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Sickle Cell Anemia: more books (100)

A multidisciplinary health care team's efforts to improve educational attainment in children with sickle-cell anemia and cerebral infarcts.(Research Papers): An article from: Journal of School Health by Allison King, Sonya Herron, et all 2006-01-01
Sickle cell anemia: An entry from Thomson Gale's <i>Gale Encyclopedia of Science, 3rd ed.</i> by Julia Barrett, 2004
Sickle cell success: promising rays of hope amid the continuing crusade for a cure.(sickle cell anemia)(Disease/Disorder overview): An article from: Ebony by Joy T. Bennett, 2008-11-01
Science & Medicine Magazine Sept/Oct 1994 (Vol. 1 No. 4, H. Pylori Binding, Arterial Plaques, Sickle Cell Anemia, Insulin Resistance) by various, 1994
Sickle Cell Anemia - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker, 2007-07-18
Sickle Cell Anemia (Health Alert 7) by Ruth Bjorklund, 2010-09
Myonecrosis in sickle cell anemia: case report and review of the literature.(Case Report): An article from: Southern Medical Journal by Perla Vicari, Ruth Achkar, et all 2004-09-01
21st Century Ultimate Medical Guide to Sickle Cell Anemia - Authoritative Clinical Information for Physicians and Patients (Two CD-ROM Set) by U.S. Government, 2009-07-01
Species II: 1998 in Film, Natasha Henstridge, Michael Madsen, Marg Helgenberger, Sickle Cell Anemia
NHLBI sickle cell and stroke risk trial halted: young sickle cell anemia patients who are at high risk for stroke can't forgo regular blood transfusions.(Clinical ... An article from: Family Practice News by Doug Brunk, 2005-02-01
Sickle cell/stroke prevention trim halted.(News)(Stroke Prevention Trial in Sickle Cell Anemia II): An article from: Pediatric News by Doug Brunk, 2005-01-01
1949 in Science: Spaceflight Before 1951, Sickle Cell Anemia, a Molecular Disease, Communication Theory of Secrecy Systems, 1949 in Archaeology
Sickle cell anemia: A selected annotated bibliography by Lenwood G Davis, 1978
Sickle cell anemia: An entry from Thomson Gale's <i>Gale Encyclopedia of Children's Health: Infancy through Adolescence</i> by Monique, Ph.D. Laberge, 2006

lists with details

Sickle Cell Anaemia - Wikipedia, The Free Encyclopedia
This is achieved by reactivating fetal hemoglobin production in place of the hemoglobin S that causes sickle cell anemia. Hydroxyurea
http://en.wikipedia.org/wiki/Sickle_cell_anaemia

Extractions: Sickle-shaped red blood cells Sickle cell anaemia SCA ) is a common genetic disease which causes the red blood cells of a sufferer to be shaped like sickles , instead of the normal rounded shape. This causes the cells to become stuck in capillaries which deprives the body of oxygen and causes inflammation . The disease usually occurs in periodic painful attacks, eventually leading to damage of some internal organs, stroke , or anaemia , and usually resulting in early death. edit The first approved drug for the treatment of sickle cell anaemia, hydroxyurea , was shown to decrease the number and severeness of attacks in a study in 1995 and shown to increase survival time in a study in 2003. This is achieved by reactivating fetal hemoglobin production in place of the hemoglobin S that causes sickle cell anemia. Hydroxyurea had previously been used as a cancer drug, and there is some concern that long-term use may be harmful, but it is likely that the benefits outweigh the risks. edit The gene allele responsible for sickle cell anaemia is incompletely recessive . A person who receives the defective gene from both father and mother develops the disease; a person who receives one defective and one healthy allele remains healthy, but can pass on the disease and is known as a
HuGE Review - Sickle Hemoglobin (Hb S) Allele And Sickle Cell Disease
Individuals who are affected with sickle cell anemia have two copies of this beta globin variant and the primary hemoglobin present in their red blood cells is
http://www.cdc.gov/genomics/hugenet/reviews/sickle.htm

Extractions: Medical Literature Search At-A-Glance Beta globin is a major component of adult hemoglobin. The gene for beta globin is located on chromosome 11 and there are over 475 allelic variants. One of these variants, sickle hemoglobin ( Hb S ), is responsible for sickle cell disease, one of the most prevalent genetic diseases, affecting over 50,000 Americans. Most individuals with sickle cell disease have African and Mediterranean ancestry. It is believed that the high frequency of the (
NHLBI, Sickle Cell Anemia
Facts About sickle cell anemia. sickle cell anemia is an inherited blood disorder, characterized primarily by chronic anemia and periodic episodes of pain.
http://www.nhlbi.nih.gov/health/public/blood/sickle/sca_fact.htm

Extractions: HOME SITE INDEX CONTACT US TIPS ... Publications Sickle cell anemia is an inherited blood disorder, characterized primarily by chronic anemia and periodic episodes of pain. This fact sheet provides concise, accurate information on the causes, populations affected, signs and symptoms, diagnoses, and treatments. 6 pages. NIH Publication Number: 96-4057 You may obtain the document in the following ways: [Plain text (ASCII) document, 19 K]
Medical References: Sickle Cell Disease
One of the most serious complications of sickle cell anemia is stroke, a bleed or blockage of blood within the blood vessels of the brain.
http://www.marchofdimes.com/professionals/681_1221.asp

Extractions: It is an inherited disease of red blood cells which can cause attacks of pain, damage to vital organs, risk of serious infections and can lead to early death. Sickle cell disease affects the main protein inside the red blood cells called hemoglobin. The disease occurs when a person inherits one sickle cell gene from each parent or a combination of one sickle cell gene plus one of several other abnormal hemoglobin genes. Hemoglobin in the red blood cells carries oxygen from the lungs and takes it to every part of the body. The main hemoglobin in the red blood cells of people with sickle cell disease is not normal. Red blood cells containing mainly normal hemoglobin are round and flexible. In people with sickle cell disease, the abnormal hemoglobin forces the cells to lose their normally round and flexible shape, becoming distorted and rigid. Under a microscope, these abnormal cells may look like the C-shaped farm tool called a sickle. Sickle cells tend to become trapped and to be destroyed in small blood vessels (veins and arteries), the spleen, the liver and other organs. This results in a shortage of red blood cells, or anemia. Anemia can cause an affected child to be pale, short of breath, easily tired and have slowed growth and physical development. Certain conditions, such as infections or enlargement of the spleen, may worsen the anemia by speeding up destruction of red blood cells. Infections also can reduce red blood cell production, leading to worsening of anemia.
Sickle Cell Anemia Case Study
Biology 296A. sickle cell anemia Webpage. Table of Contents. Part 1 Discovery and Biological Basis. Test Yourself. Part 2 Molecular
http://www.nslc.wustl.edu/courses/Bio296A/allen/sicklecell/sicklecell.html
Biogeography And Ecology Of Sickle Cell Anemia
Biology 296A. Page III. Biogeography and Ecology of sickle cell anemia. A. The Unique Geographic Distribution Pattern of SickleCell Anemia.
http://www.nslc.wustl.edu/courses/Bio296A/allen/sicklecell/part3/biogeography.ht
AllRefer Health - Sickle Cell Anemia (Anemia - Sickle Cell, Hemoglobin SS Diseas
sickle cell anemia (Anemia Sickle Cell, Hemoglobin SS Disease (Hb SS), Sickle Cell Disease) information center covers causes, prevention, symptoms, diagnosis
http://health.allrefer.com/health/sickle-cell-anemia-info.html

Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Anemia - Sickle Cell, Hemoglobin SS Disease (Hb SS), Sickle Cell Disease Definition Sickle cell anemia is an inherited disease in which the red blood cells, normally disc-shaped, become crescent shaped. As a result, they function abnormally and cause small blood clots. These clots give rise to recurrent painful episodes called "sickle cell pain crises."
AllRefer Health - Sickle Cell Anemia Support Groups (Anemia - Sickle Cell, Hemog
sickle cell anemia (Anemia Sickle Cell, Hemoglobin SS Disease (Hb SS), Sickle Cell Disease) information center covers Support Groups. sickle cell anemia.
http://health.allrefer.com/health/sickle-cell-anemia-support.html

Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Anemia - Sickle Cell, Hemoglobin SS Disease (Hb SS), Sickle Cell Disease Sickle Cell Anemia Support Groups Sickle cell anemia, like other chronic, life-threatening diseases, can cause great stress to the patient and family members. Joining a support group, where members share common experiences and problems, can relieve this stress. See sickle cell anemia - support group
Hardin MD : Sickle Cell Anemia
From the University of Iowa, the *best* lists of Internet sources in sickle cell anemia. sickle cell anemia. sickle cell anemia Pictures.
http://www.lib.uiowa.edu/hardin/md/sicklecellanemia.html
ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies:
25 studies were found. 1. Recruiting, Evaluation of Hydroxyurea Plus Larginine or Sildenafil to Treat sickle cell anemia Condition sickle cell anemia.
http://www.clinicaltrials.gov/ct/gui/action/FindCondition?ui=D000755&recruiting=
Clinical Trial: Pediatric Hydroxyurea In Sickle Cell Anemia (BABY HUG)
Pediatric Hydroxyurea in sickle cell anemia (BABY HUG). Condition, Treatment or Intervention, Phase. Blood Disease Anemia, Sickle Cell, Drug Hydroxyurea, Phase III.
http://www.clinicaltrials.gov/ct/show/NCT00006400?order=5
Pregnancy And Sickle Cell Anemia
Pregnancy and sickle cell anemia. I have sickle cell anemia but my partner does not. We are considering having a child and would
http://www.womenshealth.org/a/pregnancy_sickle_cell_anemia.htm

Extractions: Pregnancy and Sickle Cell Anemia I have sickle cell anemia but my partner does not. We are considering having a child and would like to know the risks of conceiving under these circumstances. For a woman with sickle cell anemia who is interested in having children, it is ideal that she pursues supportive counseling and healthcare before she conceives. She needs both a high-risk obstetrician and a hemotologist. If the pregnancy is a surprise, she should seek medical attention as soon as she suspects she might be pregnant. The pregnancies are at higher risk of spontaneous abortion, premature labor, pseudo-toxemia and cesarean section. The fetuses are more likely to have growth lags, and more trouble with the stresses of labor and delivery. After the birth, all women are more likely to have infections and blood clots, but the risk for sickle cell mothers is even greater.
Sickle Cell Anemia
sickle cell anemia. One the first symptom of sickle cell anemia in children is an unusual swelling of the fingers and toes (hand crisis).
http://www.dbpeds.org/conditions/conditions.cfm?Abbrev=sickle
Health & Medical > Sickle Cell Disease
Treating Children with Sickle Cell Disease, ? Child with sickle cell anemia Suffering from Frequent Colds, ? Vaccinations after a Splenectomy, ?
http://www.drspock.com/topic/0,1504,467,00.html

Extractions: The Dr. Spock Company and the Discovery Health Channel reveal the human face of a little understood genetic disorder in the television special Sickle Cell: The Forgotten Disease (check your local TV listings for dates and times). Learn more about sickle cell disease in the following articles written by experts in the field. Sickle Cell Disease Topics Sickle Cell: The Forgotten Disease Puts a Human Face on a Little Understood Genetic Disorder Sickle Cell Disease: The Basics The Subtle Differences of Sickle Cell Syndromes ... Treating Sickle Cell Disease with Bone Marrow Transplantation Questions From Other Parents The Lifespan for a Person with Sickle Cell Disease Lack of Emphasis on Sickle Cell Disease How Sickle Cell Disease Is Inherited Treating Children with Sickle Cell Disease ... Ensuring that a Child Won't Have Sickle Cell CONSUMER ALERTS CPSC Warns: Summer Fun Brings More Emergency Room Visits CPSC, K'NEX Industries Announce Recall of Children's Toys
Sickle Cell Anemia
sickle cell anemia. Definition sickle cell anemia is an inherited disease in which the red blood cells, normally discshaped, become crescent shaped.
http://www.healthscout.com/ency/article/000527.htm

Extractions: Channels Home Today Women Men ... Drug Checker Advertisement Disease Injury Nutrition Poison ... Prevention Definition: Sickle cell anemia is an inherited disease in which the red blood cells, normally disc-shaped, become crescent shaped. As a result, they function abnormally and cause small blood clots. These clots give rise to recurrent painful episodes called "sickle cell pain crises." Causes, incidence, and risk factors: Sickle cell anemia is caused by an abnormal type of hemoglobin (oxygen carrying molecule) called hemoglobin S. It is inherited as an autosomal recessive trait that is, it occurs in someone who has inherited hemoglobin S from both parents. Someone who inherits hemoglobin S from one parent and normal hemoglobin (A) from the other parent will have sickle cell trait . Approximately 8% of African Americans have sickle cell trait. Someone who inherits hemoglobin S from one parent and another type of abnormal hemoglobin from the other parent will have another form of sickle cell disease, such as sickle cell-b
Sickle Cell Anemia
sickle cell anemia is an inherited chronic anemia in which the red blood cells become sickle or crescentshaped. What are the symptoms of sickle cell anemia?
http://www.vitacost.com/science/hn/Concern/Sickle_Cell_Anemia.htm
Sickle Cell Anemia And Thalassemias
sickle cell anemia and thalassemias. To begin the lecture, click the START button above. If you are the first time visitor, you might
http://www.pitt.edu/~super1/lecture/lec10781/
Sickle Cell Anemia
sickle cell anemia. Definition sickle cell anemia primarily affects people with African, Mediterranean, Middle Eastern, and Indian ancestry.
http://www.chclibrary.org/micromed/00065190.html

Extractions: Sickle cell anemia is an inherited blood disorder that arises from a single amino acid substitution in one of the component proteins of hemoglobin. The component protein, or globin, that contains the substitution is defective. Hemoglobin molecules constructed with such proteins have a tendency to stick to one another, forming strands of hemoglobin within the red blood cells. The cells that contain these strands become stiff and elongatedthat is, sickle shaped. Description Sickle-shaped cellsalso called sickle cellsdie much more rapidly than normal red blood cells, and the body cannot create replacements fast enough. Anemia develops due to the chronic shortage of red blood cells. Further complications arise because sickle cells do not fit well through small blood vessels, and can become trapped. The trapped sickle cells form blockages that prevent oxygenated blood from reaching associated tissues and organs. Considerable pain results in addition to damage to the tissues and organs. This damage can lead to serious complications, including
Cerebrovascular Accident In Sickle Cell Anemia
Cerebrovascular Accident in sickle cell anemia, Book, Home Page.
http://www.fpnotebook.com/HEM45.htm

Extractions: Home About Links Index ... Editor's Choice document.write(code); Advertisement Hematology and Oncology Hemoglobin Anemia ... Thalassemia Assorted Pages Hemoglobinopathy Sickle Cell Anemia Cerebrovascular Accident in Sickle Cell Anemia Hand Foot Syndrome ... Priapism in Sickle Cell Anemia Cerebrovascular Accident in Sickle Cell Anemia Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Sarcoma Surgery Symptom Evaluation Vascular Page Hemoglobin Index Approach Anemia Thalassemia Sickle Sickle Complications CVA Sickle Complications Hand Foot Sickle Complications Hematuria Sickle Complications Priapism Epidemiology: Incidence Children: 5% Lifetime risk: 25% Pathophysiology Blockage of Internal Carotid Artery Management: Exchange Transfusion s Reduce proportion of Hemoglobin Maintain this level through childhood Search other websites for this topic
TUTORIAL: Sickle-cell Anemia
shaped. sickle cell anemia glossary. (Not updated to V.3.2!). Using the Biology WorkBench. treatment. Treatments of sickle cell anemia
http://www.bioquest.org/bioinformatics/module/tutorials/Sickle_Cell_Anemia/

Extractions: mgrim@uiuc.edu Using the Biology Workbench , we will examine hemoglobin and the sequence of amino acids that make up this protein. This tutorial will demonstrate the simple mutation in the hemoglobin protein that single-handedly causes a terrible disease. From this mutation, we will look at the three-dimensional structure of the hemoglobin protein using a molecular imaging program. The ability to visualize and manipulate hemoglobin adds a dimension of understanding to the mechanism that causes the characteristic sickle-shaped red blood cells of sickle cell anemia. Sickle cell anemia is a disease in which the patient's red blood cells have an abnormal shape much like that of a sickle. These sickled red blood cells are very fragile and the result is severe anemia, or decreased number of red blood cells. The disease causes many painful symptoms in patients. The abnormal shape of the cells in individuals with sickle cell anemia comes from a defective protein within the blood cells themselves. This defective protein is hemoglobin. The normal hemoglobin protein is made up of four parts, and therefore called a tetramer. Each part of the tetramer has the ability to bind an oxygen molecule and carry it from the lungs to the tissues in which oxygen is needed. When the defective hemoglobin in sickle cell anemia, referred to as Hb S, does not have an oxygen molecule bound, it tends to form a precipitate made up of lots of hemoglobin proteins stuck to each other. This precipitate is what causes the red blood cells to become sickle-shaped.

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