81. Addison's Disease: Adrenal Insufficiency Addison s disease is an endocrine or hormonal disorder that occurs inall age groups and afflicts men and women equally. The disease http://www.niddk.nih.gov/health/endo/pubs/addison/addison.htm

Causes Symptoms Diagnosis Other Tests ... For More Information Addison's disease is an endocrine or hormonal disorder that occurs in all age groups and afflicts men and women equally. The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and nonexposed parts of the body. Addison's disease occurs when the adrenal glands do not produce enough of the hormone cortisol and, in some cases, the hormone aldosterone. The disease is also called adrenal insufficiency, or hypocortisolism. Cortisol is normally produced by the adrenal glands, located just above the kidneys. It belongs to a class of hormones called glucocorticoids, which affect almost every organ and tissue in the body. Scientists think that cortisol has possibly hundreds of effects in the body. Cortisol's most important job is to help the body respond to stress. Among its other vital tasks, cortisol helps maintain blood pressure and cardiovascular function helps slow the immune system's inflammatory response helps balance the effects of insulin in breaking down sugar for energy helps regulate the metabolism of proteins, carbohydrates, and fats

82. Melody's Links To Addison's Disease / Adrenal Insufficiency The Canine Addison's disease Website contains a collection of information about Adrenal Insufficiency, a photo gallery, and an email list all dedicated to our AD dogs. http://www.k9addisons.com/

83. Addison's Disease (HYPOADRENOCORTICISM) THESE TERMS WILL BE USED INTERCHANGEABLY THROUGH THIS TEXT. ADRENAL HORMONES. The Adrenal glands are. located just atop the kidney. areas produce hormones, Addison's disease http://www.marvistavet.com/html/addison_s_disease.html

84. ADDISON'S DISEASE: THE FACTS YOU NEED TO KNOW ADDISON S disease THE FACTS YOU NEED TO KNOW. Written by Paul Margulies,MD WHAT IS ADDISON S disease? Addison s disease is a severe http://www.medhelp.org/nadf/nadf3.htm

ADDISON'S DISEASE: THE FACTS YOU NEED TO KNOW Written by: Paul Margulies, M.D., F.A.C.P., F.A.C.E. Medical Director - NADF Clinical Associate Professor of Medicine, Cornell University Medical College WHAT IS ADDISON'S DISEASE? Addison's disease is a severe or total deficiency of the hormones made in the adrenal cortex, caused by a destruction of the adrenal cortex. There are normally two adrenal glands, located above each kidney. The adrenal glands are really two endocrine ( ductless or hormone producing ) glands in one. The inner part of the adrenal ( called the medulla ) produces epinephrine ( also called adrenaline ) which is produced at times of stress and helps the body respond to "fight or flight" situations by raising the pulse rate, adjusting blood flow, and raising blood sugar. However, the absence of the adrenal medulla and epinephrine does not cause disease. WHAT CAUSES ADDISON'S DISEASE? When Dr. Thomas Addison's' first described this disease in London in 1855, the most common cause was tuberculosis. This remained the leading cause until the middle of the twentieth century when antibiotics progressively reduced TB's incidence. Since then, the major cause of Addison's disease results from an auto-immune reaction in which the body's immune system erroneously makes antibodies against the cells of the adrenal cortex and slowly destroys them. That process takes months to years. There are also several less common causes of Addison's disease: other chronic infections besides tuberculosis, especially certain fungal infections, invasion of the adrenal by cancer cells that have spread from another part of the body, especially the breast; CMV virus in association with AIDS; rarely, hemorrhage into the adrenals during shock; and the surgical removal of both adrenals.

85. Addison's Disease Encyclopedia of Canine Veterinary Medical Information Addison s disease (Hypoadrenocorticism).Addison s disease is also known as hypoadrenocorticism. http://www.vetinfo.com/dencyclopedia/deaddisons.html

Vetinfo Canine Encyclopedia Feline Encyclopedia VetInfo Digest ... Your Turn Encyclopedia of Canine Veterinary Medical Information Addison's disease (Hypoadrenocorticism) Addison's disease is also known as hypoadrenocorticism. It is an insufficient production of adrenal hormones by the adrenal gland. Since these hormones are essential for life, this is an extremely serious disease and it must be treated as such. Adrenal insufficiency can be primary or secondary. Primary adrenocorticism affects salt/potassium balance in the body and glucorticoid as well. Secondary adrenocorticism usually only affects the glucocorticoids. It is not known why primary adrenocorticism occurs but it may be an immune mediated process. Secondary adrenocorticism probably occurs most often when prednisone or other cortisone being administered for medical reasons are suddenly withdrawn. It can occur as a result of pituitary cancer or some other process that interferes with production of hormones that stimulate the adrenal glands. Most dogs with Addison's disease initially have gastrointestinal disturbances like vomiting. Lethargy it also a common early sign. Poor appetite can occur as well. These are pretty vague signs and it is extremely easy to miss this disease. More severe signs occur when a dog with hypoadrenocorticism is stressed or when potassium levels get high enough to interfere with heart function. Dogs with this problem will sometimes suffer severe shock symptoms when stressed, which can lead to a rapid death. When potassium levels get high heart arrythmias occur or even heart stoppage which also is fatal. In some cases, especially secondary Addison's disease, there are no detectable electrolyte changes.

86. MedlinePlus Medical Encyclopedia: Addison’s Disease Addison’s disease. Addison s disease is a hormone deficiency caused bydamage to the outer layer of the adrenal gland (adrenal cortex). http://www.nlm.nih.gov/medlineplus/ency/article/000378.htm

@import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Addison’s disease Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Calling your health care provider Illustrations Endocrine glands Alternative names Return to top Adrenocortical hypofunction; Chronic adrenocortical insufficiency; Adrenal insufficiency Definition Return to top Addison's disease is a hormone deficiency caused by damage to the outer layer of the adrenal gland (adrenal cortex). Causes, incidence, and risk factors Return to top The adrenal glands are located on top of each kidney. They consist of the outer portion (called the cortex) and the inner portion (called the medulla). The cortex produces three types of hormones: sex hormones, glucocorticoid hormones, and mineralocorticoid hormones. The sex hormones, androgens (male) and estrogens (female) affect sexual development and reproduction. The glucocorticoid hormones (such as cortisol) maintain glucose (sugar) regulation, suppress the

87. Http://addisondogs.com/index.html Welcome to AddisonDogs.com. We are a diverse collection of individuals strivingtoward healthy, active lives for our dogs with Addison s disease. http://www.addisondogs.com/

window.resizeTo(800,600); var width = screen.width var height = screen.height document.write("") elcome to AddisonDogs.com including body, mind and spirit Sitemap Bylaws Articles of Inc. Current Board Members ... Contact Us or list-members provide medical advice. All information is for educational purposes and is not intended to diagnose or treat. You are encouraged to visit your vet if you have any concerns about the health of your animals. No material from this website — graphics, photographics, or written material— may be used without express written permission from AddisonDogs.com. © 2003 AddisonDogs.com

88. Information - Addison's Disease Addison s disease (Hypoadrenocorticism). The adrenal glands are situated inthe body at the cranial edge of the kidneys. Signs of Addison s disease. http://www.berkshirevet.com/infoaddison.htm

Addison's Disease (Hypoadrenocorticism) The adrenal glands are situated in the body at the cranial edge of the kidneys. Adrenocortical insufficiency or hypoadrenocorticism results from deficient production of glucocorticoids, mineralcorticoids, or both. Mineralcorticoids are responsible for the reabsorption of sodium and chloride. Decreased mineralcorticoid secretion results in loss of sodium, which causes an increase of potassium in the blood. High blood levels of potassium can lead to life threatening heart problems. Glucocorticoids have a multitude of functions and effects. They are involved in carbohydrate breakdown, they enhance glycogen storage and they surpress systemic immunity. Decreased glucocorticoid secretion can gause gastrointestinal signs such as loss of appetite, vomiting and abdominal pain. Most cases of Addison disease are thought to be immune mediated. It is a relatively uncommon disease in dogs and extremely rare in cats. There may be a genetic predisposition in several breeds of dogs, including standard poodles, Labrador retreivers, and Portugese water spaniels. Signs of Addison's Disease A high index of suspicion is often needed to diagnose this uncommon disease. The trouble with diagnosis is the signs animals have with Addison's are similar to the signs of numerous other conditions. There is no one clinical sign that pinpoints one to diagnose Addison disease. Common clinical findings are depression, weakness, gastrointestinal upset and a slow heart rate.

89. DermIS / Main Menu / DOIA / Addison's Disease / Images DermIS / main menu / DOIA / Addison s disease / images, deutsch español portuguesfrançais. / images for the diagnosis Addison s disease . Click to enlarge. http://dermis.multimedica.de/doia/diagnose.asp?zugr=d&lang=e&diagnr=255400&topic

90. FAQ Addison's Disease Addison s disease. General Information The adrenal The only definitivetest for Addison s disease is the ACTH stimulation test. The patient http://www.iol.ie/~pjmathew/faqadd.htm

Addison's Disease General Information: The adrenal gland is so named because it is located just forward of the kidney ("renal" means kidney). The center of the gland is called the "medulla" and the outer area is called the "cortex." While both areas produce hormones, Addison's disease concerns the hormones produced by the cortex; these hormones are called "corticosteroids." Corticosteroids are the hormones that enable us to adapt physiologically to stress. The "Glucocorticoids" (such as cortisol and related synthetics, prednisone and dexamethasone) act on the mechanics of sugar, fat, and protein metabolism. They gear the metabolism towards the preparation of burning (rather than storing) fuels so as the be ready for a "fight or flight" situation. The "Mineralocorticoids" (such as aldosterone and related synthetic fludrocortisone acetate) influence the electrolytes: sodium and potassium. As a general biological rule, where there's sodium or salt, there's water. When the mineralocorticoids circulate as part of the "fight or flight" preparation, sodium is conserved in anticipation of blood loss so that there will be extra fluid in the vascular compartment (spare blood). When sodium is conserved, potassium is lost as part of the biological balance. This whole picture of fat mobilization, sodium conservation etc. which is part of the "fight or flight" preparation is far more complex than can be reviewed here but the bottom line is:

91. Boards - Addison's Disease MayoClinic Drug Search. MedLinePlus Addison s disease. Threads in BoardAddison s disease, Board Tools. http://www.healthboards.com/boards/forumdisplay.php?f=8

92. Addison's Disease Info Addison s disease or Primary Adrenal Insufficiency. The estimated Addison sdisease can cause irritability and depression. Because of http://www.julies-story.org/adrenal/addison.htm

See also; Addison's Disease Info Acute Adrenal Crisis Emergency Injections Diagnosis ... Questionnaire Respondents Comments Thomas Addison The Endocrine System Updated Monthly You can find the latest news on this disorder in the Medical Updates section. Addison's Disease or Primary Adrenal Insufficiency The estimated prevalence of Addison's disease in industrialised countries is 117 per million, which translates into approximately 35,000 cases in the US. Between 80 and 90% of cases of Addison's disease are caused by an autoreactive process of activated immune cells directed against adrenocortical 21-hydroxylase (an enzyme involved in the synthesis of glucocorticoids and aldosterone). The other 10 to 20% of cases are caused by tuberculosis, HIV, sarcoidosis, amyloidosis, bilateral metastases, adrenoleukodystrophy, adrenal haemorrhage and congenital hypoplasia. (1) Introduction: Addison's disease, or primary adrenal insufficiency, is most commonly caused by an autoimmune destruction of cells in the adrenal cortex. Unfortunately, the clinical presentation of the disease is often nonspecific and the 'text book' patterns of electrolyte disturbance infrequently observed. Addison's disease is a rare endocrine, or hormonal disorder that affects all age groups and afflicts men and women equally. The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and nonexposed parts of the body.

93. NORD - National Organization For Rare Disorders, Inc. Addison s disease. To purchase fulltext report ($7.50) Copyright 1985, 1986,1988, 1991, 1993, 1994, 1997, 1999, 2003 Synonyms of Addison s disease http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Addison's Dis

94. Addison's Disease - Encyclopedia Article About Addison's Disease. Free Access, N encyclopedia article about Addison s disease. Addison s disease in Free onlineEnglish dictionary, thesaurus and encyclopedia. Addison s disease. http://encyclopedia.thefreedictionary.com/Addison's disease

Dictionaries: General Computing Medical Legal Encyclopedia Addison's disease Word: Word Starts with Ends with Definition Addison's disease (also known as chronic adrenal insufficiency , or hypocortisolism ) is a rare endocrine The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs. It does not include exocrine glands such as salivary glands, sweat glands and glands within the gastrointestinal tract. Signal transduction of some hormones with steroid structure involves nuclear hormone receptor proteins that are a class of ligand activated proteins that, when bound to specific sequences of DNA serve as on-off switches for transcription within the cell nucleus. These switches control the development and differentiation of skin, bone and behavioral centers in the brain, as well as the continual regulation of reproductive tissues. Click the link for more information. disorder. It is estimated that it affects about 1 to 5 in 100,000 people. It occurs when the adrenal glands In mammals, the

95. Diseases: Johns Hopkins Autoimmune Disease Research Center Addison s disease. Common test used to diagnose Addison s disease includeACTH Stimulation Test; InsulinInduced Hypoglycemia Test,; http://autoimmune.pathology.jhmi.edu/diseases.cfm?systemID=3&DiseaseID=16

96. Great Dane: DaDane 11/24/03 Addison s disease in the Great Dane –. November 24, 2003 – We ve beendiscussing hypoadrenocorticism, or Addison s disease, in the Great Dane. http://www.ginnie.com/DaDane369.shtml

/***************************************************************************** top navigation menu ******************************************************************************/ Created: 11/24/03 Links: Newest DaDane Previous DaDane Archived DaDanes Available now DaDane of DaWeek Coming soon Prints See last week. ) Addison's is not widely known to the general public and the condition is often misdiagnosed by veterinarians due to the fact that symptoms often mimic those of other diseases. In fact, Addison's Disease is often referred to as "The Great Pretender." While AD isn't exactly prevalent in our breed, it has a definite presence and you should know something about it because, if left undiagnosed, Addison's can kill your dog. If you have an Addison's Dane, you and your dog may be able to help our breed! email , or by phone at (432) 684-8940. Confidentiality is assured, as all dogs will be assigned numbers for the study.

97. Addison's Disease Information- The Addison Files- The main purpose of this site is to provide an international database for Addisonssufferers. This disease is still relatively unusual worldwide and it is easy http://www.xgz55.dial.pipex.com/index.shtml

Welcome to the revised and updated Addisons Files. I knew it was time to revise the site when my daughter left a message in the guestbook telling me to update the family picture (which is now over 3 years old)! The main purpose of this site is to provide an international database for Addisons sufferers. This disease is still relatively unusual worldwide and it is easy for sufferers to feel alone and misunderstood. Please sign the guestbook if you want to. Thank you to all those who have left appreciative comments. Some of the links were out of date or had moved. These have been amended. I hope to add to them. I do not intend this site to be a medical textbook about Addison's Disease. There are many excellent sites about the medical facts. I would like to show others how they can live with the disease, and , hopefully be an inspiration by showing how life can go on. I would be very interested to hear from others with Addisons with particular reference to what you have achieved since being diagnosed. You can read my story to get the ball rolling! Please send me any stories that you think would be of benefit to others suffering from Addisons.

98. MediClass About this Category. Name Addison s disease Number of Subcategories 0 Numberof Links 3 Posted Messages 0 Hits 295 Articles 0 Editors Radone, Julaf. http://www.mediclass.org/pages/directory.php?idcat=292

99. Feline Hyperthyroidism This page. is currently under repair. http://www.vetmed.auburn.edu/endo/faq.html

This page is currently under repair.

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