addition to tumors identified in experimental animals, human study data indicate that this chemical may cause aplastic anemia (U.S. EPA, 1993a). TOXICOLOGICAL PROFILE SUMMARIES FOR TARGET ANALYTES Aplastic Anemia Toxin Exposure By Lyle L. Sensenbernner, M.D. In many cases, aplastic anemia has been clearly linked to exposure to certain toxins, although in many cases it is unlikely that a specific case can be identified. Overall there are certain groups of substances which have been clearly shown to be causative agents for aplastic anemia. These include: Toxic chemicals;

97. ACS :: Learn About Aplastic Anemia Learn more. Learn About Cancer aplastic anemia. Learn about aplastic anemia,risk factors, prevention, treatment, and more. All About aplastic anemia. http://www.cancer.org/docroot/LRN/LRN_0.asp?dt=77

98. Thomas Jefferson University Hospital - Aplastic Anemia aplastic anemia What is anemia? Anemia is Always consult your physicianfor a diagnosis. What is aplastic anemia? aplastic anemia http://www.jeffersonhospital.org/e3front.dll?durki=5376&site=585&return=5368

99. Chronic Illness, Children, Aplastic Anemia, Laura Well in March of 1995, I found out that I have this disease called aplastic anemia. Theythink that they might catch aplastic anemia just by being near me. http://www.faculty.fairfield.edu/fleitas/laura.html

100. Educational Needs Of The Child With Aplastic Anemia - Association Of Pediatric O Educational Needs of the Child with aplastic anemia Joan M. O’Brien,BSN RN CPON. aplastic anemia is a rare but complicated illness. http://www.apon.org/i4a/pages/index.cfm?pageid=297

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