1. FDA Approves Enbrel To Treat Ankylosing Spondylitis FDA Approves Enbrel to Treat ankylosing spondylitis, autoimmune News, from bestselling author and patient advocate Mary Shomon of patients with active ankylosing spondylitis (AS), a chronic inflammatory disease other treatments for autoimmune diseases like ankylosing spondylitis, read Mary Shomon's http://www.thyroid-info.com/autoimmune/enbrelas.htm

The Autoimmune Report, the FREE Monthly News Report, Enter your email address here for a free subscription Or Click Here to Send a "Subscribe" Email Autoimmune News: Index MARY SHOMON'S AUTOIMMUNE NEWS SEPTEMBER 2003 Iherb.com SALE price of $8.00 Order now! SUBSCRIBE TO FREE AUTOIMMUNE NEWSLETTER Or send a "Subscribe Autoimmune" email to news@thyroid-info.com Author: Mary J. Shomon ISBN number: List price: $14.95 (US dollars), $8 at Iherb.com Published by: HarperCollins, HarperResource Buy the Book: At local bookstores everywhere ORDER NOW Phone Orders: Call Iherb.com toll-free at 888-792-0028 Online: Iherb.com Contact Mary Shomon, Author, Editor Visit Mary Shomon's Thyroid-Info.com site for thyroid information If you have a suspected or diagnosed thyroid problem, order Living Well With Hypothyroidism , the bestseller in its 17th printing FDA Approves Enbrel to Treat Ankylosing Spondylitis ( September 2003 July 2003 In July, the FDA approved an application for etanercept (trade-name Enbrel), a genetically engineered protein, for a new indication for treatment of patients with active ankylosing spondylitis (AS), a chronic inflammatory disease affecting primarily the lower back and joints. The product is manufactured by Immunex Corporation, Thousand Oaks, Calif. and marketed by Amgen and Wyeth Pharmaceuticals. Etanercept is also licensed for treatment of patients with rheumatoid arthritis, juvenile rheumatoid arthritis, and psoriatic arthritis. Approximately 350,000 patients in the United States have AS. The disease affects men more often than women. Symptoms of the disease may start in adolescence and are usually present by age 30. Patients often have lower back pain and stiffness, chest pain, joint pain and swelling, and tenderness due to the inflammation. In some patients the disease can cause significant pain and disability for many years.

2. ANKYLOSING SPONDYLITIS Most doctors think that ankylosing spondylitis is an autoimmune disease in which a person s immunity is so stupid that it attacks and destroys the joints in http://www.drmirkin.com/joints/J103.htm

ANKYLOSING SPONDYLITIS (REACTIVE ARTHRITIS OF THE SPINE) Gabe Mirkin, M.D. If your back is stiff and hurts when you move, if it hurts to touch two points at the side of the top of your pelvis where it joins your spine (the sacroiliac joint), and if your back x ray shows signs of this disease, you probably suffer from ankylosing spondylitis. You may also have pain and swelling in your eyes, lungs, and heart valves. Most doctors think that ankylosing spondylitis is an autoimmune disease in which a person's immunity is so stupid that it attacks and destroys the joints in his back, rather than just doing its job of protecting a person from infection. They treat you with immune suppressants that may make you feel better, but increase your risk for infections and cancers and shorten your life. Nobody really knows why you have this condition, but the overwhelming evidence is that you inherited your susceptibility from your parents and you got this condition from an infection. When you are infected, your body protects you by making proteins called antibodies and cells called white blood cells that attack and kill the bacteria. Your immunity recognizes each specific germ by the structure of its surface membranes. Ninety percent of people with ankylosing spondylitis have a gene called HLA-B27, which means that their cells have surface membranes that are like the surface membranes on many bacteria, particularly those that grow and live in your intestinal tract. So, if certain bacteria get into your bloodstream, your immunity recognizes these germs by their surface membranes and makes antibodies and cells that attack and kill them. However, if the cells in your body have similar surface membranes, your own immunity can be fooled and think that you are the invading germ and attack and kill your own cells.

3. Ankylosing Spondylitis ankylosing spondylitis ankylosing spondylitis is a chronic, progressive autoimmune disease characterized by arthritis, inflammation, and eventual immobility of a number of joints. ankylosing spondylitis may also be referred to as Strümpell-Marie (or Marie-Strümpell http://www.medical-library.net/sites/_ankylosing_spondylitis.html

Ankylosing Spondylitis ( a.k.a. Strümpell-Marie Disease, Marie-Strümpell Disease, Bekhterev- Strümpell Syndrome, Spondyloarthritis ) by Ron Kennedy, M.D., Santa Rosa, California Ankylosing spondylitis may also be referred to as Strümpell-Marie (or Marie-Strümpell) disease, Bekhterev-Strümpell syndrome, and spondyloarthritis. It is a chronic, progressive autoimmune disease characterized by arthritis, inflammation, and eventual immobility of a number of joints. The disease usually involves the spine and surrounding spinal structures and usually begins between the ages of fifteen and thirty-five years and affects young white males three times as frequently as females. Symptoms of the disease are generally milder among females. This disorder is seen rarely in people of color. Conventional treatment involves the use of Prednisone and other corticosteroids. Often patients are unable to tolerate the toxic side effects of these drugs. The alternative, nutritional medicine approach is to identify hidden allergies by blood test and avoid those allergens (primarily foods). Also enzyme potentiated desensitization holds hope for putting the disease in long term remission.

4. Ankylosing Spondylitis ankylosing spondylitis. ankylosing spondylitis Background. Arthritis Drugs Guidelines ankylosing spondylitis (AS) Background. AS is an autoimmune disease which affects collagen http://www.healingwithnutrition.com/adisease/arthritis/ankylosingspondylitis.htm

HealingWithNutrition.com Home SiteMap Education Products Ankylosing Spondylitis Ankylosing Spondylitis Background Arthritis Drugs Guidelines Cortisone, Prednisone, Hydrocortisone Methotrexate , Showing Nutrients Depleted, Brand Names, Usage, Warnings/Precautions, Adverse Reactions, Overdose Symptoms] Treatment Options AS-Kit Sources: Research References/Bibliography Knowledge gives a person many options for managing ankylosing spondylitis and they can then personally take charge of the effect this disease is having on their life. Return to Main Arthritis Page Ankylosing Spondylitis (AS) Background AS is an autoimmune disease which affects collagen structures, specifically the joints between the vertebrae of the spine. In most cases the cause remains unknown. The commonality of symptoms and cause makes for a close association between AS and rheumatoid arthritis (RA). [The American Medical Association Encyclopedia of Medicine, 1989, p. 111-112] More than 400,000 Americans suffer from AS, and it is most commonly seen in young men between 16 and 35 years of age, and afflicts approximately 1 in 1,000 people under the age of 40. Three times as many males as females are diagnosed with the disease, but this may be because females tend to have much milder symptoms and may never be diagnosed. It also appears in children (mostly boys), who account for roughly 5 percent of the cases. It is rarely seen in African-Americans. A genetic marker or tissue type (HLA-B27) is found much more often in people with AS than in the rest of the population; but 80% of the individuals with this genetic marker never develop the disease. It's not enough to have the genetic tendency; usually there is some event that somehow "switches on" AS, currently studies are looking into the possibility that a certain type of infection triggers AS onset.

5. Hardin MD : Ankylosing Spondylitis From the University of Iowa, the *best* lists of Internet sources in ankylosing spondylitis. Arthritis Pictures. autoimmune Diseases + Pictures spondilitis, ankalosing spondylitis, ankylosis spondylitis, ankylosing spondylitis symptoms, ankylosing spondylitis http://www.lib.uiowa.edu/hardin/md/spondylitis.html

Ankylosing Spondylitis "We list the best sites that list the sites" Site Map Diseases Home Free Articles in PubMed Search Hardin MD See also: Home Arthritis All links on this page hand-checked Popular Women's Health Dermatology Nursing Pharm Infect Disease Arthritis Pictures Autoimmune Diseases +Pictures Back Pain +Pictures Chlamydia Pictures Chronic Fatigue +Pictures Crohns Disease +Pictures Eye Uveitis +Pictures Foot Problems Pictures Heart Pictures ... Osteoporosis +Pictures Psoriasis +Pictures Reiters Syndrome +Pictures Skin Pictures Temporomandibular Joint +Pictures Urinary Infections +Pictures Ankylosing Spondylitis Pictures MEDLINE plus Ankylosing spondylitis Diagnosis / Symptoms National Library of Medicine Open Directory Project : Health : ... : Arthritis : Ankylosing spondylitis (Other versions: Google AOL LookSmart : Ankylosing spondylitis NOAH: Ankylosing spondylitis NY Online Access to Health Yahoo : Ankylosing spondylitis NMAP : Spondylitis, Ankylosing healthfinder® : Ankylosing spondylitis US Government Ankylosing Spondylitis Pictures MEDLINEplus Health Encyclopedia : Ankylosing spondylitis Symptoms A.D.A.M. / National Library of Medicine

6. What Is Ankylosing Spondylitis Diagnosing treating and surviving ankylosing Spodylitis What is ankylosing spondylitis? ankylosing spondylitis is a form of of an autoimmune disease. What are the symptoms of ankylosing spondylitis? The symptoms of ankylosing spondylitis http://www.myfibrosite.com/users/dwaynebright/products.html

DROP DOWN MENU Fibromyalgia Menu Welcome FMS Home Page Dwaynes Story ... Dwaynes A.S. Story WHAT IS ANKYLOSING SPONDYLITIS? Search this site or the web powered by FreeFind Site search Web search Ankylosing Spondylitis has been a disorder that affects men for years. This page is meant to provide basic information and should not be used as a diagnostic tool. Anyone experiencing sypmtoms should be seen by a licensed medical professional. What is ankylosing spondylitis? Ankylosing spondylitis is a form of chronic inflammation of the spine and the sacroiliac joints. The sacroiliac joints are located in the low back where the sacrum (the bone directly above the tailbone) meets the iliac bones (bones on either side of the upper buttocks). Chronic inflammation in these areas causes pain and stiffness in and around the spine. Over time, chronic spinal inflammation (spondylitis) can lead to a complete cementing together (fusion) of the vertebrae, a process called ankylosis. Ankylosis causes total loss of mobility of the spine. Ankylosing spondylitis is also a systemic rheumatic disease. Therefore, it can cause inflammation in other joints away from the spine, as well as other organs, such as the eyes, heart, lungs, and kidneys. Ankylosing spondylitis shares many features with several other arthritis conditions, such as psoriatic arthritis, reactive arthritis, and arthritis associated with Crohn's disease and ulcerative colitis. Each of these arthritic conditions can cause disease and inflammation in the spine, other joints, eyes, skin, mouth, and various organs. In view of their similarities and tendency to cause inflammation of the spine, these conditions are collectively referred to as "spondyloarthropathies." For more information, please read the following articles; Psoriatic Arthritis, Reactive Arthritis, Crohn's Disease and Ulcerative Colitis.

7. Diagnose-Me: Conditions: Ankylosing Spondylitis ankylosing spondylitis is an autoimmune disease which affects collagen structures, specifically the joints between the vertebrae of the spine. http://www.diagnose-me.com/cond/C553736.html

Home FAQ Start The Analyst Last updated: May 06, 2004 Ankylosing Spondylitis Signs, symptoms and indicators Conditions that suggest it Contributing risk factors Other conditions that may be present ... Treatment recommendations Ankylosing spondylitis is an autoimmune disease which affects collagen structures, specifically the joints between the vertebrae of the spine. The joints and ligaments that normally permit the spine to move become inflamed and stiff. The bones of the spine may grow together, causing the spine to become rigid and inflexible. Other joints such as the hips, shoulders, knees, or ankles also may become involved. Symptoms of ankylosing spondylitis appear most frequently in young men between the ages of 16 and 35. It is less common in women, whose symptoms are often milder and more difficult to diagnose. About 5% of ankylosing spondylitis cases begin in childhood; boys are more likely to have it than girls. When children develop ankylosing spondylitis, it usually begins in the hips, knees, bottoms of the heels or big toes and may later progress to involve the spine. The gene is present in 8% of white Americans and 2-3% of African Americans. About 1% of the adult population has this condition and, as expected, the disease is three times more common in whites than in African Americans.

8. Alopecia Areata,Ankylosing Spondylitis,Antiphospholipid Syndrome,Autoimmune Addi Alopecia Areata,ankylosing spondylitis,Antiphospholipid Syndrome,autoimmune Addison s Disease,autoimmune Hemolytic Anemia,autoimmune Hepatitis,Behcet s Disease http://www.icomm.ca/geneinfo/autoimm.htm

For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY Autoimmune Disease Disorder Types Alopecia Areata Ankylosing Spondylitis Antiphospholipid Syndrome Autoimmune Addison's Disease Autoimmune Hemolytic Anemia Autoimmune Hepatitis Behcet's Disease Bullous Pemphigoid Cardiomyopathy Celiac Sprue-Dermatitis Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) Chronic Inflammatory Demyelinating Polyneuropathy Churg-Strauss Syndrome Cicatricial Pemphigoid CREST Syndrome Cold Agglutinin Disease Crohn's Disease Discoid Lupus Essential Mixed Cryoglobulinemia Fibromyalgia-Fibromyositis Graves' Disease Guillain-Barré Hashimoto's Thyroiditis Idiopathic Pulmonary Fibrosis Idiopathic Thrombocytopenia Purpura (ITP) IgA Nephropathy Insulin dependent Diabetes Juvenile Arthritis Lichen Planus Lupus Ménière's Disease Mixed Connective Tissue Disease Multiple Sclerosis Myasthenia Gravis Pemphigus Vulgaris Pernicious Anemia Polyarteritis Nodosa Polychondritis Polyglandular Syndromes Polymyalgia Rheumatica Polymyositis and Dermatomyositis Primary Agammag-lobulinemia Primary Biliary Cirrhosis Psoriasis Raynaud's Phenomenon Reiter's Syndrome Rheumatic Fever Rheumatoid Arthritis Sarcoidosis Scleroderma Sjögren's Syndrome Stiff-Man Syndrome Takayasu Arteritis Temporal Arteritis/Giant Cell Arteritis Ulcerative Colitis Uveitis Vasculitis Vitiligo Wegener's Granulomatosis (as defined at the American Autoimmune Related Diseases Association

9. Ankylosing Spondylitis ECureMe.com ankylosing spondylitis is a chronic inflammatory disease of the joints of the spine and The underlying cause is thought to involve the autoimmune response (the http://www.ecureme.com/emyhealth/data/Ankylosing_Spondylitis.asp

DisplayAd("468","60"); Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health June 6, 2004 Resource Links Physician Search Your Questions, E-mail Doctor ... Hospital Directory Ankylosing Spondylitis more about Ankylosing Spondylitis Marie-Strumpell disease or rheumatoid spondylitis Ankylosing spondylitis is a chronic inflammatory disease of the joints of the spine and those connecting to the spine, such as the sacroiliac joint. This is an arthritic condition involving stiffness in joints, with resultant pain and stiffness in the back and hips, and difficulty taking deep breaths, due to rib connection to spine. The underlying cause is thought to involve the autoimmune response (the body's immune system mistakenly attacks these joints). The age of onset is usually late teens or early 20's, with a male predominance.

10. Autoimmune News / September 2003 / Autoimmune Disease News -- Graves', Hashimoto an an application for etanercept (brand name Enbrel), for treatment of active ankylosing spondylitis (AS), a chronic inflammatory autoimmune disease affecting http://www.thyroid-info.com/autoimmune/sept2003.htm

The Autoimmune Report, the FREE Monthly News Report, Enter your email address here for a free subscription Or Click Here to Send a "Subscribe" Email THE AUTOIMMUNE REPORT September 2003 From Patient Advocate Mary Shomon, Author of Living Well With Hypothyroidism Living Well With Autoimmune Disease The Thyroid Diet Success Guide , and the Thyroid Guide to Fertility, Pregnancy and Breastfeeding Success This newsletter is located online at: http://www.thyroid-info.com/autoimmune/sept2003.htm Study Suggests Low-Dose Mercury Accelerates Autoimmune Disease Researchers have reported on animal studies that found that exposure to low levels of mercury can speed up and worsen the symptoms of autoimmune disease, even when the exposure occurs before the disease has even developed. These findings may help identify whether mercury exposure can have a similar effect on human development of autoimmune diseases, and the role of low-level and toxic mercury exposure. Find out more about the mercury issue Find Out if Your Thyroid Is Causing Your Symptoms Dr. Ken Woliner walks you through his detailed, step-by-step instructional guide that helps you and your doctor determine if your thyroid could be the cause of your symptoms. Find out the symptoms that should raise a red flag, how to measure your temperature including excellent instructions on how to monitor your basal body temperature! what your doctor should be looking for in a physical exam, and the various blood tests you can request. And Dr. Woliner answers the essential question: If you have normal laboratory tests, could your thyroid still be causing your symptoms?

11. Caring Medical - Symptoms - Ankylosing Spondylitis DESCRIPTION ankylosing spondylitis is a progressive autoimmune disease, which causes inflammation of and arthritic reactions to the spine and large joints. http://www.caringmedical.com/symptoms/condition.asp?condition_id=391

12. Ankylosing Spondylitis ankylosing spondylitis. June 19, 2001 Ankylosis spondylitis is associated with autoimmune diseases http://www.six-paq.com/Health/ankylosing_spondylitis.htm

Ankylosing Spondylitis June 19, 2001 Last Updated: March 10, 2003 Diet related issues regarding Ankylosing Spondylitis Celiacs disease - wheat intolerance Eliminating starch may improve symptoms from Ankylosing Spondylitis Eliminating tomatoes may improve symptoms from Ankylosing Spondylitis Nightshade plants o Potatoes o Tomatoes o Peppers o Eggplants Nightshade toxicity – another view The solanine in potatoes is found almost exclusively in their skin and sprouts (or "eyes"); tomatine is found only in the tomato plant's stem and, early in their development, in unripe, green tomatoes. Green color in both tomatoes and potatoes is a clue that their toxin levels may be dangerously high, although the color comes from an entirely different and harmless process of making chlorophyll. Avoiding green parts effectively reduces the threat of toxicity. 2. Symptom relief NSAIDS (Nonsteroidal Anti-inflammatory Drugs) Hydrocordone (Vicodin, Lorcet, Lortab) Aspirin Naproxen (Naprosyn, Aleve) Feldene Dihydrocodeine (DHC Plus) Sulfasalazine (Azulfidene) Indomethacin (Indocin) Voltarol R or Diclofenac Sodium - NSAID (known in the UK) Prednisone Lodine Voltaren SR Methotrexate Pregnenolone Acetominophen Naprosyn and sulphrozine Decadron Phenylbutazone Butazolidine 600mg to 800 per day.

13. Caring Medical - Treatment Of Ankylosing Spondylitis one woman s tremendous success in treating her autoimmune disease with natural medicine. Or a 25year-old music teacher with ankylosing spondylitis gets pain http://www.caringmedical.com/symptoms/condition_detail.asp?condition_id=391

14. MotherNature.com - The Green Pharmacy Herbal Handbook: Ankylosing Spondylitis and cattle cartilage may help those of us with ankylosing spondylitis (AS component of cartilage, may significantly reduce the symptoms of autoimmune forms of http://www.mothernature.com/Library/Bookshelf/Books/41/12.cfm

Items in cart: Product Total: Add $49.00 for FREE Shipping! Welcome Shopper! Sign in or Sign up. Search Products Library 4 Ways To Shop Brands Health Concern Departments CHAPTER LIST FOR BOOK TITLE: Introduction to the Green Pharmacy Ch.1 Introduction to the Green Pharmacy Ch.2 Entering the Green Pharmacy Ch.3 Putting Safety First Ch.4 Shopping and Harvesting the Green Pharmacy Ch.5 Using the Green Pharmacy Ch.6 Aging Ch.7 Allergies Ch.8 Altitude Sickness Ch.9 Alzheimers Disease Ch.10 Amenorrhea Ch.11 Angina Ch.12 Ankylosing Spondylitis Ch.13 Arthritis Ch.14 Asthma Ch.15 Athletes Foot Ch.16 Backache Ch.17 Bad Breath Ch.18 Baldness Ch.19 Bladder Infections Ch.20 Body Odor Ch.21 Breast Enlargement Ch.22 Breastfeeding Problems Ch.23 Bronchitis Ch.24 Bruises Ch.25 Bunions Ch.26 Burns Ch.27 Bursitis and Tendinitis Ch.28 Cancer Prevention Ch.29 Canker Sores Ch.30 Cardiac Arrhythmia Ch.31 Carpal Tunnel Syndrome Ch.32 Cataracts Ch.33 Chronic Fatigue Syndrome Ch.34 Colds and Flu Ch.35 Constipation Ch.36 Corns Ch.37 Coughing Ch.38 Cuts Scrapes and Abscesses Ch.39 Dandruff Ch.40 Depression Ch.41 Diabetes Ch.42

15. Ankylosing Spondylitis - Arthritis: Health And Medical Information About Arthrit What is ankylosing spondylitis? ankylosing spondylitis is a form of chronic inflammation of the hallmark of an autoimmune disease. What are the symptoms of ankylosing spondylitis? http://www.focusonarthritis.com/script/main/art.asp?articlekey=274&rd=1

16. What Causes Ankylosing Spondylitis? ankylosing spondylitis may be triggered by certain types of bacterial or viral infections that by the body s own immune system is called an autoimmune disease. http://yourmedicalsource.com/library/ankylosingspondylitis/AS_causes.html

Ankylosing Spondylitis Place mouse pointer over this symbol for definition. What Is Ankylosing Spondylitis? What Causes Ankylosing Spondylitis? What Are The Symptoms Of Ankylosing Spondylitis? How Is The Diagnosis Made? ... Additional Sources Of Information Other helpful websites: Yahoo! Health WebMD NIH What Causes Ankylosing Spondylitis? The specific cause of ankylosing spondylitis is unknown, but genetic factors seem to play a role. About 95% of people who have ankylosing spondylitis also have a genetic marker known as human leukocyte antigen-B27 (HLA-B27). About eight people in 100 among American Caucasians are born with the HLA-B27 gene. The gene is much less common among African Americans. Genetic markers are protein molecules found on the surfaces of cells. The HLA markers enable the body's immune system to distinguish between "self" and "other." Ankylosing spondylitis may be triggered by certain types of bacterial or viral infections that activate an immune response that does not shut off after the infection is healed. The immune system then attacks the body's own tissue. A disorder caused by the body's own immune system is called an autoimmune disease. Is Ankylosing Spondylitis Inherited?

17. EMedicine - Ankylosing Spondylitis And Undifferentiated Spondyloarthropathy : Ar family of related disorders that includes ankylosing spondylitis (AS), Reiter syndrome (RS), reactive arthritis (ReA SpAs are the only known autoimmune diseases linked to a classI http://www.emedicine.com/MED/topic2700.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy Last Updated: February 24, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: Marie-Strümpell disease, von Bechterew disease, von Bechterew's disease, spondyloarthropathies, SpAs, AS, rheumatoid spondylitis, UspA, peripheral enthesitis, sacroiliitis, Schober test, cauda equina syndrome, dactylitis, European Spondyloarthropathy Study Group criteria, Amor criteria, New York criteria, Rome criteria, Romanus lesion, bamboo spine, fused spine AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Lawrence H Brent, MD , Chair, Program Director, Associate Professor, Department of Medicine, Division of Rheumatology, Albert Einstein Medical Center, Thomas Jefferson University Lawrence H Brent, MD, is a member of the following medical societies:

18. Ankylosing Spondylitis - Arthritis: Health And Medical Information About Arthrit How inflammation occurs and persists in different organs in ankylosing spondylitis is a the absence of active infection is the hallmark of an autoimmune disease http://www.medicinenet.com/Ankylosing Spondylitis/article.htm

MedicineNet Home Arthritis Home > Ankylosing Spondylitis Advanced Search Printer-Friendly Format Add to Favorites Email to a Friend ... Next page Ankylosing Spondylitis Medical Author: William C. Shiel Jr., MD, FACP, FACR What is ankylosing spondylitis? What causes ankylosing spondylitis? What are the symptoms of ankylosing spondylitis? ... Ankylosing Spondylitis At A Glance What is ankylosing spondylitis? Ankylosing spondylitis is a form of chronic inflammation of the spine and the sacroiliac joints. The sacroiliac joints are located in the low back where the sacrum (the bone directly above the tailbone) meets the iliac bones (bones on either side of the upper buttocks). Chronic inflammation in these areas causes pain and stiffness in and around the spine. Over time, chronic spinal inflammation (spondylitis) can lead to a complete cementing together (fusion) of the vertebrae, a process called ankylosis. Ankylosis causes total loss of mobility of the spine. Ankylosing spondylitis is also a systemic rheumatic disease. Therefore, it can cause inflammation in other joints away from the spine, as well as other organs, such as the eyes, heart, lungs, and kidneys. Ankylosing spondylitis shares many features with several other arthritis conditions, such as

19. Ankylosing Spondylitis - HLA-B27, Symptoms And Treatment Therefore ankylosing spondylitis is often thought of as an autoimmune disease a disease in which the person s own immune system attacks their body. http://hcd2.bupa.co.uk/fact_sheets/html/ankylosing_Spondylitis.html

search home services health information ... BUPA Products and services Health insurance Financial protection Hospitals Care homes ... International cover Visitor interest areas Individuals Business Intermediaries Health professionals ... BUPA members Facilities finder Find local health and fitness facilities World of BUPA BUPA services around the world at bupa.com health information ABC of health Ankylosing spondylitis R E L A T E D L I N K S Download a pdf of this factsheet Published by BUPA's Health Information Team October 2003 Ankylosing spondylitis (AS) is a type of arthritis that mainly affects the spine, where the joints of the spine and the joints between the spine and pelvis become inflamed. This results in pain and stiffness in the neck and back. Although there is no cure for AS, exercise can help relieve symptoms, and medicines are available to reduce pain. ... There is a strong association between ankylosing spondylitis and a gene called HLA-B27. It is thought that this causes the body's immune system to attack the joints of the spine, which is what causes the inflammation. Therefore ankylosing spondylitis is often thought of as an autoimmune disease - a disease in which the person's own immune system attacks their body. However, not everyone with the HLA-B27 gene develops ankylosing spondylitis. Normal spine The spine The spine is made up of 24 bones called vertebrae, plus the sacrum and coccyx. These are linked with joints. There are three main sections of vertebral spine: cervical (neck), thoracic (chest) and lumbar (lower back). In the thoracic section, each vertebrae also has joints with 12 pairs of ribs. Below the lumbar spine is the sacrum, which is actually five vertebrae fused into one bone. This forms a joint with the pelvis (hip bone) on either side, called the sacroiliac joint.

20. Entrez PubMed ankylosing spondylitis an autoimmune disease? Lakomek HJ, Plomann M, Specker C, Schwochau M. Department of Medicine, Endocrinology http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

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